ライフサイエンスコーパス: responsible gene

1 ntify the transcription factor, Usf1, as the responsible gene.

2 oth muscle myosin heavy chain (myh11) as the responsible gene.

3 starting point for the identification of the responsible gene.

4 etic form of polymicrogyria and localize the responsible gene.

5 serves as a basis for the identification of responsible genes.

6 CTG.CAG, CGG.CCG, or AAG.CTT) in or near the responsible genes.

7 o the discovery of two of the four (or more) responsible genes.

8 The responsible gene acts as a tumor suppressor, and tumors

9 RMD locus set the stage for isolation of the responsible gene and elucidation of a novel patho-mechan

10 ess robust in identifying and validating the responsible gene and/or genetic variants.

11 an arise through several mechanisms, but the responsible genes and pathways are poorly understood.

12 The discovery of additional responsible genes and the elucidation of the molecular m

13 w are researchers beginning to tease out the responsible genes and the underlying molecular mechanism

14 disease loci may help identification of the responsible genes, and is thus a topic of considerable p

15 We provide evidence that the responsible gene at LGS1 codes for an enzyme annotated a

16 In none of these entities has the responsible gene been isolated; hence, the possibility t

17 d function, yet in only a few cases have the responsible genes been cloned.

18 es between these strains and to map a single responsible gene (called Ltx1) to chromosome 11.

19 We hypothesize that the responsible gene causes cortical hyperexcitability that

20 A study was undertaken to identify the responsible gene defect underlying late onset spinal mot

21 uch deficits is largely unknown, many of the responsible gene defects have been identified.

22 ton and collaborators, we show that socially responsible gene drives require 0.5 < s < 0.697, a rathe

23 The responsible gene, encoding methyl-CpG binding protein 2

24 nts defective in IT formation and cloned the responsible gene, ERN1, encoding an AP2/ERF transcriptio

25 Identification of the responsible gene for SCA26 ataxia will provide further i

26 n sequencing method, we excluded CASK as the responsible gene for the remaining family.

27 Myosin VIIa has been identified as the responsible gene for USH type 1B, and a number of missen

28 Expression analysis of the main responsible genes for Na(+) compartmentalization (i.e. N

29 1, has been mapped to chromosome 13, but the responsible gene has not been identified.

30 1, has been mapped to chromosome 11, but the responsible gene has not been identified.

31 tiple endocrine neoplasia type I because the responsible gene has not yet been isolated.

32 ent cause of ADPHSP in UK families, that the responsible gene has not yet been mapped in a significan

33 e is well established; identification of the responsible genes has proved challenging.

34 is absent from humans and disruption of the responsible genes has shown a lethal phenotype for Esche

35 from primary cilia of kidney cells, but the responsible genes have not been identified.

36 None of the 'responsible' genes have previously been identified.

37 risk and genetic mapping has identified the responsible gene in a few mendelian cases.

38 markers D16S419 and D16S400, localizing the responsible gene in this family to a 15 centimorgan regi

39 d to three loci: 2p21 (GLC3A), for which the responsible gene is CYP1B1, and 1p36 (GLC3B) and 14q24 (

40 was not identified, implying either that the responsible gene is essential for cell viability, or tha

41 The responsible gene is the human minibrain gene, and the ho

42 The identification of the responsible genes is providing scientists a window into

43 esterolemia were ruled out by sequencing the responsible genes (LDLRAP, LDLR, PCSK9, APOE and APOB),

44 The identification of the responsible genes may lead to insights into the pathogen

45 -generation sequencing (NGS) to identify the responsible gene mutation in the family.

46 cardiomyopathy, the likelihood of finding a responsible gene mutation varies.

47 ve a relatively high likelihood of finding a responsible gene mutation when testing is properly appli

48 genetic loci, within which we identified the responsible genes: one locus contains a known xylose-pat

49 rsons with schizophrenia and then mapped the responsible genes onto transcriptome profiles of normal

50 ted with trisomy 21 (Down syndrome), but the responsible gene or genes on chromosome 21 have not been

51 e and concludes with the identification of a responsible gene or genes; the other that begins with a

52 types followed by genotyping to discover the responsible gene or mutation.

53 endent retinal diseases, suggesting that the responsible gene regulates retinal aging, and its impair

54 of heritable factors, but the whereabouts of responsible gene(s) has remained elusive.

55 The responsible gene(s) therefore resides in an interval spa

56 c and physical mapping efforts localized the responsible gene(s) to a well-defined region on human ch

57 To evaluate the mechanisms responsible, gene targeting was used to study long-dista

58 o our family and the new localization of the responsible gene to chromosome 2cen, together with the d

59 We cloned the responsible gene, trafficking protein, kinesin binding 1

60 p to take prior to further searching for the responsible genes via segregation and linkage studies.

61 ocus for SSNS, as a first step to detect the responsible gene, was thus identified.

62 The responsible gene, WASP, has multiple domains, each with

63 To identify the responsible gene, we sequenced the exomes of five indivi

64 To identify the responsible genes, we mapped virulence in F(1) progeny d

65 The identification of the responsible gene will provide new insights into the mole

66 However, identifying the particular responsible genes within these QTL remains a major chall