ライフサイエンスコーパス: riboside

1 rylase has little activity on nicotinic acid riboside.

2 ivator 5-aminoimidazole-4-carboxamide-1-beta-riboside.

3 ible on resupplying NAD(+) with nicotinamide riboside.

4 and its metabolite, imidazole-4-acetic acid-riboside.

5 high levels of the O-glucoside of cis-zeatin riboside.

6 4-tetrahydroisoquinoline with 6-chloropurine riboside.

7 agent, 5-aminoimidazole-4-carboxamide (AICA) riboside.

8 O2-methyluridine or 2-pyrimidinone-1-beta-d-riboside.

9 lymerase inhibitor 5,6-dichlorobenzimidazole riboside.

10 n period and the use of the cytokinin zeatin riboside.

11 nicotinamide mononucleotide to nicotinamide riboside.

12 n be converted into analogues of carbocyclic ribosides.

13 n hydrolyze plant hormones such as cytokinin ribosides.

14 , human and mouse A(3)) better than that for ribosides.

15 with a tight-binding inhibitor, diazepinone riboside 1.

16 s precursor viral DNA was sensitive to the L-riboside 1263W94 [5, 6-dichloro-2-(isopropylamino)-1-bet

17 fluorescent probe, 2-aminopurine-2'-O-methyl riboside (2-AP) has been selectively incorporated at ade

18 -isopropylidenetiazofurin (20) or -benzamide riboside (21) followed by hydrolysis and deprotection af

19 >/=90% de and >99% ee) were converted into C-ribosides 29a,b via the Ru-catalyzed ring-closing metath

20 The discovery that a 1,3-diazepinone riboside (4) operated as a tight-binding inhibitor of CD

21 ng trimetrexate and nitrobenzylmercaptpurine riboside 5' monophosphate.

22 riphosphate and 16-fold more potent than the riboside 5'-diphosphate.

23 ntains the substrate analogue 6-chloropurine riboside 5'-monophosphate (6-Cl-IMP) and the NAD analogu

24 constant for inactivation by 6-chloropurine riboside 5'-monophosphate is increased by 3-fold.

25 Interestingly, p-nitrophenyl riboside 5'-phosphate bound to OPRTs with Kd values near

26 ars ago, ZTP (5-aminoimidazole-4-carboxamide riboside 5'-triphosphate), a modified purine biosyntheti

27 )] and modified adenosine (2,6-diaminopurine riboside) 5'-triphosphates were incorporated into BRCA1

28 ymerase inhibitor, 5,6-dichlorobenzimidazole riboside (50 micromol/L), did not affect 1alpha, 25-(OH)

29 ouric acid (TU) and 2-amino-6-mercaptopurine riboside (6-TGR).

30 but the major product was 5'-chlorobenzamide riboside (7, 85%).

31 were inhibited by 5,6-dichlorobenzimidazole riboside, a drug that interferes with the addition of th

32 Nicotinamide riboside, a form of vitamin B3, protects against excitot

33 tant is able to catalyze hydration of purine riboside, a ground-state analog of the reaction.

34 sue, Belenky et al. report that nicotinamide riboside, a new NAD(+) precursor, regulates Sir2 deacety

35 velopment of steatosis in mice, nicotinamide riboside, a precursor of NAD(+) biosynthesis, was added

36 re of any of these mutants to hydrate purine riboside, a reaction carried out by the wild-type enzyme

37 nalogue, and (6S)-hydroxyl-1,6-dihydropurine riboside, a reaction coordinate analogue, have been dete

38 SMC cultures with 5,6-dichlorobenzimidazole riboside, a selective inhibitor of RNA polymerase II, in

39 r study, 5-amino-imidazolecarboxamide (AICA) riboside, a stimulator of AMP kinase, significantly inhi

40 activation by 5-aminoimidazole-4-carboxamide riboside, A769662 or C13 attenuated Kv 1.5 currents in p

41 These ProTides, along with kinetin riboside, activated PINK1 in cells independent of mitoch

42 nosine analog 5-aminoimidazole-4-carboxamide riboside (AICAR) and inhibition by caffeine and Pfizer c

43 treated with 5-amino-4-imidazole carboxamide riboside (AICAR) for the detection of AMPK phosphorylati

44 by exogenous 5-amino-4-imidazolecarboxamide riboside (AICAr) in a AICAr and MTX concentration-depend

45 tor of AMPK, 5-amino-4-imidazole carboxamide riboside (AICAR) inhibited lipopolysaccharide (LPS)-indu

46 of AMPK using 5-aminoimidazole-4-carboxamide riboside (AICAR) inhibited O2-sensitive K+ currents (car

47 ble activator 5-aminoimidazole-4-carboximide riboside (AICAR) is associated with an increase in the o

48 on of AMPK by 5-amino-4-imidazolecarboxamide riboside (AICAR) leads to increased glucose transport.

49 with a pharmacological AMPK activator, AICA-riboside (AICAR) resulted in a time- and concentration-d

50 ative stress, 5-aminoimidazole-4-carboxamide riboside (AICAR), a pharmacological activator of AMPK, i

51 tor, 5-aminoimidazole-4-carboxamide-1-beta-d-riboside (AICAR), activated PYK2, ERK and aPKCs; (b) eff

52 ma cells with 5-aminoimidazole-4-carboxamide riboside (AICAR), an agent that activates AMP-activated

53 5-Aminoimidazole-4-carboxamide riboside (AICAR), an agent with diverse pharmacological

54 ug metformin, 5-aminoimidazole-4-carboxamide riboside (AICAR), and ischemia, well established trigger

55 imetic agent, 5-aminoimidazole-4-carboxamide riboside (AICAR), by the antidiabetic drug phenformin, o

56 tor of AMPK, 5-amino-4-imidazole carboxamide riboside (AICAR), inhibited oxidative stress-induced pho

57 K) activator, 5-aminoimidazole-4-carboxamide riboside (AICAR), on tumor necrosis factor alpha (TNF-al

58 MPK activator 5-aminoimidazole-4-carboxamide riboside (AICAR).

59 vation (using 5-aminoimidazole-4-carboxamide riboside [AICAR]) induces raptor phosphorylation and inh

60 to efficiently use exogenous aminoimidazole riboside (AIRs) as a source of thiamine.

61 and other aldoses) to give a mixture of four ribosides: alpha and beta pyranosides and furanosides.

62 nicotinamide mononucleotide and nicotinamide riboside also increases NAD(+) levels in astrocytes.

63 stration of 5-aminoimidazole-4-carboxamide-1-riboside also prevented renal hypertrophy, glomerular ba

64 AICA riboside also triggered GVB when meiotic arrest was main

65 -4-carboxamide 1-beta-d-ribofuranoside (AICA riboside), an activator of AMPK, was tested on denuded o

66 -4-carboxamide-1-beta-D-ribofuranoside (AICA-riboside), an analog of adenosine, is taken up into cell

67 Conversely, 5-aminoimidizole-4-carboxamide riboside, an activator of AMPK, promotes transepithelial

68 at addition of 5-amino-imidazole carboxamide riboside, an AMPK activator, to WGA and human hepatocyte

69 activated by 5-aminoimidazole-4-carboxamide riboside, an AMPK agonist, these data indicate that RNS

70 supplementation of a diet with nicotinamide riboside, an NAD precursor, replenished hepatic NADP and

71 Using purine riboside analogues labeled with 15N1 or 13C6 and the the

72 onstrained 2',3'-epoxide derivatives in both riboside and (N)-methanocarba series 13 and 21, respecti

73 ereoselective synthesis of beta-nicotinamide riboside and a series of related amide, ester, and acid

74 K activators 5-amino-4-imidazole carboxamide riboside and A769662 suppressed MMP-9 expression in WT M

75 n by A769662, 5-aminoimidazole-4-carboxamide riboside and C13 and by intracellular dialysis from a pa

76 inhibitors such as 5,6-dichlorobenzimidazole riboside and camptothecin can substantially block VM-26-

77 uman cells, Nrk2 phosphorylates Nicotinamide Riboside and generates NAD+ through an alternative salva

78 Creatine riboside and NANA may be robust urinary clinical metabol

79 Here, we show that nicotinamide riboside and nicotinic acid riboside are authentic intra

80 Recently, we discovered that nicotinamide riboside and nicotinic acid riboside are biosynthetic pr

81 e responsible for production of nicotinamide riboside and nicotinic acid riboside in cells.

82 ators such as 5-aminoimidazole-4-carboxamide riboside and phenformin.

83 specific for phosphorylation of nicotinamide riboside and the cancer drug tiazofurin.

84 dichloro-1-beta-D-ribofuranosylbenzimidazole riboside and trastuzumab, but not between inhibitors of

85 the presence of aminoimidazole-4-carboxamide riboside and/or after alpha1AMP-activated protein kinase

86 ated levels of certain purine and pyrimidine ribosides and cytokinins that reflect the substrate pref

87 chloro-1-beta-D-riborfuranosyl benzimidazole riboside) and TCRB (2,5,6-trichloro-1-beta-D-riborfurano

88 o-inositol and IAA-glucan, but not by zeatin riboside, and only weakly by gibberellic acid, abscisic

89 els of nicotinamide riboside, nicotinic acid riboside, and other NAD(+) metabolites were determined b

90 ethylnicotinate riboside, O-methylnicotinate riboside, and several N-alkyl derivatives increased NAD+

91 cis-Zeatin, cis-zeatin riboside, and their O-glucosides were detected in all ma

92 tors such as 5-amino-imidazole-4-carboxamide riboside, antimycin A, and sodium azide inhibited cell g

93 hat nicotinamide riboside and nicotinic acid riboside are authentic intracellular metabolites in yeas

94 hat nicotinamide riboside and nicotinic acid riboside are biosynthetic precursors of NAD(+), which ar

95 nicotinamide mononucleotide and nicotinamide riboside are reported to confer resistance to metabolic

96 n, we identified the plant cytokinin kinetin riboside as an inhibitor of CCND2 trans-activation.

97 ts reaction with adenosine generated kinetin riboside, as confirmed by comparing the MS/MS profiles o

98 A stem-loop RNA with p-nitrophenyl O-riboside at the depurination site is not a substrate, bu

99 ichloro-1-beta-d-ribofuranosyl benzimidazole riboside (BDCRB) was used to allow the accumulation of h

100 ichloro-1-beta-d-ribofuranosyl benzimidazole riboside (BDCRB) were characterized by nanoparticle trac

101 ichloro-1-beta-d-ribofuranosyl benzimidazole riboside (BDCRB)-treated cultures and purified by tangen

102 A member of the family of L-riboside benzimidazole compounds, 1263W94, was shown rec

103 The nicotinamide riboside binding site overlaps that of the substrate gal

104 mide riboside kinase and that nicotinic acid riboside bioavailability is increased by ester modificat

105 kinase 2 inhibitor 5,6-dichlorobenzimidazole riboside but not, however, by the PI3K inhibitor wortman

106 rd growth conditions, Nrt1, the nicotinamide riboside carrier, is the major AICAr transporter in yeas

107 g actinomycin D or 5,6-dichlorobenzimidazole riboside collagen alpha1(I) mRNA has estimated half-live

108 tions produce predominantly the beta-methoxy riboside compound, with a relative nucleophilicity of Me

109 Benzimidazole riboside compounds represent a new class of antiviral co

110 e activation by aminoimidazole-4-carboxamide riboside counteracted lipopolysaccharide-induced hyperpe

111 2,6-Diaminopurine-riboside (DAP), 7-deazaguanosine (7-deaza-G), and 7-meth

112 Among 9-riboside derivatives, only N(6)-cyclopentyl and 7-norbor

113 growth factor beta, or dichlorobenzimidazole riboside did not result in significant increases in spon

114 he CKII inhibitor, 5,6-dichlorobenzimidazole riboside, did not affect etoposide-stabilized topo II-DN

115 y actinomycin D or 5,6-dichlorobenzimidazole riboside (DRB) causes VHL to be redistributed to the nuc

116 y actinomycin D or 5,6-dichlorobenzimidazole riboside (DRB).

117 Nicotinamide riboside efficiently rescues NAD(+) synthesis in respons

118 lorie restriction in the mouse, nicotinamide riboside elevates NAD(+) and increases Sir2 function.

119 Nicotinamide riboside elevates NAD+ levels via the nicotinamide ribos

120 phenformin or 5-aminoimidazole-4-carboxamide-riboside elicited discrete Ca2+ signaling mechanisms in

121 the Golgi, because 5,6-dichlorobenzimidazole riboside, emetine, and brefeldin A inhibited the increas

122 lementation of yeast cells with nicotinamide riboside extends replicative lifespan and increases Sir2

123 inhibitor platform 5-(formylamino)imidazole riboside (FAIRs, 4) was designed by removal of the-C6(OH

124 Incorporation of the C-riboside formycin A at the depurination site provides an

125 ic base pair analogs (inosine, diaminopurine riboside, guanosine, or adenosine paired with U, C, or i

126 imetic AICAR (5-aminoimidazole-4-carboxamide riboside) has been shown to inhibit hepatic gluconeogene

127 se is 100-fold more active as a nicotinamide riboside hydrolase than as a uridine hydrolase and that

128 Hst1, and Rfm1, fully restores nicotinamide riboside import and utilization when resupplied to mutan

129 of nicotinamide riboside and nicotinic acid riboside in cells.

130 Meiotic induction by AICA riboside in dbcAMP-supplemented medium was initiated wit

131 of AMPK by 5-aminoimidazole-4-carboxamide-1-riboside in OVE26 mice attenuated Nox4 and p53 expressio

132 uptake observed with AMPK activation by AICA-riboside in perfused rat hindlimb muscles is due to an i

133 ue formation of a C-riboside instead of an N-riboside in the condensation of p-aminobenzoic acid (pAB

134 n does not cause a decrease in the CK zeatin riboside in the xylem sap or a strong increase in RMS1 t

135 nistration of 5-aminoimidazole-4-carboxamide riboside in Vasp(-/-) mice reduced hepatic steatosis and

136 Nrk-independent utilization of nicotinamide riboside in yeast.

137 8-nitro-1,2,3,4-tetrahydroisoquinolylpurine ribosides, in which the nitrobenzyl moiety in NBMPR has

138 MPK activator 5-aminoimidazole-4-carboxamide-riboside increased AMPK activity twofold and completely

139 Kinetin riboside induced marked suppression of CCND2 transcripti

140 Similarly, purine riboside inhibitors of ADA that prefer the N hemisphere

141 ngdom; one preferentially targets the purine ribosides inosine and xanthosine, while the other is mor

142 nthase catalyzes the unique formation of a C-riboside instead of an N-riboside in the condensation of

143 e cytokinin [N6-(Delta2 isopentenyl) adenine riboside] (iPR).

144 In eukaryotes, nicotinamide riboside is a newly discovered NAD(+) precursor that is

145 Nicotinamide riboside is a recently discovered eukaryotic NAD(+) prec

146 trient in milk, suggesting that nicotinamide riboside is a useful compound for elevation of NAD+ leve

147 xperimentally and revealed that nicotinamide riboside is an unanticipated NAD+ precursor in yeast.

148 uptake observed with AMPK activation by AICA-riboside is due to GLUT4 translocation from an intracell

149 shown that exogenously supplied nicotinamide riboside is imported into yeast cells by a dedicated tra

150 e reaction and a C-riboside rather than an N-riboside is the product.

151 The mechanism of action of nicotinamide riboside is totally dependent on increased net NAD(+) sy

152 Creatine riboside (IUPAC name: 2-{2-[(2R,3R,4S,5R)-3,4-dihydroxy-

153 Here we show that nicotinamide riboside kinase 1 (NRK1) is necessary and rate-limiting

154 tinamide precursor, whereas the nicotinamide riboside kinase 2 (NMRK2) that phosphorylates the nicoti

155 We found that Nicotinamide riboside kinase 2b (Nrk2b) cell autonomously modulates t

156 We find that nicotinamide riboside kinase 2b-mediated NAD+ biosynthesis, which fun

157 epends on uridine hydrolase and nicotinamide riboside kinase and that nicotinic acid riboside bioavai

158 de elevates NAD+ levels via the nicotinamide riboside kinase pathway and by a pathway initiated by sp

159 sor converted to NAD(+) via the nicotinamide riboside kinase pathway and by nucleosidase activity and

160 se is responsible for mammalian nicotinamide riboside kinase-independent nicotinamide riboside utiliz

161 Nicotinamide riboside kinases from yeast and humans essential for thi

162 mide mononucleotide by specific nicotinamide riboside kinases, Nrk1 and Nrk2.

163 We characterized a single compound, kinetin riboside (KR), on AML L-ICs and HSPCs.

164 s with apigenin or 5,6-dichlorobenzimidazole riboside led to a rapid decrease in NKX3.1 accumulation

165 cause current data suggest that nicotinamide riboside may be the only vitamin precursor that supports

166 The adenosine moiety and the nicotinamide riboside moiety are both in the anti conformation about

167 The anti conformation of the nicotinamide riboside moiety is in accord with the preferred conforma

168 of activity, suggesting that the nicotinate riboside moiety is recognized as a neutral zwitterion.

169 ion by NAIM using 5'-O-(1-thio)diaminopurine riboside monophosphate (DMP alphaS), an adenosine analog

170 p into cells and phosphorylated to form AICA-riboside monophosphate (ZMP), which can also activate AM

171 evels of trans-zeatin riboside, trans-zeatin riboside monophosphate and isopentenyladenine 9-glucosid

172 icotinamide riboside (NR) and nicotinic acid riboside (NAR) are the major precursors for NAD biosynth

173 reased the S6-(4-nitrobenzyl)-mercaptopurine riboside (NBMPR) IC50 values by approximately 4- and 6-f

174 the ENT1 inhibitor nitrobenzylmercaptopurine riboside (NBMPR) in intact cells.

175 th antifolates and nitrobenzylmercaptopurine riboside (NBMPR), a potent inhibitor of the es nucleosid

176 ransporter ligand, nitrobenzylmercaptopurine riboside (NBMPR), designed for probing its bound (bioact

177 cDNA encoding the nitrobenzylmercaptopurine riboside (NBMPR)-insensitive, equilibrative nucleoside t

178 ype ENT1 inhibitor nitrobenzylmercaptopurine riboside (NBMPR).

179 osine uptake using nitrobenzylmercaptopurine riboside (NBMPR).

180 he simultaneous quantitation of nicotinamide riboside, nicotinamide mononucleotide and NAD in milk by

181 ay, and intracellular levels of nicotinamide riboside, nicotinic acid riboside, and other NAD(+) meta

182 Nicotinamide riboside, nicotinic acid riboside, O-ethylnicotinate rib

183 Administration of nicotinamide riboside (NmR) has been shown to ameliorate deficiencies

184 Nicotinamide riboside (NmR) is a key pyridine metabolite that is excr

185 cotinic acid, nicotinamide, and nicotinamide riboside (NmR), via multiple enzymatic steps.

186 In this study, we explored whether the ribosides NR and NAR can be generated in human cells.

187 d prediabetic and T2D mice with nicotinamide riboside (NR) added to HFD.

188 Addition of NA or nicotinamide riboside (NR) allows a moved mother to maintain replicat

189 entation with the NAD-precursor nicotinamide riboside (NR) ameliorates energetic derangement and symp

190 e and nicotinic acid as well as nicotinamide riboside (NR) and nicotinic acid riboside (NAR) are the

191 The activity of nicotinamide riboside (NR) in neuroprotective models and the recent d

192 namide mononucleotide (NMN) and nicotinamide riboside (NR) in the amidated salvage pathway despite no

193 Nicotinamide riboside (NR) is an endogenously produced key pyridine m

194 Nicotinamide riboside (NR) is in wide use as an NAD(+) precursor vita

195 lly, deletion of SSY5 increases nicotinamide riboside (NR) levels and phosphate-responsive (PHO) sign

196 Restoring NAD(+) pools with nicotinamide riboside (NR) prevents DNA damage and tumor formation.

197 The gene for the nicotinamide riboside (NR) transporter (pnuC) was identified in Haemo

198 liver regeneration, we supplied nicotinamide riboside (NR), an NAD precursor, in the drinking water o

199 inamide mononucleotide (NMN) or nicotinamide riboside (NR), protects against metabolic disease, neuro

200 id (NA), nicotinamide (NAM) and nicotinamide riboside (NR).

201 icotinamide, nicotinic acid, or nicotinamide riboside (NR).

202 Dihydronicotinamide riboside (NRH):quinone oxidoreductase 2 (NQO2) is a flav

203 Nicotinamide riboside, nicotinic acid riboside, O-ethylnicotinate riboside, O-methylnicotinate

204 , nicotinic acid riboside, O-ethylnicotinate riboside, O-methylnicotinate riboside, and several N-alk

205 he trans isomer, although cis-zeatin and its riboside occur as major components in some plant species

206 ent facilitator with a K(m) for nicotinamide riboside of 22 microm.

207 fects of the sirtuin activator, nicotinamide riboside, on NLRP3 inflammasome activation.

208 ocytes, 8 mmol/l glucose, and +/-2 mmol/AICA-riboside or +/-60 nmol/l insulin.

209 of AMPK with 5-aminoimidazole-4-carboxamide riboside or salicylate increased nNOS S1412 phosphorylat

210 Furthermore, 5-aminoimidizole-4-carboxamide riboside partially protects the tight junctions from dis

211 t the synthesis of a novel 2'-O-methyl (OMe) riboside phosphoramidite derivative of the G-clamp tricy

212 cue of 8-azaadenosine (pK(a) 2.2) and purine riboside (pK(a) 2.1) interference at A756 at reduced rea

213 y of nucleoside analogs [inosine (I), purine riboside (PR), 2-aminopurine (2-AP), 2,6-diaminopurine (

214 (NMRK2) that phosphorylates the nicotinamide riboside precursor is increased, to a higher level in th

215 tinic acid mononucleotide and nicotinic acid riboside production are also uncovered that further unde

216 y, we discovered that exogenous nicotinamide riboside promotes Sir2-dependent repression of recombina

217 um stability, and hydrolysis of four kinetin riboside ProTides.

218 P450 reductase (P450R), dihydronicotinamide riboside:quinone oxidoreductase 2 (NQO2), and xanthine o

219 xidoreductase (NQO1) and dihydronicotinamide riboside:quinone oxidoreductases (NQO2) are cytosolic fl

220 tes (pAB) occurs during the reaction and a C-riboside rather than an N-riboside is the product.

221 sing the inhibitor nitrobenzylmercaptopurine riboside recapitulated the RBV-resistant phenotype in RB

222 ewly identified NAD+ precursor, nicotinamide riboside, reviewed herein, are responsible for vitamin-s

223 Additionally, the two nicotinamide riboside salvage pathways contribute to NAD(+) metabolis

224 rba (i.e., of the Northern conformation) and riboside series 18 and 5, respectively, were potent anta

225 groups that enhance A(3)AR affinity in the 9-riboside series, including those that reduce intrinsic e

226 The 5-aminoimidazole-4-carboxamide riboside served to study the impact of AMP-activated pro

227 Degradation of natural nucleic acid ribosides, such as ATP, using periodate oxidation simpli

228 we present prospects for human nicotinamide riboside supplementation and propose areas for future re

229 Accordingly, we show that nicotinamide riboside supplementation in food attenuates the developm

230 Nicotinamide riboside supplementation of yeast extends replicative li

231 +) metabolism in the absence of nicotinamide-riboside supplementation.

232 Zebularine is a riboside that must undergo a complex metabolic transform

233 The data show that nicotinamide riboside, the most energy-efficient among NAD precursors

234 Nicotinamide riboside, the most recently discovered form of vitamin B

235 The ability of nicotinamide riboside to enhance life span does not depend on calorie

236 growth factor beta, or dichlorobenzimidazole riboside to the medium.

237 ts accumulated higher levels of trans-zeatin riboside, trans-zeatin riboside monophosphate and isopen

238 9-Ribosides transformed into the ring-constrained (N)-meth

239 Nicotinamide riboside treatment also robustly increases the myocardia

240 Mechanistically, kinetin riboside upregulated expression of transcription repress

241 The molecular basis for nicotinamide riboside uptake was unknown in any eukaryote.

242 single gene, YOR071C, abrogates nicotinamide riboside uptake without altering nicotinic acid or nicot

243 suggesting a similar basis for nicotinamide riboside uptake.

244 -1r was prepared from 2-amino-6-chloropurine riboside using adenosine deaminase.

245 Finally, we show that yeast nicotinic acid riboside utilization largely depends on uridine hydrolas

246 ide riboside kinase-independent nicotinamide riboside utilization.

247 Secreted nicotinamide riboside was detected with a biological assay, and intra

248 Nicotinamide riboside was discovered as a nutrient in milk, suggestin

249 Perfusion medium containing AICA-riboside was found to significantly increase AMPK activi

250 Creatine riboside was the strongest classifier of lung cancer sta

251 Smaller and variable amounts of trans-zeatin riboside were also recovered.

252 at P2Y(1) receptors, while the corresponding ribosides were inactive.

253 chloro-1-beta-D-riborfuranosyl benzimidazole riboside) were the first compounds shown to inhibit clea

254 cleoside phosphorylase cleave nicotinic acid riboside, whereas the yeast phosphorylase has little act

255 fect the bovine milk content of nicotinamide riboside, whereas UHT processing fully destroyed the vit

256 s blocked by 5-amino imidazole-4-carboxamide riboside (which is converted to an AMP-mimetic) or the p

257 ) confers high hydrolase activity for purine ribosides, while an aspartate residue in this position c

258 s also shown to synthesize 2,6-diaminopurine riboside with a catalytic efficiency (1.4 x 10(6) M-1 s-

259 Maribavir is an oral benzimidazole riboside with potent in vitro activity against cytomegal

260 larity of the complex with the dihydropurine riboside with that of an identical complex previously de