ライフサイエンスコーパス: requirement of

1 (IRES) can be used to bypass the traditional requirement of a 5' cap and some/all of the associated t

2 nded RNA viruses for bypassing the host cell requirement of a 5' cap structure.

3 evolutionary link between olfaction and the requirement of a ciliary compartment for Hedgehog signal

4 ysteine (N-Cys)-containing peptides, but the requirement of a Cys residue at the ligation junction ca

5 ll clpC allele was unable to suppress the LA requirement of a DeltasufT Deltanfu strain.

6 astic Boolean network models in removing the requirement of a directly observable Boolean state vecto

7 onalize its adoption to meet the physiologic requirement of a fast-acting membrane fission apparatus.

8 ors into biochemical sensor platforms is the requirement of a gate electrode, which imposes restricti

9 rement techniques is often restricted by the requirement of a large amount of cells (Southern-based t

10 allenges in medicine and its management is a requirement of a large diversity of illnesses.

11 A confirmation of the end point or a requirement of a minimal percentage change in albuminuri

12 development and differentiation, without the requirement of a pre-B cell stage in zebrafish.

13 ies on two factors specific to AHAS: (i) the requirement of a reduced FAD cofactor for the enzyme to

14 trategies coupled with the relaxation of the requirement of a single itinerant ion can unlock calcium

15 w a detailed structure-function analysis and requirement of a substructure of U6atac 3' stem-loop in

16 ium ND2006 Cpf1 (LbCpf1) is limited by their requirement of a TTTV protospacer adjacent motif (PAM) i

17 Because of their obligatory requirement of a vertebrate blood meal for reproduction,

18 tion is known to vary with the computational requirements of a circuit, yet how the timing of action

19 eric or electronic properties to fulfill the requirements of a defined catalytic reaction.

20 Here we investigate the sequence requirements of a G-quadruplex that can both bind GTP an

21 Surplus between food availability and requirements of a given country is considered as food wa

22 The ligand requirements of a number of HS-binding proteins includin

23 To meet the requirements of a PoC application and to improve the mea

24 We have studied the minimal fusion requirements of a prototypic phlebovirus, Uukuniemi viru

25 ial to fulfill the homogeneity and stability requirements of a reference material for microanalytical

26 ivity of dlPFC neurons conforms to the basic requirements of a system that performs credit assignment

27 ilability are compatible with the ecological requirements of a target species.

28 ribed to date, this ocellar system meets the requirements of a true polarization analyzer [9, 10].

29 We propose a model explaining the requirement of A2BP1 as a positive regulator of context-

30 Instead, we should reject the requirement of accurate self-awareness for morally respo

31 These results underscore the prevalent requirement of active CRMP2 for optic nerve regeneration

32 echanisms to sustain the normal biosynthetic requirements of actively proliferating tumor cells.

33 procedure is easily implemented without the requirement of additional devices supplementing existing

34 ptibility to HDV but not HBV, indicating the requirement of additional HBV-specific factors.

35 ker-expressing fibroblasts, highlighting the requirement of additional myoblast-derived factors for f

36 The modalities of chemotherapy, requirements of adjuvant instrumental or surgical proced

37 MRs and provide mechanistic insight into the requirement of AFF3 at an enhancer for the expression of

38 Together, these data demonstrate the requirement of AhR for the maintenance of CD49a(+)TRAIL(

39 on both the X and Y chromosomes, which is a requirement of all current methods that determine stratu

40 be utilized to further elucidate structural requirements of alpha-syn fibril growth and to identify

41 from Alzheimer's disease (AD) brain and the requirement of amyloid precursor protein (APP) for these

42 tnatal life to meet the increased functional requirements of an adult.

43 and coimmunoprecipitation to investigate the requirement of associated kinases for functioning and li

44 crease by 65 000, compared with an increased requirement of at least 100 000.

45 The requirement of autophagy in Mincle-mediated NET formatio

46 pression of GFP-AtSAUR19 bypasses the normal requirement of auxin for elongation growth by increasing

47 rties precisely matched to the computational requirements of behavioral learning and suggest major re

48 d either due to limited functionality or the requirement of bioinformatic expertise.

49 To fulfill the different requirements of biomedical applications, different polym

50 ation at sensitivity levels realistic to the requirements of biopharmaceutical research and developme

51 under inflammatory conditions, the intrinsic requirement of Blimp1 for homeostatic maintenance of the

52 This indicated a requirement of BMP-2 for NFATc1 expression in OBs.

53 The requirement of both activities to coordinate proper ovul

54 n with P1 stabilization by SAM, explains the requirement of both SAM and magnesium to form the fully

55 analysis conditions were designed to fit the requirements of both affinity LC and ESI-MS.

56 n contractility reveal a temporally specific requirement of bulk tissue compliance to regulate heart

57 be understood from the differing geometrical requirements of C and Si.

58 terations, in studied males, demonstrating a requirement of C5aR1 signaling for appropriate brain dev

59 Through careful mapping of the ribose requirements of Cas9, we develop hybrid versions possess

60 These results suggest that the requirement of Cat-1 for this hallmark of cellular trans

61 Our studies reveal a novel, cell-autonomous requirement of CBL and CBL-B in epithelial stem cell mai

62 nstrate a mammary epithelial cell-autonomous requirement of CBL and CBL-B in the maintenance of MaSCs

63 tional gene deletion showed a cell-intrinsic requirement of CD28 for CD8 T cell proliferation after P

64 structural changes to Cdk2 that obviate the requirement of Cdk activation loop phosphorylation.

65 m that accommodates the increased functional requirement of Cdk5 activation during neuronal different

66 ssion and indicate a previously unrecognized requirement of cell cycle progression for the activation

67 The requirement of cell-dependent forces to generate FN fibr

68 s to assess cell properties ideally suit the requirements of cell-based therapeutics, since they perm

69 anorexia differentially shapes the metabolic requirements of cellular stress adaptations, leading to

70 stored orange maize to the estimated average requirement of children and women was 26.5% and 24.3%, r

71 rcomplex formation, emphasizing the specific requirement of CL in supercomplex assembly.

72 both classes of CPR all point to the strict requirement of class II CPRs for monoterpene indole alka

73 insight into the processing and trafficking requirements of CMV envelope protein complexes and provi

74 However, the requirement of collecting separate training data for PCA

75 embranes into nanodisk particles without the requirement of conventional detergents.

76 Finally, we find a requirement of coordinated activities between wedging an

77 a retrograde labeling system, we defined the requirement of CSNs in the execution of a skilled foreli

78 of such hybrid materials meeting the crucial requirements of cycling stability and high rate capabili

79 promising nematode penetration, suggesting a requirement of cytokinin signaling in RKN feeding site f

80 ocyte population in juvenile mammals and the requirement of Dab2 in the regulation of Ras/MAPK signal

81 of p53 protein, which can be attributed to a requirement of DCAF1 for MDM2-mediated p53 poly-ubiquiti

82 decrease in proliferation, in line with the requirement of dcSAM production for oncogenicity.

83 However, energy requirements of desalination plants account for half the

84 To genetically dissect in vivo the requirement of different signal transduction pathways em

85 ing mechanisms underlying variable metabolic requirements of different Lyme disease spirochetes withi

86 ve, euchromatic locus but did not bypass the requirement of DIM-7, previously implicated in the local

87 Moreover, based on the requirement of dimerization for strong fluorogen activat

88 ly; P<0.0001) and a significant reduction in requirements of DM medications.

89 However, the spatial-temporal requirement of dpp for growth and patterning remained la

90 pp and characterise the spatial and temporal requirement of Dpp in promoting growth.

91 essential to fulfill the efficacy and safety requirements of drug-based targeted therapy.

92 Here, I consider the unique induction requirements of each M cell subset and functional differ

93 mon tools that are able to handle the varied requirements of each MHC-group.

94 ble mobility to the specific spatio-temporal requirements of each task.

95 ipid accumulation These results indicate the requirement of ecdysone binding to the EcR:RXR:MfR compl

96 This explains both, the puzzling requirement of Egfr in oncogenic Ras-mediated overgrowth

97 ficient animals, demonstrating an autonomous requirement of Eif4a3 in NCCs.

98 These findings indicate novel and essential requirements of EIF4A3 for NCC migration and osteochondr

99 hich reduces the electron density due to the requirement of electroneutrality.

100 In this study, we analyzed the requirement of endogenous Kras to maintain survival of m

101 ence of the water and energy sectors, global requirements of energy for water (E4W) are still poorly

102 ic protection, contrasting with the specific requirement of ERalpha-AF2 in the metabolic actions of 1

103 end-stage liver disease, and to minimize the requirement of exogenously administered insulin for pati

104 ion intensities, degradation in ambient air, requirements of exotic materials or phases, or involveme

105 This leads to the requirement of fast, accurate and reliable techniques fo

106 Requirement of FcgammaR engagement for internalization o

107 ely dissect the isoform- and tissue-specific requirements of foraging's functions and shed light on t

108 We now report the identification and the PIP requirements of four distinct subreactions of PLF.

109 directed siRNA approach, we substantiate the requirement of FoxO6 for a correct radial migration in t

110 roduce in a form that is compatible with the requirements of fragment-based drug discovery, we have d

111 Eligibility included a minimum requirement of FRalpha positivity by immunohistochemistr

112 ecific and germline mutants, we examined the requirement of Frs genes in two FGFR-dependent processes

113 The requirement of functional Slr1270 for protein secretion

114 did not always overlap, indicating distinct requirements of functional stabilization versus antibody

115 To date, the growth and nutritional requirements of fungi during infection, which are releva

116 To meet the design requirements of fusion reactor, the development of the s

117 ur results provide insight into the sequence requirements of G-quadruplexes, and should facilitate th

118 ogether, these data demonstrate the critical requirement of GGAA-microsatellites as EWS/FLI activatin

119 lysis of GANAB-null cells showed an absolute requirement of GIIalpha for maturation and surface and c

120 t in slices from GluA2 KO mice, indicating a requirement of GluA2-containing AMPARs, similar to expre

121 Given the distance requirements of HA, the flexibility of PEG scaffolds is

122 mperature and pressure requirements, but the requirement of heating the input water makes it energy i

123 stillation process, entirely eliminating the requirement of heating the input water.

124 Ms in complex biological systems without the requirement of high mass accuracy instrumentation.

125 ism, buffer-mediated proton transport, and a requirement of high phosphorus content for the rapid gro

126 esolve with pump-probe techniques due to the requirement of high resolution, both in time and pump en

127 of regioselectivity (C3 versus C2), and the requirement of high temperatures, precious metals and th

128 and industrial applications should meet the requirement of high yield, high purity, and high activit

129 lts suggest a trade-off between the opposing requirements of high designability and the likelihood of

130 s far involve challenging aspects, including requirements of high excitation intensities, degradation

131 ases cellular survival both by assigning the requirements of high response speed and high response ac

132 ed: the demands of adjusting to the academic requirements of higher education study; the experience o

133 We assessed the structural requirements of HP activity and excluded that it is a cy

134 The ligand requirements of HS-binding proteins have, however, been

135 Comparing energy requirements of HS-DAC and MEA-PCC, we find that the par

136 The unique requirement of HSP1 for the TFAM tail may enable its reg

137 methodology was used to establish the ligand requirements of human Roundabout receptor 1 (Robo1), whi

138 The requirement of hydrofracking, fast recovery decay and ul

139 Our studies identify the requirement of IFN-gamma stimulation as a mechanism for

140 We sought to define the interaction and requirement of IL-4 and vascular endothelial (VE) IL-4 r

141 olonged survival of islet allografts without requirement of immunosuppression.

142 le to adapt their properties to the specific requirements of individual catalytic transformations.

143 he challenge of understanding the ecological requirements of individuals living in two geographically

144 that contribute to variability in treatment requirements of inner-city children have not been fully

145 Earlier findings have identified the requirement of insulin signaling on maturation and the t

146 rved in ISG15 deficiency is explained by the requirement of ISG15 to sustain USP18 levels in humans,

147 Accordingly, the functional requirement of key transcription factors varies dependin

148 together allowing direction finding with no requirement of knowing the incident sound pressure level

149 egration resembles DNA repair processes, the requirement of known DNA repair pathways for integration

150 , including retardation effects, without the requirement of large computational resources.

151 data from previous mammalian studies and the requirement of light for the activation of LJ001, we hyp

152 sions from AKT/c-Met mice, we determined the requirement of lipogenesis in AKT/c-Met driven hepatocar

153 apses and abolishes potentiation; and (iv) a requirement of long periods of rest for reconstitution o

154 thesis, little is known about the structural requirements of LOXL2 that enable collagen IV crosslinki

155 ethal immune pathology, revealing an ongoing requirement of LUBAC activity for Treg cell homeostasis.

156 The requirement of m(6)A and its reader YT521-B for female-s

157 oduction into the applications and precursor requirements of main group materials will be presented f

158 res and materials combinations that meet the requirements of many critical illumination applications.

159 nregulation of these proteins indicating the requirement of MDM4 to promote p53-mediated transcriptio

160 n inner ear morphogenesis and identifies the requirement of MEKK4 expression in regulating the specif

161 the compatibility of the technique with the requirements of metabolomics and confirms its potential

162 ensure the software's ability to handle the requirements of modern science.

163 universal MSP is inherently aerobic due to a requirement of molecular oxygen for one of the key enzym

164 However, the requirement of momentum matching along the metasurface s

165 The requirement of most prostate cancers for androgen and mo

166 labour for cloning, limited vector capacity, requirement of multiple promoters and terminators, and v

167 ities and differences in the transcriptional requirements of murine effector gammadelta27(+), gammade

168 inetics may subserve the specific functional requirements of neurons in intact circuits.

169 regulated to satisfy the changing metabolic requirements of neurons, but how this is accomplished ha

170 ific immunity and the neutralization breadth requirements of next-generation antibodies, and thereby

171 iated with signalling function, suggesting a requirement of NOPE1 function for presymbiotic fungal re

172 bers, thus unravelling an important cellular requirement of normal Tau.

173 ghts into the molecular mechanism and energy requirements of NSF.

174 Using this approach, we bypassed the requirement of Nup2 for NPC segregation.

175 The use of BPEs removes the requirement of ohmic contact to individual array element

176 racter displacement acts to change the niche requirements of one or both species.

177 gh-throughput technologies has led us to the requirement of ontology representation of cell types and

178 of false positives, and (in some cases) the requirement of opening reaction tubes postamplification.

179 The low computational resource requirement of OrthoReD is achieved by repeating ortholo

180 TS1 is nuclear localized indicating a direct requirement of OsOTS1-dependent deSUMOylation activity i

181 ing of BS/SC without compromising dosimetric requirements of other involved structures for lrNPC.

182 Oxygen requirements of our highest producer were reduced owing

183 lar, comprehensive analysis of the metabolic requirements of ovarian cancer tumor growth has not been

184 As these features resemble the requirements of PAO, we considered membrane-bound Rieske

185 The present work has uncovered a requirement of Pax6 in the development of all rhombic li

186 eep binding cleft and structural recognition requirements of PBPs.

187 an improved understanding of the structural requirements of PDE binding that will be useful in futur

188 We found a functional requirement of PEG3 for TFEB transcriptional induction a

189 multiple signalling pathways, we establish a requirement of Pent for Wg signalling.

190 Compared with an siRNA-like approach, the requirement of perfect complementarity of the microRNA s

191 efficiency of mixing processes owing to the requirement of phase matching.

192 PhotoGate bypasses the requirement of photoactivation to track single particles

193 The biosynthetic requirement of photoreceptors is among the highest in th

194 al for bacterial entry, corresponding to the requirement of PI(4,5)P2 for R. typhi entry.

195 influenza virus replication, and we map the requirement of PLK activity to early stages of the viral

196 on frequency, and validated the differential requirement of Pol4 polymerase at 3' and 5' DSBs.

197 on) solid phase extraction (SPE) without the requirement of pre-methylation for NAs.

198 portance of specific sequence and structural requirements of pre-miRNA for editing along with a sugge

199 n large numbers of optical elements, and the requirement of precise control makes this approach chall

200 iring cost and the representative functional requirement of processing efficiency.

201 The requirement of prophylactic and radical cure activities

202 hip in 1982, because they could not meet the requirement of proving their forefathers settled in Burm

203 July 30, 2013) the Ohio Board of Pharmacy's requirement of PSPs for bevacizumab.

204 Here we dissected the minimal structural requirements of PTIP and its different protein complexes

205 r, between the hardware size and reliability requirements of quantum computing algorithms and the phy

206 o markedly reduce the footprint and resource requirements of quantum information processing systems,

207 ith wearable electronics, there is an urgent requirement of realizing the functional integration of g

208 The requirement of recipient Ly6Chi monocyte recruitment was

209 transitions, possibly due to the high energy requirements of regulation.

210 These data identify the requirement of RIAM for formation of immunological synap

211 unveil an unexpected cell death-independent requirement of RIP kinase activity in coordinating neuro

212 lished the in vivo relevance of NETs and the requirement of RIPK1/3/MLKL-dependent necroptosis, speci

213 fectious diseases without the infrastructure requirements of RNA-Seq technology.

214 In a broad sense, the functional requirement of robust SAC silencing could have helped sh

215 Plants with RCS had reduced nutrient requirement of root tissue for optimal plant growth, red

216 gan dysfunction, recovery of renal function, requirement of RRT after day 90, duration of renal suppo

217 due to limited device sensitivity and/or the requirement of scanning the detection system to form an

218 ored steroidogenic responses, confirming the requirement of SCAP-SREBP2 in steroidogenesis.

219 in vivo instability, short half-life and the requirement of several administrations to obtain a pharm

220 Here we investigate the developmental requirement of Shank3 in mice, a prominent monogenic aut

221 A hitherto unobserved requirement of short-chain lipids in activating the tran

222 A frequent requirement of single cell expression analysis is the id

223 Despite of the urgent requirement of solving the issue, understanding of such

224 hieving a robust CD8+ T cell response is the requirement of spatio-temporal orchestration of antigen

225 The requirement of sub-luminal phase-velocity in laser-drive

226 h has not been utilized because the sequence requirements of such structures are not well understood.

227 due to their scalability and to overcome the requirement of suitably volatile precursors as the techn

228 ubisco, the specialized folding and assembly requirements of Te-Rubisco hinder its heterologous expre

229 over contamination, false positive results, requirement of technical expertise for performance and d

230 breeding efforts to refine the vernalization requirement of temperate cereals and adapt varieties to

231 smatch bubble templates could circumvent the requirement of TFB2M, but TFAM was still required for ef

232 ernal medicine (IM) examination is a central requirement of the American Board of Internal Medicine's

233 Here, we have demonstrated the selective requirement of the AT1A receptor in leptin-mediated cont

234 epresents a novel CIA pathway with a minimal requirement of the CIA-targeting factors and represents

235 The success is however anecdotal due to the requirement of the contact prediction methods for the hi

236 Over-expression of nfu suppressed the LA requirement of the DeltasufT strain.

237 trophy and dilation, supporting a functional requirement of the Nkx2.5+ cardiomyoblasts.

238 activation DeltaG()rot reflects the spatial requirement of the ortho substituent borne by the aryl m

239 tation in PALB2 and directly demonstrate the requirement of the PALB2-BRCA1 interaction for breast ca

240 The water footprint and the land requirement of the solar thermochemical fuel pathway are

241 w, no vertebrate animal model has tested the requirement of the spectrin cytoskeleton in maintenance

242 At5g32470 accumulated ThMP, and the thiamin requirement of the th2-1 mutant was complemented by wild

243 s obtained were found to comply with all the requirements of the animal feed market.

244 ffinity and define the steric and electronic requirements of the binding pocket across the opioid rec

245 that improve dramatically in time and space requirements of the classical algorithm of single popula

246 Examination of the O2 requirements of the CO release step revealed that the SL

247 ns shed light on the energetic and geometric requirements of the different steps of the ihDA/rDA sequ

248 filter was applied to PSF images to meet the requirements of the EANM Research Ltd.

249 domized separately to ascertain the chemical requirements of the encoded amino acids and the morphoge

250 To understand the molecular and structural requirements of the enzymes that favor the biochemical f

251 Here, we test the minimal structural requirements of the Escherichia coli DinJ antitoxin to s

252 uality by over 20% to meet the "good status" requirements of the EU Water Framework Directive with a

253 ssue was prepared and processed according to requirements of the following: in situ hybridization, im

254 sm and energy functions, which reflected the requirements of the germinating and growing embryonic pl

255 ned by antibody specificities and structural requirements of the HIV envelope monomer.

256 in synchrony with the overall developmental requirements of the host.

257 These findings were then compared with the requirements of the IELTS spoken test.

258 address the likely possibility of different requirements of the in vivo environment, we screened 135

259 aoxane-based molecule, E209, which meets key requirements of the Medicines for Malaria Venture drug c

260 The requirements of the molecule include not just the presen

261 ng the contribution of the DCP to the oxygen requirements of the photoreceptors as well as the outer

262 from coated MNs, and thus contribute to the requirements of the regulators appraising these devices.

263 deployed and integrated (or not) to meet the requirements of the sustainability, closed-loop and reso

264 )proteins should be tailored to the specific requirements of the targeted application.

265 to the electronic and, particularly, steric requirements of the trifluoromethyl group in comparison

266 The regulatory framework and the technical requirements of the US biosimilars program involve a ste

267 ing global score estimates, depending on the requirements of the user: (i) ModFOLD6_rank, which is op

268 -induced anaphylaxis were used to define the requirements of the VE IL-4Ralpha and ABL1 pathway in se

269 that is intimately related to the metabolic requirements of these highly active network elements.

270 low energy consumption and modest technical requirements of these ion sources favors their employmen

271 y is the first to demonstrate the structural requirements of these thiosemicarbazones necessary to ov

272 Furthermore, the sequence requirements of these two motifs are significantly diffe

273 id regions, the water footprint and the land requirement of this fuel production pathway are analyzed

274 t their +1 nucleosome, which exemplifies the requirement of this histone for transcription.

275 Importantly, the requirement of this innate immunity arm appears to be ev

276 and ABL1) approaches were used to define the requirement of this pathway in VE barrier dysfunction.

277 ferent bacterial species contain the genetic requirements of this stress response oscillator, we hypo

278 Requirement of three periventricular lesions resulted in

279 re recognized by the single ERfs without the requirement of TMM.

280 asic expression pattern indicates the active requirement of topoisomerase II during these stages of t

281 cs, low stability of the conjugated product, requirement of toxic catalysts, and side reactions with

282 development and clearly defines the stage of requirement of transcription factors key for early ILC d

283 oped a clinical pathway suited to the unique requirements of transfemoral transcatheter aortic valve

284 Defying the requirements of translational periodicity in 3D, rotatio

285 ed PKA activities could partially bypass the requirement of TRI10 for TRI gene-expression and DON pro

286 lls, which varies depending on the metabolic requirements of tumors.

287 TR core domains suggests that the functional requirement of two discrete structural domains is a comm

288 ment of companion studies that establish the requirement of two Plasmodium spp. proteases of the plas

289 Our data further demonstrated the requirement of type I IFN in DNA vaccine-induced immune

290 The requirement of type I interferon (IFN) for natural kille

291 Here, we have tested the requirement of ubi of Dl for signalling.

292 yield of non-fermentable carbon sources, the requirement of ubiquinone correlates with oxidative stre

293 ical approaches, we show that this increased requirement of ubiquinone is to mitigate elevated levels

294 tial goal of this study was to reexamine the requirement of UL21 for herpes simplex virus 1 (HSV-1) r

295 The requirement of various BMP receptors and members of the

296 Finally, we show evidence for the requirement of VASP to form tetramers and provide an ame

297 al fortifiers, may be inadequate to meet the requirements of very preterm infants; in addition, intra

298 The requirement of voltage-gated Na(+) and Ca(2+) channel ac

299 In this report, we sought to determine the requirement of Vpr for facilitating HIV-1 infection of m

300 gether, our studies identify the mesenchymal requirement of YAP/TAZ in the gastrointestinal tract and