ライフサイエンスコーパス: respiratory epithelium

1 preserved ciliated pseudostratified columnar respiratory epithelium.

2 amily and mediates bacterial adhesion to the respiratory epithelium.

3 of the virus to interact with and cross the respiratory epithelium.

4 rentiation of early tracheal epithelium into respiratory epithelium.

5 ma, haemorrhage and rapid destruction of the respiratory epithelium.

6 normal tissue to the reproductive tracts and respiratory epithelium.

7 some morphological features consistent with respiratory epithelium.

8 igration of B. cenocepacia through polarized respiratory epithelium.

9 e also discovered that Reg3g is a marker for respiratory epithelium.

10 ed olfactory epithelium and to the adjoining respiratory epithelium.

11 ling and cell shedding in homeostasis of the respiratory epithelium.

12 f plunc was up-regulated after bulbectomy in respiratory epithelium.

13 receptor, which is expressed by cells in the respiratory epithelium.

14 ncing delivery of tobacco carcinogens to the respiratory epithelium.

15 epithelial cation and anion transport in the respiratory epithelium.

16 rocess that probably depends on adherence to respiratory epithelium.

17 highly localized to the microvilli layer of respiratory epithelium.

18 vaccine to mucosal inductive tissues and the respiratory epithelium.

19 mediate attachment of Bordetella species to respiratory epithelium.

20 d to alveolar Type II and Clara cells in the respiratory epithelium.

21 oximal bronchiolar epithelium and the distal respiratory epithelium.

22 n exclusive human pathogen which infects the respiratory epithelium.

23 ung tumor cell line representative of distal respiratory epithelium.

24 or cell line (H441) representative of distal respiratory epithelium.

25 and promote its internalization into the WD respiratory epithelium.

26 rapid spread of the virus through the upper respiratory epithelium.

27 CsA were able to prevent the loss of normal respiratory epithelium.

28 Importantly, LFM also prevented the loss of respiratory epithelium.

29 al tissue showed minimal binding to ciliated respiratory epithelium.

30 nfluenza virus infection of MHC class II -/- respiratory epithelium.

31 the transcription of genes expressed in the respiratory epithelium.

32 initiates infection by colonizing the upper respiratory epithelium.

33 ages, neutrophils, vascular endothelium, and respiratory epithelium.

34 rsally located cells in olfactory sensory or respiratory epithelium.

35 pt expression in testis compared to ciliated respiratory epithelium.

36 th the first line of our airway defense, the respiratory epithelium.

37 teins and is expressed in nasopharyngeal and respiratory epithelium.

38 thelium is not a good surrogate for the lung respiratory epithelium.

39 iates infection by colonizing the genital or respiratory epithelium.

40 TLR-dependent inflammatory responses of the respiratory epithelium.

41 tiate infection by colonizing the genital or respiratory epithelium.

42 ganelle, that mediates adherence to the host respiratory epithelium.

43 mily and mediates bacterial adherence to the respiratory epithelium.

44 latter is detected in histologically normal respiratory epithelium.

45 procal signaling from the vasculature to the respiratory epithelium.

46 it from neuroendocrine catecholamines on the respiratory epithelium.

47 hil chemoattractant that is mobilized in the respiratory epithelium after allergic stimulation.

48 show that RB is essential for repair of the respiratory epithelium after cytotoxic damage and suppor

49 ne gammaherpesvirus MHV-68 multiplies in the respiratory epithelium after intranasal inoculation, the

50 ting a basolaterally located receptor in the respiratory epithelium, alphaherpesviruses have generate

51 nked glycoprotein that mediates adherence to respiratory epithelium, an essential early step in the p

52 ng sacculation, induced proliferation in the respiratory epithelium and accelerated lung tumor growth

53 otility are required for colonization of the respiratory epithelium and are mediated largely by a dif

54 proteins that promote bacterial adherence to respiratory epithelium and are the predominant targets o

55 Viral antigens were localized to ciliated respiratory epithelium and cells of submucosal glands an

56 they form cysts that express several TSA of respiratory epithelium and exhibit some morphological fe

57 ic-oxide synthases (NOS) are abundant in the respiratory epithelium and generate the NO radical, whic

58 and MUC16) genes, which are exclusive to the respiratory epithelium and goblet cells of bronchial str

59 S. pneumoniae that colonized the respiratory epithelium and grew in the bloodstream were

60 concomitant with NF-kappaB activation in the respiratory epithelium and initiation of the inflammator

61 trate that T2R38 is expressed in human upper respiratory epithelium and is activated in response to a

62 syncytial virus (RSV) preferentially infects respiratory epithelium and is an important cause of lowe

63 nor trachea repopulated with the recipient's respiratory epithelium and mesenchymal stromal cells.

64 velopment, including dilated airspaces, thin respiratory epithelium and mesenchyme, and elastin fiber

65 rmo1-Cre mice to delete Wls in the embryonic respiratory epithelium and mesenchyme, respectively.

66 mechanism by which this organism adheres to respiratory epithelium and seeds joints and bones.

67 anted airways remodeled with a flattening of respiratory epithelium and significant subepithelial fib

68 rt a role for CFTR in differentiation of the respiratory epithelium and suggest that its expression l

69 the morphology and level of chimerism of the respiratory epithelium and the degree of airway remodeli

70 gly inhibited in several tissues such as the respiratory epithelium and the fallopian tube.

71 olarity of alphaherpesvirus infection in the respiratory epithelium and the role of respiratory epith

72 dependent on reciprocal interactions between respiratory epithelium and the underlying vasculature, e

73 scle actin (alphaSMA) expression in vessels, respiratory epithelium, and interstitium of phosphatase-

74 tial relationship between mast cells and the respiratory epithelium, and the importance of tightly re

75 Thus, ATP and purinergic signaling in the respiratory epithelium are critical sensors for airway e

76 Lactobacilli, when targeted to the respiratory epithelium, are highly effective at suppress

77 n embryonic neural tube, spinal ganglia, and respiratory epithelium, as well as in developing cartila

78 ls derived from human vaginal, cervical, and respiratory epithelium, as well as increasing adherence

79 LFM groups, respectively; the percentage of respiratory epithelium at 14 days was 0%, 21%, and 95%.

80 RPM groups, respectively; the percentage of respiratory epithelium at 21 days was 0%, 39%, 86%, and

81 productive phase of MHV-68 infection in the respiratory epithelium but are maintained at relatively

82 al with widespread dysplastic changes in the respiratory epithelium but no overt carcinoma.

83 nal expansion, and reconstitution of injured respiratory epithelium by fusion-independent mechanisms.

84 gest that B. cenocepacia traverses polarized respiratory epithelium by the dephosphorylation and diss

85 It specializes in infection of the ciliated respiratory epithelium, causing disease of variable seve

86 protein affected the olfactory, but not the respiratory, epithelium, causing severe reduction of the

87 n across in vitro model systems of polarized respiratory epithelium consisting of 16HBEo cells transf

88 The respiratory epithelium consists of lung sentinel cells,

89 Resident alveolar macrophages and respiratory epithelium constitutes the first line of def

90 y, H7N9 viruses showed a greater tropism for respiratory epithelium covering nasal passages and nasop

91 Mycoplasma adherence to the respiratory epithelium (cytadherence) is required for co

92 Genetic deletion of Foxm1 from mouse respiratory epithelium during initial stages of lung dev

93 tudy, Foxm1 was deleted conditionally in the respiratory epithelium (epFoxm1(-/-)).

94 n that enzymatically removes sialic acids on respiratory epithelium, exhibits potent antiviral activi

95 Human respiratory epithelium expresses inducible nitric oxide

96 ung alveolar regions (site of infection) and respiratory epithelium for controls.

97 ors are effective to specifically target the respiratory epithelium for either corrective gene therap

98 consequence of the change in function of the respiratory epithelium from chloride secretion to sodium

99 normal baseline data for nasal transitional/respiratory epithelium from healthy rats.

100 generation of mature multiciliated cells in respiratory epithelium from iPSCs is a significant advan

101 anelle which functions in adherence to human respiratory epithelium, gliding motility, and cell divis

102 Respiratory epithelium has been increasingly recognized

103 (AdV)-mediated gene transfer to the ciliated respiratory epithelium has hindered gene transfer strate

104 and precisely how M. pneumoniae injures the respiratory epithelium has remained a mystery for >50 ye

105 The TLRs are important components of the respiratory epithelium host innate defense, enabling the

106 al to the tumors were detected in the normal respiratory epithelium in 9 of 21 (43%) patients with EG

107 e investigated by using differentiated human respiratory epithelium in air-liquid interface cultures.

108 s organism also commonly colonizes the upper respiratory epithelium in an asymptomatic fashion.

109 nspecific injury models, we investigated the respiratory epithelium in an immune-specific orthotopic

110 is limited to the superficial layers of the respiratory epithelium in immunocompetent individuals.

111 lays a crucial role in the maturation of the respiratory epithelium in late gestation, being required

112 ill be useful to interrogate the role of the respiratory epithelium in multiple lung diseases.

113 Given the proposed role of respiratory epithelium in nonspecific injury models, we

114 is not clear how the virus can traverse the respiratory epithelium in order to initiate infection in

115 LLT1 expression by the respiratory epithelium in response to respiratory-virus

116 ms responsible for the spread of MV into the respiratory epithelium in the late stages of the disease

117 The involvement of the respiratory epithelium in the mechanisms of CRS is poorl

118 This study highlights the role of the respiratory epithelium in the trafficking of T lymphocyt

119 ied to a perfused preparation of human nasal respiratory epithelium in vitro.

120 GATA-6 is co-expressed with TTF-1 in the respiratory epithelium in vivo and respiratory epithelia

121 delivery paralleled hpIgR expression in the respiratory epithelium in vivo and was not increased by

122 rly seen in the liver, intestine, thymus and respiratory epithelium including nasopharynx, trachea an

123 iption of genes expressed selectively in the respiratory epithelium including pulmonary surfactant A,

124 was greatly enhanced upon destruction of the respiratory epithelium integrity with EGTA or N-acetylcy

125 Adherence to respiratory epithelium is an important step in the proce

126 Maintaining the integrity of the respiratory epithelium is critical for an effective host

127 r findings demonstrate that integrity of the respiratory epithelium is crucial in the host's innate d

128 The cellular composition of the murine respiratory epithelium is established during development

129 antiproliferative activity of P. carinii on respiratory epithelium is mediated in part through modul

130 Expression of MK in the respiratory epithelium is regulated by hypoxia and HIF-1

131 Mycoplasma attachment to the host respiratory epithelium is required for colonization and

132 The respiratory epithelium is subject to continuous environm

133 expression of activated Kras(G12D) in mouse respiratory epithelium is sufficient to induce lung aden

134 Oncogenic K-Ras expression in the respiratory epithelium is sufficient to initiate NSCLC t

135 Respiratory epithelium is the target of therapies, such

136 pha deletion, that loss of C/EBPalpha in the respiratory epithelium leads to respiratory failure at b

137 y, perinatal overexpression of VEGF-C in the respiratory epithelium led to a condition resembling hum

138 features of human airway rejection (loss of respiratory epithelium, luminal granulation tissue, lymp

139 the progression of MV infection through the respiratory epithelium may involve pathways other than d

140 ata suggest that hantavirus infection of the respiratory epithelium may play an important role in the

141 Under conditions of airway inflammation, the respiratory epithelium may serve an important role in th

142 on of influenza A virus replication to mouse respiratory epithelium means that this host response is

143 which subsequently reconstitute as aneuronal respiratory epithelium (metaplasia).

144 Expression of Spdef in the respiratory epithelium of adult transgenic mice caused g

145 tors have been used for gene transfer to the respiratory epithelium of experimental animals and indiv

146 Expression of GM-CSF in the respiratory epithelium of GM-/- mice improved bacterial

147 the synthesis of GM-CSF was directed to the respiratory epithelium of GM-CSF-hull mutant mice (GM-/-

148 The respiratory epithelium of humans and animals is frequent

149 r the human thrombopoietin (TPO) cDNA-to the respiratory epithelium of immunocompetent Balb/c mice.

150 methylation of the p16 and MGMT genes in the respiratory epithelium of individuals at high risk for l

151 d inflammatory immune cells infiltrating the respiratory epithelium of mice exposed to OVA or HDM.

152 cells were found in lymphoepithelium and not respiratory epithelium of nasopharyngeal tonsils or aden

153 ed in the histologically normal and abnormal respiratory epithelium of smokers.

154 f expression of the GRP receptor mRNA in the respiratory epithelium of some individuals with a histor

155 vine conglutinin (Cong) was expressed in the respiratory epithelium of SP-D gene-targeted (SP-D(-/-))

156 which SP-D was conditionally replaced in the respiratory epithelium of SP-D(-/-) mice.

157 alcineurin b1 (Cnb1) gene was deleted in the respiratory epithelium of the fetal mouse.

158 of a bioactive Fc-fusion protein across the respiratory epithelium of the mouse in vivo.

159 , the RB gene was selectively deleted in the respiratory epithelium of the mouse.

160 consistently, the viruses caused necrosis in respiratory epithelium of the nasal cavity, trachea, bro

161 AAV-CFTR was administered to the respiratory epithelium of the nose or lung of rhesus mac

162 CAS was also concentrated in the respiratory epithelium of the trachea and in axons and P

163 Expression of TGF-beta 1 in the developing respiratory epithelium of transgenic mice arrested lung

164 e mutated protein was targeted to the distal respiratory epithelium of transgenic mice.

165 Targeted expression of LysM(D53S) in the respiratory epithelium of wild-type (LysM(+/+)/LysM(D53S

166 Haemophilus influenzae (NTHi) adheres to the respiratory epithelium or, in the case of epithelial dam

167 lective deletion of the Hgf receptor gene in respiratory epithelium phenocopies the malformation of s

168 The respiratory epithelium plays a central role in innate im

169 y proinflammatory cytokines in the asthmatic respiratory epithelium plays a central role in the obser

170 The respiratory epithelium plays a central role in the regul

171 Adhesion to the respiratory epithelium plays an important role in Haemop

172 how that Foxa2, expressed selectively in the respiratory epithelium, plays a critical role in regulat

173 deletion of Foxm1 from Kras(G12D)-expressing respiratory epithelium prevented the initiation of lung

174 Mycoplasma pneumoniae adsorbs to host respiratory epithelium primarily by its attachment organ

175 both normal and abnormal nasal olfactory and respiratory epithelium, pulmonary alveolar macrophages,

176 inguish NALT M cells from other cells of the respiratory epithelium (RE), we performed lectin histoch

177 ies than more anterior regions closer to the respiratory epithelium (Regions 3 and 4).

178 In response to infections and irritants, the respiratory epithelium releases the alarmin interleukin

179 but the processes favoring its spread in the respiratory epithelium remain poorly defined.

180 Colonization of the respiratory epithelium requires proper assembly of a com

181 These data provide a model wherein the respiratory epithelium responds to hypoxia via HIF-1alph

182 Selective inactivation of the Vegf-A gene in respiratory epithelium results in an almost complete abs

183 lpha-mediated activation of NF-kappaB in the respiratory epithelium similarly induces p65 denitrosyla

184 Dox administration induced marked respiratory epithelium-specific FasL mRNA and protein up

185 bsp. hominissuis to bind and invade the host respiratory epithelium, suggesting new potential targets

186 receptors, which are characteristic of human respiratory epithelium, than for Neu5Ac(alpha2-3)Gal-con

187 nza viral infections result in damage to the respiratory epithelium that facilitates secondary infect

188 ll as those regulating the maturation of the respiratory epithelium that is required for lung functio

189 el mechanism for field carcinogenesis in the respiratory epithelium that may be of importance in asse

190 nt to mediate the metaplastic changes in the respiratory epithelium that occur in pathological condit

191 ation and morphogenesis were observed in the respiratory epithelium, the bronchiolar smooth muscle, a

192 ellular adhesion molecule-1 (ICAM-1), by the respiratory epithelium, the hypothesis has been proposed

193 on respiratory virus, is known to infect the respiratory epithelium, the mechanism of infection and t

194 ion cleared the virus from Fas+/+ and Fas-/- respiratory epithelium, the P-/- effectors were operatio

195 Adhesion of NTHI to the respiratory epithelium, therefore, upregulates the expre

196 ent, including undilated airspaces, cuboidal respiratory epithelium, thickened mesenchyme, and lack o

197 ce of M. hyopneumoniae to the cilia of swine respiratory epithelium through an interaction involving

198 s used to study the susceptibility of the CF respiratory epithelium to P. aeruginosa strain PAK and t

199 iginating from periodontal tissues may alter respiratory epithelium to promote infection by respirato

200 Transfer from the respiratory epithelium to regional lymph nodes appears t

201 To further explore the reaction of the respiratory epithelium to the fungus, we analyzed the pr

202 mimicking the microenvironment of the human respiratory epithelium, to study the production and regu

203 ESC-derived Nkx2.1+ progenitor cells formed respiratory epithelium (tracheospheres) when transplante

204 Expressed by the embryonic respiratory epithelium, VEGF-A signals endothelial cells

205 the inaccessible CF airways by targeting the respiratory epithelium via the human polymeric immunoglo

206 to inaccessible CF airways by targeting the respiratory epithelium via the polymeric immunoglobulin

207 ation studies demonstrated that the infected respiratory epithelium was a major source of IFN-alpha/b

208 plunc up-regulation in respiratory epithelium was confirmed by Northern blot an

209 tive pulmonary disease (COPD) human ciliated respiratory epithelium was determined.

210 ide anion, a potent mediator that can damage respiratory epithelium, was markedly increased after 2-2

211 ecause adenovirus is adept in binding to the respiratory epithelium, we tested the adenovirus 2 fiber

212 n tracheal graft narrowing and protection of respiratory epithelium were as follows: After 14 days of

213 bs showed that certain leukocytes as well as respiratory epithelium were intensely immunoreactive, an

214 determine the chemokine response pattern of respiratory epithelium when infected with respiratory sy

215 sease-specific human lung progenitors formed respiratory epithelium when subcutaneously engrafted int

216 though isografts appeared patent with normal respiratory epithelium when they were removed.

217 HMW) adhesins that mediate attachment to the respiratory epithelium where they interact with the host

218 y synthesized in subsets of cells lining the respiratory epithelium, where its expression is regulate

219 lung cell types except for smooth muscle and respiratory epithelium, which have a IV-2 and a IV-1 pre

220 e disease begins with bacterial adherence to respiratory epithelium, which is dependent on type IV pi

221 heterogeneity are reciprocally expressed by respiratory epithelium, which raises interesting questio

222 This is the first protein found in respiratory epithelium whose expression is regulated by

223 These results suggest that infection of the respiratory epithelium with rhinovirus can antagonize to

224 Ps were not readily taken up into or through respiratory epithelium, with very low silver levels foun

225 the contagion measles virus (MV) crosses the respiratory epithelium within myeloid cells that express

226 , specifically to the lumenal surface of the respiratory epithelium, within the airway surface fluid,