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2 minutes (interquartile range, 97.7-162.0) in restricted visitation model to 245 minutes (interquartil
5 igh-affinity Gag293-specific TCRs were cross-restricted by up to 5 distinct HLA-DR alleles, accountin
6 ype, epistatic contingencies among mutations restrict evolution to a small number of adaptive paths.
7 ence of centrosomes, but the mechanisms that restrict pole assembly to a bipolar state are unknown.
9 ircuits requires Cre-driver mouse lines that restrict transgene expression to a precisely defined cel
12 ites of neurons, enabling fast and spatially restricted responses to a dynamically changing extracell
13 ding areas decreased dramatically and cranes restricted their activity to a small partially unflooded
14 ncertainty, and those that have done so have restricted their analysis to a portion of the modeling s
15 crocyclic oligomers are rare, mostly because restricting a reaction to a defined number of identical
17 allows users to overcome this limitation by restricting excitation to a narrow illumination plane.
19 ates remained stable in sensitivity analyses restricting the sample to a narrower age range or to pat
24 involves a mechanism of H(+) exchange, which restricts flux to acidic membranes such as synaptic vesi
25 ins are subject to lipid modification, often restricting them to act in a localized manner on respons
26 nal activities of a legal cannabis industry, restricted cannabis availability to adults, and maintain
28 ntrate therapeutics within a unique, cardiac-restricted compartment to allow sustained drug penetrati
29 and gene engineering strategies are used to restrict the MPhi to an appropriate phenotype or to enab
32 n distance and QRS morphological change when restricting pacing points to areas of voltage >0.5 mV.
38 integral components of gene regulation that restrict access to both regulatory sequences and the und
41 hat the ERAP1 SNP rs30187 association is not restricted only to carriers of HLA-B*27 but also found i
42 the index date backwards by 2 years, and we restricted our analyses to cases and controls without a
44 ends of the symmetric proteasome barrel and restricting access to catalytic sites sequestered in the
45 ody expansions via a mechanism requiring MHC-restricted antigen presentation to CD4(+) T cells and st
46 the distribution of signaling proteins that restricts growth to cell ends and targets the cytokineti
48 or concurrently, and assessed the effect of restricting vaccination to certain months of the year.
49 genome divergence were greatly reduced when restricting comparisons to chromatin-accessible sequence
50 able strategy for performing this task is to restrict integration to cues that coincide in space and
54 rmations) have so far remained elusive, thus restricting efforts to develop antiviral treatments and
55 This TBEV-induced NK cell activation was restricted predominantly to differentiated CD57(+)CD56(d
58 ing H1's promotion of chromatin folding that restricts access to DNA methyltransferases responsible f
61 mic imprinting is an epigenetic process that restricts gene expression to either the maternally or pa
62 in TMEM43; and the patient's willingness to restrict exercise and to eliminate participation in comp
63 d-sensing TLRs and indicate checkpoints that restrict their activation to endolysosomal compartments.
66 ls and that senescence is a primary means of restricting tumorigenesis due to epigenetic disruption.
67 ressed in a cell type-specific manner, which restricts its activity to epithelial barriers, particula
68 ds model, in all participants and also after restricting the analysis to euthyroid participants (defi
69 port for parallel execution on clusters, and restricted flexibility to extend the underlying logic pr
70 by triggering nutrient transporter loss and restricting access to extracellular amino acids and gluc
71 seline VA worse than 20/200 were excluded to restrict analyses to eyes at risk of nAMD, the rate of s
72 s regulated salesperson gifts to physicians, restricted salesperson access to facilities, and incorpo
74 ccurs on the millisecond time scale, largely restricting its implementation to fast time-of-flight (T
75 o physiologic and pathologic consequences of restricting thrombin generation to fIIa(MZ), mutations w
76 use expensive optoelectronic components that restrict sensing locations to finger tips or ear lobes d
77 research shows that when children experience restricted access to food, they display increased intake
78 h rainfall (rain-on-snow) can cause 'icing', restricting access to forage, resulting in starvation, l
79 ge volumes at nanoscale resolution have thus restricted vertebrate studies to fragments of circuits.
80 ovel recombinant adeno-associated virus that restricts gene expression to GABAergic interneurons with
81 C serves as a general silencing complex that restricts transcription to gene units in euchromatin.
86 d that the benefits of crowdsourcing are not restricted only to harnessing the time, labor, and funds
87 nse, expression of MHC class II molecules is restricted mainly to hematopoietic cells and thymus epit
91 of salient but irrelevant visual objects and restricts their access to higher stages of visual proces
92 ngue, our results suggest that B44 supertype-restricted immune responses to highly conserved regions
93 nteresting new gene (RING)-type E3s, thereby restricting it to homologous to E6AP C-terminus (HECT) a
94 e or a competing endogenous (ce)RNA for HuR, restricting its availability to HuR target mRNAs and the
96 ity following cochlear implantation has been restricted due to incompatibility between established ne
99 We examine the potential of adult lineage-restricted progenitors to induce fully penetrant GBM usi
100 well-time thresholds used by MHCI- and MHCII-restricted thymocytes to initiate negative selection and
101 and poor water solubility of anti-epileptics restrict absorption, leading to insufficient therapeutic
102 y, we propose a double safety mechanism that restricts PCD to interdigital areas, as the genetic prog
104 expression of Cyp1a1 throughout the body or restricted specifically to intestinal epithelial cells r
106 ycling would deliver a one-two punch to Mtb: restricting access to iron and causing toxic intracellul
107 ction experiments indicate that IRP function restricts bacterial access to iron via the EntC and Feo
108 ays and long-term disease attributions, thus restricting our search to ITPs necessitating health care
110 m a pool of variants that are geographically restricted (i.e., to Kenya or to the region) rather than
113 esponse in most individuals is sufficient to restrict M. tuberculosis to latent infection, but most i
114 cal substrate and size of the RVOT currently restrict PPVI eligibility to less than one-quarter of pa
115 e potential importance of means control (ie, restricting access to lethal means [such as firearms]) a
118 egrated into the walls of the channel, which restricts efficient capture to limited regions of the ch
119 micropatterned substrates are often used to restrict cell migration to linear, quasi-one-dimensional
121 aling that is not modulated by IL-2, thereby restricting responses to low-affinity or low-abundance s
122 ntake and dental caries and on the effect of restricting sugars intake to < 10% and < 5% energy (E) o
123 naling within mucosa-associated microbes and restricted bacterial access to lymphatic tissues of the
124 st practices include legislative measures to restrict access to means of self-harm or suicide and to
125 otein expression in Escherichia coli, we can restrict vibrational delocalization to measure 2D IR spe
126 driven by a nuclear export signal (NES) that restricts GEN1 actions to mitosis when the nuclear membr
127 = 3.7 x 10(-3)), which was stronger when we restricted the investigation to more severe (Stage B) ca
128 es and integrates RNA-seq or PRO-seq data to restrict analyses to motifs recognized by TFs expressed
129 ackwards-in-time coalescent simulation while restricting coalescence to node pairs with overlapping o
130 cular coagulation nor death from shock, thus restricting pathogenesis studies to nonhuman primates.
133 d nuclear localization of VcMid protein that restricted its activity to nuclei of developing male ger
134 ily is localized to the centrosome, where it restricts core duplication to once per cycle and ensures
137 , particularly during early development, has restricted researchers to only scratching the surface of
138 Using an organism's genome as a database restricts metabolite identification to only those compou
139 islation and regulation that inappropriately restrict access to opioid medications for individuals wi
142 cus from pregnant patients was significantly restricted compared to ovulating patients, but not signi
144 for selective absorption of nutrients, while restricting access to pathogens and food-borne antigens.
146 ents had been randomly assigned to treatment-restricted enrolment to patients with tumours wild-type
148 iline available to all patients with MDR TB, restricting bedaquiline usage to patients with MDR plus
150 een direct care and supernumerary nurses and restricting the analysis to patients who had been in the
152 ructure-exhibits theta (4-7 Hz) oscillations restricted primarily to periods of active (REM) sleep.
153 liocene were more likely than geographically restricted species to persist in the temperate zone, sug
156 signal-to-noise ratio, and the use of (11)C restricts its use to PET research centers and hospitals
157 me destabilization at promoters, and H3K4me3 restricts its incorporation to phases of acute transcrip
159 as universal detectors for GC x GC has been restricted mainly due to physical limitations such as in
161 during inflammation, and 12-LO expression is restricted mainly to platelets, these observations demon
162 ion of the priming factor Munc13 exclusively restricted prefusion states to point contacts, all of wh
163 ging, and required either trio sequencing or restricting phasing to population-based haplotypes.
164 e of anthracycline chemotherapeutic drugs is restricted owing to potentially fatal cardiotoxic side e
165 -VLBW subcohort also may reflect biases from restricting the cohort to prematurity, because prematuri
167 inated the normally broad tropism of VSV and restricted infection to primarily the transformed CD4(+)
168 peting endogenous noncoding RNA for miR-150, restricting its capability to promote cell growth and th
169 ecognize prolamine RNA zipcodes required for restricted localization to protein body-ER have previous
170 nsitivity of biophysical techniques normally restrict structural investigations to purified systems,
171 tial isolation of donor and recipient cells, restricting conjugation to rare boundaries between donor
175 overriding limit from the atmosphere, which restricts diazotrophs to regions where dust deposition s
176 nimize T-wave oversensing, and features that restrict therapy to regular rhythms in ventricular tachy
177 te G proteins, indicating that the mutations restricted NTSR1 to relate agonist binding to G-protein
179 To reduce the risk of overestimation bias we restricted analysis to retinoblastoma cohorts with a min
180 cycles in UWDM-2 and UWDM-3 can only undergo restricted motions related to ring flexibility or partia
181 nown, yet the key oscillator responsible for restricting gene expression to S phase has remained elus
183 phatase 6 (ppp6c), a negative regulator that restricts the G1 to S phase progression, is diminished i
185 regions in the group that received previous restricted access to SCM and demonstrated a lack of sens
187 ibiosis to obligatory endosymbiosis and from restricted commensalism to semi-parasitism, with the spe
189 of oncolytic Ad in clinical applications is restricted due to significant liver toxicity and immunog
190 ts to an existing droplet stream has largely restricted droplet chemistry to simple reactions in whic
191 ments, collision-induced dissociation yields restricted information due to simultaneous subunit unfol
193 omain A isoform (FnEDA), which is relatively restricted in distribution to sites of tissue injury.
195 ermaphrodite response to the male pheromone, restricting it to situations in which the presence of a
196 that PU.1 is needed for full proliferation, restricting access to some non-T fates, and controlling
198 frequency with which patients can be tested, restricting testing to specific groups of patients (e.g.
199 ot only drives lung tumor formation but also restricts tumor lineage to squamous cell carcinoma (LSCC
200 use of a stratified block randomisation via restricted web platform to standard of care (control) or
201 utput in WF cells and local inhibition helps restrict responses to stimuli that are both small and mo
203 closely connected to leaf development, which restricts our ability to study the process of chloroplas
205 bleaching in STED/RESOLFT nanoscopy through restricting the scanning to subdiffraction-sized regions
207 urin-activated gene expression suggests that restricting its access to substrates tunes calcineurin s
209 cian education, media strategies, screening, restricting access to suicide means, treatments, and int
210 only on species found in primary forest and restricted in range to Sundaland, and they are independe
211 luding low depths of tissue penetration that restrict PDT to superficial lesions, inability to treat
212 ing that current protocols are effective for restricting CreER activity to supporting cells at mature
213 y viral Vpu and reduces the ability of HLA-C restricted CTLs to suppress viral replication in CD4+ ce
214 tors such as NA might be exported by glucose-restricted mother cells to survive later generations, we
215 urces directly, hampering the ability of the restricted partner to survive and/or reproduce without t
216 can be controlled in prospective studies by restricting analyses to susceptible individuals with an
217 ts, rats were given 5 weeks of continuous or restricted daily access to sweetened condensed milk (SCM
219 a and provide experimental evidence of their restricted ability to synchronize downstream clusters.
220 at Warburg metabolism enables tumor cells to restrict glucose availability to T cells, suppressing an
224 mum and nitrogen dioxide with birth weight, restricting the population to term births to nonsmokers,
226 proteolytic mechanism that is geared toward restricting Bok to that which is bound to IP3Rs, implies
227 than conventional enrichment strategies that restrict enrollment according to the baseline risk of de
230 NCC and FANCE act as substrate receptors and restrict monoubiquitination to the FANCD2:FANCI heterodi
231 i(i) and i(k) alleles of the I locus, which restrict pigment to the hilum or saddle region of the se
232 activities are difficult to establish given restricted access to the region and persistent cloud cov
235 ermline, and, through TAS3-derived ta-siRNA, restricted ARF3 expression to the medio domain of ovule
236 ensembles of model structures that are more restricted compared to the conformational ensemble obtai
237 howed magnetic resonance imaging (MRI) focal restricted diffusion confined to the left temporal and o
238 for developmental toxicity have been largely restricted due to the limited molecular data available f
239 the intra-tumoral nanoparticle transport is restricted due to the presence of hypoxic or necrotic re
240 , a hominoid-specific enzyme with relatively restricted expression to the brain, was critically invol
241 the STCs are proteinase inhibitors, probably restricted in specificity to the pappalysin family of me
242 ght how this work is exposing the previously restricted intracellular space to the potential of thera
244 the model includes diffuse projections from restricted prefrontal areas to the thalamic reticular nu
245 e., transglycosylation and cross-linking) is restricted spatially to the septal cross-wall and tempor
247 ccumbens of the adult mouse, but selectively restricted the upregulation to the indirect striatal out
248 f investigation, but ecologists have largely restricted their attention to the influence of concurren
249 nger alcohol exposure (7 d x 2.5 g/kg, i.p.) restricted these increases to the dorsal striatum, and t
251 duced higher levels of IFN production, which restricted viral spread to the central nervous system.
252 igher levels of interferon production, which restricted viral spread to the central nervous system.
253 le branching, EXO70I is located in spatially restricted zones adjacent to the PAM around the arbuscul
257 pression levels was found to be optimal when restricting analysis to the CD45RA(-)Foxp3(+) fraction.
259 plane using the temporal focusing method and restricting channelrhodopsin to the soma and proximal de
260 obal dataset for model training, rather than restricting data input to the species' native range.
262 rentiation into cardiomyocytes; in contrast, restricting Hdac3 to the nuclear periphery rescues myoge
264 rgetics, sustaining local tumor growth while restricting mitochondrial redistribution to the cortical
266 ion prevent collateral genomic DNA damage by restricting RAG activity to the G1 phase of the cell cyc
268 it's activity from its downstream targets by restricting this activity to the circuit's output-null n
272 rods, suggesting that cis retinol oxidation restricts access to the retina visual cycle to cones.
275 veness creates a positive feedback loop that restricts CynA to the rear and contributes to the establ
277 , poor central nervous system (CNS) exposure restricts its use to the hemolymphatic form (stage 1) of
279 the innate mechanisms by which the placenta restricts microbial access to the intrauterine compartme
282 tioning these drugs, and other insurers have restricted coverage due to their exorbitant costs and th
283 thods are usually in transmission mode, thus restricting the use to thin and transmitting samples.
284 uence homologs between species, even when we restrict our attention to those which are most highly re
286 s, the acceptor sites that it recognizes are restricted predominantly to those having a negatively ch
287 methodology for fitting nonparametric shape-restricted regression splines to time series of Landsat
288 to-inhibitory domain (AID) of Set2 primarily restricts Set2 activity to transcribed chromatin and fin
290 indicated losses of 30% from 1986 to 2014, restricting S. polyschides to upwelling regions at the s
291 r and assimilates in plants remains limited, restricting our ability to use delta(18) O as a tracer o
294 in the wild, efforts are still continuing to restrict the extent to which live virus is distributed i
295 ng this tool, we identified a unique H-2D(b)-restricted epitope to which there was a CD8(+) T cell re
296 , which suggests that strong HC connectivity restricts the degree to which the HC interacts with othe
298 of racial difference in rice consumption, we restricted the analyses to whites only and obtained simi
299 ith an unadjusted analysis and analyses that restricted the cohort to women with depression and that
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