ライフサイエンスコーパス: repressor protein

1 man gene termed SHARP (SMRT/HDAC1 Associated Repressor Protein).

2 ent before the MBT as a direct transcription repressor protein.

3 the operon was under the control of the arsR repressor protein.

4 the DNA binding activities of the phage's cI repressor protein.

5 s to the DNA binding domain of the lambda cI repressor protein.

6 into erythroid K562 cells expressing the lac repressor protein.

7 s functions as a DNA-binding transcriptional repressor protein.

8 mulated autoproteolysis of the bacteriophage repressor protein.

9 latory factor AML1 (RUNX1) to the ETO (MTG8) repressor protein.

10 oduct has significant homology with the DtxR repressor protein.

11 determines the functional state of the PpsR repressor protein.

12 h Pax2 from a transcriptional activator to a repressor protein.

13 mulus-reversible interactions with a nuclear repressor protein.

14 ral evolution of the concentration of lambda repressor protein.

15 ional and structural properties as wild-type repressor protein.

16 on by blocking the DNA-binding activity of a repressor protein.

17 ed for interaction with the TOPLESS (TPL) co-repressor protein.

18 A duplexes and a DNA duplex bound to the Lac repressor protein.

19 ctin by downregulating ZBP-89, a zinc finger repressor protein.

20 autoregulated by the copper-responsive CopY repressor protein.

21 tor binding and promoted interaction with co-repressor protein.

22 associate with Bruno, a known translational repressor protein.

23 biquitin ligase-dependent degradation of JAZ repressor proteins.

24 complex formation between the receptors and repressor proteins.

25 mmals have at least three activator and five repressor proteins.

26 ing interaction with Aux/IAA transcriptional repressor proteins.

27 ansgenes by hormone-responsive KRAB and KAP1 repressor proteins.

28 nding site for Hairy/Enhancer of split (Hes) repressor proteins.

29 n overall architecture typical for TetR/CamR repressor proteins.

30 onal activator protein and Puralpha and beta repressor proteins.

31 s; they therefore define a new family of co- repressor proteins.

32 s modulated by its interaction with specific repressor proteins.

33 ase inhibitors, suggesting involvement of co-repressor proteins.

34 tiple mechanisms involving the actions of co-repressor proteins.

35 e MexL protein belongs to the TetR family of repressor proteins.

36 atively little is known about mechanisms for repressor proteins.

37 with distinct pathway-specific, DNA-binding repressor proteins.

38 ect the differences between these homologous repressor proteins.

39 consensus CtBP-binding motif, PXDLS, in the repressor proteins.

40 euchromatic genes by Rb and perhaps other co-repressor proteins.

41 r are recruited to the template by DNA-bound repressor proteins.

42 three critical sites that bind at least two repressor proteins.

43 d that REST repression involves two distinct repressor proteins.

44 ructurally related LexA-like transcriptional repressor proteins.

45 tion depends on the regulated proteolysis of repressor proteins.

46 s sites for known eucaryotic transcriptional repressor proteins.

47 region) with those of known transcriptional repressor proteins.

48 he HNF-3/fork head, CAP and diphtheria toxin repressor proteins.

49 f jasmonate ZIM domain (JAZ) transcriptional repressor proteins.

50 elopment are controlled by the JAZ family of repressor proteins.

51 a pocket sandwiched between the HDAC and co-repressor proteins.

52 the antagonistic activities of activator and repressor proteins.

53 ystem where they function as transcriptional repressor proteins.

54 s, or other transcription co-activator or co-repressor proteins.

55 ectively for putative efflux and regulatory (repressor) proteins.

56 bunit deadenylase complex "carbon catabolite repressor protein 4 (CCR4)-negative on TATA-less (NOT),"

57 translation initiation factor eIF4E from its repressor protein 4E-BP1, which is required for vitronec

58 g Spo0A-mediated relief of repression by the repressor protein AbrB.

59 f the global transition state regulator, the repressor protein AbrB.

60 abundant member of the 4E-BP family of eIF4E repressor proteins, activates apoptosis--but only in tra

61 Chromosome tagging with GFP-Lac repressor protein allowed us to track, for the first tim

62 E-boxes but tether the mSin3 transcriptional repressor protein along with histone deacetylase thereby

63 aining mlc, which encodes a glucose-specific repressor protein, also downregulate P(sgrS)-lacZ.

64 inhibited by heterologous expression of the repressor protein AML-1/ETO.

65 inly by two elements: the concentration of a repressor protein and the dynamics of an activator prote

66 strongly with antibody prepared against the repressor protein and the protein in the R1-2 clone, but

67 -containing segments were enriched using lac repressor protein and then self-ligated.

68 x composed of the Jasmonate ZIM-domain (JAZ) repressor proteins and an E3 ubiquitin ligase complex co

69 ineered, tunable genetic switch that couples repressor proteins and an RNAi target design to effectiv

70 ound by Polycomb group (PcG) transcriptional repressor proteins and change during development, implyi

71 ng protein (CtBP) interacts with a number of repressor proteins and chromatin modifying enzymes.

72 l cis-bound antisense RNA linked to Polycomb repressor proteins and downregulated DPP10 expression.

73 e, resulting in stabilization of the Aux/IAA repressor proteins and inhibition of auxin responses.

74 lt of synergistic interactions between these repressor proteins and might involve the formation of a

75 iological role for a set of KRAB zinc-finger repressor proteins and reveals the molecular basis of a

76 een the AUXIN/INDOLE-3-ACETIC ACID (Aux/IAA) repressor proteins and the AUXIN RESPONSE FACTOR (ARF) t

77 eraction between the Aux/IAA transcriptional repressor proteins and the ubiquitin-ligase complex SCF(

78 ed stable expression of the conditional PAX3 repressor proteins and used them to down-regulate the ma

79 tem based on the interaction between the lac repressor (protein) and operator (DNA) and its interplay

80 ARP (SMRT and histone deacetylase-associated repressor protein), and class I histone deacetylases.

81 se to and subsequent degradation of the JAZ1 repressor protein, and implicate the SCF(COI1)-JAZ1 prot

82 S is a major nucleoid-structuring and global repressor protein, and RpoS is the stationary phase and

83 is tightly regulated, and P-element-encoded repressor proteins are responsible for inhibiting transp

84 Its integrase and repressor proteins are similar to those of lambda, but t

85 en fused to the amino-terminal portion of cI repressor protein, as shown by immunity of Escherichia c

86 e histone acetylation, or 2) the action of a repressor protein at cis-elements located outside of the

87 oligomerization of the bacteriophage lambda repressor protein at micromolar concentrations.

88 Furthermore, the Hes1 repressor protein augmented Smad3 transactivation of the

89 Hey1 of the hairy/Enhancer of split-related repressor protein basic helix-loop-helix family was amon

90 The transcriptional repressor protein BCL-6, implicated in the pathogenesis

91 The transcriptional repressor protein BCL6 regulates T cell differentiation

92 mechanisms, including the recruitment of co-repressor proteins belonging to the TLE family of chroma

93 istent with a decline in single-stranded DNA repressor protein binding.

94 s to CpG island methylation, causing loss of repressor protein binding.

95 oter, which is recognized by the pIJ101 KorB repressor protein; binding of KorB appears to prevent th

96 Lac repressor protein binds simultaneously to two operator s

97 The yeast Rox1 hypoxic transcriptional repressor protein binds to and bends a specific DNA sequ

98 time to induce expression of the zinc finger repressor protein Blimp1 (B-lymphocyte-induced maturatio

99 Here we show that the polycomb repressor protein Bmi1 marks a population of castration-

100 alysis of binding affinity data from the Mnt repressor protein bound to all possible DNA (sub)targets

101 Here, we used repressor proteins bound to operator arrays to generate

102 was found to enhance the effects of the erp repressor protein, BpaB.

103 nteraction between Sqd and the translational repressor protein Bruno.

104 s requires recruitment of transcriptional co-repressor proteins by Pbx1a.

105 he rotational settings imposed on DNA by the repressor proteins, by contrast, introduce sequential sp

106 on factor eIF4E-binding protein) translation repressor protein Caf20, and the Golgi-associated adapto

107 al regulatory role is played by an activator-repressor protein (called C, for controller).

108 results demonstrate that SID-containing KLF repressor proteins can inhibit cell growth and neoplasti

109 These results identify Dnmt3a as a co-repressor protein carrying deacetylase activity and show

110 utations that predict a truncated functional repressor protein cause PHS and that functional haploins

111 Here we identify a novel co-repressor protein, CBFA2T2, that regulates pluripotency

112 he mediator of these processes is the lambda repressor protein, CI, and its interactions with lambda

113 tained by a highly regulated level of lambda repressor protein, CI, which represses lytic functions.

114 he cleavage of full-length Ci to a truncated repressor protein, Ci75, in a process that is dependent

115 The transposase and repressor proteins compete for the operator/IAS region u

116 AdcR is a metal-dependent repressor protein containing a putative metal-binding si

117 However, 933W repressor protein contains neither an Ala-Gly nor an alt

118 their ability to interact with activator and repressor proteins, control expression of genes involved

119 vator protein, XLNR, and a carbon catabolite repressor protein, CREA.

120 A copper-sensitive operon repressor protein (CsoR) has been identified in Streptom

121 at YY1, as well as Polycomb, required the co-repressor protein CtBP for repression in vivo.

122 es p300, CBP and P/CAF, and also with the co-repressor protein CtBP.

123 ctions between the Escherichia coli cytidine repressor protein (CytR) and its operator sites at the d

124 d HDAC1 interaction with the transcriptional repressor protein DAXX.

125 e amino-terminal DNA-binding domain from the repressor protein determined by heteronuclear multidimen

126 log of the mammalian Mad/Mnt transcriptional repressor proteins (dMnt), which is thought to antagoniz

127 cause when translocation is blocked by a Lac repressor protein, DNA cleavage is similarly blocked.

128 tory mechanism in which the diphtheria toxin repressor protein (DtxR) and iron repress expression whi

129 gulates the activity of the diphtheria toxin repressor protein (DtxR) requires information about the

130 d COR and co-operation between JAZ jasmonate repressor proteins during DC3000 infection.

131 Here, we report that the transcriptional repressor protein Earmuff (Erm) functions temporally aft

132 endent balanced recruitment of activator and repressor proteins enables differential transcriptional

133 ting expression of the developmental synapse repressor protein Ephexin5 (also known as ARHGEF15).

134 These include translational repressor proteins (eukaryotic initiation factor 4E-bind

135 n profoundly altered affinity of the lactose repressor protein for its wild-type target sequence.

136 The fates of BlaI, the gene repressor protein for the bla operon, BlaR1, the beta-la

137 n regulates root growth by targeting Aux/IAA repressor proteins for degradation.

138 fused to the DNA binding domain of lambda cI repressor protein formed dimers, as shown by immunity of

139 tes with RP58, a DNA-binding transcriptional repressor protein found at transcriptionally silent hete

140 ted on four single-tryptophan mutants of lac repressor protein from Escherichia coli: H74W/Wless, W20

141 extrachromosomally encoded metalloregulatory repressor protein from the ArsR superfamily which negati

142 TetR repressor proteins from the Agrobacterium tet system and

143 due to the stochastic dissociation of Her1/7 repressor proteins from the oscillating her1/7 autorepre

144 ed regulation of these promoters through the repressor protein Fur is a consequence of the relative p

145 hat environmental iron and the ferric uptake repressor protein (Fur) play in the regulation of the ig

146 lf negatively regulated by the ferric uptake repressor protein, Fur (Ferric uptake regulator).

147 O operator sites visualized by LacI and TetR repressor proteins fused with GFP (green fluorescent pro

148 signals the degradation of the DELLA growth repressor proteins GAI and RGA, promoting root cell prod

149 It involves binding of two dimeric Gal repressor proteins (GalR) to two operators, O(E) and O(I

150 Mice lacking the zinc finger transcriptional repressor protein GFI-1 are neutropenic.

151 s report, we show that recruitment of the co-repressor protein Grg4 to a Pax DNA-binding site displac

152 proteins is the site of interaction with the repressor protein Groucho.

153 raction of Su(H) does not associate with the repressor proteins Groucho and CtBP.

154 By contrast, the co-repressor proteins Groucho and dCtBP, and the histone de

155 the molecular mechanism of recruitment to co-repressor proteins has yet to be established.

156 ber of the BTB/POZ family of transcriptional repressor proteins, has been shown to bind to FANCC, the

157 By contrast, numerous CSL co-repressor proteins have been identified, and these are m

158 regulated by a constitutive transcriptional repressor protein, heterogeneous nuclear ribonucleoprote

159 E2-induced decrease in levels of the memory repressor protein histone deacetylase 2.

160 regulated by a constitutive transcriptional repressor protein, hnRNP A1, and the decreased binding a

161 ESS functions as a binding site for a known repressor protein, hnRNP A1, which binds to SMN2 but not

162 ble) genes and cleavage of the UmuD and LexA repressor proteins; however, recX inactivation had no ef

163 r transcription is regulated by a heat-shock repressor protein HrcA.

164 sion and transfer by inactivating the ICEBs1 repressor protein ImmR.

165 bacteriophage 186 is governed by the 186 CI repressor protein in a unique way.

166 y regulated by the BirA protein, an atypical repressor protein in that it is also an enzyme.

167 structure and expresses functional levels of repressor protein in the animal.

168 lecular Cell, Hu et al. identified JAV1 as a repressor protein in the JA pathway that enables the pla

169 cAMP-dependent protein kinase that acts as a repressor protein in the Shh pathway, and four subjects

170 interact separately or together with TLX, a repressor protein in the tailless transcription factor f

171 The relocalization of repressor proteins in HD brain may alter transcription a

172 on of auxin (aux)/indole-3-acetic acid (IAA) repressor proteins in the presence of auxin.

173 or independence 1 (Gfi-1), a transcriptional repressor protein, in the H369W DNA element.

174 to be through the formation of a complex of repressor proteins including the N-CoR, mSin3 and histon

175 Furthermore, epithelial NF-kappaB super repressor protein inhibited diarrhea and blocked changes

176 Stat5, resulting in the removal of the Stat-repressor protein inhibitor of activated Stat 3 (PIAS3),

177 ments, we have determined that Sfl1, a novel repressor protein, interacts directly with Ssn6, and in

178 ain (residues 192-315) is similar to MarR, a repressor protein involved in bacterial antibiotic resis

179 This is the first report of a specific repressor protein involved in the transcriptional contro

180 om triggering inappropriate transcription by repressor proteins Irx3 and Nkx2.2.

181 The DNA-binding domain of the KP repressor protein is also shared with the transposase pr

182 he B cell lymphoma-6 (BCL-6) transcriptional repressor protein is an important regulator of B cell di

183 The B cell lymphoma (BCL)-6 transcriptional repressor protein is an important regulator of Th2 respo

184 Inactivation of the lambdoid phage repressor protein is necessary to induce lytic growth of

185 how that ZBP-89, a zinc finger, Kruppel-like repressor protein is vimentin's silencer element binding

186 Dimerization of this small repressor protein is weak, however, and proline residues

187 ativity between KorB and either KorA or TrbA repressor proteins is a key element of these circuits an

188 ate that xKaiso, a novel methyl-CpG specific repressor protein, is required to maintain transcription

189 omologous to the Escherichia coli catabolite repressor protein, is thought to be the major cAMP-bindi

190 targets JASMONATE ZIM-domain transcriptional repressor proteins (JAZs) for proteasome-mediated degrad

191 n factor Nrf2 (also known as Nfe2l2) and its repressor protein Keap1.

192 cale simulation of a complex between the lac repressor protein (LacI) and a 107-bp-long DNA segment i

193 harged K84 side chains of tetrameric lactose repressor protein (LacI) are found buried within the hig

194 The lac repressor protein (LacI) efficiently represses transcrip

195 The Escherichia coli lactose repressor protein (LacI) provides a classic model for un

196 the binding of constitutively expressed Lac repressor protein (LacI) to operator sequences within th

197 Lactose repressor protein (LacI) utilizes an allosteric mechanis

198 between unliganded and inducer-bound lactose repressor protein (LacI), which were previously presumed

199 a bacterial transcription regulator, lactose repressor protein (LacI).

200 that constitutively express the E. coli Lac repressor protein (LacI).

201 links two functional domains within lactose repressor protein (LacI).

202 DNA sequences to a series of mutant lactose repressor proteins (LacI).

203 addition, we found that the transcriptional repressor protein, lethal (3) malignant brain tumor prot

204 One repressor protein, LRRFIP1, bound directly to the noncod

205 ster have a single E2F activator protein and repressor protein, mammals have at least three activator

206 he general transcriptional machinery and the repressor protein MDM2, and p65, which is reported to bi

207 ns in a gene encoding the methyl-CpG-binding repressor protein MECP2 provided a significant breakthro

208 This process recruits various transcription repressor proteins [methyl-CpG binding protein (MeCP2) a

209 these proteins is governed by the methionine repressor protein MetJ and its co-repressor, the methion

210 o characterize the binding of the methionine repressor protein, MetJ, to synthetic oligonucleotides c

211 For example, two repressor proteins might control one another's synthesis

212 MMB, which contains both known activator and repressor proteins, might function as part of a switchin

213 e created a monomeric variant of the lactose repressor protein (MLAc), a well characterized tetrameri

214 a phosphorelay pathway, while an additional repressor protein modulates this interaction.

215 chitin, resulting in elevated levels of the repressor protein, NodD2.

216 nce that NMNAT1 interacts with the nucleolar repressor protein nucleomethylin and is involved in regu

217 The repressor protein of bacteriophage Mu establishes and ma

218 mperature-sensitive mutant of the tryptophan repressor protein of Escherichia coli in which surface-e

219 brane protein that binds the transcriptional repressor protein Opi1p.

220 tion occurs via the repression of additional repressor proteins, or small regulatory RNAs, thereby ac

221 The P22 c2 repressor protein (P22R) binds to DNA sequence-specifica

222 Transcriptional repressor proteins play essential roles in controlling t

223 Transcriptional repressor proteins play key roles in the control of gene

224 The refolded repressor protein possessed the same functional and stru

225 ess, the physical mechanism by which the Lac repressor protein prevents transcription of the lactose

226 e to the binding of the interferon-inducible repressor protein promyelocytic leukemia protein (PML) a

227 ac operator sequence, which binds to the lac repressor protein, providing a simple and rapid way to p

228 d in vitro and that it directly binds to the repressor protein RcoLS20 in a 1:1 stoichiometry.

229 studies of the phage RB69 RegA translational repressor protein, regA was configured to add six histid

230 ory (HIR) and histone promoter control (HPC) repressor proteins regulate three of the four histone ge

231 Lactose repressor protein, regulator of lac enzyme expression in

232 epression in nonneural cells mediated by the repressor protein REST/NRSF (RE1 silencing transcription

233 or by altering the interaction of PAX2 with repressor proteins, resulting in enhanced repressor acti

234 signal-regulated kinase and transcriptional repressor protein retinoblastoma, and increased expressi

235 ss the GA signaling pathway by degrading the repressor protein RGA.

236 ess the GA response pathway by degrading the repressor protein RGA.

237 the loss of either one of the downstream co-repressor proteins Rgt1p or Mth1p.

238 MAP kinase Fus3 phosphorylates two specific repressor proteins Rst1 and Rst2 (also known as Dig1 and

239 In this study, the possible involvement of repressor protein(s) in suppressing MDR1 promoter activi

240 sed upon COI1-dependent turnover of a labile repressor protein(s).

241 d receptors/histone deacetylase 1-associated repressor protein (SHARP) protein potently enhanced beta

242 Here, we demonstrate that the co-repressor protein Sin3a is crucial for lung endoderm dev

243 yqxM-sipW-tasA operons are controlled by the repressor proteins SinR and AbrB.

244 obin, we postulated that the transcriptional repressor protein SLUG increases the motility of the agg

245 ignaling and the Zinc finger transcriptional repressor protein Slug, in vimentin-deficient (VIM(-/-))

246 We explored whether the E2-box-binding repressor protein SLUG, which is of similar molecular si

247 oth NPM-RAR and PML-RAR interact with the co-repressor protein SMRTe in a manner that is less sensiti

248 has been purified in complexes that contain repressor proteins such as CtBP2, suggesting that it act

249 in (the TRD) of MBD1, which recruits several repressor proteins such as MCAF1, HDAC3 and MPG that are

250 eceptors is mediated by interactions with co-repressor proteins such as SMRT and N-CoR, which in turn

251 d selectively inhibited by the presence of a repressor protein targeted to the MDR1 promoter.

252 The oncogenic transcriptional repressor protein TBX2 interacted with NRAGE, repressing

253 ther with the scaffold protein eIF4G or with repressor proteins termed eIF4E-binding proteins (4E-BPs

254 By genetically encoding Tet Repressor protein (TetR)-binding RNA elements into the 5

255 ism involving the release of a translational repressor protein that allows the immediate initiation o

256 eterochromatin and associates with Ikaros, a repressor protein that also colocalizes with centromeric

257 assays indicate that ZntR is a trans-acting repressor protein that binds to the znt promoter region

258 the Ars operon that is regulated by ArsR, a repressor protein that dissociates from DNA when As(III)

259 Sum1p is a local repressor protein that mediates repression of meiosis-sp

260 ovides in vivo evidence that Dd-STATa is the repressor protein that regulates commitment to stalk cel

261 rric uptake regulator (Fur), an iron-sensing repressor protein that typically regulates expression of

262 constitutive expression was due to loss of a repressor protein that was encoded by one of the other g

263 lation can be achieved through activator and repressor proteins that bind to DNA and switch particula

264 ation is generally attributable to activator/repressor proteins that bind to specific DNA sequences.

265 We further show that Nrg1 and Nrg2, two repressor proteins that interact with Snf1, function as

266 ated prior to depletion, indicating that the repressor proteins that recruit Tup1 function as activat

267 the activity of short-range transcriptional repressors, proteins that play key roles in development.

268 s the expression of Par-4, a transcriptional repressor protein, that is essential but not sufficient

269 In the inducer-bound structure of the lac repressor protein, the side chains of H74 and D278 are p

270 caffold protein, eIF4G and the translational repressor proteins, the eIF4E-binding proteins (4E-BPs),

271 Acid (Aux/IAA, referred to hereafter as IAA) repressor proteins through interaction with auxin recept

272 s, demonstrated binding of the translational repressor protein TIA-1 to COX-2 mRNA.

273 d1-like SID is also present in five Sp1-like repressor proteins (TIEG1, TIEG2, BTEB1, BTEB3 and BTEB4

274 Thus, CPEB appears to act as a translational repressor protein to control myc translation and resulti

275 ndence of the binding of a DNA triplex and a repressor protein to distal recognition sites on superco

276 ein 1 (4E-BP1) and increased binding of this repressor protein to eIF4E.

277 iated looping prevents overexpression of the repressor protein to preserve sensitivity to conditions

278 ereby monomethylated H4K20 binds the L3MBTL1 repressor protein to repress specific genes, including R

279 erential binding of a putative transcription repressor protein to the C allelic promoter.

280 ome insight into the mechanisms used by some repressor proteins to diffuse and bind to specific DNA-b

281 e of mimicking the function of transcription repressor proteins to downregulate gene expression at th

282 sts that both animals and plants use similar repressor proteins to regulate critical developmental pr

283 inished expression of TNF and recruitment of repressor proteins to the locus.

284 The bacterial repressor protein, trp repressor, is one of the best stu

285 nsitive mutant (L75F-TrpR) of the tryptophan repressor protein (TrpR) of Escherichia coli in its apo

286 ctures in the presence and absence of the co-repressor protein Tup1.

287 Upon finding a binding site, the repressor protein undergoes an additional conformational

288 less effectively induced, and the AXR3 auxin repressor protein was less effectively eliminated in suc

289 t full-length metal permease-transcriptional repressor protein was processed during the course of inf

290 e Spen protein, SHARP (SMRT/HDAC1-associated repressor protein), was identified as a component of tra

291 To identify a repressor protein, we used a mass spectroscopy-based RNA

292 activities of endogenous or chimeric Knirps repressor proteins were assayed on integrated reporter g

293 hR), trehalose (TreR), and l-arginine (ArgR) repressor proteins were functionalized to detect pyruvat

294 coli -expressed C-terminal human and rat co-repressor protein which pulled full-length huntingtin ou

295 of a single fluctuating extrinsic variable-a repressor protein, which acts on the gene of interest.

296 omoter is controlled by a pheromone receptor/repressor protein whose activity is determined by its in

297 A-isoleucine triggers the interaction of JAZ repressor proteins with the F-box protein CORONATINE INS

298 dynamics of the Escherichia coli tryptophan repressor protein (WT-TrpR) and two functionally distinc

299 The homeodomain repressor protein Yox1p acts in a complex with Mcm1p to

300 pression by targeting engineered zinc finger repressor proteins (ZFPs) to the gamma2-specific promote