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4 enhancer DNA, and as expected these variants retain the ability to activate open complex formation in
5 1 lost the ability to interact with TSC2 but retained the ability to activate mTORC1, although to a l
6 ced TAK1-independent NFkappaB activation and retained the ability to activate substantial gene expres
8 genes, including p21, Noxa, and Puma, but it retains the ability to activate a small subset of p53 ta
9 n N-terminally deleted mutant of RalGDS that retains the ability to activate Ral proteins but loses t
10 e, encoding the mutant p53R172P protein that retains the ability to activate the cell-cycle inhibitor
12 , subsets of DCs in activated DC populations retain the ability to actively phagocytose particulate A
13 In this study we show that diabetic hearts retain the ability to adapt their metabolism in response
14 oites, which had lost the ability to invade, retain the ability to adhere to erythrocytes, and furthe
15 in contrast to IC and ADC synthase, SgcD has retained the ability to aminate chorismate identically t
16 iminished even though NC mutant Gag proteins retained the ability to assemble spherical particles.
17 ndogenous Lsm4, although this mutant protein retained the ability to assemble with Lsm1-7, associate
19 ant-negative mutant form of myocardin, which retains the ability to associate with SRF but is defecti
20 ive T cells to evade negative selection, yet retain the ability to be activated by self-antigens in t
21 PR/Cas9 and a cytidine deaminase enzyme that retain the ability to be programmed with a guide RNA, do
25 no longer induce significant VLP release but retained the ability to be incorporated as a passenger i
28 ained highly functional within the liver and retained the ability to become highly activated as evide
29 defective in their ability to bind Krh1p but retain the ability to bind another Gpa2p-interacting pro
30 how that JH-linked RGMc mutant proteins that retain the ability to bind BMPs are also able to functio
31 planation of how highly divergent Ly49s that retain the ability to bind cI molecules might have evolv
32 tants, the NiV G glycosylation stalk mutants retain the ability to bind F, indicating that the fusion
34 motility-deficient versions of motors, which retain the ability to bind microtubules and hydrolyze ad
37 though the acyclic cucurbit[n]uril congeners retain the ability to bind to ammonium ions with high af
38 acyclic glycoluril pentamer 5 and hexamer 6 retain the ability to bind to guests typical of CB[6] bu
39 for Plasmodium falciparum virulence and must retain the ability to bind to host receptors while also
40 triguingly, we have found forkhead DBDs that retain the ability to bind very specifically to two comp
41 ted HCR/C that lacked GBP2 binding potential retained the ability to bind and enter Neuro-2A cells.
42 These findings demonstrate that sperm have retained the ability to bind and respond to truncated Cr
45 gated IFIT1/mRNA interaction, whereas IFIT1B retained the ability to bind cap1-mRNA, albeit with redu
46 Cu-NODAGA-PSMA-IgG and (64)Cu-NODAGA-PSMA-Mb retained the ability to bind cell surface PSMA, and both
47 lptA null mutants of strains FA1090 and 273 retained the ability to bind fH when LOS was sialylated.
49 tants that lost the ability to activate Jak2 retained the ability to bind Jak2, thus questioning the
50 s in ATPase activity, though D714E and D714H retained the ability to bind metal ions with high affini
56 howed restricted neutralizing activity, they retained the ability to bind to the E.A244 gp120 HIV-1 e
60 employing other sequences, this DNA aptamer retains the ability to bind aminoglycosides, albeit with
61 ing CUL3 mutant (CUL3 Delta403-459) not only retains the ability to bind and ubiquitylate WNK kinases
63 f TPV-15L revealed no Ig-like domain, but it retains the ability to bind heparin and phosphorylate ne
66 ility to activate speB expression, Rgg(103P) retains the ability to bind to DNA upstream of norA and
67 in PHD2 within the full-length Msc1 protein retains the ability to bind to Swr1 but eliminates the f
68 ts have revealed that although Fli1 DeltaCTA retains the ability to bind to the collagen promoter in
70 discovered the functional core of IncA that retains the ability to both inhibit SNARE-mediated fusio
71 ith synthetic luciferyl adenylate because it retains the ability to carry out the oxidative half-reac
72 ne kinase, Ark, and demonstrated that it has retained the ability to catalyze the phosphorylation of
73 d immunosuppressive functional profile, they retain the ability to change their functional profile to
74 nerated and shown to result in proteins that retained the ability to cleave the first strand of the D
75 to assemble into higher-order complexes but retained the ability to co-immunoprecipitate with ROM-1
79 hydrated ATPS components for multiplex ELISA retain the ability to compartmentalize antibodies and pr
81 eans for exposing rare events in SDEs, while retaining the ability to compute bounds on the probabili
83 endocrine lineage regulator Neurogenin3, and retain the ability to contribute to cells within the pan
84 and CD4(-)CD8(-) T cells were functional and retained the ability to control tumor growth without the
86 ent for forming microcontacts to SAMs) while retaining the ability to deform and flow upon contacting
87 whereas cells with knockdown of HIF1/2alpha retained the ability to degrade plasma membrane Na-K-ATP
89 ferative cells express stem cell markers and retain the ability to differentiate down multiple cell l
90 h cells can self-renew indefinitely but also retain the ability to differentiate into other cell type
91 as differentiated as tissue fibroblasts and retain the ability to differentiate into other cells typ
92 th wild-type controls but the null parasites retain the ability to differentiate to the intracellular
94 ficient thymocytes had a normal lifespan and retained the ability to differentiate, albeit with reduc
95 ed in vitro for at least five passages while retaining the ability to differentiate into multiprocess
98 ing simulated data, we also show that alpine retains the ability to discover true positives, similar
102 the mutants, R142A and D148A, were found to retain the ability to down-regulate reporter RNA transla
103 ic defect in Th2-type lung inflammation, yet retain the ability to elicit pulmonary Th1 antiviral res
105 ng CD34 and a 17-fold increase in cells that retain the ability to engraft immunodeficient mice.
107 T cells, B cells and dendritic cells, while retaining the ability to enhance naive T-cell differenti
108 tive in DNA binding (the S335D mutant) still retains the ability to enhance BRLF1 transcriptional eff
109 established that all mutant proteins tested retained the ability to enter the phloem translocation s
110 o decrease variability between animals while retaining the ability to enumerate transmitted/founder v
112 ghly plastic self-renewing cancer cells that retain the ability to expand ex vivo as tumourspheres, i
113 e with altered molecular characteristics and retain the ability to express c-fos, and Rb is maintaine
114 g following gastrulation, cardiac precursors retain the ability to express markers of the cardiac fie
115 espite these defects, C9orf72 synapses still retain the ability to express presynaptic homeostatic pl
117 s than did infected wild-type mice, and they retained the ability to express tumor necrosis factor al
118 aling attenuation in Tfh cells, because they retained the ability to flux calcium and activate NFAT-t
119 cent transmembrane alpha-helices, M1 and M3, retains the ability to flux cations in this uncoupling P
120 espite the expanded backbone, 1 was found to retain the ability to form a tetrameric quaternary struc
121 rface located on the N-terminal domain still retain the ability to form extended nucleoprotein filame
122 of Rta that are unable to form tetramers but retain the ability to form higher-order multimers are re
124 s and propose that the altered AQP5 proteins retain the ability to form open channels in the cell mem
126 e unable to cleave at recombination hotspots retain the ability to form stable complexes with the hot
127 IL-1R-deficient RAS-expressing keratinocytes retain the ability to form tumors in orthotopic grafts.
128 one lacking all three ectodomain cysteines, retained the ability to form non-covalent dimers, and al
129 nes and arginines are replaced with alanines retains the ability to form amyloid fibrils but is defec
130 elope) is present in the stratum corneum and retains the ability to form covalent inhibitory complexe
131 heir ATPase and transport capabilities still retain the ability to fully use vitamin B12 in vivo.
132 monstrated that, in the absence of AHL, EsaR retains the ability to function as a weak activator of t
133 hylation in recombinant VSV (rVSV) partially retain the ability to G-N-7 methylate a pre-2'-O-methyla
134 oth Mmp14(-/-) and Mmp15(-/-) mammary glands retain the ability to generate intact ductal networks.
136 t advantage of being expandable in vitro and retaining the ability to give rise to multiple neuronal
137 We further demonstrate that S. enterica LT2 retained the ability to grow on 1,2-propanediol as the s
138 neered to express a foreign gene while still retaining the ability to grow to high titers in cell cul
139 ing all three known iron acquisition systems retains the ability to grow in media containing iron che
140 ve individually been changed to alanine, all retain the ability to hydrolyze the cortex to various de
141 supercomplex with MalE cross-linked to MalG retains the ability to hydrolyze ATP and to transport ma
142 Moreover, this discriminatory MLST scheme retains the ability to identify epidemiologically linked
144 of several popular processing methods while retaining the ability to incrementally renormalize data
145 terfere with the IFN signaling because cells retain the ability to induce functional but local antivi
146 These results show that recombinant MVs retain the ability to induce MV-specific humoral immunit
147 ss into the CNS of immunodeficient mice, and retained the ability to induce a strong humoral immune r
149 y loss, the 3-O-desulfonated pentasaccharide retained the ability to induce tryptophan fluorescence c
150 lergenicity and increases safety while still retaining the ability to induce effective desensitizatio
151 with plasmid-cured C. muridarum mutants that retain the ability to infect the murine genital tract, b
152 d that plasmid-deficient Chlamydia muridarum retains the ability to infect the murine genital tract b
153 a+ T cells and whether these converted cells retain the ability to inhibit colitis are not clear.
154 ditis elegans mafr-1 that truncate the C-box retain the ability to inhibit the transcription of RNA p
157 nous target genes and promote apoptosis, but retained the ability to inhibit cell proliferation when
160 ed analogs lose all cytotoxic activity while retaining the ability to inhibit protein translation in
162 ing mutant (V26G/P80R) that interacts with Z retains the ability to inhibit Z function, whereas a Pax
165 mammalian cells confirms that these proteins retain the ability to interact in a heterologous system.
166 ria, and the purified proteins were found to retain the ability to interact in a manner that was depe
167 2 mutants, Munc18-2(R65Q) and Munc18-2(R65W) retain the ability to interact with and stabilize syntax
168 gh mutants do not affect cilia structure and retain the ability to interact with Disheveled, both all
169 main defined by limited proteolysis, did not retain the ability to interact with Rab11, although it w
170 were expressed in mammalian HEK293 cells and retained the ability to interact with a fluorescently la
172 293T cells, although NC mutant Gag proteins retained the ability to interact with cellular membranes
174 ucleotide kinase phosphatase (PNKP) not only retained the ability to interact with partner proteins t
177 that failed to bind to PIH1D1 in vitro fully retained the ability to interact with the R2TP complex a
181 lpha (NT-PGC-1alpha, amino acids 1-270) that retains the ability to interact with and transactivate n
184 the primary E3 ligase of RanBP2, whereas IR2 retains the ability to interact with SUMO1 to promote SU
186 eriments utilizing FEN1 mutant proteins that retained the ability to localize to telomeric repeats re
187 expressed high levels of functional p53 and retained the ability to lyse transformed versus normal c
188 at have differentiated into stalks really do retain the ability to make new tips, we have removed exi
189 n adapting feedforward control of speech but retain the ability to make online feedback corrections;
191 with a dual acylated N-terminal epitope tag retained the ability to mediate HR, consistent with this
192 xhibited impaired anticoagulant activity but retained the ability to mediate PAR-1-dependent signalin
193 ced redistribution towards mitochondria, but retains the ability to mitigate toxicity due to mitochon
194 precursor insect viruses; for instance, HAV retains the ability to move from cell-to-cell by transcy
195 e low baseline levels of Ig in the blood but retain the ability to mutate Ig-associated genes that en
197 69 D5 protein remains stable and soluble and retains the ability to oligomerize and hydrolyze ATP whe
200 terial cells expressing P1-3C transgenes and retained the ability to process P1 polyproteins from mul
201 esults indicate that animals with strabismus retain the ability to produce conjugate adaptation of sm
202 es (CTLs) fail to degranulate, although they retain the ability to produce cytokines, and cytokine le
204 fully downregulate pluripotency markers and retain the ability to produce ES cell colonies; however,
207 efficient slicing activity, these fish have retained the ability to produce miR-451, a microRNA gene
208 ium-responsive subset of CD4(+) T cells that retained the ability to proliferate and express IL-2.
209 restingly, regardless of age, KLRG1(+) cells retained the ability to proliferate and survive in respo
210 of T cells in vivo, but Uqcrfs1(-/-) T cells retained the ability to proliferate in vivo under lympho
213 in tumor-bearing IFN-gamma knockout mice but retained the ability to promote CD8(+)CD44(high) memory
214 also induced comparable immune responses and retained the ability to protect mice against Shigella fl
215 e mesenchymal carcinoma cells within a tumor retained the ability to protect their more epithelial co
216 on transmission in a given environment while retaining the ability to quickly adapt to a new environm
217 intains repetitive character, potentially to retain the ability to rapidly restructure the Ago-bindin
218 icated that transiently primed alphaIIbbeta3 retains the ability to rapidly bind PAC-1 from 2-90 min,
219 onstitutively high sulfate concentration, it retains the ability to re-program its gene expression in
221 icyclic peptides that are cell-permeable and retain the ability to recognize specific intracellular t
222 of highly selective polymeric cavities that retained the ability to recognize PSA post removal of th
223 ils to induce cell surface PS exposure while retaining the ability to recognize carbohydrates and sig
225 of wild-type DLC1 to focal adhesions, but it retained the ability to reduce the intracellular levels
226 unable to catalyze nitrite reduction despite retaining the ability to reduce a proposed intermediate
228 ional stabilization, whereas ICM cells still retain the ability to regenerate TE up to the early blas
230 g the formation of a blastema, however, they retained the ability to regenerate partial hindlimb stru
231 pment of Onthophagus horned beetles and have retained the ability to regulate A/P polarity in traditi
233 ycle arrest, senescence and apoptosis, fully retains the ability to regulate SLC7A11 expression and i
234 eractions indicated that broken helix states retain the ability to relieve membrane-packing stress.
238 omoters (G50DblKo) revealed that this mutant retained the ability to replicate in the simian kidney e
239 to naive-contact ferrets, while concurrently retaining the ability to replicate within ocular tissue
240 rtually all HCC-associated TR mutants tested retained the ability to repress target genes in the abse
241 spatial resolution from ChIP-Seq data, while retaining the ability to resolve closely spaced events t
243 icate that neurons of the degenerating brain retain the ability to respond to growth factors with axo
245 nocytes in patients with active systemic JIA retain the ability to respond to IFNgamma, suggesting th
246 nic Ag stimulation and periodic reactivation retain the ability to respond to local virus challenge.
247 Moreover, cells in the surviving spheres retain the ability to respond to reinduction and thus ma
248 in-knock-out mice and found that these cells retained the ability to respond in a sustained fashion t
250 Most importantly, PKCtheta-deficient T cells retained the ability to respond to virus infection and t
251 1 may be eliminated, but the truncated genes retain the ability to restore editing site conversion in
252 ation forks blocked by protein-DNA complexes retain the ability to resume replication upon removal of
254 e discovered that in-vitro-manipulated HSPCs retain the ability to return to latency after transplant
255 nts of incorporated alpha-galactosylceramide retained the ability to robustly activate NKT cells.
256 at bound C. neoformans but did not ingest it retained the ability to ruffle in response to chemoattra
257 indication on whether or not a species/genus retains the ability to salvage deoxyribonucleosides.
258 ordance with primary WM tumors, MWCL-1 cells retain the ability to secrete high amounts of IgM protei
261 mutations in the dehydrogenase domain still retain the ability to self-associate and bind target pro
266 (RI-10) of LL-37 as the minimal peptide that retains the ability to signal increased expression of GA
268 ron microscopy revealed that nhx1Delta cells retain the ability to sort cargo into intralumenal vesic
269 in contact with antigen-specific CD4 T cells retain the ability to stimulate additional naive T cells
271 than native cashew proteins but importantly retained the ability to stimulate cellular proliferation
272 contrast, an inactive catalytic site mutant retained the ability to stimulate the wild-type KD by di
273 actors with little impact on the vasculature retains the ability to stimulate neural precursors and p
274 rmally function in distinct subcomplexes but retain the ability to substitute for one another so as t
278 Patient-derived mutant PHOX2B constructs retained the ability to suppress cellular proliferation,
279 methyltransferase activity, these mutations retained the ability to suppress the growth defect of th
280 y but did not induce arrest; thus, NKT cells retained the ability to survey antigen presenting cells
281 social insect societies in which individuals retain the ability to switch between reproductive and no
285 e lung, but surprisingly, we find that cells retain the ability to take up siderophores produced by c
287 show that all three PD-linked alphaS mutants retain the ability to transition from the broken helix t
290 plasmacytoid dendritic cells, respectively, retaining the ability to trigger Toll-like receptor 7 ex
292 erficial layers of adult mouse visual cortex retain the ability to undergo reversible experience-depe
293 hydrolytically active and inactive subunits retain the ability to unfold protein substrates and/or c
295 p53(515C/515C) and Emu-myc::p53(515C/+) mice retain the ability to upregulate p21, resulting in cellu
296 taining the V3 sequences of R5-tropic clones retained the ability to use CXCR4, suggesting that seque
298 These findings indicate that EIAV(vMA-1c) retains the ability to use ELR1 for entry and suggest th
299 s in the nsP2 gene, but their capsid protein retains the ability to use the nsP1-specific PS of other
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