ライフサイエンスコーパス: retinol

1 th minimal increases in preformed vitamin A (retinol).

2 pha-1-acid glycoprotein (AGP), ferritin, and retinol.

3 ol to trigger release and internalization of retinol.

4 brospinal fluid transporter of thyroxine and retinol.

5 ene concentrations but did not improve serum retinol.

6 omerase in Muller cells, appears to be 9-cis retinol.

7 SDR9C7 is an enzyme to convert retinal into retinol.

8 the percentages of the explained variance of retinol.

9 converts all-trans-retinyl ester into 11-cis-retinol.

10 ts were reversible after treatment with free retinol.

11 lyzes the reduction of retinaldehyde back to retinol.

12 rved with 3,3-, 4,4-, and 3,3,4,4-deuterated retinol.

13 which catalyzes equilibrium isomerization of retinol.

14 reduced metabolism of both retinaldehyde and retinol.

15 rophobic binding pocket that can accommodate retinol.

16 (control), both containing 1.8 muCi of [(3)H]retinol.

17 ns-retinol visual chromophore back to 11-cis-retinol.

18 te and transported in the blood analogous to retinol.

19 BP4) impede ocular uptake of serum all-trans retinol (1) and have been shown to reduce cytotoxic bisr

20 izemeal clusters (P < 0.001), but mean serum retinol (1.00 +/- 0.33 mumol/L overall) and deficiency p

21 alysis of the fat-soluble vitamins all-trans retinol (A), 25-hydroxyvitamin D2, 25-hydroxyvitamin D3,

22 t converts all-trans-retinyl ester to 11-cis-retinol, a key reaction in the retinoid visual cycle.

23 Serum retinol-a VAD marker-increases in kidney disease and dec

24 corbic acid, total phenols, carotenoids, and Retinol Activity Equivalent (RAE) were measured.

25 t a rich source of provitamin A (ca. 124 mug retinol-activity-equivalents/100g pulp, FW).

26 We show here that lecithin:retinol acyl transferase (LRAT), which catalyzes esterif

27 Mutations in RPE65 or lecithin-retinol acyltransferase (LRAT) disrupt 11-cis-retinal sy

28 Lecithin:retinol acyltransferase (LRAT) is the enzyme that traps

29 on and colocalization of RPE65 with lecithin:retinol acyltransferase (LRAT) that provides the hydroph

30 Lecithin-retinol acyltransferase (LRAT)-deficient mice and P23H m

31 acts in conjunction with the enzyme lecithin:retinol acyltransferase to facilitate retinol uptake in

32 oximately 2-fold higher vitamin A (all-trans-retinol (all-trans-ROL)) in the neural retina following

33 we have imaged the fluorescence of all-trans-retinol, all-trans-retinal, and lipofuscin precursors in

34 ions of the concentrations of 7 carotenoids, retinol, alpha-tocopherol, and gamma-tocopherol with ris

35 ene, lutein, zeaxanthin, beta-cryptoxanthin, retinol, alpha-tocopherol, gamma-tocopherol, and vitamin

36 l on hip fracture or any interaction between retinol and 25-hydroxyvitamin D.

37 ids were analyzed by gas chromatography, and retinol and alpha-, and gamma-tocopherol by liquid chrom

38 9c, 11tCLA, SigmaCLA, PUFA, omega3, omega6, retinol and alpha-tocopherol.

39 ined the associations between maternal serum retinol and beta-carotene concentrations during late pre

40 Maternal serum retinol and beta-carotene concentrations had differing a

41 In late pregnancy, maternal serum retinol and beta-carotene concentrations were measured.

42 flammation, baseline serum concentrations of retinol and beta-carotene, and stratified design.

43 ing pairs had measurements of maternal serum retinol and beta-carotene, respectively.

44 her investigation of the effects of maternal retinol and carotenoid status on offspring bone developm

45 patients with PH-IPF or PH-COPD revealed the retinol and extracellular matrix (ECM) receptor interact

46 We aimed to study the association between s-retinol and hip fracture and whether high s-retinol may

47 tin in the serum would reduce serum RBP4 and retinol and inhibit bisretinoid formation.

48 e cancer risk was positively associated with retinol and inversely associated with alpha-tocopherol,

49 ype PNPLA3 hydrolyzes retinyl palmitate into retinol and palmitic acid.

50 ck of changes in retinaldehyde conversion to retinol and retinoic acid in the cells overexpressing DH

51 A systematic analysis of tissue retinol and retinyl ester levels was performed with HPLC

52 os have approximately 4-fold lower levels of retinol and retinyl esters, but only slightly elevated l

53 esized primarily in the liver where it binds retinol and transports it to tissues throughout the body

54 vitamin A status (retinol-binding protein or retinol)] and >/=1 biomarker of inflammation (alpha-1-ac

55 etinol to 3,4-dehydroretinol, 4-hydroxy (OH) retinol, and 3-OH retinol in a 100:3:2 ratio.

56 augmented proliferation and migration, lower retinol, and abolished retinoid X receptor/retinoid A re

57 all-trans and 11-cis isomers of retinal and retinol, and this facilitates their transport between ph

58 vel PKCdelta signaling pathway that requires retinol as a metabolic cofactor and is involved in the r

59 ociations of T2D and hypertension with serum retinol as well as the importance of kidney function and

60 Its expression is regulated by retinol availability and insulin, and increased PNPLA3 e

61 ntified 63 metabolites associated with serum retinol below the Bonferroni-corrected P-value (p < 5.3

62 but not T2D, was positively associated with retinol (beta: 0.12; 95% CI: 0.08, 0.17), adjusted for a

63 A decrease in serum retinol, beta-carotene, and RBP4 is associated with earl

64 levels were inversely correlated with serum retinol, beta-carotene, and RBP4.

65 and after the intervention to measure serum retinol, beta-carotene, C-reactive protein, and alpha1-a

66 d efficiently, causing repeated recycling of retinol between plasma and tissues (541 compared with 5

67 Vitamin A bound to retinol binding protein 4 (RBP4) constitutes the major t

68 L-HDLs showed a reduced content of lipocalin retinol binding protein 4 and apolipoprotein M and in th

69 Here we examined the role of zebrafish retinol binding protein receptor 2 (Rbpr2) for RBP4-reti

70 s (ferritin, serum transferrin receptor, and retinol binding protein) in settings of prevalent inflam

71 d missense mutations in RBP4, encoding serum retinol binding protein, in three families with eye malf

72 luded height for age at 10 weeks, vitamin D, retinol binding protein, maternal education, household i

73 Here we show that mouse and human SAAs are retinol binding proteins.

74 The disease mutations greatly reduce retinol binding to RBP, yet paradoxically increase the a

75 5 ng/mL or 32 pmol/L), vitamin A deficiency (retinol-binding protein <14.7 mug/mL or 0.70 mumol/L) an

76 We crossed mice overexpressing human retinol-binding protein (hRBP) under the muscle creatine

77 Binding of the natural ligands thyroxine or retinol-binding protein (RBP) by Ser52Pro variant TTR st

78 Retinol-binding protein (RBP) is often used in populatio

79 Retinol-binding protein (RBP) is the sole specific carri

80 min A, retinol, circulates in blood bound to retinol-binding protein (RBP).

81 on retinyl esters (CM-REs), retinol bound to retinol-binding protein (RBP-ROH), and total retinol wer

82 orage, and metabolism of retinoids, cellular retinol-binding protein 1 (CRBP1) is essential for traff

83 in, and desmin, and negatively with cellular retinol-binding protein 1 and matrix metalloproteinase 2

84 eased markers of dedifferentiation, cellular retinol-binding protein 1, and matrix metalloproteinase

85 uced by immunization with interphotoreceptor retinol-binding protein 1177-1191 peptide were treated b

86 erations in the vitamin A-transport proteins retinol-binding protein 4 (RBP4) and prealbumin.

87 Elevated levels of serum retinol-binding protein 4 (RBP4) contribute to insulin r

88 onsiderable evidence that both retinoids and retinol-binding protein 4 (RBP4) contribute to the devel

89 Retinol-binding protein 4 (RBP4) has been implicated as

90 Antagonists of retinol-binding protein 4 (RBP4) impede ocular uptake of

91 Serum retinol-binding protein 4 (RBP4) is the sole specific tr

92 in (TTR) is a critical determinant of plasma retinol-binding protein 4 (RBP4) levels.

93 onizing the retinol-dependent interaction of retinol-binding protein 4 (RBP4) with transthyretin in t

94 To examine whether serum retinol-binding protein 4 (RBP4), an endogenous TTR liga

95 Similarly, serum levels of retinol-binding protein 4 and retinoids were significant

96 adipocytokines (interleukin-6, adiponectin, retinol-binding protein 4) or soluble intercellular adhe

97 variate analysis) determinant of circulating retinol-binding protein 4, a reliable proxy for retinol

98 bin concentration or serum concentrations of retinol-binding protein and prealbumin.

99 y using high-pressure liquid chromatography, retinol-binding protein by using ELISA, and alanine amin

100 Ratios of serum retinol to retinol-binding protein did not deviate from 1.0, which

101 le transferrin receptor or vitamin A status (retinol-binding protein or retinol)] and >/=1 biomarker

102 Our aim was to elucidate the role of the retinol-binding protein receptor STRA6, mediating cellul

103 usly quantifying iron (ferritin), vitamin A (retinol-binding protein), and inflammation (C-reactive p

104 n and serum concentrations of beta-carotene, retinol-binding protein, and prealbumin.

105 The Stra6 protein binds the serum retinol-binding protein, RBP4, and acts in conjunction w

106 of the lipophilic vitamin is mediated by the retinol-binding protein, RBP4.

107 retinoid-binding protein (IRBP) or cellular retinol-binding protein, suggesting that peropsin plays

108 ol), and proximal renal tubular dysfunction (retinol-binding protein/creatinine ratio >2.93mug/mmol a

109 it upon ligand binding by mammalian cellular retinol-binding proteins.

110 hibitor families, as well as fatty acid- and retinol-binding proteins.

111 sfer of chylomicron retinyl esters (CM-REs), retinol bound to retinol-binding protein (RBP-ROH), and

112 is reduced by exogenously applied all-trans retinol but not all-trans retinal.

113 ed associations of T2D and hypertension with retinol by linear regression and calculated the contribu

114 metabolism, which enables cellular uptake of retinol by maintaining an inward-directed concentration

115 all-trans isomer and reduction to all-trans-retinol by RDH can prevent the accumulation of excess 11

116 Vitamin A, retinol, circulates in blood bound to retinol-binding pr

117 The baseline prevalence of serum retinol concentration <0.7 mumol/L and inflammation was

118 ed by ultra-high performance LC-MS/GC-MS and retinol concentration (from HPLC) using linear regressio

119 yellow cassava led to modest gains in serum retinol concentration and a large increase in beta-carot

120 bolite concentrations per unit difference in retinol concentration as standardized beta-coefficients

121 eta-carotene supplementation increased serum retinol concentration by 0.04 mumol/L (95% CI: 0.00, 0.0

122 ources from 83 countries with measured serum retinol concentration data.

123 effect of consuming yellow cassava on serum retinol concentration in Kenyan schoolchildren with marg

124 Serum retinol concentration is associated with circulating met

125 of vitamin A deficiency, defined as a serum retinol concentration lower than 0.70 mumol/L.

126 The primary outcome was serum retinol concentration; prespecified secondary outcomes w

127 18,446 had significantly higher circulating retinol concentrations compared with control mice.

128 there tended to be an increased risk at low retinol concentrations, which was attenuated after contr

129 fects hepatic glucose sensing independent of retinol conversion.

130 Our data show that kidneys respond to retinol deficiency by differential Stra6 promoter usage,

131 Gestational vitamin A (retinol) deficiency poses a risk for ocular birth defect

132 The microsomal retinol dehydrogenase (RDH11) and cytosolic soluble alde

133 nstrates that DHRS3 requires the presence of retinol dehydrogenase 10 (RDH10) to display its full cat

134 Here, we sought to determine whether retinol dehydrogenase 10 (RDH10), upregulated in rod/con

135 of at least two subunits of NAD(+)-dependent retinol dehydrogenase 10 (RDH10), which catalyzes the ox

136 y, we discovered that mice with mutations in retinol dehydrogenase 10 (Rdh10), which perturbs Vitamin

137 B1 (Cyp26b1), which results in excess RA, or retinol dehydrogenase 10 (Rdh10), which results in RA de

138 , c.C199T:p.R67* and c.C322T:p.R108*, in the retinol dehydrogenase 11 (RDH11) gene, resulting in a no

139 eport that two chromophore binding proteins, retinol dehydrogenase 8 (RDH8) and photoreceptor-specifi

140 e roles of two chromophore-binding proteins, retinol dehydrogenase 8 (RDH8) and photoreceptor-specifi

141 brane-associated retinaldehyde reductase and retinol dehydrogenase activities are decreased by approx

142 In turn, the retinol dehydrogenase activity of RDH10 is reciprocally

143 Here we describe a third retinol dehydrogenase in the RPE, RDH10, which can produ

144 release, all-trans-retinal is reduced by the retinol dehydrogenase RDH8 to all-trans-retinol in an NA

145 esis at the rate-limiting step, catalyzed by retinol dehydrogenases (RDH).

146 Compensatory expression of other retinol dehydrogenases was observed in both Rdh5(-/-) an

147 plished by a family of enzymes termed 11-cis-retinol dehydrogenases, including RDH5 and RDH11.

148 Compounds antagonizing the retinol-dependent interaction of retinol-binding protein

149 ional analytic methods do not separate alpha-retinol derivatives from active retinol.This study aimed

150 Retinol determined by high-pressure liquid chromatograph

151 rediagnostic sera from the Beta-Carotene and Retinol Efficacy Trial (CARET) study.

152 RA or retinol enhances 5hmC production in naive embryonic stem

153 e estimated total daily intake of vitamin A (retinol equivalents) and vitamin E (alpha-tocopherol equ

154 ations of choline, betaine, dimethylglycine, retinol, essential fatty acids, methionine, dimethylamin

155 as triacylglycerol, cholesterol esters, and retinol esters; esterified to form membrane phospholipid

156 ollowing a bleach and to use exogenous 9-cis retinol for pigment regeneration, suggesting that access

157 0 and transgenic rods were unable to use cis-retinol for pigment regeneration.

158 rotene was detected in the dairy samples but retinol (free or esterified), derived from the intake of

159 otein that serves a dual role: it transports retinol from extracellular RBP into cells and it transdu

160 RBP normally delivers retinol from hepatic stores to peripheral tissues, inclu

161 We found that IRBP removes all-trans-retinol from individual rod photoreceptors in a concentr

162 serves a dual role: it mediates transport of retinol from RBP into cells, and it functions as a cytok

163 s the enzyme that traps vitamin A (all-trans-retinol) from the circulation and photoreceptor cells to

164 takes and serum concentrations of retinol (s-retinol) have been observed in epidemiologic studies.

165 owest compared with the middle quintile of s-retinol (HR: 1.41; 95% CI: 1.09, 1.82) adjusted for sex

166 droretinol, 4-hydroxy (OH) retinol, and 3-OH retinol in a 100:3:2 ratio.

167 e have decreased levels of retinoic acid and retinol in adipose tissue.

168 the retinol dehydrogenase RDH8 to all-trans-retinol in an NADPH-dependent reaction.

169 The aim is to investigate whether serum retinol in an un-supplemented state is associated with l

170 oval increased atRA biosynthesis 4-fold from retinol in HepG2 cells, whereas dominant-negative FoxO1

171 Higher maternal serum retinol in late pregnancy was associated with lower offs

172 A higher risk of breast cancer was found for retinol in relation to ER-/progesterone receptor-negativ

173 ted in lower levels of all-trans-retinal and retinol in rod outer segments following light exposure.

174 Thus, the interpretation of serum retinol in sub-Saharan Africa should account for hyperte

175 ) is the sole specific transport protein for retinol in the blood, but it is also an adipokine with r

176 be underestimated because of increased serum retinol in the context of kidney dysfunction.

177 The role of retinol in the prevention of multifactorial chronic dise

178 f all-trans-retinyl ester (atRE) into 11-cis-retinol in the retinal visual cycle.

179 ith nanomolar affinity, were associated with retinol in vivo, and limited the bacterial burden in tis

180 class pathways were strongly associated with retinol, including amino acids (p = 1.6 x 10(-10)), lipi

181 have relevance to the biological actions of retinol, including its role in carcinogenesis.

182 the blood, but it is also an adipokine with retinol-independent, proinflammatory activity associated

183 by retinoic acid 6 (STRA6), which transports retinol into cells.

184 d (as compared with other fatty acids).alpha-Retinol is esterified in the enterocyte and transported

185 In the eye, uptake of RBP4-retinol is mediated by the receptor Stra6, whereas the r

186 This 11-cis-retinol is oxidized selectively in cones to the 11-cis-r

187 Cellular uptake of vitamin A (retinol) is essential for many biological functions.

188 zation of all-trans-retinyl esters to 11-cis-retinol, is also the isomerase enzyme responsible for th

189 e bleaching in rod photoreceptors, all-trans retinol, is part of a feedback loop that increases the s

190 The retinol isomerase for this noncanonical pathway is dihyd

191 eramide desaturase-1, the putative all-trans retinol isomerase in Muller cells, appears to be 9-cis r

192 We found that cone density in retinol isomerase RPE65-deficient and cone photoreceptor

193 Retinol isomerase RPE65-deficient mice [a model of Leber

194 e evolution of the BCO-related outlier RPE65 retinol isomerase, an enzyme that does not utilize carot

195 igh liver retinol stores determined by using retinol isotope dilution (RID).

196 ffs of <0.1 mumol VA/g liver with the use of retinol isotope dilution and <0.7 mumol/L for SR concent

197 The paired (13)C-retinol isotope dilution test, a sensitive biomarker for

198 d by mothers fed a VA-marginal diet (0.35 mg retinol/kg diet) and treated on postnatal day 4 with an

199 ly, Cyp1b1 could generate retinoic acid from retinol leading to cell-autonomous induction of the barr

200 igen-positive persons who also had low serum retinol levels (for detectable levels vs. undetectable l

201 on in males, whereas in autumn, it increased retinol levels but reduced coloration in both genders.

202 inol-binding protein 4, a reliable proxy for retinol levels in humans.

203 no significant differences in plasma RBP4 or retinol levels or in hepatic or adipose retinoid (retino

204 oup differences were found for vitamin B-12, retinol, linoleic acid (LA), alpha-linolenic acid (ALA),

205 pated (12.1% deficient on the basis of serum retinol <0.7 mumol/L).

206 VAD (retinol <1.05 mumol/L) was present in 10% of this predom

207 ignificant inverse association between serum retinol, lycopene, and RBP4 concentrations with fibrosis

208 -retinol and hip fracture and whether high s-retinol may counteract a preventive effect of vitamin D.

209 ay, which suggests the possibility that EtOH-retinol metabolic competition is one of the molecular me

210 ously associated with psoriasis risk such as retinol metabolism (Pcombined = 1.84 x 10(-4)), the tran

211 Several genes involved in retinol metabolism and ECM receptor interaction enable d

212 etabolism and downregulation of genes in the retinol metabolism in wild-type females compared with ER

213 ered activity of metabolic pathways, such as retinol metabolism, occurs downstream of ERalpha activat

214 One such factor is retinol metabolism, which enables cellular uptake of ret

215 ol transport, is supported by LRAT-catalyzed retinol metabolism.

216 of fatty acids (n = 439) and carotenoids and retinol (n = 1,293) using the 3 methods for exclusions.

217 evidence of an adverse effect of high serum retinol on hip fracture or any interaction between retin

218 concentrations of 25-hydroxyvitamin D and s-retinol on hip fracture was observed (P = 0.68).

219 nd prealbumin (22%), the effect of increased retinol on individuals with hypertension was mainly attr

220 receptor STRA6, mediating cellular uptake of retinol, on skin structure and function.

221 es of this protein bound to either all-trans-retinol or retinylamine, the latter a therapeutic retino

222 have suggested that circulating carotenoids, retinol, or tocopherols may be associated with prostate

223 t in red and green rods, suggesting that cis retinol oxidation restricts access to the retina visual

224 Primary I148M HSCs showed reduced retinol (P < 0.001) but higher lipid droplet content (P

225 Retinol plays a vital role in the immune response to inf

226 Vitamin A (all-trans retinol) plays critical roles in mammalian development a

227 ldren had serum retinyl esters >10% of total retinol plus retinyl esters, 16% of children had >5% as

228 Exogenous 9-cis retinol produced robust sensitivity recovery in bleached

229 We find that both ascorbate and RA or retinol promote the derivation of induced pluripotent st

230 indicating that the reduction of retinal to retinol promotes faster clearance of the photoisomerized

231 An attribute of the method is the use of retinol propionate, alpha-tocopheryl propionate and all-

232 ess 11-cis-retinal is converted to all-trans-retinol provides a rationale for the unusually high cont

233 In 1219 blood samples, serum retinol, RBP4, and prealbumin were measured.

234 The retinol-RBP4 complex (holo-RBP) can be recognized by a c

235 zyme responsible for the oxidation of 11-cis-retinol remains unknown.

236 The rate constant for retinol removal increased linearly with IRBP concentrati

237 ments was equivalent to 22, 220, and 175 mug retinol, respectively.

238 Intervention with 11-cis-retinol restored the regeneration of 11-REs in the prese

239 ol levels or in hepatic or adipose retinoid (retinol, retinyl ester, and all-trans-retinoic acid) lev

240 retinal, followed by conversion to all-trans retinol (ROL) for removal from the photoreceptor.

241 bout the impact of obesity on vitamin A (VA)[retinol (ROL)], a nutrient that regulates expression of

242 at high intakes and serum concentrations of retinol (s-retinol) have been observed in epidemiologic

243 Here we show that the oxidoreductase retinol saturase (RetSat) is involved in the development

244 Here Heidenreich et al. show that retinol saturase is implicated in hepatic lipid metaboli

245 Analysis of the products of deuterated retinol showed a lack of scrambling of a putative allyli

246 Serum retinol (SR) concentration is a common indicator of vita

247 iation between helminth infections and serum retinol [standardized mean difference (SMD): -0.30; 95%

248 In addition to the assessment of total-body retinol stores (TBSs) by using RID, tests included analy

249 e biomarkers were consistent with high liver retinol stores determined by using retinol isotope dilut

250 Retinol stores in the liver lasted for approximately 2 w

251 esters, which was consistent with high liver retinol stores.

252 We demonstrated in vitro and ex vivo that retinol supplementation enhances ATP synthesis in the pr

253 Vitamin A (VA; retinol) supplementation is used to reduce child mortali

254 results show that the retina produces 11-cis retinol that can be oxidized and used for pigment regene

255 This study explores the nature of the cis retinol that Muller cells in the retina provide to cones

256 c carrier in the bloodstream for hydrophobic retinol, the main form in which vitamin A is transported

257 For retinol, the OR for the highest compared with the lowest

258 parate alpha-retinol derivatives from active retinol.This study aimed to accurately characterize inte

259 sting a possible mode for internalization of retinol through direct diffusion into the lipid bilayer.

260 Oxidation of 11-cis-retinol to 11-cis-retinal is accomplished by a family of

261 P450 27C1 oxidized all-trans-retinol to 3,4-dehydroretinol, 4-hydroxy (OH) retinol, a

262 ammation, serum amyloid A proteins transport retinol to infected tissues.

263 se (LRAT), which catalyzes esterification of retinol to its storage species retinyl esters, is necess

264 10 (RDH10), which catalyzes the oxidation of retinol to retinaldehyde, and two subunits of NADPH-depe

265 Ratios of serum retinol to retinol-binding protein did not deviate from

266 lular uptake of vitamin A by recognizing RBP-retinol to trigger release and internalization of retino

267 uated the associations of plasma carotenoid, retinol, tocopherol, and vitamin C concentrations and ri

268 evel and action are associated with impaired retinol transport and storage in adipose tissue in Lcn2

269 onse to infection, yet proteins that mediate retinol transport during infection have not been identif

270 reas the receptor mediating RBP4 binding and retinol transport into the liver has just recently been

271 Coupled to retinol transport, holo-RBP can activate STRA6-driven Ja

272 RA6 signaling, which requires STRA6-mediated retinol transport, is supported by LRAT-catalyzed retino

273 ue, Skazik et al. demonstrate that the STRA6 retinol transporter protein regulates the proliferation

274 The retinol transporter RBP4 was increased in adipose tissue

275 al, nonhepatic organs is limited.We examined retinol uptake and turnover in nonhepatic organs, includ

276 binding protein receptor 2 (Rbpr2) for RBP4-retinol uptake in developing embryos, using eye developm

277 results demonstrate that Rbpr2-mediated RBP4-retinol uptake in developing liver and intestine is nece

278 cithin:retinol acyltransferase to facilitate retinol uptake in some cell types.

279 The protein levels of STRA6 responsible for retinol uptake were significantly decreased in adipose t

280 pr2 localized to membranes and promoted RBP4-retinol uptake.

281 rans-retinal generated by light to all-trans-retinol using single cell fluorescence imaging.

282 We show that vitamin A (all-trans-retinol) (VA) is required both for the maintenance of pa

283 n which Muller cells recycle spent all-trans-retinol visual chromophore back to 11-cis-retinol.

284 ovitamin A carotenoid, is cleaved to produce retinol (vitamin A) and alpha-retinol (with negligible v

285 Here we report that retinoic acid (RA) or retinol (vitamin A) and ascorbate (vitamin C) act as mod

286 -ALDH pathway also governs the metabolism of retinol (vitamin A) to its transcriptionally active meta

287 y of retinaldehyde is further metabolized to retinol (vitamin A), esterified and packaged into triacy

288 tinoic acid (atRA), an autacoid derived from retinol (vitamin A), regulates energy balance and reduce

289 ls that STRA6 functions as a "gatekeeper" in retinol (vitamin A)-mediated differentiation of human sk

290 y to bind small hydrophobic ligands, such as retinol, vitamins and fatty acids.

291 Neither 3-OH nor 4-OH retinol was an intermediate in desaturation.

292 In all subjects, a majority of alpha-retinol was esterified to palmitic acid (as compared wit

293 When retinol was included in the diet, it accumulated more in

294 ith offspring bone size and growth at birth: retinol was negatively associated with these measurement

295 retinol-binding protein (RBP-ROH), and total retinol were estimated in WinSAAM software.VA supplement

296 e, which may play a role in the retention of retinol when vitamin A is low.

297 Mouse and human SAAs bound retinol with nanomolar affinity, were associated with re

298 ved to produce retinol (vitamin A) and alpha-retinol (with negligible vitamin A activity).

299 sent study will produce sufficient all-trans retinol within the interphotoreceptor matrix to explain

300 tested in vivo if a persistent oversupply of retinol would further impair glucose metabolism in a mou