ライフサイエンスコーパス: ribonuclease P

1 of the RNA component of Thermotoga maritima ribonuclease P.

2 ly understanding the overall architecture of ribonuclease P.

3 heir discovery of RNA catalysts in bacterial ribonuclease P (an enzyme catalyzing 5' maturation of tR

4 ocessing of precursor transfer RNA (tRNA) by ribonuclease P as a model system.

5 mponents-such as the RNA moiety of bacterial ribonuclease P-can sometimes be replaced with a highly d

6 Ribonuclease P cleaves 5'-precursor sequences from pre-t

7 Ribonuclease P complexed with external guide sequence (E

8 Bacterial ribonuclease P contains a catalytic RNA subunit that cle

9 The tRNA processing endonuclease ribonuclease P contains an essential and highly conserve

10 The Ribonuclease P Database is a compilation of ribonuclease

11 The Ribonuclease P Database is a compilation of ribonuclease

12 y active in vitro, i.e. it is a ribozyme.The Ribonuclease P Database is a compilation of ribonuclease

13 The Ribonuclease P Database is a compilation of ribonuclease

14 The ribozyme from bacterial ribonuclease P (denoted P RNA) specifically recognizes t

15 dize with any mRNA and recruit intracellular ribonuclease P for specific degradation of the target mR

16 structure of the catalytic RNA component of ribonuclease P has been well characterized in Bacteria,

17 Ribonuclease P is a ribonucleoprotein complex that catal

18 Ribonuclease P is a ribonucleoprotein, and in bacteria (

19 Ribonuclease P is a ribonucleoprotein, and in bacteria t

20 Ribonuclease P is a ribonucleoprotein, and in bacteria t

21 Ribonuclease P is a ribonucleoprotein, and in bacteria t

22 Ribonuclease P is responsible for the 5'-maturation of t

23 Ribonuclease P is responsible for the removal of leader

24 Ribonuclease P is the endoribonuclease responsible for t

25 Ribonuclease P is the sole endonuclease responsible for

26 A, the catalytic subunit of Escherichia coli ribonuclease P, is accelerated by C5 protein (the protei

27 with MRPP2 and MRPP3, form the mitochondrial ribonuclease P (mt-RNase P) complex that cleaves the 5'

28 The mitochondrial form of ribonuclease P (mt:RNase P) is responsible for 5'-end ma

29 h the protein component of Bacillus subtilis ribonuclease P (P protein) site specifically modified wi

30 conformational dynamics of Bacillus subtilis ribonuclease P protein (P protein) in its folded state,

31 ies have demonstrated that Bacillus subtilis ribonuclease P protein (P protein) is conformationally h

32 Bacillus subtilis ribonuclease P protein (P protein) is predominantly unfo

33 The crystal structure of ribonuclease P protein aRpp29 from the sulfate-reducing

34 The crystal structure of Bacillus subtilis ribonuclease P protein is reported at 2.6 angstroms reso

35 that archaeal aRpp29 is homologous to human ribonuclease P protein Rpp29.

36 The ribozyme from bacterial ribonuclease P recognizes two structural modules in a tR

37 The x-ray crystal structure of a 417-nt ribonuclease P RNA from Bacillus stearothermophilus was

38 universal feature of the catalytic domain of ribonuclease P RNA is a bulged-helix motif within the P1

39 o humans and are likely to interact with the ribonuclease P RNA or other protein subunits are identif

40 This protein binds to ribonuclease P RNA to form a ribonucleoprotein holoenzym

41 RNA subunit of the ribonucleoprotein enzyme ribonuclease P (RNase P (P RNA) contains the active site

42 ysis are delineated for the RNA component of ribonuclease P (RNase P RNA) by a combination of steady-

43 RNA component of the tRNA processing enzyme ribonuclease P (RNase P RNA).

44 Ribonuclease P (RNase P) and RNase MRP are closely relat

45 ion of the tRNA processing ribonucleoprotein ribonuclease P (RNase P) and the mechanism of its intran

46 Bacterial ribonuclease P (RNase P) belongs to a class of enzymes t

47 The RNA component of bacterial ribonuclease P (RNase P) binds to substrate pre-tRNAs wi

48 The protein component of ribonuclease P (RNase P) binds to the RNA subunit, formi

49 Ribonuclease P (RNase P) catalyzes the 5'-end maturation

50 Bacterial ribonuclease P (RNase P) catalyzes the cleavage of 5' le

51 Ribonuclease P (RNase P) catalyzes the maturation of the

52 Ribonuclease P (RNase P) complexed with external guide s

53 Ribonuclease P (RNase P) contains a catalytic RNA that c

54 The structure of the Escherichia coli ribonuclease P (RNase P) holoenzyme was investigated by

55 Ribonuclease P (RNase P) is a catalytic ribonucleoprotei

56 Ribonuclease P (RNase P) is a common tRNA processing enz

57 Ribonuclease P (RNase P) is a Mg2+-dependent endoribonuc

58 Ribonuclease P (RNase P) is a ribonucleoprotein (RNP) en

59 Ribonuclease P (RNase P) is a ribonucleoprotein complex

60 Ribonuclease P (RNase P) is a ribonucleoprotein complex

61 Ribonuclease P (RNase P) is a ribonucleoprotein enzyme t

62 Ribonuclease P (RNase P) is a ribonucleoprotein enzyme t

63 Ribonuclease P (RNase P) is a ubiquitous endoribonucleas

64 Ribonuclease P (RNase P) is a ubiquitous ribonucleoprote

65 Ribonuclease P (RNase P) is an endonuclease that catalyz

66 Ribonuclease P (RNase P) is an endonuclease that cleaves

67 Ribonuclease P (RNase P) is an essential endonuclease re

68 Ribonuclease P (RNase P) is an essential endonuclease th

69 Ribonuclease P (RNase P) is an essential endonuclease th

70 Ribonuclease P (RNase P) is an essential enzyme whose ac

71 and the eukaryote nucleus, the endonuclease ribonuclease P (RNase P) is composed of a catalytic RNA

72 Ribonuclease P (RNase P) is one of the first ribozymes d

73 Ribonuclease P (RNase P) is responsible for the generati

74 Ribonuclease P (RNase P) is the endoribonuclease respons

75 Ribonuclease P (RNase P) is the endoribonuclease that ge

76 Ribonuclease P (RNase P) is the ribonucleoprotein endonu

77 In eukaryotes, ribonuclease P (RNase P) requires both RNA and protein c

78 The RNA subunit of bacterial ribonuclease P (RNase P) requires high concentrations of

79 The ribonuclease P (RNase P) ribozyme is an endonuclease tha

80 ction procedure, we have previously isolated ribonuclease P (RNase P) ribozyme variants that efficien

81 ive different RNAs: tRNA, 5S rRNA, bacterial ribonuclease P (RNase P) RNA, eukaryotic small subunit r

82 , P protein is the noncatalytic component of ribonuclease P (RNase P) that is critical for achieving

83 , the protein component of Bacillus subtilis ribonuclease P (RNase P) was overproduced in Escherichia

84 polypeptide and an RNA structural motif with ribonuclease P (RNase P), a nuclear endoribonuclease ori

85 Ribonuclease P (RNase P), a ribonucleoprotein (RNP) comp

86 Escherichia coli ribonuclease P (RNase P), a ribonucleoprotein complex wh

87 re like a pre-tRNA and recruit intracellular ribonuclease P (RNase P), a tRNA processing enzyme, to d

88 Bacterial ribonuclease P (RNase P), an enzyme involved in tRNA mat

89 0 is an essential component of mitochondrial Ribonuclease P (RNase P), an enzyme required for mitocho

90 Bacillus subtilis ribonuclease P (RNase P), composed of a catalytically ac

91 A single enzyme, ribonuclease P (RNase P), processes the 5' ends of tRNA

92 The universality of ribonuclease P (RNase P), the ribonucleoprotein essentia

93 ing in the most highly conserved P4 helix of ribonuclease P (RNase P), the ribonucleoprotein that cat

94 es induced in substrates by Escherichia coli ribonuclease P (RNase P), we have incorporated an inters

95 probe functions of conserved nucleobases in ribonuclease P (RNase P).

96 Ribonuclease P (RNaseP) catalyses the removal of the 5'-

97 Ribonuclease P Database is a compilation of ribonuclease P sequences, sequence alignments, secondary

98 Ribonuclease P Database is a compilation of ribonuclease P sequences, sequence alignments, secondary

99 Ribonuclease P Database is a compilation of ribonuclease P sequences, sequence alignments, secondary

100 Ribonuclease P Database is a compilation of ribonuclease P sequences, sequence alignments, secondary

101 1-nucleotide specificity domain of an A-type ribonuclease P that differs in secondary and tertiary st

102 The protein subunit of Escherichia coli ribonuclease P (which has a cysteine residue at position