ライフサイエンスコーパス: retinyl palmitate

1 10]-retinol (formed by hydrolysis of [13C10]-retinyl palmitate).

2 heryl polyethylene glycol-1000 succinate and retinyl palmitate.

3 ximately the same affinity as does all-trans-retinyl palmitate.

4 rots or 2000 microg retinol equivalents/d as retinyl palmitate.

5 ed in vivo in Lrat-/- mice supplemented with retinyl palmitate.

6 min A as liver, amaranth leaves, carrots, or retinyl palmitate.

7 , reduced stress fibers, and accumulation of retinyl palmitate.

8 alpha-carotene, lycopene, phylloquinone, and retinyl palmitate.

9 h levels of retinoic acid (RA), retinol, and retinyl palmitate.

10 D50580 and AY034877 also hydrolyzed retinyl palmitate.

11 icrograms/g diet) or by supplementation with retinyl palmitate.

12 ms of atRA per g of diet in combination with retinyl palmitate.

13 atios were 0.61 (95% CI: 0.23, 1.64; NS) for retinyl palmitate, 0.30 (95% CI: 0.11, 0.85) for beta-ca

14 Some A-rats were repleted wih retinyl palmitate 16 days before being killed and then g

15 stpartum, 7000 mug of retinol equivalents as retinyl palmitate, 42 mg of all-trans beta carotene, or

16 Retinyl palmitate absorption was reduced by 45 and 60% i

17 A- deficient diet (A-) or the same diet with retinyl palmitate added back in a nonrestricted manner (

18 ultaneous quantification of retinyl acetate, retinyl palmitate, alpha-tocopherol and gamma-tocopherol

19 lasma were isolated and extracted, and alpha-retinyl palmitate (alphaRP) and retinyl palmitate were m

20 ation of [8,9,10,11,12,13,14,15,19,20-13C10]-retinyl palmitate and [12,13,14,15,20,12',13',14',15',20

21 the quantification of the bioavailability of retinyl palmitate and beta-carotene and the bioconversio

22 ol to the major storage esters of vitamin A, retinyl palmitate and retinyl stearate, as well as sever

23 ne-5,6-epoxide, all-trans-beta-carotene, and retinyl palmitate and subjected to reverse-phase HPLC fr

24 lthy men ingested a high-fat meal containing retinyl palmitate and were given either GLP-2 or placebo

25 (including tamoxifen, 13-cis-retinoic acid, retinyl palmitate, and an acyclic retinoid) are clinical

26 Amounts of vitamin E, retinyl palmitate, and protein in tissues from rhesus mo

27 Tissues were analyzed for vitamin E, retinyl palmitate, and protein.

28 er with measurement of TRL triglyceride, TRL retinyl palmitate, and TRL apoB-48 levels.

29 (14)C-beta-carotene and (14)C-retinyl palmitate appeared in plasma 0.25 d after the do

30 l-trans-retinol into authentic [3H]all-trans-retinyl palmitate as chemically determined.

31 With retinyl palmitate as substrate, the enzyme had a pH opti

32 beta-carotene, as indicated through reduced retinyl palmitate:beta-carotene ratios in the triglyceri

33 ng for tRP is highly specific because 11-cis-retinyl palmitate binds with a K(D) = 14 nM, 11-cis-reti

34 show that Rpe65 specifically binds all-trans-retinyl palmitate but not 11-cis-retinyl palmitate by a

35 s all-trans-retinyl palmitate but not 11-cis-retinyl palmitate by a spectral-shift assay, by co-eluti

36 Higher retinyl palmitate concentrations were associated with a

37 Plasma lipid and retinyl palmitate concentrations were measured in the fa

38 and sex) of vitamin A (300, 400, or 600 mug retinyl palmitate/d) or vitamin A + zinc (10 or 20 mg zi

39 r 10.5 micromol RE of unlabeled supplemental retinyl palmitate during a 75- or 129-d period.

40 tpartum 1) a single dose of 60 mg retinol as retinyl palmitate followed by daily placebos (n = 69), 2

41 lled trial of supplemental beta-carotene and retinyl palmitate for the chemoprevention of lung cancer

42 , and tocopherols in salad vegetables and 2) retinyl palmitate formed from the provitamin A carotenoi

43 o extract its insoluble substrate, all-trans-retinyl palmitate, from the lipid bilayer for synthesis

44 day 4 with an oral dose of either VA (6 mug retinyl palmitate/g body weight) or canola oil (control)

45 ps were compared with the mean change in the retinyl palmitate group to estimate the relative equival

46 According to the literature, retinyl palmitate has been found to be the most abundant

47 es that are expressed in the liver and their retinyl palmitate hydrolase activity is not known.

48 ter ovary cells overexpressing HSL catalyzed retinyl palmitate hydrolysis in a time-, protein-, and s

49 dipocytes and demonstrated that it catalyzed retinyl palmitate hydrolysis.

50 dentifies PNPLA3 as a lipase responsible for retinyl-palmitate hydrolysis in HSCs in humans.

51 Using retinyl palmitate in a micellar assay system the enzyme

52 -null mice have normal levels of retinol and retinyl palmitate in liver, serum, and adipose tissue, b

53 e isoenzymes will regulate the metabolism of retinyl palmitate in specific rat cells and tissues.

54 Mean (+/- SD) areas under the curve for retinyl palmitate in the TRL fractions (nmol h) were 24.

55 ow that purified wild-type PNPLA3 hydrolyzes retinyl palmitate into retinol and palmitic acid.

56 also similar in both strains when all-trans-retinyl palmitate is used as substrate.

57 e retinoic acid reductions, both retinol and retinyl palmitate levels in the livers of the alcohol-fe

58 by alpha-tocopherol, beta-carotene, retinol, retinyl palmitate, N-acetylcysteine, or isotretinoin in

59 te-dependent manner, with an apparent Km for retinyl palmitate of 161 microM, whereas homogenates fro

60 rmal birthweight neonates to NVAS (50 000 IU retinyl palmitate) or placebo together with their Bacill

61 crog RE/d as sweet potatoes, Indian spinach, retinyl palmitate, or beta-carotene (RE = 1 microg retin

62 rified NREH shows a substrate preference for retinyl palmitate over triolein and did not catalyze the

63 r Indian spinach (P = 0.033), 0.065 mmol for retinyl palmitate (P < 0.001), and 0.062 mmol for beta-c

64 levels of TRL triglycerides (P = .007), TRL retinyl palmitate (P = .002), and TRL apoB-48 (P = .04)

65 000 IU of retinol (vitamin A) in the form of retinyl palmitate per day on the primary end point, the

66 ented with a source of retinol (100 units of retinyl palmitate per day).

67 ), triacylglycerol (r = 0.77, P < 0.05), and retinyl palmitate (r = 0.68, P = 0.06) and with the Sf >

68 lglycerol (r = 0.72, P < 0.05), and Sf > 400 retinyl palmitate (r = 0.75, P < 0.01) lipoprotein fract

69 ted with the postprandial triacylglycerol or retinyl palmitate response.

70 Retinyl palmitate (RP) was the only vitamin that could b

71 a (BPD) than single measurements of retinol, retinyl palmitate (RP), or retinol binding protein (RBP)

72 ing killed and then given free access to the retinyl palmitate-supplemented diet (R).

73 significantly less retinyl ester, especially retinyl palmitate, than milk obtained from wild type dam

74 ulates the enzymatic conversion of all-trans-retinyl palmitate to 11-cis-retinol in microsomes from b

75 we show that purified RPE65 binds all-trans-retinyl palmitate (tRP) with a K(D) = 20 pM.

76 doses of 7000 microg retinol equivalents as retinyl palmitate (vitamin A), 42 mg all-trans-beta-caro

77 k either 850 microg retinol equivalents/d as retinyl palmitate, vitamin A-fortified rice, goat liver,

78 Retinyl palmitate was analyzed in plasma triacylglycerol

79 Tissue retinyl palmitate was inversely and significantly correl

80 standard and fluorescence detection, whereas retinyl palmitate was quantified with an external standa

81 weeks of daily oral vitamin A (10,000 IU of retinyl palmitate) was conducted among 400 HIV-1-infecte

82 the noon meal, the ensuing concentrations of retinyl palmitate were also higher after ingestion of th

83 d, and alpha-retinyl palmitate (alphaRP) and retinyl palmitate were measured over 12 h postprandially

84 There was a weak downward trend of tissue retinyl palmitate with increasing fibrosis stage.

85 Michaelis-Menten kinetics for hydrolysis of retinyl palmitate with Km values of about 1 micro m and

86 Incubation of all-trans [(3)H]-retinyl palmitate with RPE microsomes generated 11-cis r