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1 ions with major complications and failure-to-rescue.
2 ng of ARHGAP21 enhanced Cdc42 activation and rescued aberrant morphogenic processes of PTEN-deficient
6 resistant Plk4 can enhance Aurora A-mediated rescue, and, accordingly, Plk4 can phosphorylate and pot
7 s study, we determined that IL-12 disruption rescued angiogenesis and arteriogenesis in type 2 diabet
11 L rescues T cell ICOS surface expression and rescues, at least in part, T follicular helper numbers a
12 (75 mg/kg/day), repeated doses of peramivir rescued BALB scid mice from lethal challenge with BR/08,
13 of a kinase-dead mutant of PERK (PERK-K618A) rescues BDNF and PSD95 levels in the pericontusional cor
14 and cognitive stimulation, is sufficient to rescue binocular matching to the level seen in unmanipul
18 a Nf1 gene deletion extends the response and rescues both neurogenic and behavioral deficits in mice
19 agnosed with asthma, (2) prescribed at least rescue bronchodilator, and (3) had the first visit to th
20 and indicate that the mitochondrial failure rescue by cardiolipin manipulation may be a new intrigui
21 cal signaling; its disruptive effects can be rescued by a constitutively active UNC-9::GFP protein, d
27 paired diabetic BMPC angiogenic function was rescued by adenovirus-mediated expression of IRE1alpha b
29 roduction were weak and could only partly be rescued by blockade of the programmed death 1 pathway.
34 be recapitulated by overexpressing upd3 and rescued by deleting upd3, highlighting a crucial role fo
37 formation, inhibited by EZH2 depletion, was rescued by ectopic expression of EZH2 but not by TRIM28
41 25a and IR76b mutant flies can be completely rescued by expression of respective transgenes in sweet
46 c transmission in aged mice can be partially rescued by improving calcium buffering, or decreasing ac
48 In contrast, eCB-LTD in PE animals was not rescued by increasing presynaptic activity, which actual
50 h during glucose deprivation, which could be rescued by inhibition of rRNA processing or ER stress.
52 ep-timing, phenotypes could be reproduced or rescued by knocking out or restoring BMAL1 exclusively i
55 poietic stem cells, which were significantly rescued by nucleotide supplementation or after depletion
58 ive ACh application at RMPs were immediately rescued by pairing mAChR stimulation with subthreshold d
59 activity present in Disc1 deficiency and was rescued by pharmacological blockade of adenylate cyclase
60 f the sub-synaptic reticulum, which could be rescued by pre- but not postsynaptic expression of unc-1
67 IFN-gamma production defects were partially rescued by supplementation with glutamine, which require
77 promotes blastema accumulation, it does not rescue cell differentiation, indicating that macrophages
79 These findings suggest that mechanisms for rescuing cell division when the biochemical activity of
81 n K, or treatment with calcineurin inhibitor rescued cells from high-glucose triggered oxidative stre
83 we show that increasing brain p62 expression rescues cognitive deficits in APP/PS1 mice, a widely use
86 njection of the antioxidant N-acetylcysteine rescued defective follicle and oocyte development result
89 ds or pyruvate for mitochondrial respiration rescued differentiation in autophagy-deficient neutrophi
93 nose and eye were 0 and 1 point without any rescue drugs, accounted for 9 and 24% of total SLIT, res
94 7,8-dihydroxyflavone hydrate, significantly rescued dye visual function ( 58 fold increase in OKR, p
95 this process is further substantiated by the rescue effect of the tyrosine kinase inhibitor genistein
96 the three NPF domains within GFP-FIP2(S227E) rescued Eps15 localization at the lateral membrane and r
101 identification of proteins whose suppression rescues F508del-CFTR function in bronchial epithelial ce
103 elevant animal models, and robust functional rescue from gene augmentation therapy support future wor
105 mice normalizes lysosomal protein levels and rescues FTLD-related behavioral abnormalities and retina
112 granule cell layer of the dentate gyrus and rescues hippocampal memory defects in a mouse model of K
113 vo with N-acetylcysteine reduces ROS levels, rescues HSC cycling defects, and partially mitigates HSP
114 models, TRAP1 overexpression is protective, rescuing HTRA2 and PINK1-associated mitochondrial dysfun
115 s only in airway epithelium is sufficient to rescue IL-13-induced AHR, inflammation, and mucus produc
116 ose chemotherapy with haemopoietic stem-cell rescue improves event-free survival in patients with hig
117 ieved from the mated female uterus partially rescue in vitro fertilization (IVF) that failed with epi
120 4/aP2 inhibitor-treated cells, but partially rescued in FABP4/aP2-null macrophages when UCP2 is silen
123 and cannabinoid-dependent inhibition can be rescued in npr-19-null animals by the expression of a hu
125 st, defects in substrate specificity are not rescued in the double mutant, implying that functional s
127 Cs, and that P2X5-deficient OC maturation is rescued in vitro by addition of exogenous IL-1beta.
128 nd built environment factors associated with rescue inhaler use and to determine whether these findin
130 teraction prevents Numb from binding Notch1, rescuing it from Numb-mediated lysosomal degradation.
131 tion or silencing of ROCK1 was sufficient to rescue keratinocyte adhesion and biochemical differentia
132 s repression by providing MHV68 RTA in trans rescued KLKI MHV68 replication in tissue culture and ena
134 sites using the DR5 promoter fails to fully rescue lfs plants, suggesting that additional, auxin-ind
135 ipid synthesis, as overexpression of SREBP-1 rescues lipogenic defects associated with OGT suppressio
137 l Wnt signaling, or the DKK inhibitor IIIC3a rescued mandibular molar tooth morphogenesis in Inhba(-/
142 of pain and the time until patients required rescue medication, both showing statistical significance
144 entia mice, both drugs were neuroprotective, rescued memory deficits and reduced hippocampal atrophy.
152 ears to use two synergizing modules, the p53 rescue motif described here and a globular-structured SU
153 ellular PPIA, MM218, given at symptom onset, rescued motor neurons and extended survival in the SOD1(
155 T cells with metabolically active L-cysteine rescued mTOR activation and proliferation but not autoph
156 dicates that exogenous gdf3 is able to fully rescue mutants only when co-expressed with endogenous No
157 , restricting Hdac3 to the nuclear periphery rescues myogenesis in progenitors otherwise lacking Hdac
159 pam + haloperidol group required less median rescue neuroleptics (2.0 mg) than the placebo + haloperi
161 ing-deficient IkappaBDeltaN transgenic mouse rescues NKT cell development and differentiation in this
162 pectedly, expression of mature HMR failed to rescue not only the plastidial but also the nuclear defe
164 n DA neurons and terminals, resulting in the rescue of aberrant striatal DA dynamics, reversal of cha
165 pplication of a KOR antagonist provides full rescue of both LTP induction and dopamine release during
166 he population can actually contribute to the rescue of cooperation, in a clear illustration of how ec
172 ociated virus vectors robustly sustained the rescue of rod function and preserved retinal structure i
174 and Parkinson's disease, and show a partial rescue of the Parkinson's phenotype through drug treatme
175 if in the C-terminal region of Vif indicated rescue of the protein from cyclin F-mediated down-regula
179 al landscapes, to rescuers during search and rescue operations in disaster zones, and to genetic comp
181 hesized that C/EBPalpha overexpression might rescue osteoclastogenesis in cells expressing the mutate
183 Sup35 decreases stop codon read-through and rescues oxidant tolerance consistent with this model.
184 ise(-/-) double-mutant mouse embryos exhibit rescued palatal shelf elevation/reorientation, accompani
185 or global overexpression of SLP-2 transgenes rescued parkin mutant phenotypes, in particular loss of
186 ficial in two distinct clinical settings: to rescue patients from the high risk for death associated
188 facilitated mutant myocilin degradation and rescued phenotypes in a transgenic mouse model of heredi
189 ubstitution of leucine 150 to a serine fully rescued pmr1 Mn-sensitivity at all concentrations tested
192 ible-AMS reporter was created for functional rescue, protein expression pattern analysis, and to dist
193 clinical pathway could impact the failure-to-rescue rate after cytoreductive surgery (CRS) for perito
198 BC1D5 depletion in autophagy-deficient cells rescues retromer recruitment to endosomal membranes and
201 Inhibition of focal adhesion kinase (FAK) rescued SERT function in synapses of KI mice, demonstrat
205 al induction of protective stress genes, and rescues stress sensitivity of TDP-43-expressing animals.
211 that inhibition of p38, but not ERK or JNK, rescue T cells from undergoing peripheral deletion both
213 clone system from which infectious virus was rescued that replicates in human and mosquito cells with
214 increase of Lsd1 expression is sufficient to rescue the age-related transition of beige adipocytes to
215 ocytic function of ARPE-19 cells, as well as rescue the cells from the phagocytic dysfunction induced
216 yltransferase activity and on its ability to rescue the cold-growth inhibition of a Saccharomyces cer
218 ia, whereas a constitutively active Rac3 can rescue the deficits in invadopodium function in Vav2-kno
219 iR-9, and overexpression of miR-9 can partly rescue the effects of Dicer1 deletion on the MG phenotyp
222 NIH 3T3 mouse fibroblasts and of WT KRAS to rescue the growth defect of mouse embryonic fibroblasts
223 ession of VEGF-A165 b alone is sufficient to rescue the increase in proteinuria, as well as glomerula
224 te EIN2 C terminus (EIN2-C) is sufficient to rescue the levels of H3K14/23Ac of ein2-5 at the target
225 atment with a Ppara agonist is sufficient to rescue the loss of beige adipocytes caused by Lsd1 ablat
226 tation is specific to Deltalsr2; it does not rescue the maturation-deficient biofilms of a DeltagroEL
227 lleviating Mn toxicity as its expression can rescue the Mn-sensitive phenotype of the Arabidopsis mtp
228 formed cells; however, only EGFR was able to rescue the phenotype in cells lacking both RTKs indicati
229 nd an inability of ANKZF1 R585Q and E152K to rescue the phenotype of yeast deficient in Vms1, the yea
234 e cAMP analogue 8-bromo-cyclic AMP partially rescued the circadian phenotype in vivo We therefore pro
236 ed allele of AMD1 but not un-editable allele rescued the defects of amd1 in ascospore discharge.
238 (nonsense and frameshift) mutations in SAMD9 rescued the growth-restricting effects of mutant SAMD9 p
239 ally, systemic deletion of Cldn14 completely rescued the hypercalciuric and lower serum calcium pheno
240 gy of FXS as the GABABR agonist (R)-baclofen rescued the imbalances between excitatory and inhibitory
241 OD.Ncf1(m1J) bone marrow-derived macrophages rescued the inflammatory antiviral M1 macrophage respons
243 d in the brain, the AVM001b/2b neurons, also rescued the locomotion and motor defects, but not the de
244 to mitochondria isolated from DHA-fed mice, rescued the major losses in the mitochondrial phospholip
246 rticosterone-induced protein degradation and rescued the muscle atrophy and dysfunction in a Duchenne
247 ment with autophagy inducer tamoxifen, which rescued the NET formation defect in Mincle-/- neutrophil
249 AVPV reversed the prolonged cycle length and rescued the progesterone blockade LH surge, while RU486
250 c stimulated expression of IL-6 and IL-8 and rescued the tumor growth and migratory phenotypes of ova
254 mutant mice, while HK2 overexpression partly rescues the defects caused by suppression of FGF signall
255 n of recombinant CCL5 to C3aR-deficient mice rescues the defects in inflammatory cell recruitment and
256 zation with latrunculin in Rictor KO B cells rescues the defects of BCR signaling and B cell differen
257 iorates tauopathy in Tau-P301S mice but also rescues the deficits in synaptic integrity and plasticit
260 rexpression of PERK-K618A in primary neurons rescues the loss of dendritic outgrowth and number of sy
263 R593A mutant, whereas the addition of Gd(3+) rescues the mutant's sensitivity to GPCR-Gq/11-PLC-depen
264 f Cdc25A remedies the high mitotic index and rescues the premature differentiation of Mcph1-deficient
266 mory in AD transgenic mice and concomitantly rescues their hippocampal long-term potentiation deficit
267 educing SERCA activity in THADA mutant flies rescues their obesity, pinpointing SERCA as a key effect
273 that treatment with the c-src inhibitor PP2 rescued this effect, suggesting a role for GCs in promot
275 he motor cortex directly to the STN and that rescuing this loss alleviates Parkinsonian symptoms.
276 caused by in vitro inhibition of GCN5 can be rescued through RA-dependent mechanisms that require RAR
278 rehospital transfusion and time from MEDEVAC rescue to first transfusion, regardless of location (ie,
279 early stage in Flower-deficient CTLs and is rescued to wild-type level by reintroducing Flower or by
280 escue treatments and could be considered for rescue treatment for Plasmodium falciparum malaria.
282 me ACT shows similar efficacy as recommended rescue treatments and could be considered for rescue tre
284 a(2+) binding in either C2A or C2C failed to rescue two defects in PM lipid homeostasis observed in E
286 promised activity, which can be functionally rescued via blocking RNF8-MIWI interaction in spermatids
290 nce implicating altered proliferation in the rescue, we observe a significant increase in apoptotic c
292 therapy, efficient reovirus reverse genetics rescue will accelerate production of recombinant reoviru
298 tochondrial mass and Mfn2 levels, which were rescued with mitophagy blocker, bafilomycin, in FECD.
300 nd motor and sensory functions that could be rescued with therapeutic application of the heat shock p
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