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2 nonpolar (D76V and D76I) residues increased replicational accuracy, while substitutions with negativ
5 formation, and the various components of the replicational and transcriptional machinery may be inter
6 and delta, respectively, and show that post-replicational bypass of UV-damaged DNA is severely inhib
8 tions favour the view that the process is co-replicational: DNA replication forks are anchored at the
9 recombination and sex has been selection for replicational fidelity and viability; without the recomb
10 sitive determinants of both dNTP binding and replicational fidelity within the highly conserved motif
12 Our findings suggest the possibility of co-replicational or co-transcriptional folding of G-quadrup
13 nalogies between the genome organization and replicational requirements of plant closteroviruses and
17 ighlight the potential importance of chronic replicational stress in promoting cancer development.
18 the ATR/Chk1- and 53BP1-mediated signal from replicational stress is received, BLM functions in multi
20 own that exposure of cells to high levels of replicational stress leads to permanent proliferation ar
21 y of mutant p53 to prevent arrest induced by replicational stress per se is primarily dependent on pr
25 es to therapeutically relevant low levels of replicational stress that allow limited proliferation.
26 the ERCC1-XPF endonuclease, is important for replicational stress tolerance in both budding and fissi
28 ests that, in response to DNA damage and DNA replicational stress, Chk1 and Chk2 may phosphorylate Cd
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