ライフサイエンスコーパス: replication machinery

1 active process, not a titration of maternal replication machinery.

2 essential role at the core of the minicircle replication machinery.

3 emphasizing their functional role in T4 DNA replication machinery.

4 ynthesis of the C strand by the conventional replication machinery.

5 nable to productively interact with the Con1 replication machinery.

6 ex) helicase and triggers disassembly of the replication machinery.

7 ntigen (PCNA), an essential component of the replication machinery.

8 t and interacts with components of the viral replication machinery.

9 with components of the viral translation and replication machinery.

10 and polymerase that is seen in the bacterial replication machinery.

11 iting primase, an essential component of the replication machinery.

12 te interactions with other components of the replication machinery.

13 nism that is coupled to the conventional DNA replication machinery.

14 at each is a critical component of the viral replication machinery.

15 SF1 is important for the processivity of the replication machinery.

16 e DNA loaded gp45 coupled late transcription-replication machinery.

17 of the genome as accessory helicases to the replication machinery.

18 at functions in organizing the mutagenic DNA replication machinery.

19 cation forks and directly interacts with the replication machinery.

20 ns as a stimulatory regulator of NS5B in HCV replication machinery.

21 rus DNA can be replicated solely by the host replication machinery.

22 opoisomerases may also function ahead of the replication machinery.

23 ecruitment to DNA lesions encountered by the replication machinery.

24 lycosides with stem-loop I (SLI) of the IncB replication machinery.

25 NA lesions that block the progression of the replication machinery.

26 e question of how they are recognized by the replication machinery.

27 ly associates with any components of the DNA replication machinery.

28 the replication fork are key elements of the replication machinery.

29 binding protein (OBP) that recruits the core replication machinery.

30 amage and secondary structures can stall the replication machinery.

31 lesions in the template strand block the DNA replication machinery.

32 that MUM2 influences the function of the DNA replication machinery.

33 ng of PCNA, a requisite component of the DNA replication machinery.

34 en clamp loader/sliding clamp complex of the replication machinery.

35 could play a role in lesion bypass by the T4 replication machinery.

36 nclear if they interact differently with the replication machinery.

37 usly unrecognized function of the eukaryotic replication machinery.

38 been replicated in their entirety by the T4 replication machinery.

39 V light-induced DNA lesions block the normal replication machinery.

40 the expression of specific components of the replication machinery.

41 mma B, a core component of the mitochondrial replication machinery.

42 ia might also be recognized by borrelial DNA replication machinery.

43 ic chromatin structure, and the conventional replication machinery.

44 after inducing the accumulation of host DNA replication machinery.

45 rentiation program and inducing the host DNA replication machinery.

46 ure that aids DNA to segregate away from the replication machinery.

47 prevent deleterious effects on the cellular replication machinery.

48 olve interference with this component of the replication machinery.

49 e they colocalize with components of the DNA replication machinery.

50 nisms for taking control of the cellular DNA replication machinery.

51 possible association between Topo IV and the replication machinery.

52 ein A is an important constituent of the DNA replication machinery.

53 which in turn act as mobile tethers for the replication machinery.

54 s in the template strand pose a block to the replication machinery.

55 tively regulating positive modulators of the replication machinery.

56 nteracting with proteins within the cellular replication machinery.

57 implications for the RNA processing and DNA replication machinery.

58 (DHFR), as well as the components of the DNA replication machinery.

59 ng interactions with other components of the replication machinery.

60 use them for the construction of functional replication machinery.

61 spatially distinct from that occupied by the replication machinery.

62 lesions and their recognition by the E. coli replication machinery.

63 inds the DNA double helix ahead of the other replication machinery.

64 constitutes an inevitable challenge for the replication machinery.

65 elps solve a wide range of challenges to the replication machinery.

66 on viral factors E1 and E2 and the cellular replication machinery.

67 y and functioning of the viral transcription/replication machinery.

68 lear antigen and other components of the DNA replication machinery.

69 tes and interacts with the components of the replication machinery.

70 matin pose significant challenges to the DNA replication machinery.

71 s of infected cells to set up the functional replication machinery.

72 ichromosomes that are replicated by the host replication machinery.

73 s stimulated by interaction of Eco1 with the replication machinery.

74 rus encodes most, if not all, of its own DNA replication machinery.

75 ing the virus to gain access to the cellular replication machinery.

76 merase holoenzyme is a unique feature of the replication machinery.

77 arities between the bacterial and eukaryotic replication machineries.

78 y block the progression of transcription and replication machineries.

79 quires the separate trafficking of the viral replication machinery, a matrix protein (M) and a glycop

80 y creates a requirement for reloading of the replication machinery, a potentially mutagenic process.

81 anifested in coordinated mobilization of the replication machinery, a process that we hypothesize may

82 the replication compartment allow the virus replication machinery an access to plentiful ATP, facili

83 (poliota), like poleta, associates with the replication machinery and accumulates at stalled replica

84 (poliota), like poleta, associates with the replication machinery and accumulates at stalled replica

85 alpha as an essential component of the mtDNA replication machinery and as the first component of the

86 protein NSP2 is a component of the rotavirus replication machinery and binds single-stranded RNA coop

87 ell division will occur and which places the replication machinery and chromosomal loci at defined lo

88 t replication forks to avoid stalling of the replication machinery and consequent genomic instability

89 hese genomes are fully dependent on the host replication machinery and contribute few, if any, replic

90 in interphase nuclei to both engage the host replication machinery and enable the plasmids to adhere

91 l conservation of some components of the DNA replication machinery and enzymes for DNA precursor bios

92 o0A are genes encoding components of the DNA replication machinery and genes that govern flagellum bi

93 es is significant, since dissociation of the replication machinery and inability to efficiently recov

94 sequence of T. litoralis with a focus on the replication machinery and inteins.

95 proteins are critical components of the DNA replication machinery and mark the site of initiation.

96 progression, and Claspin interacts with the replication machinery and might therefore monitor normal

97 a large dsDNA virus that encodes its own DNA replication machinery and other enzymes involved in DNA

98 entire process of TLS in vitro using E. coli replication machinery and Pol IV, we observed that a rep

99 Comparing the DNA replication machinery and processes of parasites and the

100 ion through distinct pathways to inhibit the replication machinery and provide evidence that stepwise

101 must also be copied by the conventional DNA replication machinery and replenished by telomerase, sug

102 s of chromosomal replication can disrupt the replication machinery and result in mutagenesis or letha

103 udes cellular repair pathways can arrest the replication machinery and stall the cell cycle.

104 ment of sister chromatid cohesion to the DNA replication machinery and suggest that the assembly of c

105 replication origins) modulate the ubiquitous replication machinery and supports an emerging model tha

106 lts from direct interactions between the RNA replication machinery and the capsid proteins.

107 nce of DNA "ends" poses problems for the DNA replication machinery and the cell's damage response sys

108 e mutagenic, their interference with the DNA replication machinery and the elicited DNA damage respon

109 the combined action of the conventional DNA replication machinery and the reverse transcriptase, tel

110 action of telomerase, the semi-conservative replication machinery and the stabilization of the repli

111 an essential and conserved component of the replication machinery, and a DNA structure reveals a mec

112 dence that the YSS is essential to the viral replication machinery, and contributes to replication en

113 een histone methylation and the metazoan DNA replication machinery, and defining a pivotal aetiologic

114 eracts with PCNA, a central component of the replication machinery, and is recruited to sites of DNA

115 dc45, MCM2-7 and PCNA, components of the DNA replication machinery, and is required for normal replic

116 known E. coli DNA polymerases, parts of the replication machinery, and RecA recombinase.

117 r DNA amplification, emulating the bacterial replication machinery, and resembling PCR but under isot

118 , is co-expressed with components of the DNA replication machinery, and that Donson is essential for

119 (PCNA), the platform for assembly of the DNA replication machinery, and that unloading of Rad51 by Sr

120 ted cells by parasitism of the intact virus' replication machinery, and through replication with the

121 , archaea have only a subset of the eukaryal replication machinery, apparently needing fewer polypept

122 nded DNA-binding proteins (SSBs) and the DNA replication machinery are found in all organisms, but th

123 er, several core components of the bacterial replication machinery are unrelated or only distantly re

124 hich the high-fidelity DNA polymerase in the replication machinery arrested at the primer terminus is

125 nition complex 2 (Orc2), a member of the DNA replication machinery, as a Plk1 substrate and have show

126 re we review how cohesin is regulated by the replication machinery, as well as recent evidence that c

127 -stranded DNA resulting from stalling of the replication machinery at DNA damage sites and to recogni

128 synthate produced by plants, and viruses use replication machinery at the host's expense.

129 gulation of CDK activity interfaces with the replication machinery at two discrete execution points.

130 ssion of the nascent DNA or migration of the replication machinery away from the blocking lesion to a

131 estigated whether they induce pausing of the replication machinery before serving as the template bas

132 e data indicate that the activity of the DNA replication machinery, beyond TP53 mutation status, dete

133 e ORF3 sequence, were tolerated by the viral replication machinery, but infectious virus could not be

134 Although known components of the replication machinery can influence telomere length equi

135 ovel insight into the mechanism by which the replication machinery can switch between replication, pr

136 argest RNA viruses, and their genomes encode replication machinery capable of efficient replication o

137 DNA damage and perturbation of replication machinery causes replication stress, charact

138 propose that MutS directly contacts the DNA replication machinery, causing a dynamic change in the o

139 genome increases the error frequency of the replication machinery, causing mutations that contribute

140 ir of the damage but also changes in the DNA replication machinery, chromatin, and transcription that

141 to the inherent limitations of the canonical replication machinery, chromosomes gradually lose termin

142 syltransferase PARP14 interacts with the DNA replication machinery component PCNA and promotes replic

143 The viral replication machinery consists of four nonstructural pro

144 These findings suggest the presence of replication machinery-coupled and -independent pathways

145 tylation occurs only in association with the replication machinery: disruption of the interaction bet

146 quently, prophage DNA is spooled through the replication machinery, drawing the prophage ends togethe

147 s thought that stalling of the mitochondrial replication machinery during DNA synthesis is a prominen

148 predicted to come into contact with the DNA replication machinery during fork arrest.

149 ransits from being dependent on the cellular replication machinery during latency to commandeering bo

150 sable phage Mu and the host Escherichia coli replication machinery during repair of Mu insertions, wh

151 nthesized histones and components of the DNA replication machinery during the S phase of the cell div

152 The E. coli replication machinery employs a beta clamp that tethers

153 after initiation, or (iii) stalled when the replication machinery encountered an intramolecular dupl

154 ssociation between PI4KIIIbeta and the viral replication machinery exists and, if it does, whether as

155 ssion of the six components of the EBV lytic replication machinery failed to rescue replication by Z(

156 confront cellular repair, transcription, and replication machinery following exposure to TPZ and offe

157 DNAzyme sequences are implemented as nicking/replication machineries for the amplified, multiplexed a

158 ments for excision and the plasmid R6K-based replication machinery for DNA amplification, permits one

159 ly in order to concentrate and arrange viral replication machinery for efficient viral RNA synthesis.

160 avirus type 1 (BPV1) depends heavily on host replication machinery for genome duplication.

161 tivating and highjacking the host cell's DNA replication machinery for its own reproduction purposes

162 E2, papillomaviruses depend heavily on host replication machinery for replication of their viral gen

163 a as nuclear plasmids and rely upon the host replication machinery for replication.

164 ncer elements work together with the general replication machinery for site-specific origin utilizati

165 s and to recognize the components of the DNA replication machinery for ubiquitination by Rad6.

166 Our results indicate that the core DNA replication machinery from plants is more similar to ver

167 malian telomeres pose a challenge to the DNA replication machinery, giving rise to replication-depend

168 combinant DNA technology, the alphavirus RNA replication machinery has been engineered for high-level

169 The Escherichia coli DNA replication machinery has been used as a road map to unc

170 Presumably, either the plastid replication machinery has means of removing nucleoid pro

171 bble and promoting the assembly of the viral replication machinery; however, direct confirmation of t

172 on the synthesis of components of the 29 DNA replication machinery (i.e., terminal protein and DNA po

173 i/regions pose greater challenges to the DNA replication machinery (i.e., the replisome) than others.

174 RTP, and suggest that RTP interacts with the replication machinery in a manner that directly contribu

175 The simplified replication machinery in archaea may provide a simplifie

176 icative polymerases, suggesting that the DNA replication machinery in bacteria arose independently.

177 y to encode additional components of the DNA replication machinery in C. elegans.

178 receptor tyrosine kinase to the nuclear DNA replication machinery in cancer cells.

179 , (R)-sBu and (S)-sBu, are recognized by DNA replication machinery in HEK293T human embryonic kidney

180 provide a comprehensive view of the core DNA replication machinery in plants.

181 deletion mutant parasitism of the wild-type replication machinery in superinfected cells.

182 e progression and activate the host cell DNA replication machinery in these cells, changes essential

183 hysically associated with the lagging-strand replication machinery in these complexes.

184 ing the differences and peculiarities of the replication machinery in trypanosomatids, including how

185 acts with the processivity factor of the DNA replication machinery in vivo and in vitro.

186 are made accessible to the transcription and replication machinery in vivo.

187 HSV-1's replication machinery includes a trimeric helicase-prima

188 en the bacterial and the archaeal/eukaryotic replication machineries, including but not limited to de

189 the normal progression of the mitochondrial replication machinery, including DNA unwinding by Twinkl

190 a large dsDNA virus that encodes its own DNA replication machinery, including enzymes involved in nuc

191 ism by which essential components of the DNA replication machinery interact with the replication chec

192 with the cell membrane to release the viral replication machinery into the host cell's cytoplasm.

193 The DNA replication machinery invariably encounters obstacles th

194 The DNA replication machinery is an important target for antibio

195 This analysis establishes that the core DNA replication machinery is highly conserved across plant s

196 Assembly of the replication machinery is highly conserved and tightly re

197 The replication machinery is highly regulated by replication

198 icance of the components of the rabies virus replication machinery is incomplete.

199 How the replication machinery is loaded at origins of DNA replic

200 lymerases (pol) iota and Rev1 at the stalled replication machinery is mediated by the ubiquitin-bindi

201 tion between DnaA bound at each site and the replication machinery is not required for regulation of

202 A unique topological challenge to the replication machinery is posed by RNA-DNA hybrids, commo

203 mediate negative strands by the picornavirus replication machinery is presumably mediated by cis-acti

204 plication of the latent genome, the cellular replication machinery is recruited.

205 strongly supports a hypothesis that the DNA replication machinery is required for proper sister chro

206 ocess requires de novo assembly of the viral replication machinery, large ribonucleoprotein complexes

207 DNA damage can stall the DNA replication machinery, leading to genomic instability.

208 Components of the DNA replication machinery localize into discrete subnuclear

209 en either the template DNA is damaged or the replication machinery malfunctions.

210 Thus, the DNA replication machinery may confer different developmental

211 y provides the first suggestion that the DNA replication machinery may have redox-sensitive activitie

212 n the opposite direction, at which stage the replication machinery may simply dissociate before the n

213 s for the virus, provided by the host cell's replication machinery, may be mediated by further intera

214 t, it has been proposed that the herpesvirus replication machinery might replicate AAV DNA.

215 ich during re-synthesis of resected DNA, the replication machinery must catch up with the preceding p

216 The Escherichia coli DNA replication machinery must frequently overcome template

217 ed during early eukaryote evolution from the replication machinery of a retrotransposable element.

218 ential to invert is probably inherent in the replication machinery of all herpesviruses, irrespective

219 Molecular parasites that utilize the replication machinery of cells or of in vitro amplificat

220 AR co-sedimented with components of the DNA replication machinery of cells that entered S phase.

221 Virophages are viruses that rely on the replication machinery of other viruses to reproduce with

222 In the case of adenovirus coinfection, the replication machinery of the host cell performs AAV DNA

223 Satellite RNAs usurp the replication machinery of their helper viruses, even thou

224 t Activation (INPACT) system is based on the replication machinery of tobacco yellow dwarf mastreviru

225 ackaging into BV virions may depend upon the replication machinery of wasps.

226 gin proximal genes, but interaction with the replication machinery or other features of DNA structure

227 The mechanism by which the eukaryotic DNA-replication machinery penetrates condensed chromatin str

228 The DNA replication machinery plays additional roles in S phase

229 prevents the collision of transcription and replication machineries, plays a key role in maintaining

230 ors of chromatin assembly/remodeling and DNA replication machineries (POLE3/CHRAC17 and POLE4), the s

231 The bacterial DNA replication machinery presents new targets for the devel

232 ence of DNA synthesis inhibitors, core viral replication machinery proteins accumulate in intranuclea

233 ve a simplified subset of the eukaryotic DNA replication machinery proteins and possess initiators th

234 y role in assembling and recruiting the core replication machinery proteins in the initial stages of

235 transient cotransfection, the six KSHV core replication machinery proteins successfully replicated a

236 plex virus replication genes and encode core replication machinery proteins that are typically essent

237 xtures of the purified T4 late transcription-replication machinery proteins: gp45 (sliding clamp), gp

238 vitro reconstitution of the bacteriophage T4 replication machinery provides a novel system for fast a

239 hromatin, the physiological substrate of DNA replication machinery, regulates DNA replication remains

240 ic double-strand break demonstrated that the replication machinery (replisome) and DNA synthesis are

241 through origin-independent reloading of the replication machinery (replisome) to ensure complete dup

242 foci in positions similar to that of the DNA replication machinery (replisome).

243 Collisions between cellular DNA replication machinery (replisomes) and damaged DNA or im

244 ously visualized replication origins and the replication machinery (replisomes) inside live cells.

245 tions that mimic those in cycling cells, the replication machinery showed substantial stalling at sit

246 To appropriate the cellular DNA replication machinery, simian virus 40 (SV40) large T an

247 lis utilizes a DNA polymerase III holoenzyme replication machinery similar to that of E. coli.

248 titration of a maternal component of the DNA-replication machinery slows DNA synthesis and induces a

249 ould alter a key functional component of the replication machinery, specifically DnaG primase.

250 ch these DNA polymerases are targeted to the replication machinery stalled at a lesion site has remai

251 that the targeting of this polymerase to the replication machinery stalled at a lesion site is achiev

252 e manner by which hPoleta is targeted to the replication machinery stalled at a lesion site remains u

253 votal role in the targeting of Poleta to the replication machinery stalled at DNA lesions, interactio

254 a repair enzyme as a component of the viral replication machinery suggests that, for poxviruses, DNA

255 components of the kinetoplastid nuclear DNA replication machinery - the factors that demarcate sites

256 nt proteins to M and to a constituent of the replication machinery, the phosphoprotein (P).

257 ombe exploits the intrinsic asymmetry of DNA replication machinery--the difference between the replic

258 Movement of the DNA replication machinery through the double helix induces a

259 Depriving viruses of crucial replication machinery, TIPs would reduce viral loads.

260 viruses are small DNA viruses that use plant replication machinery to amplify their genomes.

261 The ability of the bacterial replication machinery to bypass the lesions does not cor

262 sating for the inability of conventional DNA replication machinery to completely duplicate the ends o

263 nding, where the virus utilizes the host DNA replication machinery to establish itself as a low-copy-

264 on-like [KIL-d] element reprograms the viral replication machinery to induce mutagenesis and genomic

265 However, how FANCM interacts with the replication machinery to promote traverse remains unclea

266 damage tolerance process that allows the DNA replication machinery to replicate past nucleotide lesio

267 ction(s) can be compensated by the bacterial replication machinery to support the PCV DNA replication

268 e case), strongly indicating attempts by the replication machinery to surpass the stalled replication

269 ind boxes I and II, permitting access of the replication machinery to the Ori(s) sequences.

270 nstead, KSHV LANA recruits the host cell DNA replication machinery to the replication origin.

271 CMG helicase powers ahead of the eukaryotic replication machinery to unwind DNA, in a process that r

272 e results indicate the ability of alphavirus replication machinery to use a multitude of AU-rich RNA

273 der to propagate, AAV relies on the cellular replication machinery together with functions supplied b

274 -stranded DNA genome that relies on cellular replication machinery together with functions supplied b

275 est a spatial reorganization of the host DNA replication machinery upon HPV DNA replication or E1 and

276 to Escherichia coli, and that the endogenous replication machinery uses them to accurately replicate

277 The DNA replication machinery, various regions of the chromosome

278 nce for a direct recruitment of UHRF1 by the replication machinery via DNA ligase 1 (LIG1).

279 lt, whereby proteins can be recruited to the replication machinery via the back of PCNA and be held i

280 o direct interaction of IFI35 with the viral replication machinery was observed, we found that IFI35

281 and downstream components of the processive replication machinery was specifically disrupted.

282 enous templates was dependent upon the viral replication machinery, was temporally coincident with vi

283 ial physical interaction of ATM with the DNA replication machinery, we found that ATM co-precipitates

284 iated proteins that are not part of the core replication machinery were shown to affect the timing of

285 the interplay between the recombination and replication machinery when recombination intermediates a

286 evidence that poleta targets poliota to the replication machinery, where it may play a general role

287 evidence that poleta targets poliota to the replication machinery, where it may play a general role

288 DNA replication depends on host cellular DNA replication machinery, whereas lytic cycle DNA replicati

289 plification (cHDA) system is based on the T7 replication machinery, which includes the processive T7

290 d stably maintaining the architecture of the replication machinery while keeping the fork moving.

291 -chromatin contacts allow passage of the DNA replication machinery while PSC-PSC interactions prevent

292 jor damage-sensing mechanisms connecting the replication machinery with DNA repair pathways.

293 igin of replication to provide access to the replication machinery with the consequent initiation of

294 n and to study the interactions of the viral replication machinery with the host cell innate immune s

295 molecules to measure the activity of the DNA-replication machinery with the visualization of fluoresc

296 n of telomeres requires the conventional DNA replication machinery, yet little is known about how DNA