ライフサイエンスコーパス: response

1 ment cycle 2; ten (77%) of the 13 achieved a response.

2 ining exosomes is important for a proper LPS response.

3 lamic circuit coordinating the global stress response.

4 ed multiple TFs influencing asthma treatment response.

5 ties to limit an exaggerated adaptive immune response.

6 with varying natural history and therapeutic response.

7 in raising an effective anti-melanoma immune response.

8 tment tumour burden correlated with clinical response.

9 n is key for the observed leap in mechanical response.

10 , a key mediator of the cellular antioxidant response.

11 subgenual cingulate predicts antidepressant response.

12 than the subdominant HLA-B*14-restricted Gag response.

13 dent enhancer activity during the DNA damage response.

14 ed to identify predictive factors of therapy response.

15 ) infection by regulating type I IFN (IFN-I) response.

16 ting preclinical disease-modifying treatment response.

17 ch from proinflammatory to anti-inflammatory responses.

18 se in driving scopolamine-induced behavioral responses.

19 f how ubiquitin signals control inflammatory responses.

20 in serum-free medium mounted strong anti-Id responses.

21 ains, indicating species and strain-specific responses.

22 CB) therapies can unleash anti-tumour T-cell responses.

23 (IFNs) are essential mediators of antiviral responses.

24 ificant differences in the mean rod-mediated responses.

25 specific difference in human postvaccination responses.

26 ignals contribute to the induction of hyphal responses.

27 to optimize the balance of growth and stress responses.

28 for rapid and precise initiation of startle responses.

29 e CXCL14 and suppression of antitumor immune responses.

30 mutants showed elevated chitin-induced rapid responses.

31 ell maturation and promotion of inflammatory responses.

32 augmentation of pancreatic and intestinal BF responses.

33 vation by DMXAA on enhancing proinflammatory responses.

34 onal specificities of vaccine-induced immune responses.

35 mplification but impaired auditory brainstem responses.

36 st 3 years of TKI treatment and in molecular response 4.5 (MR4.5) with undetectable BCR-ABL1 transcri

37 V) and who do not have a sustained virologic response after treatment with regimens containing direct

38 e break-down products are involved in stress response against herbivores, pathogens, and abiotic stre

39 kd mosquitoes elicited a potent melanization response against Plasmodium berghei ookinetes and exhibi

40 Thus, augmenting host immune responses against Mycobacterium tuberculosis by harnessi

41 he host transcriptomic, epigenetic and virus response also has the potential to provide deeper insigh

42 otocurrent generation through a photovoltaic response and electroluminescence within a single device.

43 critical mediators of any anti-viral immune response and IFNbeta has been implicated in the temporar

44 als complex gene networks which control drug response and illustrates how such data can add substanti

45 ne-environment interactions relevant to drug response and immunity, and we highlight how such improve

46 u temperatures, possessing a suite of stress response and nutrient cycling genes to fix carbon under

47 rted the frequency of new immune patterns of response and progression.

48 Treatment response and recurrence were analyzed with uni- and mult

49 ced metabolic dysregulation and inflammatory responses and affected the immune cell content of the sp

50 of PLD4 modulated innate and adaptive immune responses and attenuated the upregulation of the TGF-bet

51 nd isocyanates elicit similar nasal proteome responses and the profiles of welders and healthy contro

52 by which noninflammatory SF modulate Th cell responses and to determine the immunosuppressive efficac

53 ways to control metabolism, oxidative stress response, and cell cycle.

54 to ART when effects on viremia and clinical response are not met.

55 Stimulus-related neural responses are increased for the attended stimulus.

56 Within the LGN, neuronal responses are often suppressed by stimuli that extend be

57 tory breast cancer chest wall metastases but responses are short-lived.

58 common and harmless substances show the same response as the hazardous target substances.

59 has developed, researchers have used vaccine responses as a tool to characterize the phenotypes of pa

60 roportion of patients with complete clinical response at day 7 was significantly higher (P = .001) in

61 strategies to elicit broad and potent immune responses based on the immunomodulatory properties of Fc

62 to play a central role in the peroxynitrite response, because the ohr mutant was more sensitive than

63 tude and time course of the NMDA-DeltaCa(2+) responses between the two experimental groups.

64 (G3P) is important for environmental stress responses by eukaryotic microalgae.

65 shape of the measured resonant elastic X-ray response can be explained with the "site-selective" Mott

66 s that are likewise capable of multi-stimuli response can form the basis of programmable molecular sy

67 onses, whereas high-dose immunization primes responses characterized by regulatory T (Treg) cells and

68 used log-linear and nonlinear concentration-response coefficients from previous studies to estimate

69 acaques elicited a rapid and robust antibody response, conferring complete protection upon challenge.

70 Thus two distinct proteotoxic stress responses control phospholipid metabolism.

71 Ferricyanide voltammetric responses correlate with the increased permeability of t

72 received each elagolix dose met the clinical response criteria for the two primary end points than di

73 apture the overlap between TNF-induced noisy response curves.

74 or senescence as outcomes of the DNA damage response (DDR).

75 We identified autophagy as a pivotal cell response determining the efficiency of AAVs intracellula

76 -15(-/-) mice will have reduced inflammatory responses during the development of allergic airway dise

77 lysis revealed the presence of Zn-deficiency-response elements (ZDREs) in a number of the ZIPs.

78 cin) for 6 or 12 weeks based on radiographic response followed by surgery and further chemotherapy de

79 are activated via a non-FcepsilonRI mediated response following silver nanoparticle (Ag NP) exposure,

80 to assist hospitals in establishing a rapid response for identification, notification, and evaluatio

81 essional phagocytic cells and subvert immune responses for chronic persistence in the host.

82 dentify whether they had different treatment responses from the pooled group.

83 period of participant's oscillatory impulse response function reverberating in alpha.

84 for each country, we estimate a common dose-response function, which we use to compute national elec

85 of targetable proteins associated with drug responses further identified corresponding synergistic o

86 IF2alpha, enabling the translation of stress response genes; among these is GADD34, the protein produ

87 ate in male liver generally showed early cGH responses; genes in an inactive chromatin state often re

88 n mice that would otherwise express stimulus-response habits.

89 ite this, the mechanism of the innate immune response has been less well studied, although it is key

90 h nodes (LNs), but how this affects adaptive responses has not been extensively studied.

91 increasing the regulatory arm of the immune response in animals models of autoimmunity and Th17-skew

92 g sufficient to consistently achieve durable response in MCL.

93 Here we show that the transcriptional response in neurons is exquisitely sensitive to the temp

94 s associated with a decreased humoral immune response in Rictor KO mice.

95 ions, and 936 and 220 genes involved in salt response in roots and leaves, respectively.

96 s create a "contagious" physiological stress response in the observer?

97 a pro-inflammatory and an immunosuppressive response in the skin.

98 icitation of broad and potent serum antibody responses in all four cows.

99 Importantly, prominent mucosal immune responses in CCR7-deficient mice increased the efficienc

100 sed on orthogonal polynomials showed similar responses in clinical parameters, inflammatory mediators

101 ccessful in the induction of NAbs and T cell responses in guinea pigs.

102 agnitude of MHC-B-restricted cellular immune responses in HIV-infected individuals.

103 ith thapsigargin prolonged NMDAR-DeltaCa(2+) responses in MNCs of sham rats, but this effect was occl

104 , but immunological tools to study anti-ZIKV responses in preclinical models, particularly T cell res

105 s capable of triggering neuroprotective Treg responses in synucleinopathy models, and the combined va

106 nic infection and stimulates vigorous immune responses in the human host; forcing selection of viral

107 r induction and maintenance of Th17 effector responses in the inflammatory contexts of both acute inf

108 an exceeding 30 years, and found that injury responses in this species are quite distinct from those

109 the appearance of transgene-specific T-cell responses in two subjects that were part of the phase II

110 iderations and experimental models of immune responses in vitro and in vivo to quantify the spatial e

111 y as assessed by their ability to inhibit Ab responses in vitro.

112 at Foxp3+ Tregs potently suppress autoimmune responses in vivo through inhibition of the autophagic m

113 ique to NS1 contribute to modulation of host responses, including inhibition of type I interferon res

114 rongly suppressive functions toward allergic responses induced by naive and in vivo-primed human T he

115 s in reward contingency, and OFC encoding of response information was strongly attenuated.

116 rk cycle suggests uncoupling of hypothalamic responses involving appetite-stimulating fasting-respons

117 BRAF inhibitors, we hypothesized therapeutic response is related to tumor metabolic phenotype, and th

118 f attentional task, although a subset of the responses is modulated similarly to prefrontal and parie

119 The multiple response issue was also carefully addressed.

120 significantly boosting the mucosal antibody response, it augmented the frequency of IFN-gamma secret

121 SLCs and less frequent, long-latency startle responses (LLCs).

122 gering of the mitochondrial unfolded protein response, loss of mitochondrial membrane potential and s

123 the type-B ARRs in regulating the cytokinin response, mechanism of type-B ARR activation, and basis

124 ill be defined as complete response, partial response, minor response, stable disease, or progressive

125 ontrol group) of Chinese children's Mismatch Responses (MMRs) to equivalent pitch deviations represen

126 We propose a treatment response model, fully parameterized with experimental im

127 rea), to "convergent" at long time where its response now tends toward that of a hemicylinder of equa

128 Our study sheds light on the nonlinear response of a circumpolar seabird to large-scale changes

129 ty and, consistent with that, potentiate the response of cells to the drug.

130 However, the differential response of human leukocytes to MPLA and LPS has not bee

131 We tested the response of mobile estuarine consumers over 5 months to

132 These differences in the response of periodontal tissues to orthodontic force in

133 Basin, YRB) were evaluated, determining the response of precipitation to external changes over typic

134 al limits by investigating the acute warming response of six Antarctic marine invertebrates: a crusta

135 e the concentration dependence of the ligand response of the rationally designed, artificial theophyl

136 d States in summer require understanding the response of this dynamical and photochemical system to i

137 Here we measured the responses of a marine diatom, Thalassiosira pseudonana,

138 p, we have developed a model to simulate the responses of all tactile fibers innervating the glabrous

139 stances; both the rhythm and neuromodulatory responses of breathing are controlled by brainstem neuro

140 Temperature responses of density varied intraseasonally in strength

141 genic crops, with each case representing the responses of one pest species in one country to one inse

142 he transcriptomes of reproductive and immune responses of the pistil makes it a prime system in which

143 " at very short time, where the amperometric responses of the supported microwire closely resemble th

144 the temporal differences seen in the immune responses of these mice.

145 We demonstrate the capability to resolve the responses of two genetically encoded Zn(2+) sensors at a

146 ce to assess independent effects of DEB-TACE response on recurrence.

147 ns, induce a recall CD4(+) TH1 proliferation response only in CMV-seropositive donors.

148 Overall response will be defined as complete response, partial response, minor response, stable disea

149 functional magnetic resonance imaging (fMRI) response patterns in the human auditory cortex.

150 ve screening approach where mRNA from PGE2-G response-positive and -negative cell lines was subjected

151 The hierarchy changed as the immune response progressed, and it was dependent on antigen for

152 urrent results reflect a substantially lower response rate (21% vs. 31% and 49%, respectively) and an

153 The overall response rate for patients with IMT (treated at 100, 165

154 516 patients achieved SVR, a response rate of 86% (95% CI, 83.0% to 88.7%), with no m

155 edotin is effective in treating LyP (overall response rate, 100%; complete response rate, 58%), but i

156 g LyP (overall response rate, 100%; complete response rate, 58%), but its use should be reserved for

157 gimen Selection), may significantly increase response rates for breast cancer patients, especially th

158 izes a complex between 14-3-3 and the stress response regulator GCN1, inducing GCN1 turnover and neur

159 ulation protein NT-NtrC, and the sporulation response regulator Spo0F.

160 ctive state of receiver domains of bacterial response regulators.

161 require general agreement on definitions of response, relapse, and methods of determining minimal re

162 The estimated exposure-response relationship for Vibrio infections at a thresho

163 ted cubic spline models to evaluate the dose-response relationships.

164 s in preclinical models, particularly T cell responses, remain sparse.

165 ated proteins in BR receptor dynamics and BR responses remains elusive.

166 To better probe the p53 response, SJSA cells (shCDK19 versus shCTRL) were treate

167 aracteristics are key to generate an in vivo response, specifically whether systemic drug exposure is

168 Complete and partial response, stable disease, and progressive disease were d

169 s complete response, partial response, minor response, stable disease, or progressive disease.

170 s in the presence of detectable inflammatory responses, suggesting the involvement of complex viral m

171 s, including inhibition of type I interferon responses, suppression of dendritic cell maturation and

172 Response surface experiments showed that a 10g/l liquid

173 regnation method, followed by application of response surface methodology to identify the optimal Pd-

174 The objectives of this study were to apply response surface methodology to optimize fat-soluble vit

175 ated patients 2:1 using an interactive voice-response system to eltrombopag or placebo, stratified by

176 domly assigned (1:1) by an interactive voice-response system to receive either oral lenalidomide (2.5

177 autoimmune disorders when an abnormal immune response targets normal biological components.

178 Finally, rDEN2Delta30 induced stronger CD8 responses than other, more attenuated DENV isolates.IMPO

179 hat K6a network remodeling is a host defense response that directly up-regulates production of kerati

180 optomotor course correction to optic flow, a response that is dependent on the spatial structure of t

181 nditions, and observe a subharmonic temporal response that is robust to external perturbations.

182 n coincides with the ATM-mediated DNA damage response that occurs on functional telomeres following r

183 ing apoptosis, DNA repair and early estrogen response that were differentially regulated between WT,

184 epression, which is followed by steady-state responses that are frequency invariant for their physiol

185 The immune and autoimmune responses that characterize IgAN indicate a potential be

186 d detectable Dengue cross-reactive serum IgG responses that significantly amplified after Dengue-2 vi

187 the way attention alters the early cortical responses that support selective information processing.

188 ycoproteins induce a strong innate antiviral response through activating the ER stress pathway during

189 murine macrophages, regulating innate immune responses through the initiation of a type I IFN-depende

190 cells in controlling the TFH-germinal center response to a cholesterol-rich diet and uncover a PDL1-d

191 , the range of global warming projections in response to a doubling of CO2-from 1.5 degrees C to 4.5

192 phenotypes of breast cancer cells adopted in response to a nutrient-deficient microenvironment.

193 or high changes in cardiac repolarization in response to a pharmacological challenge with sotalol.

194 Expansion of adipose tissue in response to a positive energy balance underlies obesity

195 d sex interact to affect the transcriptome's response to a stressor.Animals' response to acute stress

196 carbohydrate fermentation or inflammation in response to accumulated plaque select for a cariogenic o

197 exhibited increased locomotor activation in response to acute cocaine administration and an altered

198 nscriptome's response to a stressor.Animals' response to acute stress is known to be influenced by se

199 enes were considered potential predictors of response to ADI-PEG20.

200 rotein complexes regulate the Rag GTPases in response to amino acids, including GATOR1, a GTPase acti

201 inducible factor (HIF)-1alpha and -2alpha in response to angiotensin II and hypoxia, respectively, wh

202 ive analyses of adult patients with AML, the response to Ara-C-containing therapy was inversely corre

203 quency in the circulation is a new marker of response to ART when effects on viremia and clinical res

204 TF4 serve complementary roles in the hepatic response to asparaginase.

205 monocytes with less proinflammatory cytokine response to bacterial stimulation and less human leukocy

206 cularly powerful endophenotypic predictor of response to BATD in MDD.

207 ria by opening a large, water-filled pore in response to changes in membrane tension.

208 and the expression was further increased in response to cisplatin.

209 composition, tumour-to-tumour heterogeneity, response to colony-stimulating factor 1 receptor (CSF-1R

210 The opal5 mutant does not close in response to darkness but exhibits wild-type (WT) behavio

211 ntial to accurately modeling yeast growth in response to different environments.

212 nocytes showed increased metabolic stress in response to DSS with higher levels of phospho-AMPK and l

213 ce on stimulation with HGF, but had the same response to EGF.

214 g 16 crop models in predicting rice yield in response to elevated [CO2] (E-[CO2]) by comparison to fr

215 egral part of the hypothalamic engagement in response to elevated circulating E2 Collectively, we wil

216 siesta onset, but not night sleep onset, in response to elevated temperatures.

217 FICANCE STATEMENT Animals adjust behavior in response to environmental changes, such as fluctuations

218 features that may be predictive of clinical response to epigenetic therapy.

219 here that mTORC1 and mTORC2 are activated in response to exogenously supplied fatty acids via the de

220 In response to extracellular matrix signalling, these cells

221 the left dHb-IPN pathway in attenuating the response to fear.

222 RNA motifs that regulate gene expression in response to fluctuating metabolite concentrations.

223 rangement of the macromolecular structure in response to force.

224 em with this therapy is the patient's immune response to FVIII, because of a lack of tolerance, leadi

225 transcripts and metabolites were changed in response to genotype, and cell wall composition was larg

226 ial pressure, renal function, and the reflex response to hemorrhage in sheep with normotension (contr

227 n synthesis, and increased autophagy flux in response to hyperammonemia, which were partially reverse

228 tations such as CARD11 may have an impact on response to ibrutinib, may inform clinical decisions, an

229 soforms of miRNAs (isomiRs) to the miRISC in response to IL-1beta, including miR-146a-5p, miR-155-5p

230 and PEA (P < 0.001-0.001) were increased in response to inflammatory mediators.

231 tudy its dynamics at multiple time scales in response to inputs approximating real spatiotemporal pat

232 and reduced leukocyte cytokine secretion in response to lipopolysaccharide stimulation.

233 Recovery of cardiac function in response to mechanical unloading was assessed by echocar

234 tream of NRT1.1 and independently of NLP7 in response to nitrate.

235 Yet reefs are degrading rapidly in response to numerous anthropogenic drivers.

236 roposed that thalamic bursts are an adaptive response to pain that de-synchronizes cortical theta and

237 we report a reduction in atherosclerosis in response to pharmacological stimulation of thermogenesis

238 n actin cap to resist nuclear deformation in response to physiological mechanical stresses.

239 s (miRs) in rectal cancer that would predict response to radiation and identify target pathways that

240 expected from a substance to be released in response to RIPC and to protect the myocardium during is

241 a correlation between age at disease onset, response to sodium channel blockers and the functional p

242 s and pathways that orchestrate the cellular response to ssUVR.

243 serve the pH conditions inside glycosomes in response to starvation conditions.

244 ition to a slow-cycling, persistent state in response to targeted kinase inhibitors.

245 Vaccinated volunteers had an immunodominant response to the Gag293 epitope with a functional avidity

246 ses a range of pro-inflammatory cytokines in response to the infectious challenge.

247 we suggest that the directed movements are a response to the physical arrangement of the polymers in

248 btherapeutic concentrations is increasing in response to the rising demand for food animal products w

249 In response to this rising threat, a highly efficient, envi

250 er to determine the impact of the epigenetic response to traumatic stress on post-traumatic stress di

251 l cure on culture is a predictor of clinical response to treatment.

252 of cough frequency throughout the day and in response to tuberculosis therapy.

253 ine the propensity of acquiring mutations in response to vaccine or treatment with one or a cocktail

254 nfection (hpi), suggesting a unique neuronal response to viral infection.

255 lprotectin levels were linked to therapeutic responses to antibiotics.

256 aspects of growth and development as well as responses to biotic and abiotic factors.

257 tion into systems with complex, programmable responses to different sets of stimuli.

258 cture permits stable and replicable ensemble responses to diverse sensory stimuli under various exter

259 ss may be beneficial if it enhances adaptive responses to ecological stressors in the shared environm

260 s had little impact on field-estimated trait responses to elevation.

261 Treeline responses to environmental changes describe an important

262 amine interindividual variability in skin MC responses to FcepsilonRI triggering vs those evoked by M

263 ere as decreased SST expression, may disrupt responses to fear and anxiety regulation in these indivi

264 We conclude that root tropic responses to gravity and water are driven by distinct ti

265 Consequently, species' responses to habitat destruction vary as other species b

266 Analysis of hypothalamic and neuroendocrine responses to HFS throughout the light-dark cycle suggest

267 abolic pathways and more dramatic glycolytic responses to hormonal stimulation.

268 nvestigated the role of Act1 in keratinocyte responses to IL-17 using a tetracycline inducible short

269 trast, early visual areas generally manifest responses to individual stimuli and to their interaction

270 es were simulated to characterize metabolite responses to ischemia.

271 lymphocyte numbers, and normal proliferative responses to mitogens.

272 ne alloys, MGs have some specific structural responses to neutron irradiation.

273 le with other techniques, such as behavioral responses to pharmacological manipulations and spike tim

274 er decreases Nrf2 function and antioxidative responses to S Typhimurium infection, eventually leading

275 In vivo, promoter responses to TAF mutations correlate with the level of d

276 xt-dependent information to calibrate growth responses to temperature signals.

277 or immunity to a scaffold may inhibit immune responses to the antigen-scaffold combination.

278 ed significantly heightened skin conductance responses to the CS without shock during fear conditioni

279 ve responses toward more adaptive behavioral responses to threatening stimuli.

280 It then is important to monitor responses to treatment, to quickly identify those therap

281 a shift from expression of innate defensive responses toward more adaptive behavioral responses to t

282 activity of this fragment by promoting serum response transcription factor binding to a cryptic cis-e

283 ession of genes involved in oxidative stress responses, tumor progression and chemoresistance.

284 SAgs) that provoke a swift hyperinflammatory response typified by a cytokine storm.

285 veals the dynamic process of gNP aggregation responses upon biomolecular binding.

286 noise correlations, associated with neuronal response variability.

287 Time to response was 3 weeks in all patients.

288 The precision of the fold-change response was observed throughout the signaling duration

289 gnitudes of the gp120- and V1V2-specific IgG responses were comparable between adults and infants imm

290 Allergic airways responses were measured 48 h after the last challenge.

291 Strikingly, similar responses were observed in allergic patients and beekeep

292 d generation of an effective anti-WNV immune response when Tregs lacked MAVS, thereby demonstrating t

293 of gp96 primes T helper type 1 (Th1) immune responses, whereas high-dose immunization primes respons

294 gating mechanisms of mutation-dependent drug response, which will have a significant impact on cancer

295 K)2 downregulates the proinflammatory T cell response while increasing the regulatory arm of the immu

296 Overall response will be defined as complete response, partial r

297 However, identifying distinct responses will enable novel routes for PTP-selective dru

298 n healthy Thai adults and its priming immune responses with an H5N1 inactivated vaccine boost.

299 aling pathways to coordinate cellular stress responses with sterol homeostasis.

300 individual patients had different levels of responses within the M1 and M2 clones.