ライフサイエンスコーパス: resorb

1 he flagellar tips and causes the flagella to resorb.

2 lerates G1-S progression by causing cilia to resorb.

3 of its mRNA are present as the tadpole tail resorbs.

4 sapotexanthin, cryptocapsin was found to be resorbed.

5 rk of collapsed tonoplast membranes that are resorbed.

6 of the ectopic MYC-positive structures were resorbed.

7 reduced the number of pits and surface area resorbed.

8 rapidly remodeled and reoriented, as well as resorbed.

9 The PEUU patch was largely resorbed 8 weeks after implantation and the LV wall was

10 Each NRK preferentially resorbed a distinct subset of cilia, depending on the lo

11 amino acids; for instance, droughted plants resorbed a smaller fraction of elemental N from their le

12 planted and, although most were subsequently resorbed, a significant proportion (2 to 2.8%) developed

13 ( D301N) expression enhances osteoclast bone resorbing ability through reorganization of actin cytosk

14 transition to stationary phase, they instead resorb acetate, activate it to acetyl coenzyme A (acetyl

15 ucial mediator of both bone-forming and bone-resorbing actions of PTH, and they underline the complex

16 60 with potent leukocyte-activating and bone resorbing activities.

17 ression of dynamin increased osteoclast bone resorbing activity and migration, whereas overexpression

18 with ST2 showed increased production of bone-resorbing activity and neutralizing antibodies against V

19 ritic cells; and increases osteoclastic bone-resorbing activity as well as osteoclast chemotaxis.

20 est that calcitonin inhibits osteoclast bone resorbing activity in part by down-regulating calpain ac

21 se of 1,25(OH)(2)D(3), it has much less bone resorbing activity in vivo.

22 The bone-resorbing activity of both porins was not inhibited by t

23 The motility and resorbing activity of mu-calpain(-/-) osteoclast-like ce

24 inase-dead Pyk2, markedly inhibited the bone-resorbing activity of wild type osteoclasts and failed t

25 sts and failed to significantly restore bone-resorbing activity to Src(-/-) osteoclast-like cells.

26 te-resistant acid phosphatase staining; bone resorbing activity was assessed by using an osteologic p

27 on of the c-src gene impairs osteoclast bone resorbing activity, causing osteopetrosis.

28 t in osteoclasts markedly reduced their bone resorbing activity, suggesting that phosphorylation of C

29 an important role in osteoclast motility and resorbing activity.

30 produced increased osteoclastogenic and bone-resorbing activity.

31 This material contained potent bone-resorbing activity.

32 obtained, concentrated, and assayed for bone-resorbing activity.

33 ultinucleated giant cell phenotype with bone resorbing activity.

34 d the microtubule network and decreased bone-resorbing activity.

35 hesis that NH2-terminal PTHrP, a potent bone resorbing agent, could also be a member of the synovial

36 ud, zooids from the old generation were also resorbed, albeit delayed to 48-60 h following onset of p

37 elayed, formed no mesoderm by E7.5, and were resorbed almost completely at E8.5.

38 cells, in turn, fuse to form osteoclasts to resorb alveolar bone for the formation of an eruption pa

39 In contrast, plants in drought treatment resorbed amino acids more efficiently (>90%) than those

40 mmersed in connective tissue and appeared to resorb and be replaced by bone.

41 e-sensitive mutant, fla10, existing flagella resorb and new flagella cannot be assembled.

42 deling, bone-embedded osteocytes dynamically resorb and replace the surrounding perilacunar bone matr

43 ilica biomaterials is the rate at which they resorb and the significant role played by interfacial ch

44 Bone is constantly resorbed and formed throughout life by coordinated actio

45 Autologous bone will eventually be resorbed and replaced by the host.

46 becular bone turnover due to imbalanced bone-resorbing and bone-forming activities is a hallmark of o

47 peak of metamorphic climax just before it is resorbed are suppressed in the transgenic limb muscle in

48 correlated with tissues that either grow or resorb at metamorphosis.

49 elop a functional heart tube at E8.5 and are resorbed at approximately E10.5.

50 died abruptly at Day 13, and all were being resorbed at Day 14 of development.

51 (E)7.5, they die by E8.5, and are completely resorbed at E11.5.

52 on, together with its serotonergic cells, is resorbed at metamorphosis.

53 stages of gastrulation and they die and are resorbed between E9.5 and E10.5.

54 eoclasts (OCs) are multinucleated cells that resorb bone and are essential for bone homeostasis.

55 aracterized by the failure of osteoclasts to resorb bone and by several immunological defects includi

56 creased ability of osteoclasts to invade and resorb bone and mineralized cartilage in vivo.

57 crophage/monocyte lineage-derived cells that resorb bone and NF1 haploinsufficient osteoclasts have a

58 S. aureus directly enhanced their ability to resorb bone by promoting cellular fusion.

59 st-natally to form the osteoclasts needed to resorb bone for the eruption pathway.

60 erentiate into multinucleated osteoclasts or resorb bone in vitro and show impaired phosphorylation o

61 defective ruffled borders and were unable to resorb bone in vitro.

62 ma2 (SH2(N+C)) failed to form mature OCs and resorb bone in vitro.

63 The capacity of the osteoclast (OC) to resorb bone is dictated by cytoskeletal organization, wh

64 Osteoclasts from these mice resorb bone matrix poorly, and the structure, stability,

65 Osteoclasts resorb bone through the formation of a unique attachment

66 In particular, osteoclasts resorb bone via a receptor activator of nuclear factor k

67 Osteoclasts resorb bone via the ruffled border, whose complex folds

68 reviously shown that osteoclasts, cells that resorb bone, act as APCs.

69 n animal by the action of osteoclasts, which resorb bone, and osteoblasts, which form new bone.

70 ch is central to the capacity of the cell to resorb bone, is induced by occupancy of the alphavbeta3

71 y of cytokines that stimulate osteoclasts to resorb bone, leading to cancer-mediated destruction of t

72 To resorb bone, OCs form podosomes.

73 steoclasts differentiate from precursors and resorb bone, the identity of an osteoclast precursor (OC

74 nto which they secrete acid and proteases to resorb bone.

75 r influence on the ability of osteoclasts to resorb bone.

76 cells and decreased ability of the cells to resorb bone.

77 ROS stimulate osteoclasts, the cells that resorb bone.

78 g from defective osteoclasts, the cells that resorb bone.

79 tiation of osteoclasts and their capacity to resorb bone.

80 ) in stimulating mouse marrow osteoclasts to resorb bone.

81 te the reduced ability of the osteoclasts to resorb bone.

82 ide channel as the cells become competent to resorb bone.

83 oluble factors that stimulate osteoclasts to resorb bone.

84 specifically in osteoclasts, the cells that resorb bone.

85 that fuse to form multinuclear cells able to resorb bone.

86 rm small actin rings and fail to effectively resorb bone.

87 ly have normal cytoskeletons and effectively resorb bone.

88 s unknown, directly activates osteoclasts to resorb bone.

89 th altered morphology and reduced ability to resorb bone.

90 ly differentiate into mature osteoclasts and resorb bone.

91 ce, which do not form actin rings and do not resorb bone; (e) PYK2 phosphorylation by exogeneous c-Sr

92 Under most conditions, resorbed bone is nearly precisely replaced in location a

93 Osteoclast cultures resorbed bone slices and calcium phosphate substrate.

94 Osteoclasts, the cells capable of resorbing bone, are derived from hemopoietic precursor c

95 ct in osteoclasts, the cells responsible for resorbing bone.

96 Purification of YKL-40 from resorbing bovine nasal cartilage and chondrocyte monolay

97 evelop beyond the egg cylinder stage and are resorbed by 10.5 days of gestation, a phenotype consiste

98 lumen over 12 months in vivo and also fully resorbed by 18 months in the ovine model.

99 arrested after 5.5 days postcoitum (dpc) and resorbed by 8.5 dpc.

100 mmalian inner ear, endolymph is produced and resorbed by a complex series of epithelia.

101 ing 12 micrograms of atRA per g of diet were resorbed by E18.5, whereas those in the group fed 250 mi

102 5 days gestation (E5.5) and were completely resorbed by E8.5.

103 ive streak stages but fail to thrive and are resorbed by E9.5.

104 Allografts apparently are not resorbed by osteoclasts and therefore their continued us

105 However, the amount of bone resorbed by osteoclasts stimulated by 10 nM 19-norD(2),

106 nd need not be removed as they are gradually resorbed by the tissue.

107 are phenotypically defective being unable to resorb calcification.

108 to determine if PRP combined with a rapidly resorbing cancellous allograft would enhance the regener

109 oclasts are the only somatic cells with bone-resorbing capacity and, as such, they have a critical ro

110 We found that the functional bone resorbing capacity was severely impaired in OCLs deplete

111 The addition of Dec-RVKR-CH(2)Cl to resorbing cartilage also partially blocked proteoglycan

112 three isoforms, a major and minor form from resorbing cartilage and a third species from chondrocyte

113 that GW9508, a GRP40 agonist, abolished bone-resorbing cell differentiation.

114 The osteoclast is the principal bone-resorbing cell.

115 xpressed in the osteoclast, the primary bone-resorbing cell.

116 ed in the recruitment and activation of bone resorbing cells associated with focal bone erosions.

117 ent the development of OCPs into mature bone-resorbing cells could simultaneously prevent bone resorp

118 Osteoclasts are bone-resorbing cells derived from hematopoietic precursors of

119 Osteoclasts (OC) are bone-resorbing cells derived from the monocyte/macrophage lin

120 Osteoclasts are bone-resorbing cells essential for skeletal development, home

121 Osteoclasts are bone-resorbing cells essential for skeletal remodeling.

122 In conclusion, the resorbing cells in RA exhibit a definitive osteoclastic

123 Osteoclasts are bone resorbing cells of hematopoietic origin; however, a prog

124 ancer grows, osteoclasts, the principal bone-resorbing cells of the body, are recruited to and activa

125 ed myeloid cells that are the principal bone-resorbing cells of the skeleton.

126 Osteoclasts (OCs) are bone-resorbing cells that are formed from hematopoietic precu

127 Osteoclasts are bone-resorbing cells that are important for maintenance of bo

128 ly induce apoptosis in osteoclasts, the bone resorbing cells, and this may play a role in inhibition

129 Osteoclasts, the only bone-resorbing cells, are central to the pathogenesis of oste

130 Osteoclasts are bone-resorbing cells, but they also secrete and respond to cy

131 of increased numbers of osteoclasts, or bone-resorbing cells.

132 apoptosis of osteoclasts, the principal bone-resorbing cells.

133 Osteoclasts are the sole bone-resorbing cells.

134 amined release of ECM-bound TGF-beta by bone resorbing cells.

135 d activation of osteoclasts, the normal bone-resorbing cells.

136 one-forming cells, and osteoclasts, the bone-resorbing cells.

137 tures assume organization typical of active, resorbing cells.

138 where they fuse to form multinucleated bone-resorbing cells.

139 Because most cells resorb cilia/flagella before cell division, these data i

140 ich assembled cilia at high cell density and resorbed cilia at low cell density.

141 he treated root surface height for the rapid-resorbing collagen and 53% for the ePTFE membrane (diffe

142 tissues the way the less crosslinked, rapid-resorbing collagen did.

143 r, the connective tissue repair to the rapid-resorbing collagen group root surfaces was often associa

144 indicated that the highly cross-linked, slow-resorbing collagen membrane did not integrate with the t

145 It was concluded that the rapid-resorbing collagen membranes and the ePTFE membranes see

146 l connective tissue repair, whereas the slow-resorbing collagen membranes were unsuccessful in this e

147 mination of root surfaces treated with rapid-resorbing collagen or ePTFE membranes revealed substanti

148 ately 50% of the surfaces of the bone slices resorbed compared with only 6% in cultures treated with

149 as early as embryonic day 4.5 (E4.5) and are resorbed completely by E8.5.

150 and thus the amount of bone that osteoclasts resorb could also be enhanced following estrogen deficie

151 (AgP) gingival fibroblasts produce the bone-resorbing cytokine IL-6.

152 ion, expression of the proinflammatory, bone-resorbing cytokine interleukin-6, and in vitro bone reso

153 teoclasts in vitro, but not their ability to resorb dentin.

154 one-like tissue was found within lesions, on resorbed dentin, or on the root surface in 27% of teeth.

155 ere markedly impaired in their ability to be resorbed despite engulfment of zooid-derived cell corpse

156 hilic line and bone necrosis that was slowly resorbed during the repair process.

157 No resorbed embryos were found at embryonic day (E) 17.5, i

158 This failure to resorb established calcifications may contribute to the

159 ough their capacity to deposit, remodel, and resorb extracellular matrix and to promote tissue vascul

160 MMP13, VEGF, Osteopontin) and secreted bone-resorbing factors (PTHrP, IL8) promoting osteolytic dise

161 rrow precursor cells in the presence of bone-resorbing factors, indicating that OSCAR may be an impor

162 y for maximal OCL formation by multiple bone resorbing factors.

163 ll formation in the presence of several bone-resorbing factors.

164 interstitial fluid, salts, small molecules, resorbed fat, and cells to the bloodstream.

165 methylated proteins have been identified in resorbing flagella, using antibodies specific for asymme

166 sed in regenerating flagella, and highest in resorbing flagella.

167 and efficient removal of interstitial fluid resorbed from the loop of Henle and collecting ducts.

168 mation of the sealing ring and thus the bone-resorbing function of osteoclasts.

169 TR1 also strongly inhibited bone-resorbing function on dentine slices by mature osteoclas

170 o the facile formation of multinucleate bone-resorbing giant cells.

171 C filter can be safely deployed in swine and resorbs gradually over the 32-week testing period.

172 ts/stromal cells in response to various bone resorbing hormones.

173 Bone-resorbing human and murine cytokines such as interleukin

174 occluded artery for 6 mo and are completely resorbed in 2 y.

175 The pancreatic pseudocyst was resorbed in eight months.

176 e and then allowing the silk to dissolve and resorb initiates a spontaneous, conformal wrapping proce

177 completion of function, the device is safely resorbed into the body, within a programmable period.

178 tadpole completed its metamorphosis without resorbing its tail.

179 re involved in pulling up the "back end" and resorbing lamellipodial membrane protrusions.

180 Membrane exposure was typical for the slow-resorbing membrane in contrast to the rapid-resorbing me

181 The inferiority of the slow-resorbing membrane was evident by the extensive clinical

182 -resorbing membrane in contrast to the rapid-resorbing membrane which remained covered.

183 line, to differentiate into osteoclasts and resorb mineralized matrix in vitro.

184 o Slc4a2-deficient osteoclasts are unable to resorb mineralized tissue and cannot form an acidified,

185 because the interproximal bone heights were resorbed more adjacent to the wider defects during the p

186 Osteoclasts are bone-resorbing multinucleated cells that are derived from the

187 Bone-resorbing multinucleated osteoclasts that play a central

188 These cells form high numbers of bone-resorbing OCL when cultured using standard conditions fo

189 e immortalized OCL precursors that form bone-resorbing OCL with an efficiency that is 300-500 times g

190 on glass and in the sealing zone in actively resorbing OCLs on bone; 3) p130(Cas) and PYK2 form a sta

191 heir differentiation to multinucleated, bone-resorbing OCs (P < 0.00002) in a receptor activator of n

192 L immunostaining in vivo on VEC located near resorbing OCs in regions undergoing active bone turnover

193 ifferential transcriptomic profiling of bone-resorbing OCs versus nonresorbing MGCs to generate a lis

194 x formation, the starter matrix is degraded, resorbed, or metabolized.

195 ary cell culture system (RCCS) enhanced bone resorbing osteoclast (OCL) differentiation.

196 affect both bone-forming osteoblast and bone-resorbing osteoclast cell activity.

197 been limited mainly to their effects on bone-resorbing osteoclast cells, with implications that some

198 wth/apoptosis, immune cell function and bone-resorbing osteoclast formation, the expression of TRAIL

199 t an essential signaling complex in the bone-resorbing osteoclast, and, therefore, each is a candidat

200 ing of degraded collagen, as typified by the resorbing osteoclast, may provide the cell with a regula

201 ivator of NF-kappaB ligand), a critical bone resorbing osteoclastogenic factor, has an important role

202 by the coupled actions of hematopoietic bone-resorbing osteoclasts (OCs) and mesenchymal bone-forming

203 Because bone-resorbing osteoclasts (OCs) are derived from the monocyt

204 d to bone and differentiate into active bone-resorbing osteoclasts (OCs), thus providing evidence tha

205 coordinated activity between actions of bone-resorbing osteoclasts and bone forming-osteoblasts.

206 alyze underlying cellular mechanisms in bone-resorbing osteoclasts and bone-forming osteoblasts in mi

207 reduced, respectively, the formation of bone-resorbing osteoclasts and bone-forming osteoblasts.

208 ed MSCs (ASCs) on in vitro formation of bone-resorbing osteoclasts and pathological bone loss in the

209 both osteoclast precursors and mature, bone-resorbing osteoclasts as shown by qRT-PCR and Western an

210 phatase (cyt-PTPe) supports adhesion of bone-resorbing osteoclasts by activating Src downstream of in

211 t fashion and suppressed development of bone-resorbing osteoclasts by downregulating NFATc1 through t

212 Differentiation of bone-resorbing osteoclasts from hematopoietic precursors depe

213 e, we report the stepwise generation of bone-resorbing osteoclasts from human embryonic and induced p

214 Bone-resorbing osteoclasts have been identified as important

215 and MMP-9 were found to be localized to bone-resorbing osteoclasts in human breast-to-bone metastases

216 io between bone-forming osteoblasts and bone-resorbing osteoclasts in part through the induction of o

217 Inhibition of the differentiation of bone-resorbing osteoclasts is an effective strategy for the t

218 Matrix-producing osteoblasts and bone-resorbing osteoclasts maintain bone homeostasis.

219 ally important cell-surface proteins on bone-resorbing osteoclasts represents a promising approach fo

220 Bone-resorbing osteoclasts significantly contribute to osteop

221 ing activity of V-ATPase, early responses of resorbing osteoclasts to inhibition of phosphatidylinosi

222 , which is identified in the sealing ring of resorbing osteoclasts, also demonstrates colocalization

223 opose that they are not only sources of bone-resorbing osteoclasts, but also of immune cells that inf

224 nst myeloma, also block the activity of bone-resorbing osteoclasts.

225 major collagenolytic enzyme produced by bone-resorbing osteoclasts.

226 actions of bone-forming osteoblasts and bone-resorbing osteoclasts.

227 ination of bone-forming osteoblasts and bone-resorbing osteoclasts.

228 recruitment, formation, and activity of bone-resorbing osteoclasts.

229 including bone forming osteoblasts and bone resorbing osteoclasts.

230 s sort results from elevated numbers of bone-resorbing osteoclasts.

231 is the main adhesion-induced kinase in bone-resorbing osteoclasts.

232 ids required for protein prenylation in bone-resorbing osteoclasts.

233 cid phosphatase-positive multinucleated bone-resorbing osteoclasts.

234 ut interactions between tumor cells and bone-resorbing osteoclasts.

235 ivities of bone-forming osteoblasts and bone-resorbing osteoclasts.

236 a significant increase in the number of bone-resorbing osteoclasts.

237 ivities of bone-forming osteoblasts and bone-resorbing osteoclasts.

238 tion of osteoclast precursors to mature bone-resorbing osteoclasts.

239 aling and regulates actin remodeling in bone-resorbing osteoclasts.

240 ytes, macrophages, dendritic cells, and bone-resorbing osteoclasts.

241 ivities of bone-forming osteoblasts and bone-resorbing osteoclasts.

242 rophages, foreign body giant cells, and bone-resorbing osteoclasts.

243 adial bone growth, increased numbers of bone-resorbing periosteal osteoclasts, and increased bone fra

244 thepsin K-positive DCs were observed in bone-resorbing pits.

245 as successfully captured by the filter until resorbed (range, 1-4 weeks).

246 option for vertical augmentation of severely resorbed ridges.

247 e viable in the pre-implantation period, but resorb shortly after implantation.

248 Also, both the total resorbed surface area and number of resorption pits form

249 t resorption was quantified by measuring the resorbed surface area of the calcium phosphate substrate

250 ally in the remodeling intestine but not the resorbing tail, and that c-Myc was induced by T3 prior t

251 the remodeling and growing body than in the resorbing tail.

252 d RXRbeta) are expressed ubiquitously in the resorbing tail.

253 easing the ability of alveolar epithelium to resorb the edema should lead to benefits for patients wi

254 Arf-null mice fail to resorb the hyaloid vasculature within the ocular vitreou

255 ess OC degradation enzymes but are unable to resorb the mineral matrix.

256 Osteoclasts resorb the mineralized matrices formed by chondrocytes o

257 ere were multinucleated, TRAP-positive cells resorbing the hypertrophic cartilage matrix.

258 eek, osteoclast activity was responsible for resorbing the necrotic bone, which in turn stimulated th

259 n all, 46 of 50 cells regenerated, either by resorbing the remaining neurites and elaborating a new n

260 responsible for dissolving the notochord and resorbing the tail.

261 in the delayed response class is highest in resorbing tissues and higher in the tail than in the bod

262 ocyst, the central regions of which fuse and resorb to leave three fluid-filled canals.

263 DFDBA and MFDBA are resorbed very slowly and apparently do not contribute to

264 h all of the constituent materials naturally resorb via hydrolysis and/or metabolic action, eliminati

265 ed process in which calcium is deposited and resorbed via a multiple phase process.

266 al, as evidenced by their reduced ability to resorb whale dentin in vitro and the significant hypocal

267 They start resorbing when cells re-enter the cell cycle (S phase) a

268 Bovine nasal cartilage was stimulated to resorb with the addition of interleukin-1alpha (IL-1alph

269 eoconductive potential; and 4) HY appears to resorb within a 12-week healing interval in the absence

270 The "old" zooids and their organs are resorbed within 24-36 h (programmed cell removal).

271 my), the budectomized zooids were completely resorbed within 36-48 h following onset of programmed ce