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2 depletion reduced the total body irradiation requirement to 100 cGy for establishing stable mixed chi
3 Skp1 modification but also restored the O(2) requirement to a level comparable to that of overexpress
4 y were compared for demographic and resource requirements to a group of non-premature patients by a b
5 hecklist implementation of method validation requirements to a method validation approach that should
7 volume of related FabH enzymes that may be a requirement to accommodate the aromatic substrate 2-ABA.
8 Since its personnel must meet strict visual requirements to accomplish their mission in a variety of
9 sions for myoblast fusion in mammals and its requirement to achieve efficient hypertrophic myofiber g
10 lly critical to evaluate costs and inclusion requirements to achieve a sufficient statistical power o
14 ond-messenger-based system, coupled with the requirement to adapt to changing environmental condition
16 fered contained 125% of the estimated energy requirement to allow self-selection of food quantity.
19 metabolism and genetic variation in nutrient requirements to an involvement in human nutrition and in
20 arranged in a pathway consistent with their requirement to arrest cells at different stages of the c
21 n of foveolar cells and begins to define the requirements to assemble highly specialized organelles a
22 r quantitation limit to meet the sensitivity requirement to assess the pharmacokinetics in a toxicolo
23 xpanding the scope of the current guideline; requirements to assess the risk for development of antib
25 her use of marginal donors is limited by the requirement to assume immediate and full support of the
26 r, because a single transgene is the minimum requirement to attain the ground state, EpiSCs offer an
27 of certification in forested regions, strict requirements to avoid all peat, and routine monitoring o
30 rmulations based on SHSs and PMF met all the requirements to be considered as CBEs; therefore they co
32 vasopressor action, allowing norepinephrine requirements to be reduced from 0.29 +/- 0.15 (SD) micro
34 0%]) endorsed a need to revise current board requirements to better emphasize closing gaps in knowled
35 we propose, are intrinsic to the functional requirement to bind all GU-rich sequences and yet to dis
36 -RNA interface remains mobile, most likely a requirement to bind many GU-rich sequences and yet discr
40 f ferrocytochrome c can be rationalized as a requirement to bury the oxidation-induced positive charg
41 ompare the results with total AIDS financing requirements to calculate the size of the resulting fund
43 F sputum yielded virtually identical fitness requirements to CF sputum, providing support for this me
48 e interval (95% CI) 1.28-2.47, P = 0.001], a requirement to complete missed shifts (OR 3.04, 95% CI 2
49 cle (part two of the series), the regulatory requirements to conduct human research are explained.
51 need to maintain tertiary structure and the requirement to conserve residues more directly involved
52 or NK cell-based therapies and highlight the requirement to consider both MHC class I haplotype and t
53 ayer of complexity to the biology of LSCs: a requirement to consider the effect of the various recurr
54 ociated MUC1, we have identified the minimum requirements to consistently induce CTLs and ADCC-mediat
56 back of current humanization procedures, the requirement to construct and analyze each humanized anti
57 e periplasm into the active site without the requirement to control the timing of opening and closing
58 constraints encountered and the fundamental requirement to control them presented here also should b
59 mmon problems in functional imaging: (1) the requirement to correct for multiple statistical comparis
60 we believe that the introduction of a fixed requirement to corroborate microarray data, especially i
65 We exhaustively analyze dual-RNA:Cas9 target requirements to define the range of targetable sequences
67 need to label the N-glycans, as well as the requirement to desialylate before analysis, and could co
68 atforms as the GIY-YIG domain alleviates the requirement to design two nuclease fusions to target a g
70 ence differs convincingly from zero, and the requirement to detect harms and balance efficacy against
71 e estimates, and compare minimum sample size requirements to detect gene-environment interaction in c
75 he method are commercially available with no requirement to develop novel assay-specific reagents.
76 ue to lack of cleavage at most sites and the requirement to disrupt the outer membrane to identify pe
77 at the entrance of the pore is the dominant requirement to distinguish between two differently charg
78 otein (Mlp1 or Tpr) and RBPs are the minimum requirements to distinguish and retain aberrant mRNAs.
79 o policies advocating centralisation and the requirement to do minimum numbers of surgical procedures
80 tial link of failure to meet this additional requirement to early and age-related cognitive compromis
81 ethod that balances time, space and accuracy requirements to efficiently extract frequent k-mers even
83 vide important insight for understanding the requirements to elicit and maintain durable tumor immuni
84 hibit hierarchical Sit4 and PP2A phosphatase requirements to elicit nuclear Gln3-Myc(13) localization
85 y human volunteers, we manipulated subjects' requirement to emit or withhold an action independent fr
86 lties associated fluorescence assays such as requirements to engineer fluorogenic reactions and false
87 and suggest that its export from the ER is a requirement to ensure steady-state maintenance of the or
88 on levels of the pathway constituents, a key requirement to ensure the functionality of individual ce
89 nternational Health Regulations outline core requirements to ensure the detection of public health th
90 process of BTV is similar in specific lipid requirements to enveloped viruses that enter cells throu
91 alysis, allowed us to identify its metabolic requirements to establish infection, including the abili
92 the USA and discuss the need for regulatory requirements to establish the performance characteristic
93 d population-weighted estimated average zinc requirements to estimate the risk of inadequate zinc int
96 e column; this is in stark contrast with the requirement to evaporate acid anhydrides by nitrogen pri
97 o make the cobalt center more "Co1+-like", a requirement to facilitate heterolytic Co-C bond cleavage
99 ds the concept and breadth of the analytical requirement to facilitate the provision of data from 'in
100 157 remaining probands had similar treatment requirements to familial type 2 diabetic subjects but pr
102 impaired semantic cognition when there was a requirement to flexibly shape conceptual activation in l
103 p27 is largely determined by the functional requirement to form a specific intermolecular interface
104 conserved structure of Xenopus NO38 and its requirement to form dimers and pentamers via its N-termi
105 he consequential significance and structural requirements to form the dimerization interface have yet
106 f the polycationic amines and their basicity requirements to fulfill outer membrane destabilization r
107 how here that Bright has multiple contextual requirements to function as a transcriptional activator.
108 based vector systems has been limited by the requirement to generate EBNA+ cells which are 'permissiv
109 ution of sampling effects, introduced by the requirement to globally amplify the single cell mRNA pop
110 robust blood product supply is an essential requirement to guarantee optimal patient care in modern
111 high level of scientific reasoning, and the requirement to have an intuitive and easy to use tool wh
113 eptor and donor fluorophores, as well as the requirement to image large numbers of individual molecul
114 query interfaces, based on user feedback and requirements, to improve usability and service interoper
118 t trigger perforin killing and the signaling requirements to induce FasL expression are distinct.
120 nd CTLA4-Ig on diabetes development, and the requirements to induce tolerance in nod.scid mice after
121 ral selection, which relate metabolic energy requirements to information gain under optimal condition
122 ostulating this protein has a more stringent requirement to initiate DNA strand exchange from the P s
123 l control of transcription, as well as their requirement to initiate or maintain transcriptional acti
125 he need for extensive modular backup and the requirement to integrate transcriptional inputs of multi
127 res are highly divergent, perhaps reflecting requirements to interface with divergent nuclear and cyt
129 ied a series of word-picture pairs under the requirement to judge which of the denoted objects was sm
130 Accuracy, residency, and a study-imposed requirement to limit HIVST to one test per year were mon
131 timulus to an antiviral response, implying a requirement to limit the misrepresentation of self nucle
132 e rDNA and correlates mechanistically with a requirement to load RPA and Rad52 onto chromatin genome-
133 hat enabled the application of international requirements to local settings, with high quality of dat
134 d in polarized B cells are distinct from the requirements to localize to virological synapses in tran
136 an be clinically identified by a vasopressor requirement to maintain a mean arterial pressure of 65 m
137 lidocaine, AL) and AL with Mg (ALM) on fluid requirement to maintain a minimum mean arterial pressure
139 at the evolution of NS5 is restrained by the requirement to maintain function of two enzymatic activi
140 cardiomyopathic phenotype, underscoring the requirement to maintain high respiration rates in the he
143 to promote tissue growth is at odds with the requirement to maintain the stem cell/progenitor cell po
150 lethal mutations, deep fitness valleys, and requirements to make the right amino acid substitution i
151 nologies to confirm the fulfillment of basic requirements to make them attractive for future users.
152 s that I-BmoI has evolved exquisite cleavage requirements to maximize the potential to spread to vari
153 ddressed, and underlying these themes is the requirement to measure quality of life with a new diseas
154 ensitivity, selectivity, and low sample size requirements to measure circulating BoNT activity at mul
157 e compared to baseline food production, land requirements to meet basic caloric requirements, and gre
158 mbraces continual transformation of training requirements to meet evolving clinical needs and public
159 r, certain pathogens; and, on the other, the requirement to minimize immunopathology and autoimmunity
161 Results are discussed in the context of a requirement to modulate the activity of the DNA-binding
162 The institutional review board waived the requirement to obtain informed consent and approved this
163 oved this retrospective study and waived the requirement to obtain informed consent from patients.
200 approved by an ethics review board, and the requirement to obtain informed written consent was waive
207 participation may occur in part because the requirement to opt-in or opt-out results in large differ
209 herapeutic vaccination against cancer adds a requirement to overcome tolerance and to activate a weak
211 tio of key clinical faculty to fellows and a requirement to perform 50 therapeutic bronchoscopies.
213 cing the complexity, time, and sample volume requirements to perform neutrophil chemotaxis assays.
214 esting NK cells display stringent activation requirements to perform this novel, DC-mediated, "helper
215 supplementation in doses greater than daily requirement to placebo on the outcome of mortality in pa
216 his review aims to elucidate the fundamental requirements to possibly improve the Emergy evaluation b
217 use for this purpose has been obviated by a requirement to precondition the host with what would be
218 n inform future correlations and measurement requirements to predict NP attachment in the presence of
219 he limited supply of (225)Ac, high technical requirement to prepare radioimmunoconjugate with very sh
220 ium is insufficient to meet basal myocardial requirements to preserve cellular membrane stability and
223 , the protection of which may be a universal requirement to prevent meiotic genome rearrangements tha
225 rx-1 overexpression also lowered the insulin requirement to prevent severe hyperglycemia in STZ rats.
226 y source of insulin-producing tissue and the requirement to prevent this tissue from being destroyed
230 onformational) mutp53s can override the Cdk2 requirement to promote replication by facilitating the T
231 ure to prevent skin cancer may conflict with requirements to protect bone health through adequate vit
232 lities of low-resource care provision (eg, a requirement to provide 'free' care to certain population
234 0 or better in at least 1 eye (visual acuity requirement to qualify for an unrestricted driver's lice
235 fulfilling critical numerical and biological requirements to quickly generate a DLI product ex vivo u
239 A common bottleneck in such pipelines is the requirement to read, write, sort and compress large BAM
241 The recent shale gas boom combined with the requirement to reduce atmospheric CO2 have created an op
242 ability to produce food, as will the urgent requirement to reduce the impact of the food system on t
243 e trials described were conducted before the requirement to register them was implemented, they are n
245 use of contextual information along with the requirement to remember the "what" and "when" components
247 9 influenza A (H1N1) (pH1N1) activity, and a requirement to report hospitalized influenza cases provi
248 ate of world so as to select actions, is the requirement to represent the uncertainty associated with
249 eakening of the middle crust is an essential requirement to reproduce the observed rift evolution.
250 eded to elucidate the "minimal physiological requirements" to reproduce significant observable phenom
251 el of bistability by bypassing noise and the requirement to resolve individual processes in the loop.
254 model is used to forecast electrical energy requirements to scale up the PV industry and determine t
265 e aim of this work is to determine necessary requirements to successfully apply data analysis strateg
268 nifying theme for all three oncogenes is the requirement to suppress ROCK, which may act as a gatekee
269 large dynamic range without compromising the requirement to suppress transcription, is determined by
270 ite uptake sufficient for the stoichiometric requirement to sustain observed growth, (2) overflow met
272 ium tuberculosis and Leishmania major is the requirements to sustain memory/effector Th1 cells in viv
273 Here we show that cells can leverage these requirements to switch the recycling of the beta-2 adren
274 g/number limits, "fail-first" protocols, and requirements to switch to generics, were associated with
275 activation on a tumor cell, independent of a requirement to target and block complement inhibitor exp
276 y of uncharged side chains of varying steric requirements to test the hypothesis that this residue is
277 abel-free methods such as BLI and SPR is the requirement to tether one of the interaction entities to
278 the zwf binding site converts its positional requirement to that of the fpr binding site in its norma
282 VOCs, for which there are existing reporting requirements to the NPRI, were not included in the facil
283 learnt routes might incur additional memory requirements to those needed for performing a route, and
284 that in certain sensory organs, in which the requirement to transduce specific environmental signals
286 or a DNA polymerase reaction is an important requirement to unambiguously determine the identity of t
288 blem in muscle modeling and, more broadly, a requirement to understanding the connection between musc
290 evolution has been limited by the technical requirement to use global mutagenesis or introduce DNA l
291 0,488 elicited antinociception; however, the requirement to use higher doses in morphine- than saline
293 producing component actions, but without the requirement to use the demonstrated sequential procedure
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