ライフサイエンスコーパス: replacement

1 al and subsequent methadone or buprenorphine replacement.

2 serotypes increased, which suggests serotype replacement.

3 eviously suggested Late Neolithic population replacement.

4 ent guidelines recommend prompt aortic valve replacement.

5 ents eligible for transcatheter aortic valve replacement.

6 mography within 3 months before aortic valve replacement.

7 ient donors, both for insertion and for gene replacement.

8 rity of TAVR as compared with surgical valve replacement.

9 d not differ before and 3 months after valve replacement.

10 r extreme risk for conventional mitral valve replacement.

11 ent and from 16.8% to 53.7% for mitral-valve replacement.

12 and after previous prophylactic aortic root replacement.

13 in the formation of a structurally distinct replacement.

14 ion recovery post-transcatheter aortic valve replacement.

15 ate valve sizing is critical in aortic valve replacement.

16 valve-related complications compared with MV replacement.

17 b (rHb) Kirklareli containing the alpha H58L replacement.

18 or loss of muscle, and accompanying fibrotic replacement.

19 For total knee replacement, 10-year implant survival rate was 96.1% (95

20 edical issues, mainly ongoing immunoglobulin replacement (14; 45%), cutaneous viral warts (7; 24%), s

21 with OVX, but was re-established by acute E2 replacement (3 h, intraperitoneal).

22 teoarthritis (4.00, 95% CI 3.32-4.81), joint replacement (6.02, 95% CI 4.66-7.77), osteoporosis (2.69

23 ngly associate with osteoarthritis total hip replacement: a missense variant, c.1141G>C (p.Asp369His)

24 towards disease-associated single amino acid replacements affecting protein stability and function.

25 ach can be used to efficiently generate gene replacements allowing for modulation of protein levels f

26 Serial crystallographic data for molecular replacement already converges in 1,000-10,000 diffractio

27 nging from -9 to +19 mg/kg) between adjacent replacement and control plots during two boro seasons.

28 ting the importance of implementing full LSL replacement and efficient risk communication.

29 cement, from 11.5% to 51.6% for aortic-valve replacement and from 16.8% to 53.7% for mitral-valve rep

30 nsates for these vacancies by substitutional replacement and is responsible for the generation of the

31 transmitted through population movement and replacement and locate putative focal areas for a set of

32 mon finding after transcatheter aortic valve replacement and often result in permanent pacemaker (PPM

33 (TMVR) for patients with failed mitral valve replacement and repair.

34 As enzyme replacement and substrate reduction therapies are expens

35 nges the increasing trend for more total hip replacements and total knee replacements to be done in t

36 At 682 US hospitals, 70295 SAVR, 19913 MV replacement, and 17037 MV repair procedures were perform

37 range [IQR], 23-76) SAVR, 13 (IQR, 6-22) MV replacement, and 9 (IQR, 4-19) MV repair procedures.

38 timed injection series, pharmacology and ion replacement, and optogenetic activity studies.

39 mplications of symbiont gains, switches, and replacements, and identify future research directions th

40 These results pave the way towards a gene replacement approach for OPMD treatment.

41 e demonstrate that parasites undergoing coat replacement are only vulnerable to clearance via early I

42 Viral gag gene replacements are influenced by host restriction genes Fv

43 lineages consistently supported that radical replacements are more likely to be deleterious than cons

44 lates strongly with the degree of fibrofatty replacement at histologic analysis.

45 An arginine-to-histidine replacement at residue 435 in the binding domain of IgG3

46 c root enlargement (ARE) during aortic valve replacement (AVR) allows for larger prosthesis implantat

47 ctreotide (OCT), and insulin (INS) for basal replacement; B) overnight saline (SAL) infusion followed

48 uggest pro-RGC molecular approaches for cell replacement-based therapies for glaucoma and other optic

49 nts who underwent transcatheter aortic valve replacement between the years 2011 and 2014.

50 Patients were sampled with replacement (bootstrapping) to match the US epidemiologi

51 he best characterized mechanism of stem cell replacement, but other mechanisms could also be deployed

52 plete knockdown of endogenous PABPN1 and its replacement by a wild-type PABPN1 substantially reduces

53 bration bands at ca. 730 cm(-1) upon solvent replacement by adsorbed MOP.

54 Adenosine replacement by intra-articular injection of liposomal su

55 of mitochondrial genes and their functional replacement by new nuclear factors are important in mode

56 ects of dietary saturated fat intake and its replacement by other types of fats and carbohydrates on

57 y impact of sodium reduction and its partial replacement by potassium chloride in pizza dough and cru

58 We search for replacements by applying screening criteria to a compreh

59 The PFOA replacement chemical GenX was detected at all downstream

60 ospheric chemistry of (CF3)2CFCN, a proposed replacement compound for the industrially important sulf

61 from patients with OA undergoing total knee replacement decreased expression of senescent and inflam

62 Isoenergetic replacement does not result in a substantial increase in

63 criminates supraphysiological glucocorticoid replacement doses in patients with CAH.

64 knock-in (reporters or recombinases) or gene replacement (e.g., conditional knockout alleles containi

65 ibution including transcatheter aortic valve replacement eligibility in low-risk patients across 37 a

66 t R, and SAPIEN 3 transcatheter aortic valve replacement enrolled in the RESOLVE study (Assessment of

67 sought to find the reasons for this unusual replacement event.

68 Treatment with replacement factor can lead to the development of inhibi

69 Evaluating the association of hs-cTnT with replacement fibrosis and progression of structural heart

70 c magnetic resonance for characterization of replacement fibrosis by late gadolinium enhancement.

71 y is characterized by cardiomyocyte loss and replacement fibrosis.

72 ofluorocarbons will be phased down and, thus replacement fluids must be found.

73 o investigate the occurrence and identity of replacement fluorinated compounds in surface water and s

74 Currently, systemic hormone replacement for cisgender adults requires a nuanced disc

75 e very long-term outcome after MV repair and replacement for degenerative mitral regurgitation with a

76 for a limited time, but is not an effective replacement for existing vector control.

77 tive for existing lithium-ion batteries or a replacement for lithium metal in Li-O2 and Li-S batterie

78 e PGM-free catalyst holds great promise as a replacement for Pt in future PEMFCs.

79 78 patients undergoing surgical aortic valve replacement for severe aortic stenosis between 2012 and

80 min D Metabolites in Frozen Human Serum as a replacement for SRM 972, which is no longer available.

81 the suitability of NT-ES-beta-cells for cell replacement for type 1 diabetes and provide proof of pri

82 ame retardants (FRs) have been introduced as replacements for banned or restricted chemicals, but muc

83 Total joint replacements for end-stage osteoarthritis of the hip and

84 ns are actively being explored as biomimetic replacements for IVIG therapy, which is deployed to mana

85 We recently found that amides as non-ionic replacements for phosphodiesters may be useful modificat

86 toxicity and biodegradability, are potential replacements for synthetic surfactants.

87 uding refraction error, wearing age and lens replacement frequency.

88 stantially for aortic-valve and mitral-valve replacement, from 11.5% to 51.6% for aortic-valve replac

89 d BaSnO3 (LBSO) perovskite would be an ideal replacement given its electron mobility and electronic s

90 Transcatheter aortic valve replacement has become the procedure of choice for inope

91 ent years, use of transcatheter aortic valve replacement has expanded to include patients at intermed

92 g metabolic effects of opioid withdrawal and replacement have not been examined.

93 Following gene inactivation and replacement in human cells, we demonstrate that CENP-A m

94 ostpone or prevent the need for aortic valve replacement in patients with asymptomatic AS.

95 Surgical aortic valve replacement in patients with small annular dimensions is

96 strogen level to drop 100-fold, the estrogen replacement in preterm infants is physiological.

97 studies have shown potential benefit of gene replacement in RPE65-mediated inherited retinal dystroph

98 tients undergoing transcatheter aortic valve replacement in Switzerland between February 2011 and Feb

99 ) incorporation occurs through (i) metal (M) replacement in the framework nodes (type I), (ii) metal

100 latory effect of phosphorylation is shown by replacement in the oocyte with a phosphorylation-resista

101 Genome-wide analysis shows that nonecotropic replacements in the progenitor ecotropic MLV genome are

102 are determined using the method of molecular replacement, in which known related structures are rotat

103 emonstrate that a complete Neanderthal mtDNA replacement is feasible over this time interval even wit

104 The only functional replacement is methionine, which coordinates F(-) throug

105 Thus, miR-28 replacement is uncovered as a novel therapeutic strategy

106 ement strategies for in vitro engineering of replacement kidney tissue, and to devise strategies to s

107 derlying osteoarthritis at baseline and knee replacement (KR) associated with meniscal surgery in sub

108 After aortic valve replacement, left ventricular afterload is often charact

109 tonuc genes, but range expansion and species replacement likely promoted massive mtDNA introgression.

110 ts also depend strongly on the comparison or replacement macronutrient.

111 Transcatheter aortic valve replacement might be a good alternative; however, compar

112 We speculate that estrogen replacement might partially restore neurogenesis in huma

113 Allelic replacement mutagenesis of cpt in T. denticola resulted

114 tudied the functional impact of deletion and replacement mutants of Gly-457 and its two adjacent resi

115 The glycine replacement mutants were devoid of transport activity, b

116 itting multiple sclerosis (RRMS) have higher replacement mutation frequencies than observed in health

117 zed the outcome after MV repair (n=1709) and replacement (n=213) overall, by propensity score matchin

118 stem cells (MSCs) appeared to contribute in replacement of 40% and 13% host hepatocytes, respectivel

119 The replacement of 75% of fat, for both types of mucilage, h

120 major challenge facing the discipline is the replacement of a generation of clinical microbiologists.

121 The ongoing efforts dedicated to the replacement of a lab-based detector by a cellphone with

122 Through careful SAR, the successful replacement of a polar pyrazole group by a simple chloro

123 e report a comprehensive study of systematic replacement of a single phosphate with an amide linkage

124 wave at 60,000 years ago and the subsequent replacement of all indigenous populations, is in need of

125 olding conformation triggered by the Glu-145 replacement of Asp.

126 lacial cycles, likely causing rapid regional replacement of biota.

127 h their combined role in hydrophobic gating, replacement of both Leu residues with the isosteric but

128 ains unclear, however, and it is likely that replacement of colonized water reservoirs may be require

129 Metasurfaces have facilitated the replacement of conventional optical elements with ultrat

130 The replacement of current petroleum-based plastics with sus

131 Surprisingly, in AOX1A, replacement of CysI by alanine, which cannot form a (thi

132 nd IHD mortality for theoretical, isocaloric replacement of dietary fatty acids (FAs) in quintiles (1

133 itive detection of dsDNA based on the strand replacement of dsDNA by peptide nucleic acid (PNA) and t

134 Due to the strand replacement of dsDNA by PNA, dsDNA can be directly detec

135 ifference is significantly reduced by either replacement of extracellular Ca(2+) with Mg(2+) or the a

136 is is supported by further observations that replacement of extracellular Cl(-) with gluconate(-) dim

137 nerate free holes (p-type doping), while the replacement of Fe(2+) by Ga(3+) cations, taking place in

138 her insertion of exogenous DNA (knock-in) or replacement of genomic segments is very poor.

139 nt starch and dietary fiber content with the replacement of green banana flour (up to a fivefold impr

140 Replacement of H2Q with the higher-potential EPTM, 2-chl

141 a major defect in CD4 binding induced by the replacement of H375 by a serine.

142 ough careful synthesis and characterization, replacement of KBe2 BO3 F2 (KBBF) by a Be-free DUV NLO m

143 ream across the region, as well as continued replacement of large-stream fishes by small-stream fishe

144 still help prioritize both leak repairs and replacement of leak-prone sections of distribution lines

145 Strikingly, replacement of leucine(973) in the juxtamembrane region

146 An example of such a barrier is that replacement of lost neurons may be insufficient because

147 Cell replacement of lost neurons using enteric neural stem ce

148 and valve repair or replacement surgery, the replacement of multiple valves, aortic root reconstructi

149 his leads to clogging, malodor, and possible replacement of nonwater urinals with flush urinals.

150 ycin-resistant enterococci (VRE) through the replacement of peptidoglycan (PG) stem terminal d-Ala-d-

151 plete structural understanding and potential replacement of pharmaceutically relevant PEGs by alterna

152 cused on questions related to the repeal and replacement of portions of the Affordable Care Act (ACA)

153 vestigation was conducted, with the eventual replacement of radiotracers with stable isotopically lab

154 tween stability and plasticity, facilitating replacement of replisomal components dependent on their

155 In contrast, replacement of saturated fat with mostly refined carbohy

156 This method has been used as a replacement of SDS-PAGE for purity analysis of adeno-ass

157 heterozygosity (LOH) events that lead to the replacement of single, functional tumor suppressor genes

158 The objective was to evaluate replacement of sodium erythorbate with a natural antioxi

159 the albumin bound PTX, represents a superior replacement of Taxol(R) that mitigates the side effects

160 Further optimization through replacement of the amide with a variety of five- and six

161 structural changes to 1 include bioisosteric replacement of the amide with oxadiazole and alpha,alpha

162 hetic collagen is difficult and requires the replacement of the canonical amino acids (4R)-hydroxypro

163 Replacement of the diseased cells with a healthy donor e

164 y gradually switching from FPP to GPP, until replacement of the final alpha-helix, whereupon cyclopro

165 Chronic GVHD is fundamentally caused by replacement of the host's immune system with donor cells

166 nt infection (PJI) usually requires surgical replacement of the infected joint and weeks of antibioti

167 s elegant approach and describe the galvanic replacement of the liquid metal alloy galinstan with Ag

168 Replacement of the LIZ with alanine resulted in dramatic

169 a Monte Carlo simulation framework, partial replacement of the LSL was predicted to result in releas

170 result in chronic inflammation or adipogenic replacement of the myofibers.

171 t chronic muscle inflammation and adipogenic replacement of the myofibers.

172 of noncanonical amino acid mutagenesis, that replacement of the proline residue at position 28 of the

173 Replacement of the transmembrane domain of CD74 or the a

174 rnover throughout life, causing the constant replacement of their synaptic contacts.

175 However, replacement of TM2 by the transmembrane domain of CD4, t

176 2013-2018 began with the synchronized global replacement of trivalent OPV (tOPV) with bivalent OPV (b

177 kinase inhibition, and CRISPR-Cas9-mediated replacement of WT KRAS with a mutant allele sensitized h

178 inine-to-serine change (R764S) in ZF9 and by replacement of ZF11 with two other fingers, yielding 14

179 for 5 wk every 4 mo for 3 y or to daily meal replacements of 1-2 meals for 3 y [regular (RE) group].

180 The effects of amino acid replacements on lipid association of the C-terminal pept

181 ess the effects of symbiont acquisitions and replacements on the shift into novel ecological niches a

182 of intermittent LED compared with daily meal replacements on weight-loss maintenance and number of kn

183 als homozygous for rs532464664 had their hip replacement operation 13.5 years and 4.9 years earlier t

184 patients who underwent primary aortic-valve replacement or mitral-valve replacement with a mechanica

185 vision surgery in patients who had total hip replacement or total knee replacement over the age of 70

186 -y maintenance, additional use of daily meal replacements or intermittent LED resulted in weight-loss

187 who had total hip replacement or total knee replacement over the age of 70 years was about 5% with n

188 n weight-loss maintenance and number of knee replacements over 3 y.The design was a randomized trial

189 resulting from these trans-species enhancer replacements parallel features of the respective donor f

190 However, the transcatheter aortic valve replacement patient presents a unique challenge as many

191 il As and rice yields were measured for soil replacement plots where the soil was exchanged and adjac

192 ent (<2 yr) or old partial lead service line replacements (PLSLRs).

193 for costly integrity monitoring and membrane replacement practices.

194 time experiments to understand the galvanic replacement process.

195 ons used in the solution during the galvanic replacement process.

196 The galvanic replacement reaction is a highly versatile approach for

197 Among patients who underwent aortic-valve replacement, receipt of a biologic prosthesis was associ

198 To prevent serotype replacement, reduce transmission, and limit the emergenc

199 This replacement results in a P*U pair containing only one hy

200 to-noise ratio in likelihood-based molecular replacement searches has been developed to account for t

201 ral Protection in Transcatheter Aortic Valve Replacement [SENTINEL]; NCT02214277).

202 utant receptors with a variety of side-chain replacements still accessed both the ON and OFF signalin

203 TE-defined liver stiffness cutoffs as a test replacement strategy (to replace liver biopsy) in making

204 tudy Pita functions, we have used a boundary replacement strategy by substituting modified DNAs for t

205 Furthermore, CD73 inhibition and enzyme replacement studies showed no change in total kidney ade

206 musculoskeletal admissions, mainly for knee replacement surgeries.

207 ass graft [CABG] surgery and valve repair or replacement surgery, the replacement of multiple valves,

208 h the approval of transcatheter aortic valve replacement (TAVR) for patients with severe symptomatic

209 upport the use of transcatheter aortic valve replacement (TAVR) for the treatment of aortic stenosis

210 Transcatheter aortic valve replacement (TAVR) has become a well-accepted option for

211 g the outcomes of transcatheter aortic valve replacement (TAVR) in diabetic patients are limited by s

212 y and efficacy of transcatheter aortic valve replacement (TAVR) in patients with pure native aortic r

213 Transcatheter aortic valve replacement (TAVR) is standard therapy for patients with

214 mplications after transcatheter aortic valve replacement (TAVR) may be reduced with transcatheter cer

215 on is used during transcatheter aortic valve replacement (TAVR) with limited evidence as to the safet

216 y experience with transcatheter aortic valve replacement (TAVR) within failed bioprosthetic surgical

217 inability to bioengineer full-sized, living replacement teeth.

218 onality was rescued by additional amino acid replacements that differed among poison frog lineages.

219 nterrogated after MRI and required immediate replacement; the device had not been appropriately progr

220 e the potential to enable cell-based insulin replacement therapies (such as human islet or stem cell-

221 Agonist-replacement therapies have been successfully used for tr

222 cient delivery of messenger RNAs for protein replacement therapies offers great promise but remains c

223 The evidence about nicotine replacement therapies was inconclusive (RR: 1.22; 95% CI

224 tion slowed the clinical development of cell replacement therapies.

225 pport (79.4% vs 55.0%; p < 0.001), and renal replacement therapy (48.8% vs 22.1%; p < 0.001).

226 Continuous renal replacement therapy (CRRT) benefits patients with renal

227 e-modified cells is an alternative to enzyme replacement therapy (ERT) and allogeneic HSCT that has s

228 patients, which was not corrected by enzyme replacement therapy (ERT).

229 The need for renal replacement therapy (five [3.2%] and six [3.9%] patients

230 nomes could pose a problem for mitochondrial replacement therapy (MRT).

231 as potential repercussions for mitochondrial replacement therapy (MRT; see description of currently e

232 as associated with a decreased risk of renal replacement therapy (OR, 0.26 [95% CI, 0.11-0.60]).

233 R, 2.38 [95% CI, 1.30-4.35]; I2 = 2%), renal replacement therapy (OR, 1.90 [95% CI, 1.25-2.90]; I2 =

234 h was attenuated in those who received renal replacement therapy (positive fluid balance x renal repl

235 We evaluated the effect of renal replacement therapy (RRT) on serum ammonia level and out

236 ne clearance 0-236mL/min; 29 receiving renal replacement therapy (RRT)) were subjected to population

237 association between exposure to testosterone replacement therapy (TRT) and prostate cancer risk is co

238 s inserted preoperatively, or need for renal replacement therapy at any time postoperatively.

239 Although factor VIII (FVIII) replacement therapy can be lifesaving for patients with

240 nesis inhibitors, can be repurposed for TSP1 replacement therapy for CCMs.

241 s for infertility treatment or mitochondrial replacement therapy for mtDNA disease.

242 dialysis (PD) is a life-saving form of renal replacement therapy for those with end-stage kidney dise

243 omposite primary end point of death or renal-replacement therapy had occurred in 158 of the 344 patie

244 velopment of stem cell technologies for cell replacement therapy has progressed rapidly in recent yea

245 continuous mechanical ventilation and renal replacement therapy in a long-term care hospital who had

246 The main goal of dopamine cell replacement therapy in Parkinson disease (PD) is to prov

247 ment therapy (positive fluid balance x renal replacement therapy interaction (adjusted hazard ratio r

248 atment is liver transplantation, whereas AAT replacement therapy is therapeutic for emphysema.

249 Kidney replacement therapy is used when complications cannot be

250 mortality rate in patients requiring kidney replacement therapy remains approximately 50%.

251 ent composite of death through day 30, renal-replacement therapy through day 30, perioperative myocar

252 Continuous renal replacement therapy using blood flow rate set at 250 mL/

253 be for specific lysosomal disorders (enzyme replacement therapy via intrathecal or intracerebroventr

254 king and treatment characteristics (nicotine replacement therapy vs. other pharmacotherapy; group vs.

255 ath or severe renal failure leading to renal-replacement therapy was lower among those who initially

256 an area of interest since intravenous enzyme replacement therapy was successfully introduced for the

257 The standard treatment is thyroid hormone replacement therapy with levothyroxine.

258 Continuous renal replacement therapy without anticoagulation was more lik

259 tem, or death), and interventions (ie, renal replacement therapy).

260 0% required vasopressors, 17% required renal replacement therapy, and 28% had liver impairment (bilir

261 ormative strategies for vaccination, protein replacement therapy, and genome editing, collectively af

262 , type 2 diabetes and parity, use of hormone replacement therapy, and oral contraceptives in women.

263 , Tyrer-Cuzick risk, smoking, use of hormone replacement therapy, menopausal status, baseline menopau

264 ntaining oral contraceptives (eOC), hormonal replacement therapy, or angiotensin-converting enzyme in

265 scuss available treatments, including enzyme replacement therapy, oral lipid-lowering therapy, stem-c

266 extracorporeal membrane oxygenation or renal replacement therapy, severe preimplant tricuspid regurgi

267 o human female infertility and mitochondrial replacement therapy.

268 and end stage kidney disease requiring renal replacement therapy.

269 influences circuit life in continuous renal replacement therapy.

270 e was >1.2mg/dL or they were receiving renal replacement therapy.

271 ntricular mechanical assist device, or renal replacement therapy.

272 an 10 mL/min/1.73 m2, or initiation of renal replacement therapy.

273 vitro disease modeling and personalized cell replacement therapy.

274 ased use of mechanical ventilation and renal-replacement therapy.

275 rate anticoagulation during continuous renal replacement therapy.

276 nce, however, was attenuated by use of renal replacement therapy.

277 ically ill adults requiring continuous renal replacement therapy.

278 d chimerism and are free from immunoglobulin replacement therapy.

279 40 patients at 1056 hospitals), or total hip replacement (THR) (231774 patients at 1831 hospitals) be

280 l reactive antibody, age, blood group, renal replacement time, prior kidney transplantation, race, ge

281 between diabetes and incidence of total knee replacement (TKR) due to severe KOA in the Singapore Chi

282 a exist regarding transcatheter mitral valve replacement (TMVR) for patients with failed mitral valve

283 More recently, transcatheter mitral valve replacement (TMVR) has emerged as a potential therapeuti

284 -ILS and may serve as a useful supplement or replacement to PCA-ILS for signal isolation from FSCV da

285 r more total hip replacements and total knee replacements to be done in the younger patient group, an

286 ed for molecular investigation; and targeted replacement transgenic mice homozygous for APOE epsilon4

287 These cells undergo cell death and replacement (turnover) throughout life in non-mammalian

288 to a theoretical transcatheter aortic valve replacement valve size.

289 ents who underwent cardiac, orthopedic joint replacement, vascular, colorectal, and hysterectomy proc

290 ay have undergone transcatheter aortic valve replacement, we conducted a subgroup analysis of patient

291 Using pharmacological intervention and ion replacement, we show that inhibition of K(+) transport a

292 ration devices for transfemoral aortic valve replacement were optimized on valve positioning and redu

293 s in modern populations, indicate that later replacements were not wholesale.

294 f untreated wastewater), and existing system replacement, while also considering urban and rural disp

295 By contrast, replacement with 1-palmitoyl-2-oleoyl-phosphatidylserine

296 ary aortic-valve replacement or mitral-valve replacement with a mechanical or biologic prosthesis in

297 emplates results in precise and targeted DNA replacement with as much as approximately 10% efficiency

298 Gly-4941 replacement with Lys resulted in channels having reduced

299 Transfemoral aortic valve replacement with the ES3 and the Lotus were associated w

300 AD first for fertilizer replacement, with AC second, and AC and AD tied for firs