ライフサイエンスコーパス: reproducibly

1 PrepT-stage and prepN-stage can be estimated reproducibly.

2 quantities of RNA robustly, efficiently and reproducibly.

3 rotein-carbohydrate interaction of interest, reproducibly.

4 nd thus how to generate L-forms reliably and reproducibly.

5 omes of around 50,000 nodes can be generated reproducibly.

6 kness of approximately 10 nm that was formed reproducibly.

7 Da, 10(-14) m) are detected selectively and reproducibly.

8 tivities of 326 +/- 20 MBq/nmol are obtained reproducibly.

9 of peripheral proteins very efficiently and reproducibly.

10 -quality aptamers rapidly, economically, and reproducibly.

11 ration for complex systems automatically and reproducibly.

12 PrepT-stage and prepN-stage can be estimated reproducibly.

13 pes, however, are often difficult to measure reproducibly.

14 when patterns of morphogen molecules emerge reproducibly [4, 5].

15 g the molecule in a gated junction, we found reproducibly a Kondo effect (zero-bias conductance) attr

16 Our diagnostic model was reproducibly accurate in both the internal (0.95, 0.91-0

17 With this method, we reliably and reproducibly achieve rectification ratios in excess of 2

18 static incubation, the incubation period is reproducibly achieved by varying the number of forward a

19 we report that bioluminescent imaging can be reproducibly achieved with primary human ALL samples.

20 of fractional injections (0.003%-56%) can be reproducibly achieved, providing a means for minute volu

21 We developed an approach that reproducibly achieves near-complete elimination of 5-HT

22 e, we have developed a genetic approach that reproducibly achieves near-complete elimination of 5-HT

23 It was found that AV6 reproducibly activated latent provirus from different ly

24 CH2CH2NSiiPr3)3] with 0.25 equivalents of P4 reproducibly affords the unprecedented actinide inverted

25 These patterns, and thus functions, change reproducibly after mating.

26 Here, we show that SCS reproducibly alleviates motor deficits in a primate mode

27 , consumption of a high-fat, high-sugar diet reproducibly altered the gut microbiota despite differen

28 anges in T cells, which are dramatically and reproducibly altered with aging.

29 e biomarkers because they vary naturally and reproducibly among foods, and those variations are captu

30 of an HPLC system, we can quantitatively and reproducibly analyze mixtures of purine bases, with limi

31 Dilution is achieved online, reproducibly and in seconds by diffusion/mixing that occ

32 environments, and they were found to behave reproducibly and possess a lifetime of up to 6 weeks.

33 reaction monitoring (SRM)-based strategy to reproducibly and quantitatively monitor the abundances o

34 LC-MS(E)) method to measure bile acids (BAs) reproducibly and reliably in biological fluids and have

35 We show that the stripe-superlattices can be reproducibly and reversibly manipulated with submicromet

36 um gene expression signature of 6 biomarkers reproducibly and significantly discriminates inflammator

37 All mats released H2 reproducibly and sustainably for 1.5 years.

38 cted autoantibodies to hLAMP-2 in human sera reproducibly and with comparable sensitivity and the ass

39 In vivo, fursultiamine did not reproducibly antagonize the effect of hepcidin on serum

40 r for perovskite solar cells to reliably and reproducibly approach their thermodynamic efficiency lim

41 andidate regions revealed that most function reproducibly as enhancers active in the heart, irrespect

42 ment of an intuitive platform to rapidly and reproducibly assay IPL lamination.

43 es guidance to how other icosahedral viruses reproducibly assemble into capsids with a predetermined

44 inge-based assay systems that can be used to reproducibly assess induced innate or adaptive immune re

45 WAS) have identified several novel loci that reproducibly associate with coronary artery disease (CAD

46 Genome-wide association studies (GWAS) have reproducibly associated variants within introns of FTO w

47 We identified 134 SNPs that were reproducibly associated with ALL relapse.

48 netic studies have identified numerous genes reproducibly associated with asthma, yet these studies h

49 hirteen common susceptibility loci have been reproducibly associated with cutaneous malignant melanom

50 ndividual protein-altering variants that are reproducibly associated with extremely high intelligence

51 rnal factors and in observational studies is reproducibly associated with future risk of adult metabo

52 main containing 3 (rs738409, I148M) has been reproducibly associated with increased hepatic triglycer

53 No single variant in A2BP1 was reproducibly associated with obesity across the differen

54 ants which are among those most strongly and reproducibly associated with obesity.

55 Accordingly, TP53 mutations are reproducibly associated with poor treatment outcomes.

56 Most pores healed reproducibly at temperatures above the glass-transition

57 ified five M. tuberculosis mutants that were reproducibly attenuated for biofilm production relative

58 ed that simple hemodynamic manipulations can reproducibly augment intimal hyperplasia and remodeling

59 Proteins most reproducibly binding CRBN (>fourfold vs controls) includ

60 For each protein that reproducibly bound measurable quantities of bulk RNA (90

61 ocity and established regression models that reproducibly capture the signatures of these relationshi

62 wn that a specific region of the nucleoid is reproducibly captured in the forespore, the mechanism un

63 In contrast, whole-genome sequencing reproducibly cataloged genomic variants (131,424 differe

64 cy in AGS cells identified a large number of reproducibly changed genes.

65 ew methods that can quickly, accurately, and reproducibly characterize the three-dimensional structur

66 nsistent image feature annotation capable of reproducibly characterizing brain tumors; this study sho

67 s, it is unclear how specific rRNA genes are reproducibly chosen for silencing.

68 -sized solid electrodes whose surface can be reproducibly cleaned by mechanical polishing, cleaning t

69 of these complexes allows us to reliably and reproducibly collect continuous visual information about

70 Animal epithelial tissue becomes reproducibly colonized by specific environmental bacteri

71 , we describe diblock star polymers that can reproducibly complex double-stranded oligonucleotides in

72 LE proteins and riboswitches, to rapidly and reproducibly control the expression of downstream target

73 monolayers, the lipid packing density can be reproducibly controlled and changed as desired.

74 antum fluids, since they can be manufactured reproducibly, cover the frequency range from hundreds of

75 We describe how sequencing libraries can be reproducibly created from 20 pg of input DNA using a mod

76 surface that is pinned by wire loops can be reproducibly cut without formation of satellite droplets

77 e TLR7 receptor agonist imiquimod subtly yet reproducibly decreases time to skin graft rejection elic

78 480 bioactive compounds, identifying 11 that reproducibly delay fragmentation of severed axons in vit

79 ate drug release for at least 3 h, and could reproducibly deliver short pulses over at least 10 cycle

80 Mutants that were reproducibly depleted following squid colonization repre

81 tension (PO2) for more than 2 weeks and can reproducibly detect acute changes in cortical oxygenatio

82 The TRAP assay can only reproducibly detect approximately 2-fold differences and

83 rioritization correlates with the ability to reproducibly detect interactions among replicates.

84 We were able to reproducibly detect magnetic cells and to determine thei

85 during library preparation and sequencing to reproducibly detect mutations down to a frequency of 2.4

86 ility between measurements and enables us to reproducibly detect small differences in cell mechanics.

87 results indicate that current assays do not reproducibly detect XMRV/MLV in blood samples and that b

88 The method reproducibly detected acute changes in cortical oxygenat

89 All type-specific qPCR assays reproducibly detected as few as 10 copies/reaction of qu

90 These lncNATs could be reproducibly detected by different technical platforms,

91 ked Au-MNPs, bacteria can be sensitively and reproducibly detected directly using SERS.

92 MEAs reproducibly detected glutamate on a second-by-second ti

93 C terminus of the mature capsid protein and reproducibly detected low levels of the viral nonstructu

94 , although a small contribution from En2 was reproducibly detected.

95 at least one occasion, with 83% of protocols reproducibly detecting this concentration.

96 highly sensitive to viability phenotypes and reproducibly detects SS/L interactions.

97 athway in live human melanoma samples can be reproducibly determined using a novel automated platform

98 Rodent models reproducibly develop mild or severe disease.

99 ions of the EGFR-mutant PC9 cell line, which reproducibly develops EGFR T790M as a mechanism of drug

100 ary, we describe a KrasG12D mouse model that reproducibly develops JMML-like disease.

101 ereomers betamethasone and dexamethasone are reproducibly different.

102 th of pools of previously cloned mutants and reproducibly differentiated between deleterious and neut

103 A 64-gene profile reproducibly differentiated severe NAFLD from mild NAFLD

104 In response to BMP4, colonies reproducibly differentiated to an outer trophectoderm-li

105 estigated for its ability to efficiently and reproducibly digest specific classes of gluten in barley

106 ic stem cells (hESCs) can be efficiently and reproducibly directed into cardiomyocytes (CMs) using st

107 -stir superstructure ( approximately 100 nm) reproducibly disintegrated pecan shell biochar pellets (

108 Ca(2+)-ATPase (SERCA) Ca(2+) pump inhibitor, reproducibly displayed significantly more activity in th

109 situations around ceramic implants could be reproducibly distinguished.

110 regulators of cholesterol biosynthesis were reproducibly down-regulated in Tet1/3 DKO blastocysts, r

111 esults demonstrate that molecular motors can reproducibly drive proteins through a model nanopore--a

112 Given that only a fraction of sites are reproducibly edited in multiple cell lines and that we f

113 ain to make ACT with gene-modified T cells a reproducibly effective and safe therapy and to expand th

114 Reproducibly elevated IgG binding was elicited by 208 "a

115 goal of HIV research is to develop vaccines reproducibly eliciting broadly neutralizing Abs (bNAbs);

116 ere the observed extent of peripheral damage reproducibly engenders the same level of pain across ind

117 To reproducibly engineer the low energy amphiphile self-ass

118 The Raman scatter was reproducibly enhanced at the interface containing a gold

119 opulations with distinct properties that are reproducibly enriched under conditions that characterize

120 Sixty-nine Ser-rich proteins were reproducibly enriched with AAL, including nucleoporins,

121 mics raise questions regarding how cells can reproducibly establish patterns of gene expression from

122 However, the mechanisms that reproducibly establish these patterns during each round

123 The device reproducibly establishes a nearly linear pH gradient fro

124 he overall [(12)C-LCFA]Tot/[HSA]Tot ratio is reproducibly estimated in a manner that is only minimall

125 This SGS genotyping method efficiently and reproducibly estimates parasite allele frequencies withi

126 s of the CD8 T-cell response and whether HBV reproducibly evades CD8 T-cell immune pressure by mutati

127 , but quantitative biomarkers to rapidly and reproducibly evaluate heterogeneity in a clinical settin

128 pathologies in AMD can be qualitatively and reproducibly evaluated with SD-OCT, identifying patholog

129 e width, where a null heart rate response is reproducibly evoked during the on-phase of VNS.

130 the product of each digestion (1631.8 + 199) reproducibly exceeds that obtained using the standard BM

131 One promising way to reproducibly expand T cells for cancer therapy is by att

132 rate induced strain changes we show a way to reproducibly explore the effects of temperature and stra

133 We have tested whether DDF can reproducibly extract and fractionate cellular protein co

134 lectrodes with a radius less than 10 nm were reproducibly fabricated using an optimized laser pulling

135 the surface between measurements, and can be reproducibly fabricated using the proposed approach.

136 these techniques as "PectI" dramatically and reproducibly focused the bacteria to a single peak with

137 d that we can sensitively, specifically, and reproducibly follow enzyme-mediated nucleosome acetylati

138 vesicles tether to the plasma membrane very reproducibly for approximately 18 s, which is extended i

139 Chimeras were found to reproducibly form among independent amplifications and c

140 Here, we used dialysis to reproducibly form planar and vesicular BCP membranes wit

141 This E1-->E2-->E3 erythroid series reproducibly formed ex vivo, enabling further characteri

142 ed the regulated attachment method (RAM) for reproducibly forming lipid bilayers within flexible subs

143 ineage (Asteraceae), where HSS expression is reproducibly found in specific cells of the endodermis a

144 Hit clusters were reproducibly found over known binding sites on small nuc

145 nlinked to malignant breast cancer that were reproducibly found to be induced in several models of tu

146 velopmental events, bioengineered constructs reproducibly generate desired tissue architectures.

147 Here, we combine these two approaches to reproducibly generate human forebrain tissue while maint

148 of ion while removing another type of ion to reproducibly generate pH/concentration gradients.

149 ering of ovarian cancers using the 378 genes reproducibly generated a distinct gene cluster strongly

150 Transformed lines are reproducibly generated and selected within 14-20 d, and

151 The method reproducibly generated the same consensus sequence, cons

152 High-spin 7 is also reproducibly generated via the addition of H2O to {[Fe(I

153 pite this variability, embryonic development reproducibly generates form and function.

154 Reading center teams reproducibly graded IRF (percent agreement = 73%, kappa

155 Among those 68 isolates, 45 were reproducibly GRD positive.

156 oupling between two 40 nm gold nanoparticles reproducibly held with gaps of 3.3 +/- 1 nm.

157 [(18)F]5 was synthesized in reproducibly high radiochemical yields and purity (>98%)

158 However, specific fractions showed reproducibly higher cytotoxicity than other fractions as

159 visually definable phenotypes, our framework reproducibly identified 10 Golgi phenotypes.

160 ng of 94 protein antigens, ten of which were reproducibly identified across four contemporary invasiv

161 ause the IL33 and ST2/IL1RL1 genes have been reproducibly identified as major susceptibility loci in

162 g these putative motifs, the FCBS dataset of reproducibly identified FMRP binding sites is a valuable

163 The 1-CSRT task reliably and reproducibly identified high impulsive (HI) and low impu

164 ically, these developmental differences were reproducibly identified in a second independent cohort o

165 elanoma, germline CDKN2A mutations have been reproducibly identified in melanoma-prone kindreds world

166 nsensus binding sequences (FCBS), which were reproducibly identified in two published FMRP CLIP seque

167 etic markers of treatment response have been reproducibly identified.

168 QUAliFiER tool objectively, efficiently, and reproducibly identifies outlier samples in an automated

169 existing 4C-Seq pipelines in its ability to reproducibly identify interaction domains at all genomic

170 a model for complex mammalian proteomes, we reproducibly identify over 4000 proteins across duplicat

171 ith viral escape, the selected substitutions reproducibly impaired recognition by HBV-specific CD8 T

172 havioral assays can be performed rapidly and reproducibly in 96-well, high-throughput format.

173 Crystals are self-assembled reproducibly in confined spaces of 100 nm diameter with

174 Inhaled capsaicin elicits cough reproducibly in human subjects and is widely used in the

175 bel-free adenine molecules could be detected reproducibly in real time.

176 egion of the central nervous system, but not reproducibly in the adult ENS.

177 SARS)-like pathology observed with MHV-1 and reproducibly increased pneumovirulence relative to rA59/

178 Genome-wide association studies reproducibly indicate an association of SZ with immune g

179 A distinct HOXB4 transcriptional program was reproducibly induced and stabilized by 12 weeks after tr

180 Furthermore, hTR knockdown reproducibly induced apoptosis in the absence of any det

181 A single premature beat reproducibly induced self-terminating AF in 10 of 17 atr

182 Our Tf reagent reproducibly induces coagulation, making it an ideal too

183 Twenty animals with reproducibly inducible sustained monomorphic ventricular

184 criptional regulation as a versatile tool to reproducibly interrogate tumor phenotypes in vivo.

185 rofluidic channel is used to efficiently and reproducibly introduce sample containing soluble protein

186 hCDCs can be reproducibly isolated and expanded from young human myoc

187 50)} as the major product, allowing it to be reproducibly isolated in a moderate yield, as opposed to

188 These findings will be useful for reproducibly isolating DOM with representative molecular

189 ing 200 or more nucleotides of a target gene reproducibly knock down target gene expression by approx

190 the 17,000 GFP-positive CST axons that were reproducibly labeled in brainstem from the spinal cord.

191 body and chemical capture generated profiles reproducibly link to unique chromatin modification profi

192 er, linkage studies have identified very few reproducibly linked loci in diseases such as diabetes an

193 ith this development, SPME fibers can now be reproducibly loaded with derivatization reagent, from an

194 Higher circuit-density reproducibly localized to regions of shorter wavelength.

195 Four molecules have shown reproducibly low micromolar inhibition of calpain-2.

196 ed the population of 5HT neurons that can be reproducibly manipulated to identify those that modulate

197 nut and celeriac ingredients and that can be reproducibly manufactured has been developed.

198 The ability to reliably and reproducibly measure any protein of the human proteome i

199 ible method to non-subjectively, rapidly and reproducibly measure both size and stability of the inte

200 thylsiloxane microfluidics platform that can reproducibly measure kinase activity from as few as 3,00

201 fered from a paucity of in vitro assays that reproducibly measure the anti-parasitic activity induced

202 ing require phosphoproteomic techniques that reproducibly measure the same phosphopeptides across mul

203 rt because it is difficult to accurately and reproducibly measure the size of HIV reservoir in this s

204 more frequently than CIN2+, and can be more reproducibly measured as a primary endpoint.

205 We reproducibly measured current-voltage characteristics of

206 ere small and difficult to observe, but were reproducibly measured for residues over a wide area of t

207 The SD-OCT is capable of reproducibly measuring choroidal thickness in the peripa

208 en created by which glycan expression can be reproducibly monitored.

209 y modified with CD8-LV killed melanoma cells reproducibly more efficiently than CD8(+) cells transduc

210 Shorter renal allograft survival is reproducibly observed after DDKT from APOL1 2-renal-risk

211 ns, including dendritic cell loss, have been reproducibly observed in patients with septic shock and

212 ercial Pt/C (2.7 A mgPt(-1) at 0.9 VRHE) was reproducibly observed upon annealing at 300 degrees C.

213 activity of 55.5 MBq/nmol (0.37 MBq/mug) was reproducibly obtained with [(89)Zr]Zr-daratumumab-DFO.

214 fectly coregistered MRI and PET volumes were reproducibly obtained.

215 The ability to reproducibly pattern silk biopolymers with arbitrarily c

216 Here, I present five reasons why working reproducibly pays off in the long run and is in the self

217 We find that these angiogenic sprouts reproducibly penetrate into the hindbrain via the rhombo

218 Coated microneedles were able to reproducibly perforate human skin at low (<1N) insertion

219 s stably produced over 7 d, and results were reproducibly performed over several freeze-thaw cycles.

220 e positions, whereas a small fraction showed reproducibly positioned nucleosomes.

221 2% for initial screen positive and 24.4% for reproducibly positive results.

222 e marks examined, increased H3K9 methylation reproducibly preceded a rise in DNA methylation as cells

223 here are no biomarkers that consistently and reproducibly predict for lack of benefit in wild-type pa

224 as the first step in developing methods for reproducibly predicting ARMD phenotype conversion.

225 SPIEC-EASI also reproducibly predicts previously unknown microbial assoc

226 ic silica columns have been successfully and reproducibly prepared and characterized with comparisons

227 urtzite or mixed lattice structures could be reproducibly prepared to decay radiatively in unity quan

228 solvent (the "ink") can be controllably and reproducibly printed onto electrospun nanofiber meshes (

229 cation of elastase to murine thoracic aortas reproducibly produced aneurysms with molecular and histo

230 n efficiency at 10,000 psi was increased and reproducibly produced more peptic peptides versus digest

231 mine the minimum feature sizes that could be reproducibly produced using 3D printing fabrication.

232 emand" (DOD) aerosol generator is capable of reproducibly producing very small volumes of liquid ( ap

233 LCM-RRBS accurately and reproducibly profiles genome-wide methylation of DNA ext

234 Similarly, ESAs did not reproducibly provide cytoprotection to neuronal, renal,

235 A biomarker is an accurately and reproducibly quantifiable biological characteristic that

236 peptides (corresponding to 37 proteins) were reproducibly quantified based on their relative peak are

237 a acquisition we can consistently detect and reproducibly quantify >4000 proteins from HEK293 cells.

238 use very few in vivo and in vitro models can reproducibly recapitulate the human disease, we generate

239 r melanoma and basal cell carcinoma that are reproducibly recognized among RCM users.

240 aptive immune response, infected BALB/c mice reproducibly recover from infection, consistent with pri

241 P. nitroreducens isolates were reproducibly recoverable from communities after prolonge

242 f schistosomes in the host to patency, as we reproducibly recovered significantly fewer S. haematobiu

243 Our method reproducibly recovers 94.0% of polymorphonuclear leukocy

244 n of beta-catenin with antisense morpholinos reproducibly reduced the expression of 247 mRNAs at gast

245 rate that A673T, a protective allele of APP, reproducibly reduces amyloidogenic processing of APP and

246 A fractured sample of this material reproducibly regains more than 95% of the tensile modulu

247 nterrogations could be run consecutively and reproducibly regardless of the path taken to reach a giv

248 and assessed their ability to accurately and reproducibly report 5hmC profiles in mouse tissues conta

249 cells, the sensor-containing FLNA construct reproducibly reported FLNA domain unfolding strikingly l

250 density is a major alteration that has been reproducibly reported in the cerebral cortex of patients

251 ell clones revealed that AgmTRIM5alpha could reproducibly restrict SIV(mac239) replication, and that

252 uces observable neurological dysfunction and reproducibly results in brain hemorrhages whose appearan

253 is spontaneous (no additional triggers) and reproducibly results in clots in the large veins of the

254 onal baits in the different rice tissues and reproducibly retrieved at least one interactor for 81.4

255 Constrained scattering modeling reproducibly revealed very similar asymmetric solution s

256 ent strategies attempted to date are not yet reproducibly safe or effective.

257 We have developed a method to reproducibly sample breath from small cetaceans, specifi

258 The automatic algorithm accurately and reproducibly segmented three retinal boundaries in image

259 fibroblasts derived from independent donors reproducibly segregated into low, medium, and high IL-6

260 findings, and defining the 17 analytes that reproducibly segregated the patient populations.

261 The aim of this study was to address if HBV reproducibly selects substitutions in CD8 T-cell epitope

262 In contrast, the stroma was easily and reproducibly separated from Descemet's membrane with a c

263 without environmental cycles for up to 3 wk reproducibly showed spatiotemporal waves of gene express

264 ew single-nucleotide polymorphisms have been reproducibly shown to be linked to HCC onset.

265 Calorie restriction has been reproducibly shown to prolong lifespan in various experi

266 aradigm at gamma frequency (~40 Hz) has been reproducibly shown to reduce entrainment as measured by

267 though epitope-specific T cell responses are reproducibly similar at the population level, expansion

268 changes only at ~.2 mK/min to remarkably and reproducibly slow down the drift of tip-substrate distan

269 dendrites, axons, and synaptic terminals are reproducibly specified for each neuron type, yet it rema

270 microbial viability, as demonstrated by the reproducibly strong concordance between assay signal and

271 By reproducibly subtyping achalasia into classic achalasia,

272 Oral immunotherapy (OIT) has demonstrated reproducibly successful desensitization in patients with

273 lphenyl) benzamide (2-MMB) as compounds that reproducibly suppressed the LQT phenotype.

274 , single- or multiple-probe particles can be reproducibly synthesized and used in customizable multip

275 Ad,Me))Co(II)](BPh4) (3) is isolable and was reproducibly synthesized as well as fully characterized,

276 We reproducibly synthesized various derivatives of tetrathi

277 There are facilities for reproducibly tallying, filtering, flagging and annotatin

278 gut, but it remains unclear how rapidly and reproducibly the human gut microbiome responds to short-

279 ust, patterned constructs in oil, which were reproducibly transferred to culture medium.

280 major goals of regenerative medicine are to reproducibly transform adult somatic cells into a plurip

281 ch by episodic hypoxemia or hypotension also reproducibly triggers PIDs.

282 evated corticosteroid levels, due to stress, reproducibly triggers reactivation from latency in the f

283 ity for these ions, with an added ability to reproducibly turn ion-binding on/off.

284 ly 50 observed regulators bind to both genes reproducibly, twice more than in independently expressed

285 MEF) with a conditional Dlc1 knockout allele reproducibly underwent neoplastic transformation.

286 The ability to reproducibly use cells isolated by fluorescence activate

287 treoretinal interface features were assessed reproducibly using a newly developed OCT scan acquisitio

288 We show the technique works robustly and reproducibly using as little as 500 ng of starting DNA,

289 This marker is challenging to quantify reproducibly using quantitative PCR (qPCR) or next gener

290 Interestingly, all glp mutants were reproducibly virulent in the respiratory tracts of the c

291 ard solutions and human serum samples worked reproducibly with close to 100% recovery.

292 The peaks develop well reproducibly with decreasing temperature, thereby highli

293 human plasma as a donor phase were extracted reproducibly with good linearity and a 10-fold improved

294 The thickness increases reproducibly with increasing relative humidity.

295 They can be made reproducibly with robust synthetic protocols, resulting

296 of perineural and intraneural vessels occur reproducibly within particular hindbrain locales.

297 eatment, the H274Y resistance mutation fixed reproducibly within the population.

298 onstrate that laser-pulled quartz nanopipets reproducibly yield not only an extremely small tip diame

299 Our strategy reproducibly yielded high levels of amplification from a

300 report an aptamer discovery technology that reproducibly yields higher affinity aptamers in fewer ro