ライフサイエンスコーパス: retinal pigment

1 teral risk factors for CNV (large drusen and retinal pigment abnormalities) incurs $907 (95% CI, -$63

2 Submacular CC dropout without retinal pigment eipthelial (RPE) loss was observed in al

3 We recently developed a retinal pigment ephithelium (RPE)-choroid preparation to

4 jor AMD-related clinical signs (soft drusen, retinal pigment epitelium, defects/pigment mottling, dep

5 tal implantation of human levodopa-producing retinal pigment epithelial (hRPE) cells in parkinsonian

6 Retinal pigment epithelial (RPE) cell death is a hallmar

7 atrophy (GA), is characterized by extensive retinal pigment epithelial (RPE) cell death, and a cure

8 of complement-containing deposits under the retinal pigment epithelial (RPE) cell layer is a pathogn

9 ding of the immune response, we infected the retinal pigment epithelial (RPE) cell line, ARPE-19, wit

10 the visual cycle adducts that accumulate in retinal pigment epithelial (RPE) cells and are a hallmar

11 ounts of MMP-2 and MMP-9 released by primary retinal pigment epithelial (RPE) cells and iris pigment

12 on, is characterized by irreversible loss of retinal pigment epithelial (RPE) cells and photoreceptor

13 immunogenic, while autologous hiPSC-derived retinal pigment epithelial (RPE) cells are immune tolera

14 isretinoid constituents of the lipofuscin of retinal pigment epithelial (RPE) cells are known to phot

15 lly in photoreceptor cells and accumulate in retinal pigment epithelial (RPE) cells as lipofuscin; th

16 pithelial to mesenchymal transition (EMT) of retinal pigment epithelial (RPE) cells is a critical ste

17 spent photoreceptor outer segments (POS) by retinal pigment epithelial (RPE) cells requires several

18 s of lipid mediators biosynthesized in human retinal pigment epithelial (RPE) cells that are oxygenat

19 is capable of transdifferentiating cultured retinal pigment epithelial (RPE) cells towards a neurona

20 ession specifically in Muller cells, but not retinal pigment epithelial (RPE) cells, rescued the reti

21 (1% O2) to a low glucose condition by using retinal pigment epithelial (RPE) cells, which are a cruc

22 nkers to release conjugated cargo within the retinal pigment epithelial (RPE) cells.

23 n ion channel in the basolateral membrane of retinal pigment epithelial (RPE) cells.

24 opsin is present in the apical microvilli of retinal pigment epithelial (RPE) cells.

25 is associated with dysfunction and death of retinal pigment epithelial (RPE) cells.

26 ng frequency were as follows: Bruch membrane/retinal pigment epithelial (RPE) complex, 78.22 (24.39);

27 at the ARMS2/HTRA1 locus with subretinal/sub-retinal pigment epithelial (RPE) hemorrhage related to n

28 Knockdown of CEP104 in retinal pigment epithelial (RPE1) cells resulted in seve

29 ures included overlying drusen (n = 9; 53%), retinal pigment epithelial alterations (n = 9; 53%), sub

30 ed controls, TNF-alpha mRNA was increased in retinal pigment epithelial and choroidal tissue, and TNF

31 Fundus examination revealed midperipheral retinal pigment epithelial atrophy and intraretinal pigm

32 Conclusions and Relevance: Retinal pigment epithelial atrophy preceded CC loss in g

33 variate analysis, visual acuity at referral, retinal pigment epithelial atrophy, and macular scarring

34 amino acid phenylalanine (Phe) between human retinal pigment epithelial cell line (ARPE-19) and tachy

35 proximal tubular cell line (TEC) and a human retinal pigment epithelial cell line (ARPE-19).

36 Knockdown of Tgifs in a human retinal pigment epithelial cell line also increased EVI5

37 Retinal pigment epithelial cells (ARPE-19 and B6-RPE07)

38 (alphaB) is exported out of the adult human retinal pigment epithelial cells (ARPE19) packaged in ex

39 (iPSC), and differentiated these cells into retinal pigment epithelial cells (RPE) to study the mech

40 ) and pigment changes indicative of reactive retinal pigment epithelial cells and photoreceptor degen

41 ic towards human primary blood leukocytes or retinal pigment epithelial cells at effective concentrat

42 Human retinal pigment epithelial cells were treated with vario

43 inner segments and to the apical surface of retinal pigment epithelial cells where it might be invol

44 c glycolysis, increased after stimulation of retinal pigment epithelial cells with LPS or poly(I:C),

45 lso tested against the noncancerous ARPE-19 (retinal pigment epithelial cells) cell line, in order to

46 to individual cells, such as photoreceptors, retinal pigment epithelial cells, and blood cells in the

47 rion assembly compartments in differentiated retinal pigment epithelial cells, infected AmEpCs made d

48 N) was detected in the conditioned medium of retinal pigment epithelial cells, interphotoreceptor mat

49 the copolymers were shown to be non-toxic to retinal pigment epithelial cells, studies of drug releas

50 ORF45 tegument protein were tested in human retinal pigment epithelial cells.

51 m (pCRP) upregulates IL-8 and CCL2 levels in retinal pigment epithelial cells.

52 sence of hard, crystalline, and soft drusen; retinal pigment epithelial changes; choroidal neovascula

53 be operative that protect the foveal retina-retinal pigment epithelial complex.

54 e, type and area, increased retinal pigment, retinal pigment epithelial depigmentation, neovascular l

55 The retinal pigment epithelial detachment improved in 13/15

56 oidal neovascularization location as well as retinal pigment epithelial detachment internal reflectiv

57 of subretinal hemorrhage, serous detachment, retinal pigment epithelial detachment, and regression of

58 vacizumab can show marked improvement in the retinal pigment epithelial detachments and persistent po

59 receptor loss precedes clinically detectable retinal pigment epithelial disease in STGD1.

60 etinal fluid compared to intraretinal or sub-retinal pigment epithelial fluid.

61 h the primary clinical features of STGD1 are retinal pigment epithelial lesions, adaptive optics scan

62 ernatively, limitations to detection of true retinal pigment epithelial lipofuscin content.

63 relating to pathways controlling retinal and retinal pigment epithelial maintenance.

64 vascular endothelial growth factor activity, retinal pigment epithelial responses to aging, and oxida

65 ts flow was limited to the subretinal or sub-retinal pigment epithelial space.

66 Retinal pigment epithelial tears were seen in 95% of eye

67 r uptake and delivery of MPO to lysosomes of retinal pigmented epithelial (RPE) cells acts to clear t

68 d modify proangiogenic signaling produced by retinal pigmented epithelial (RPE) cells under different

69 dified and modified mRNA can be delivered to retinal pigmented epithelial (RPE) cells with a high eff

70 are associated with the degeneration of the retinal pigmented epithelial (RPE) layer of the retina.

71 The MFAO-2s protect human neuroblastoma and retinal pigmented epithelial cells against hydroxyl radi

72 fects the secretion of angiogenic factors by retinal pigmented epithelial cells under normoxic, hypox

73 We disrupted CETN2 in human retinal pigmented epithelial cells, and despite having i

74 Here we show that when retinal-pigmented epithelial (RPE1) cells experience mit

75 ich ferritin in the outer retina in-vivo and retinal-pigment-epithelial (RPE) cells in-vitro.

76 is expressed on the basolateral membrane of retinal-pigment-epithelial (RPE) cells, where it mediate

77 To evaluate the features of acute retinal pigment epitheliitis (ARPE) at onset and in the

78 Acute retinal pigment epitheliitis resolved in a sequence of (

79 iar retinal disease, the Martinique crinkled retinal pigment epitheliopathy that begins around the ag

80 totoxicity and genotoxicity studies in human retinal pigment epithelium (ARPE-19) cells.

81 als can stimulate the growth of normal human retinal pigment epithelium (ARPE-19) cells.

82 orders, resembling congenital hypertrophy of retinal pigment epithelium (CHRPE) lesions.

83 tics of combined hamartoma of the retina and retinal pigment epithelium (CHRRPE) involving the macula

84 , we use human induced pluripotent stem cell-retinal pigment epithelium (hiPSC-RPE) derived from pati

85 usen phenotypes, including the occurrence of retinal pigment epithelium (RPE) abnormalities, choroida

86 opathy that begins around the age of 30 with retinal pigment epithelium (RPE) and Bruch's membrane ch

87 pear as hyperreflective deposits between the retinal pigment epithelium (RPE) and Bruch's membrane on

88 nced by increased deposition of C5b-9 in the retinal pigment epithelium (RPE) and choroid.

89 se cause remains elusive, dysfunction of the retinal pigment epithelium (RPE) and dysregulation of co

90 ter segments is an important function of the retinal pigment epithelium (RPE) and it is essential for

91 Histology data show aberrant retinal pigment epithelium (RPE) and late-onset photorec

92 Bestrophin1 (BEST1) is expressed in human retinal pigment epithelium (RPE) and mutations in the BE

93 bi-potential progenitor cells from which the retinal pigment epithelium (RPE) and neural retina fates

94 damage in the diseased retina, damage in the retinal pigment epithelium (RPE) and neural retina from

95 NH surfaces (BMOM, BMOH) and the terminal of retinal pigment epithelium (RPE) and ONH surfaces (RPEM,

96 roduced by neighboring epithelial cells, the retinal pigment epithelium (RPE) and podocytes, respecti

97 he interaction between autophagy impaired in retinal pigment epithelium (RPE) and the responses of ma

98 ations in the morphology and function of the retinal pigment epithelium (RPE) are common features sha

99 nner and outer boundaries of the choroid and retinal pigment epithelium (RPE) as well as the inner re

100 outer retinal disruption and atrophy of the retinal pigment epithelium (RPE) associated with ORT on

101 that photoreceptor atrophy can occur without retinal pigment epithelium (RPE) atrophy and that atroph

102 refied choriocapillaris in correspondence of retinal pigment epithelium (RPE) atrophy in 80% (n = 16)

103 est-corrected visual acuity (BCVA), age, and retinal pigment epithelium (RPE) atrophy were recorded a

104 k of these disorders is the formation of sub-retinal pigment epithelium (RPE) basal deposits.

105 hannel is localized to the apical aspects of retinal pigment epithelium (RPE) cells and contributes t

106 polar cells, mitochondria, Muller cells, and retinal pigment epithelium (RPE) cells and were visualiz

107 Retinal Pigment Epithelium (RPE) cells generated from a

108 o evaluate the intraretinal migration of the retinal pigment epithelium (RPE) cells in age-related ma

109 Cholesterol accumulation beneath the retinal pigment epithelium (RPE) cells is supposed to co

110 h encodes cadherin-3, a protein expressed in retinal pigment epithelium (RPE) cells that may have a k

111 require trophic and functional support from retinal pigment epithelium (RPE) cells.

112 8A is crucial for volume regulation in human retinal pigment epithelium (RPE) cells.

113 s revealed either no abnormalities or foveal retinal pigment epithelium (RPE) changes in 10 and 9 pat

114 eloping murine eye, melanin synthesis in the retinal pigment epithelium (RPE) coincides with neurogen

115 ound TRPV4 expression in the endothelium and retinal pigment epithelium (RPE) components of the BRB,

116 ed macular degeneration and atypical central retinal pigment epithelium (RPE) defects not attributabl

117 ozygous Adamtsl4(tvrm267) mice exhibit focal retinal pigment epithelium (RPE) defects primarily in th

118 al dystrophy, characterised by extensive sub-retinal pigment epithelium (RPE) deposits, RPE atrophy,

119 nal fluid (IRF), subretinal fluid (SRF), sub-retinal pigment epithelium (RPE) fluid, and subretinal t

120 d induced pluripotent stem cells to generate retinal pigment epithelium (RPE) from an individual suff

121 eceptors in three-dimensional optic cups and retinal pigment epithelium (RPE) from iPSCs with this co

122 of pathways necessary for photoreceptor and retinal pigment epithelium (RPE) function is critical to

123 To report on the presence of retinal pigment epithelium (RPE) humps in high myopia, a

124 lipid profiles specifically localized to the retinal pigment epithelium (RPE) in Abca4 (-/-) Stargard

125 Daily, the retinal pigment epithelium (RPE) ingests a bolus of lipi

126 While AMD histopathology involves retinal pigment epithelium (RPE) injury associated with

127 The retinal pigment epithelium (RPE) is a key site of injury

128 The retinal pigment epithelium (RPE) is a monolayer of pigme

129 nd lipid-containing deposits external to the retinal pigment epithelium (RPE) is common in the aging

130 interface between the neural retina and the retinal pigment epithelium (RPE) is critical for several

131 < 0.001-0.03) were: hyperreflective foci and retinal pigment epithelium (RPE) layer atrophy or absenc

132 ber layers (P = 0.024) and diffusely thinned retinal pigment epithelium (RPE) layers (P = 0.009) vers

133 s calculated from the SD-OCT and the area of retinal pigment epithelium (RPE) loss from the FAF.

134 e damage to mitochondrial DNA (mtDNA) in the retinal pigment epithelium (RPE) may play a key role in

135 ated kinase 1/2 (ERK1/2) is increased in the retinal pigment epithelium (RPE) of age-related macular

136 lel clinical phenotypes were observed in the retinal pigment epithelium (RPE) of individuals with but

137 e NLRP3 inflammasome have been implicated in retinal pigment epithelium (RPE) pathology in age-relate

138 s in DPED, estimate of coverage by different retinal pigment epithelium (RPE) phenotypes in the DPED

139 rectly elicit a Wnt/beta-catenin response in retinal pigment epithelium (RPE) progenitors near the op

140 esence of autoantibodies against retinal and retinal pigment epithelium (RPE) proteins.

141 ean (SD) height of 45.3 (36.1) mum above the retinal pigment epithelium (RPE) reference plane that wa

142 absolute measurements of vitreous (VIT) and retinal pigment epithelium (RPE) signal intensities, whi

143 thelial growth factor (VEGF) inhibitors, (2) retinal pigment epithelium (RPE) tear, (3) subretinal he

144 To investigate when retinal pigment epithelium (RPE) tears occur and their a

145 ted to OCT measurement parameters, including retinal pigment epithelium (RPE) thickness, central macu

146 abolite transport is a major function of the retinal pigment epithelium (RPE) to support the neural r

147 tiated, biologically and genetically defined retinal pigment epithelium (RPE) to the diseased human e

148 Retinectomies expose the retinal pigment epithelium (RPE) to the vitreous cavity;

149 In contrast, the canonical retinal pigment epithelium (RPE) visual cycle produces e

150 rmalities in regions with normally appearing retinal pigment epithelium (RPE) were the loss of the PO

151 lated macular degeneration (AMD) affects the retinal pigment epithelium (RPE), a cell monolayer essen

152 te mechanisms that modulate autophagy in the retinal pigment epithelium (RPE), a key site of insult i

153 t), (3) retinal projection through SHRM onto retinal pigment epithelium (RPE), and (4) masking of cho

154 intensities were lower at the photoreceptor, retinal pigment epithelium (RPE), and choroid layers (st

155 tina, resulting from loss of photoreceptors, retinal pigment epithelium (RPE), and underlying chorioc

156 this reisomerization occurs in the adjacent retinal pigment epithelium (RPE), but because ipRGCs are

157 on was found in the photoreceptor-supporting retinal pigment epithelium (RPE), especially in a zone c

158 h the coordinated terminal maturation of the retinal pigment epithelium (RPE), fenestrated choroid en

159 tinoid-containing lipofuscin pigments in the retinal pigment epithelium (RPE), increased oxidative st

160 n abundant membrane-associate protein in the retinal pigment epithelium (RPE), is a key retinoid isom

161 of TGF-beta signaling in the entire eye, the retinal pigment epithelium (RPE), or the vascular endoth

162 assic 'fingerprint' lysosomal storage in the retinal pigment epithelium (RPE), replicating the human

163 educe cytotoxic bisretinoid formation in the retinal pigment epithelium (RPE), which is associated wi

164 ciations of ocular and systemic factors with retinal pigment epithelium (RPE)-Bruch's membrane (BM) c

165 all interfering RNA (siRNA) to transfect the retinal pigment epithelium (RPE)-derived cell line ARPE-

166 The volumes of retinal pigment epithelium (RPE)-drusen complex, RPE-dru

167 ia 9.7, P = .001; SE -2.27 D [SD 4.65]), and retinal pigment epithelium (RPE)-related dystrophies (OR

168 epends on the retinoid cycle in the adjacent retinal pigment epithelium (RPE).

169 espread pigment clumping at the level of the retinal pigment epithelium (RPE).

170 mice lacking caveolin-1 specifically in the retinal pigment epithelium (RPE).

171 ls in a model of chronic degeneration of the retinal pigment epithelium (RPE).

172 (POS) disk membranes, is a major role of the retinal pigment epithelium (RPE).

173 and cone pigment regeneration driven by the retinal pigment epithelium (RPE).

174 the retina, the ciliary margin (CM), and the retinal pigment epithelium (RPE).

175 d epithelial mesenchymal transition (EMT) of retinal pigment epithelium (RPE).

176 may regulate the phagocytosis of OSs by the retinal pigment epithelium (RPE).

177 teristics, especially the involvement of the retinal pigment epithelium (RPE).

178 e (ELM) and mild transient thickening of the retinal pigment epithelium (RPE)/Bruch's complex (Bc).

179 lammatory IL-1beta was markedly increased in retinal pigment epithelium (RPE)/choroid and positively

180 ntally regulated manner in chicken embryonic retinal pigment epithelium (RPE)/choroid in the absence

181 CT B-scans showed 2 distinct profiles of the retinal pigment epithelium (RPE): a slight RPE detachmen

182 n area >/=196350 mum2) and depigmentation of retinal pigment epithelium (slope of -19.17 for the NEI-

183 r displacement of the temporal peripapillary retinal pigment epithelium (tRPE) from its position in c

184 undus photographs were graded for drusen and retinal pigment epithelium abnormalities and were evalua

185 o 17.6% (n = 37) in those 80 years or older, retinal pigment epithelium abnormalities from 4.1% (n =

186 The copresence of medium drusen plus retinal pigment epithelium abnormalities signals a great

187 Retinal pigment epithelium abnormalities, AVLs, neovascu

188 ound the injection site demonstrated diffuse retinal pigment epithelium alterations with dense hard e

189 ion, and position of the CNV relative to the retinal pigment epithelium and Bruch membrane were descr

190 location of vitamin A derivatives across the retinal pigment epithelium and Bruch's membrane, 2 tissu

191 thesis that toll-like receptor activation of retinal pigment epithelium and cellular metabolic switch

192 ipofuscin accumulate in the lysosomes of the retinal pigment epithelium and display cytotoxic effects

193 Quantifying preserved retinal pigment epithelium and EZ areas on FAF and OCT i

194 tors then export the lactate as fuel for the retinal pigment epithelium and for neighboring Muller gl

195 lly if multimodal imaging supports an intact retinal pigment epithelium and inner retina but an abnor

196 insufficient to alter Fpn levels within the retinal pigment epithelium and Muller cells, but may lim

197 ns in the choriocapillaris in the absence of retinal pigment epithelium and outer retinal abnormaliti

198 dal gammadelta T cells in protection against retinal pigment epithelium and retinal injury.

199 s were associated with absence of underlying retinal pigment epithelium and were longer (r = -0.62; 9

200 The atrophic area of the retinal pigment epithelium assessed on the basis of FAF

201 beneath the small irregular elevation of the retinal pigment epithelium at the site of the quiescent

202 , because of the extent of photoreceptor and retinal pigment epithelium atrophy in the macula.

203 data highlight an unrecognised link between retinal pigment epithelium bioenergetic status and tissu

204 Suppression of glucose consumption in the retinal pigment epithelium can increase the amount of gl

205 d by the analysis of LC/MS data from a human retinal pigment epithelium cell line (ARPE-19) grown on

206 y AMD, including Bruchs membrane thickening, retinal pigment epithelium cell loss, retinal functional

207 ascularization and a decrease in mesenchymal retinal pigment epithelium cells in alphaB-crystallin kn

208 Retinal pigment epithelium cells were in the centre, pho

209 Finally, in primary human fetal retinal pigment epithelium cells, ligand binding to TLR2

210 ine, bipolar, horizontal, photoreceptor, and retinal pigment epithelium cells, thus exposing the anat

211 served in the mammalian cochlea and in human retinal pigment epithelium cells.

212 n epithelial-mesenchymal transition (EMT) of retinal pigment epithelium cells.

213 BCA4 mutations lead to clinically detectable retinal pigment epithelium changes remain unclear.

214 f increased autofluorescence as a measure of retinal pigment epithelium damage and lipofuscin accumul

215 d a thicker outer nuclear layer and less sub-retinal pigment epithelium deposit accumulation.

216 l mice had thickening of Bruchs membrane and retinal pigment epithelium dysfunction.

217 e fellow eye, hemorrhage, and absence of sub-retinal pigment epithelium fluid at baseline were associ

218 ntraretinal fluid, subretinal fluid, and sub-retinal pigment epithelium fluid.

219 A uptake across the blood-retinal barrier or retinal pigment epithelium have not been identified.

220 hemorrhages in 2 (17%) and 3 (18%); loss of retinal pigment epithelium in 1 (8%) and 4 (24%); and dr

221 id zone and hyperreflectivity underlying the retinal pigment epithelium in 9 eyes (100%), retinal thi

222 monstrate that Mfsd2a is highly expressed in retinal pigment epithelium in embryonic eye, before the

223 TLR2 was robustly expressed by the retinal pigment epithelium in mouse and human eyes, both

224 f subretinal transplantation of hESC-derived retinal pigment epithelium in nine patients with Stargar

225 ine the incidence of atrophic lesions of the retinal pigment epithelium in patients with Stargardt di

226 lindrical melanosomes forming the remains of retinal pigment epithelium indicates that it is a verteb

227 le of Bruch's membrane, the Bruch's membrane-retinal pigment epithelium interface, or both in the pat

228 Progressive geographic atrophy (GA) of the retinal pigment epithelium leads to loss of central visi

229 gh closely coupled, the results suggest that retinal pigment epithelium loss is more extensive than p

230 inal lamination, neural retinal attenuation, retinal pigment epithelium loss, or hypertrophy was seen

231 the retinal vasculature, optic atrophy, and retinal pigment epithelium loss.

232 rmal amount of pigment granules deposited in retinal pigment epithelium microvilli area and an abnorm

233 at the interface between photoreceptors and retinal pigment epithelium microvilli, a region critical

234 EDF), an antiangiogenic protein, to regulate retinal pigment epithelium migration.

235 arget of TLR2 signaling, was detected in the retinal pigment epithelium of human eyes, particularly i

236 point to subnormal lipofuscin levels in the retinal pigment epithelium or, alternatively, limitation

237 inal hyperreflective foci represent cells of retinal pigment epithelium origin that are similar to th

238 ted with acquired vitelliform lesions are of retinal pigment epithelium origin, and the natural cours

239 PGS2 when cultured with interleukin-33-rich retinal pigment epithelium supernatant.

240 Retinal pigment epithelium tears act differently dependi

241 We excluded 5 eyes from analysis (4 had retinal pigment epithelium tears, and 1 had a laser scar

242 from the choroidal blood passes through the retinal pigment epithelium to the retina where photorece

243 bilateral soft drusen and depigmentation of retinal pigment epithelium was associated with substanti

244 1% intraretinal, 38% subretinal, and 36% sub-retinal pigment epithelium).

245 se was composed of 6 layered components: (1) retinal pigment epithelium, (2) basal laminar deposits,

246 xcavation involving the neurosensory retina, retinal pigment epithelium, and choroid in 4 eyes (44%).

247 able degrees of atrophy of the outer retina, retinal pigment epithelium, and choroid, with outer reti

248 extent of structural alterations of the CC, retinal pigment epithelium, and photoreceptors with mult

249 quantitative characteristics of the choroid, retinal pigment epithelium, and retina were compared bet

250 ion, likely by promoting inflammation of the retinal pigment epithelium, and validate TLR2 as a novel

251 ST2 was highly expressed in retinal pigment epithelium, choroidal mast cells, and ch

252 angles, loss of pigment and thinning of the retinal pigment epithelium, choroidal thinning, undiffer

253 ansdifferentiation of the dorsal and ventral retinal pigment epithelium, defective optic cup peripher

254 ccelerated accumulation of lipofuscin in the retinal pigment epithelium, degeneration of the neuroret

255 nct morphologies arranged in layers, forming retinal pigment epithelium, is a synapomorphy of vertebr

256 ies, including congenital hypertrophy of the retinal pigment epithelium, ora serrata pearl, TCD, cyst

257 pment of ischemic infarction of the choroid, retinal pigment epithelium, outer part of the retina and

258 g vortex vein, congenital hypertrophy of the retinal pigment epithelium, pars plana, ora serrata pear

259 Loss of retinal pigment epithelium, the presence of a thin choro

260 rystal mutant lacks pigmentation also in the retinal pigment epithelium, therefore enabling optical a

261 Retinal pigment epithelium-BM thickness, as measured by

262 nce tomography (OCT) revealed a split in the retinal pigment epithelium-Bruch membrane band.

263 ning of the cone outer segment closer to the retinal pigment epithelium.

264 in pigment cells, including melanocytes and retinal pigment epithelium.

265 glia cells, and the basolateral side of the retinal pigment epithelium.

266 hed chromophores and recycling in the nearby retinal pigment epithelium.

267 ar surface ectoderm, lens, neuro-retina, and retinal pigment epithelium.

268 generalized dysfunction at the level of the retinal pigment epithelium.

269 nted when sFlt-1 expression is attenuated in retinal pigment epithelium.

270 and infiltrating myeloid cells but not from retinal pigment epithelium.

271 particularly toxic to photoreceptors and/or retinal pigment epithelium.

272 s </=325 mum or >/=425 mum, and elevation of retinal pigment epithelium.

273 terized by macular atrophy and flecks in the retinal pigment epithelium.

274 etabolite carrier between the retina and the retinal pigment epithelium.

275 al pigmentation consistent with transplanted retinal pigment epithelium.

276 of 11-cis-retinyl esters (11-REs) within the retinal pigment epithelium.

277 e can suppress consumption of glucose by the retinal pigment epithelium.

278 istent with PVR, and reactive changes in the retinal pigment epithelium.

279 on, optic nerve head pallor, and mottling of retinal pigment epithelium.

280 tween the interdigitation zone and an intact retinal pigment epithelium.

281 alized to CNV-associated macrophages and the retinal pigment epithelium/choroid complex.

282 nt component 3 and factor B in plasma and in retinal pigment epithelium/choroid/sclera, establishing

283 mophore through a series of reactions in the retinal pigmented epithelium (RPE visual cycle).

284 elated macular degeneration characterized by retinal pigmented epithelium (RPE) death; the RPE also e

285 The retinal pigmented epithelium (RPE) forms the outer blood

286 Accumulation of bis-retinoids in the retinal pigmented epithelium (RPE) is a hallmark of agin

287 One of the major biological functions of the retinal pigmented epithelium (RPE) is the clearance of s

288 ession, we delivered a wild-type Mfrp to the retinal pigmented epithelium (RPE) of Mfrp (rd6) /Mfrp (

289 y both the intraretinal visual cycle and the retinal pigmented epithelium (RPE) visual cycle.

290 alysis revealed predominant up-regulation of retinal pigmented epithelium (RPE)-specific genes associ

291 ns that occur in photoreceptor cells and the retinal pigmented epithelium (RPE).

292 iRNA)-processing enzyme DICER1 in the mature retinal pigmented epithelium (RPE).

293 pecialized phagocytes: Sertoli cells and the retinal pigmented epithelium (RPE).

294 decreased levels of CFH led to increased sub-retinal pigmented epithelium (sub-RPE) deposit formation

295 raphy confirmed that these areas had loss of retinal pigmented epithelium and ellipsoids zones, with

296 IS organelles in the OS region and abnormal retinal pigmented epithelium cells.

297 gic functions of photoreceptor cells and the retinal pigmented epithelium necessitate precise gene re

298 ated retina preparation after removal of the retinal pigmented epithelium.

299 ge, indicative of pathological events in the retinal pigmented epithelium.

300 sis of drusen size, type and area, increased retinal pigment, retinal pigment epithelial depigmentati