ライフサイエンスコーパス: replica

1 sly split the colonies, creating a patterned replica.

2 ilting, and from deep-etched rotary-shadowed replicas.

3 luation of gingival recession marks on stone replicas.

4 ular architectures to form conductive carbon replicas.

5 scratched into the anterior segments of the replicas.

6 by the reactive conversion into Si or TiO(2) replicas.

7 cy of ordinary replica exchange, using fewer replicas.

8 p, this approach mitigates the need for many replicas.

9 s performed for 226 ns per replica, using 52 replicas.

10 ies into microporous nanocrystalline silicon replicas.

11 self-assembled organic phase into inorganic replicas.

12 ntial growth of both octahedron and catalyst replicas.

13 gate sampling of 15 mus when summed over all replicas, allowing us to explicitly calculate the free-e

14 strate it by applying it to both a synthetic replica and an experimental preparation of a two-dimensi

15 ons of mesoporous silicates, their nonsilica replicas and composites are discussed including the comb

16 The protocol has been set up on paint replicas and successfully tested on two historical sampl

17 NA/RNA oligonucleotides transfer to the PDMS replica, and the DNA oligonucleotides remaining on the m

18 al and code sequences are transferred to the replica, and the zip code remains on the surface of the

19 e four key steps in making a freeze-fracture replica are (i) rapid freezing, (ii) fracturing, (iii) r

20 st function, with a constraint centering the replicas around a driving assignment.

21 ster array are ready to template another RNA replica array.

22 ely 100 microm can be faithfully replicated, replica arrays consisting of several different oligonucl

23 lting ensemble of structures with one or two replicas, as they are under the strong influence of soli

24 duct of the canonical distributions of these replicas at the different temperatures.

25 In this work we use all-atom replica-averaged metadynamics (RAM) simulations with NMR

26 plex using NMR residual dipolar couplings in replica-averaged metadynamics simulations, we observe tw

27 ical shifts used as structural restraints in replica-averaged metadynamics simulations.

28 sing methyl chemical shifts as restraints in replica-averaged molecular dynamics (MD) simulations, wh

29 surface of RNase A using chemical shifts as replica-averaged restraints in molecular dynamics simula

30 hairpin by incorporating NMR measurements as replica-averaged restraints in molecular dynamics simula

31 in (Ca(2+)-CaM) using NMR chemical shifts as replica-averaged structural restraints in molecular dyna

32 milar to the results in FeSe/STO(001), clear replica bands are observed.

33 The observation of replica bands in single-unit-cell FeSe on SrTiO3 (STO)(0

34 , our angle-resolved photoemission data show replica bands separated by 100 meV from the main bands.

35 STO(110) bare surfaces, and observe similar replica bands separated by approximately the same energy

36 orrelated with the signals registered (seven replicas) by means of the electronic nose and the electr

37 molecule, full-functional peroxidase enzyme replicas called "TAML activators".

38 In addition, metallic glass replicas can also be used as moulds for polymers or othe

39 Up to 10 replicas can be prepared from a single master with no de

40 k between telomeric loops shared by template-replica chromatids is conceptualized in terms of homotop

41 (ii) fracturing, (iii) replication and (iv) replica cleaning.

42 placement are consistent with a recent exact replica computation for d = infinity, whereas some obser

43 Using platinum replica electron microscopy (PREM), we have characterize

44 Using platinum replica electron microscopy in combination with electron

45 Using platinum replica electron microscopy in combination with immunogo

46 Using platinum replica electron microscopy, we characterized the cytosk

47 Here, using platinum-replica electron microscopy, we find that the early hour

48 AIS membrane "undercoat' imaged by platinum replica electron microscopy.

49 We introduce a replica exchange (parallel tempering) method in which at

50 constant-pH molecular dynamics with pH-based replica exchange (pH-REX) to gain insight into the struc

51 Replica exchange (RE) is a generalized ensemble simulati

52 ed Born (GB) implicit solvent, combined with replica exchange (REX), might offer an optimal balance b

53 ted molecular dynamics (MD) with Hamiltonian Replica Exchange and calculated binding free energy chan

54 f HP35 folding emerges when the results from replica exchange and conventional molecular dynamics sim

55 cular dynamics trajectories from Hamiltonian replica exchange and targeted molecular dynamics simulat

56 Htt17Q17, and Htt17Q17P11 using Hamiltonian replica exchange combined with well-tempered metadynamic

57 In this work, we postprocess the replica exchange data using our roadmap-based MaxFlux re

58 ries of macrocycle structures generated from replica exchange dynamics to fully sample the conformati

59 ipping was further examined with Hamiltonian replica exchange free energy calculations revealing a st

60 We perform replica exchange MD (REMD) simulations and find that cla

61 ns of conventional MD, as well as 160 ns of replica exchange MD (REMD), with the GLYCAM06 force fiel

62 The biasing potential-replica exchange MD simulations indicated significant di

63 range of urea concentrations, using all-atom Replica exchange MD simulations.

64 namics (MD) simulations, our method combines replica exchange MD with transition path theory (TPT) to

65 We used replica exchange molecular dynamics (MD) simulations to

66 puted by Poisson-Boltzmann (PB) equation and replica exchange molecular dynamics (MD).

67 Replica exchange molecular dynamics (REMD) calculations

68 Replica exchange molecular dynamics (REMD) is a popular

69 ree peptoid sequences using a combination of Replica Exchange Molecular Dynamics (REMD) simulation an

70 ut approximately 3 microsecond long all atom replica exchange molecular dynamics (REMD) simulations f

71 In this work, de novo replica exchange molecular dynamics (REMD) simulations o

72 energy landscape of the T-loop, we performed replica exchange molecular dynamics (REMD) simulations o

73 tion of nuclear magnetic resonance (NMR) and replica exchange molecular dynamics (REMD) simulations t

74 Here, we use replica exchange molecular dynamics (REMD) simulations t

75 lity mass spectrometry (IMS-MS) and all-atom replica exchange molecular dynamics (REMD) simulations.

76 and tetra-acetylated H4 histone tails using Replica Exchange Molecular Dynamics (REMD) simulations.

77 ss spectrometry (IMS-MS) in conjunction with replica exchange molecular dynamics (REMD) to examine th

78 units are examined in explicit solvent using replica exchange molecular dynamics (REMD) which provide

79 btained from extensive folding and unfolding replica exchange molecular dynamics (REX-MD) simulations

80 Replica exchange molecular dynamics and an all-atom impl

81 In this article, we use exhaustive replica exchange molecular dynamics and an implicit solv

82 -resolution model with umbrella sampling and replica exchange molecular dynamics and performed altoge

83 A replica exchange molecular dynamics computational approa

84 To this end, a series of replica exchange molecular dynamics computer simulations

85 ece subdomain HP35, we conducted two sets of replica exchange molecular dynamics for 200 ns each and

86 nal space of the Cro dimer in solution using replica exchange molecular dynamics in explicit solvent.

87 Replica exchange molecular dynamics is used to explore t

88 This umbrella-sampling replica exchange molecular dynamics method performs a re

89 Size-modified PB agrees with replica exchange molecular dynamics much better than non

90 tetraloop hairpin using a serial version of replica exchange molecular dynamics on a distributed com

91 nal landscape is conducted using temperature replica exchange molecular dynamics over three isochores

92 We show that the use of replica exchange molecular dynamics predicts the structu

93 xchange molecular dynamics method performs a replica exchange molecular dynamics simulation along pep

94 Using replica exchange molecular dynamics simulations and an a

95 lected CTFs [Abeta(x-42); x=29-31, 39] using replica exchange molecular dynamics simulations and ion

96 Using replica exchange molecular dynamics simulations and the

97 Our replica exchange molecular dynamics simulations further

98 nal switch via extensive atomically detailed replica exchange molecular dynamics simulations in expli

99 Our NMR experiments and replica exchange molecular dynamics simulations indicate

100 We apply these methods to replica exchange molecular dynamics simulations of a set

101 Extensive replica exchange molecular dynamics simulations of BBL i

102 del parameterization is accomplished through replica exchange molecular dynamics simulations of short

103 and aggregation of the Abeta peptide through replica exchange molecular dynamics simulations of the 1

104 his question using all-atom explicit solvent replica exchange molecular dynamics simulations of three

105 We first performed replica exchange molecular dynamics simulations of wild-

106 We carried out extensive replica exchange molecular dynamics simulations on 1BBL

107 In this work, we perform constant pH replica exchange molecular dynamics simulations on both

108 We performed replica exchange molecular dynamics simulations on the C

109 t membrane model is used in conjunction with replica exchange molecular dynamics simulations to reach

110 ed Born implicit solvent/membrane model with replica exchange molecular dynamics simulations to sampl

111 We employ replica exchange molecular dynamics simulations to study

112 The replica exchange molecular dynamics simulations used an

113 sembly of the KFFE peptide was studied using replica exchange molecular dynamics simulations with a f

114 le of histone tails in the nucleosome, using replica exchange molecular dynamics simulations with an

115 rpose, we have performed extensive atomistic Replica Exchange Molecular Dynamics simulations, elucida

116 lly reproduced to angstrom-level accuracy in replica exchange molecular dynamics simulations, includi

117 lyzed statistically and compared to standard replica exchange molecular dynamics simulations.

118 ss spectrometry experiments and solvent-free replica exchange molecular dynamics simulations.

119 A replica exchange molecular dynamics study of the r(CGUUG

120 ulations on NCBD to date: we use large-scale replica exchange molecular dynamics to explore the unbou

121 By using replica exchange molecular dynamics we carried out exten

122 All-atom explicit solvent model and replica exchange molecular dynamics were used to investi

123 Using replica exchange molecular dynamics with extensive sampl

124 d atom implicit solvent model and exhaustive replica exchange molecular dynamics.

125 ment of assembled structures using reservoir replica exchange molecular dynamics.

126 area implicit solvent model and sampling by replica exchange molecular dynamics.

127 s obtained from reversible folding/unfolding replica exchange molecular-dynamics simulations of Trp-c

128 -angle x-ray scattering, as well as all-atom replica exchange molecular-dynamics simulations, we show

129 s within the mucus layers using an efficient replica exchange Monte Carlo sampling procedure.

130 en coupled with a simple energy function and replica exchange Monte Carlo simulation, our CNF method

131 Replica exchange Monte Carlo simulations using a coarse-

132 lymer lattice model and stochastic sampling (replica exchange Monte Carlo) for canonical ensemble sim

133 This method, known as Hamiltonian Replica Exchange Monte Carlo, outperforms the original M

134 ensemble search method known as Temperature Replica Exchange Monte Carlo.

135 DPs), we first combined implicit solvent and replica exchange sampling to calculate atomistic disorde

136 ational ensemble determined from multiplexed replica exchange simulations at the folding-transition t

137 r methodology involved extensive multiplexed replica exchange simulations of the target proteins with

138 ed in peptide binding, in turn verified with replica exchange simulations performed on a peptide boun

139 sing implicit solvent molecular dynamics and replica exchange simulations, we study the impact of ibu

140 the folding time distribution from all-atom replica exchange simulations.

141 fficients are determined from the short-time replica exchange simulations.

142 chnique called free energy perturbation with replica exchange solute tempering (FEP/REST).

143 cular dynamics method combined with pH-based replica exchange to determine the pK(a) values of titrat

144 The application of GNEIMO with replica exchange to the study of fasciculin conformation

145 By combining Hamiltonian replica exchange with a finite-temperature string method

146 Here, we utilize a recently developed replica exchange with guided annealing enhanced sampling

147 Here we adapted the replica exchange with solute tempering method to sample

148 of H4 tail with/without K16Ac was sampled by replica exchange with solute tempering, and the free ene

149 simulation method, free energy perturbation/replica exchange with solute tempering, to two modificat

150 eve the computational efficiency of ordinary replica exchange, using fewer replicas.

151 is insight, we developed a novel Hamiltonian Replica Exchange-based method "SWISH" (Sampling Water In

152 eneral tool to extract path information from replica exchange.

153 cs simulations, such as umbrella sampling or replica exchange.

154 t solvent molecular dynamics and Hamiltonian replica exchange.

155 ith a hybrid-solvent scheme and the pH-based replica-exchange (REX) protocol are applied to obtain th

156 We test the new method in replica-exchange continuous constant pH molecular dynami

157 Traditional molecular dynamics (MD) and replica-exchange MD (REMD) simulations of the well-chara

158 Replica-exchange MD simulations also support CTT release

159 ndamental problem, an approach combining the replica-exchange method and umbrella sampling (REM-US) w

160 A new, advanced sampling replica-exchange method has been developed to specifical

161 er of the PICK1-BAR domain using multiplexed replica-exchange molecular dynamics (MREMD) and canonica

162 -35) (Abeta 10-35) peptide were probed using replica-exchange molecular dynamics (REMD) simulations i

163 face forces apparatus (SFA) measurements and replica-exchange molecular dynamics (REMD) simulations o

164 We used accurate all-atom replica-exchange molecular dynamics (REMD) simulations t

165 Within atomistic replica-exchange molecular dynamics (REMD), we develop a

166 Extensive samplings of full-atom replica-exchange molecular dynamics and coarse-grained s

167 Using isobaric-isothermal replica-exchange molecular dynamics and the all-atom exp

168 Using our previous replica-exchange molecular dynamics calcium-free simulat

169 Based upon replica-exchange molecular dynamics data, it was found t

170 NMR spectroscopy and replica-exchange molecular dynamics indicate that introd

171 55)) in a membrane environment determined by replica-exchange molecular dynamics simulation.

172 Here we use all-atom replica-exchange molecular dynamics simulations in gener

173 Replica-exchange molecular dynamics simulations of a hig

174 Here, we have performed extensive atomistic replica-exchange molecular dynamics simulations of the s

175 Replica-exchange molecular dynamics simulations show tha

176 ferences, we performed microsecond timescale replica-exchange molecular dynamics simulations to sampl

177 Here, we use replica-exchange molecular dynamics simulations with an

178 by coarse-grained canonical and multiplexed replica-exchange molecular dynamics simulations with the

179 H3 N-terminal tail by molecular dynamics and replica-exchange molecular dynamics simulations.

180 loid beta-protein (Abeta) is investigated by replica-exchange molecular dynamics simulations.

181 ocess, loop dynamics were investigated using replica-exchange molecular dynamics that yielded conform

182 With the use of a coarse-grained model with replica-exchange molecular dynamics, a longer timescale

183 oism, differential scanning calorimetry, and replica-exchange molecular dynamics.

184 oism, differential scanning calorimetry, and replica-exchange molecular dynamics.

185 ive cellulases with free energy perturbation/replica-exchange molecular dynamics.

186 We performed extensive replica-exchange molecular-dynamics simulations on Ala(3

187 ynamics of a beta-hairpin, using large-scale replica-exchange molecular-dynamics simulations with an

188 We performed replica-exchange molecular-dynamics simulations with umb

189 it (GB/SA) model of solvation, combined with replica-exchange molecular-dynamics simulations.

190 For validation, extensive replica-exchange Monte Carlo simulations are performed o

191 placements in the crystal unit-cells through replica-exchange Monte Carlo simulations, with the phasi

192 rmational families determined by multiplexed replica-exchange simulations, from the 10th Community Wi

193 Here, we describe a "replica-extraction-transfer" (REX) technique that overco

194 ted into electronically transparent graphene replicas, fabricated using chemical vapor deposition of

195 We develop a full microscopic replica field theory of the dynamical transition in glas

196 cuum-deposition of platinum-carbon to make a replica for examination in the transmission electron mic

197 from the tracer experiments conducted in the replica fracture illustrating the large effect that matr

198 RS2-GFP tracer experiments conducted in the replica fracture show that increasing specific discharge

199 E. coli RS2-GFP transport through the epoxy replica fracture, which capture for the first time the p

200 e analysis with different methodology of six replica from the same sample showed lowest variability (

201 ew species sequences using all the available replicas from model species.

202 erived aliphatic hydrocarbons, the petroleum-replica fuels, have emerged as promising alternatives to

203 The resulting gold replica has a feature size that is two orders of magnitu

204 lated pKa values based on 10-ns sampling per replica have the average absolute and root-mean-square e

205 Electron microscopy renders these graphene replicas highly transparent, revealing previously unobse

206 re we report on production of such petroleum-replica hydrocarbons in Escherichia coli.

207 nvestigate this, we combined freeze-fracture replica immunogold labeling of Cav2.1 channels, local [C

208 xin36 immunofluorescence and freeze-fracture replica immunogold labeling revealed a large variability

209 Freeze-fracture replica immunogold labeling revealed the presence of the

210 microscopy, and grid-mapped freeze-fracture replica immunogold labeling, 10 close appositions reveal

211 Using replica immunogold labeling, here we show that all CA1 P

212 EM replica immunogold labeling, however, demonstrated only

213 ortical activity to control a mechanized arm replica in a self-feeding task.

214 and occurs autonomously, with the number of replicas increasing exponentially over time without the

215 oint distribution of the composite system of replicas is the normalized sum of the symmetrized produc

216 nuclei by a highly sensitive freeze-fracture replica labeling technique.

217 to create arrays of individually addressable replica microbial cultures.

218 A replica molded polydimethylsiloxane (PDMS) microfluidic

219 dual functions of barbs were reproduced with replica molded synthetic polyurethane quills.

220 This method uses replica-molded transparent polymer parts to create minia

221 ion polymers, and can be used as masters for replica molding

222 hylene glycol) (PEG) microparticles based on replica molding (RM) for highly uniform and robust nucle

223 in thin rubber sheets were fabricated using replica molding and were subjected to stretching, foldin

224 ns on gold-coated and glass substrates; (ii) replica molding for fabrication of microfluidic devices

225 During the replica molding process, a uniaxial force is applied to

226 tolithography and requires no silicon wafer, replica molding, and plasma bonding like microfluidic de

227 Here, we used replica molecular-dynamics simulations and network theor

228 The platform was fabricated using replica moulding technology in PDMS patterned by high-as

229 We applied the single-replica multiple-state transition-interface sampling met

230 ed as masters for the fabrication of inverse replica nanochannels in a special formulation of PDMS.

231 im here was to conduct a multicentre, 1 year replica of a clinical trial in patients with one of four

232 ve infection, a retrovirus must insert a DNA replica of its genome into host cell chromosomal DNA.

233 ntative of the experimental data after 60 ns/replica of simulation time.

234 atural rock fracture and a transparent epoxy replica of that same fracture.

235 ith hydrofluoric acid yields a free-standing replica of the internal and external native frustule mor

236 sults strongly suggest that BT cells carry a replica of the motor command.

237 TP53 gene sequences has offered a humanized replica of the TP53 gene in a murine genetic environment

238 A gold-coated replica of this surface elicited an optical response tha

239 tants with lower adaptabilities) to multiple replicas of a regimen of positive selection and then det

240 components and with functionalized polymeric replicas of biofilm microstructure.

241 Eight replicas of cheese were produced and a total of 48 chees

242 lysis to form electrically conductive carbon replicas of complete organisms.

243 hain reaction (PCR) is performed to transfer replicas of desired STR targets from the single-cell gen

244 and maxillary master casts, and eight stone replicas of each master cast were produced.

245 that brain systems create and use inhibitory replicas of excitatory representations for important cog

246 rotextured films, 3D shapes, and metal oxide replicas of natural biotextures.

247 it remains a challenge to create artificial replicas of natural photonic structures.

248 be restabilized via formation of inhibitory replicas of newly formed excitatory connections.

249 espite the overall fitness differences, some replicas of one mutant strain at passage 50 showed fitne

250 uch-based responses, we used both biomimetic replicas of petal surfaces and isogenic Antirrhinum line

251 iffractive optical effects produced by epoxy replicas of petals with folded cuticles persist and indu

252 Here, we report on pyritized replicas of the iconic autotrophic Gunflintia-Huroniospo

253 zed in vitro generating nanopatterned silica replicas of the microring structures.

254 unction given by a sum of a finite number of replicas of the original cost function, with a constrain

255 eal that regenerated limbs are high fidelity replicas of the originals even after repeated amputation

256 TAML activators are exceptional functional replicas of the peroxidases and cytochrome P450 oxidizin

257 models were assessed by simulating multiple replicas of the phase III studies.

258 Freeze-fracture replicas of the PM of Orai1-transfected cells showed ext

259 The idea is to run several replicas of the system in parallel at different temperat

260 pic colloid particles fabricated as negative replicas of the target cells which involve templating of

261 d with a set of organic molecules, for which replicas of their (1)H NMR spectra were generated.

262 are (preprocessing, simultaneous analysis of replicas, of different conditions, ROI calculation, mult

263 erature oxidative calcination to form silica replicas or reductive pyrolysis to form electrically con

264 EBMetaD does not require multiple simulation replicas or the introduction of Lagrange multipliers, an

265 lecular dynamics with extensive sampling (16 replicas per sequence and 600 ns per replica), we invest

266 The silicon replicas possessed a high specific surface area (>500 m(

267 electrodeposited gold nanowires in a master-replica process and characterized with scanning electron

268 double LPNE fabrication method, this master-replica process was also used to create a large two-dime

269 model approach assimilates information from replica QMM assays, improving reliability and inter-assa

270 nected pore space, ordered mesoporous carbon replicas serve as conceptually attractive materials for

271 observables, the ensembles of more than two replicas show larger orientational variations similar to

272 Multiple replica simulations of ATP-, ADP-, and inhibitor-bound s

273 nucleic acid backbone that are added in the replica simulations to promote transitions of the most c

274 lm or agar culture; the metabolites are then replica "stamped" onto the NIMS surface.

275 are able to show the unbiased folding of all replicas starting from extended conformations.

276 us HCl followed by 5% H2O2 yielded a titania replica that retained the morphology of the parent HKUST

277 biofilms that consume the embryo but form a replica that retains cell organization and morphology, a

278 For all replicas, the 3D optical method showed small standard de

279 basic parameters of RE (e.g., the number of replicas, the RE rate, and the temperature spacing) all

280 pling theory, density functional theory, and replica theory, all miss this crucial element.

281 By bringing together results from replica theory, cavity reconstruction, void percolation,

282 s (REMD) simulations on the microseconds-per-replica timescale are used to characterize the structura

283 th transmission electron microscopy of metal replicas to locate proteins on the landscape of the cell

284 on the order of hundreds of nanoseconds-per-replica toward ensembles that yield good agreement with

285 uperresolution light microscopy and platinum replica transmission electron microscopy (TEM) to determ

286 osites (CSCs) and their conversion to silica replicas using mammalian cells as scaffolds to direct co

287 forms a hairpin is performed for 226 ns per replica, using 52 replicas.

288 pumping reveal energy-gain and -loss Floquet replica valence bands that appear instantaneously in con

289 Each replica was scanned 10 times with a 3D optical system, a

290 The PDMS replica was then oxygen plasma-bonded to a glass substra

291 rfaces or on flexible, inexpensive polymeric replicas was discovered.

292 the original repetitive waveforms into fewer replica waveforms.

293 ing (16 replicas per sequence and 600 ns per replica), we investigate the structure of the monomeric

294 Microporous titania replicas were made from the MOF template HKUST-1 by dehy

295 The silicon replicas were photoluminescent, and exhibited rapid chan

296 The modified replicas were then scanned 10 times, and 3D datasets wer

297 n in electron micrographs of freeze-fracture replicas with periodicities of 16 and 12 nm, respectivel

298 These include scaled replicas with sub-100-nm-level control of feature sizes

299 (III)-TAML activators as miniaturized enzyme replicas with the potential to greatly expand the techno

300 On average, one of two replicas yielded positive growth with 2.5% NaOCl and one