ライフサイエンスコーパス: replicate

1 tive large T (LT) phosphoprotein helicase to replicate.

2 only forms trimers and tetramers that do not replicate.

3 ssigned to the most probable isoform in each replicate.

4 and that permitted ICP0-deficient mutants to replicate.

5 (Mimiviridae) and hijack their machinery to replicate.

6 ion cohort, and 2 of these associations were replicated.

7 methylation at the CBL signaling pathway was replicated.

8 their genomes are completely and accurately replicated.

9 iles; and unifies the processing of multiple replicates.

10 but changes were not consistent between the replicates.

11 dent UK cohort (171 NSCLP, 177 controls), we replicated 4 out of 11 tested MVPs.

12 19 individuals, we found 38 new variants and replicated 5 known variants associating with IgA, IgG or

13 Eleven of them replicate (5% FDR) in five independent longevity studies

14 which creators provide everything needed to replicate a given project online, as well as providing e

15 eep trait (near PATJ (INADL) and HCRTR2) and replicate a locus associated with sleep duration (at PAX

16 These data also replicated a linear inequality-ambivalence relationship.

17 We replicated a spectrum of known biases, as measured by th

18 stem of DNA origami rafts that exponentially replicates a seed pattern, doubling the copies in each d

19 tice by identifying regulatory regions which replicate across samples and connect them to the genes t

20 ted differential methylation at 83 CpGs that replicated across cohorts; BMI-related differential meth

21 stle, Cirsium vulgare, in a field experiment replicated across eight sites in eastern Nebraska.

22 ent molecular players in OA progression that replicated across independent datasets and that have tra

23 in which small effects persist and have been replicated across populations and across time.

24 The model replicates activity in the unmyelinated axon of the crus

25 se sites are a sanctuary and a reservoir for replicating AIDS viruses.

26 We convincingly replicate all novel loci via multivariate tests.

27 rs1531554, OR = 0.68, P = 2.9 x 10(-8)) was replicated among females (1-tailed P = 0.002), as well a

28 Results from experimental replicate analysis (n = 5) of 1:1, 2:1, and 1:2 (12)C-/(

29 In the replicate analysis of a 1:1 (12)C-/(13)C-labeled human u

30 es must suppress host antiviral responses to replicate and spread between hosts.

31 tleneck selects for viruses that are able to replicate and spread efficiently in the face of a potent

32 The most replicated and relevant genetic variants include polymor

33 These were replicated and validated.

34 uts a list of peaks reliably observed across replicates and facilitates data handling by preprocessin

35 Reproducibility between iCLIP replicates and single-cell RNA-seq clustering are both i

36 rophozoites, which are the actively feeding, replicating and mobile form of FLA.

37 thienopyrimidine derivative that kills both replicating and nonreplicating bacilli.

38 their hosts and vectors in order to infect, replicate, and disseminate; hence, viruses can be consid

39 l templates and free technologies to borrow, replicate, and employ for a range of applications.

40 re to gain from treatment, we were unable to replicate any genotype-treatment interactions after adju

41 Three distinct influenza viral groups (VGs) replicating as a "swarm" of viruses were identified (swi

42 At P < 0.05, we replicated associations with 10 of 11 variants previousl

43 Eukaryotic DNA replicates asynchronously, with discrete genomic loci re

44 t a template for how a similar course can be replicated at other institutions and provide pedagogical

45 ofovir arm were 2-fold less infectious, they replicated at rates similar to those of viruses from the

46 surface-attached communities of slow- or non-replicating bacteria encased within a protective extrace

47 rphological and behavioral convergence, with replicate beetle lineages following a predictable phenot

48 erformed the orbitofrontal cortex, a finding replicated both in simultaneously and nonsimultaneously

49 ota at the family level in each experimental replicate, but changes were not consistent between the r

50 ting prion disease based on producing a self-replicating, but innocuous PrP(Sc)-like form, termed ant

51 of specialization and structure that is not replicated by a model wherein cells receive random feedf

52 ion with an NAD(H) insensitive CtBP, and are replicated by a synthetic peptide that inhibits CtBP dim

53 This phenomenon was replicated by exogenous preexposure to the amino acid D-

54 tinel SNPs and case-control status have been replicated by genome-wide association studies.

55 otein (WRN) suppresses the loss of telomeres replicated by lagging-strand synthesis by a yet to be de

56 induced abnormalities in Gnal(+/-) mice were replicated by oxotremorine infusion into the striatum, b

57 me of influenza A viruses is transcribed and replicated by the viral RNA-dependent RNA polymerase, co

58 The eukaryotic genome is primarily replicated by two DNA polymerases, Pol epsilon and Pol d

59 ral outcomes, including susceptibility, were replicated by two independent laboratories.

60 c DNA isolated from HBV-related HCCs and HBV replicating cells, and examined DNA methylation of a CpG

61 ethylation of these CpGs was observed in HBV replicating cells.

62 nts whose tumours contain a high fraction of replicating cells.

63 the repair complex for oxidized bases in non-replicating chromatin, and allow repair when oxidized ba

64 full 100 nucleotides of (T2AG3)n lost from replicated chromosome ends as a single elongation event.

65 The resulting networks replicate complex dynamics previously observed in animal

66 DNA necessitates that the leading strand is replicated continuously whereas the lagging strand is re

67 develop new synthetic network models able to replicate controllability properties of real-world netwo

68 xpression of a reporter gene relative to non-replicating controls.

69 During mitosis, cells must segregate the replicated copies of their genome to their daughter cell

70 or of several human DNA polymerases that can replicate damaged DNA.

71 al nucleoside triphosphates and uses them to replicate DNA containing the UBP.

72 elomere-specific single-molecule analysis of replicated DNA technique, we found that depletion of FAN

73 er 2013 through October 2014, a prospective, replicate dosing, partially blinded, randomized, 3-treat

74 d climates of the Cryogenian have never been replicated during the Phanerozoic despite similar, and s

75 s asynchronously, with discrete genomic loci replicating during different stages of S phase.

76 e prominent extensions of protein IX and can replicate efficiently in a phylogenetically diverse rang

77 ia reverse genetics resulted in viruses that replicated efficiently but exhibited less cytotoxicity a

78 lular arrival times and vie for resources to replicate, enabling the interplay during different devel

79 many well-characterized animal DNA viruses, replicate entirely within the cytoplasm of animal cells,

80 significant, independent signals, including replicating evidence for association at eight novel low-

81 scored had no disagreements across the three replicates (except one locus in a wolf sample).

82 sual group of organisms that have evolved to replicate exclusively within the cytoplasm or vacuole of

83 Obligate intracellular bacteria replicate exclusively within the interior of living cell

84 s GxE studies have faced (e.g., difficulties replicating findings and high false discovery rates).

85 This study aimed to replicate five of these suggestive loci in a Han Chinese

86 tly associated (P < 1e-07) with eGFR/CKD and replicated, five also associate with renal fibrosis in b

87 Statistical significance was replicated for BIRC2 (p = 0.041) and NOD2 (p = 0.045) in

88 bility or chromosomal uptake of autonomously replicating foreign mobile genetic elements.

89 To do so, we processed three C1 replicates from three human induced pluripotent stem cel

90 the absence of RAD51, the unprotected newly replicated genome is degraded by the exonuclease activit

91 Our data suggest that each replicated genome will have an average of 2-3 mutations

92 peutic implications for T2D, we analyzed and replicated genome-wide protein coding variation in a tot

93 ed chromatin structure in all regions of the replicating genome.

94 tial enzymes that faithfully and efficiently replicate genomic information.1-3 The mechanism of nucle

95 is heavily and specifically loaded into late replicating genomic regions and is then redistributed du

96 antiretroviral therapy among patients with a replicating HDV infection in the Swiss HIV Cohort Study.

97 viduals even at the expense of the number of replicate hiPSC clones.

98 of these cells into complex structures that replicate human kidney function.

99 ted with UC in only this population; we also replicated IBD, CD, and UC loci identified in European p

100 Four types of replicate implants were used in this study: 1) acellular

101 ifically addressing how they do, and/or did, replicate.IMPORTANCE Endogenous retroviruses are relics

102 Obligate intracellular Chlamydia trachomatis replicate in a membrane-bound vacuole called inclusion,

103 the virus were identified and were found to replicate in an archaeal host species closely related to

104 hampered by the fact that MERS-CoV does not replicate in commonly available mouse strains.

105 In order to understand how these viruses replicate in human cells, we previously conducted genome

106 that influences the ability of poxviruses to replicate in human cells.

107 In a separate study, we replicate in humans (154 healthy controls) using resting

108 ce variants of genome-wide significance that replicate in independent data sets.

109 of oxygen in the laboratory, it was able to replicate in macrophages and colonize the spleens, but n

110 mastigotes lacking one SODA allele failed to replicate in macrophages and were severely attenuated in

111 This HSV-1 mutant was able to replicate in noncomplementing cells, even at a low multi

112 es derived from a marine plant endophyte can replicate in plant cells.

113 are infectious intracellular pathogens that replicate in professional and non-professional phagocyti

114 ility to cause disease in swine, efficiently replicate in swine macrophage and that is fluorescently

115 unin virus vaccine (Candid#1) preferentially replicate in tumour cells in a variety of murine and hum

116 ntiviral state in many cell types, HIV-1 can replicate in vivo via mechanisms that have remained uncl

117 I) in 1000 unrelated Caucasian subjects, and replicated in 2283 unrelated Caucasians subjects.

118 The association is replicated in 44 independent cases and 1902 controls.

119 s characteristic of meat or fish intake were replicated in 50 EPIC subjects for whom a 24-h urine sam

120 Findings were replicated in a case-control sample nested within the pr

121 Findings were replicated in a cohort comprising 143 individuals.

122 The SNP association was also replicated in a depressive symptom sample that shares so

123 epigenetic effect on cortical thickness was replicated in a sample comprising 596 participants with

124 This pattern of associations was replicated in a second study.

125 orphisms (SNPs), but many SNPs have not been replicated in a separate cohort.

126 Significant associations were replicated in a South African familial sample.

127 an increased risk of developing obesity was replicated in an independent CHS sample.

128 Results were replicated in an independent cohort obtained from a popu

129 ltidisciplinary center, and the analysis was replicated in an independent cohort of 116 patients with

130 The latter association has been replicated in an independent cohort of 121 independent s

131 A repair, and inflammatory pathways could be replicated in an independent cohort study of donor-match

132 omical and neurochemical specificity and are replicated in an independent cohort.

133 The association is replicated in an independent data set of 369 autopsies.

134 The association with 4 of these replicated in an independent GWAS: B4GALT3, USMG5, P2RY1

135 The study was replicated in an independent Han Chinese population comp

136 Association analyses were replicated in an independent sample group derived from f

137 This association was further replicated in another sample of 399 German CP cases (dis

138 nprecedented MOF modularity, which cannot be replicated in any other type of materials.

139 pe-phenotype associations were significantly replicated in AREDS.

140 discovery rate <0.05), of which seven genes replicated in both directionality and at nominal signifi

141 lts obtained following in vivo treatment are replicated in brain slice cultures from 3xTg-AD mice.

142 This 3-cluster solution was replicated in CO-MED and was similar for the HAM-D scale

143 uced dG-AP cross-link-containing plasmid was replicated in cultured human cells.

144 d continuously whereas the lagging strand is replicated in discrete segments known as Okazaki fragmen

145 This finding will need to be replicated in future studies.

146 indings should be interpreted cautiously and replicated in future studies.

147 19, P=1.91 x 10(-35) for drinks/week), which replicated in Hispanic/Latinos (OR=0.72, P=4.35 x 10(-7)

148 However, NY/108 virus replicated in human bronchial epithelial cells with an i

149 Twenty-seven (46%) of these loci could be replicated in independent cohorts, underlining the role

150 This association was replicated in independent participants treated with chlo

151 ong females (1-tailed P = 0.002), as well as replicated in meta-analysis of both sexes (1-tailed P =

152 unotherapy with checkpoint inhibitors is not replicated in most cases of colorectal cancer; therefore

153 an individual's disease prognosis have been replicated in multiple cohorts: baseline lesion size, le

154 This finding has been replicated in normally grown sheep fetuses following a 7

155 is an important finding that will have to be replicated in other cohorts.

156 This analysis should be replicated in other locations to more fully describe fin

157 IgE in these preclinical experiments can be replicated in patients.

158 at P<5.0 x 10(-6) Of these, rs9980 at NFAT5 replicated in stage 2 meta-analysis (P=3.1 x 10(-5)), wi

159 If these results can be replicated in Symbiodinium cells in hospite, they could

160 The original Webb and Tierney results were replicated in terms of lung/body weight ratio (45/0 > 45

161 Findings replicated in the Dallas Health Study were similar for t

162 This association was not replicated in the inCHIANTI population.

163 ere associated with microbiome diversity and replicated in the independent sample.

164 Results were replicated in the laboratory via anaerobic selenate-redu

165 roscopic plasmonic coupling between AuNPs is replicated in the macroscopic, centimeter-scale films.

166 ic infection with Escherichia coli K1 can be replicated in the neonatal rat.

167 These effects were replicated in the SARP-1 + 2 multivariable model.

168 ngle-SNP associations within this block were replicated in the UK-Ireland group of the most recent re

169 neuroblastoma cells in vitro This effect was replicated in vivo, where Ifit2 knockout mice displayed

170 replication of loci that are normally under-replicated in wild-type tissues.

171 cilitates data handling by preprocessing all replicates in a single step.

172 ytic herpes simplex virus (oHSV) selectively replicates in cancer cells while inducing anti-tumor imm

173 from which infectious virus was rescued that replicates in human and mosquito cells with growth kinet

174 We found that ZIKV infects and replicates in monocytes and macrophages, which results i

175 inant phenotyping system and extensive assay replicates in two types of cell cultures.

176 efense mechanism targeting diverse pathogens replicating in cytosolic membrane structures.

177 and less transcriptionally active chromatin replicating in mid S phase.

178 DNA viruses replicating in the nucleus challenge the resident genome

179 al latency, in which a virus genome does not replicate independently of the host cell genome and prod

180 =0.995), and relative standard deviation for replicate injections lower than 5%.

181 n hosts, differentiate into amastigotes, and replicate inside macrophages.

182 is is essential for M. tuberculosis (Mtb) to replicate intracellularly while protecting it from antib

183 Leishmania replicates intracellularly in macrophages, a process tha

184 which increases the speed and variability of replicated invasions: after 10 generations of range expa

185 Improved confidence in data and the use of replicates is particularly important where strategic dec

186 Replicating Lgr5(+) stem cells and quiescent Bmi1(+) cel

187 es in 21 additional peanut allergic subjects replicate major findings.

188 ved Australia, speaking to the extraordinary replicate mammalian communities found there.

189 ection and evolution of multi-component self-replicating materials in the nanoscopic-to-microscopic s

190 etween the multivariate distributions of two replicates, measured in different batches.

191 deviations were 3.67% and 2.89% for the five replicate measurements of 14 and 35microgL(-1) Se(IV), r

192 The replicated methylation sites are heritable (h(2) > 30%)

193 The analysis of replicating mtDNA molecules provided in vivo evidence in

194 y (MMN) generation are among the most widely replicated neurophysiological abnormalities in schizophr

195 n factor IIH in ATR kinase activation in non-replicating, non-cycling cells.

196 The two replicating NYVAC-C-KC vectors induced enhanced and simi

197 This replicated observation probability was highly significan

198 All viruses with positive-sense RNA genomes replicate on membranous structures in the cytoplasm call

199 , an identical cooling/heating procedure was replicated on a small piece of fat harvested from the sa

200 fold, number of gRNAs per gene and number of replicates on screen performance.

201 amplification of the HBoV1 genome, and HBoV1 replicates only in terminally differentiated, nondividin

202 dermal dendritic cells, yet the virus fully replicates only in the latter.

203 ome provide evidence for a gradient of early replicating, open chromatin that transitions gradually t

204 We then sought to replicate our findings in an independent sample (n = 198

205 e EEG over right occipito-temporal channels, replicating our previous findings.

206 h a mean value of 18.5 neonates produced per replicate over a 21 day chronic exposure to 0.04% FPW, w

207 gene variants (pQTLs) in a German cohort and replicate over half of them in an Arab and Asian cohort.

208 ay be limited by the inability to accurately replicate pathophysiologic interactions of GBM cells wit

209 runs, ensuring comparable magnitudes across replicates, peak alignment, and the use of an adaptive m

210 normoxic conditions but is critical for non-replicating persistence of mycobacteria.

211 A naturally colonised, replicated pond system was used to show how seasonal cha

212 leading to enhanced variance in speed among replicate population expansions.

213 Replicate populations of the filamentous fungus Trichode

214 ity affects the evolution of sex by adapting replicate populations to various environments that diffe

215 ale fertility-impairing mtDNA haplotype into replicated populations of Drosophila melanogaster causes

216 to match a reported error, we are unable to replicate post-FISP production gains.

217 Here we developed novel replicating poxvirus NYVAC-based HIV/AIDS vaccine candid

218 Fifty-five of the replicated pQTLs are located in trans.

219 l (rs189679427 between GOT2 and APOOP5), and replicated previous associations of a splice variant in

220 ian differences in physiological parameters, replicating previous physiological findings.

221 In the current study, we attempted to replicate previously published associations between sing

222 ethnic (overall) meta-analysis and we do not replicate previously reported associations.

223 Consequently, replicating primary cells steadily accrue macroH2A1.2 at

224 the lack of screening models that faithfully replicate prion diseases and the lack of rapid, sensitiv

225 Furthermore, iPSC-derived astrocytes can replicate prions associated with the major sporadic CJD

226 , LCE3B and LCE3C (LCE3B/C-del), is a widely-replicated psoriasis risk factor that interacts with the

227 attern of genome rearrangements in the newly replicated region behind the stalled fork, which primari

228 cation without cell division, and the latest replicating regions occasionally fail to complete endore

229 infection when virus was no longer actively replicating resulted in a pronounced reduction in lesion

230 logical pathways, while 91% are expressed in replicating schizonts.

231 red Report that described how we intended to replicate selected experiments from the paper "BET bromo

232 red Report that described how we intended to replicate selected experiments from the paper "Coadminis

233 red Report that described how we intended to replicate selected experiments from the paper "Discovery

234 ed Report, that described how we intended to replicate selected experiments from the paper "Inhibitio

235 ed Report, that described how we intended to replicate selected experiments from the paper "The commo

236 Although it is known that Toxoplasma replicates slowly within intracellular cysts demarcated

237 d explain the association with the most well-replicated SNP (rs964184) for triglycerides identified b

238 the endogenous Leishmania RNA virus 1 (LRV1) replicating stably within some parasite species has been

239 tious agents that consist of misfolded, self-replicating states of a sialoglycoprotein called the pri

240 Replicating strains were consistent with donor transmiss

241 ithin the variability observed in controlled replicate studies and are highly correlated with measure

242 nds, while embryonic stem cells continuously replicate, suggesting profoundly different regulatory me

243 then be translated to conditions that permit replicating systems to overcome the fundamental limits i

244 Replicated T2D locations were tested for evidence of bei

245 ds are essential for the protection of newly replicated telomeres.

246 ], minor allele frequency=0.018) was used to replicate the association with baseline CK measures.

247 synthesis (TLS), specialized DNA polymerases replicate the damaged DNA, allowing stringent DNA synthe

248 directly reflect ultradian sleep cycles and replicate the dynamics of laboratory sleep parameters.

249 ventual goal of nanolattice design may be to replicate the intricate hierarchies and functionalities

250 Moreover, the model allowed us to replicate the kinetics of junctional conductance under d

251 tion methods, assessed in this study, do not replicate the observed dependency on the relative positi

252 computational analyses, our findings broadly replicate the pattern reported after selective lesions i

253 We replicated the ADO-EGR2, IRF8, and CEBPB-PTPN1 loci by g

254 cating bats (three females and one male) and replicated the general trends reported in other species

255 In zebrafish, tbc1d23 morphants replicated the human phenotype showing hindbrain volume

256 We replicated the interaction of a variant in NOD2 with cur

257 Whereas we replicated the notion of hyperaltruism (i.e., the willin

258 will be accelerated by an animal model that replicates the phenotype of human CTEPH.

259 histone deacetylase (HDAC)-dependent manner, replicating the expression of their respective endogenou

260 A second team focused on replicating the key claim of an interaction between geno

261 n-looking approaches which cannot adequately replicate their 3D structure.

262 All plants and animals must replicate their DNA, using a regulated process to ensure

263 analysis to identify age-methylated CpGs and replicated them in two independent Danish cohorts.

264 icant number of synthetic systems capable of replicating themselves or entities that are complementar

265 A model based on structural data can replicate these changes, and indicates that splicing may

266 To replicate these findings and determine whether they coul

267 Further study is needed to replicate these findings and identify potential mechanis

268 Further research is needed to replicate these findings, determine their clinical signi

269 Future studies should attempt to replicate these results in other cohorts and evaluate th

270 In Experiment 1 we replicated these animal findings in humans (US-expectanc

271 tudies in adult-onset primary CNS tumors and replicated these in survivors of childhood cancer with a

272 Attempts to replicate this feat in artificial systems almost invaria

273 The first aim of the present study was to replicate this finding using alternative methods for mea

274 sessment of transgenic (Tg) mouse lines that replicate this process is critical for establishing the

275 Simulations replicated this evolution only when value functions, whi

276 ciency conceals the inherent difficulties in replicating this contra-thermodynamic transformation in

277 If replicated, this community and clinic accessible therapy

278 troviral elements have lost their ability to replicate, those whose insertion took place more recentl

279 The study demonstrated that EBOV and MARV replicate to similar levels in all tested cell lines, in

280 We show that NiV-B replicated to high titers in human lung grafts and cause

281 in intradermally inoculated ears, vDeltaK1L replicated to levels nearly identical to those of VACV,

282 VP4-R446G)) produced less symptomatology and replicated to lower titers both in vivo and in vitro tha

283 We previously showed that NiV replicates to high titers in human lung grafts in NOD-SC

284 The virus replicates to high titers in the liver of these animals

285 re on ecosystem properties, here we evaluate replicate treeline ecotones in seven temperate regions o

286 HBV replicated unrestricted in HUHEP mice resulting in high

287 ll-animal models that have been developed to replicate various aspects of disease associated with ZIK

288 Replicated VDR-BVs associated with these disorders could

289 We have also observed that newly replicated viral DNA is not associated with cellular his

290 o identify where mutations were tolerated in replicating viruses.

291 rmation of NOI), (ii) the reproducibility of replicates was enhanced compared to the triiodide-based

292 ng amino acid changes in the HA stalk domain replicated well in vitro, and viruses incorporating two

293 he virus is surprisingly inefficient, barely replicating well enough to spread to neighboring cells i

294 mm, and the coefficients of variation for 5 replicates were <11%.

295 fSPZ) Vaccine is a metabolically active, non-replicating, whole malaria sporozoite vaccine that has b

296 Using replicate wild populations with differing levels of sexu

297 typhi (R. typhi(GFPuv)) bacteria are viable, replicate with kinetics similar to those of wild-type R.

298 ome-wide significance, although they did not replicate with published GWA analyses of normal-range IQ

299 d from this yeast-assembled genome, KOS(YA), replicated with kinetics similar to wild-type virus.

300 ca are invasive intracellular pathogens that replicate within a membrane-bound compartment inside inf