ライフサイエンスコーパス: responsible

1 identified biallelic mutations of PRUNE1 as responsible.

2 ests feedback instability (loop gain > 1) is responsible.

3 ut can be accomplished under environmentally responsible conditions, are discussed as representative

4 tle interplay between these three factors is responsible for (i) the formation of non-IPR (isolated p

5 Scabies was responsible for 0.21% of DALYs from all conditions studi

6 on with a median delay of 50 months and were responsible for 5 deaths.

7 s to food resources, we found that ants were responsible for 52% of total bait removal whilst vertebr

8 7%), while for deeper regions arterioles are responsible for 61% of the total pressure drop.

9 Gram-positive bacteria were responsible for a high proportion of infections among ch

10 al to the heterojunction and find that it is responsible for a large interfacial nonlinearity probed

11 h increased intrinsic noise is thought to be responsible for a range of perceptual deficits in amblyo

12 The structural motifs responsible for activation and regulation of eukaryotic

13 een linked to many of the biological changes responsible for adverse left ventricular remodeling, the

14 reviously identified a bacterial gene (arsI) responsible for aerobic demethylation of methylarsenite

15 opoietic expression of TREM2 was found to be responsible for aggravated hepatitis, indicating a novel

16 he interaction with FcepsilonRI is primarily responsible for allergic sensitization and the inflammat

17 mise for modulating multiple immune pathways responsible for allograft injury and loss.

18 of the Nkx3.1 transcription start site to be responsible for alterations in Nkx3.1 expression pattern

19 0 (K10) resulting from Cdk5 knockdown may be responsible for an abnormal epidermal structure.

20 of degranulation markers, were specifically responsible for arginase 1 activity.

21 Tropical deforestation is responsible for around one tenth of total anthropogenic

22 Cellular and molecular mechanisms responsible for ASD pathogenesis have been proposed base

23 The maturation protein is responsible for attaching the virus to an F-pilus and de

24 the structure of the HCV envelope, which is responsible for attachment and fusion, could aid in the

25 s) phenotypic switch, one of the main events responsible for bare metal in-stent restenosis after per

26 Histone chaperones are responsible for binding the highly basic histone protein

27 Mitochondria are responsible for bioenergetics, metabolism and apoptosis

28 sting selection of specific alleles of genes responsible for biological processes common to angiosper

29 r structural characterization of the enzymes responsible for biomineralization.

30 flavones such as chrysin and apigenin and is responsible for biosynthesis of baicalein and scutellare

31 Thus Gli1 marks mesenchymal progenitors responsible for both normal bone formation and fracture

32 nal subunit of the Rad3-Rad26 complex and is responsible for bringing the kinase to sites of DNA dama

33 to predict the detailed atomistic mechanisms responsible for C1 and C2 products on Cu.

34 Gillnets had a lower impact, but were still responsible for ca. 9% of juvenile mortality on shags, w

35 n of currently unmeasurable protein isoforms responsible for cancer progression.

36 The NLRP3 inflammasome is a protein complex responsible for caspase-1-dependent maturation of the pr

37 Furthermore, base excision repair (BER) is responsible for causing CAG repeat contractions downstre

38 Islet amyloid polypeptide (IAPP) is responsible for cell depletion in the pancreatic islets

39 n double strand break repair and is uniquely responsible for cellular sensitivity to poly(ADP-ribose)

40 iimine)Ni(R)(C2H4)(+) complexes, the species responsible for chain growth.

41 has focused in particular on the mechanisms responsible for change in frequency and attributes of cu

42 possible rearrangements of TMHs within them responsible for channel gating, we perform cross-linking

43 Group B coxsackieviruses are responsible for chronic cardiac infections.

44 a demonstrate that the pathogenic mechanisms responsible for chronic inflammatory demyelination polyn

45 is the most abundant enzyme in plants and is responsible for CO2 fixation during photosynthesis.

46 However, the mechanisms responsible for collective behaviour in mosquitoes are n

47 f the Cas9 catalytic domains (HNH and RuvC), responsible for concerted cleavage of the two DNA strand

48 nreducing polyketide synthases (NR-PKSs) are responsible for controlling the aldol cyclizations of po

49 al and milk production, as this community is responsible for converting plant-based feeds into access

50 no acid mutation in VP1, which is the enzyme responsible for copying the viral RNA genome.

51 erways, lakes, and coastal marine beaches is responsible for costs that should be accounted for when

52 the mitotic spindle is a fundamental process responsible for creating sibling cell size asymmetry; ho

53 tions occur when a surgeon is simultaneously responsible for critical portions of 2 or more operation

54 ne-knot proteins (burs alpha and burs beta), responsible for cuticle tanning and other developmental

55 ure is documented, the underlying mechanisms responsible for dark-induced cytoskeletal arrangement re

56 OPCs; PDGFRalpha+) produced oligodendrocytes responsible for de novo ensheathment of approximately 30

57 the understanding of mechanisms that may be responsible for defective skin repair.

58 phosphatase and tensin homolog) as primarily responsible for defects in B lymphocyte migration and an

59 V) serotypes are mosquito-borne flaviviruses responsible for dengue fever and dengue hemorrhagic feve

60 the tubulin tyrosine carboxypeptidase (TCP) responsible for detyrosination has remained unclear.

61 estigations on molecular events and pathways responsible for developmental toxicity have been largely

62 vation of the levels of TET enzyme, which is responsible for DNA demethylation in UVB-exposed skin.

63 trigger, a subinterval of magmatism must be responsible for driving deleterious environmental effect

64 hans cells, delineate the signaling pathways responsible for each phase of the hair cycle, or elucida

65 that secrete IL-17A, but not IFN-gamma, was responsible for early IL-17A production.

66 id surface and in internal networks that are responsible for EC stability.

67 uscle catabolism by activating TLR4, and are responsible for elevation of circulating cytokines.

68 ositive slow recycling pathway, which may be responsible for ensuring a persistent pool of GPRC6A rec

69 es severe hemorrhagic fever in humans and is responsible for epidemics throughout sub-Saharan, centra

70 sculus, we analyzed the signaling components responsible for epithelial stem cell proliferation.

71 ed virulence factors include secreted toxins responsible for extensive damage to host tissues and eva

72 with powerful enzymatic back-up systems, are responsible for fine-tuning physiological redox signalin

73 However, the molecular mechanism responsible for flow-induced beneficial effects is incom

74 Piezo1 is responsible for flow-sensitive non-inactivating non-sele

75 The molecular mechanisms responsible for flower sex specification remain unclear

76 In particular, the structure(s) responsible for force generation during meiotic chromoso

77 The major current responsible for frequency-dependent reduction of overall

78 However, the channels responsible for generating electrical signals downstream

79 CAF-1 subunits, and mapped the CAF-1 domains responsible for H3-H4 binding.

80 The prefrontal cortex is responsible for higher order cognitive processing, and p

81 xtractions with Cellulase and Viscozyme were responsible for highest extraction yields (67-77%).

82 mics, leading to a metabolic infection state responsible for highly penetrant male-restricted hepatic

83 ly factor 1 (CAF-1) is the histone chaperone responsible for histone (H3-H4)2 deposition following DN

84 Mechanistically, HDAC3 activity is largely responsible for histone deacetylation and inflammatory r

85 sive complex 1 (PRC1), the E3 ligase complex responsible for histone H2A ubiquitination and gene sile

86 Transient symptomatic episodes of AF, often responsible for impaired quality of life, are unpredicta

87 ions showing that the osteoid matrix that is responsible for implant osseointegration originates from

88 s been shown that chaperones or karyopherins responsible for import can maintain the stability of rib

89 ein 60, was identified as one of the factors responsible for inducing the expression of PTX3 in host

90 ed from a strong base and DMSO (solvent), is responsible for inducing the initiation by a photo-BHAS

91 By assessing the signals responsible for induction of the Notch ligand delta-like

92 anscriptional interference mechanism that is responsible for inhibiting expression of the coding NDC8

93 CYP450 is not the sole intracellular enzyme responsible for intracellular transformation.

94 long-range non-electrostatic interaction are responsible for intrafibrillar mineralization.

95 coral mortality worldwide; however, factors responsible for intraspecific variation in disease resis

96 plex as the metabolite of disulfiram that is responsible for its anti-cancer effects, and provide met

97 ections to antifungal treatment and could be responsible for its high dissemination rates.

98 ategically positioned amino acids are mainly responsible for its substrate specificity.

99 ulated in HNSCC-associated CAFs, where it is responsible for key pathogenic contributions in this dis

100 in mouse retina forms the synaptic mechanism responsible for long-range coherent activity in the reti

101 we hypothesized that reduced Zhx2 levels are responsible for lower Mup expression in BALB/cJ mice.

102 Borrelia burgdorferi, the bacterial pathogen responsible for Lyme disease, modulates its gene express

103 e for linker O-glycans, namely that they are responsible for maintaining separation between ordered d

104 vade new erythrocytes perpetuating the cycle responsible for malaria.

105 Carotenoid pigments are responsible for many of the red, orange, and yellow colo

106 nd that the ubiquitin/proteasome pathway was responsible for MeCP2 T158M degradation and that proteas

107 Instead, beta2 adrenoceptor activation was responsible for mediating gene silencing of IL-27p28 and

108 otection; however, the innate effector cells responsible for mediating this protection remain largely

109 3 and Staphylococcus aureus PBP 2A, which is responsible for methicillin resistance.

110 Polycomb repressive complex 2 (PRC2) is responsible for methylation of histone H3 lysine 27 (H3K

111 Chlamydia is responsible for millions of new infections annually, and

112 and its use, in the form of ALARA dosing, is responsible for misguided concerns promoting radiophobia

113 al stem cells (aNSCs), and Tet2 is primarily responsible for modulating 5hmC dynamics.

114 mediators and the exact chemical mechanisms responsible for modulating myocardial mPTP opening remai

115 ned within the 530 bp deletion that could be responsible for modulation of leukotoxin production have

116 In general, causes of death responsible for more YLLs overall also contributed more

117 Metastasis is responsible for most cancer-related deaths, but the curr

118 metastases occur in half of patients and are responsible for most cancer-related deaths.

119 and four PDZ domains, with the latter being responsible for most of Scribble's complex formation wit

120 In the lung, ENaC is responsible for movement of sodium.

121 Site diffusion is responsible for multilayer growth in the linear and into

122 ealed that the 2-methylimidazolate ligand is responsible for multiple redox transformations.

123 l population of fetal-derived hematopoiesis, responsible for natural Ab production and rapid immune r

124 Whether cPLA2alpha is directly responsible for neutrophil synthesis of LTB4 in the cont

125 hy to identify central and peripheral nerves responsible for nociception and sensitization of the def

126 dy elucidates a pivotal regulatory mechanism responsible for normal nuclear structure and which is ex

127 ) is a commonly occurring foodborne pathogen responsible for numerous multistate outbreaks in the Uni

128 r of the model, and to help identify factors responsible for observed patterns of infections.

129 lament, known as the presynaptic complex, is responsible for pairing the ssDNA with homologous double

130 Identification of specific immune responses responsible for pathogen protection enables vaccine deve

131 The biotin pathway genes responsible for pimelate moiety synthesis vary widely am

132 ic target to normalize metabolic aberrations responsible for poor prognosis in ovarian cancer.

133 (-) serves as the persistent radical that is responsible for predominant cross-coupling.

134 However, while the subcortical circuitry responsible for processing and expression of fear has be

135 h many diseases of aging, but the mechanisms responsible for producing this inflammation remain uncle

136 el and indicate that the same interaction is responsible for promoting integration and for inhibiting

137 chine composed of RNA and proteins and it is responsible for protein synthesis.

138 The mechanisms responsible for RdDM are guided to target loci by small

139 rved organelle housing specialized molecules responsible for receiving and processing extracellular s

140 tropic ERVs differentially alter the regions responsible for receptor determination or subject to APO

141 d short-wavelength sensitive (S)-opsins, are responsible for red, green and blue color recognition, r

142 igament mesenchymal stem cells (PDLMSCs) are responsible for regeneration of the periodontium that is

143 One well-characterized protein responsible for regulating both response to drugs and ge

144 he Apicomplexan AP2 (ApiAP2) family, that is responsible for regulating the expression of genes invol

145 major E3 ubiquitin ligases from human cells responsible for regulation of NEIL1 by ubiquitylation.

146 species, Siganus virgatus, was almost solely responsible for removing S. ilicifolium biomass, account

147 r (NSS) family of membrane proteins that are responsible for reuptake of neurotransmitters from the s

148 and STACHYOSE SYNTHASE (STS) are the enzymes responsible for RFO biosynthesis in plants.

149 f fecal indicator bacteria (FIB, a pollutant responsible for runoff-associated inland and coastal bea

150 ns should also reinstate the neural activity responsible for semantic processing.

151 oli O157:H7 is an enterohemorrhagic bacteria responsible for serious foodborne outbreaks that causes

152 Variations in the ABCB4 gene are responsible for several biliary diseases, including prog

153 by enhanced formation of arterioles, may be responsible for shift of Hmox1(-/-) myofiber size distri

154 that BeauIII binds to a putative active site responsible for SOAT1 that is located on the cytosolic s

155 IL-10 is responsible for STAT3 activation during the first round

156 However, the mechanisms responsible for such adaptive homeostasis remain largely

157 NK cells were responsible for such attenuated responses because deplet

158 (HGF) required for the chemotactic gradient responsible for sustained directionality.

159 Aromatase is the enzyme responsible for synthesis of E2 from androgens.

160 The enoyl reductase InhA, responsible for synthesis of essential mycolic acids in

161 pends on primase, the specialised polymerase responsible for synthesis of the RNA primers that are el

162 lead to the exposure of hydrophobic regions responsible for target protein recognition.

163 s (NRPSs) comprise giant multidomain enzymes responsible for the "assembly line" biosynthesis of many

164 The activation of this pathway was responsible for the accumulation of tau oligomers after

165 interrogated to identify molecular features responsible for the activity, which can in turn yield si

166 of the inner and outer nuclear membrane are responsible for the additional fluctuation process, as s

167 rather than allosteric modulation, could be responsible for the adverse effects.

168 Decreased peak ICa-L was found to be responsible for the age-associated increase in SR Ca con

169 ajor antigenic site of HA was reported to be responsible for the antigenic drift.

170 t this synergistic interaction may be mostly responsible for the antioxidant activity that was observ

171 uisite for developmental programs ultimately responsible for the appropriate long-range AMPAR-mediate

172 The intense interest in the mechanisms responsible for the beneficial effects of breast-feeding

173 His96 is responsible for the binding of two haem groups within th

174 s a conserved multicomponent protein complex responsible for the biogenesis of beta-barrel outer memb

175 The polyketide synthases responsible for the biosynthesis of the polyether antibi

176 probe the electronic structure and orbitals responsible for the bonding interactions in the Sc-OCPPC

177 ) is a nucleotide pool "housekeeping" enzyme responsible for the catabolism of canonical and noncanon

178 o different intermediates were identified as responsible for the change in selectivity of the heterog

179 ere isolated and identified as the compounds responsible for the characteristic odor of lion MF.

180 tibiotics as if they were the sole mechanism responsible for the clearance of infections.

181 We find that the Cu(II) moieties responsible for the conversion are formed in the presenc

182 ystal surfaces and nanocrystal core size are responsible for the crystallization process.

183 Diarrhea is responsible for the death of approximately 900,000 child

184 ction of the cell cycle inhibitor Cdkn1a was responsible for the decreased proliferation in the knock

185 GLO1 is a ubiquitous cellular enzyme responsible for the detoxification of the glycolytic byp

186 ons traveling within the brachial plexus are responsible for the dexterous control of human arm and h

187 Vibrio cholerae is responsible for the diarrheal disease cholera that infec

188 DNA-repair mechanisms are at least partially responsible for the different evolutionary outcomes obse

189 hereas the activation of GABAA receptors was responsible for the direct inhibition of light-evoked sp

190 riven by the very same pathogenic mechanisms responsible for the disease, the autoimmune attack on th

191 rger ones and their settling are potentially responsible for the distinct color change observed.

192 ted with pKa of the functionalized ligand as responsible for the dramatic selectivity changes.

193 work, we focused on the fundamental insights responsible for the electronic properties of three disti

194 row (BM) Gr-1(lo) immature myeloid cells are responsible for the elevated, pathological levels of suP

195 it remains unclear what mechanisms could be responsible for the elicitation of particle and ion rele

196 The factors responsible for the emergence of pathogenic ZIKV are not

197 However, the types of cells and molecules responsible for the engulfment of dead cells in the infa

198 which is known to be the structural feature responsible for the enhancement.

199 and STAT3 are the key transcription factors responsible for the expansion and differentiation of hum

200 The centromere is the structural unit responsible for the faithful segregation of chromosomes.

201 which secrete extracellular matrix proteins responsible for the fibrotic scar.

202 ferase 1 (EPT1) gene (now known as SELENOI), responsible for the final step in Kennedy pathway formin

203 uently accelerates contact activation and is responsible for the full procoagulant activity of FXII.

204 molecule(s) on the endothelial cell surface responsible for the galectin-3-mediated cytokine secreti

205 ts to cultured neurons suggested that C3b is responsible for the growth inhibitory and neurotoxic or

206 trate that the up-regulation of the ALOX5 is responsible for the Hcy-dependent worsening of the AD ph

207 frequent homologous recombination, is likely responsible for the high diversity of T6SS effector-immu

208 piration and root allocation parameters were responsible for the highest fraction of predictive uncer

209 Capsaicinoids are responsible for the hot taste of chili peppers.

210 ures to environmental factors are considered responsible for the increasing prevalence of allergic di

211 ites (HDM) may serve as carriers of bacteria responsible for the induction of IgE sensitization to mi

212 of circulating monocytes into the joint are responsible for the initial reduction of macrophages fol

213 local (within field) inoculum sources may be responsible for the initiation of CLS epidemics in mixed

214 identified the residues within RRM1 and RRM2 responsible for the interaction between DHTS and HuR.

215 h in basic residues at the C-terminal end is responsible for the interaction with RNA polymerase.

216 Epithelial cadherin (Ecadherin) is responsible for the intercellular cohesion of epithelial

217 ted by myosin light chain kinase (MLCK) were responsible for the intriguing turning behavior of T cel

218 e GCN4/SKn1/RY motif is not the only element responsible for the level of PAPhy_a expression during g

219 TACE is a major shedding protease, responsible for the liberation of the inflammatory cytok

220 ggest the SR as the primary source of Ca(2+) responsible for the loss of the Ca(2+) transient upon in

221 equences of the lymphotropic HCV strain were responsible for the lymphotropism.

222 ellular glutamate in the NAc, while GLT-1 is responsible for the majority of glutamate uptake.

223 individuals infected with clade C, which is responsible for the majority of HIV infections worldwide

224 f protein and amino acid metabolism as it is responsible for the majority of proteins secreted in the

225 on between the Cu(+) and Cu(0) surface sites responsible for the MEOM mechanism suggests a unique str

226 ngliosidosis, indicating that this enzyme is responsible for the metabolic bypass of beta-hexosaminid

227 dence that the silicon based 2D overlayer is responsible for the observed linear dispersed feature in

228 t the point mutation C64T in the TYR gene is responsible for the OCA1 albino phenotype in the capuchi

229 n intermediate state which is believed to be responsible for the onset of the aggregation process lea

230 e deformations that are suggested to also be responsible for the optical modulation of naturally occu

231 s produced by the mature female parasite are responsible for the pathogenesis and transmission of sch

232 However, the specific IFN regulated proteins responsible for the pathogenic effects of ADAR1 mutation

233 The proposal that reduced reticulon-1 is responsible for the poor inherent ability of macrophages

234 To better understand the mechanisms responsible for the ppDIO-induced alterations in sleep,

235 that English Thoroughbred sires are largely responsible for the predominance of this haplotype in mo

236 hat the different PBDs of lipins 1 and 3 are responsible for the presence of phosphoregulation on the

237 We also show that commendamide is responsible for the previously described hemolytic activ

238 These neutrophils were responsible for the pro-metastatic effect of MSCs since

239 , as we cannot exclude that this lineage was responsible for the production of Acheulean or Middle St

240 trait locus (QTL) that harbours the FGR gene responsible for the production of GABA.

241 However, the identity of the ex-RNA responsible for the proinflammatory effect remains uncle

242 es, has gained attention as a possible agent responsible for the purported health benefits of certain

243 tabolism components; however, which ones are responsible for the quantitative variation found in resp

244 nucleophilic aryl substitution mechanism was responsible for the rapid reaction of the faster substra

245 ermine the precise molecular-events sequence responsible for the rapid spine formation.

246 blation or inhibition of CYP27A1, the enzyme responsible for the rate-limiting step in 27-hydroxychol

247 The Asian lineage of ZIKV was responsible for the recent epidemics in the Americas.

248 Cu(2+) is responsible for the reduction in antioxidants and pertur

249 of a COI1-JAZ2-MYC2,3,4-ANAC19,55,72 module responsible for the regulation of stomatal aperture that

250 The viral protein E2 is responsible for the replication of the virus.

251 triggering arthritis are well defined, those responsible for the resolution of inflammation are incom

252 ty and the magnitude of myocardial injury is responsible for the resolving and nonresolving pathway i

253 By screening for the hydrolase that is responsible for the reversal of Ser-ADPr, we identified

254 between particles and colloids: OC + BC were responsible for the sorption of 65% of PBDEs, followed b

255 The lowest energy pipi* state is responsible for the sub-picosecond lifetime observed for

256 tion of regulatory cells, which are directly responsible for the suppression of CNS-damaging autoreac

257 We identify a functional EptA ortholog responsible for the transfer of the amino-residue phosph

258 s loosely bound aggregates or "flocs" and is responsible for the transport and fate of sediment, carb

259 G) in the N-terminal region of eIF2Bbeta was responsible for the TuMV resistance.

260 s suggest that small polaron localization is responsible for the ultrafast trapping of photoexcited c

261 AS for leaf color detects six candidate loci responsible for the variation of anthocyanins in lettuce

262 It is the existence of such modes which is responsible for the wonderful properties of a topologica

263 noids, and terpenoids, which are most likely responsible for their biological activity.

264 he tendency to hold the patient with obesity responsible for their condition can be a barrier to grea

265 nvironments they inhabited and the processes responsible for their preservation.

266 candidates constituting key structural units responsible for their pronounced therapeutic activities.

267 se acetophenones and transcripts of the gene responsible for their release is highly heritable and th

268 nd evening oscillators (E cells)-are largely responsible for these activity bursts.

269 panying frontal hyperactivation appear to be responsible for these alterations.

270 lations and defines the molecular mechanisms responsible for these differences.

271 We identify a key R146A residue that is responsible for these effects, and mutant CrPV(R146A) vi

272 However, to discern the molecular mechanisms responsible for this action, pigment regeneration with t

273 extracellular loop domain (E2) is primarily responsible for this adhesive function.

274 The downstream neural network responsible for this behavior and a potential role for g

275 The genetic determinants responsible for this canonical case of virulence evoluti

276 essor in others, and the molecular mechanism responsible for this cell-type specific function remains

277 nation and polyglutamination on TBA-7 may be responsible for this destabilization.

278 Although the ZEBOV variant responsible for this epidemic (Makona) shares significan

279 reasing, little is known about the hospitals responsible for this growth.

280 ownstream of OX40L/OX40 interaction in Tregs responsible for this novel mechanism are not understood.

281 exhibit reduced chemotaxis, but the targets responsible for this phenotype remain unknown.

282 tumor spread; however, the instructive cues responsible for this unique tropism were previously unkn

283 ese encephalitis virus (JEV) is a Flavivirus responsible for thousands of deaths every year for which

284 rt that downregulation of STAT3 signaling is responsible for TLR7-mediated inhibition of Th17 cells d

285 hia coli CusCFBA is a complex efflux system, responsible for transferring Cu(I) and Ag(I) ions; this

286 However, the molecular mechanisms responsible for transforming a normal brain into an epil

287 ne formed between PLP and GABA is apparently responsible for triggering the GabR-mediated transcripti

288 MT) is the murine polyomavirus oncogene most responsible for tumor formation.

289 migration, invasion and metastasis, but less responsible for Twist1-induced mesenchymal morphogenesis

290 encing effect on Foxa1 expression is largely responsible for Twist1-induced migration, invasion and m

291 The protein complex responsible for type IV pilus assembly is homologous wit

292 two-component system, named UzcRS, which is responsible for U-dependent activation of PurcA .

293 of immunoglobulin-related receptors that are responsible for various aspects of T-cell immune regulat

294 n the interactome of Xist, the noncoding RNA responsible for X inactivation.

295 ton and collaborators, we show that socially responsible gene drives require 0.5 < s < 0.697, a rathe

296 osity nor a reduction in soluble calcium was responsible, leading to the conclusion that in addition

297 oint mutations with the highest chance to be responsible of resistance to a particular targeted cance

298 the most important plant pigments, which are responsible of the intense red color of the calyces, and

299 receptors gate channels with slow kinetics, responsible primarily for generating long-term synaptic

300 data are needed to inform next steps in the responsible stewardship of this process, from the perspe