ライフサイエンスコーパス: ribonuclease

1 ion can regulate the activity of a bacterial ribonuclease.

2 tranded RNA substrates, a rare quality among ribonucleases.

3 because its minimal genome encodes very few ribonucleases.

4 due to its susceptibility to degradation by ribonucleases.

5 ript to attack by 5'-monophosphate-dependent ribonucleases.

6 ertoire of regulatory strategies employed by ribonucleases.

7 transcripts had little in common between the ribonucleases.

8 monophosphate-assisted cleavage by these two ribonucleases.

9 rovide evidences that the Arabidopsis S-like Ribonuclease 1 (RNS1) might be involved in the biogenesi

10 use of the Csy-type (CRISPR system yersinia) ribonuclease 4 (Csy4) and tRNA processing enzymes to sim

11 Angiogenin (ANG) and ribonuclease 4 (RNASE4), two members of the secreted and

12 Using ribonuclease A (RNase A) and saporin as two representati

13 miting millisecond motions in wild-type (WT) Ribonuclease A (RNase A) are modulated by histidine 48.

14 ffusivity of the positively charged protein, ribonuclease A (RNase), in solutions of dextrans of vari

15 kinetics, as demonstrated by the binding of ribonuclease A (RNaseA, 13.7 kDa) with cytidine nucleoti

16 panning the N-terminal 20 residues of bovine ribonuclease A (S peptide).

17 models of ribonuclease cleavage and for the ribonuclease A enzyme itself, based on our studies of th

18 atalysis of RNA 2'-O-transphosphorylation by ribonuclease A is proposed to involve electrostatic stab

19 eight cysteine residues of reduced unfolded ribonuclease A or to site-specific locations using appro

20 tations in Angiogenin (ANG), a member of the Ribonuclease A superfamily (also known as RNase 5) are k

21 tations in angiogenin (ANG), a member of the ribonuclease A superfamily, are associated with amyotrop

22 n-6 with barium chloride, and the binding of ribonuclease A with cytidine 2'-monophosphate within rea

23 For nontarget components of the mixture (ribonuclease A, holotransferrin, and apomyoglobin), the

24 pon unfolding of model proteins lysozyme and ribonuclease A, in solutions containing varying cosolute

25 helix formation in the isolated C-peptide in ribonuclease A, there is growing evidence that a signifi

26 Model proteins were studied: ribonuclease A, trypsin inhibitor, and carbonic anhydras

27 reduced non-specific displacement by BSA and ribonuclease A.

28 process analogous to that used by the enzyme ribonuclease A.

29 nthesis that involves the ECERIFERUM7 (CER7) ribonuclease, a core subunit of the exosome.

30 The retention of a conserved ribonuclease active site as well as traits normally asso

31 'lasso' because it binds RNA and stimulates ribonuclease activities associated with Rrp44 and Rrp6 w

32 Cas13a (formerly C2c2) contains two separate ribonuclease activities that catalyze crRNA maturation a

33 ier studies have identified the regulator of ribonuclease activity A (RraA) as a potential interactio

34 data highlight a communicative link between ribonuclease activity and central metabolism that may ha

35 We show that the Xbp1-specific ribonuclease activity depends on autophosphorylation, an

36 ome is a well-conserved protein complex with ribonuclease activity implicated in RNA metabolism.

37 combinant RNase 7 mutant showed that RNase 7 ribonuclease activity is dispensable for the observed re

38 The ribonuclease activity of deadenylase enzymes is attribut

39 ntly to animal cells, it does not temper the ribonuclease activity of inositol-requiring enzyme 1 (IR

40 forms of IRE1b it was demonstrated that the ribonuclease activity of IRE1 was required for protectin

41 Here we detail methods for detection of the ribonuclease activity of MazFSa, including a continuous

42 Loss of BMI1 enhanced ribonuclease activity of polynucleotide phosphorylase an

43 Ribonuclease activity of topoisomerase I (Top1) causes D

44 The toxin exerts a unique ribonuclease activity that cleaves the single-stranded 3

45 tly exhibited heightened levels of cytosolic ribonuclease activity that corresponded to substantial d

46 xhibits a "collateral effect" of promiscuous ribonuclease activity upon target recognition.

47 elicase activity and its relationship to the ribonuclease activity were not clear.

48 toxin 28 (Ntox28) domain that only exhibits ribonuclease activity when bound to the cysteine biosynt

49 vented S-nitrosylation and inhibition of its ribonuclease activity, indicating that Cys931 is the pre

50 e S-nitrosylation of IRE1alpha inhibited its ribonuclease activity, S-nitrosylation of PERK activated

51 sure to heat, leaving Sll1130 to exhibit its ribonuclease activity.

52 helicase activity that is independent of its ribonuclease activity.

53 spondence between its in vitro activity as a ribonuclease and control of bacteriostasis in vivo.

54 y of siRNA inside even after incubation with ribonuclease and serum for 1 h; under the same condition

55 We demonstrated that Zt6 is a functional ribonuclease and that phytotoxicity is dependent on both

56 nner, but only the l system is impervious to ribonucleases and can operate, for example, in the prese

57 of this family maintain independent roles as ribonucleases and modulators of innate immunity.

58 Specialized ribonucleases and RNA-binding proteins govern the produc

59 Nucleus-encoded ribonucleases and RNA-binding proteins influence chlorop

60 terize another RNase 1 homolog, bovine brain ribonuclease, and find pronounced similarities between t

61 iginal method that involves a combination of ribonuclease- and detergent-based preextraction with hig

62 The ribonuclease angiogenin is a component of the mammalian

63 The ribonuclease angiogenin is a component of the mammalian

64 mature tRNAs are cleaved by stress-activated ribonuclease angiogenin to generate 5'- and 3'-tRNA halv

65 around the anticodon loop via the use of the ribonuclease angiogenin.

66 related with expression of the tRNA-cleaving ribonuclease, angiogenin.

67 transcription and availability of the Dicer ribonuclease are the key determinants for primary siRNA

68 with each other, and how they interface with ribonucleases are active areas of discovery.

69 in vivo, and that the activities of the two ribonucleases are co-ordinated.

70 T2 ribonucleases are conserved nucleases that affect a vari

71 Ribonucleases are critically important in many cellular

72 rd proteins myoglobin (m/z-value 16,950) and ribonuclease B (m/z-value 14,900) were measured with res

73 sylation (kappa casein) and N-glycosylation (ribonuclease B).

74 oteins alpha1-acid glycoprotein, fetuin, and ribonuclease B, as well as from glycoproteins collected

75 The model glycoproteins included ribonuclease B, fetuin, alpha(1)-acid glycoprotein, immu

76 the well-characterized glycoproteins bovine ribonuclease B, human transferrin, bovine fetuin and hum

77 ed beta-casein, calmodulin, and glycosylated ribonuclease B.

78 of noncovalently bound holo-myoglobin and of ribonuclease B.

79 and were fully active as the natural bovine ribonuclease B.

80 r was replaced with a gene encoding a lethal ribonuclease, barnase, demonstrating that the INPACT sys

81 th mRNAs, (e) regulatory proteins that alter ribonuclease binding affinities, (f) the presence or abs

82 ous ribonucleases or induction of endogenous ribonucleases by trypsin reagent proteases to RNA degrad

83 the programmable single-effector RNA-guided ribonuclease Cas13.

84 in the PARN gene (encoding poly(A)-specific ribonuclease) cause telomere diseases including familial

85 s a mechanism we have proposed for models of ribonuclease cleavage and for the ribonuclease A enzyme

86 m contrasts with earlier, generally accepted ribonuclease cleavage mechanisms where the proton donor

87 ar) 11, a divergent member of the eosinophil ribonuclease cluster, and the only known RNase A ribonuc

88 The exosome is a conserved multi-subunit ribonuclease complex that functions in 3' end processing

89 the Pb(2+)-dependent DNAzyme sequence and a ribonuclease-containing nucleic acid sequence (correspon

90 ding proteins HuR and PARN [Poly(A) specific ribonuclease deadenylase].

91 Here we show using RNA-seq analyses of ribonuclease-deficient strains in vivo and a 5'-sensor m

92 hat at the onset of wax production, the CER7 ribonuclease degrades an mRNA specifying a repressor of

93 The human ribonuclease Dicer and its double-stranded RNA (dsRNA)-b

94 The conserved ribonuclease Dicer generates microRNAs and short-interfe

95 triggers RNA-dependent RNA polymerase 6- and ribonuclease Dicer-like 4-dependent biogenesis of 21-nt

96 RNA sequences by mass spectrometry involves ribonuclease digestion followed by LC-MS/MS analysis and

97 , creating a better substrate for subsequent ribonuclease digestion.

98 ain, leading to activation of the C-terminal ribonuclease domain, which splices Xbp1 mRNA generating

99 rizes to activate its cytoplasmic kinase and ribonuclease domains.

100 y the processing of longer precursors by the ribonucleases Drosha and Dicer.

101 In the presence of H-type ribonucleases, DSB repair proceeds through a complementa

102 embled around the unstructured C-terminus of ribonuclease E, a protein not present in B. subtilis.

103 T(H)2-related genes as eosinophil-associated ribonucleases, eosinophil/basophil chemokines, and M2 ge

104 nuclease cluster, and the only known RNase A ribonuclease expressed specifically in response to Th2 c

105 The poly(A)-specific ribonuclease family deadenylase PNLDC1 is implicated in

106 two structural homologues of the pancreatic ribonuclease family: RNase A and eosinophil cationic pro

107 plex without catalytic turnover for EMSA and ribonuclease footprinting analyses.

108 icutes have a fundamentally different set of ribonucleases for mRNA degradation and whether sRNAs can

109 eractions involve coordination with cellular ribonucleases, for example to direct non-canonical proce

110 emonstrate that Drosha and related RNase III ribonucleases from all three domains of life also elicit

111 effector C2c2 and demonstrate its RNA-guided ribonuclease function.

112 These ribonucleases function with the assistance of ancillary

113 nsing, nucleotide binding, dimerization, and ribonuclease functions highlights the evolutionary adapt

114 RNA digestions catalyzed by many ribonucleases generate RNA fragments that contain a 2',3

115 Since the ribonuclease H (RH) domain contains an occult cleavage s

116 rse transcriptase (RT) contains a C-terminal ribonuclease H (RH) domain on its p66 subunit that can b

117 e nucleic acid duplex in the vicinity of the ribonuclease H (RNase H) active site.

118 7447, was proposed to allosterically inhibit ribonuclease H (RNase H) activity of human immunodeficie

119 se (IN) and reverse transcriptase-associated ribonuclease H (RNase H) are both selective targets for

120 zing RTs prevents polymerization-independent ribonuclease H (RNase H) cleavages of the donor template

121 DNTP) occupies the interface between the p66 ribonuclease H (RNase H) domain and p51 thumb of human i

122 ng trajectories of ancestral proteins of the ribonuclease H (RNase H) family using ancestral sequence

123 idated reverse transcriptase (RT) associated ribonuclease H (RNase H) for human immunodeficiency viru

124 (HIV) reverse transcriptase (RT) associated ribonuclease H (RNase H) remains an unvalidated antivira

125 Reverse transcriptase (RT) associated ribonuclease H (RNase H) remains the only virally encode

126 (HIV) reverse transcriptase (RT)-associated ribonuclease H (RNase H) remains the only virally encode

127 INSTIs) that also displayed activity against ribonuclease H (RNase H).

128 associated DNA polymerase, and RT-associated ribonuclease H (RNase H).

129 mains and the acquisition of an Archaea-like ribonuclease H (RNH) domain.

130 all reduction in activity of T. thermophilus ribonuclease H compared to its mesophilic E. coli homolo

131 folding, dimerization and subunit-selective ribonuclease H domain (RH) proteolysis.

132 wn how often mutations in the connection and ribonuclease H domains of reverse transcriptase (RT) eme

133 TEFM contains two HhH motifs and a Ribonuclease H fold, similar to the nuclear transcriptio

134 y essential aspartate to Mg(2+) or Ca(2+) in ribonuclease H from two organisms were computed using um

135 Mutation analyses and analogies to ribonuclease H indicate that insertion of this glutamate

136 These RNA.DNA hybrids are eliminated by ribonuclease H treatment.

137 The kinetic folding of ribonuclease H was studied by hydrogen exchange (HX) pul

138 ne the folding landscape of Escherichia coli ribonuclease H, a protein well characterized by hydrogen

139 the native cofactor in many enzymes such as ribonuclease H, its competitor Ca(2+) may also bind to t

140 Loss-of-function mutations in ribonuclease H, senataxin, and topoisomerase I that reso

141 Ribonuclease H-like (RNHL) superfamily, also called the

142 ribonucleic acid (RNA) backbone catalyzed by ribonuclease H.

143 Ribonucleases H (RNases H) are endonucleases which cleav

144 Encoding ribonuclease H1 (RNase H1) degrades RNA hybridized to DN

145 RNASEH1, encoding ribonuclease H1 (RNase H1), is an endonuclease that is p

146 w the diverse thermostabilities of bacterial ribonuclease H1 (RNH) proteins evolved.

147 NA fiber analysis, we demonstrate that human ribonuclease H1 (RNH1) plays an important role in replic

148 Ribonuclease H1 ameliorates replication fork instability

149 These findings implicate ribonuclease H1 and RNA in the physical segregation of m

150 In cells with a pathological variant of ribonuclease H1 associated with mitochondrial disease, R

151 Ribonuclease H1 is essential for mitochondrial DNA repli

152 at can be disfavored in vitro and in vivo by ribonuclease H1 overexpression, resulting in VIM down-re

153 und that RNA-DNA recombination is blocked by ribonucleases H1 and H2.

154 enes encoding the genome surveillance enzyme ribonuclease H2 (RNase H2) cause Aicardi-Goutieres syndr

155 lleles of the genes encoding subunits of the ribonuclease H2 (RNase H2) complex, known for its role i

156 Ribonuclease H2 (RNase H2) is a nucleic acid repair enzy

157 Ribonuclease H2 (RNase H2) protects genome integrity by

158 Ribonuclease H2 is the major nuclear enzyme degrading ce

159 Ribonuclease H2 plays an essential role for genome stabi

160 In particular, ribonuclease HI (RNase H), an 18 kD globular protein tha

161 ups, (13)C(gamma/delta), in Escherichia coli ribonuclease HI (RNase H).

162 tion formed between Escherichia coli SSB and ribonuclease HI (RNase HI), an enzyme that hydrolyzes RN

163 sis for reduced activity of the thermophilic ribonuclease HI enzyme from Thermus thermophilus, compar

164 One such protein family, the ribonuclease III (RNase III) endonucleases, includes Rnt

165 Ribonuclease III (RNase III) enzymes are a family of dou

166 The Dicer ribonuclease III (RNase III) enzymes process long double

167 Ribonuclease III (RNase III) is a conserved, gene-regula

168 The action of ribonuclease III and the binding of an inactive, dsRNA-b

169 er, a caspase-sensitive, fertility-promoting ribonuclease III enzyme, and key micro-RNAs in the repro

170 existence of citrate-mediated inhibition of ribonucleases in all three domains of life.

171 known about the mechanism of action of other ribonucleases in this microorganism.

172 f trypsin reagent identified the presence of ribonucleases in trypsin derived from animal pancreas.

173 protect siRNAs from degradation by serum and ribonucleases in vitro and upon intratumoral injection i

174 Ribonuclease inactivating point mutations are found in a

175 Experiments with a ribonuclease-inactive recombinant RNase 7 mutant showed

176 kin-derived native RNase 7 and a recombinant ribonuclease-inactive RNase 7 mutant.

177 ome profiling in yeast and mice with various ribonucleases including I, A, S7 and T1, characterized t

178 esigned leucine-rich repeats (LRRs) from the ribonuclease inhibitor (RI) family that assemble into st

179 Ribonuclease inhibitor (RI) is a conserved protein of th

180 gel electrophoresis revealed the endogenous ribonuclease inhibitor as the primary cellular target.

181 entering cells, ANG encounters the cytosolic ribonuclease inhibitor protein, which binds with femtomo

182 collagen I hydrogel membrane with entrapped ribonuclease inhibitors (RI) to protect small molecule R

183 IRE1 is a dual protein kinase/ribonuclease involved in the splicing of bZIP60 mRNA, an

184 cMazF) is the archetype of a large family of ribonucleases involved in bacterial stress response.

185 The plant UPR transducers are the kinase and ribonuclease IRE1 and the transcription factors bZIP28 a

186 volving the bifunctional protein kinase (PK)/ribonuclease, IRE1, a RNA splicing enzyme, and another i

187 Angiogenin (ANG), a secreted vertebrate ribonuclease, is known to promote cell proliferation, le

188 NA, mediated by HuR, KSRP and its associated ribonucleases, is required for proper myogenesis.

189 cking the 5'-->3' exonucleolytic activity of ribonuclease J (RNase J).

190 Here we found that ribonuclease kappa (RNASEK) is essential for the infecti

191 tethered transcription factor bZIP28 and the ribonuclease-kinase IRE1 along with its splicing target,

192 Ribonuclease L (RNase L) is a metal-ion-independent endo

193 Ribonuclease L (RNase L) is activated during viral infec

194 cleavage sites, (g) control of intracellular ribonuclease levels, and (h) physical location within th

195 Here, we use our ribonuclease-mediated structure and RBP-binding site map

196 re intrinsically resistant to degradation by ribonucleases, might be pursued as an alternative to ant

197 nces flanking A3 and to the RNA component of ribonuclease MRP, which cleaves site A3.

198 Our results suggest that brain ribonuclease, not RNase A, is the true bovine homolog of

199 MBL domain with CPSF73, as well as to other ribonucleases of the MBL superfamily.

200 ncentration or specific activity of cellular ribonucleases or by unmasking the mRNA-degrading activit

201 The contribution of exogenous ribonucleases or induction of endogenous ribonucleases b

202 with MRPP2 and MRPP3, form the mitochondrial ribonuclease P (mt-RNase P) complex that cleaves the 5'

203 The mitochondrial form of ribonuclease P (mt:RNase P) is responsible for 5'-end ma

204 Ribonuclease P (RNase P) and RNase MRP are closely relat

205 Ribonuclease P (RNase P) catalyzes the maturation of the

206 Ribonuclease P (RNase P) is a ribonucleoprotein complex

207 Ribonuclease P (RNase P) is an endonuclease that catalyz

208 Ribonuclease P (RNase P) is an essential endonuclease th

209 Ribonuclease P (RNase P) is one of the first ribozymes d

210 re like a pre-tRNA and recruit intracellular ribonuclease P (RNase P), a tRNA processing enzyme, to d

211 0 is an essential component of mitochondrial Ribonuclease P (RNase P), an enzyme required for mitocho

212 A single enzyme, ribonuclease P (RNase P), processes the 5' ends of tRNA

213 probe functions of conserved nucleobases in ribonuclease P (RNase P).

214 ocessing of precursor transfer RNA (tRNA) by ribonuclease P as a model system.

215 Ribonuclease P complexed with external guide sequence (E

216 dize with any mRNA and recruit intracellular ribonuclease P for specific degradation of the target mR

217 mponents-such as the RNA moiety of bacterial ribonuclease P-can sometimes be replaced with a highly d

218 uR with the decay factor KSRP as well as the ribonuclease PARN and the exosome.

219 However, the role of poly(A) specific ribonuclease (PARN) deadenylase in miRNA-dependent mRNA

220 ations in the gene encoding poly(A)-specific ribonuclease (PARN) in 3 families with individuals exhib

221 ns in the gene encoding the poly(A)-specific ribonuclease (PARN) in individuals with a severe form of

222 Poly(A)-specific ribonuclease (PARN) is required for posttranscriptional

223 Here, we show that poly(A)-specific ribonuclease (PARN) participates in steps leading to 18S

224 coding mutations in TERT or poly(A)-specific ribonuclease (PARN), another gene linked to telomerase f

225 ck loop between p53 and the poly(A)-specific ribonuclease (PARN), in which PARN deadenylase keeps p53

226 Ribonucleases play an important role in RNA metabolism.

227 Ribonucleases play essential roles in all aspects of RNA

228 biochemical function in the pancreatic-type ribonuclease (ptRNase) superfamily.

229 Ribonuclease R (RNR1) and polynucleotide phosphorylase (

230 vity, which bares resemblance to that of the ribonuclease reductase responsible for cellular dNTP pro

231 ort the hypothesis that RNase J is the major ribonuclease responsible for maturing chloroplast mRNA 5

232 cts RNA from degradation when isolating from ribonuclease-rich matrices (such as blood), and produces

233 assembly, and its interaction with the core ribonuclease RNase E boosts the ATP-dependent activity o

234 e regulatory small RNA GlmZ to the essential ribonuclease RNase E for inactivation.

235 d processing of many RNAs is mediated by the ribonuclease RNase J, a member of the widely occurring m

236 Previously, endonucleolytic cleavage by ribonuclease RNase J1 in a 3'-proximal, single-stranded

237 ting evidence suggests that human pancreatic ribonuclease (RNase 1) plays important roles in vivo, ra

238 e mitochondria, the nucleus harbors a second ribonuclease (RNase H2).

239 ng the relative concentrations of the native ribonuclease (RNase) A protein and RNase B glycoprotein

240 ing several model protein systems including: ribonuclease (Rnase) A, myoglobin, bovine carbonic anhyd

241 of the monoglucosylated glycoforms of bovine ribonuclease (RNase) as specific ligands of lectin-like

242 ntly enhance the number of detected modified ribonuclease (RNase) digestion products by approximately

243 Compounds that efficiently inhibit the ribonuclease (RNase) H activity of the human immunodefic

244 The ribonuclease (RNase) H class of enzymes degrades the RNA

245 Ribonuclease (RNase) H enzymes that recognize and proces

246 an RNA/DNA hybrid substrate by B. halodurans ribonuclease (RNase) H1 using hybrid quantum-mechanics/m

247 Mutations that impair ribonuclease (RNase) H2 enzyme function are the most fre

248 Human ribonuclease (RNase) H2 is the principal enzyme able to

249 ficiently removed in an error-free manner by ribonuclease (RNase) H2.

250 oligoadenylate (2-5A) synthetases (OASs) and ribonuclease (RNase) L are components of a potent host a

251 Ribonuclease (RNase) MRP is a ubiquitous and essential s

252 The kinase activity of PERK and ribonuclease (RNase) of IRE1alpha mediated the upregulat

253 ore obstacles to delivery which include poor ribonuclease (RNase) resistance, short biological half-l

254 Omega-1, a glycosylated T2 ribonuclease (RNase) secreted by Schistosoma mansoni egg

255 The RNA exosome is an essential multisubunit ribonuclease (RNase) that contributes to cytoplasmic and

256 Angiogenin (ANG) is a secreted ribonuclease (RNase) with cell-type- and context-specifi

257 culum (ER) resident transmembrane kinase and ribonuclease (RNase), in response to ER stress.

258 and glycosylated forms of bovine pancreatic ribonuclease (RNase).

259 related molecules (keratin 25, trichohyalin, ribonuclease, RNase A family, 7) and inflammation-relate

260 Pancreatic ribonuclease (RNASE1) is a digestive enzyme that has bee

261 inds with high affinity to diverse secretory ribonucleases (RNases) and inhibits their enzymatic acti

262 Ribonucleases (RNases) can be crucial factors contributi

263 Ribonucleases (RNases) maintain the cellular RNA pool by

264 IBIND and its human homologue RNASET2 are T2 ribonucleases (RNases).

265 inally, we provide evidence that Arabidopsis ribonuclease RNS1 might be involved in the processing an

266 The method is tested on the model protein ribonuclease S (RNase S) containing a labeled p-CN-Phe n

267 Human calmodulin and bovine ribonuclease S (RNase S) were screened against the libra

268 -averaged electric fields in solvents and in ribonuclease S and found excellent correlation between c

269 in binding peptide and S peptide as the only ribonuclease S binding peptide in the library.

270 bes in different solvent environments and in ribonuclease S to understand the sensitivity of carbonyl

271 oteins previously studied in our laboratory, ribonucleases Sa and T1.

272 This study provides a guide for ribonuclease selection in ribosome profiling experiments

273 e report that human RNase 1 and bovine brain ribonuclease share high catalytic activity against doubl

274 oblot analyses in the presence or absence of ribonuclease showed that these five RBPs are assembled i

275 ar how nascent pre-miRNAs are protected from ribonucleases, such as MCPIP1, that degrade pre-miRNAs t

276 bers of the secreted and vertebrate-specific ribonuclease superfamily, play important roles in cancer

277 on temperature of the unfolding enthalpy of ribonuclease T1 and the solvation enthalpies of the nonp

278 e, we investigated the refolding reaction of ribonuclease T1 in the presence of the prolyl isomerase

279 Ribonuclease T1 was the only enzyme that preserved ribos

280 le of an ancient extracellular RNase, called Ribonuclease T2 (RNASET2), within the ovarian stromal mi

281 Ribonuclease T2 gene (RNASET2) expression and methylatio

282 attern and functional diversity of mammalian ribonuclease than previously thought.

283 ocyte (MK)-specific knockdown of Dicer1, the ribonuclease that cleaves miRNA precursors into mature m

284 Angiogenin is a stress-activated ribonuclease that cleaves tRNA within anticodon loops to

285 Angiogenin (ANG) is a human ribonuclease that is compromised in patients with amyotr

286 pitated with polynucleotide phosphorylase, a ribonuclease that is responsible for decay of mtRNA tran

287 Angiogenin (ANG) is a ribonuclease that promotes cellular adaptation under str

288 Angiogenin (ANG) is a stress-activated ribonuclease that promotes the survival of motor neurons

289 of translation influences mRNA decay and the ribonucleases that catalyse decay.

290 ural information from chemical probes and/or ribonucleases to restrain RNA secondary structure predic

291 pology related to the RelE family of type II ribonuclease toxins.

292 In some cases, ribonuclease treatment completely degraded ribosome popu

293 Ribonuclease V1 footprinting shows that hADAR2-D protect

294 rtened poly(A) tail is maintained by poly(A) ribonuclease, which associates with CPEB.

295 e, we observed that Sll1130 is a heat-stable ribonuclease whose activity was inhibited by Ssl2245 at

296 to capture 5' monophosphorylated RNA ends in ribonuclease wild-type and mutant strains.

297 this work characterizes a divergent RNase A ribonuclease with a unique expression pattern and functi

298 cium lead to the activation of an endogenous ribonuclease, XendoU.

299 structure of YfcM is similar to that of the ribonuclease YbeY, even though they do not share sequenc

300 Here, we characterized a secreted ribonuclease (Zt6) with an unusual biphasic expression p