ライフサイエンスコーパス: replication study

1 all 12 SNPs were confirmed in an independent replication study.

2 consideration to whether it is a de novo or replication study.

3 risons between NC1 and the autism group as a replication study.

4 a meta-analysis with a published GWAS and a replication study.

5 spectively) but not to cephalosporins in the replication study.

6 ant predictor of the P-value in a subsequent replication study.

7 hese experiments will then be published in a Replication Study.

8 with the risk of clinical CAD in this large replication study.

9 y identified, and 5 SNPs were later found in replication studies.

10 Two additional cohorts were used for replication studies.

11 the initial GWAS were not associated in the replication studies.

12 tiology of NHL, and should be prioritized in replication studies.

13 that variant and facilitate the planning of replication studies.

14 esting additional variants is commonplace in replication studies.

15 novel risk loci that require confirmation by replication studies.

16 ary in the absence of converging evidence or replication studies.

17 DCYAP1R1 were genotyped in our study and six replication studies.

18 diseases, often with inconsistent results in replication studies.

19 mbined meta-analysis of all 22 discovery and replication studies.

20 associated overall and in 3 of 5 individual replication studies.

21 identify SNPs that can be pursued in future replication studies.

22 (cases) and 3,182 controls), an independent replication study (1,440 cases and 1,316 controls) and a

23 N22 (discovery-study allelic P=6.6 x 10(-4); replication-study allelic P=5.6 x 10(-8)), which encodes

24 Additional virus replication studies also revealed that the Vif protein o

25 type 1a replicons should be useful for basic replication studies and for antiviral development.

26 sis for the design and interpretation of GWA replication studies and point to the importance of a cle

27 egrative summary, we review various types of replication studies and then discuss the most commonly v

28 Replication studies and understanding the roles of these

29 such two-stage data is to view stage 2 as a replication study and focus on findings that reach stati

30 rried out a genome-wide association scan and replication study and found an association between SLE a

31 rried out a genome-wide association scan and replication study and found an association between SLE a

32 ociated with ovarian cancer risk both in the replication study and in combined analyses.

33 This finding was confirmed in each replication study and overall meta-analysis (OR=1.24, 95

34 t GTF2I by heterogeneity mapping followed by replication studies, and pinpointed a possible causal va

35 he presence of real effects in a low-powered replication study, and instances of such association inc

36 al white populations were used for follow-up replication studies: another independent cohort of CAD-

37 Replication studies are clearly warranted, as such child

38 Replication studies are critical to investigation of com

39 Replication studies are needed to confirm our findings.

40 Future replication studies are needed to confirm these associat

41 Replication studies are needed to validate these results

42 Replication studies are required to confirm or refute th

43 Future independent replication studies are required to confirm these findin

44 only tentative evidence of association, and replication studies are required to establish their vali

45 s drug markers may not be inconsequential in replication studies, as is generally assumed.

46 In vitro CIRV replication studies based on isolated mitochondrial prep

47 In vitro CIRV replication studies based on isolated mitochondrial prep

48 atio of sample sizes between the initial and replication studies, but not on the underlying effect si

49 Replication studied by single DNA molecule analyses and

50 A combined analysis of the initial and replication studies by logistic regression showed CFLD t

51 In the replication study, CFLD was associated with the SERPINA1

52 s) and followed up three lead signals in six replication studies (combined N = 19,089).

53 Replication studies confirmed IL23R associations in inde

54 The replication study confirmed the association of the TGFbe

55 This is the first replication study confirming the effectiveness of a heal

56 case-control data can improve the design of replication studies considerably.

57 alysis of primary results was performed with replication studies containing 12 174 heavy and 11 290 l

58 Because the FISH replication studies could not directly distinguish betwe

59 Specifically, all five "replication" studies define a positively associated hapl

60 , we report the results of a discovery and a replication study, each involving a double-blind, placeb

61 This replication study evaluates the relationship between sea

62 tients and 400 controls from the U.S. and in replication studies for 308 POAG patients and 178 contro

63 covalently bonded, and carried out in vitro replication studies for the lesion-bearing substrate wit

64 Replication studies from several populations showed conf

65 op prediction intervals for the P-value in a replication study given the P-value observed in an initi

66 In the CABS replication study, Gln27 homozygous participants similar

67 Association replication studies have a poor track record and, even w

68 e association studies (GWAS) and large-scale replication studies have identified common variants in 7

69 Recent genome scans and replication studies have identified replicated linkage b

70 Several replication studies have reported confirmation of an ass

71 This extended replication study identified 2 additional asthma risk lo

72 Meta-analysis of the discovery and replication studies improved the association signal (p =

73 In independent replication studies in 16,373 women, each major allele w

74 in the Pune Maternal Nutrition Study (PMNS), replication studies in 3418 individuals from other India

75 which was followed by in silico and de novo replication studies in 37,691 and 17,642 additional east

76 enetic ancestry and ethnicity, and performed replication studies in an additional 531 Latinos.

77 n mapping was followed up by association and replication studies in an independent sample.

78 a useful asset for synthetic biology and DNA-replication studies in particular.

79 -wide genotyping of the European cohorts and replication studies in the Japanese cohort identified co

80 thnically matched controls, and we performed replication studies in two independent European cohorts.

81 We did replication studies in two independent populations consi

82 An independent replication study in 16 novel subjects confirmed these n

83 We performed a replication study in 175 trios consisting of probands wi

84 subsequent transmission disequilibrium test replication study in an independent cohort confirmed the

85 We then conducted a replication study in an independent cohort of men from t

86 A replication study in an independent sample from the Fram

87 69 individuals to 293,723 individuals, and a replication study in an independent sample of 111,349 in

88 Here we report an NVC QTL replication study in an independent sample of 213 AGRE f

89 A replication study in an independent set of Mexican Ameri

90 A replication study in Chinese (3,043 cases and 5,074 cont

91 osis household contact study in France and a replication study in families from South Africa to confi

92 Replication study in GenNet confirmed the association of

93 Here we conducted a GWAS and a replication study in Koreans using a total of 1,085 DTC

94 Using a genome-wide association and replication study in up to 100,000 individuals, we ident

95 of lipid levels in 8344 subjects followed by replication studies including 14 739 additional individu

96 hypertension in 11 816 subjects followed by replication studies including 69 146 additional individu

97 e rankings were followed up in a three-stage replication study including 4,064 cases and 4,685 contro

98 l associations that can be pursued in future replication studies, including an intergenic SNP, rs4761

99 Transfection and replication studies indicated that c-Jun and c-Fos can s

100 I review numerous replication studies indicating that AMT data is reliable

101 The Replication Study involved 34 MDD subjects, and yielded

102 Replication studies involving additional persons with co

103 Replication studies involving larger population samples

104 s further delineated in: (1) a pooling-based replication study involving an additional 500 AN patient

105 orts (n = 13,813) followed by two additional replication studies (n = 2,267) including approximately

106 orts) and followed up two lead signals in 13 replication studies (n = 27,591).

107 verall meta-analysis combining discovery and replication studies (n = 51,258).

108 t a genome-wide association (n = 17,967) and replication study (n = 13,615) to identify genetic loci

109 Replication study observed significant association signa

110 from 11 studies and followed up 6 SNPs in 3 replication studies of 2,198 cases and 4,918 controls.

111 We also carried out in vitro replication studies of a substrate containing a site-spe

112 In vitro replication studies of Pol iota show that it replicates

113 ction: Genetics and Environment, followed by replication studies of prioritized single nucleotide pol

114 whose bypass adheres to the "A-rule." Recent replication studies of the oxidized abasic lesion, 2-deo

115 ce analysis of HLA-DRB3 exon 2 in a targeted replication study of 281 informative T1D family members

116 lipoprotein(a) level measurements, and in a replication study of 379 patients with echocardiography-

117 In a large case-control replication study of 438 patients with SLE and 219 contr

118 A candidate gene replication study of association between refraction and

119 a trans-ancestry genome-wide association and replication study of blood pressure phenotypes among up

120 Finally, our replication study of rs6435326, rs1053517 and rs1801318

121 x GeneChip Human 20k cSNP Kit, followed by a replication study of the more promising results.

122 asthma risk loci by performing an extensive replication study of the results from the EVE Consortium

123 We further carried out in vitro replication studies on a substrate containing a site-spe

124 enes on metabolic outcomes; however, further replication studies on large samples are needed to confi

125 further genotyped this SNP in two subsequent replication studies (one with 3,750 women and the other

126 n the initial study (P = 0.0052), and in the replication studies (P = 0.032).

127 rther using other statistical methods and in replication study populations.

128 e 56% and 45% for the initial and subsequent replication studies, respectively.

129 In vitro and in vivo replication studies revealed that FodU can be mutagenic.

130 Furthermore, an independent replication study sample of 837 cases and 968 controls f

131 Replication studies should integrate genomics and transc

132 Both replication studies showed an association of the rs66304

133 The replication study showed again that the autism group use

134 he three novel SNPs were followed-up in nine replication studies (Stage 2; N = 11 995), with rs905938

135 Data from this replication study suggest that Kraepelinian schizophreni

136 ss to raw data and protocols, the conduct of replication studies, systematic integration of evidence

137 Our replication study tested 34 SNPs in 4,496 independent ca

138 Third, we demonstrate by in vitro replication studies that several such hairpin i-motifs a

139 lly genotyped in an independent family-based replication study that, after quality control, consisted

140 In independent replication studies the 17q21 locus showed strong associ

141 In the replication study, the genetic variant rs10455872 also s

142 In the replication study, this single nucleotide polymorphism e

143 erestimation of the genetic effect may cause replication studies to fail because the necessary sample

144 Here we extended the in vitro replication studies to two replicative polymerases, exon

145 This replication study used a much larger patient cohort to e

146 In replication studies using similar methodology, many of t

147 rone activity measurements and in vivo HIV-1 replication studies using the same NC mutants.

148 wide association analysis and an independent replication study using a total of 1131 bladder cancer c

149 gammaRIIA and FcgammaRIIIA in a case-control replication study, using allele-specific polymerase chai

150 Replication studies verified the significant findings by

151 A replication study was conducted in an independent, co-lo

152 nvestigations, a genome-wide association and replication study was conducted in two smoker cohorts to

153 A replication study was conducted using the SAGE sample wi

154 A replication study was performed in 240 nuclear Malian fa

155 A replication study was performed using data from the Gene

156 In a replication study, we analyzed (11)C-Pittsburgh Compound

157 In this replication study, we examined the six top-most associat

158 In a replication study, we genotyped 10 single-nucleotide pol

159 In this replication study, we reassessed whether these genes are

160 For a replication study, we selected 10 SNPs in six chromosoma

161 The same DNAs that were used for replication studies were also assembled into duplex DNAs

162 Two replication studies were conducted to assess the associa

163 Replication studies were performed using 1541 subjects f

164 ntribute to the mutational outcome, in vitro replication studies were performed.

165 Replication studies were rare (n = 4), and only 16 studi

166 structural region are likely to affect viral replication, studies were performed to evaluate the effe

167 However, further replication studies will be required before any such ass

168 TES effect, we performed detailed retroviral replication studies with an NSI/R5 (B-92BR021) and SI/X4

169 evated risk of lung cancer from the combined replication studies with an OR of 1.15 (95% CI, 1.04-1.5

170 iral life cycle, we carried out a systematic replication study with entire genomes of human papilloma

171 xposure in conjunction with a-priori planned replication studies would reduce the number of false pos