ライフサイエンスコーパス: replication factor C

1 yeast CHL12 and has similarity to mammalian replication factor C.

2 teracts with multiple subunits of Drosophila replication factor C.

3 al DNA template was dependent on PCNA and on replication factor C.

4 nt on proliferating cell nuclear antigen and replication factor C.

5 provides a binding site for the clamp-loader Replication Factor C.

6 ncy in stimulation of the ATPase activity of replication factor C.

7 lity of PCNA to be loaded onto primed DNA by replication factor C.

8 egions of homology with the five subunits of Replication factor C.

9 pha, proliferating cell nuclear antigen, and replication factor C activate MutLalpha endonuclease to

10 The identification of both replication factor C and DNA helicases as critical for s

11 h three- and four-subunit complexes required replication factor C and proliferating cell nuclear anti

12 dition of M. thermoautotrophicum homologs of replication factor C and proliferating cell nuclear anti

13 rms a replication complex in the presence of replication factor C and proliferating cell nuclear anti

14 PCNA, together with replication factor C and replication protein A, stimulat

15 n A, proliferating cell nuclear antigen, and replication factor C and was active in the SV40 DNA repl

16 quirements for DNA polymerase alpha-primase, replication factor C, and PCNA.

17 ntenance (MCM) 3' --> 5' DNA helicase, PolB, replication factor C, and proliferating cell nuclear ant

18 sence of proliferating cell nuclear antigen, replication factor C, and single-stranded binding protei

19 d circular DNA do in fact support MutSbeta-, replication factor C-, and PCNA-dependent activation of

20 Three distinct forms of replication factor C are known to play vital roles in ge

21 ly loaded around effector DNA by its loader, replication factor C, are ubiquitinated.

22 These functions include loading onto DNA by replication factor C, as well as Okazaki fragment synthe

23 athway, FEN1 was functional without PCNA and replication factor C but required the DNA synthesis, whi

24 PCNA is loaded onto DNA by replication factor C, but it has been unknown how PCNA i

25 structural gene for the large subunit of DNA replication factor C (cdc44/rfc1) causes striking increa

26 ith mutations affecting the large subunit of replication factor C (Cdc44p or Rfc1p) in Saccharomyces

27 repair protein (248kDa) and the five-subunit replication factor C clamp loader (250 kDa).

28 and essential DNA polymerase, and a modified Replication Factor C clamp--loader complex.

29 esis, and the localization and activation of replication factor C complex (RFC) subunits.

30 tion in the large subunit of the replicative replication factor C complex (rfc1-1) increased the expa

31 ase delta/proliferating cell nuclear antigen/replication factor C complex on telomeric templates that

32 FC3 encode three of the five subunits of the replication factor C complex, which is required to load

33 rotein family, which include subunits of the Replication factor C complex.

34 of proteins including components of the DNA replication factor C complex.

35 ohesion establishment factor, the Ctf18-RFC (replication factor C) complex.

36 rase epsilon, replication protein A, and two replication factor C complexes on chromatin.

37 action of FEN1 in the presence of PCNA and a replication factor C-containing fraction.

38 log 6, Exonuclease 1, replication protein A, replication factor C-Delta1N, proliferating cell nuclear

39 liferating cell nuclear antigen clamp loader replication factor C, DNA polymerase delta, and DNA liga

40 re assembled around DNA by the clamp loader, replication factor C, efficiently.

41 ng cell nuclear antigen and the clamp loader replication factor C facilitated DNA synthesis with Dpo3

42 ticipation that the discovery of this unique replication factor C homolog will lead to critical insig

43 Human replication factor C (hRFC) is a five-subunit protein co

44 Human replication factor C (hRFC) is a multi-subunit protein c

45 a its non-conserved C-terminal domain (CTD); replication factor C interaction results in approximatel

46 Replication factor C is required to load proliferating c

47 Eukaryotic replication factor C is the heteropentameric complex tha

48 conformations matching the helical pitch of Replication Factor C, it is not biased toward a right-ha

49 Here we show that the Elg1 replication factor C-like complex (Elg1-RLC) functions i

50 factor is loaded onto DNA by the Rad24-RFC (replication factor C-like complex with Rad24) clamp load

51 es now present data strongly implicating the replication factor C-like complex, Elg1/ATAD5-RLC, in th

52 Then replication factor C loads a proliferating cell nuclear

53 the nascent strand from polymerase alpha to replication factor C, one possibility is that this step

54 tant showed a defect in the interaction with replication factor C or in loading by this complex.

55 ix purified human proteins: AP endonuclease, replication factor C, PCNA, flap endonuclease 1 (FEN1),

56 S. pombe Uve1p, Rad2p, DNA polymerase delta, replication factor C, proliferating cell nuclear antigen

57 system comprised of MutS alpha, MutL alpha, replication factor C, proliferating cell nuclear antigen

58 th the 9-1-1 heterotrimer reminiscent of the replication factor C/proliferating cell nuclear antigen

59 subunits of the origin recognition complex, replication factor C proteins, MCM DNA-licensing factors

60 ating cell nuclear antigen (PCNA) loading by replication factor C, providing a potential mechanism fo

61 The human DNA damage sensors, Rad17-replication factor C (Rad17-RFC) and the Rad9-Rad1-Hus1

62 ation factors, and the clamp loader complex (replication factor C) remained tethered to chromatin.

63 Replication factor C (RF-C) and proliferating cell nucle

64 The five subunit replication factor C (RF-C) complex plays a critical rol

65 Replication factor C (RF-C) complex plays an important r

66 Replication factor C (RF-C) is a five subunit DNA polyme

67 Yeast replication factor C (RF-C) is a heteropentamer encoded

68 Eukaryotic replication factor C (RF-C) is a heteropentameric comple

69 Replication factor C (RF-C), a complex of five subunits,

70 Replication factor C (RF-C), a complex of five subunits,

71 ating cell nuclear antigen (PCNA) loading by replication factor C (RFC) acts as the initial sensor of

72 oliferating cell nuclear antigen (PCNA), and replication factor C (RFC) and a reconstituted Mlh1-Pms1

73 , proliferating cell nuclear antigen (PCNA), replication factor C (RFC) and DNA polymerase delta.

74 plication clamp PCNA is loaded around DNA by replication factor C (RFC) and functions in DNA replicat

75 Replication factor C (RFC) and proliferating cell nuclea

76 Fractions that contained replication factor C (RFC) and proliferating cell nuclea

77 en (PCNA), and show that PCNA, together with replication factor C (RFC) and replication protein A (RP

78 Replication factor C (RFC) and the proliferating cell nu

79 Replication factor C (RFC) catalyzes assembly of circula

80 The eukaryotic equivalents are the replication factor C (RFC) clamp loader and the prolifer

81 The eukaryotic replication factor C (RFC) clamp loader is an AAA+ spira

82 We find that the replication factor C (RFC) clamp loader specifically inh

83 , and D subunits of Saccharomyces cerevisiae replication factor C (RFC) clamp loader, respectively, a

84 PCNA sliding clamps are loaded onto DNA by a replication factor C (RFC) clamp loader.

85 ell nuclear antigen (PCNA) sliding clamp and replication factor C (RFC) clamp-loading complex, using

86 ELG1 protein, which comprises an alternative replication factor C (RFC) complex and plays an importan

87 The multi-subunit replication factor C (RFC) complex loads circular prolif

88 visiae, this process involves an alternative replication factor C (RFC) complex that contains the fou

89 s, sliding clamps are loaded onto DNA by the replication factor C (RFC) complex, which consists of fi

90 igated the communication between subunits in replication factor C (RFC) from Archaeoglobus fulgidus.

91 e Methanosarcina acetivorans clamp loader or replication factor C (RFC) homolog.

92 s that are loaded onto DNA by clamp loaders [replication factor C (RFC) in eukaryotes].

93 Replication factor C (RFC) is a five-subunit complex tha

94 Replication factor C (RFC) is a five-subunit protein com

95 Replication Factor C (RFC) is a five-subunit protein com

96 Replication factor C (RFC) is a heteropentameric AAA+ pr

97 ing cell nuclear antigen loading onto DNA by replication factor C (RFC) is a key step in eukaryotic D

98 Replication factor C (RFC) is an AAA+ heteropentamer tha

99 netic experiments reveal that ATP binding to replication factor C (RFC) is sufficient for loading the

100 Rad17 homologs have extensive homology with replication factor C (RFC) subunits (p36, p37, p38, p40,

101 tin by a complex of Rad17 and the four small replication factor C (RFC) subunits (Rad17-RFC) in respo

102 Pase, is the bacterial homolog of eukaryotic replication factor C (RFC) that loads the sliding clamp

103 24 interacts with the four small subunits of replication factor C (RFC) to form the RFC-Rad24 complex

104 ometry to contain Rfc2 and Rfc3, subunits of replication factor C (RFC), a five subunit protein that

105 In addition, DNA replication factor C (RFC), a protein complex that facil

106 and DNA binding by Saccharomyces cerevisiae replication factor C (RFC), and present the first kineti

107 tein A (RFA), the 3' primer binding complex, replication factor C (RFC), and proliferating cell nucle

108 l nuclear antigen (PCNA) and show that PCNA, replication factor C (RFC), and replication protein A (R

109 y the Saccharomyces cerevisiae clamp loader, replication factor C (RFC), and the DNA damage checkpoin

110 The clamp loader, replication factor C (RFC), can reverse this mark by unl

111 When loaded onto primed DNA templates by replication factor C (RFC), PCNA acts to tether the poly

112 tionation of these crude extracts identified replication factor C (RFC), proliferating cell nuclear a

113 several DNA replication proteins, including replication factor C (RFC), proliferating cell nuclear a

114 on, hLigI interacts with and is inhibited by replication factor C (RFC), the clamp loader complex tha

115 is study, we describe an association between replication factor C (RFC), the clamp loader, and DNA li

116 l nuclear antigen, a DNA sliding clamp, and, replication factor C (RFC), the clamp loader.

117 dogenous and transfected Brd4 interacts with replication factor C (RFC), the conserved five-subunit c

118 utation in RFC4, encoding a small subunit of replication factor C (RFC), was found to display allele-

119 Unlike replication factor C (RFC), which uses the 3' primer/tem

120 A function, we have designed a new assay for replication factor C (RFC)-catalyzed loading of PCNA ont

121 proliferating cell nuclear antigen (PCNA) in replication factor C (RFC)-catalyzed loading of the clam

122 e-molecule analysis, we demonstrate that the replication factor C (RFC)-CTF18 clamp loader (RFC(CTF18

123 hat Ctf18, Ctf8, and Dcc1, the subunits of a Replication Factor C (RFC)-like complex, are essential f

124 with proliferating cell nuclear antigen and replication factor C (RFC).

125 nctions by a clamp loader molecular machine, replication factor C (RFC).

126 tf18, a homologue of the p140 subunit of the replication factor C (RFC).

127 interact with their associated clamp loader, replication factor C (RFC).

128 r antigen (PCNA), and hRad17 has homology to replication factor C (RFC).

129 DNA requires the activity of a clamp-loader [replication factor C (RFC)] complex and the energy deriv

130 a nucleotide-bound eukaryotic clamp loader [replication factor C (RFC)] revealed a different and mor

131 Human replication factor C (RFC, also called activator 1) is a

132 Replication factor C (RFC, also called activator 1), in

133 Replication factor C (RFC, also called Activator I) is p

134 ating cell nuclear antigen (PCNA, clamp) and replication factor C (RFC, clamp loader), we have examin

135 The DNA damage clamp loader replication factor C (RFC-Rad24) consists of the Rad24 p

136 CTF7/ECO1, POL30 (PCNA), and CHL12/CTF18 (a replication factor C [RFC] homolog) genetically interact

137 loader gamma complex (homolog of eukaryotic Replication Factor C, RFC).

138 re of the five-protein clamp loader complex (replication factor-C, RFC) of the yeast Saccharomyces ce

139 the structural gene for the large subunit of replication factor C (rfc1), which loads PCNA onto DNA,

140 s two similar small subunits (M. acetivorans replication factor C small subunit (MacRFCS)) and one la

141 ucturally homologous proteins, including the replication factor-C small subunit (RFCS).

142 ding proteins have been reported previously: replication factor C (the PCNA clamp loader), family B D

143 loaded onto the template-primer junction by replication factor C, the C-terminal domain of PCNA medi

144 this process through a pathway that includes replication factor C, the chromatin assembly factor Asf1

145 The ATPase activity of replication factor C was characterized and found to be s

146 a circular substrate without the addition of replication factor C, which is the protein responsible f

147 nterfaces by the ATP-dependent clamp loader, Replication Factor C, whose clamp-interacting sites form

148 loaded onto DNA by a dedicated complex, the replication factor C, whose mechanism has been studied i

149 Complexes of replication factor C with a N-terminal truncation (Delta

150 gammaS), a nonhydrolyzable analog of ATP, to replication factor C with a N-terminal truncation (Delta

151 Our results demonstrate that S. cerevisiae Replication Factor C (yRFC) can load yPCNA onto 5'-ssDNA