ライフサイエンスコーパス: retinal disorder

1 ye, develops depigmented patches, indicating retinal disorder.

2 a non-progressive, clinically heterogeneous retinal disorder.

3 represent an as-yet unidentified locus for a retinal disorder.

4 ficiency of CRX is not sufficient to cause a retinal disorder.

5 transfer as a strategy for the treatment of retinal disorders.

6 Netherlands, a tertiary referral center for retinal disorders.

7 l diagnosis includes various optic nerve and retinal disorders.

8 underlying common pathology in degenerative retinal disorders.

9 17.45), respectively among cases with vitreo-retinal disorders.

10 ontribute to RPE cell death in both of these retinal disorders.

11 novel therapeutic strategy for treatment of retinal disorders.

12 r time-domain OCT (TD-OCT) in the imaging of retinal disorders.

13 ith age and is particularly abundant in some retinal disorders.

14 targeting 105 genes implicated in inherited retinal disorders.

15 ment epithelial cells with aging and in some retinal disorders.

16 ome characteristics similar to human flecked retinal disorders.

17 tinal tubulation (ORT) formation in advanced retinal disorders.

18 at promise for the treatment of degenerative retinal disorders.

19 .5%), retinal detachment (11% vs. 0.8%), and retinal disorder (28% vs. 2%) compared with controls.

20 lied to any of the existing mouse models for retinal disorders and may be valuable for documenting im

21 rauma, infection and nutritional deficiency, retinal disorders, and other congenital abnormalities we

22 ath is the root cause of vision loss in many retinal disorders, and there is an unmet need for neurop

23 le explanation would be that these different retinal disorders are caused by mutations in different g

24 herapeutic implications for the treatment of retinal disorders are discussed.

25 Glaucoma and other retinal disorders are some of the major complications in

26 ession perturbations in pathogenesis of such retinal disorders as proliferative vitreoretinopathy and

27 We describe a distinct retinal disorder, autosomal-recessive bestrophinopathy (

28 inisce about caring for patients with common retinal disorders before there was access to the diagnos

29 es a unique opportunity to gain insight into retinal disorders by enabling phenotypic correlation wit

30 tinal pigment epithelium, as seen in various retinal disorders, causes photoreceptor loss and subsequ

31 avimaculatus; FFM) is an autosomal recessive retinal disorder characterized by a juvenile-onset macul

32 nitis pigmentosa, is a progressive inherited retinal disorder characterized by photoreceptor cell dea

33 erred to as "rod monochromacy"), is a severe retinal disorder characterized clinically by an inabilit

34 cally and genetically heterogeneous group of retinal disorders characterized by nonprogressive impair

35 e NYX, which encodes nyctalopin, lead to the retinal disorder congenital stationary night blindness w

36 s diabetes mellitus and hypertension, vitreo-retinal disorders could be of future public health impor

37 ated macular degeneration and most inherited retinal disorders culminate in the same final common pat

38 to develop novel prophylactic approaches for retinal disorders elicited by LBs.

39 Patients with ONH and congenital retinal disorders exhibited more severe visual acuity de

40 The congenital retinal disorder group had no significant change in visu

41 One fourth of the subjects with vitreo-retinal disorder had low vision.

42 ment epithelial cells with aging and in some retinal disorders have been implicated in the etiology o

43 t spot where several phenotypically distinct retinal disorders have been mapped in the past year.

44 For many retinal disorders, however, targeting of therapeutic vec

45 uating the gene defects underlying inherited retinal disorders in dogs.

46 e a safe and effective strategy for treating retinal disorders in humans.

47 The prevalence of vitreo-retinal disorders in this Nepalese population was 5.35%,

48 of pathologic processes in a wide variety of retinal disorders including monogenic retinal dystrophie

49 ment of therapeutic strategies for inherited retinal disorders is a growing area of research.

50 rying these mutant alleles when studying new retinal disorders is recommended.

51 an excellent candidate for several X-linked retinal disorders mapping within this interval.

52 erve hypoplasia (ONH; n = 23), or congenital retinal disorder (n = 36).

53 ify additional candidate genes for inherited retinal disorders, novel retina/pineal-expressed EST clu

54 II/II children had an increased incidence of retinal disorders (odds ratio, 2.43 [95% CI, 1.66-3.56])

55 ssociated with a higher prevalence of vitreo-retinal disorders (P < 0.001).

56 Achromatopsia 2, an inherited retinal disorder resulting in attenuation or loss of con

57 What is the impact of the inherited retinal disorder, retinal degenerate (rd/rd), on the str

58 phenotypic similarities to the human flecked retinal disorder retinitis punctata albescens.

59 in a number of degenerative and inflammatory retinal disorders such as age-related macular degenerati

60 during aging, trauma, or during a variety of retinal disorders such as age-related macular degenerati

61 epithelium (RPE) is a hallmark of aging and retinal disorders such as Stargardt disease and age-rela

62 Only one inherited retinal disorder, the enhanced S cone syndrome (ESCS), s

63 gy, and of managing various other peripheral retinal disorders to prevent retinal detachment (RD).

64 ry via the sclera is a promising approach to retinal disorder treatments that require access to the p

65 ce of low vision and blindness due to vitreo-retinal disorders was 1.53% (95% CI, 1.18 - 1.97) and 0.

66 The overall prevalence of vitreo-retinal disorders was 5.35% (95% CI, 4.67 - 6.09).

67 The population prevalence of other retinal disorders were hypertensive retinopathy 0.88%, m

68 The flash ERG is most useful in diffuse retinal disorders, whereas the multifocal ERG is superio

69 egeneration (AMD) was the most common vitreo-retinal disorder with a prevalence of 1.50% (95% CI, 1.1

70 This unique retinal disorder with dual anomaly in visual processing

71 rogeneous group of non-progressive inherited retinal disorders with characteristic electroretinogram

72 ystrophy (IRD) is a broad group of inherited retinal disorders with heterogeneous genotypes and pheno

73 sults are relevant to clinically significant retinal disorders with vascular pathologies, including d