ライフサイエンスコーパス: retinoid X receptor alpha

1 ructures of the thyroid-hormone receptor and retinoid X receptor alpha.

2 strated that PPARalpha bound FARE-1 with the retinoid X receptor alpha.

3 receptor, retinoic acid receptor alpha, and retinoid X receptor alpha.

4 d miR193 expression via transcription factor retinoid X receptor alpha.

5 eptor, constitutive androstane receptor, and retinoid X receptor alpha.

6 nteract with retinoic acid receptor-gamma or retinoid X receptor-alpha.

7 Although forced expression of PPAR gamma and retinoid X receptor alpha activates the enhancer in HIB-

8 gand-dependent transcriptional activation of retinoid X receptor alpha and to a lesser effect on PPAR

9 Nuclear receptors including retinoid X receptor-alpha and peroxisome proliferator-ac

10 homodimerization and heterodimerization with retinoid X receptor alpha, and different dimerization in

11 In gel mobility shift experiments, TRalpha, retinoid X receptor-alpha, and mature SREBP-1 formed a t

12 AAT/enhancer binding protein-alpha, receptor retinoid X receptor-alpha, and peroxisome profilerator-a

13 receptors (RARs) alpha, beta, and gamma; and retinoid X receptors alpha, beta, and gamma but were not

14 y shift assays demonstrate that LXRalpha and retinoid X receptor alpha bind to the two LXREs in intro

15 Ethanol feeding decreased PPARalpha/retinoid X receptor alpha binding in electrophoretic mob

16 capable of heterodimerizing with that of the retinoid X receptor alpha but not with that of other rec

17 Ralpha, induced the recruitment of PPARalpha:retinoid x receptor alpha, but not PPARgamma coactivator

18 hereby implicating activation of a PPARgamma-retinoid X receptor alpha complex.

19 riments, these motifs specifically bound VDR.retinoid X receptor-alpha complexes.

20 d 14, and normal melanocyte distribution and retinoid X receptor-alpha expression.

21 istent with this suggestion, it appears that retinoid X receptor alpha/farnesoid X receptor alpha and

22 PPARalpha/retinoid X receptor alpha formed specific complexes with

23 interact with the ligand-binding domains of retinoid X receptor alpha, glucocorticoid receptor, and

24 , such as steroid receptor co-activator 1 or retinoid X receptor alpha, had no effect on S14CAT PUFA

25 An in vitro translated CAR acting as a retinoid X receptor alpha heterodimer binds directly to

26 ic mobility shift assays showed that the PXR-retinoid X receptor alpha heterodimer binds to the DR3-2

27 specific target genes.The vitamin D receptor/retinoid X receptor-alpha heterodimer (VDRRXRalpha) regu

28 The vitamin D receptor/retinoid X receptor-alpha heterodimer (VDRRXRalpha) regu

29 ferator responsiveness via the PPARgamma and retinoid X receptor-alpha heterodimer.

30 ited the DNA binding activity of a PPARgamma/retinoid X receptor alpha heterodimeric complex.

31 X receptor (FXR) via a direct binding of FXR/retinoid X receptor alpha heterodimers to a highly conse

32 Human retinoid X receptor alpha (hRXRalpha) plays a critical r

33 VDR but not retinoic acid receptor alpha and retinoid X receptor alpha in yeast.

34 stored the DNA binding activity of PPARalpha/retinoid X receptor alpha, induced mRNA levels of PPARal

35 al cardiac defects such as those seen in the retinoid X receptor alpha knockout (Rxra(-/-)) mouse.

36 Cotreatment with a retinoid X receptor alpha ligand, 9-cis-retinoic acid, d

37 tric interaction of 9-cis-retinoic acid with retinoid X receptor alpha monomers.

38 d to this site as a monomer, because neither retinoid X receptor alpha nor retinoid X receptor beta a

39 form v-ErbA homodimers and heterodimers with retinoid X receptor alpha on differently oriented core m

40 expression of retinoic acid receptor gamma, retinoid X receptor alpha, or both.

41 in D receptor, retinoic acid receptor alpha, retinoid X receptor alpha, peroxisome proliferation-acti

42 e receptors, hepatocyte nuclear factor 4 and retinoid X receptor alpha plus peroxisome proliferator-a

43 itation studies confirmed the recruitment of retinoid X receptor alpha, PPARalpha, and PGC1alpha on t

44 arginal interactions with estrogen receptor, retinoid X receptor alpha, PPARalpha, and PPARgamma.

45 In vivo, RA receptor beta and retinoid X receptor alpha preferentially interacted with

46 erator-activated receptor gamma (PPARgamma), retinoid X receptor alpha proteins, and all-trans retino

47 Heterodimerization of PPARalpha to the retinoid X receptor-alpha resulted in even larger increa

48 Surprisingly, occupancies of FXR, retinoid X receptor alpha, RNA polymerase II, and epigen

49 to be differentially regulated by the murine retinoid X receptor alpha (RXR alpha) as compared with R

50 ctivated receptor gamma (PPAR gamma) and the retinoid X receptor alpha (RXR alpha) form a heterodimer

51 inoic acid-dependent interaction with a VP16-retinoid X receptor alpha (RXR alpha) fusion.

52 Retinoid X receptor alpha (RXR alpha) localized througho

53 ne expression, the regulatory effects of the retinoid X receptor alpha (RXR alpha) on atrial naturiet

54 s hepatocyte nuclear factor 4 (HNF4) and the retinoid X receptor alpha (RXR alpha) plus peroxisome pr

55 receptor (VDR) and its heterodimeric partner retinoid X receptor alpha (RXR alpha) specifically bound

56 ide substitutions prevent the binding of the retinoid X receptor alpha (RXR alpha)-peroxisome prolife

57 receptor (VDR) acts as heterodimer with the retinoid X receptor alpha (RXR) to control transcription

58 -2 motif of CAR3 and is markedly enhanced by retinoid X receptor-alpha (RXR) cotransfection.

59 r expression of vitamin D receptor (VDR) and retinoid X receptor-alpha (RXR) has not been investigate

60 eptor gamma (PPAR-gamma) and its co-receptor retinoid-X-receptor alpha (RXR-alpha).

61 We cloned the nuclear receptor retinoid X receptor-alpha(RXR-alpha) as an IGFBP-3 prote

62 kely to be directly NRF2-dependent including retinoid X receptor alpha (RXRA).

63 In cohort 1, retinoid X receptor-alpha (RXRA) chr9:136355885+ and end

64 Association of the retinoid X receptor-alpha (RXRA) coreceptor to PML/RARA

65 port that Nuclear receptor-related 1 (Nurr1):Retinoid X receptor alpha (RXRalpha) activation has a do

66 three closely related human NRs--HNF4alpha, retinoid X receptor alpha (RXRalpha) and COUPTF2--reveal

67 way that strongly inhibits the expression of retinoid X receptor alpha (RXRalpha) and suppresses the

68 Signaling pathways regulated by retinoid x receptor alpha (RXRalpha) are involved in hep

69 tor activated receptor-gamma (PPARgamma) and retinoid X receptor alpha (RXRalpha) complex was found t

70 ) lymphocytes is associated with the loss of retinoid X receptor alpha (RXRalpha) expression.

71 , we used the Cre-loxP system to disrupt the retinoid X receptor alpha (RXRalpha) gene specifically i

72 ferator-activated receptor gamma (PPARgamma):retinoid X receptor alpha (RXRalpha) heterodimer.

73 nal activation in the context of a PPARalpha.retinoid X receptor alpha (RXRalpha) heterodimeric compl

74 Although the DeltaNCARs maintain full retinoid X receptor alpha (RXRalpha) heterodimerization

75 egulated by activators of both PPARgamma and retinoid X receptor alpha (RXRalpha) in a synergistic ma

76 ns that serve as interacting partners of the retinoid X receptor alpha (RXRalpha) in heart, DNA-prote

77 sactivation of BSEP and SHP promoters by FXR/retinoid X receptor alpha (RXRalpha) in HepG2 cells.

78 Retinoid X receptor alpha (RXRalpha) plays a pivotal rol

79 r partner to class II nuclear receptors, the retinoid X receptor alpha (RXRalpha) plays a vital physi

80 93T, it was possible to demonstrate that the retinoid X receptor alpha (RXRalpha) plus its ligand can

81 epatocyte nuclear factor 4alpha (HNF4alpha), retinoid X receptor alpha (RXRalpha) plus peroxisome pro

82 ediated by hepatocyte nuclear factor 4alpha, retinoid X receptor alpha (RXRalpha) plus peroxisome pro

83 tocyte nuclear factor 4alpha (HNF4alpha) and retinoid X receptor alpha (RXRalpha) plus peroxisome pro

84 ptors hepatocyte nuclear factor 4 (HNF4) and retinoid X receptor alpha (RXRalpha) plus peroxisome pro

85 Retinoid x receptor alpha (RXRalpha) serves as an active

86 tor-activated receptor-alpha (PPARalpha) and retinoid X receptor alpha (RXRalpha) stimulate the expre

87 s predicted to interact efficiently with VDR-retinoid X receptor alpha (RXRalpha) was identified in s

88 pharmacologically perturbed the activity of retinoid X receptor alpha (RXRalpha), a key hub within t

89 The retinoid X receptor alpha (RXRalpha), a key nuclear rece

90 We have examined the role of hepatocyte retinoid X receptor alpha (RXRalpha), an essential partn

91 ctive homodimers to active heterodimers with retinoid X receptor alpha (RXRalpha), and phosphorylatio

92 depends on vitamin A signals mediated by the retinoid X receptor alpha (RXRalpha), as the systemic mu

93 Retinoid X receptor alpha (RXRalpha), functioning as eit

94 rmone receptor TRalpha1, in combination with retinoid X receptor alpha (RXRalpha), is specifically bo

95 on of RARbeta, but not RARalpha, RARgamma or retinoid X receptor alpha (RXRalpha), on a variety of RA

96 interact in an agonist-dependent manner with retinoid X receptor alpha (RXRalpha), suggesting that th

97 Pbeta), forkhead box protein A2 (FOXA2), and retinoid X receptor alpha (RXRalpha), were markedly decr

98 ln275, Arg316 and Arg371 in nuclear receptor retinoid X receptor alpha (RXRalpha), where berberine co

99 it is very similar in amino acid sequence to retinoid X receptor alpha (RXRalpha), which heterodimeri

100 xisome proliferator-activated receptor alpha-retinoid X receptor alpha (RXRalpha), with which PGC-1be

101 retinoic acid receptor alpha (RARalpha) and retinoid X receptor alpha (RXRalpha).

102 ncer cell apoptosis mediated via the nuclear retinoid X receptor alpha (RXRalpha).

103 oblastoma tumor suppressor protein (pRb) and retinoid X receptor alpha (RXRalpha).

104 retinoic acid receptor gamma (RARgamma) and retinoid X receptor alpha (RXRalpha).

105 Chinese hamster ovary cells transfected with retinoid X receptor alpha (RXRalpha)/FXR, only chenodeox

106 onstitutive androstane receptor (CAR, NR1I3)/retinoid X receptor alpha (RXRalpha, NR2B1) heterodimer

107 ity to this element as heterodimers with the retinoid X receptor alpha (RXRalpha, NR2B1).

108 Retinoid X receptor-alpha (RXRalpha) binds to DNA either

109 ing protein-alpha (Cebpalpha), Cebpbeta, and retinoid x receptor-alpha (Rxralpha) compared with untre

110 The human vitamin D receptor (VDR) and retinoid X receptor-alpha (RXRalpha) modulate gene activ

111 RARalpha formed heterodimers with endogenous retinoid X receptor-alpha (RXRalpha) over RA response el

112 how here that keratinocytic nuclear receptor retinoid X receptor-alpha (RXRalpha) regulates mouse ker

113 In addition, coexpression of retinoid X receptor-alpha (RXRalpha) resulted in nuclear

114 brate drugs were abrogated in the absence of retinoid X receptor-alpha (RXRalpha), a molecule known t

115 n availability as hepatic nuclear PPARgamma, retinoid X receptor-alpha (RXRalpha), and PPARgamma/RXRa

116 roach designed to identify novel ligands for retinoid X receptor-alpha (RXRalpha).

117 ing binding to other molecules including the retinoid X receptor-alpha (RXRalpha).

118 dogenous PPARgamma together with its partner retinoid-X receptor alpha (RXRalpha).

119 Retinoid X receptor alpha [RXRalpha; nuclear receptor (N

120 pha, but were decreased in mice deficient in retinoid X receptor-alpha, the major heterodimerization

121 s, which includes the progesterone receptor, retinoid X receptor alpha, thyroid hormone receptor beta

122 e ability to significantly activate RARs and retinoid X receptor alpha to initiate (TREpal)(2)-tk-CAT

123 ranscriptional regulation via binding of VDR.retinoid X receptor-alpha to discrete DNA motifs.

124 tinoids, MM11453 does not behave as a RAR or retinoid X receptor alpha transcriptional agonist.

125 mation weight matrix for vitamin D3 receptor/retinoid X receptor alpha (VDR/RXRalpha) binding sites w

126 me proliferator-activated receptor gamma and retinoid-X-receptor alpha, which is further stimulated b

127 The interaction of retinoid X receptor alpha with 9-cis-retinoic acid was s

128 e by combining antagonists for PPARgamma and retinoid X receptor alpha with selective estrogen recept