ライフサイエンスコーパス: restimulate

1 and killed target cells without having to be restimulated.

2 back to the plasma membrane, where it can be restimulated.

3 ey produce significantly more IFN-gamma when restimulated.

4 levels of interferon gamma (IFN-gamma) when restimulated.

5 ation-induced cell death can be triggered by restimulating activated T cells with high concentrations

6 y toward baseline levels by 4 h and could be restimulated after H2O2 but not after UVB exposure.

7 The tumor-reactive cells were then restimulated and cloned by limiting dilution, and the cl

8 Both restimulated and freshly isolated MCMV-immune cells conf

9 ines and/or cytokine antagonists for 5 days, restimulated, and TGF-beta, IL-4, and IFN-gamma producti

10 eared to be up-regulated in both resting and restimulated anergic T cells.

11 This Tr1 phenotype was not restimulated by CD28.

12 D/scid) animals compared with control groups restimulated by Hy(+)MP1(neg) T-APCs.

13 cells expanded by classical DC subsets, were restimulated by IPCs, they proliferated and produced hig

14 er of cell divisions they had undergone, and restimulated by ligation of TCR/CD28.

15 ith the truncated peptides in vivo cannot be restimulated by p46-61 in vitro.

16 te IL-12 was maintained, even when they were restimulated by the activated T-cell signal CD40 ligand

17 e C-terminal determinants can be efficiently restimulated by the naturally generated epitopes from en

18 lymphocytes (CTLs), we studied the effect of restimulating CAR(+) CTLs through their endogenous virus

19 bystander, nonexhausted TILs and in acutely restimulated CD8(+) T cells, we define a pattern of chro

20 Supernatant collected from restimulated cells showed increased amounts of IL-4 (11.

21 unit) was significantly inhibited in fimbria-restimulated cells.

22 tant BALB/cByJ mice also generated secondary restimulated CTL specific for SYNTGRFPPL following in vi

23 ntially growing, growth factor-deprived, and restimulated cultures of malignant versus normal cells.

24 as higher levels of IL-10 in supernatants of restimulated draining lymph node (LN) cells, than did co

25 s from MB49-bearing male mice were unable to restimulate effective HY-specific CTLs or IFN-gamma.

26 n of cytokine gene expression in resting and restimulated effector T helper 1 (Th1) cells.

27 Restimulated effector Th (eTh) cells have reduced levels

28 tiation increases dist.IFN-gamma activity in restimulated eTh1 cells; eTh1 nuclear extracts form incr

29 In contrast, PBMC restimulated ex vivo with live influenza virus preparati

30 the gamma interferon response of splenocytes restimulated ex vivo with M. tuberculosis culture filtra

31 dominant type 1 response in lymph node cells restimulated ex vivo, the expression of type 2 cytokine

32 h a vaccinia virus encoding Ag and IL-2 then restimulated ex vivo.

33 valbumin-complete Freund's adjuvant and then restimulated ex vivo.

34 st Thy1.2+ and transferred Thy1.1+ cells and restimulated ex vivo.

35 teins IE-1, IE-2, and pp65, and subsequently restimulated for 24 hours with the same peptide pools in

36 EHV-1-specific CTL could be restimulated from the spleen up to 26 weeks after the re

37 strains, and by selective abrogation of MPER restimulated, H-2(d)-restricted primed splenocytes by cl

38 hilic lung inflammation and Th2 cytokines in restimulated hilar nodes.

39 The BM-DCs were also capable of restimulating HY-specific CTL and IFN-gamma production.

40 potent antigen-presenting cells ex vivo and restimulate in vivo-primed HDM-specific TH cells.

41 nventionally reared mice, IEL maintained and restimulated in culture had a preferential use of TCR V

42 eta(+/-) TCRalpha(+/-) Foxp3(EGFP) mice were restimulated in culture to yield nTregs (EGFP(+)) and Tc

43 re used in adoptive transfer studies or were restimulated in culture with BiP or type II collagen (CI

44 4 antibodies could convert to Th2 cells when restimulated in IL-4.

45 cells) are capable of producing IL-4 even if restimulated in the absence of IL-4 and in the presence

46 anded in the draining lymph nodes (DLNs) and restimulated in the infected cornea to regulate the dest

47 rmore, we showed that effector T cells, when restimulated in the presence of B7h-deficient APC, exhib

48 the absence of CD8 binding and subsequently restimulated in the presence of CD8 coligation, the prol

49 esence of IL-4, and on established Th2 cells restimulated in the presence of IL-12 and IFN-gamma.

50 2 or DXM for 3 days, washed extensively, and restimulated in the presence of IL-12 still did not prod

51 Even if restimulated in the presence of IL-4, a condition that i

52 preactivated, 4-1BB-expressing T cells were restimulated in the presence of plate-immobilized mAbs d

53 neic FLS in the primary culture, rested, and restimulated in the secondary culture by FLS in the pres

54 When restimulated in vitro by the immunizing cell line, T cel

55 d the gene expression profile of splenocytes restimulated in vitro from Mycobacterium bovis BCG-vacci

56 ar cells from healthy donors were primed and restimulated in vitro with autologous DCs transduced wit

57 pleens were removed and the splenocytes were restimulated in vitro with BALB/c APC, and third party B

58 enhanced capacity to produce IFN-gamma when restimulated in vitro with cytokines or target cells.

59 nterferon-gamma, but not interleukin-4, when restimulated in vitro with dinitrochlorobenzene-derivati

60 ron-gamma secretion of recipient lymphocytes restimulated in vitro with donor antigen was decreased t

61 CTLA-4-/- and wild-type mice were primed and restimulated in vitro with peptide Ag, CTLA-4-/- DO11.10

62 th cross-reactive environmental peptides and restimulated in vitro with PLP139-151 could induce disea

63 ured peripheral blood mononuclear cells were restimulated in vitro with the EBV transformed cell line

64 T cells from Peyer's patches and spleen were restimulated in vitro, and cytokine-specific ELISPOT, EL

65 derived from this protein proliferated when restimulated in vitro.

66 lerant mice have reduced alloreactivity when restimulated in vitro.

67 l and translational activity was observed in restimulated irradiated cells.

68 ytokine production when effector T cells are restimulated is unknown.

69 In vitro restimulated lung cells from sensitized IL-10-/- mice pr

70 Restimulated lymph node cells from L. major-infected BAL

71 ecific IgE and Th2 cytokines produced by OVA-restimulated lymph node cells.

72 rferon and IL-12 secretion, respectively, in restimulated lymph node cells.

73 and Th2 cytokine generation in the lungs and restimulated lymph nodes.

74 and Th2 cytokine generation in the lungs and restimulated lymph nodes.

75 Mice received 4 x 10(7) in vitro-restimulated MCMV-immune cells, 4 x 10(7) freshly isolat

76 d antigen-presenting cells were then used to restimulate memory effector cells against NY-ESO-1 from

77 itro-generated primary effectors and in vivo-restimulated memory effectors by their ability to resist

78 tly, DCs and B cells together contributed to restimulating memory CD4 T cells to secrete IFN-gamma.

79 In the KLH-primed and restimulated mice, the cytokine profile of the autoreact

80 tro, which in turn enhanced their ability to restimulate myelin-specific T cells.

81 on of both proteins was sustained in mitogen-restimulated myocytes, 5-bromodeoxyuridine incorporation

82 f naive CD8 T cells, provided that they were restimulated nearby to produce IL-10.

83 r expanded with interleukin (IL)-2, and then restimulated on day 10.

84 T cells from one patient, restimulated once in vitro, could kill the tumor cell li

85 of Ca2+ oscillations, depolarisation briefly restimulated oscillations.

86 Df-restimulated P2Y(6)-deficient lymph node cells produced

87 ope and constitute the MHC-bound peptide, we restimulated PBMC from a woman with an affected child wi

88 se CTL by a (51)Cr-release assay using 8-day restimulated PBMC from Ty21a vaccinees as effector cells

89 nged in dividing, serum-restricted, or serum restimulated preconfluent cells.

90 not lysed by specific CTL and were unable to restimulate primed Ag-specific T cells.

91 17A production was decreased in the in vitro restimulated skin-draining lymph node cells from the EGF

92 r fluid, and IL-2 and IFN-gamma cytokines in restimulated splenocyte cultures.

93 re liquid chromatography (HPLC) fractions to restimulate splenocytes harvested from mice vaccinated w

94 At various time points after immunization, restimulated splenocytes from 2A-treated mice displayed

95 correlated with peak IFN-gamma production by restimulated splenocytes from infected animals.

96 evelopment of antitumor immune responses, we restimulated splenocytes from MC38-immune mice in vitro.

97 cant reduction in interleukin-17 by in vitro-restimulated splenocytes of TNFR1-deficient mice.

98 and a predominance of IL-17 production from restimulated splenocytes that is dependent upon IL-1R si

99 stemic (antibody levels, cytokine release by restimulated splenocytes) and local (infiltration of imm

100 ic memory CTL or IFN-gamma production by RSV-restimulated splenocytes.

101 ds incorporating these antigens were able to restimulate T cells from more than 91% tuberculosis pati

102 the amount of ESAT-6 and CFP-10 required to restimulate T cells, and in low responders, the overall

103 Adoptive transfer of antigen-restimulated T cells from wild-type to CD11c(-/-) mice p

104 Adoptive transfer of Ag-restimulated T cells from wild-type to ICAM-1(null) mice

105 Adoptive transfer of Ag-restimulated T cells from wild-type to Mac-1-deficient m

106 -1(null) mice or transfer of ICAM-1(null) Ag-restimulated T cells to control mice failed to induce EA

107 EAE, whereas transfer of Mac-1-deficient Ag-restimulated T cells to control mice failed to induce EA

108 EAE, whereas transfer of CD11c(-/-) antigen-restimulated T cells to control mice induced a very mild

109 ylation and kinase activity were enhanced in restimulated T cells, amplifying proximal TCR signaling.

110 Interestingly, bioassays of culture SN from restimulated TH1 but not TH2 cells revealed IL-2 product

111 pathway by which autoimmune and chronically restimulated Th1 cells are eliminated.

112 nd that when LCMV-infected MC57 were used to restimulate the spleen cells, the resulting CTL line los

113 when LCMV-infected JawsII cells were used to restimulate the splenocytes, the resulting line continue

114 ed in the context of LFA-1 costimulation are restimulated, they secrete IL-2 and IFN-gamma, but littl

115 ity with the ability to coexpress IL-10 when restimulated through CD55 or CD28.

116 lines and drops further when CD4 T cells are restimulated through the TCR in vitro.

117 ssed the activation marker CD69 and could be restimulated to produce gamma interferon (IFN-gamma).

118 ing systemic triggering, DC can no longer be restimulated to produce IL-12 in vivo while continuing t

119 These cultures are restimulated twice with peptide-pulsed lymphoblastoid ce

120 4 (T(H1) cells) fail to produce IL-4 even if restimulated under conditions that would cause a naive T

121 retained when the T cells were subsequently restimulated under nonbiasing conditions.

122 e of reexpressing alternative cytokines when restimulated under opposing conditions.

123 e donors make little interleukin (IL)-4 when restimulated under Th2 conditions.

124 ml) plus IL-4 (1000 units/ml) for 1 week and restimulated weekly with FP plus IL-2 (20 IU/ml) induced

125 iNKT cells previously exposed to DB06-1 are restimulated weeks later, they have greatly increased IL

126 he most reliable method to determine when to restimulate with additional immobilized mAb.

127 L secreted interferon-gamma (IFN-gamma) when restimulated with a BCR-ABL peptide, GFKQSSKAL, indicati

128 kine secretion in vivo and by CD4(+) T cells restimulated with Ag in vitro.

129 8, but poor IL-4 responses if they are later restimulated with anti-CD3.

130 the gene encoding interleukin-2 (IL-2) when restimulated with antigen.

131 rats of splenic cells of naive CV-F344 rats (restimulated with BCTD in vitro) before induction of AA

132 Autologous lymphocytes were restimulated with CD80+ tumor cells in the presence of r

133 isolated from the genital tract tissues were restimulated with chlamydial antigen in vitro, and the a

134 In lymphocytes restimulated with CXCL9 and allergen in vitro, CXCL9 dow

135 ti-IL-4 mAb, produced IFNg but not IL-4 when restimulated with donor alloantigen.

136 nce of IL-4, produced IL-4 but not IFNg when restimulated with donor alloantigen.

137 , CTL limiting dilution assays cultures were restimulated with donor cells and IL-2 to reverse anergy

138 btained shortly after the acute episode were restimulated with heparin:PF4 complexes, PF4 alone, hepa

139 ocytes isolated from LCCWE-treated mice were restimulated with LCCWE, we observed significant IFN-gam

140 esponsive genes when primed macrophages were restimulated with low doses of IFN-gamma.

141 , the CD43(-/-) mice produced more IL-5 when restimulated with MOG(35-55) in vitro and demonstrated d

142 ted SEA, produced IL-4, IL-5, and IL-10 when restimulated with native SEA in vitro.

143 omponent of TSL, but they did not do so when restimulated with ovalbumin or unpulsed DCs.

144 not a TH-2-associated cytokine (IL-4), when restimulated with peptide 295-314.

145 eporter cell line pretreated with Ec-LPS and restimulated with Pg-LPS (compared to cells pretreated w

146 red to cells pretreated with medium only and restimulated with Pg-LPS), but not when the reverse trea

147 enocytes from vaccinated and challenged mice restimulated with RSV in vitro.

148 ore, when quiescent serum-starved cells were restimulated with serum, entry into the S-phase was dela

149 Rap1E63-Tg T cells primed in vivo and restimulated with specific Ag in vitro, exhibited reduce

150 4 expression on the cell surface after being restimulated with the GAD peptides in vitro.

151 Compared with S5K-CTL that had been restimulated with the inducer S5K, S5K-CTL stimulated wi

152 imed in vivo with wild-type peptide 322-337, restimulated with wild-type peptide or APLs, and the cyt

153 Furthermore, when T cells were restimulated without IFN-beta, these cells induced less