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1 ene embedded in the region was significantly repressed.
2 on patterns, whether the genes are active or repressed.
3 R1 is absent and genes under its control are repressed.
4 gh translation efficiency were more robustly repressed.
5 involved in cell migration and invasion are repressed.
6 iption factor and the associated promoter it represses.
13 the plant immune system by transcriptionally repressing a subset of the jasmonic acid (JA) hormone si
15 lant growth and stress regulator CPR5, which represses accumulation of SA, favors growth in physiolog
16 sence of inducer, promoter activity is fully repressed; addition of inducer rapidly increases gene ex
19 maintenance of floral stem cell fate, not by repressing AG transcription, but by antagonizing AG acti
20 stic conservation between fission yeast PAF1 repressing AGO1/small interfering RNA (siRNA)-directed s
22 d that PAX6 binds promoters and enhancers to repress alternative islet cell genes including ghrelin,
23 omogenic path, suggesting that Pax2 normally represses an otherwise inevitable transition between sis
24 that nitric oxide primarily protects mice by repressing an interleukin-1- and 12/15-lipoxygenase-depe
26 luding the ability to switch rapidly between repressed and activated target gene expression states, i
27 for transmission, including translationally repressing and protecting mRNAs needed to establish the
29 onal repressors: male-biased BCL6, which was repressed, and female-specific CUX2, which was induced.
32 Aside from secondary metabolism, ScmR also represses biofilm formation and transcriptionally activa
34 up ('dark' shadow enhancer) that is normally repressed but becomes active in the absence of the other
36 ram-negative pathogens and whose activity is repressed by a flanking substrate-binding leucine-rich r
39 or assembling an effective TSS as tTA can be repressed by addition of tetracycline to the diet at lar
43 Male-biased genes activated by STAT5 and/or repressed by CUX2 were enriched for early cGH repression
53 sing FGF13 and miR-504, is transcriptionally repressed by p53, defining an additional negative feedba
58 by an alternative promoter whose activity is repressed by the liganded estrogen and androgen receptor
59 biotype vibrios, transcription of vieSAB is repressed by the quorum sensing regulator HapR, which is
60 he JAZ proteins in the absence of JA, but de-repressed by the SCF(COI)(1) complex on perception of JA
61 We further showed that Tnc expression is repressed by the transcription factor Nkx2-1, a well-est
62 ly identified Zhx2 targets that appear to be repressed by Zhx2, Mup genes are positively regulated by
63 found that the mRNAs' translation rates were repressed, by up to 530-fold, when mRNA structures overl
65 study demonstrated MART-10 could effectively repressed CCA growth in vivo without inducing obvious si
68 inhibits Pol III binding to DNA via inducing repressed chromatin and is a determinant for the Pol III
70 uld write epigenetic marks associated with a repressed chromatin state (G9A, SUV39H1, Kruppel-associa
71 work reports that both derepressed and hyper-repressed chromatin states in animals can be transmitted
73 A methylation activates COL2 expression, and repressing COL2 in cultivated cotton delays flowering.
74 ted the proliferation of colon cancer cells, repressed colon CSCs and prevented xenograft growth.
75 provide evidence that ZEB1 binds not only to repress critical genes involving in pigment synthesis, m
78 demonstrate that NCoR1 plays a major role in repressing developmental maturation of the intestines.
79 f several genes that are usually selectively repressed ("disallowed") in beta cells, including Slc16a
81 chromatin structure, elucidating subtypes of repressed domains that are uniquely predictive of divers
85 the regulation of VM and suggest that miRNAs repressed during EMT, in addition to suppressing migrato
88 n ECs, overexpression of let-7 by adenovirus represses EC proliferation, migration, and networking in
89 similar role in chick and mouse in directly repressing ectodermal cadherin genes to contribute to th
90 e, and a DAXX-SETDB1-KAP1-HDAC1 complex that represses endogenous retroviruses independently of ATRX
92 muscular lipid metabolism and body weight by repressing estrogen receptor alpha (ERalpha) expression.
93 hat they can act as antisense transcripts to repress expression levels of sense genes from the opposi
94 ulated genes and that BR signalling can also repress expression of RD26 and its homologues and inhibi
96 in highly mesenchymal SUM159 TNBC cells can repress expression of the epithelial transcription facto
97 ing factors to gene promoters to activate or repress expression, however, the mechanisms by which fac
100 nscription factor Blimp-1 (encoded by Prdm1) repressed expression of the gene encoding cathepsin S (C
101 on of a subset of gynecological cancers with repressed expression of the polyubiquitin gene UBB, whic
105 pp promotes Dachs activity by simultaneously repressing Fat via posttranslational modification and re
107 1 (PEP1), two orthologous MADS-box TFs that repress flowering and confer vernalization requirement i
110 o binds osteoblast-produced R-spondin, which represses Fzd degradation by activation of LGR4, an R-sp
114 y, but DREAM completely loses its ability to repress genes in G0/G1 while all remaining subunits, inc
116 ecruitment of transcription factors (TFs) to repressed genes in euchromatin is essential to activate
117 ssed gene and Gdnf and Gfralpha1 as androgen-repressed genes in UGS, thus establishing reciprocal reg
118 iptional activation and repression, with Wnt-repressed genes often lacking canonical Tcf DNA binding
119 repression in a significant fraction of heat-repressed genes suggests that repression of these genes
121 developmental potential in immature INPs by repressing genes encoding neuroblast transcriptional act
122 gingivalis to dysregulate innate immunity by repressing gingipain-associated degradation of interleuk
123 , and that an increase in cytoplasmic TDP-43 represses global protein synthesis, an effect which is r
125 ed normal chow to concentrated ambient PM2.5 repressed hepatic transcriptional regulators involved in
126 that mutation of the gene encoding HSP90beta represses hepatocyte differentiation during the formatio
127 ulates expression of cholangiocyte genes and represses hepatocyte genes in undifferentiated progenito
130 Taken together, our findings indicate that repressed IFN signaling in TNBCs with CSC-like propertie
131 These mesenchymal/CSCs have a significantly repressed IFN/STAT gene expression signature and an enha
132 f3 gene may be either reversibly elevated or repressed in adult animals by oral administration of tet
133 se transcriptase (hTERT) gene, which remains repressed in adult somatic cells, is critical during tum
136 hatase PTPRO is frequently transcriptionally repressed in cancers and signifies poor prognosis of bre
142 but not the mTert, reporter was stringently repressed in telomerase-negative human cells in a histon
143 ric BACs, the mTert promoter became strongly repressed in the human genomic context, but the hTERT pr
145 estingly, without this enzyme S. aureus were repressed in their ability to secrete cytolytic toxins,
147 hypermethylated and silenced, while COL2D is repressed in wild cottons but highly expressed due to me
148 We propose that the HIRA chaperone complex represses incoming naked viral DNAs through chromatiniza
149 multimeric complexes with host proteins that repress innate immune responses and force host cells int
151 induction of hypoxic responses caused CHD by repressing Isl1 and activating NK2 homeobox 5 (Nkx2.5),
154 nition motif 1 (RRM1) in SRSF1 binds PP1 and represses its catalytic function through an allosteric m
156 ing H3K9me2/3 at the CIITA promoter, thereby repressing its expression through NO and p38 MAPK activa
159 s its expression, but we observed that SIRT1 repressed LEF1 protein and mRNA expression, ultimately r
161 rm lacking the N-terminal CXXC-domain, which represses Lhb gene expression directly and does not cata
162 nging of apoplastic H2O2 by potassium iodide repressed lignin formation, in line with peroxidases act
164 DNA elements that recruit PcG complexes to a repressed locus also encode transcriptional enhancers th
165 e propose that L. monocytogenes uses CadC to repress lspB expression during infection to avoid LpeA e
167 In budding yeast, Rph1 transcriptionally represses many DNA damage or autophagy-related gene expr
171 4c can form a regulatory loop with Notch1 to repress muscle development, and this result expands our
174 tomics, here we report that DnrF selectively repressed nitrate reductase (nap) genes, preventing furt
176 n of Myt1l in primary postmitotic neurons de-repressed non-neuronal programs and impaired neuronal ge
177 a strategy in which AvrPtoB targets NPR1 and represses NPR1-dependent SA signaling, thereby subvertin
178 embrane-associated protein Basp1, thereby de-repressing nuclear factors WT1, Esrrb and Lin28a (Lin28)
180 each directly associating with either EBNA3-repressed or EBNA3-activated genes, but not with both.
181 e luciferase reading frame, the XDP variants repressed or enhanced transcription, respectively, to an
182 ication influences gene expression by either repressing or activating genes, depending on the specifi
183 enes by binding to specific sites in DNA and repressing or activating transcription in response to st
184 P-cadherin We also show that Snail2 and Zeb2 repress P-cadherin transcription in the primitive streak
190 ates with IEC barrier formation and butyrate represses permeability-promoting claudin-2 tight-junctio
192 agent or in combination with carfilzomib, in repressing phosphorylation of 4E-BP1 and the protein lev
193 ent biosynthesis or translation are known to repress photosynthesis-associated nuclear genes via retr
194 depletion of HP1gamma in PCa cells not only repressed proliferation and induced apoptosis but also i
197 ale germ cells, which suggests that CNVs may repress recombination by altering chromatin structure in
198 ally driven effects are strongly enriched in repressed regions and near transcription start sites, wh
199 r-enhancers, bivalent promoters and Polycomb repressed regions, and identify additional patterns whos
201 ow that FGF13 1A is a nucleolar protein that represses ribosomal RNA transcription and attenuates pro
202 ggest that cancer cells re-express PIWIL3 to repress RNAi through miRNAs and thus open a new opportun
203 s secrete exosomes containing miR-206, which represses Rrbp1, a master regulator of collagen biosynth
205 SWI/SNF chromatin remodeler subunit, BAF60, represses seedling growth by modulating DNA accessibilit
206 Mechanistically, we determined that miR-27 represses several known as well as previously uncharacte
207 found FMRP binds shrub mRNA (human Chmp4) to repress Shrub expression, causing overexpression during
209 transcription factor Zeb2 cell-autonomously represses Smad signalling to limit midbrain dopaminergic
211 ing RNA (lncRNA), SMN-antisense 1 (SMN-AS1), represses SMN2 expression by recruiting the Polycomb Rep
218 onversely, the mouse genomic context did not repress TERT transcription until late during differentia
221 s mutation impairs the ability of lamin A to repress the anti-adipogenic miR-335, providing a potenti
222 AP2-type REPRESSOR OF B-FUNCTION (ROB) genes repress the B-function (but not the C-function) in the f
223 induced by the same stimuli that dominantly repress the development of other, non-specific T cell li
224 has been reported to post-transcriptionally repress the DNA MMR gene mutS in stationary phase, possi
225 status arginine deiminase (ArcA) was able to repress the expression and production of several well-kn
227 ivation restores redox balance, but fails to repress the inflammatory effect of TGF-beta1 which is su
228 conserved SET/NAP domain, and exacerbate and repress the transactivation of the AR/AR-V7 target genes
229 study indicates that knockdown of IRE1alpha repressed the expression of beta-catenin, a key factor t
232 r pharmacological inhibition of CDK6 in mice repressed the growth of Hh-associated medulloblastoma an
234 he naive state, polycomb recessive complex 2 repressed the IRAK-M promoter, allowing low levels of ex
236 in treatment in mice infused with Ang II and repressed the metformin-mediated reduction of cardiac hy
237 did not reactivate efficiently ex vivo kLANA repressed the MHV68 promoter for ORF50, the gene that en
238 ible factor 1 alpha subunit (HIF1A) directly repressed the MIR34A gene in p53-defective CRC cells, wh
240 dopsis uORF and its maize (Zea mays) homolog repressed the translation of the main open reading frame
243 tant virus, we found no evidence that miR-H2 represses the expression of ICP0 or other lytic genes in
246 show that, in addition to GATA3, FoxM1b also represses the mammary luminal differentiation marker Fox
247 e find that LSD1, via H3K4me1 demethylation, represses the master regulator of osteoblast differentia
249 of hermaphroditic cell identity tra-1, which represses the transcription of dmd-3 in hermaphrodite PH
252 findings highlight the function of PRDM13 in repressing the activity of bHLH transcriptional activato
254 th while antagonizing cellular senescence by repressing the expression of cyclin-dependent kinase inh
255 sses in part by binding to the promoters and repressing the expression of GIGANTEA and PHYTOCHROME IN
256 , p62 delayed the degradation of MYC mRNA by repressing the expression of let-7a and let-7b, thus pro
257 adened DNA-recognition specificity, directly repressing the expression of the gene encoding the trans
258 ition (EMT) of lung cancer cells by directly repressing the expression of transcription factor Slug,
259 ath of mothers of cells programmed to die by repressing the gene egl-1, which encodes a proapoptotic
261 an improve outcomes in glomerular disease by repressing the reactivation of developmental pathways.
263 hich sequesters Nrf2 in the cytosol, thereby repressing the transcription of Nrf2-dependent antioxida
264 tors often bind cooperatively to activate or repress their target genes in a cell type-specific manne
265 ty with which members of the KRAB-ZFP family repress their targets and identify an additional layer o
266 monstrated that, upon CREB activation, HDAC2 represses thrombospondin-1 (TSP1), a potent angiogenesis
271 t a model in which DnaA and Rok cooperate to repress transcription of yxaJ, the yybNM operon and the
272 n multimodal fashion to directly activate or repress transcription, in a context- and partner-depende
274 rmed by the SUV39 histone methyltransferases represses transcription from repetitive DNA sequences an
275 mplex (DCC), which specifically binds to and represses transcription from the hermaphrodite X chromos
276 x-turn-helix-like structure and specifically represses transcription initiation from host RNAP-depend
277 is an emerging epigenetic enzyme that mainly represses transcription of target genes via symmetric di
279 6A)-infected cells with actinomycin D, which represses transcription, restores SG assembly suppressio
280 mitogenic epidermal growth factors (EGFs) by repressing transcription of the EGF maturation factor rh
285 ite of sRNAs, including the RaiZ sRNA, which represses translation of the hupA mRNA, and the Legionel
287 miR-23b cluster or miR-125a-5p significantly repressed tumour growth in a highly aggressive NSCLC cir
288 ly, Id proteins specify cardiac cell fate by repressing two inhibitors of cardiogenic mesoderm format
292 expression in classical biotype V. cholerae repressed vieSAB transcription by binding to its promote
295 we named REPRESSOR OF VERNALIZATION1 (RVR1), represses VRN1 before vernalization in Brachypodium dist
298 hat activates brown fat-specific genes while repressing white fat and muscle-specific genes in adipoc
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