ライフサイエンスコーパス: reverse gyrase

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1 followed by their sequential annealing with reverse gyrase.

2 hemical properties of Archaeoglobus fulgidus reverse gyrase.

3 cases, but until now were shown for no other reverse gyrase.

4 mechanism of positive supercoil induction by reverse gyrase.

5 1% identity), and the Methanopynrus kandleri reverse gyrase (37% identity).

6 all identity), the Sulfolobus acidocaldarius reverse gyrase (41% identity), and the Methanopynrus kan

7 he sequences of the Methanococcus jannaschii reverse gyrase (48% overall identity), the Sulfolobus ac

8 This dramatic enhancement of the reverse gyrase activity is also correlated with the appe

9 Reverse gyrase also displays exquisite sensitivity towar

10 trand passage of two type IA topoisomerases: reverse gyrase and a protein complex of topoisomerase II

11 Reverse gyrases are ATP-dependent type I 5'-topoisomeras

12 Reverse gyrase can completely relax positively supercoil

13 We report here several activities that reverse gyrase can efficiently mediate with a substoichi

14 coiling of bubble substrate demonstrate that reverse gyrase can function as a DNA renaturase.

15 ese biochemical activities also suggest that reverse gyrase can have an important biological function

16 A substoichiometric amount of reverse gyrase can insert positive supercoils into DNA w

17 In the presence of a nucleotide cofactor, reverse gyrase can readily relax negative supercoils, bu

18 Reverse gyrase comprises an N-terminal ATPase and a C-te

19 o close over the topoisomerase domain in the reverse gyrase crystal structure.

20 rgeted protection mechanism in vivo in which reverse gyrase detects damaged DNA and acts as a molecul

21 Reverse gyrase efficiently anneals complementary single-

22 ydrolysis is essential to the specificity of reverse gyrase for increasing the linking number of DNA.

23 We have determined the crystal structure of reverse gyrase from Archaeoglobus fulgidus in the presen

24 Reverse gyrase from Methanopyrus kandleri is unique as t

25 nctional characterization of PcalRG, a novel reverse gyrase from the archaeon Pyrobaculum calidifonti

26 A recently described reverse gyrase from the hyperthermophilic methanogen Met

27 Here we report the reconstitution of active reverse gyrase from the two recombinant proteins overexp

28 The reverse gyrase gene rgy from the hyperthermophilic archa

29 Reverse gyrase has a minor nonspecific effect on the rat

30 Purified P. furiosus reverse gyrase has a sedimentation coefficient of 6S, su

31 Reverse gyrase is a DNA topoisomerase specific for hyper

32 Reverse gyrase is a hyperthermophile-specific enzyme tha

33 The P. furiosus reverse gyrase is a monomeric protein, containing a heli

34 Reverse gyrase is a unique type IA topoisomerase that ca

35 Reverse gyrase is able to anneal single strands, thereby

36 This suggests that the mechanism of reverse gyrase is best described by a combination of rec

37 Reverse gyrase is the only topoisomerase known to positi

38 PcalRG is the most robust and processive reverse gyrase known to date; it is active over a wide r

39 en the topoisomerase and helicase modules of reverse gyrase occurred before the divergence of the two

40 that assist unfolded proteins, we found that reverse gyrase prevents inappropriate aggregation of den

41 Reverse gyrase reanneals denatured DNA and induces posit

42 Using electron microscopy, we show that reverse gyrase recognizes nicked DNA and recruits a prot

43 ated that efficient positive supercoiling by reverse gyrase requires a bubble size larger than 20 nuc

44 ur results suggest for the first time that a reverse gyrase shares not only structural but also funct

45 We show that reverse gyrase, the only protein that is both specific a

46 Reverse gyrase, the only topoisomerase known to positive

47 ylogenetic analysis indicates that all known reverse gyrase topoisomerase modules form a subgroup ins

48 ilarity with the thermophile-specific enzyme reverse gyrase, which catalyzes positive supercoiling of

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