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1 reated with a minimal amount of intervention requiring 1 or 2 anti-vascular endothelial growth factor
2 of the population in Europe and the USA and requiring 1-3% of health-care expenditure as a result of
3 who presented for noncardiothoracic surgery requiring 2 hours or more of general anesthesia with mec
4 annel blocker) produced synergistic effects, requiring 45% fewer spores to kill half of the mosquitoe
5 ), achieved 87.1 +/- 6.0% and 68.4 +/- 14.6% requiring 5.8 and 13.9 kWh kg N(-1) recovered, via absor
6 ns with known answers and open questions all requiring a "yes" or "no" thought using frontocentral ox
7 opically heavier than the modern atmosphere, requiring a biologic cycle with nitrogen fixation, nitri
9 critical step in nervous system maturation, requiring a carefully timed reorganization and refinemen
10 iderable changes in the cell's surface area, requiring a constant adaptation of the cell's plasma mem
12 patients with missing data (n = 4) and those requiring a glaucoma-related secondary surgical interven
13 and different positions within those genes, requiring a large number of evolutionary parameters that
16 sequent deposition of the PbS QD ink without requiring a post-deposition annealing treatment for solv
17 specificity by accounting for normal aging (requiring a significant negative slope that was more neg
19 gories such as objects and phonemes, thereby requiring a solution to the cue combination problem by m
22 rotein-DNA interactions is more challenging, requiring absolute measurements with a relatively high d
26 ndrial and synaptic dysfunctions in a manner requiring activation of autophagy receptor OPTN or NDP52
27 net charge equals the number of basic sites, requiring additional protonation at nonbasic residues.
29 ts geographic areas and clades most urgently requiring additional systematic study-an important pract
31 sits or hospitalizations, particularly those requiring admission to an intensive care unit involving
32 A minority of U.S. states have legislation requiring AED placement in schools, and even fewer provi
33 atures that have not yet enacted legislation requiring AEDs in schools may look to neighboring states
34 motion through an NPR-19-independent pathway requiring an alpha2A-adrenergic-like octopamine (OA) rec
36 ave an advantage of tissue expansion without requiring an external silicone membrane, and thus, they
37 2.19; 95% CI, 1.16-4.11) had greater odds of requiring an ophthalmology referral compared with white
38 quisition of skilled behaviors occurs later, requiring anatomical changes in neural circuitry to supp
44 e implanted was slightly smaller in patients requiring AVR+ARE versus AVR (23.4+/-2.1 versus 24.1+/-2
46 avoidance, and the ability to perform a task requiring basic image recognition were restored up to 13
47 verwhelm attackers, creating an Allee effect requiring beetles to attack en masse to successfully rep
49 defines a novel mechanism of MAPK activation requiring binding of an activator and also shows that MA
50 through mechanisms that extend beyond those requiring binding to the beta1 integrin subunit NPxY mot
52 parties with information-theoretic security, requiring both quantum digital signatures (QDS) and quan
53 month to less than 18 years old, procedures requiring cardiopulmonary bypass, no preexisting renal d
54 r outcomes examined in South Indian patients requiring cataract surgery, PEX was associated with high
57 CRT) is a common complication among patients requiring central venous access as part of their medical
59 erlying the regulation of MCU, in conditions requiring chronic increase in energy production, such as
61 concentration profiles may all produce data requiring considerable along-track averaging for meaning
63 iring vasoactive support, conduit disruption requiring covered stent (n=2), and acute RV dysfunction
64 nting for transfers, 39.8% of rural patients requiring critical resources were cared for in major tra
65 degradation-defective mutants via a pathway requiring cytosolic pattern recognition receptors and NF
67 generated vast amounts of analysis results, requiring development of novel tools for data visualizat
69 The selective predictive role of insulin-requiring diabetes was independent of potential confound
70 AKIN 2/3: HR, 2.22; CI, 2.04-2.41), and AKI requiring dialysis (AKIN 1: HR, 2.59; CI, 2.29-2.92; AKI
71 990 and 2012, with 82 (22%) experiencing DGF requiring dialysis (DGF-D) in the first 72 hours after t
73 on, defined as no immediate function but not requiring dialysis, was associated with adjusted hazard
77 ablished COPD) as acute respiratory symptoms requiring either antibiotics or systemic steroids, and s
78 ines if a patient's pain is life-threatening requiring emergency intervention/surgery or due to some
79 CCY) after an episode of choledocholithiasis requiring endoscopic retrograde cholangiopancreatography
83 The endoplasmic reticulum kinase inositol-requiring enzyme 1 (IRE1) and its downstream target X-bo
84 temper the ribonuclease activity of inositol-requiring enzyme 1 (IRE1) under temporary ER stress.
87 ithelial cells on activation of the inositol-requiring enzyme 1alpha (IRE1alpha)-active spliced X-box
90 ivated (PKR)-like ER kinase (PERK), inositol-requiring enzyme-1alpha (IRE1alpha), and activating tran
92 96.9%-99.3%), reducing the number of infants requiring examinations by 34.3% if only high-risk infant
94 more effective training approaches for those requiring expert perceptual skills or those in need of p
97 RETATION: Two simplified antibiotic regimens requiring fewer injections are equivalent to a reference
98 t homeostasis is a tightly regulated process requiring finely tuned complex interactions between diff
99 in the real world presents the challenge of requiring flexible yet prompt behavior, a balance that h
101 action in the resulting metabolic phenotype, requiring further examination of altered met abolic path
107 ndergoing noncardiac surgical procedures and requiring general anesthesia with endotracheal intubatio
108 eriod, conditional on the effects of Suc and requiring GI These findings reveal that Suc affects the
109 ecurrent monomorphic ventricular tachycardia requiring >/=2 implantable cardioverter-defibrillator sh
110 with biopsy-proven myeloma cast nephropathy requiring hemodialysis treated at 48 French centers betw
111 ecipients experienced delayed graft function requiring hemodialysis which was discontinued on postope
113 teomics, in particular, single cell analysis requiring high sensitivity and ultra-low limits of detec
114 asizing tumor models still poses a challenge requiring highest sensitivity and excellent contrast.
115 t play a crucial role in cognitive processes requiring Hip-mPFC interactions, including spatial navig
116 A concordance analysis of SNPs and INDELs requiring homozygosity unique to all unilateral and bila
118 an asthma exacerbation in the prior 3 months requiring hospital attention, oral corticosteroids, or b
119 ta are available on the etiology of diarrhea requiring hospitalization after rotavirus vaccine introd
120 ry end points were the rate of exacerbations requiring hospitalization and the rate of exacerbations
121 polizumab approximately halved exacerbations requiring hospitalization and/or emergency room visits c
122 Acute decompensated heart failure (ADHF) requiring hospitalization is associated with high postdi
126 strated, with currently available approaches requiring human intervention to compensate for cell move
127 r hydroisomerization of n-hexane, a reaction requiring hydrogenation/dehydrogenation and moderate to
128 sk of DCGF; however, later-onset dysfunction requiring IBx had far greater impact (HR = 13.8, P < .00
132 cancer (requiring ICU), end-stage dementia (requiring ICU and transitioned to comfort-care), intraab
133 failure, cardiac arrest, metastatic cancer (requiring ICU), end-stage dementia (requiring ICU and tr
135 tivity for type 1 ROP, reductions in infants requiring imaging or examinations, numbers of imaging se
136 least 1 lower respiratory tract symptom not requiring immediate antibiotic treatment and with no his
137 iac, allergic, or neurological complications requiring immediate intervention and that led (or could
138 travel time for nondiscretionary conditions requiring immediate medical care decreased by 0.9 minute
139 based global proteomics experiments, without requiring in-depth knowledge of statistical programming.
142 s with AF, the sole presence of diabetes not requiring insulin did not imply an increased thromboembo
143 complicates the clinical course of patients requiring intensive care as a result of their primary me
144 adult patients with anti-NMDAR encephalitis requiring intensive care is good, especially when immuno
145 characteristics of patients with cellulitis requiring intensive care treatment are poorly defined.
146 fluid embolism, hysterectomy), complications requiring intensive care unit admission, and maternal de
150 r more patients), if there were prior alarms requiring intervention (5.5 minutes [95% CI, 1.5-9.5] vs
151 er rates of retroprosthetic membranes (RPMs) requiring intervention (P = 0.049) and less vision loss
152 11 patients (27%) experienced a complication requiring intervention, and there was 1 peri-operative m
157 y countless critical roles in the cell, each requiring it to be activated at a specific location and
158 nces in care, the mortality rate in patients requiring kidney replacement therapy remains approximate
161 dies, bispecific antibodies, and Fc fusions) requiring lack of effector function or elimination of bi
162 applied a lateral elastic load to the object requiring large grip forces for reaches to targets eithe
163 reated, can progress eventually to cirrhosis requiring liver transplantation (LT) before the age of 4
164 used to allocate livers to patients with HCC requiring liver transplantation (LT) but do not include
165 reduced mortality and the number of patients requiring liver transplantation, but more screening camp
166 romise for artificial photosynthetic systems requiring long-lived reduced states to perform multi-ele
169 but some patients remain severely disabled, requiring long-term immunotherapy and/or antiepileptic m
176 ility or death), and time course of bleeding requiring medical attention by face-to-face follow-up fo
177 hina, South Korea, and Japan, and infections requiring medical attention result in death in as many a
178 , and the number of annual anisakiasis cases requiring medical attention was predicted between 7,700
179 with central nervous system injuries, injury requiring medical care in the past 2 years and/or result
180 e processes occur in specialized organelles, requiring membrane-bound intracellular transporters to p
181 e multiple independent steps, with each step requiring method customization and adjustment of multipl
183 ness will remain uncertain in the absence of requiring monitoring data be collected by third-party or
185 ure clinical trials and to identify patients requiring more or less aggressive therapy and additional
186 galactosyl substitution of beta-1,4-galactan requiring more than three backbone residues for optimize
189 gned high-risk status to 420 of 420 patients requiring neurosurgical intervention (sensitivity, 100.0
190 in assigning "high-risk" status to patients requiring neurosurgical intervention among a cohort of 1
191 intervention identified 108 of 111 patients requiring neurosurgical intervention to yield a sensitiv
192 his same cohort, identified all 111 patients requiring neurosurgical intervention, yielding a sensiti
193 anufacturable and testable on a wafer scale, requiring no cleaved facets or special mirror coating to
195 s of persistent outdoor malaria transmission requiring novel measures for surveillance and control.
196 o elongation complexes, patrolling for those requiring nucleolytic rescue, and its short residence ti
199 ently robust, with extremely low backgrounds requiring only 1/10th the sequencing depth as ChIP, mak
201 element for compact two-electron spin qubits requiring only a single dot and no additional magnetic f
205 r provides a simple home page for basic use, requiring only two files in Protein Data Bank (PDB) form
206 e declines in habitat availability for fauna requiring open vegetation structure (such as migratory b
207 esonide versus placebo, severe exacerbations requiring oral or systemic corticosteroids were reduced
209 e immunosensor fabrication process was fast, requiring overall 45min to be completed before analyte s
210 nts a possible solution to this challenge by requiring overexpression of two separate ligands for loc
213 rexanolone as an adjunctive therapy for SRSE requiring pharmacological coma for seizure control.
215 from all surfaces, with CaP and SLA surfaces requiring power setting of 1.0 to 1.5 W for ablation of
216 -six patients with PDR-related complications requiring PPV were prospectively randomized into 1 of 2
219 because the patient may be acutely unstable, requiring prompt intervention, often by a practitioner w
221 structural and biophysical techniques, many requiring protein overexpression to reach sufficient qua
222 antiplatelet agents, had a medical condition requiring proton pump inhibitor treatment, or had alread
223 mpounds from multicomponent samples, without requiring pure compound synthesis, or complex mathematic
224 ion-nonselective channels, with VF induction requiring PVEM overlap with the trailing edge of a norma
227 for a variety of technological applications requiring reliable actuation and high degree of control.
229 HM3 group demonstrated less pump thrombosis requiring reoperation (0 versus 36 points, P<0.001) or m
231 uent than in adults, coronary artery disease requiring revascularization may develop in children beca
236 atients receiving an isolated LVAD, patients requiring RVAD had decreased 1- and 6-month survival: 78
238 targeting of recognition specificity without requiring significant alteration of the surrounding prot
239 l tool, aiding a wide range of applications, requiring single-cell level co-administrations of multip
240 aquatic bodies are becoming more stringent, requiring some treatment plants to reduce effluent nitro
242 ronal signaling is highly compartmentalized, requiring sophisticated transfer mechanisms to convey an
243 are based on morphological characteristics, requiring specialists and being very time-consuming.
245 otal of 60 patients with multivessel disease requiring staged procedure at 1 month were treated with
246 unwanted variation are present in the data, requiring substantial time and effort to be spent on pre
247 struggle with the many-to-one design space, requiring substantial user interaction and the necessity
248 d point was the number of patients no longer requiring surgery at Week 25 based on a composite end po
250 patients with drug-resistant focal epilepsy requiring surgery, hippocampal sclerosis was the most co
252 tive nationwide cohort study of every infant requiring surgical intervention for NEC in the UK was co
254 >/=14 days of life, congenital heart disease requiring surgical repair at <7 days of life, lethal chr
255 ciated with the development of idiopathic MH requiring surgical repair with vitrectomy among a large
257 re difficult to use for exploratory analyses requiring systematic changes to the software or paramete
259 ly present in natural water sources, thereby requiring the addition of iron which complicates the tre
261 with a specific biological function in mind, requiring the chemical incorporation of bioactive factor
262 Our findings are relevant to any activity requiring the coordination of several people, as in musi
263 g these pathogens have become more frequent, requiring the development of new drugs and a better unde
264 lity in materials is traditionally viewed as requiring the discovery of new chemical compositions thr
265 cofactor-containing extracytoplasmic domains requiring the dual action of the co-translational Sec an
266 s evoked during an expression matching task, requiring the judgment of emotional congruence between s
267 n available in the negative-ion mode without requiring the lipids to be ionized directly in both ioni
268 -canonical, involving a regulatory mechanism requiring the OmpR cognate kinase EnvZ, but not OmpR pho
269 sion framework was applied to each question, requiring the panel to evaluate and weigh the importance
270 xture, and both exhibited lipid selectivity, requiring the presence of negatively charged lipids for
271 xquisite example of morphogenetic apoptosis, requiring the receptor protein tyrosine phosphatases (RP
272 A simplified scheme is proposed for samples requiring the separation of Sr, Pb, Nd, and Hf only.
273 to the development of inhibitory antibodies, requiring the use of bypassing agents such as factor VII
274 onists show relatively low efficacy in vivo, requiring the use of high doses that often cause adverse
275 ethodology explicitly seeks novel behaviors, requiring their absence during the first 5 y of the stud
278 g site on TcdB extends into the CROP domain, requiring three short repeats for binding and for full t
280 quantifying these processes is a challenge, requiring tracking of rapidly moving, sub-diffraction ob
281 easure the incidence of bleeding (blood loss requiring transfusion or intracranial hemorrhage) and th
282 r children (aged </=6 years) and adolescents requiring transition of care from child to adult service
283 OP or worse (92% vs. 84%; P = 0.04), and ROP requiring treatment (89% vs. 79%; P < 0.01) was better f
284 or 28 days or more; and one or more symptoms requiring treatment according to the Groupe d'Etudes des
285 and most cases of posterior and panuveitides requiring treatment are treated with corticosteroids and
286 and a history of at least two exacerbations requiring treatment in the previous 12 months before scr
288 ease or asymptomatic viremia (>/=1000 IU/mL) requiring treatment were identified by chart review.
289 or refractory chronic lymphocytic leukaemia requiring treatment who had measurable lymphadenopathy b
291 of recurrent gastroesophageal reflux disease requiring treatment, diminishing some of the benefits of
293 hase 3 trial if they had symptomatic disease requiring treatment; had received, at most, two inductio
294 sociated with increased risk of perforations requiring tympanoplasty, which appears to be further exa
297 including pulmonary hemorrhage, hypotension requiring vasoactive support, conduit disruption requiri
298 Prep is heterogeneous, with 40% of molecules requiring virtually no mechanical force to unfold (<10 p
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