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1 simple fluorescent imaging for each lineage reporter.
2 rial Lux system is used as a gene expression reporter.
3 sing a novel cell surface Gaussia luciferase reporter.
4 g of genomic loci together with a cell cycle reporter.
5 belled detection antibody as a non-enzymatic reporter.
6 G stop codon located in a beta-galactosidase reporter.
7 codon-optimality or 5'UTR of the luciferase reporter.
8 (Jc1G), which encodes a secreted luciferase reporter.
9 eening assays with luciferase or fluorescent reporters.
10 mited by photon emission from single optical reporters.
11 thout the limitations associated with enzyme reporters.
12 were also recognized by KIR2DL2 and KIR2DL3 reporters.
13 ing of the apoptotic cells using quantum dot reporters.
14 w viral-based platforms with 2 specific gene reporters.
16 de and cisplatin increased NFkappaB promoter reporter activity and etoposide induced nuclear transloc
20 RARE-EGFP reporter axolotls showed divergent reporter activity in limbs undergoing PD duplication ver
21 induction of GR target genes and GRE-driven reporter activity without disrupting dexamethasone-induc
22 , whereas overexpression increased PPARalpha reporter activity, suggesting ACOT1 regulates PPARalpha
28 ate this system's utility in transcriptional reporter analysis, site-of-action experiments and exogen
30 omic annotation data and performing promoter-reporter and chromatin conformational capture (3C) studi
32 The expression of a protected fluorescent reporter and flux of a high-value metabolite are signifi
36 ared with the (14)C-iodoantipyrine perfusion reporter, and the perfusion-modifying drugs nicotinamide
37 and transgenic mice expressing recombinases, reporters, and inducible transcriptional activators are
38 uction of KAR2, PDI1, and beta-galactosidase reporters, and survival of ER stress, but it had no effe
39 partner alters the efficiency with which the reporter approaches the electrode surface, thus causing
40 lycoFRET), where terbium-labeled fluorescent reporters are irreversibly attached to receptors by meta
43 g computational network analysis, an in vivo reporter assay and physiological validation experiments.
44 77; RNA immunoprecipitation and a luciferase reporter assay confirmed that ilp7 and ilp8 are direct t
46 BPAF, Coum, 1-BP) of 16 compounds tested by reporter assay had estrogenic activity through mERbeta2.
47 oyed a Piwi-interacting RNA (piRNA)-targeted reporter assay in Drosophila ovary somatic sheet (OSS) c
48 purification (TRAP) and in vitro luciferase reporter assay indicate that mir-92a suppresses expressi
53 Pase activity of DHX9, and a transcriptional reporter assay suggests Nup98 supports DHX9-stimulated t
55 ombining computational modeling and the BiLC reporter assay, we identified several novel small-molecu
56 sing cAMP measurements and a transcriptional reporter assay, we observed that several constrained ago
58 etry, bioinformatics analysis and luciferase reporter assay, we showed that miR-K6-5p directly target
59 ncreased mRNA stability, as predicted by the reporter assay, while also markedly decreasing transcrip
62 assay experiments such as massively parallel reporter assays (MPRAs) and similar methods remains chal
65 assessed using different T-cell factor (TCF) reporter assays as a readout for Wnt/beta-catenin-depend
70 pha-SYN expression; while exogenous promoter-reporter assays failed to reproduce the similar outcomes
73 Chromatin immunoprecipitation and luciferase reporter assays revealed a direct binding of NANOG to a
75 ciated loci, we performed massively parallel reporter assays to screen candidate functional variants
76 transcription and replication in luciferase reporter assays, a mutant that may act as a phosphomimet
77 tion with low micromolar IC50s in cell-based reporter assays, inhibit Gas6-inducible motility in Axl-
78 activity of 69 TE subfamilies by luciferase reporter assays, spanning all major TE classes, and show
82 Due to intrinsic limitations of heterologous reporter assays, we sought to develop a gene editing app
93 oluminescence resonance-energy-based Antares reporter called Antares2, which offers improved signal f
94 lar administration of lentiviral, luciferase reporter cassettes (biosensors); we present real-time an
98 ically assessed using genetically engineered reporter cell lines that produce a fluorescent signal as
102 ort hairpin RNA (shRNA) targeted against the reporter coding region, we have characterized the dynami
103 a promoter-specific, fluorescent translation reporter confirmed clusters are the functional unit of g
105 t a stable full-length enterovirus 71 (EV71) reporter construct was used to visualize real-time viral
109 ion in vitro by use of both the TCV gRNA and reporter constructs did not reveal any sequence-specific
110 induced from transgenic plants carrying GUS reporter constructs of these genes indicated that these
112 used BAC recombineering to first create GFP reporter constructs, which were analysed for enhancer ac
116 paB and STAT3 transcription factor activated reporters during the earliest stages of development in l
117 ple knock-in of epitope tags and fluorescent reporters (e.g. Sox2-V5 and Sox2-mCherry); and (4) engin
119 presence of an EDC leads to activation of a reporter enzyme, reported through a straightforward colo
120 t nature allows fusion with affinity tags or reporter enzymes as well as efficient maleimide chemistr
122 veals rapid pulsatile level changes in Gata2 reporter expression in cells undergoing endothelial-to-h
123 rence fluorescent protein is nested within a reporter fluorescent protein to control for such artifac
124 ns in and around this core cluster express a reporter for corticotrophin-releasing hormone (Bar(CRH)
125 using a reporter virus expressing a surface reporter for gentle and efficient purification with long
126 we developed a specific translocation-based reporter for monitoring Fus3 activity in individual live
127 n enzymatically generated at biosensors as a reporter for the presence of nonelectroactive target mol
129 proliferating human cells, using fluorescent reporters for AMPK activity, Akt activity, and cytosolic
133 ibited serum response factor (SRF)-dependent reporter gene (SRE-LUC) activity and mRNA expression of
135 e Gfi1(Cre) mice, both for gene deletion and reporter gene activation, these data are significant and
136 l MRTF/SRF inhibitor, markedly decreased SRF reporter gene activity and showed a greater inhibitory e
139 vity from the NtPDR1 promoter in situ with a reporter gene and found that, although NtPDR1 expression
143 d potent transcriptional activities in a VDR reporter gene assay, and significantly ameliorated cardi
149 wild-type AAV2 (wtAAV2) replication but also reporter gene expression from both single-stranded and d
150 d assays, including SMAD-mediated luciferase reporter gene expression, and differentiation of a multi
151 b promoter supports enhanced expression of a reporter gene in sphk2(MZ) embryos compared to wildtype
153 hieve a 110-fold increase in expression of a reporter gene relative to non-replicating controls.
156 arted by the 5 UTR can be transferred onto a reporter gene, indicative that the 5 UTR can solely driv
157 ges were monitored using a novel fluorescent reporter gene, pMitoTimer, that allows assessment of mit
163 s (ULG8), which we have leveraged to express reporter genes in mature male and female gametocytes.
164 nalized virus remained capable of expressing reporter genes while viral replication was blocked.
167 d-type skin grafted onto Fgfbp1 GFP-knock-in reporter hosts and bone marrow transplants from the GFP-
168 using the zeocin resistance gene sh-ble as a reporter in monocistronic and dicistronic constructs, an
170 e mouse in vivo can also regulate its 3' UTR reporter in the liver of another mouse through serum exo
171 ables accurate quantification of fluorescent reporters in complex human iPSC-derived retinal organoid
175 , in applications where a small fluorescence reporter is required or desirable, the choice of fluorop
179 H target tissues using a novel TH-responsive reporter line and found that both alpha- and beta-cells
185 Foxp3-mRFP/cd69(+/-) or Foxp3-mRFP/cd69(-/-) reporter mice and short hairpin RNA (shRNA)-mediated sil
188 y as well as the use of Cldn14-lacZ knock-in reporter mice confirmed increased Cldn14 expression and
190 e, transcriptome analysis using IL-17A(hCD2) reporter mice revealed a similar gene expression profile
193 nts in the epidermis of the hind paws of the reporter mice showed that EGTA and MDL28170 diminished c
195 n sensitization were analyzed using cytokine reporter mice, an adoptive cell transfer model, and gene
196 ated recombination was assessed by using Cre-reporter mice, polymerase chain reaction of genomic DNA,
197 al multiphoton microscopy of DC(GFP)/MC(RFP) reporter mice, we herein provide in vivo evidence that m
198 Using bigenic Gli1-CreER(t2); R26tdTomato reporter mice, we observed increased distance between Gl
201 sts and bone marrow transplants from the GFP-reporter model into wild-type hosts revealed that circul
204 ninvasive imaging of animal subjects bearing reporter-modified intracranial xenografts, we quantitati
205 r electrochemical sensors consist of a redox-reporter-modified protein (the "receptor") site-specific
206 that changing the 3'UTR of a miRNA-targeted reporter modulates translational repression by affecting
209 r chemical structure allows the insertion of reporter molecules and surface-binding agents in specifi
210 trategy, we expressed multiple complementary reporter molecules from the murine Hmox1 locus, includin
211 DMA allows for the detection of redox-active reporter molecules irrespective of their electrochemical
212 e of DCs in renal inflammation using a CD11c reporter mouse line and two mouse lines with DC-specific
213 Immunohistochemical staining in an aromatase reporter mouse revealed that many neurons in laminae I a
216 ng cytosolic Ca(2+), and a transgenic Ca(2+) reporter mouse with Salsa6f targeted to the Rosa26 locus
217 artificial chromosome (BAC)-based lymphatic reporter mouse, where EGFP is expressed under the regula
218 of which selects for translation of viral or reporter mRNAs with 5' untranslated regions that contain
219 dividual isolated cells, we measured knockin reporters, mRNAs, signaling (phosphorylation of extracel
220 ate that endogenous Nur77 is a more specific reporter of Ag-specific signaling events than the common
221 ontrast with previous reports of S100A4 as a reporter of EMT, we discovered that S100A4 is an upstrea
222 nous Nur77 protein expression can serve as a reporter of TCR and BCR specific signaling in human PBMC
223 e used time-lapse microscopy and fluorescent reporters of DNA replication and chromosome positioning
228 60,000 shRNAs using a cell line with a MeCP2 reporter on the Xi and found 30 genes clustered in seven
229 f aggregated silver nanoparticles with Raman reporters on them was synthesized and functionalized to
230 oduce azide, one of the most useful chemical reporters, onto a broad range of bioactive azaheterocycl
232 se models used in research involve knock-in (reporters or recombinases) or gene replacement (e.g., co
233 studying real-time signatures of fluorescent reporters placed on RNAP and DNA in the presence of liga
234 ronJet hereafter) device was used to deliver reporter plasmids (pCMVbeta and pEGFP-N1) into viable ex
235 and developmentally differentiated NKX2-1GFP reporter pluripotent stem cells (PSCs) in vitro to gener
237 ts and subsequently to a single stranded DNA reporter probe bearing a HRP molecule, followed by subst
238 med BC2T) and BC2 nanobody-dye conjugates or reporter protein fusions are evaluated in ELISA, flow cy
239 s results in the in-frame translation of the reporter protein hence the sparse neuronal labeling.
241 ing a full-length, approximately 45-kDa K15P reporter protein is expressed as an approximately 23- to
242 aration and purification of chemical dye- or reporter protein-antibody conjugates is often complicate
243 e that enables bioelectronic measurements of reporter proteins in living cells as an alternative to t
246 el in which the positive and negative energy reporters regulate AGPase catalytic activity via intra-
247 s by >97%, but it did not reduce the KIR2DS2 reporter responses, indicating a beta2-microglobulin-ind
251 approaches using subcellularly targeted FRET reporter sensors have helped define more compartmentaliz
254 eage tracing by using Cdh5cre(ERt2)/Rosa-YFP reporter strategy demonstrated that the CD31-/loVEGFR2lo
257 -binding motif that was supported in vivo by reporter studies, and in vitro by run-off transcription
259 Here, we utilized a loss-of-function HR-reporter substrate to simultaneously monitor HR-mediated
260 ty, prevents the translation of Mos or Ccnb1 reporters, suggesting that MPF is required for their tra
261 OSTs in vivo using a transgenic glycoprotein reporter system and performed glycoproteomics on endogen
262 Here we develop a 4-colour fluorescence reporter system at the single-virus level, combined with
264 lfides were investigated using a fluorescent reporter system in order to optimize linker stability fo
267 RNAs, and a newly developed luciferase-based reporter system to quantitatively determine the importan
268 ed on this data, using a newly developed gfp reporter system we validate an Hfq-dependent mRNA repres
270 transformed cells programed with fluorescent reporter systems and by quantitative cell imaging, the c
271 us genes cannot be faithfully represented by reporter systems in which, at least in metazoans, the ob
273 this observation, we biochemically isolated reporter-tagged Mbp mRNA granules from primary cultured
274 anscription factor activated luciferase/eGFP reporter (TFAR) cassettes to neonatal mice enabling long
275 lia, resulting in changes in transcriptional reporters that are dependent on Drosophila AP-1 (dAP-1)
276 ton microscopy with two different activation reporters, the FRET-based calcium biosensor Twitch1 and
278 eq, which uses a Cre recombinase interaction reporter to intracellularly fuse the coding sequences of
279 re, we use a DNA-based, fluorescent chloride reporter to measure lysosomal chloride in Caenorhabditis
280 es, we generated a novel class of FRET-based reporter to monitor conformational differences correspon
282 ver, we demonstrate the suitability of these reporters to measure differences in DRC in multiple path
283 re, we use behavioral assays and fluorescent reporters to show that axonal fusion enables full recove
285 , termed Specific High-Sensitivity Enzymatic Reporter UnLOCKing (SHERLOCK), to detect specific strain
287 f human embryonic kidney 293 cells with this reporter vector increased luciferase activity upon stimu
288 These results demonstrate that our TREM2 reporter vector is a novel tool for monitoring the TREM2
289 d enrichment of HIV-1 infected cells using a reporter virus expressing a surface reporter for gentle
290 t and a ZIKV C-prM-E cell line that produces reporter virus particles upon transfection with a GFP re
292 l integration, the hTERT, but not the mTert, reporter was stringently repressed in telomerase-negativ
294 e efficacy of the developed, fully synthetic reporters was demonstrated by the identification of nove
298 selection of promoter regions for transgenic reporters, we assembled and annotated the M. lignano gen
299 amethasone-mediated transactivation of a GRE reporter while still maintaining its actin-binding activ
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