1 s, but has never been tested with a rigorous
research design.
2 es and discuss ways they can be addressed in
research design.
3 he original reports according to the type of
research design.
4 psychopathology provide valuable focuses for
research design.
5 hould be considered a virtual requirement in
research design.
6 by ethical considerations that constrain the
research design.
7 ctices in social science and used a credible
research design.
8 this paper emerged from within the inductive
research design.
9 tive and theoretically appropriate for their
research design.
10 lausibility from different but complementary
research designs.
11 ulation level should be assessed with robust
research designs.
12 ol conditions that call for forward-thinking
research designs.
13 Trends suggest a growing maturity in the
research designs.
14 nd the remaining eight used a combination of
research designs.
15 llow-up genome scan, which used a consistent
research design across studies and examined the largest
16 4) How has
research design affected the results of studies of bupre
17 sex as a biologic variable be factored into
research design,
analyses, and reporting of vertebrate a
18 RESEARCH DESIGN AND A cannula was placed in the lateral
19 RESEARCH DESIGN AND A cross-sectional study of 1,066 men
20 RESEARCH DESIGN AND A nested case-control analysis was c
21 RESEARCH DESIGN AND A total of 11 intensively treated ty
22 RESEARCH DESIGN AND About 2% of LEW*1WR1 rats develop sp
23 RESEARCH DESIGN AND About 2% of LEW.1WR1 rats develop sp
24 RESEARCH DESIGN AND Ad*VEGF and Ad*Ang1 were intramyocar
25 RESEARCH DESIGN AND Adipocytes from intra-abdominal/peri
26 RESEARCH DESIGN AND Adult mice deficient in either p130
27 RESEARCH DESIGN AND Adult transgenic zebrafish were inje
28 RESEARCH DESIGN AND After congenic transfer of the NOD H
29 RESEARCH DESIGN AND After excluding subjects who reporte
30 RESEARCH DESIGN AND All studies were performed using per
31 RESEARCH DESIGN AND An expression plasmid of plasminogen
32 ic approaches and discuss factors related to
research design and analysis that can enhance the inform
33 RESEARCH DESIGN AND Angiogenesis (capillary density) and
34 RESEARCH DESIGN AND Apoptosis, albuminuria, ROS generati
35 tely require incorporation of both stringent
research design and assessment in the clinical context i
36 RESEARCH DESIGN AND At baseline, 301 type 2 diabetic par
37 RESEARCH DESIGN AND At baseline, 32 male adult cynomolgu
38 RESEARCH DESIGN AND beta-Cell mass, beta-cell proliferat
39 RESEARCH DESIGN AND Blood glucose, insulin, lipid measur
40 RESEARCH DESIGN AND Both human umbilical vein endothelia
41 RESEARCH DESIGN AND C57BL/6 Ldlr(-/-) mice were cross-br
42 RESEARCH DESIGN AND Cav1 knockout and wild-type C57BL/6
43 RESEARCH DESIGN AND Conscious 60-h fasted canines were s
44 Using a quasiexperimental
research design and daily data on EEC from 2007 to 2015,
45 forts are needed to coordinate and integrate
research design and data acquisition and interpretation
46 RESEARCH DESIGN AND Differentiated 3T3-L1, Simpson-Golab
47 RESEARCH DESIGN AND Dogs were fed a regular diet (lean)
48 RESEARCH DESIGN AND Effects of each therapy were tested
49 RESEARCH DESIGN AND Effects of high glucose on wound hea
50 RESEARCH DESIGN AND Eight subjects with risk-conferring
51 RESEARCH DESIGN AND ELVs released from adipose tissue we
52 d and opportunity for innovation in surgical
research design and evaluation.
53 RESEARCH DESIGN AND Experimental mice were pregnant fema
54 RESEARCH DESIGN AND Expression of RAGE, S100A8, S100A12,
55 These recommendations will improve
research design and facilitate study combinations, betwe
56 RESEARCH DESIGN AND Fifteen robustly associated type 2 d
57 RESEARCH DESIGN AND For fine-mapping, we sequenced WFS1
58 RESEARCH DESIGN AND For islet labeling, we adapted the F
59 RESEARCH DESIGN AND For this study, 22 type 1 diabetic s
60 RESEARCH DESIGN AND FOXO1 was tested in vivo by DNA bind
61 RESEARCH DESIGN AND From the Multi-Ethnic Study of Ather
62 rms of the health care enterprise combine in
research design and funding, as the latter bears the imp
63 RESEARCH DESIGN AND Gene-targeted mutations of either It
64 RESEARCH DESIGN AND Gene-trap techniques were used to ab
65 RESEARCH DESIGN AND Genotypic data from a genome-wide as
66 RESEARCH DESIGN AND Healthy human volunteers (n = 14) we
67 RESEARCH DESIGN AND Here, we examine the half-life of ad
68 RESEARCH DESIGN AND HIP rats were treated with sitaglipt
69 RESEARCH DESIGN AND ICR mice were food restricted by 50%
70 RESEARCH DESIGN AND In all, 5,290 single nucleotide poly
71 RESEARCH DESIGN AND In dietary-obese C57BL/6J mice, sodi
72 RESEARCH DESIGN AND In order to separate the transient n
73 RESEARCH DESIGN AND In this study, 10 obese diabetic and
74 RESEARCH DESIGN AND In this study, the anorectic effects
75 RESEARCH DESIGN AND In this study, we analyzed the pheno
76 RESEARCH DESIGN AND In vivo testing of mechanical and th
77 RESEARCH DESIGN AND Male C57BL/6 mice were fed a high-fa
78 RESEARCH DESIGN AND Male Grp78(+/-) mice and their wild-
79 RESEARCH DESIGN AND MCK-IL10 and wild-type mice were fed
80 Although there is variability in
research design and measured outcomes, evidence supports
81 RESEARCH DESIGN AND METHODS Seven studies of the STAMPEE
82 RESEARCH DESIGN AND METHODS Ten single nucleotide polymo
83 RESEARCH DESIGN AND METHODS- TLR4 gene expression and pr
84 RESEARCH DESIGN AND METHODS-Rats were cannulated and bil
85 Research design and methods: We established lymphoblasto
86 RESEARCH DESIGN AND METHODS; Genetic analysis of HLA-DRB
87 RESEARCH DESIGN AND METHODS; The glucoregulatory actions
88 RESEARCH DESIGN AND Mice (n = 10) were fed a control (10
89 RESEARCH DESIGN AND Mice deficient in the catalytic subu
90 RESEARCH DESIGN AND Mitochondrial matrix and membrane fr
91 RESEARCH DESIGN AND Mstn(Ln/Ln) mice were weaned onto a
92 RESEARCH DESIGN AND Muscle biopsies were obtained basall
93 RESEARCH DESIGN AND Mutations were directly sequenced, a
94 RESEARCH DESIGN AND Nephrin expression in human pancreas
95 RESEARCH DESIGN AND Nine subjects with the E23K genotype
96 RESEARCH DESIGN AND Nonsmokers (n = 18, aged 20 +/- 0.5
97 RESEARCH DESIGN AND Of 32,826 Nurses' Health Study parti
98 RESEARCH DESIGN AND Offspring of ethylnitrosurea-mutagen
99 RESEARCH DESIGN AND Participants from the Epidemiology o
100 RESEARCH DESIGN AND Participants were 1,399 women (39% b
101 RESEARCH DESIGN AND Perifusion analyses of isolated Munc
102 RESEARCH DESIGN AND Persistence of Tregs was assessed by
103 RESEARCH DESIGN AND Placental samples were analyzed usin
104 RESEARCH DESIGN AND Pregnant female Sprague-Dawley rats
105 RESEARCH DESIGN AND Rats exposed to recurrent insulin-in
106 RESEARCH DESIGN AND Rats were depleted of KCs by adminis
107 RESEARCH DESIGN AND Rats were fasted overnight.
108 RESEARCH DESIGN AND Relevant studies published before Ju
109 RESEARCH DESIGN AND Serum and adipose tissue biopsies we
110 RESEARCH DESIGN AND SIM1 was sequenced in 96 individuals
111 RESEARCH DESIGN AND Since 1993, the Diabetes Autoimmunit
112 stigators abstracted study details including
research design and sonographic imaging technique to det
113 Detailed
research design and statistical methods are presented in
114 RESEARCH DESIGN AND Steady-state kinetic parameters of A
115 RESEARCH DESIGN AND Sural nerve myelinated fiber density
116 RESEARCH DESIGN AND TCF7L2 expression in rodent islets a
117 RESEARCH DESIGN AND The CRR was evaluated in rats and mi
118 RESEARCH DESIGN AND The Diabetes Audit and Research in T
119 RESEARCH DESIGN AND The effect of preoptic area administ
120 RESEARCH DESIGN AND The INS gene was sequenced in 16 Fre
121 RESEARCH DESIGN AND The relationships of MetS or its com
122 RESEARCH DESIGN AND The Type 1 Diabetes Genetics Consort
123 RESEARCH DESIGN AND The Women's Antioxidant and Folic Ac
124 RESEARCH DESIGN AND Thirty-four G1/S regulatory proteins
125 RESEARCH DESIGN AND This was a population-based study (M
126 RESEARCH DESIGN AND Tissue gene and protein expression p
127 RESEARCH DESIGN AND To address this, we fed wild-type (W
128 RESEARCH DESIGN AND To distinguish neurons that mediate
129 RESEARCH DESIGN AND To evaluate the roles of AMPK and Ak
130 RESEARCH DESIGN AND To identify key metabolic pathways t
131 RESEARCH DESIGN AND To investigate the role of Isl-1 in
132 RESEARCH DESIGN AND Twelve young lean, 12 young obese, 1
133 RESEARCH DESIGN AND Twenty-two insulin-naive subjects wi
134 RESEARCH DESIGN AND Using data from an ongoing genome-wi
135 RESEARCH DESIGN AND Using data from an ongoing GWAS of p
136 RESEARCH DESIGN AND Using matrix-targeted photoactivatab
137 RESEARCH DESIGN AND Using miRNA microarrays, we profiled
138 RESEARCH DESIGN AND We analyzed T1-weighted magnetic res
139 RESEARCH DESIGN AND We analyzed the capacity of beta-cel
140 RESEARCH DESIGN AND We analyzed the morphology of the pa
141 RESEARCH DESIGN AND We applied multicolor flow cytometry
142 RESEARCH DESIGN AND We assessed adaptive beta-cell proli
143 RESEARCH DESIGN AND We assessed skeletal muscle microvas
144 RESEARCH DESIGN AND We compared the expression of VEGF-A
145 RESEARCH DESIGN AND We determined cytokine profiles in c
146 RESEARCH DESIGN AND We developed a protease-resistant du
147 RESEARCH DESIGN AND We developed an mfat-1 transgenic mo
148 RESEARCH DESIGN AND We evaluated 50 juvenile rats with D
149 RESEARCH DESIGN AND We examined the gene expression prof
150 RESEARCH DESIGN AND We examined this question in skeleta
151 RESEARCH DESIGN AND We first quantified insulin sensitiv
152 ntal influences) were controlled for by this
research design and we further adjusted for time-varying
153 RESEARCH DESIGN AND We generated a T-cell receptor (TCR)
154 RESEARCH DESIGN AND We generated IL-21R-deficient NOD mi
155 RESEARCH DESIGN AND We generated TgKO mice expressing SH
156 RESEARCH DESIGN AND We generated transgenic mice overexp
157 RESEARCH DESIGN AND We genotyped approximately 360,000 s
158 RESEARCH DESIGN AND We genotyped single-nucleotide polym
159 RESEARCH DESIGN AND We initially demonstrated that the M
160 RESEARCH DESIGN AND We investigated the effect of nutrit
161 RESEARCH DESIGN AND We investigated the molecular mechan
162 RESEARCH DESIGN AND We investigated the relations of ser
163 RESEARCH DESIGN AND We measured GDR, fasting glucose, an
164 RESEARCH DESIGN AND We observed that activation of AMPK
165 RESEARCH DESIGN AND We performed a 60-h endotoxemia prot
166 RESEARCH DESIGN AND We performed cross-sectional analyse
167 RESEARCH DESIGN AND We show that glucose, acting through
168 RESEARCH DESIGN AND We studied mammary tumor development
169 RESEARCH DESIGN AND We studied the ability of cellular a
170 RESEARCH DESIGN AND We tested whether iNKT-conditioned D
171 RESEARCH DESIGN AND We tested whether these variants are
172 RESEARCH DESIGN AND We used bacterial artificial chromos
173 RESEARCH DESIGN AND We used ELISPOT to characterize the
174 RESEARCH DESIGN AND We used individual level genotype da
175 RESEARCH DESIGN AND We used mice and islets deficient in
176 RESEARCH DESIGN AND We utilized in vivo (13)C nuclear ma
177 RESEARCH DESIGN AND Wild-type and Nur77 null mice were f
178 RESEARCH DESIGN AND With two parallel approaches-a fat b
179 The
research designs and analytic methods used to address cl
180 ties Questionnaire, in relation to different
research designs and clinical purposes.
181 Whereas the sophistication of
research designs and data analysis for the study of psyc
182 sion-making and have used multiple different
research designs and data collection methods to explore
183 gical variation, one that may provide better
research designs and inform public policy.
184 ating older adults with cancer, (2) leverage
research designs and infrastructure for generating evide
185 l numbers of patients and the use of varying
research designs and methods have limited research in th
186 We next review the
research designs and results obtained from animal studie
187 We focus first on the variety of
research designs and substantive issues to which SEM can
188 There was marked heterogeneity in
research designs and the assessment of sedentary time an
189 ent for psychotherapeutic effectiveness, (b)
research design,
and (c) treatment technique.
190 (FDA) regulations do not adequately address
research design,
and that emergency research fits within
191 elated statistics, which are found in recent
research designs,
and the identified variants often over
192 ing partly because interventional controlled
research designs are difficult to apply.
193 Research designs are needed that enable longitudinal inv
194 , the most common problems found in proposed
research designs are related to unwarranted assumptions
195 the importance of the prospective nature of
research design,
as well as the consequences of its aban
196 on records rather than unique patients); (2)
research design (
avoiding use in performing state-, hosp
197 mental health, which in turn have influenced
research-design changes in the field.
198 In implementing these prospective
research designs,
collaboration between researchers and
199 nd summarized according to key components of
research design concerning subject characteristics, ther
200 research results, and avoidable weakness in
research design,
conduct and analysis.
201 The natural experiment
research design controls for confounding variables, and
202 The co-twin control
research design controls for familial vulnerability and
203 problem, care orientation, conceptual bases,
research designs,
data analysis procedures, discussion o
204 In a previous article, the
research design,
details of the simulation protocol, and
205 In this article, the
research design,
details of the simulation protocol, inf
206 oL research from 1990-2010 by discipline and
research design (
e.g., descriptive, longitudinal, clinic
207 These concordant findings using 2 different
research designs emphasize the importance of reducing SH
208 The authors examined which, if any,
research design features and patient characteristics wou
209 ay provide guidance in clinical practice and
research design for sequencing and prioritizing advanced
210 To inform
research design,
implementation and dissemination, this
211 periments by replicating and extending their
research design in a large-scale field experiment.
212 data also underlines the importance of sound
research design in benchmarking and comparison of bioinf
213 nd summarized according to key components of
research design,
including lesion type, location, and ad
214 nce use in young people warrant high-quality
research design interventions to prevent or ameliorate t
215 ality of a study based solely on category of
research design is unscientific.
216 on included selection of area medical sites,
research design issues, comorbid conditions, alcohol abu
217 The most significant
research-design issues arose as a consequence of the lac
218 and data sharing in research through use of
research designs known to reduce inefficiencies, and fur
219 We conclude that recent advances in
research design may provide a transition that will bring
220 In particular, the focus is on issues of
research design,
measurements, mechanisms, potential eff
221 are reports, there was much heterogeneity in
research designs,
methods, study aims, and program targe
222 RESEARCH DESIGN/
METHODS AND RESULTS: Here, we identified
223 inical stroke is a desired goal, the current
research design of embolic protection devices focuses on
224 protocol that raises ethical questions about
research design or implementation for which there is no
225 However, from a clinical-management and
research-design perspective, patient self-reports can be
226 ppeared in peer-reviewed journals; had clear
research designs;
reported results for at least 20 male
227 ust be put in the context of the appropriate
research design selection.
228 ition research and community-based nutrition
research designs should be dictated by the local culture
229 using a complement of genetically sensitive
research designs suggest that smoking during pregnancy i
230 The Task Force examines evidence of various
research designs that addresses the key questions within
231 judgements could be a feature of evaluative
research designs that fail to accurately represent clini
232 Research designs that incorporate time have long been in
233 tions that produce eyeblink conditioning and
research designs that produce reinstatement in other for
234 In the hierarchy of
research designs,
the results of randomized, controlled
235 What is the optimal
research design to address whether current and future ex
236 nt progress and well-developed strategies in
research designed to accomplish flexible and stretchable
237 This article reviews progress in
research designed to accomplish these outcomes with esta
238 Research designed to ameliorate neurodevelopmental disor
239 The PGC has recently commenced a program of
research designed to deliver "actionable" findings-genom
240 y in existing studies highlight the need for
research designed to examine the stability, comorbidity,
241 This article reports on
research designed to identify a core set of healing skil
242 ely to share etiology, so results may inform
research designed to identify causes.
243 Research designed to identify the etiology of these prob
244 ll ultimately provide support for innovative
research designed to increase the availability of organs
245 The present brief review describes
research designed to link these general concepts by exam
246 gestive carcinomas (ADCs), highlight ongoing
research designed to optimize their therapeutic effectiv
247 Basic
research designed to overcome these obstacles is current
248 the last 30 years, there has been extensive
research designed to quantify the extent of oral bioavai
249 history orientation conducted field and lab
research designed to reveal how animals cope with the ci
250 t risk-benefit ratios are molecular-targeted
research designed to target away from known adverse sign
251 fication of this relationship has stimulated
research designed to understand how HDL metabolism is re
252 ritique by employing a variety of innovative
research designs to identify the causal effect of father
253 The
research design used geomorphological and palynological
254 hnologies for Advanced Genomics Analysis and
Research Design (
VANGARD), has developed a thorough exom
255 ignored the fact that Brosnan and de Waal's
research design was not capable of offering an unequivoc
256 g 3 studies using distinct but complementary
research designs were used: The Christchurch Health and
257 alternative to previously used epidemiologic
research designs when one is including localization in t
258 f the hospitalist model requires an adequate
research design,
which should include a precise definiti
259 so used cross-sectional and/or retrospective
research designs,
which led to researchers and clinician
260 cepted principles of scientific inquiry, the
research design will generate an appropriately phrased h