ライフサイエンスコーパス: replication competence

1 , although other mutations were required for replication competence.

2 4V, thereby restoring both Rb regulation and replication competence.

3 maintenance-2 (MCM2) protein was tested for replication competence.

4 thogenic lesions correlated with a defect in replication competence.

5 complex [3], which is necessary to establish replication competence.

6 nt variants was constructed and analyzed for replication competence.

7 eam effector of lamina assembly in promoting replication competence.

8 g p53, retinoblastoma, and p107, yet retains replication competence.

9 nd to block replicated DNA from re-acquiring replication competence [2].

10 To assess the in vivo replication competence, all viruses contained a stop cod

11 tance mutations resulted in moderate loss of replication competence, although several (V36A/L/M, R109

12 h a prototype human MERS-CoV to assess virus replication competence and cell tropism in ex-vivo cultu

13 ro-activated cells, we also investigated the replication competence and pathogenic potential of these

14 y to examine age-associated human islet cell replication competence and reveal mechanisms underlying

15 4E10 recognition sequences in gp41 retained replication competence and were used for neutralization

16 ichromosome maintenance (MCM)-2, a marker of replication competence, and mounted in medium containing

17 While proviral replication competence appeared to be associated with th

18 (i) the YPDL L domain of p9 is required for replication competence (assembly and infectivity) in equ

19 c factors contribute to the establishment of replication competence at OriP.

20 capability; then it finally acquires optimal replication competence by additional mutations when the

21 Replication competence can be restored in these nuclei,

22 Replication competence could be rescued by reinsertion o

23 How oocytes lose and regain replication competence during meiosis are important ques

24 that limit the establishment of the oocyte's replication competence during meiosis.

25 stem of the 3'SL are primary determinants of replication competence for flavivirus genomes.

26 of individual genes necessary for conferring replication competence in a heterologous host is importa

27 y to bind retinoblastoma but retaining viral replication competence in cancer cells with a defective

28 e in the central nervous system but maintain replication competence in dividing cell populations, suc

29 horylation also decreased cell-free SV40 DNA replication competence in extracts of treated cells.

30 ted oocytes resume meiosis, re-establish DNA replication competence in meiosis I shortly after germin

31 ingly, the Delta p48 mutant viruses retained replication competence in the apparent absence of p48 fo

32 dapted, variant coxsackievirus A21 exhibited replication competence in the lungs of hICAM-1 transgeni

33 omplete p9 protein were required to maintain replication competence in transfected equine cells; prov

34 dromedary MERS-CoV strains had similar viral replication competence in Vero-E6 cells and respiratory

35 strate that despite no overt loss of overall replication competence in vivo, this mutation results in

36 Xenopus, the only component missing for DNA replication competence is CDC6, which is synthesized fro

37 Selection for replication competence makes it possible to amplify and

38 Neither recovery of replication competence nor reversal of RPA effects occur

39 The similarity of virus tropism and replication competence of human and dromedary MERS-CoV f

40 ing and demonstrate that Cdt1 influences the replication competence of loaded Mcm2-7 helicases.

41 The observed replication competence of SHIV(CHN19) requires the full

42 the wild-type WN 3'SL markedly enhanced the replication competence of WN virus in mosquito cells but

43 (4) Replication competence: Polymerase chain reaction (PCR)

44 Despite this loss of replication competence, purified NS5B-C316A protein was

45 HCECs from the peripheral area retain higher replication competence, regardless of donor age.

46 Acquisition of DNA replication competence requires protein synthesis, but t

47 er component required for acquisition of DNA replication competence that is absent in mouse oocytes.

48 teraction is sufficient to confer autonomous replication competence to AAV in 293 cells.

49 ify sequences that could confer cell culture replication competence to replicons derived from chimpan

50 Replication competence was determined using coculture, w

51 in-treated cells, indicated that reduced DNA replication competence was due to the presence of a tran

52 Replication competence was maintained following either a

53 ave more complex mechanisms to establish DNA replication competence when compared to their Xenopus co

54 These mutations substantially enhanced replication competence when introduced into HRV-14 RNAs