ライフサイエンスコーパス: resolving power

1 y being improved, especially in terms of the resolving power.

2 out encountering the field-dependent loss of resolving power.

3 0 ion mobility resolving power and 2000 mass resolving power.

4 er magnetic fields are used to increase mass resolving power.

5 cy encoded in the analyte gradient increases resolving power.

6 the IMS drift tube and reduction in the IMS resolving power.

7 ted to <1% in order to maintain instrumental resolving power.

8 significantly reduced, resulting in improved resolving power.

9 nized, and detected in the FTMS with >70 000 resolving power.

10 apparent resolution matches the instrument's resolving power.

11 er parameters with regard to sensitivity and resolving power.

12 s system dramatically increase in number and resolving power.

13 e unfolding mechanism that provides a robust resolving power.

14 e-of-flight (TOF) instrument with lower mass resolving power.

15 rom information misinterpretation due to low resolving power.

16 y swept on signal-to-noise ratios (SNRs) and resolving power.

17 ra measured with high mass accuracy and high resolving power.

18 ignments must account for the peak shape and resolving power.

19 nces, because of limitations in the spectral resolving power.

20 same nominal mass and overlapped at previous resolving powers.

21 pic resolution up to m/z-value 12,000 (e.g., resolving power 39,000 at m/z-value 12,000) providing mo

22 S and TWIMS, with DTIMS demonstrating higher resolving power (70-80) than TWIMS (30-40).

23 In addition to mass resolving power, absorption mode offers higher mass accu

24 Besides the excellent resolving power afforded by both CIEF and CZE separation

25 It was confirmed by comparing the resolving powers after and before resolution recovery.

26 cing the run time and, thus, by reducing the resolving power along the first dimension separation.

27 tests have shown obtaining 100 ion mobility resolving power and 2000 mass resolving power.

28 attributable, in part, to a loss in temporal resolving power and ability to adjust dynamic range.

29 sma lysozyme was conducted by utilizing high resolving power and an EIC window fitting to the protein

30 Phase correction further improves the resolving power and average absolute deviation by 1.3-fo

31 he workflow and taking advantage of the high resolving power and dynamic range of a Fourier transform

32 The increases in resolving power and ensuing peak resolution are especial

33 in commercial mass spectrometers with higher resolving power and faster scanning capabilities have ex

34 tching method maintained the chromatographic resolving power and high sensitivity of the LC-MS-MS ass

35 However, both resolving power and ion transmission showed a dependence

36 required for spectral acquisition of a given resolving power and mass accuracy decreases linearly wit

37 A scan rate of >1 Hz is possible with resolving power and mass accuracy equivalent to direct i

38 Nevertheless, the ultrahigh mass resolving power and mass accuracy of FT-ICR MS enable de

39 the unique advantage of delivering high mass resolving power and mass accuracy simultaneously, making

40 necessary to use instrumentation with a high resolving power and mass accuracy when studying complex

41 n two MS/MS experiments while characteristic resolving power and mass measurement accuracies were mai

42 e method is demonstrated to have significant resolving power and peak capacities far in excess of wha

43 arkers with higher F(ST) values have greater resolving power and produce more consistent genetic dist

44 e PSDVB-based stationary phases provide good resolving power and reproducibility and are applicable t

45 the fractionator was modified to improve the resolving power and reproducibility of separation.

46 exchange separations, while having excellent resolving power and robustness, are product specific and

47 vements in IMS-MS instrumentation, e.g., IMS resolving power and sensitivity, are highly desirable.

48 rture grid to anode distance on the observed resolving power and sensitivity.

49 eversed phase gradient, providing additional resolving power and significantly improved desorption of

50 imaging has recently led to a revolution in resolving power and tissue contrast in biomedical imagin

51 guities, while taking into consideration the resolving power (and its decay) of different mass analyz

52 erizing suitable sample flow rates, temporal resolving power, and analyte concentrations.

53 it of detection (LOD), linear dynamic range, resolving power, and collision cross section (Omega) are

54 specific optimum voltage, gate pulse width, resolving power, and now CRM for each ion.

55 the centimeter scale, with high performance, resolving power approaching 100 or higher.

56 Resolving power approaching the theoretical limit was ac

57 within humic and fulvic acid mixtures (mass resolving power approximately 80000 at 300 m/z).

58 In other words, the achieved resolving powers are 4 times higher than those provided

59 tures resulted in a leveling of the measured resolving power as a function of pressure.

60 hile a greater frequency swept increases the resolving power at the expense of SNR.

61 Both geometries provide IMS resolving powers at the theoretical limit (R ~ 58), show

62 as utilized, TWIMS was found to operate at a resolving power between 40 and 50, confirming the previo

63 At mass resolving powers between 60,000 (high mass) and 120,000

64 aise the mobilities of all ions and thus the resolving power beyond that previously feasible, while a

65 a nonclassical imaging mechanism with super-resolving power beyond the Rayleigh limit.

66 ansfer path for solutes are less affected in resolving power by increases in mobile-phase velocity th

67 ventional light microscopy is limited in its resolving power by the Rayleigh limit to length scales o

68 Estimates of spatial resolving power calculated using cone peak densities are

69 Simulation and theoretical resolving power calculations were made to validate the e

70 However, a gain in mass resolving power can also be realized by phase correction

71 a drift length of 9242.03 cm) values of the resolving power can exceed 300 with a maximum resolving

72 distinguishes C. jejuni from C. coli, has a resolving power comparable to that of multilocus sequenc

73 of trace enantiomeric impurities), and high resolving power (comparable to capillary electrophoresis

74 romosome-based FISH mapping shows a superior resolving power compared to the somatic metaphase chromo

75 the field of microscopy by providing higher resolving power compared to their optical counterpart.

76 irmed that in addition to the improvement on resolving power, compared to the conventional magnitude-

77 there exists an optimum voltage above which resolving power decreases.

78 ference in the gas-phase CCS and a CCS-based resolving power definition (CCS/DeltaCCS).

79 Interestingly, the apparent resolving power depends strongly on the identity of the

80 At high pressures, however, resolving power did not increase as much as theory predi

81 ce microscopy has made a quantum leap in its resolving power due, in large part, to advancements over

82 MS) system has been created that maintains a resolving power efficiency of 80% regardless of the pres

83 ne IMS ranged from 42 to 54, yielding an IMS resolving power efficiency, defined as R m/ R c x 100%,

84 ble without tilting the specimen.Beyond high resolving power, electron microscopy can be used to stud

85 This high mass resolving power ensures that closely spaced peaks at the

86 A "conditional" resolving power equation is introduced that can be used

87 Thus, the experimental enhancement in mass resolving power (factor of 1.43 +/- 0.09) for isotopical

88 tly upon genomic coverage and the consequent resolving power for discerning somatic mutations.

89 To date, this technology affords limited resolving power for discerning subtle pathological chang

90 ce mass spectrometry offers the highest mass resolving power for molecular imaging experiments.

91 The maximal measured resolving power for our small, ambient-pressure stand-al

92 es the FAIMS separation capability, with the resolving power for peptides and peak capacity for prote

93 ular metabolites within 20 min and excellent resolving power for polar molecules including many isoba

94 ant analyte concentration and extremely high resolving power for separated protein mixtures.

95 increase in MS acquisition rate per unit of resolving power for signal detection periods typically e

96 Detection limits determined at the optimal resolving power for the environmental contaminants range

97 The estimated resolving power for the ESI-HPIMS used in this study was

98 ht) intersect, this method affords excellent resolving power for the functional analysis of neural ci

99 In conclusion, the most effective mass resolving powers for profiling analyses of metabolite ri

100 can be used to quickly approximate realistic resolving powers for specific instrumental operating par

101 Also, the resolving power gains are often at the expense of speed,

102 e mass composition assignments with spectral resolving power greater than 8000.

103 ixtures comprising up to 75% He have enabled resolving power >100 that permits separation of numerous

104 ranslates to an increase in theoretical mass resolving power (>10000 full width half-maximum for the

105 e-selected ion monitoring (H-SIM) mode (mass resolving power, >12,500 fwhm) was proposed monitoring t

106 etic focusing-based separations include high resolving power, high concentration and narrow analyte b

107 These spectra yield resolving power improvement factors approaching the maxi

108 Overall, we observe that instrumental resolving power improves with increasing cycle numbers;

109 An increase in the resolving power in 2D NMR spectra is obtained by collaps

110 h increasing cycle numbers; at 100 cycles, a resolving power in excess of 1000 can be achieved.

111 y the effect of space charge on ion loss and resolving power in IMS systems.

112 addressed the necessity of instrumental mass resolving power in terms of clinical diagnosis and progn

113 14,271 cells/mm(2), upper limits of spatial resolving power in the temporal area ranged from 25 to 2

114 Resolving powers in excess of 300 are obtainable with th

115 Although diffusion theory predicts that IMS resolving power increases with the square root of the vo

116 f ion residence time in FAIMS, which affects resolving power independently of ion desolvation after t

117 richia coli, most have drawbacks in terms of resolving power, interpretability, or scalability.

118 For the modified instrument, the mass resolving power is approximately 8000 for a wide m/z ran

119 The practical resolving power is determined by the signal-to-noise rat

120 eloped and tested a TM-IMS, and the measured resolving power is R = 55.

121 A chromatography existing concept of resolving power is used to differentiate between peak re

122 After the separation axis (and corresponding resolving power) is converted to cross section space, it

123 The ultrahigh mass resolving power (m/delta m50% >200,000) and mass accurac

124 With sufficiently high mass resolving power (m/Deltam(50%) approximately 400,000, in

125 lotron resonance broadband mass spectrometry resolving power (m/deltam50% > 350,000 for 200 < m/z < 1

126 spholipids at sub-ppm mass accuracy and high resolving power (m/Deltam50% = 200 000 at m/z 400) at 1

127 broadband FTICR mass spectrometry at a mass resolving power, m/delta m50% > or = 400,000 has achieve

128 versus S (9.5 mDa), requiring a minimum mass resolving power ((m2 - m1)/ml) of 118,000 (C terminal am

129 pectrometry, this translates to greater mass resolving power, mass accuracy, mass-to-charge range, ef

130 e mass spectrometry (FTICR MS) delivers high resolving power, mass measurement accuracy, and the capa

131 classes of biomolecules, not requiring high-resolving power MS for quantitation and being relatively

132 ompatibility of IEF-SPLC processing and high resolving-power MS analysis with results showing ~7.0 fe

133 issociation (ExD) tandem MS analysis and the resolving power needed to resolve isobaric fragments.

134 n order to predict the required ion mobility resolving power needed to separate the various isomer cl

135 a function of pressure, with higher optimal resolving powers obtained at higher voltages, as predict

136 illary LC-FTICR analysis provided a combined resolving power of > 6 x 10(7) components.

137 obility separations benchmark at a CCS-based resolving power of >300 that is sufficient to differenti

138 aluated in this study, a uniform field-based resolving power of 100 was predicted to be sufficient to

139 s spectrometer source, and the expected mass resolving power of 100000 to 400000 is achieved.

140 MS cell of 10.7 cm length has demonstrated a resolving power of 102 when operated at 2.5 atm.

141 Spectra measured here have an average resolving power of 12 000.

142 ass measurement accuracy of 1 ppm and a mass resolving power of 120000 in analysis of protein digests

143 -4342 in the 1000 to 1187 angstrom band at a resolving power of 15,000.

144 des and hypothesis testing indicate that the resolving power of 18S rDNA sequences is limited for exa

145 for the first time, a fair comparison of the resolving power of 1D- and 2DLC under realistic conditio

146 ods should be able to effectively extend the resolving power of 2-D separation methods.

147 28 cm long OMS instrument is shown to have a resolving power of 20 and is capable of attomole detecti

148 uracy typically less than 300 ppb rms, and a resolving power of 200,000 (m/Delta m50% at m/z 400) is

149 -resolution ion mobility spectrometer with a resolving power of 250 and an UV ionization source enabl

150 egy for separating such samples, because the resolving power of 2D-LC is far superior to that of trad

151 In intact protein analysis, the average resolving power of 340,000 across the baseline-resolved

152 he shift frequency to yield a device limited resolving power of 400 (m/Deltam).

153 a tandem MS experiments with an average mass resolving power of 4450 for product ion analysis, and pr

154 tion with a routinely used mass spectrometer resolving power of 5000; and (d) recoveries of the five

155 generated was performed with an average mass resolving power of 6200 and a mass accuracy of up to 10

156 ength), we estimated upper limits of spatial resolving power of 7 cycles/deg (temporal area), 6.6 cyc

157 tube with a tritium ionization source and a resolving power of 70.

158 ength), we estimated upper limits of spatial resolving power of 8 cycles/deg (temporal area, 1,800 ce

159 An actual resolving power of 80 was achieved for two doubly charge

160 than 26,000 assigned peaks, Fourier-limited resolving power of 800,000 at m/z 500 (6.6 s transient d

161 A spatial resolving power of 9.8 mum, well below the optical limit

162 The addition of high resolution TIMS (resolving power of 90-220) to ultrahigh resolution FT-IC

163 e 3D convex surfaces with at least twice the resolving power of a conventional 2D diffraction grating

164 lotting and combines, in two dimensions, the resolving power of a denaturing protein gel with that of

165 The ability to tune the resolving power of a mobility-based separation by varyin

166 The resolving power of a PEDOT-PSS detector array was compar

167 ely 1% of the previously needed time, with a resolving power of about half that for "macroscopic" uni

168 The combination of high resolving power of an FTICR analyzer and matrix subtract

169 r 2 mum for biomolecules) with the high mass-resolving power of an Orbitrap (>240,000 at m/z 200).

170 n upper m/z-limit of at least 300 and a mass resolving power of approximately 1000.

171 lotron resonance mass spectrometry at a mass resolving power of approximately 3 300 000.

172 lotron resonance mass spectrum (average mass resolving power of approximately 350,000 from 225 to 100

173 esolving power can exceed 300 with a maximum resolving power of approximately 400.

174 are typically measured to within 2 ppm at a resolving power of approximately 60 000.

175 f coherent transfer functions, the underling resolving power of axially structured geometries is inve

176 ging ligands are discernible due to the high resolving power of CE.

177 In addition, the resolving power of CEX is often considered to be limited

178 The ultrahigh resolving power of CITP/CZE is evidenced by the large nu

179 he second separation dimension for increased resolving power of complex peptide mixtures.

180 sely spaced tags is possible due to the high resolving power of current day mass spectrometers.

181 reveals an important discrepancy between the resolving power of current forensic analytical chemistry

182 t a microfluidic device that can enhance the resolving power of CZE analysis by generating a pressure

183 Single-pixel X-ray detectors now have a resolving power of DeltaE < 5 eV for single 6-keV photon

184 The resolving power of differential ion mobility spectrometr

185 Combining the high resolving power of Fourier transform mass spectrometry w

186 The high mass resolving power of FTICR MS was exploited to identify TP

187 With the high resolving power of FTICR MS, it was possible to differen

188 The superior resolving power of HIC made it possible to prepare highl

189 omb, or 'astro-comb', is well matched to the resolving power of high-resolution astrophysical spectro

190 ed expressions that predict the ion loss and resolving power of IMS systems as a function of input ch

191 drift tube has the potential to increase the resolving power of IMS, but operation at low temperature

192 s paper reports a protocol that improves the resolving power of isoelectric focusing (IEF) in a polym

193 n array of taxonomic ranges and extended the resolving power of ITS towards earlier nodes of phylogen

194 mporal ERP measurement robustly improved the resolving power of key signatures characteristic of the

195 However, the greater resolving power of LC x LC comes at the price of higher

196 Unfortunately, the resolving power of MCD rarely has been brought to bare o

197 But the ability to employ the resolving power of MCD to follow changes at transition m

198 theoretically could be, given the parentage-resolving power of molecular markers and the huge sizes

199 While the mass accuracy and resolving power of orbitraps have been extensively docum

200 spectrometry (FTICR MS) with an average mass resolving power of over 500 K (M/DeltaM(fwhm)).

201 In particular, the resolving power of p-FAIMS exceeds that of c-FAIMS, typi

202 alphabet sequences to determine the relative resolving power of pairwise interaction-based force fiel

203 y advances have established the accuracy and resolving power of paleobiological information derived f

204 atical approach was developed to analyze the resolving power of second derivative spectroscopy as a f

205 n important initial step that highlights the resolving power of surface charge-based HPLC techniques.

206 sence significantly compromises the temporal resolving power of the auditory system.

207 s (typically less than 10 cm/s) for adequate resolving power of the column ensemble.

208 In comparison to gradient RP-HPLC, the resolving power of the described CEC methods has been fo

209 the smaller fragments is limited only by the resolving power of the gel.

210 The high mass resolving power of the instrument allows unambiguous ide

211 eir motions can be exploited to maximize the resolving power of the instrument.

212 began in the 1800s, but until now the great resolving power of the laser scanning confocal microscop

213 The resolving power of the micro-SPE/PLOT assembly was furth

214 Using nitrogen as a carrier gas, the resolving power of the nano-radial differential mobility

215 Taking advantage of the resolving power of the NST, we measure the cross-section

216 (LC-MS) method that capitalizes on the mass-resolving power of the orbitrap to enable sensitive and

217 ter sensitivity, higher recovery, and higher resolving power of the PLOT column resulted in the incre

218 The resolving power of the scanning endoscopic probe is suff

219 nnel, which has a unit conductance below the resolving power of the single channel technique, located

220 nces in the next few years will increase the resolving power of the technology to provide unprecedent

221 The high ion mobility resolving power of the TIMS analyzer allowed the identif

222 ys have been used for mouse CGH studies, the resolving power of these analyses was limited because hi

223 To test the resolving power of these novel probes, we generate micro

224 Users of T-RFLP frequently overlook the resolving power of well-chosen restriction endonucleases

225 bsolute deviation of 0.36 ppm and an average resolving power of ~520 000 at m/z 6033 for the 26+ char

226 provides similar or better resolution (with resolving powers of >200 for multiply charged peptides)

227 the near-infrared spectrum (corresponding to resolving powers of 10(4)-10(5)).

228 For example, resolving powers of 170,000 and 70,000 were obtained in

229 s equipped with an electrostatic mirror, and resolving powers of 3500-5000 were routinely obtained an

230 ease B (m/z-value 14,900) were measured with resolving powers of 62,000 and 61,000, respectively.

231 ment, the 3D printed IMS is shown to achieve resolving powers of between 24 and 50 in positive ion mo

232 Resolving powers of between 29 and 42 were achieved in n

233 The apparent resolving powers of native-like ions measured using SLIM

234 A parametric study on the dependence of IMS resolving power on drift length, voltage across drift ce

235 describe the influence of mass spectrometry resolving power on profiling metabolomics experiments.

236 ow rates as low as 500 nL/min, with temporal resolving power on the order of 3 min, with analyte load

237 ntribute to separation efficiency, including resolving power, orthogonality, and sample loss.

238 f 90-220) to ultrahigh resolution FT-ICR MS (resolving power over 400k) permitted the identification

239 n strategy was found to greatly increase the resolving power over that obtained for either dimension

240 x 100%, of 56-74% of the maximal conditional resolving power possible.

241 It provides a resolving power R > 60 in IMS mode, and R > 40 in each s

242 nd the high mass-accuracy (<20 ppm) and mass-resolving power (R>5500) of the time-of-flight mass spec

243 This report determined and compared CRM, resolving power (R(m)), and diffusion-limited conditiona

244 At a resolving power (R) exceeding 250, many new features, ot

245 Resolving power ranged from an average value of 50 ms/ms

246 the duplex tags and effectively reducing the resolving power requirement compared to previously repor

247 of above-ambient pressure on ion mobility on resolving power, resolution, and ion current were invest

248 uantifications are possible at 240K and 480K resolving powers, respectively.

249 using OSA-TIMS-FT-ICR MS with high mobility resolving powers (RIMS up to 250), high mass accuracy (<

250 , mass spectral data were acquired with high resolving power (RP > 100,000-190,000) and mass accuracy

251 back and forth: (i) full scan with ultrahigh resolving power (RP = 120,000, mass accuracy </=3 ppm),

252 ions were detected within 1 min with an IMS resolving power (Rp) of approximately 100.

253 Here we examine the relationship among resolving power (Rp), resolution (Rpp), and collision cr

254 le in proteomics because of its unparalleled resolving power, sensitivity and ability to achieve high

255 meter (Thermo Fisher Scientific, CA, USA) at resolving power settings of 15k (7.8 Hz) up to a maximum

256 We demonstrate high mass resolving power single-acquisition FT-ICR-MS analysis of

257 ions substantially higher than a single-peak resolving power suggested.

258 e in terms of both detection sensitivity and resolving power than is currently available by other sep

259 -fold better mass accuracy and 2-fold higher resolving power than similar 7 T systems at the same sca

260 f their differences in pI and offers greater resolving power than that achieved in strong cation exch

261 The device demonstrates better mass resolving power than the radially ejecting halo ion trap

262 y: it can resolve neutral species, provide a resolving power that increases markedly for very large m

263 y, HDX MS experiments employed mass spectral resolving powers that afforded only one peak per nominal

264 Because of limited resolving power, the present FAIMS units are more suitab

265 tron resonance mass spectrometry affords the resolving power to determine an unprecedented number of

266 The technique utilizes the high resolving power to produce images from thousands of ions

267 ment of 2DLC is to consider using its higher resolving power to reduce the analysis time of rather "s

268 This allows previously unattainable resolving powers to be achieved utilizing a small (10.7

269 ant analyte concentration and extremely high resolving power toward protein and peptide mixtures.

270 cialized, their utility was limited by FAIMS resolving power, typically approximately 10-20.

271 cement technique with c-LSFM to increase the resolving power under a large field-of-view, we demonstr

272 tivity, this mass spectrometer provides mass resolving power up to 150,000 fwhm, mass accuracies with

273 olved and identified by TOF HRMS with a mass resolving power up to 7000 (M/deltaMfwhm) and mass accur

274 ately 30 residues employing trapped IMS with resolving power up to approximately 340, followed by tim

275 otein ubiquitin with the same peak width and resolving power up to approximately 400 as for peptides.

276 ntial ion mobility spectrometry (IMS) with a resolving power up to R approximately 300.

277 This increased the resolving power up to the theoretical maximum for every

278 The resolving power (up to 400) is five times the highest pr

279 range (over 7 orders of magnitude), greater resolving power (up to 600), and improved isotope ratio

280 Absorption mode spectra offer superior mass resolving power (up to a factor of 2), mass accuracy, an

281 guration offers higher sensitivity and lower resolving power (up to approximately 2100 at m/z 200), a

282 a two-reflectron configuration yields higher resolving power (up to approximately 4300 at m/z 200) wi

283 Higher mass resolving power usually requires longer scanning times,

284 High resolving power was achieved with low ion densities comb

285 The effect of helium upon IMS resolving power was also studied by introducing a He/N2

286 athematical relationship relating the CCS to resolving power was developed in order to predict the re

287 Close to ideal IMS resolving power was maintained over a significant range

288 A noticeable decrease in the IMS resolving power was observed for ion populations of >10,

289 sing the novel TREC technology; over 420,000 resolving power was observed on melittin [M + 4H] (4+) s

290 Higher resolving power was observed using the atmospheric press

291 An optimal resolving power was obtained at a specific voltage as a

292 The resolving power was optimized with the shift frequency t

293 The column's resolving power was tested by synthesizing peptide analo

294 nal, R c, and actual (or measured), R m, IMS resolving powers were determined and compared for a smal

295 Optimal MS resolving powers were determined to be 240K for labeled

296 alyses of two DiPyrO-labeled samples at 100K resolving power, whereas 3-plex and 6-plex quantificatio

297 ing at the IMS terminus does not degrade IMS resolving power, which exceeds 100 (for singly charged i

298 CAX-PAGE provides high protein resolving power with a theoretical peak capacity of 3570

299 The ion mobility resolving power with ESI (30-35) is comparable to that o

300 rs) were optimized to yield the highest mass resolving power with the least mass discrimination in po