ライフサイエンスコーパス: retroposition

1 e in a process mediated by retrotransposons (retroposition).

2 d genes suggest that most were generated via retroposition.

3 e and scored a set of features indicative of retroposition.

4 iases of the retroelement machinery used for retroposition.

5 dentified pattern of the between-chromosomal retroposition.

6 ly understood RNA-mediated mechanism, termed retroposition.

7 Four of these five have arisen by retroposition.

8 ments are dispersed through a process termed retroposition.

9 ght monomer is a critical determinant of Alu retroposition.

10 via an RNA intermediate in a process termed retroposition.

11 opose that the primate-specific burst of Alu retroposition activity (which occurred 35-40 million yea

12 l" length, a feature correlated with current retroposition activity, varied between Alu Sx element lo

13 splicing-based model in conjunction with the retroposition and Fink models can explain the IR-type ge

14 DNA elements, undergo amplification through retroposition and subsequent integration into a new loca

15 We further discovered that retropositions are associated with greater evolutionary

16 cept of exon shuffling from recombination to retroposition as a general molecular mechanism for the o

17 wo or more parental genes, demonstrating LTR-retroposition as a novel mechanism of exon shuffling.

18 In mammals, L1 retrotransposons drive retroposition, but the elements responsible for retropos

19 scription would directly affect an element's retroposition capability.

20 retropose, and the factors determining their retroposition capacity are poorly understood.

21 identify Alu elements that were potentially retroposition competent.

22 Mining the databases for putative retroposition-competent elements that share 100% nucleot

23 Retroposition contributed to the gene content of the hum

24 , we hypothesize that a mechanism resembling retroposition controls 5S rRNA gene amplification, dispe

25 to L1 long interspersed transposable element retroposition during mammalian evolution but universally

26 romosomal-level comparison examining the Alu retroposition dynamics following the divergence of human

27 interspersed DNA elements (SINEs) amplify by retroposition either by (i) successive waves of amplific

28 s appear to have resulted from more than one retroposition event.

29 Similarly, autosome-to-X retroposition events are associated with lower maximal e

30 These mRNA retroposition events fall into three categories: I) 34 r

31 and REX1, although generated through similar retroposition events have undergone different selection

32 force for the evolutionary fixation of these retroposition events was postulated to be the stochastic

33 in retrogenes using a total of 94 Drosophila retroposition events we recently identified.

34 ighly diverse, intronless opsins expanded by retroposition for broadened spectral sensitivity.

35 tion indicated that Ifc-2h resulted from the retroposition from its parental gene, Infertile crescent

36 r, there is an excess of genes duplicated by retroposition from the X chromosome to the autosomes.

37 Alu RNA stability, scAlu RNA production, and retroposition has been unknown.

38 The analyses of gene duplications by retroposition have revealed an excess of male-biased dup

39 Drosophila and mammals of inter-chromosomal retroposition have revealed that during evolution the re

40 mplicates a role of the mutation process for retroposition in determining chromosomal locations of au

41 t our genomic analysis of within-chromosomal retroposition in Drosophila melanogaster, and compare it

42 he pattern of origin of the genes created by retroposition in Drosophila.

43 roposition, but the elements responsible for retroposition in other animals have yet to be identified

44 They also indicate a role of genomic retroposition in the phylogenetic development of RNA tar

45 studies suggested an elevated rate of recent retroposition in the rhesus macaque genome.

46 to its subsequent reverse transcription and retroposition into the genome.

47 Altogether, our data support that retroposition is an important force to shape genome evol

48 Retroposition is an RNA-mediated mechanism to generate g

49 This retroposition is estimated to have occurred after the di

50 Overall, our data show that LTR-mediated retroposition is highly conserved across a wide range of

51 f the first F-lectin repeat, suggesting that retroposition is one mechanism by which F-lectin repeats

52 Retroposition is responsible for generating one duplicat

53 pseudogene that has arisen by duplication or retroposition may, at first, not be subject to natural s

54 quence features indicative of the underlying retroposition mechanism.

55 d gene conversion, dubbed the Fink model and retroposition model.

56 CDY genes arose during primate evolution by retroposition of a CDYL mRNA and amplification of the re

57 s role in male fecundity, originated through retroposition of a highly conserved housekeeping gene, C

58 ed pseudogene originating from a very recent retroposition of a PGAM 1 transcript.

59 TAF1L lacks introns and evidently arose by retroposition of a processed TAF(II)250 mRNA during prim

60 line expression is crucial for the heritable retroposition of cellular mRNAs, little is known about t

61 hypothesis that natural selection favors the retroposition of genes out of the X chromosome.

62 d compartmentalization of translation on the retroposition of processed pseudogenes.

63 segments in eukaryotic genomes involved the retroposition of repetitive DNA elements in conjunction

64 an X-linked homeobox gene that originated by retroposition of the autosomal gene TGIF2, most likely i

65 PGAM 1 cDNA and probably represents a recent retroposition of this parent PGAM 1 mRNA.

66 hesis is the finding of a similar X-autosome retroposition of UTP14 in human which seems to have aris

67 t K81 arose through duplication, most likely retroposition, of a ubiquitously expressed gene before t

68 To better understand the impact of retroposition on macaque species which have undergone an

69 y duplicated genes lack signatures of either retroposition or DNA-based mechanisms, but other feature

70 Hence, retroposition plays a role in plant genome evolution, an

71 belong to the Yc1 subfamily, supporting the retroposition potential of this subfamily and demonstrat

72 The retroposition process involves a number of potential reg

73 d elements are inserted into the genome by a retroposition process that occurs via dimeric Alu RNA an

74 rt-chain alcohol dehydrogenase (ADH) through retroposition, provides an opportunity to examine this p

75 account for the observed fluctuation in Alu retroposition rates across primate taxa.

76 To protect against L1 retroposition, the cell downregulates the expression of

77 correlate highly with the rate of inherited retroposition: the source of processed pseudogenes in th