ライフサイエンスコーパス: retention time

1 library (containing exact mass fragments and retention times).

2 ion criteria of various matches and relative retention time.

3 ied by mass spectrometry and chromatographic retention time.

4 or very fast separations below 1 min overall retention time.

5 t risk and have a shortened keratoprosthesis retention time.

6 number for a compound class as a function of retention time.

7 cing potency via multivalency or an extended retention time.

8 on, where a feature is defined by a mass and retention time.

9 in class composition to be traced along the retention time.

10 is the rather complicated expressions of the retention time.

11 protein stability and a prolonged chromatin retention time.

12 ide peptide and its composing peptides using retention time.

13 with correct ion ratios and chromatographic retention times.

14 or 97% of the CCS values, compared to 80% of retention times.

15 by accurate mass, MS/MS spectral match, and retention times.

16 ographic variability on the second dimension retention time, a concept based upon hypothetical refere

17 Using UHPLC-UV-MS(E) information (retention time, absorbance at 450 nm, and accurate masse

18 plant tissue extracts and is independent of retention time, abundance, and elemental formula.

19 ates modifications based on a combination of retention time, accurate mass, elemental composition, an

20 identified in 44 samples by comparing their retention times, accurate mass and mass fragmentation pa

21 tentatively identified on the base of their retention times, accurate mass measurements and subseque

22 to data processing, baseline correction and retention time alignment were performed.

23 for pre-processing, analyte quantification, retention time alignment, and analyte grouping across ru

24 tform to detect metabolite peaks and perform retention-time alignment in liquid chromatography/mass s

25 The tool utilizes retention time alignments, accurate mass tolerances, Pea

26 The retention time and accurate mass for each N-glycan were

27 al analytical parameters in combination with retention time and accurate mass information to confirm

28 ic conditions; acquiring simultaneously m/z, retention time and CCS values for each analyte; processi

29 om fractions were collected along the entire retention time and compared with each other to assign th

30 for two-dimensional separation (based on the retention time and drift time information) and identific

31 metry has added a third dimension (alongside retention time and exact mass) to aid in the identificat

32 al clearance but exhibit a much longer tumor retention time and faster normal tissue clearance, indic

33 The GC retention time and GC/MS spectrum of the synthesized 6,6

34 aluation of a new approach to estimating the retention time and hydrodynamic size of nanorods and the

35 s information from the mass-to-charge ratio, retention time and intensity of each peak, together with

36 the glucuronide metabolite was confirmed by retention time and LC-MS/MS fragmentation matching with

37 The transient precorneal retention time and low penetration capacity into intraoc

38 y have different implementations (values) of retention time and mass in different spectra.

39 hich are assigned based on gas-chromatograph retention time and mass spectral signature of the IVOC U

40 Finally, a peak having the same retention time and mass spectrum was also generated pyro

41 pattern, plausibility of the chromatographic retention time and MS/MS spectral interpretation (compar

42 the testing LC-MS data but also improved the retention time and peak area 3% and 6%, respectively.

43 ut, obtaining fast separation (10 min), good retention time and peak area repeatability, (RSD% 0.80 a

44 Excellent calibration linearity, and retention time and peak area reproducibility were obtain

45 a. 2.6 mL per analysis, and CV, below 5% for retention time and peak height, showed the competitivene

46 compound by first comprehensively evaluating retention time and peak shape criteria and then annotati

47 MS(2) fragment intensities as a function of retention time and precursor mass targeted for MS(2) ana

48 The retention time and response characteristics of the syste

49 During in vivo experiments, retention time and separation efficiency were stable and

50 acterized on the basis of its accurate mass, retention time and tandem mass spectral fragmentation pa

51 less than 0.25% and 1.7% on average for the retention time and the signal area, respectively) were o

52 structures in a rapid manner by matching LC retention times and accurate masses.

53 fication as a result of excellent matches in retention times and also allowed quantification.

54 selected to cover a range of chromatographic retention times and biochemical classes.

55 rred-tank reactor with 6.25-10 min hydraulic retention times and constant 900 mA.

56 gas chromatography/mass spectrometry (GC/MS) retention times and fragmentation patterns.

57 DP moieties formed in our study matched the retention times and identification of those observed in

58 total, 251 data for gas-chromatographic (GC) retention times and liquid/liquid partition coefficients

59 xperimentally using gas chromatographic (GC) retention times and liquid/liquid partition coefficients

60 jor metabolites of each drug, which had HPLC retention times and mass fragmentation patterns identica

61 ds in juice were identified by comparing the retention times and mass spectra with those of the stand

62 metric (LC-MS/MS) analysis revealed that the retention times and mass spectral properties of syntheti

63 t the relative standard deviations (RSD%) of retention times and peak areas of spiked samples were le

64 Within day and day-to-day repeatabilities of retention times and peak areas were below 0.5% and 3.5%

65 Peak identification was verified by retention times and spikes with external standards.

66 identified by comparison with pure standard retention times and UV spectra.

67 w operating voltage, high ON/OFF ratio, long retention time, and good stability.

68 p-value), fold change, mass-to-charge ratio, retention time, and intensity.

69 DBle database, which contains accurate mass, retention time, and MS/MS fragmentation data as well as

70 rary of 85 hydroxyl compounds containing MS, retention time, and MS/MS information was constructed fo

71 concentration of parent compounds, hydraulic retention times, and chlorine contact times.

72 tron impact mass spectrometry fragmentation, retention times, and library searching.

73 labeling and changing peptide charge states, retention times, and masses.

74 e a wide range of memory states, long memory retention times, and protection against unavoidable nois

75 ousands of peaks with a unique m/z ratio and retention time are routinely detected from most biologic

76 Both mass spectra and GC retention times are matched to those of standards; howev

77 ween chromatography well-resolved isomers as retention times are not taken into account.

78 rutinoside (SRBAI = 3.01) eluted at the same retention time as the unknown peak.

79 n structures using their accurate masses and retention times based on a glycan library.

80 sing UV-visible spectroscopy and a HPLC peak retention time-based method, the two acid dissociation c

81 branched alkanes and cyclic compounds) in 11 retention-time-based bins.

82 k heights (21% relative standard deviation), retention times (better than 1% relative standard deviat

83 method was identified the one with a shorter retention time, better resolution, and greater peak heig

84 s of biological activity and chromatographic retention time between the synthetic peptides and natura

85 aks/ions that have different chromatographic retention times but are detected within a single SRM tra

86 (domestic versus industrial), and hydraulic retention time can affect the concentrations of psychoac

87 The charge retention time can maintain over 100 000 s.

88 two-dimensional gas chromatography (GC x GC) retention times can be used to predict 26 relevant prope

89 ions are used along with intensity profiles, retention time characteristics, mass defect, and isotope

90 durance, high thermal stability and suitable retention time, compared to electret and organic nano-fl

91 of the FT-ICR MS (<1 Hz), a database driven retention time comparison, as commonly used for low reso

92 For species with longer retention times, complete chromatographic peaks had to b

93 oviding initial preprocessing bulk nonlinear retention time correction at the raw data level.

94 on the measure of their mixture scores after retention time correction using a partial linear regress

95 olomic workflow including feature detection, retention time correction, alignment, annotation, statis

96 ith (-)-alpha-pinene, the highest and lowest retention time-courses were detected at pH 9 and pH 7 as

97 This method exhibits good reproducibility in retention times (CVs < 3.43%) and high mass accuracy (<3

98 ated excellent resistive switching with high retention time, cyclic endurance, and low set/reset volt

99 The computational generation of gradient retention time data for retrospective detection of suspe

100 The gas chromatography retention time data indicates that the cycloalkane ring

101 optimal peak models that are both data- and retention-time-dependent.

102 For comprehensive assessment of retention time differences between light/heavy pairs und

103 arched for pairs of peaks that have mass and retention time differences corresponding with those of s

104 SEC clearly shows different profiles (i.e., retention time differences) for rhASA when the chromatog

105 p models to enable prediction of delayed HIC retention times directly from sequence.

106 median mass accuracies below 12 ppm, median retention time drifts of less than 0.73 s and coefficien

107 ins in >1500 LC-MS runs, the SD range of the retention time during continuous operation was substanti

108 and show the complex relation of dead time, retention time, efficiency, and optimum velocity with th

109 Column length, retention time, elution volume, extracting solution and

110 ntifiers with detection of features based on retention time, FAIMS dispersion field and compensation

111 s data-rich chromatograms in the form of m/z-retention time features.

112 h is associated with a mass-to-charge ratio, retention time, fold change, p-value, and relative inten

113 Another major challenge is that the observed retention time for a single metabolite can also be signi

114 he first dimension (1D) separation, relative retention time for the second dimension separation (2Dre

115 As columns age and differ between systems, retention times for comprehensive two-dimensional gas ch

116 The potential to resolve retention times for individual components within the com

117 ot-mean-square (RMS) residual differences in retention times for matched peaks suggests that global,

118 onship (QSRR) model was developed to predict retention times for new analytes, based only on their ch

119 e new algorithm achieves the best matches of retention times for test analytes, avoids some artifacts

120 The retention times for the analytes were reproducible withi

121 The data set comprised retention times for two series of organic modifier conte

122 y COSMO-RS against experimentally determined retention times from gas chromatography-mass spectrometr

123 (11)C-GMO also had a long neuronal retention time (>200 h).

124 l size, SN-NPM possessed superior long tumor retention time (>5days) and much higher accumulation in

125 inuous bioreactors operated at low hydraulic retention times have rarely been explored for reductive

126 At a combined hydraulic retention time (HRT) for both processes of 9 h, the effl

127 gular adjustment of pond depth and hydraulic retention time (HRT) in response to seasonal changes.

128 When steady state with a hydraulic retention time (HRT) of 1 day was reached, the process a

129 chemical oxygen demand (COD) at a hydraulic retention time (HRT) of 11 h and reduced about 50% suspe

130 mperature (>55 degrees C) at short hydraulic retention times (HRT).

131 ere able to recover within 24 h (3 hydraulic retention times (HRTs)) and resume removal near 95%.

132 fluences of slag composition, void hydraulic retention time (HRTv), temperature, and wastewater quali

133 eural networks to the prediction of gradient retention time in archived high-resolution urine analysi

134 e highest yet observed tumor cell uptake and retention time in prostate cancer cells.

135 successfully confirmed with respect to their retention time in the analytical system.

136 We operated the MPPC with a 9 day hydraulic retention time in the anode.

137 ne coronary model but differ considerably in retention time in the vessel wall.

138 As a consequence retention times in 2 dimensions and mass spectra at vari

139 regression model, on the basis of normalized retention times in 2D separation space ((1)t(R) and (2)t

140 ily distributed in the body and have shorter retention times in highly permeable organs than higher-d

141 ction of a database with accurate masses and retention times in order to unravel the mass spectral co

142 r efforts to unify the expression of peptide retention times in proteomic liquid chromatography-mass

143 ial least-squares method for predicting UPLC retention times in reversed phase mode.

144 diction of antibodies likely to have delayed retention times in the assay.

145 Wraparound peaks are compounds with retention times in the second dimension that are longer

146 Earlier studies have shown that retention times in this assay can be correlated to amino

147 When retention times increase sharply between 10/90 and 5/95

148 e interest of Scout-MRM method regarding the retention time independency, multiplexing capability, re

149 educed molecular mass and estimated compound retention time information that can be extracted by our

150 polar analytes based on GC x GC chromatogram retention time information.

151 ting all the relevant analytical parameters (retention time, ion path settings, and response factor)

152 computing predictions for isobaric compound retention time is also discussed.

153 The intertrapping column retention time is shown to be sufficiently reproducible

154 use database containing accurate m/z values, retention times, isotopic patterns, full MS, and MS/MS s

155 The study resulted in an accurate mass retention time library for targeted profiling of skin ce

156 enerate a theoretical in-source spectrum and retention time library.

157 erun in electron ionization (EI) mode with a retention time locked method using a GC-QTOF-MS pesticid

158 l identification by matching chromatographic retention times, mass spectra, and also product ion spec

159 nd identified with UHPLC-MS by comparison of retention times, mass spectra, in-source CID spectra, an

160 Spectra and LC retention times matched those of authentic standards.

161 etabolites positively identified by mass and retention time matches to the dansyl standard library an

162 elenocyanate (SeCN(-)) in such waters, using retention time matching and confirmation by electrospray

163 The retention time measured at 85 degrees C is over 3 x 10(4

164 tandem column separations based on a single retention time measurement on each column.

165 introduced, providing a more stable relative retention time measurement.

166 operated under high inlet pressure using the retention time method.

167 ation of single transition per compound with retention time misidentifies 30% of the targeted data an

168 vant chromatographic and spectroscopic data (retention time, molecular ions with the respective ion a

169 such as false discovery rate (FDR) control, retention time normalization and handling of post-transl

170 ibit incidental differences in intensity and retention time, not related to actual chemical differenc

171 ycloSal triesters was performed based on the retention times obtained by reversed phase HPLC.

172 e consumption of CO was achieved with CO gas retention time of 0.2 d.

173 at their last follow-up, corresponding to a retention time of 396 patient-years or 1.42 years/kerato

174 chromatographic conditions were sought: (1) retention time of a single analyte within the range of 4

175 sted the ability of the model to predict the retention time of all the compounds.

176 measuring, through a mass spectrometer, the retention time of deuterium oxide injected in the column

177 p1 at Ser-637 on mitochondria, enhancing the retention time of Drp1 puncta on mitochondria during the

178 nomeric or fibrillar alphaSyn, decreased the retention time of exogenously added Ca(2+), promoted Ca(

179 h the development of new expressions for the retention time of ionizable analytes.

180 Expressions for the retention time of ionogenic analytes eluted under multil

181 ity with chemical similarity or proximity in retention time of ISs to the analyte.

182 concentration, can differentially affect the retention time of MinD and MinE, leading to spatiotempor

183 i-states were clearly distinguishable with a retention time of over 10 years at room temperature.

184 The QSRR-DoE computed retention time of pharmaceutical test analytes and subse

185 k pair rebaudioside A and stevioside and the retention time of rebaudioside D.

186 On the other hand, FKBP52 favors the nuclear retention time of RelA, its association to a DNA consens

187 complex transition lists, regardless of the retention time of targeted surrogate peptides.

188 shown to be highly reproducible in terms of retention time of the analytes (intraday; 0.002-0.034% R

189 ted to be advection due to the low hydraulic retention time of the lake, followed by volatilization.

190 tion of P and inorganic C, and low hydraulic retention time of voids reduced the filter longevity.

191 E) model was developed, able to describe the retention times of a mixture of pharmaceutical compounds

192 nment algorithm is also developed, where the retention times of all peaks are first transferred into

193 atograms, it often is desirable to align the retention times of chromatographic features, such as ana

194 bond linkage was established by matching the retention times of cysteine-containing peptides and conf

195 In addition, the relative retention times of multiple species within a compound cl

196 raphic alignment requires a mapping from the retention times of one chromatogram to the retention tim

197 aggregation is a reason behind reported long retention times of polymer microparticles in organisms.

198 ved a linear correlation between FcRn column retention times of the antibody variants and the termina

199 e retention times of one chromatogram to the retention times of the other chromatogram.

200 e exact masses of the molecular ions and the retention times of TPs were identified.

201 e Euclidean distance of the first and second retention times of two blobs and the Pearson's correlati

202 t chromatographic model able to describe the retention times of weak acids and bases in all possible

203 A separation repeatability (RSD in retention time) of 1.4% (n = 5) was obtained for liposom

204 ve two-dimensional (2D) separation (drift vs retention times) of naphthenic acids (NAs).

205 correlated with peptide molecular weight and retention time on a reversed phase LC column.

206 inorganic C concentration and void hydraulic retention time on filter longevity and P retention capac

207 rt ICPMS signal spikes into NPs injected, NP retention time on the HDC column to NP size, and ions de

208 Their robust identification is based on retention times, on the generation of fragmentation tree

209 By use of LC retention time, one sMRM survey scan transition, and a l

210 by day-to-day nonlinear signal drifts in LC retention time or batch effects that complicate comparis

211 ch can resolve even components with the same retention time or with similar mass fragmentation spectr

212 s also resulted in doubling of the hydraulic retention time over the temperature ramp.

213 mbine all pieces of evidence (e.g., expected retention times, peak shapes, isotope distributions, fra

214 d/base behavior, octanol/water partitioning, retention time prediction and finally toxic effects (mut

215 k protein database and de novo searches, the retention time prediction model permitted reduction and

216 A retention time prediction model was established using th

217 ical similarity scoring, random forest based retention time prediction, text-mining based false posit

218 tributions from isomers, and to characterize retention time profiles for homologous series is shown,

219 While pure advective flow with shorter retention times promotes rapid initial carbonation, pure

220 ct ions was possible due to the reproducible retention times provided by the nano-HPLC chip.

221 roughout each experiment demonstrates a mean retention time relative standard deviation (RSD) of <0.3

222 successive decreases in the parameter solids retention time) relative to stable operational condition

223 expansions of HSQC-spectra, HPLC parameters (retention time, relative retention factor), UV/Vis and m

224 ions by nUHPLC-nESI-TOFMS revealed excellent retention time repeatability with <1% coefficient of var

225 Retention times reproduced well with RSD values of 2.6%

226 erfluoroalkyl acid (PFAA) fragmentation, and retention time reproducibility among replicate extractio

227 The retention time reproducibility was very good in run-to-r

228 Good retention-time reproducibility (RSD < 0.17%) demonstrate

229 sed in the analysis, and (iii) the estimated retention-time reproducibility of the chromatographic me

230 HPLC profiles were compared for retention time, resolution, and peak heights.

231 to peak area, peak width at half height, and retention time (respective relative standard deviations

232 ved chromatogram with excellent precision in retention time revealed seven vitamin E components in th

233 mprised of the detected ions, their relative retention times (RRTs) and intensities (from LC-MS analy

234 ability in terms of peak area (RSD<2.9%) and retention time (RSD<0.2%) both for standards and real sa

235 fractions (A and B) of RP-HPLC collected at retention time (RT) 24 and 28min respectively correspond

236 Retention time (RT) alignment, which is required to ensu

237 etreatment including baseline correction and retention time (RT) alignment.

238 arbonyl metabolites with each containing MS, retention time (RT), and MS/MS information.

239 de peaks are linked based on similarities in retention time (rt), mass or peak shape after rt alignme

240 ers: molecular ion mass, MS/MS spectrum, and retention time (RT).

241 Peak retention times (RT) from the LC-MS and LC-EC system wer

242 systems with relative standard deviations of retention times (RT; n = 6) typically between 2 and 5%.

243 little attention has been afforded to using retention times (RTs) to distinguish compounds and for l

244 (150 injections), with minimal variations of retention time (SD < +/- 0.03 min).

245 The method provides reproducible retention times (SD < 0.05 min), limits of detection (LO

246 ized, aiming at an overall separation with 2 retention time segments, while reversed-phase separation

247 uring the separation, it does not affect the retention times, separation efficiencies, or resolutions

248 l user interface, multithreading capability, retention time shift model and reproducibility.

249 ty), due to several analytical errors (e.g., retention time shift, lack of repeatability in m/z scans

250 ysis and adopted on-the-fly recalibration of retention time shift, which provided better throughput o

251 Restrictions in separation and retention time shifting, known from isothermal and norma

252 e original retention and our observations of retention time shifts of gemcitabine/metabolites on PGC

253 temperature programs, thus involving larger retention time shifts than the first sample set.

254 mation (artifacts), including background and retention time shifts.

255 osition affect reverse phase chromatographic retention times: sialic acid addition increases glycopep

256 sialic acid addition increases glycopeptide retention times significantly; replacing the N-acetylneu

257 suspended solid (MLSS) concentrations, solid retention time (SRT) and dissolved oxygen (DO) concentra

258 o allow for growth (40-50 days) and a solids retention time (SRT) that allows establishment of L-GLDA

259 ugated metabolites and analogues, (ii) solid retention time (SRT), (iii) fractions sorbed onto solids

260 ere operated at 15 degrees C at short solids retention times (SRT; 0.24-2.8 days), hydraulic contact

261 that, for reactors with 10 and 40 day solids retention times (SRTs), complete nitrification was accom

262 ated with 8 cycles per day and at two solids retention times (SRTs).

263 ing batch membrane bioreactor) at two solids retention times (SRTs): 20 and 5 days.

264 The method extracts retention times (t(R)), spectra, and signal intensity fr

265 plex mixture" by separating components by GC retention time, t(R), and mass-to-charge ratio, m/z, whi

266 tent with N-oxides since the TP had a higher retention time than the precursor, a characteristic of t

267 that MIG1 was enriched in species with lower retention times than those derived from the parent strai

268 dentified by comparison of mass spectrum and retention time to those of pure standards.

269 ries, thus enabling automatic calculation of retention time tolerance windows.

270 inating couples [mass-to-charge ratio (m/z); retention time (tR)] and on the most intense peaks.

271 Chromatographic peak maxima (serving as the retention time, tR) above a user specified signal thresh

272 erent Soret coefficients, and thus different retention times, under identical experimental conditions

273 meters for feature selection, namely m/z and retention time values.

274 and structures and their accurately measured retention time values.

275 t certain parameters (e.g., second-dimension retention time variability, first-dimension band broaden

276 ) chromatograms typically exhibit run-to-run retention time variability.

277 Most analyte retention times varied </=0.2 min over the relatively sh

278 actory results especially in cases where the retention time varies linearly with the programmed gradi

279 ptive immune responses against Ad, and blood retention time was markedly prolonged by PEGylation.

280 No variability in retention time was observed.

281 The retention time was of 90s and the elution was carried ou

282 Solids retention time was set to 9-16 days.

283 is of the deduced neutral molecular mass and retention time, we have also developed a new alignment a

284 ctivity of a tandem column separation is the retention time weighted average of selectivity from each

285 Both mass tolerance and difference in retention time were further used to increase the confide

286 aldehyde content and decrease of neutral red retention time were observed at 100 and 1000 mug kg(-1)

287 e overall errors in the fitted and predicted retention times were 1.9% and 1.7%, respectively, wherea

288 n a higher organic mobile phase composition (retention times were approximately 30% later in methanol

289 Deviation in retention times were observed and attributed to small ex

290 Replicate modulated peak areas and retention times were reproducible to <5%.

291 Predicted retention times were within 0.5 min of experimental valu

292 es generated by APLI were detected along the retention time which enabled a differentiation between b

293 N-glycolyl variant leads to slightly reduced retention times, while O-acetylated sialic acid-containi

294 election of the optimal set of fragments and retention time windows for target analytes in GC-SIM-MS

295 r chromatographic features such as peaks and retention-time windows.

296 This illustrated the change of analyte retention time with experimental conditions depending on

297 literature model was used to relate analyte retention time with mobile-phase pH and organic modifier

298 ching acquired pollen-lipid mass spectra and retention times with the NIST/EPA/NIH mass-spectral libr

299 grams exhibited excellent reproducibility in retention time, with relative standard deviations of 0.0

300 (2) baseline separation of two analytes with retention times within the range of 4-10 min.