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1 x repressor CzrA (chromosomal zinc-regulated repressor).
2 e known to be repressed by a transcriptional repressor.
3 for PRMT5's proposed role as a transcription repressor.
4 ng the formation of the GLI3 transcriptional repressor.
5 Notch signal, RBPJ acts as a transcriptional repressor.
6 s (SaPIs) by binding to the SaPI-encoded Stl repressor.
7 ed one such protein, Zfp36, as a translation repressor.
8 the -44 region, where it acts as a splicing repressor.
9 NA-binding domain-containing transcriptional repressor.
10 RMINAL FLOWER1 (FvTFL1) as the causal floral repressor.
11 tors (TCF) and kept silent by Groucho/TLE co-repressors.
12 fic gene expression, either as activators or repressors.
13 the result of repression by transcriptional repressors.
14 r degradation of the Aux/IAA transcriptional repressors.
15 ighly conserved surface for interaction with repressors.
16 d the regulation of Gli2/Gli3 activators and repressors.
17 al novel uncharacterized MYB transcriptional repressors.
18 ly conserved, class-specific transcriptional repressors.
19 thologue Snf1 and downstream transcriptional repressors.
20 tion as either transcriptional activators or repressors.
21 protein interactions with co-activators and -repressors.
22 tes, and also by mRNA-specific translational repressors.
23 ression, while OsCPP5 and OsNIN-like2 act as repressors.
24 the specific deletion of nuclear receptor co-repressor 1 (NCoR1) in T cells causes excessive negative
26 ttranslational regulation of the translation repressor, 4E-BP (eukaryotic translation initiation fact
30 hr of immature INP birth, downregulation of repressor activities alleviates Rpd3-mediated repression
31 nd revealed that these have both inducer and repressor activities, possibly due to competitive bindin
32 FPs that inhibit ABA response have intrinsic repressor activity in a heterologous system, which does
34 methylation of the aryl hydrocarbon-receptor repressor (AHRR) locus, which is observed in blood and s
35 DNA methylation in aryl-hydrocarbon receptor repressor (AHRR), a sentinel epigenetic biomarker of exp
36 action of LIMR and aryl-hydrocarbon receptor repressor (AHRR), and promoted protein expression as wel
37 on enhancing induction of Cyp1b1/CYP1B1, AhR repressor (Ahrr/AhRR) and TCDD-inducible poly(ADP-ribose
38 ne response in the lung epithelium and whose repressor, AHRR, has recently been implicated in smoking
43 matin at DSBs, limits binding of the L3MBTL1 repressor and promotes 53BP1 binding, while limiting end
45 henotypes in line with TgTFL1 being a floral repressor and TgSOC1-like2 being a floral activator in t
46 ions in turn reduce the affinity for the Stl repressor and the capacity to induce the SaPI cycle.
47 ays, indicating that the balance between GLI repressors and activators is altered in affected subject
49 geting mRNA, and zinc finger transcriptional repressors and CRISPR-Cas9 methods aiming to reduce tran
50 ndent of the Snail family of transcriptional repressors and down-regulation of Drosophila E-cadherin
52 1, falls into a class of MYB transcriptional repressors and, accordingly, higher expression of this g
53 This C-terminus binds to the Groucho/TLE co-repressor, and also to the Chip/LDB1-SSDP enhanceosome c
55 present together in an approximately 1.9-MDa repressor assembly that quantitatively incorporates its
56 response results from saturation of the LacI repressor at low inducer concentrations and dilution of
57 ely mimic those of deleting the fetal globin repressor BCL11A, implicating BCL11A in the function of
60 ntire MeCP2 protein sequence, the DNA and co-repressor binding domains alone are sufficient to avoid
64 ously unidentified role that transcriptional repressor Blimp1 plays in the control of breast cancer i
65 xpression of the zinc finger transcriptional repressor Blimp1/PRDM1 is essential for the establishmen
67 iors that are well-suited to transcriptional repressors but perhaps incompatible with precise activat
68 can be converted into an As(III)-responsive repressor by introduction of an additional cysteine that
70 he developmentally regulated transcriptional repressor Capicua (CIC) suppresses invasion and metastas
73 ependent photoreceptors, the transcriptional repressor CarH, is widespread in bacteria and mediates l
76 erating mice in which both Apc and ER stress repressor chaperone Grp78 can be conditionally deleted f
81 s through engagement of the REST-coREST-LSD1-repressor complex and altered histone marks at the p21 p
82 ine-specific histone demethylase 1 (LSD1) co-repressor complex associates with the hTERT promoter in
83 eal for the first time role of TRF2 in REST- repressor complex mediated transcription repression.
84 chment of the OGT-containing transcriptional repressor complex mSin3A-HDAC1 at the proximal promoter
86 TRalpha1PV to recruit NCOR1DeltaID to form a repressor complex relieved the deleterious actions of TR
87 omoter and recruits the NuRD transcriptional repressor complex to de-acetylate H3K9 and repress RNA p
88 active transcription mark and recruits a co-repressor complex to regulate gluconeogenic gene express
91 DING REPRESSOR FACTOR1 (HBF1) and HBF2, form repressor complexes that reduce Hd3a and RFT1 expression
92 a promiscuous transactivator, and it blocks repressor complexes to enable viral gene transcription.
93 with its E3 ligase activity, and it disrupts repressor complexes via protein-protein interaction to e
94 es, including intracellular Notch, or within repressor complexes, including the antagonist Hairless.
95 he yeast Saccharomyces cerevisiae, the Opi1p repressor controls the expression of INO1 via the Opi1p/
96 f OR stabilization; (2) colocalizes with the repressor CoREST (also known as RCOR1) and histone deace
100 c inhibition of DNA binding by the Zn efflux repressor CzrA (chromosomal zinc-regulated repressor).
101 uding the E26 transformation-specific family repressors Drosophila melanogaster Yan and its human hom
102 ChIP-seq database identified transcriptional repressor E2F6 as a possible negative regulator of MDM2
103 analyses, we show that the binding of REST (repressor element 1 (RE1) silencing transcription factor
104 that NED of PCa requires down-regulation of repressor element-1 silencing transcription factor (REST
105 suggests that subsequently, transcriptional repressors ensure the transition of progenitors to matur
106 of CLOCK:BMAL1 activity by coactivators and repressors establishes the approximately 24-h periodicit
107 growth factor independent 1B transcriptional repressor, ETS variant 6, ecotropic viral integration si
109 peculate that similar 'many-but-one' lineage repressors exist for other cell fates; such repressors,
112 experiments reveal increased binding of the repressor factor RE1-silencing transcription (also known
113 er, additional bZIPs, including Hd3a BINDING REPRESSOR FACTOR1 (HBF1) and HBF2, form repressor comple
114 Polycomb to mediate silencing of the floral repressor FLOWERING LOCUS C (FLC) during the process of
115 We further investigate known transcriptional repressors for terminal muscle differentiation, namely Z
116 nding partners, including transcriptional co-repressors (for example, the NCoR/SMRT complex), transcr
119 ssue development and repair however, Musashi repressor function must be dynamically regulated to allo
120 rthermore, inhibition of the transcriptional repressor function of BCL6 in the presence of IM and IFN
121 ken together, these studies define a crucial repressor function of Sf1 SUMOylation and Dax1 in the ph
122 volutionary conservation of the dopaminergic repressor function of Zic proteins and show that it is a
123 sites in FoxM1b serve as a regulator for its repressor function, and they provide insights into how F
125 FPs were fused to either the transcriptional repressor, G9a, which promotes histone methylation or th
126 lowed by MS, we identified a transcriptional repressor, GATA zinc finger domain-containing 2B (GATAD2
128 rase (gp29), the endolysin (gp31), the phage repressor (gp47), and six proteins of unknown function (
131 This is accomplished because the SaPI Stl repressors have acquired different domains to interact w
133 mutation in the gene for the transcriptional repressor histone deacetylase 4 (HDAC4) is associated wi
134 th the levels and activity of the epigenetic repressor, histone methyltransferase enhancer of zeste h
137 ing Th1 effector commitment, T-bet acts as a repressor in differentiated Th1 cells to prevent abberan
139 4 (Vgll4) functions as a transcriptional co-repressor in the Hippo-Yes-associated protein (YAP) path
140 n eudicots but also functions as a flowering repressor in the vernalization pathway of Brachypodium a
143 ot apical meristem, the expression of floral repressors in tulip is suppressed by increased ambient t
144 repressors exist for other cell fates; such repressors, in combination with lineage-specific activat
145 ic acid and by a NadQ family transcriptional repressor, indicating that these organisms prioritize th
146 ar, JunB limits the expression of the subset repressor IRF8, and impedes access of JunD to regulatory
147 R/NOT gates) are encoded in pools where each repressor is fused to all permutations of input promoter
148 ally stimulates the lytic promoters while CI repressor is still present, stimulating the level of Cro
149 L, ATF3, a stress-responsive transcriptional repressor, is down-modulated in skin cancer stromal cell
153 Using a coarse-grained model of DNA and lac repressor (LacI) in the Escherichia coli nucleoid, simul
155 es can interact with the SaPIbov1 Stl master repressor, leading to derepression and mobilization.
156 structurally distinct dUTPases bind the same repressor led us to speculate that dUTPase activity may
158 el binding motif for the SOS transcriptional repressor LexA, and we use this motif to characterize th
159 lacking the zinc-responsive transcriptional repressor Loz1 with the goal of identifying metabolic pa
160 oding two GH/STAT5-regulated transcriptional repressors: male-biased BCL6, which was repressed, and f
162 and spatiotemporal dynamics of a GFP tagged repressor, Mig1, from a paradigm signaling pathway of Sa
163 its interaction with the nuclear receptor co-repressor (NCoR1), resulting in repression of Rev-erbbet
164 (also known as Capicua) is a transcriptional repressor negatively regulated by RAS/MAPK signaling.
166 the chromatin binding of the transcriptional repressor neuron restrictive silencing factor (NRSF or R
167 l 1030 possible genetic circuits based on 10 repressors (NOR/NOT gates) are encoded in pools where ea
168 ggest that TDP-43 represents a translational repressor not only for specific mRNAs but for overall tr
170 ing of endogenous retroelements, as a direct repressor of a placental-specific Igf2 transcript (desig
171 we show that BldO functions as the dedicated repressor of a single key target gene, whiB, and that de
172 n-containing transcription factor Prep1 is a repressor of adipogenic differentiation since its down-r
175 rn, we demonstrate that the petunia AP2-type REPRESSOR OF B-FUNCTION (ROB) genes repress the B-functi
179 ty analysis revealed a key role for IHF as a repressor of cell motility through the control of FliA s
180 n variants of the AHK2 and AHK3 genes, named repressor of cytokinin deficiency2 (rock2) and rock3, re
181 identified miR-218 as a posttranscriptional repressor of DCC and detected coexpression of DCC and mi
182 JMJ27 is a negative modulator of WRKY25 (a repressor of defense) and a positive modulator of severa
183 XND1-RBR interaction and XND1 efficacy as a repressor of differentiation, with loss of the LXCXE mot
184 so by protecting Capicua, a transcriptional repressor of EGFR target genes, from EGFR pathway-depend
186 m gene glpR, which encodes a transcriptional repressor of factors that catalyze glycerol degradation.
187 Here, we identified Klf5 as an upstream repressor of Fgf4Fgf4 was markedly upregulated in Klf5 k
188 o GATA3 promoter in association with ZBTB32 (Repressor of GATA, ROG) and that ZBTB32 is essential for
190 Here, we demonstrate that G9a, an epigenetic repressor of gene expression, acting in the nucleus accu
193 s both an IFN-stimulated response gene and a repressor of IFN-gene transcription, suggesting the exis
195 r study establishes Grb14 as a physiological repressor of insulin mitogenic action in the liver and f
196 ch complex control is achieved because a key repressor of light signaling, the Arabidopsis (Arabidops
198 report that a newly identified bHLH factor, Repressor of MYC2 Targets 1 (RMT1), is activated by CrMY
205 -proximal binding of MAF1, a transcriptional repressor of RNAPIII activity, altogether revealing mult
207 nt activator of this exon and consequently a repressor of sIL7R, and we found strong genetic associat
210 gene of previously unknown function, to be a repressor of the cul-6/cullin gene and other IPR gene ex
211 -dependent manner that up-regulates Id2, the repressor of the receptor activator of nuclear factor-ka
212 anscription factor T-bet acts as a selective repressor of the type I interferon (IFN) transcriptional
213 longation factor S-II domain, which we named REPRESSOR OF VERNALIZATION1 (RVR1), represses VRN1 befor
217 h is induced by FGF signalling and acts as a repressor of ZRS activity, interacts with the histone de
219 dy uncovered many previously uncharacterized repressors of ERVs, and defined an essential role of Rif
221 drenoreceptors is likely one of the upstream repressors of miR-1 as treatment with beta-blockers in p
222 Cryptochromes (CRY1/2), key transcriptional repressors of this molecular apparatus, are subject to p
224 regulate localization of the transcriptional repressor Opi1p, which controls expression of phospholip
225 iptional activators (OsPCF2, OsNIN-like4) or repressors (OsCPP5, OsNIN-like2) and their encoding gene
226 e DBD-hinge helix-O-DNA module docks on core repressor, partially dehydrating phosphate oxygens and t
229 ternatively, the role ubiquitously expressed repressors play in this process is not well understood.
230 ecognized by the zinc finger transcriptional repressor Prdm1/Blimp1, an essential regulator of placen
231 riptional activators and the transcriptional repressor PRDM13 that are critical for specifying dorsal
233 bunit deadenylase complex "carbon catabolite repressor protein 4 (CCR4)-negative on TATA-less (NOT),"
234 ting expression of the developmental synapse repressor protein Ephexin5 (also known as ARHGEF15).
236 ndence of the binding of a DNA triplex and a repressor protein to distal recognition sites on superco
240 required recruitment of the transcriptional repressor repressor element-1 silencing transcription fa
242 igated the function of two broadly expressed repressors, Runt (Run) and Suppressor of Hairless [Su(H)
245 rs ZEB1, ZEB2, and the snail transcriptional repressor SNAI2, each crucial factors in mediating EMT.
246 the stability of E-cadherin transcriptional repressors, snail and slug, induced by transforming grow
249 of the Aux/IAA proteins as well as the DELLA repressors, substrate of SCF(SLY)(1) We propose that the
250 R signaling network, via loss of function of repressors such as PTEN, causes epilepsy in humans and a
251 Furthermore, redundant abaxial-enriched ARF repressors suppress WOX1 and PRS expression, also throug
252 mutation of Capicua (CIC), a transcriptional repressor, suppresses the effects of EGFR inhibition by
253 specification involving the transcriptional repressors Tbr1, Fezf2, Satb2, and Ctip2 operates in neo
255 isation of BldO, an additional developmental repressor that acts to sustain vegetative growth and pre
256 ave identified SPIN.DOC as a transcriptional repressor that binds SPIN1 and masks its ability to enga
258 Rest (also known as Nrsf), a transcriptional repressor that inhibits neuroendocrine gene expression.
259 Baf180 serve as a conserved transcriptional repressor that is critical for the maintenance of innate
260 SMAD4 interacts with SKI, a transcriptional repressor that is degraded upon TGFbeta stimulation.
262 cell lymphoma-6 (Bcl-6) is a transcriptional repressor that is required for the differentiation of T
263 o-chaperone ERdj4/DNAJB9 is a selective IRE1 repressor that promotes a complex between the luminal Hs
264 tion protein 1 (Blimp1) is a transcriptional repressor that regulates cell growth and differentiation
265 AZi functions as a flower-specific jasmonate repressor that regulates JAs, (E)-alpha-bergamotene, TPI
267 cation of a pathway-specific transcriptional repressor that silences the gene cluster under standard
268 iana) COP1/SPA ubiquitin ligase is a central repressor that suppresses light signaling in darkness by
269 ory hub for transcriptional coactivators and repressors that compete for binding and, consequently, c
270 omb group proteins (PcG) are transcriptional repressors that control cell identity and development.
271 The Aux/IAA proteins are auxin-sensitive repressors that mediate diverse physiological and develo
272 osome, long known to serve as a general gene repressor, thus also performs an important positive role
274 phosphorylation, converting Musashi2 from a repressor to an activator of target mRNA translation.
276 (PDP1epsilon) activator and the VRILLE (VRI) repressor to drive rhythmic transcription peaking at daw
277 nd antagonize the binding of FBP-interacting repressor to FUBP1, thereby coordinating the expression
278 with themselves and CRISPRi transcriptional repressors to deliver new types of RNA-based genetic cir
279 YC) activators and PERIOD-TIMELESS (PER-TIM) repressors to drive rhythmic transcription peaking at du
280 s together with self-renewal transcriptional repressors to maintain the erm immature INP enhancer in
281 suggested that the AFPs interact with the co-repressor TOPLESS to inhibit ABA-regulated gene expressi
283 is required for the interaction with the Stl repressor, usually only those Duts with normal enzymatic
284 3 and related members act as transcriptional repressors via recruitment of C-terminal Binding Protein
286 RshA anti-sigma factors and the Zur and NrdR repressors were identified as NaOCl-sensitive proteins a
287 N OF CONSTANS1-like1 (TgSOC1-like1) might be repressors, whereas TgSOC1-like2 likely is an activator,
291 miRNA-139-5p as differentially expressed RNA repressor with highest expression in the purely phasic s
293 tors (PerRs) are homodimeric transcriptional repressors with each monomer typically containing both s
294 ut indicates that overexpression of the LacI repressor would drive the system into the bistable regim
296 n zebrafish, we identify the transcriptional repressor, ZBTB11, as critical for basal and emergency g
297 , which reduces the level of transcriptional repressor ZEB1, leading to induced expression of miR-183
298 ng ERK1/2 activation and the transcriptional repressor ZEB1, leading to induction of miR-183-5p and d
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