ライフサイエンスコーパス: resistant

1 stage BAFFR-Fc monotherapy were rendered T1D resistant.

2 se areas are the most aggressive and therapy resistant.

3 higher than the cutoff was deemed to be IMiD-resistant.

4 supports that Th17 cells are glucocorticoid resistant.

5 ,520 g ae ha(-1) and 16,813 plants confirmed resistant.

6 long latency, all tumors subsequently became resistant.

7 T OF EARLY ACTIVATION TAGGED 1 (TOE1)-miR172-resistant (35S::TOE1(R) ) and mutant (flowering locus T-

8 a significant tumor control in the rituximab-resistant A20-huCD20 tumors.

9 Osteoclasts were counted in tartrate-resistant acid phosphatase-stained sections.

10 tant enterococci, C difficile, and multidrug-resistant Acinetobacter.

11 that might be exploited to kill chemotherapy-resistant acute myeloid leukemia cells.

12 herapeutic applications against chemotherapy-resistant AML.Significance: These findings reveal a mito

13 These contained both vancomycin-resistant and -susceptible isolates.

14 ) of which are multidrug or extensively drug resistant and 38.2%, 51.9%, and 36.3% of which contain X

15 erally regarded as safe to consume, are bile-resistant and can plausibly be modified to produce a pan

16 world, and the increased number of multidrug-resistant and extremely drug-resistant strains is a sign

17 ifferential distribution between piperaquine-resistant and piperaquine-sensitive parasite lines.

18 rt actin filaments that are depolymerization resistant and sensitive to spectrin, adducin, and nuclea

19 t metastatic uveal melanoma is immunotherapy resistant and support the further investigation of immun

20 ) that were identified in a F2-cross of mice resistant and susceptible to infection with oral bacteri

21 terial pathogens are increasingly antibiotic resistant, and development of clinically effective antib

22 to target cells into heterogeneous, protease-resistant, antibody-inaccessible compartments.

23 athway in mediating pediatric severe therapy-resistant asthma (STRA).

24 RATIONALE: Severe, steroid-resistant asthma is the major unmet need in asthma thera

25 cription to synergistically kill even highly resistant B-ALL with diverse genetic backgrounds.

26 er understanding of how to manage antibiotic-resistant bacteria in the future.

27 rectly monitor the phenotypic switch in drug-resistant bacteria with temporal resolution.

28 alternative for the treatment of antibiotic-resistant bacterial infections.

29 e as adjunctive treatments against multidrug-resistant bacterial infections.

30 nthetic technologies and tested against drug-resistant bacterial strains.

31 We generate CDKi-resistant cancer cells and find that they have reduced p

32 ial short-term effects, but the emergence of resistant cancer cells is a major barrier to full cures.

33 ts for breast cancer fail to address therapy-resistant cancer stem-like cells that have been characte

34 is critical to address the emergence of drug-resistant cancers, but direct screening of all possible

35 th greater tumorigenic, metastatic, and drug-resistant capacity.

36 ellent inhibition of cell growth in the drug-resistant cell line H1975, without significantly affecti

37 imulate VSV replication and oncolysis in all resistant cell lines but only partially improve the susc

38 against the sensitive and Pgp overexpressing resistant cell lines was found to correlate directly wit

39 t cancer cells in a high mesenchymal therapy-resistant cell state are dependent on the lipid hydroper

40 rongest changes was also induction of IL6 in resistant cells and the expression was further increased

41 These results were confirmed in T-DM1-resistant cells from patient-derived HER2(+) samples.

42 RNA-mediated knockdown of isoform 2 in BRAFi resistant cells restored sensitivity to BRAFi compared w

43 and to restore the sensitivity of ribociclib-resistant cells to CDK4/6 inhibitors.

44 served increased susceptibility of cisplatin-resistant cells to NK cell cytotoxicity when neutralizin

45 Treatment of vemurafenib-resistant cells with the GLI1/GLI2 inhibitor Gant61 led

46 eeded to design future therapies that target resistant cells.

47 driving effects of Indomethacin in cisplatin-resistant cells.

48 vating (ADK-inactivating) alterations in all resistant clones and determined that ADK is required to

49 Finally, the resistant clones exhibit cross-resistance with oxaliplat

50 Antibiotic-resistant clones rapidly emerge mainly by acquisition of

51 s in the presence of 46B8, we isolated three resistant clones, all harbouring the same mutation (Ser3

52 nal evolution and the emergence of treatment-resistant clones.

53 ases (senPrP(Sc)) and to a lesser extent the resistant component (resPrP(Sc)).

54 Under insulin-resistant conditions such as obesity, pancreatic beta-ce

55 tive bacteria are expected to displace their resistant counterparts if resistance genes are costly.

56 ogression of prostate cancer to a castration-resistant (CRPC) state.

57 with 15-PGDH inhibitor + PGE2 or metabolism-resistant dimethyl-PGE2 resulted in preterm cervical rip

58 say, particularly for the diagnosis of azole-resistant disease.

59 ently, leading to subclonal heterogeneity of resistant disease.

60 h to May 2016 and 7 previously determined PB-resistant E. cloacae isolates from JMI Laboratories.

61 tributed to two potential causes: first, the resistant E11 populations possessed mutations that cause

62 ess flexible, target gatekeeper mutated drug-resistant EGFR-L858R/T790M, and covalently alkylate Cys7

63 ily member YES1 was amplified in osimertinib-resistant EGFR-mutant tumor cells, the effects of which

64 ly detect carbapenemase-producing carbapenem-resistant Enterobacteriaceae (CP-CRE) is an important el

65 Carbapenem-resistant Enterobacteriaceae (CRE) are a serious public

66 Carbapenem-resistant Enterobacteriaceae (CRE) are high-priority bac

67 Two collections of carbapenem-resistant Enterobacteriaceae (CRE) isolates were evaluat

68 Carbapenem-resistant Enterobacteriaceae have recently become an imp

69 Carbapenems resistant Enterobacteriaceae infections are increasing w

70 ccounted for almost half of the erythromycin resistant enterococci isolated from the wetland.

71 -resistant Staphylococcus aureus, vancomycin-resistant enterococci, C difficile, and multidrug-resist

72 ult in intestinal domination with vancomycin-resistant Enterococcus (VRE), leading to bloodstream inf

73 ncept, wild-type (ATCC 29212) and vancomycin-resistant Enterococcus cells were incubated at five diff

74 Vancomycin-resistant Enterococcus faecium (VREfm) is a leading caus

75 functional inactivation of sensitive but not resistant Env glycoproteins.

76 uced selective pressures favouring multidrug-resistant epidemic ribotypes and was associated with sub

77 er trial, children and adolescents with drug-resistant epilepsy who had undergone epilepsy surgery ha

78 ed in patients undergoing treatment for drug-resistant epilepsy.

79 Importantly, expression of degradation-resistant EXO1 resulted in hyper-resection, which attenu

80 arker for detecting the SfABCC2mut allele in resistant fall armyworm.

81 aracterized by the accumulation of apoptosis-resistant fibroblasts in the lung.

82 frequent seizures and a long history of drug-resistant focal epilepsy.

83 acement in the oocyte with a phosphorylation-resistant form of GNU, which promotes PNG-GNU complex fo

84 hibitors in CLL, in particular for ibrutinib-resistant forms of this disease.

85 ing tools are excellent at detecting BGCs or resistant genes in general, but provide little help in p

86 bidopsis has been used as a source for virus-resistant genes that derive from alterations in essentia

87 silencing of functional HvCERK1 gene in the resistant genotype CI9831, followed by gene expression a

88 Colonization by resistant gram-negative bacteria was significantly assoc

89 ssion and anxiety in traditionally treatment-resistant groups, including AN.

90 sed therapeutic to treat refractory and drug-resistant HCC.

91 ter pittii are a frequent cause of multidrug-resistant, healthcare-associated infections.

92 The prevalence of resistant HIV in Aruba has increased to alarming levels,

93 nt drug interactions and development of cART-resistant HIV.

94 Increasing antibiotic resistant hospital-acquired infections and limited new a

95 ity of protein markers to select for disease-resistant hygienic behavior in the European honey bee (A

96 th MTB dendritic cells (DCs) from putatively resistant individuals diagnosed with latent TB, and from

97 t care by providing faster detection of drug-resistant infecting strains and to help inform therapeut

98 high burden of community-onset antimicrobial-resistant infection among patients with acute febrile il

99 Multidrug-resistant infections were associated with recent anteced

100 predictors of community-onset antimicrobial-resistant infections.

101 47 (6%) had meticillin-resistant infections.

102 essential roles in the generation of steroid-resistant inflammation and AHR secondary to allergen- an

103 In an animal model of anti-TNF-resistant intestinal inflammation, genetic deletion or p

104 ate vaccine (PCV7) in 2000 reduced macrolide-resistant invasive pneumococcal disease (MR-IPD) due to

105 Following PCV13 introduction, dual macrolide-resistant IPD decreased 74.1% (incidence 0.32/100000 in

106 -carbapenemase-producing (non-CP) carbapenem-resistant isolates, and carbapenem-susceptible isolates.

107 own in the mutant cell line H1975 (erlotinib-resistant), it became sensitive to MET inhibition.

108 d when 9 patients with blaOXA-232 carbapenem-resistant K. pneumoniae infections were identified at a

109 Both imatinib-sensitive and imatinib-resistant Kit (Kit(mut)) become fully auto-phosphorylate

110 The rapid emergence of carbapenem-resistant Klebsiella pneumoniae (CRKP) represents a majo

111 h would explain the widespread occurrence of resistant larvae in Bt fields across the main area of ma

112 ontacting solution from the metal, a protein resistant layer, which prevents nonspecific interactions

113 ion of the wildtype allele of wag31 in APYS1-resistant M. tuberculosis was dominant and restored susc

114 reat promise as high load bearing and impact-resistant materials due to a unique layered deformation

115 ly ill patients to infection with multi-drug resistant (MDR) bacteria are determined by many complex

116 CRISPR-Cas systems are absent from multidrug-resistant (MDR) Enterococcus faecalis, which only posses

117 e used as extracellular electron shuttles by resistant microbes.

118 antitubercular drug used to combat multidrug-resistant Mtb strains.

119 me tumor cells to interconnect to one large, resistant multicellular network.

120 d Dhar et al. (in press), the combination of resistant mutant generation, whole genome sequencing and

121 Co-expression of cathepsin B and cathepsin B-resistant mutant LFABP in McA-RH7777 cells resulted in a

122 For antibacterial compounds, generation of resistant mutants followed by whole genome sequencing ha

123 Phage-resistant mutants had impaired infectivity.

124 Ceftazidime/inhibitor resistant mutants hyperproduce L1, but retain aztreonam/

125 We identified heavy smokers that were resistant (n = 65) or susceptible (n = 64) to emphysema

126 (n=9); or (2) treatment response: treatment resistant (n=5) or treatment responsive (n=4).

127 y expressed genes (DEGs) was obtained in the resistant (Namikonga) variety at 2 days after grafting (

128 their correlation with renitence and damage-resistant nature, we termed these structures "renitence

129 Steroid-resistant nephrotic syndrome (SRNS), a heterogeneous dis

130 Steroid-resistant nephrotic syndrome is characterized by podocyt

131 R)-active, porous, conductive, and corrosion-resistant nitride Ni3 FeN is used as a support for oxyge

132 n in multiple EGFR tyrosine kinase inhibitor-resistant non-small-cell lung cancer models.

133 ty in patients with progressive or treatment-resistant NSCLC, providing a rationale for further studi

134 n 46.7% (7/15) of the patients with EGFR-TKI-resistant NSCLC, suggesting that the NGS-based ctDNA ass

135 implicated in the transmission of multidrug-resistant organisms (MDRO).

136 infections including those due to multidrug-resistant organisms (MDROs).

137 Although C auris is inherently multidrug resistant, other strains typically develop resistance th

138 ent-derived platinum-sensitive and platinum- resistant ovarian cancer cells and ovarian cancer stem c

139 Treatment of mice harboring platinum-resistant ovarian tumor xenografts with pHLIP-PNA constr

140 ctivity of colistin in vivo against colistin-resistant P. aeruginosa.

141 and shRNA-mediated HOTAIR knockdown in TRAIL-resistant PANC-1 cells sensitized them to TRAIL-induced

142 genome-wide accumulation of mutations in the resistant parasites, in addition to variations in DNA co

143 rease in the load of antimony-sensitive and -resistant parasites, thus confirming that Wnt5a signalin

144 aria due to their activity against multidrug resistant parasites.

145 testing (AFST) of the potentially multidrug-resistant pathogen Candida glabrata against anidulafungi

146 biotics and with the emergence of vancomycin-resistant pathogens (VRSA and VRE), the studies pave the

147 a-patient dissemination of highly antibiotic-resistant pathogens.

148 ions caused by this most intractable of drug resistant pathogens.

149 from infection and suppress the emergence of resistant pathogens.

150 facilities (SNFs), and at various risks for resistant pathogens.

151 The downstream mediators of insulin-resistant pathophysiology remain unclear.

152 ed in resistant tumors, as well as in HDM201-resistant patient-derived tumor xenografts.

153 dvanced EGFR-TKI-naive NSCLC and 15 EGFR-TKI-resistant patients to identify somatic SNVs, small indel

154 In obese, insulin-resistant patients with nonalcoholic fatty liver disease

155 % of drug-sensitive patients and 83% of drug-resistant patients, it is necessary to develop a better

156 D, and has particular relevance for anti-TNF-resistant patients.

157 only partially improve the susceptibility of resistant PDACs to VSV.

158 ignin biosynthesis were also up-regulated in resistant plants and electrophoretic mobility shift assa

159 osate sensitive A tuberculatus In glyphosate-resistant plants, a cluster of EPSPS genes on the perice

160 with resistance such that the most and least resistant populations exhibit lower anther-stigma separa

161 iotic resistance, and particularly multidrug-resistant profiles, is certainly of paramount relevance,

162 tate cancer either in the form of castration-resistant prostate cancer (CRPC) or transdifferentiated

163 rpose In patients with metastatic castration-resistant prostate cancer (mCRPC), overall survival (OS)

164 tment in patients with metastatic castration-resistant prostate cancer (mCRPC).

165 r (R)-9bMS-sensitized naive and enzalutamide-resistant prostate cancer cells and reduced AR and AR-V7

166 y are an unmet need in metastatic castration-resistant prostate cancer clinical research and practice

167 ell lines and cfDNA obtained from castration-resistant prostate cancer patients.

168 al benefit in men with metastatic castration-resistant prostate cancer with the addition of custirsen

169 ith chemotherapy-naive metastatic castration-resistant prostate cancer without visceral metastases.

170 erapy and in approximately 30% of castration-resistant prostate cancer.

171 romodomain as a strategy to treat castration-resistant prostate cancer.

172 apeutic efficacy of paclitaxel in paclitaxel-resistant prostate cancer.

173 PC tumors compared to primary and castration-resistant prostate cancers, and its expression is negati

174 NA is periodically anchored to an extraction-resistant protein structure, via matrix attachment regio

175 ning both proteinase K (PK)-sensitive and PK-resistant PrP(Sc) and samples containing only the PK-res

176 t PrP(Sc) and samples containing only the PK-resistant PrP(Sc).

177 nosa is an opportunistic and frequently drug-resistant pulmonary pathogen especially in cystic fibros

178 Common resistant regions to digestion were identified, revealin

179 Nifedipine-resistant RRP exocytosis was poorly affected by 5 mm int

180 ulates the cost-effectiveness of methicillin-resistant S aureus prevention strategies and recommends

181 xtended-spectrum beta-lactamase, methicillin-resistant S. aureus, and carbapenem-resistant strains wa

182 shifts between antimicrobial susceptible and resistant Salmonella.

183 roaches to improve treatment of chemotherapy-resistant SCCs.

184 severe, presenting in infancy with pharmaco-resistant seizures; are often accompanied by debilitatin

185 However, other macrolide-resistant serotypes (eg, 15A and 35B) not currently repr

186 vo genome and plastome assemblies for a wilt-resistant South African accession of Mentha longifolia (

187 Two types of resistant soybean (Glycine max (L.) Merr.) sources are w

188 kely decline on most reefs, especially where resistant species like S. siderea are not already domina

189 etracycline-, erythromycin-, and clindamycin-resistant ST first identified in Minnesota, which is con

190 pervirulent, community-acquired, methicillin-resistant Staphylococcus aureus (CA-MRSA) with specific

191 The rate of infection by methicillin-resistant Staphylococcus aureus (MRSA) has declined over

192 the era of community-associated methicillin-resistant Staphylococcus aureus (MRSA) is unclear.

193 sequencing epidemic lineages of methicillin-resistant Staphylococcus aureus (MRSA) over sensitive is

194 Meticillin-resistant Staphylococcus aureus (MRSA) was first reporte

195 rent binding domains specific to methicillin-resistant Staphylococcus aureus (MRSA).

196 tent antibiotic activity against methicillin-resistant Staphylococcus aureus (MRSA).

197 Livestock-associated methicillin-resistant Staphylococcus aureus clonal complex 398 (LA-M

198 acquisition and infection due to meticillin-resistant Staphylococcus aureus, vancomycin-resistant en

199 hcare-associated infections like methicillin-resistant Staphylococcus aureus.

200 chment of slowly digestible starch (SDS) and resistant starch (RS) content in pea bread were investig

201 sponge cakes exhibited an enhancement of the resistant starch and dietary fiber content with the repl

202 melo incorporated bread had higher levels of resistant starch fractions (3.87-10.96%) with low predic

203 ave potential both as a starch and also as a resistant starch source.

204 transient transcriptional state to a stably resistant state.

205 polymorphism previously identified in a PZA resistant strain does not confer PZA resistance when rec

206 possess potent activity against a multidrug resistant strain of P. falciparum and arrest parasites a

207 Antibody-resistant strains arising through further gene deletion

208 er of multidrug-resistant and extremely drug-resistant strains is a significant reason for concern.

209 ampicillin and tetracycline on sensitive and resistant strains of E.coli, as well as effects of ampho

210 nsmission of cefixime-sensitive and cefixime-resistant strains of Neisseria gonorrhoeae in MSM in Eng

211 hicillin-resistant S. aureus, and carbapenem-resistant strains was also observed.

212 obacterium tuberculosis, including multidrug-resistant strains, and some species of nontuberculous my

213 r, they maintained good activity also toward resistant strains, and they were selective over other ba

214 depletion of 1 other putative metabolite in resistant strains.

215 unbiased approach based on RNA sequencing of resistant subclones, to discover the molecular mechanism

216 antly in Kenya and Ethiopia, whereas the MAb-resistant subgenotype D4.2 MeVs were isolated predominan

217 ism that distinguishes CoB-sensitive and CoB-resistant T cell populations to reduce the risk of CoBRR

218 s significant role for the treatment of drug-resistant TNBC.

219 Moreover, Pml(-/-) animals are resistant to acetaminophen hepatotoxicity or fasting-ind

220 The tube surface is resistant to adhesion of activated platelets unlike plan

221 sting that a fraction of virus particles are resistant to antibody neutralization despite high antibo

222 ial infection, POP2 transgenic mice are more resistant to bacterial infection than wild-type mice.

223 adhesion (>3-fold), the epithelium remained resistant to bacterial penetration.

224 sults suggest that the microbiome is largely resistant to changes during sleep restriction.

225 LSCs, which are resistant to chemotherapy and serve as reservoirs for re

226 ession of USP13 renders ovarian cancer cells resistant to chemotherapy.

227 Leukaemia cells that are resistant to conventional therapies are thought to resid

228 patients with inflammatory arthritis remain resistant to current therapies, and even effective anti-

229 In accord with these results, EXO1 became resistant to degradation when its SQ motifs required for

230 the kidney, liver, and adipose tissues were resistant to developing high-fat diet-induced obesity an

231 Nevertheless, the replisome is highly resistant to dilution in the absence of Pol III* in solu

232 fiber low-threshold mechanoreceptor neurons) resistant to direct and trans-synaptic infection from th

233 C57BL/6 mice deficient in GM-CSF are resistant to EAE induced by immunization with myelin oli

234 lity to bacterial infection and were largely resistant to endotoxin-induced septic shock.

235 sal keratins of the skin epithelium are very resistant to evidence-based structural analysis because

236 ma driven by a mutant SMO that is inherently resistant to existing SMO inhibitors, prolonging the sur

237 ve learning of incentive cues that is highly resistant to extinction.

238 we found that stream sticklebacks were more resistant to Gyrodactylus and had different gene express

239 r specific Ant2 knockout mice are leaner and resistant to hepatic steatosis, obesity and insulin resi

240 ce transfused with these red blood cells are resistant to highly lethal doses of BoNT/A.

241 ice lacking Sts expression are significantly resistant to infection by the live vaccine strain (LVS)

242 CD163 knockout (KO) pigs are resistant to infection with genotype 2 (type 2) porcine

243 tors of TLR4 in modern wheat and were highly resistant to intestinal proteolysis.

244 which when deleted caused animals to be more resistant to IR, whereas cel-mir-237 overexpressing stra

245 tal pathways, bacteria may not easily become resistant to killer cell attack.

246 ed with the peptide at 0.1 nM are completely resistant to killing by C. albicans The peptide also pro

247 nd chemotaxis, and TIPE2-deficient mice were resistant to leukocyte-mediated neural inflammation.

248 These surface electrons are exceptionally resistant to localization by non-magnetic disorder, and

249 Chromatinized genomic DNA is resistant to MjAgo degradation, and recombinant histones

250 Bcc pathogens are intrinsically resistant to multiple antibiotics, including beta-lactam

251 hical distribution and many producer strains resistant to multiple other antibiotics.

252 Rag2(-/-)gammac(-/-) mice are as resistant to Mycobacterium avium as Rag2(-/-) mice, wher

253 GSB were resistant to oxygen and showed a low affinity to sulfide

254 albicans infection produces elongated hyphae resistant to phagocytic clearance compelling alternative

255 andemic O1 Vibrio cholerae biotype El Tor is resistant to polymyxins, whereas a previous pandemic str

256 Conversely, among patients who were resistant to R-CHOP, basal DLBCL mutations did not disap

257 unaffected by more salient loss signals and resistant to response cost increases.

258 ivation, mTORC1 is constitutively active and resistant to serum and amino acid starvation.

259 of SMPD1 in human NSCLC cells rendered them resistant to serum starvation-induced apoptosis.

260 taphylococcus aureus or staph, because it is resistant to some commonly used antibiotics.

261 The resultant tumor-free mice were resistant to subsequent challenge with CT26, indicating

262 igh Arctic is generally considered to remain resistant to such shrub expansion in the next decades.

263 s involves cell-to-cell transmission that is resistant to tetherin but that virion dissemination via

264 Grik4-cre;Hdac1(fl/f) mice, which were more resistant to the excitotoxic damage induced by intravent

265 PIK3CA(H1047R) transgenic mammary tumors are resistant to the HER2 antibodies trastuzumab and pertuzu

266 ths, Tomelo, a non-transgenic tomato variety resistant to the powdery mildew fungal pathogen using th

267 ing or had no experience of re-use were most resistant to the re-use of catheters.

268 splastic syndromes (MDS) either sensitive or resistant to their respective therapy.

269 is a highly lethal and disseminating cancer resistant to therapy, including checkpoint immunotherapi

270 frontline treatment and many patients become resistant to these agents early in the course of their d

271 nd reveals characteristics of subpopulations resistant to this treatment.Significance: Illustrating t

272 Flowers silenced in NaJAZi are more resistant to tobacco budworm attack, a florivore.

273 d and anxiety disorders that were previously resistant to treatment.

274 However, they are resistant to tumorigenesis, and most normal cells isolat

275 ive against most PDAC cells, some are highly resistant to VSV, and the mechanisms are still unclear.

276 IFNs (IFNlambda1 and IFNlambda2) and become resistant to ZIKV infection.

277 The broad spectrum of eIF4F-resistant translatomes is incompatible with cap-independ

278 Xpert MTB/RIF (Xpert) detects rifampicin-resistant tuberculosis (RR-tuberculosis), enabling physi

279 Although patients with isoniazid-resistant tuberculosis had a high cure rate, the cases o

280 primary analysis, the incidence of multidrug-resistant tuberculosis in 2024 would be 3.3 (95% uncerta

281 ve supported programmatic management of drug-resistant tuberculosis in 90 countries.

282 Although isoniazid-resistant tuberculosis is more common than multidrug-res

283 s of 20 downstream cases of extensively drug-resistant tuberculosis with almost identical sequencing

284 t tuberculosis is more common than multidrug-resistant tuberculosis, it has been much less studied.

285 sector contributed 87% of acquired multidrug-resistant tuberculosis, related to irregular adherence;

286 Organization to treat leprosy and multi-drug-resistant tuberculosis.

287 2D culture where MDA-MB-231 attained a drug-resistant tumor-initiating phenotype indicated by increa

288 In this study, the authors show that resistant tumors display high Akt activation and that a

289 BET bromodomain inhibition resensitizes drug-resistant tumors to Enz by selectively impairing the GR

290 and MDM4 protein expression was confirmed in resistant tumors, as well as in HDM201-resistant patient

291 emotaxis and homeostasis reappeared in BRAFi-resistant tumors.

292 ific resistance mechanisms to sensitize ICBT-resistant tumors.

293 1 unique resistance alleles across 1934 drug-resistant tumours.

294 beta-synuclein (betaS) is essentially fibril-resistant under cytoplasmic physiological conditions.

295 sispecies and the pre-existence of some drug-resistant variants in the liver, which are not necessari

296 treated subjects experienced infection with resistant virus while in the isolation facility, 3 (3%)

297 tent plastic potential that durably improves resistant visual attention deficits after brain injury.

298 Evaluation of CRPC cell lines identified resistant vs sensitive in vitro models, and revealed tha

299 splayed M2 polarization, whereas bevacizumab-resistant xenografts transduced to upregulate MIF exhibi

300 olyamide was active against two enzalutamide-resistant xenografts with minimal toxicity.