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2 ds detected in RISC by AGO2 immuno-isolation represented 16% of total 5-phosphorylated guide strands
9 e ease of use and abundant access to tCS may represent a broad-reaching and important advance for fut
11 at deficits in IP3-mediated Ca(2+) signaling represent a convergent hub function shared across the sp
13 clude that alterations of KDM family members represent a disease-driving mechanism and an explanation
14 nondirection-selective ON-OFF RGC types that represent a distinct set of feature detectors in the mou
15 sing peptides and other affinity ligands may represent a general strategy to increase their therapeut
16 presenting to the emergency department (ED) represent a heterogeneous population comprised of all ag
20 tion changed, however, are still unclear and represent a major challenge to our understanding of glac
21 therapies, and heavy chain (Hc) heterodimers represent a major class of bispecific drug candidates.
22 duced through anaerobic microbial metabolism represent a major energy source for the host colonic epi
23 t it is unclear whether 1 semen sample could represent a man's long-term average values in epidemiolo
25 stochemistry using the CM2B4 antibody alone, represent a more aggressive subtype that warrants closer
29 ore through aromatic hydroxylation reactions represent a new domain for high-valent bis(mu-oxido)dime
30 Floral temperature patterns may therefore represent a new floral cue that could assist pollinators
35 Stem/progenitor cell-based interventions represent a novel class of potential therapies for retin
37 l injury via mitochondrial actions and could represent a novel therapeutic strategy to minimize the d
40 weed-associated microorganisms were shown to represent a potential source of antimicrobial compounds
43 hat increased cerebrovascular resistance may represent a previously unrecognized contributor to Alzhe
44 m, particularly in BRAF-mutant melanoma, and represent a promising lead for the development of new an
45 ice reconstituted with a human immune system represent a promising tool for translational research as
47 is unique to a population and these changes represent a shift in the primary population in the monit
48 to prevent serious bacterial infections, and represent a significant advancement toward broader pract
51 late Eocene to early Oligocene, and does not represent a single response to a rapid decline in atmosp
55 findings suggest that targeting of GPX4 may represent a therapeutic strategy to prevent acquired dru
58 lic enzyme indoleamine 2,3-dioxygenase (IDO) represent a vanguard of new immunometabolic adjuvants to
60 ignaling pathway within the glomerulus, thus representing a new potential glomerulus-specific targete
61 bin homo-oligomer to form a ternary complex, representing a novel mode of regulation of G protein-cou
62 currently available GLP-1 receptor agonists, representing a potential treatment option for such patie
63 lements and are environmentally benign, thus representing a promising choice for sustainable and safe
65 the limbal basement membrane, with LN-alpha5 representing a signature component specifically produced
66 ites and CMOS photonics platform, while also representing a useful technological tool for the control
67 nesis and the progression of prion diseases, representing a valid tool for distinguishing different f
68 earch has unequivocally shown that psoriasis represents a bona fide T cell-mediated disease primarily
72 directly influence corneal biomechanics and represents a clinically relevant factor that needs furth
74 tracellular space (apoplast) of plant tissue represents a critical battleground between plants and at
76 past decade, but it is unclear whether this represents a decline in S. aureus infections overall.
80 se results suggest that germ plasm targeting represents a fitness strategy adopted by some retrotrans
81 markers indicated that c.254-649T > G CLRN1 represents a founder allele that may significantly contr
82 This detailed experimental comparative study represents a fundamental step to understand the spin dyn
84 e is a common cause of visual impairment and represents a highly heterogeneous group of conditions.
85 ngs suggest that the dual-activity inhibitor represents a highly promising lead compound for the deve
87 erto unknown Del-1 function in the HSC niche represents a juxtacrine homeostatic adaptation of the he
88 bye screening layer of an electrolyte, which represents a key physicochemical surface property in var
91 to identify mutation carriers among probands represents a lost opportunity to prevent cancer in unsus
92 liana, the AP2-type AP2 transcription factor represents a major A-function protein, but how the A-fun
93 integrity and excellent tissue compatibility represents a major breakthrough in this field and a prom
100 th three substrates revealed that the enzyme represents a new class of zinc-binding flavin-dependent
101 attachment of DNA to metal surfaces but also represents a new direction for the site-specific attachm
103 mpasses a genus-level sequencing effort that represents a new type of model system driven not only by
105 for MPS-I at a very early stage in life and represents a novel model to test UCB-based transplantati
107 ults indicate that PDAC extracellular matrix represents a nutrient reservoir for tumour cells highlig
108 aling dynamics determine cell physiology and represents a paradigm shift from descriptive to predicti
116 dly, fully translatable to industry and thus represents a significant advance in the development of c
118 ain chemical reactions: the microscale model represents a single fiber cross-section; the macroscale
122 o recruit host CRL4 (DCAF1) E3 ligase, which represents a target for novel anti-human immunodeficienc
124 acts depth from two different retinal images represents a tractable challenge in sensory neuroscience
125 pose that spinal cord regeneration in geckos represents a truncation of the restorative trajectory ob
127 ith the treatment of the underlying disease, represents a valid approach that can improve the pulmona
130 stem from aflatoxin exposure, indeed likely represents AFB1 exposure, possibly combined with other e
134 eed within 10 min at room temperature, which represents among the mildest conditions reported for C-H
136 oupling reactions using alkynyl nucleophiles represent an attractive approach for the incorporation o
138 are complicated theories where limit cycles represent an idealized Red Queen, and therefore cannot b
139 ew will argue that neural-glial interactions represent an important avenue for advancing our understa
140 Histone lysine methyltransferases (KMTs) represent an important class of epigenetic enzymes that
144 sampling is less noise and more processing, representing an 'evolutionary adaptation' to generate a
145 approaching objects from behind, potentially representing an adaptation compensating for limited neck
147 of lipid mediators, counteract this effect, representing an attractive target for therapeutic interv
149 related to the FDA-approved drug memantine, representing an uncompetitive/fast off-rate antagonist o
151 cable to the treatment of other diseases and represents an advancement toward the development of smal
153 composed of the proteins NP, VP35, and VP24, represents an attractive target for drug development; ho
158 tion and that SIAH-mediated Axin degradation represents an important feed-forward mechanism to achiev
159 fore, the modulation of interdomain dynamics represents an important mechanism during antibody matura
160 d support the notion that abortive infection represents an important mechanism underlying progressive
162 on of CA and the peptide SP1 (CA-SP1), which represents an intermediate during maturation of the HIV-
163 creation of new prochlorosin structures and represents an intriguing mechanism by which natural prod
167 is necessary to characterize how stimuli are represented and how this representation is used in the e
168 artly to the unique mixture of ionic species represented and their highly organized assembly in the c
169 xtraction mechanism for membrane perforation represents another distinct process that contributes to
172 that both PGC1alpha and capsid assembly may represent attractive targets for the development of anti
173 ey, ranging from 0 to 100, with higher score representing better self-reported health) at 6 months.
174 Among the US primary prevention population represented by 3416 individuals in NHANES, the median we
176 ognostic role of host antitumour immunity as represented by baseline quantities of TILs in patients w
179 terminally truncated amyloid-beta42 species, represented by pyroglutamylated amyloid-beta11-42, were
180 l meridional gradient in SSTs, which are not represented by the AMO index value, but which may lead t
185 onocyte-derived dendritic cells (moDCs) that represent classical antigen-presenting cells and we aime
190 c in multiple cellular assays and cell types representing different targets from a number of therapeu
191 uron classes connecting the AOTU, BU, and EB represent discrete lineages, genetically and development
193 often be described by a network, with nodes representing economic entities and edges their interdepe
194 ng only 3.7% as "frail." The RAI-C and RAI-A represent effective tools for measuring frailty in surgi
199 transformed to 0 to 100, with higher scores representing greater migraine burden on functioning).
202 c resonance imaging (MRI) is hypothesized to represent impaired drainage of interstitial fluid from t
203 the promiscuity of small molecule inhibitors represent important challenges faced by current anti-AXL
204 cation gaps that persist into mitosis likely represent important threats to genome stability, but exp
207 enome Project studies, is significantly over-represented in human CD56(bright) cells, by gene set enr
209 brin(ogen) deposition was significantly over-represented in MS compared to control cases in all compa
212 o 37 734) excess acquisitions, respectively, representing increases of 53% (95% CI, 30% to 80%) and 4
213 on and cholesterol efflux do not necessarily represent inter-dependent events, but MafB is broadly in
214 hil-associated inflammasome activation might represent interacting pathways in patients with SA.
218 ian 2; quartiles 1-3 per map), although this represented LR in only n=7 out of 50 (14%): here, rotati
219 sformation processes such as denitrification represent major sources of the potent greenhouse gas nit
221 ere extremely diverse, without any clonotype representing more than 2% of the overall TCR population.
223 dimensionless parameter combinations, which represent myosin-dependent contractility, a characterist
226 tumor initiation or progression in smokers, representing novel therapeutic targets for breast cancer
227 use of vague generic names in trade records represent one of the most insidious impediments to seafo
228 Mapping whole-brain activity during behavior represents one of the biggest and most exciting challeng
230 600E mutations were much less common in SBA, representing only 10.3% (3 of 29) of BRAF-mutated cases.
232 and propensity to form toxic oligomers, they represent particularly attractive targets for antibody t
233 n whole blood samples from 150 participants, representing patients in the upper and lower quartile of
234 e skin can be used to modulate touch and may represent peripherally available drugs to treat tactile-
238 n and extraterminal domain inhibitors (BETi) represent promising therapeutic agents for metastatic me
241 and improvement of endothelial NO production represent reasonable therapeutic strategies in addition
243 lyses suggested that a cluster of mutations, representing roughly 20% of the patient population with
245 it remains unclear whether these cases truly represent sexually antagonistic coevolution; alternative
247 ogether, our findings demonstrate that PGCCs represent somatic equivalents of blastomeres, the most p
248 lts demonstrate that neurons in the human EC represent space with an enhanced flexibility relative to
249 focal lesions affect the brain's ability to represent stimuli and task states, and that information
252 the reproductive numbers of the disease that represent the average number of secondary infections pro
253 rocedures, hospital market consolidation may represent the best value proposition: better quality of
258 hree-dimensional quadrant model was built to represent the structural origins of regio- and enantiose
259 ented and analyzed as a network, where nodes represent the units of the network and edges represent c
260 on (zwt+7 mo), and conditional measures that represented the change from the preceding time] and were
261 N-linked glycosylation site; and 2 variants represented the head domain, 1 complete and 1 truncated.
262 titial nephritis, as cause of renal failure, represented the only predictive factor for MGUS developm
263 t histone genes on chromosome 6, potentially representing the chromatin architecture at the histone l
265 work, we use a nonlinear mathematical model representing the course of an influenza infection to exp
266 to properly bi-oriented sister kinetochores, representing the final outer kinetochore component recru
267 nthropologists to be the "first profession", representing the first institutionalized division of lab
268 mics were initially biased toward the choice representing the highest sum/mean before being redirecte
269 an before being redirected toward the choice representing the maximal reward (i.e., initial dip).
270 seen at PML-IRIS, with contrast enhancement representing the most frequent sign of inflammation (90%
271 dient and a mean easterly trade wind anomaly representing the multidecadal acceleration of the trade
272 ailable membracoid mitogenomes and outgroups representing the other two cicadomorphan superfamilies s
273 resence of an association and the parameters representing the pathogenicity of each variant and the m
274 decades of transgenic crops, with each case representing the responses of one pest species in one co
275 99 previously diagnosed cases proportionally representing the spectrum of diagnoses seen in the labor
277 3.1 (P311), a conserved RNA-binding protein, represents the first documented protein known to stimula
279 e best of our knowledge, this transformation represents the first example of catalytic couplings betw
280 he hydrogen-bond-based resorcinarene capsule represents the first man-made enzyme-like catalyst that
281 ionalization in good to excellent yield, and represents the first step towards a general transition m
282 tions in the three-band Hubbard model, which represents the local electronic structure of the copper-
285 ritonavir-boosted protease inhibitors (bPIs) represents the only available option after first-line fa
286 e intolerance, thereby confirming that DHHC7 represents the principal PAT for Glut4 and that this mec
292 t roots in two of four Douglas-fir families, representing three- and fourfold increases (+ c. 4 mug e
295 t lake sturgeon in the Detroit and St. Clair represent two semi-independent populations that could re
297 he cGERGM on a testbed of simulated networks representing various commonly observed brain architectur
298 haracteristics of the Bagel Sign potentially represent venous engorgement and/or acute blood products
299 /BR follow characteristic sigmoid plots when represented versus redox potential suggesting that all c
300 ponses (MMRs) to equivalent pitch deviations representing within-category and between-category differ
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