ライフサイエンスコーパス: ribosomal

1 ures of E. coli RNAP core bound to the small ribosomal 30S subunit.

2 It allows binding of the tRNAs to the ribosomal A and P sites, but prevents correct positionin

3 rotein synthesis by cleaving mRNA within the ribosomal A site.

4 post-trimming modification characteristic of ribosomal and guide RNAs.

5 In contrast, ribosomal and histone datasets, which are most commonly

6 hacid subfamily Delphacinae based on nuclear ribosomal and mitochondrial DNA sequences of four geneti

7 oretic analysis shows that compared to other ribosomal antibiotics, MTM and PKM prevent synthesis of

8 fficiency of this synthesis, suggesting that ribosomal architecture has been shaped by evolutionary p

9 brought to our current understanding of the ribosomal assembly process in bacteria using previous de

10 of G3BP1 do not occur solely through RNA or ribosomal binding but require both the RRM and RGG domai

11 The c-myc oncogene stimulates ribosomal biogenesis and protein synthesis to promote ce

12 the Pf1-associated chromatin complex in the ribosomal biogenesis and senescence pathways.

13 ighly preferred specimen orientation, and of ribosomal biogenesis intermediates, which adopt moderate

14 and the target of rapamycin (TOR)-regulated ribosomal biogenesis pathway, which might underlie a cel

15 A dynamic ribosomal biogenesis response is not required for IGF-1-

16 Despite robust inhibition of the dynamic ribosomal biogenesis response to IGF-1, myotube diameter

17 s c-Myc-dependent rDNA transcription key for ribosomal biogenesis.

18 perones on protein folding and show that the ribosomal chaperone trigger factor acts as a mechanical

19 We analyzed the complete nuclear ribosomal cistron, the complete chloroplast genome, a pa

20 Selection of a library of modified ribosomal clones with phosphorylated puromycin identifie

21 ation and (iii) dissociates post-termination ribosomal complexes that are devoid of the nascent pepti

22 have identified mutations in genes encoding ribosomal components in Mycobacterium smegmatis that con

23 inant of binding to the canonical eukaryotic ribosomal decoding center.

24 nd RF2 induces conformational changes in the ribosomal decoding centre that are similar to those seen

25 es of the nucleobases, and the mechanisms of ribosomal decoding contributed to the position-dependent

26 Together, these results suggest that ribosomal deficiency contributes to impaired megakaryopo

27 al footprints on coding sequences, 5' leader ribosomal densities, distribution of ribosomes along cod

28 erns of apoptosis and associated dynamics of ribosomal disassembly, calcium overload and mitochondria

29 y elevated H3.3 occupancy, including the 45S ribosomal DNA (45S rDNA) loci, where loss of ATRX result

30 liana, 45S rRNA genes are found in two large ribosomal DNA (rDNA) clusters and little is known about

31 etrotransposons, and noncoding RNAs from the ribosomal DNA (rDNA) intergenic spacers, consistent with

32 lar mechanisms for SUMO-dependent control of ribosomal DNA (rDNA) silencing through the opposing acti

33 plify nucleolar targeting of FGFR2, activate ribosomal DNA (rDNA) transcription and delay differentia

34 etitive sequences, including centromere, 45S ribosomal DNA (rDNA), knob, and telomere repeats.

35 Here, nonnative rRNA gene [ribosomal DNA (rDNA)] copies were identified in a set of

36 ves of silencing loss in the heterochromatic ribosomal DNA during the early phases of aging, followed

37 cassettes, and synXII, specifically when the ribosomal DNA is moved to another chromosome.

38 nscribed spacer (ITS) as one part of nuclear ribosomal DNA is one of the most extensively sequenced m

39 ernal transcribed spacer (ITS) region of the ribosomal DNA is the conventional marker region for fung

40 t of the nucleolar remodeling complex to the ribosomal DNA promoter.

41 rk of Theaceae based on plastome and nuclear ribosomal DNA sequence data, the temporal history of the

42 munity production, with high-throughput 18 S ribosomal DNA sequencing to elucidate the relationship b

43 d microbiota composition was analyzed by 16S ribosomal DNA sequencing.

44 ynthesis, ribonucleotide levels, and affects ribosomal DNA stability, leading to the formation of a n

45 l of cytidine deaminase-deficient cells, and ribosomal DNA transcription and stability.

46 omponents fail to assemble in the absence of ribosomal DNA, whereas the thermodynamically driven comp

47 components differ in their requirements for ribosomal DNA; the two actively assembling components fa

48 ation by binding to overlapping sites in the ribosomal exit tunnel.

49 biophysical modeling, we determined that the ribosomal footprint extends 13 nucleotides into the N-te

50 ture overlaps or partially overlaps with the ribosomal footprint, the free energy to unfold only the

51 translational response, including density of ribosomal footprints on coding sequences, 5' leader ribo

52 Synthesis of a proportion of non-ribosomal frameshift derived GagPol would be relevant in

53 ni but unique in their C termini due to a -1 ribosomal frameshift during translation.

54 d of the gag gene performing a programmed -1 ribosomal frameshift event to enter the overlapping pol

55 d related alphaviruses utilize programmed -1 ribosomal frameshifting (-1 PRF) to synthesize the viral

56 ATP7B, the human homolog of copA, and direct ribosomal frameshifting in vivo.

57 Programmed -1 ribosomal frameshifting is a mechanism of gene expressio

58 shift/slippage site, which is important for ribosomal frameshifting, is shown here to limit reverse

59 shifted registers reminiscent of programmed ribosomal frameshifting.

60 Aminoglycoside antibiotics interfere with ribosomal function and may cause codon misreading.

61 Here, we identify an extra-ribosomal function for uS12/Rps23 central to this regula

62 The ribosomal gene cluster (rDNA) on synXII was left intact

63 le variable (V) regions of the bacterial 16S ribosomal gene, to interrogate microbial profiles in ter

64 mosomes combined with cytogenetic mapping of ribosomal genes and Hox paralogs and with microsatellite

65 xecuted, the suppression of transcription of ribosomal genes and upregulation of lineage-specific fac

66 . pulchra mitochondrial genome contains both ribosomal genes, 21 tRNAs, but only 11 protein-coding ge

67 Using seven chloroplast and nuclear ribosomal genes, we constructed a phylogeny of 5036 spec

68 By using DNA barcoding of nuclear ribosomal internal transcribed spacer (ITS) of the rRNA

69 immunogenic peptide within the mycobacterial ribosomal large subunit protein RplJ, encoded by the Rv0

70 Ribosomal loss of RACK1, which excludes TDP-43 from the

71 They are major components of the ribosomal machinery for protein synthesis and they also

72 Thus, ribosomal mutations can serve as stepping-stones in an e

73 Importantly, while these ribosomal mutations have a fitness cost in antibiotic-fr

74 nascent peptides that remain stalled in 60S ribosomal particles due to a dysfunction in translation

75 Three-dimensional structures of ribosomal particles from Staphylococcus aureus obtained

76 The RH50 protein comigrates with ribosomal particles, and is required for efficient trans

77 protein synthesis and they also serve in non-ribosomal pathways for regulation and signaling metaboli

78 SMAD-binding domain of ZEB2 protein induces ribosomal pausing and compromises protein synthesis.

79 on conflicts, with RelA activation requiring ribosomal pausing.

80 clization inspired by the cyclization of non-ribosomal peptide aldehydes is presented.

81 ons that upregulate transcription of the non-ribosomal peptide synthetase gene required for nidulanin

82 ved in the posttranslational modification of ribosomal peptides, and transferases from various biosyn

83 presentation was restricted to the defective ribosomal product (DRiP) form of the protein.

84 ion reveals that ubiquitylation of defective ribosomal products is rate limiting in generating class

85 Ribosomal profiling in rat showed the translational foot

86 Thus, ribosomal profiling provides valuable insights into tran

87 abortive RNA in initiation from short-lived ribosomal promoter OCs are well described by a quantitat

88 Ribosomal protein (RP) gene mutations, mostly associated

89 Ribosomal protein (RP) genes must be coordinately expres

90 most often due to heterozygous mutations in ribosomal protein (RP) genes that lead to defects in rib

91 As with concomitant stabilization, including ribosomal protein (RP) mRNAs.

92 To determine the contribution of the ribosomal protein (RP)-murine double minute 2 (MDM2)-p53

93 -dependent upregulation of mitochondrial 37S ribosomal protein 1/ATP-binding cassette subfamily C mem

94 logical culture, nucleic acid amplification, ribosomal protein characterization, and genome sequencin

95 A new study shows that splitting ribosomal protein content into many small, similarly siz

96 RNA molecules dominate the mass and why the ribosomal protein content is divided into 55-80 small, s

97 gulates nutrient-dependent downregulation of ribosomal protein encoding RNAs, leading to the redistri

98 cation of CD4(+) T cell responses to defined ribosomal protein epitopes expands the range of antigeni

99 ignature, which is associated with defective ribosomal protein function and linked to the erythroid l

100 t of cells appears to decouple expression of ribosomal protein genes from the environmental stress re

101 bundant class of intron-containing RNAs (the ribosomal protein genes) to Mer1-regulated transcripts.

102 dates identified in this search included two ribosomal protein genes, RPL35a and RPL23, and ferredoxi

103 p of human disorders most commonly caused by ribosomal protein haploinsufficiency or defects in ribos

104 d identified, namely enolase, cyclophilin-A, ribosomal protein L13 and actin-1.

105 mic distribution of box C/D snoRNAs from the ribosomal protein L13a (Rpl13a) locus.

106 conventional organelles, colocalize with the ribosomal protein L22, and cluster the WNK signaling pat

107 We report the crystal structure of ribosomal protein L4 (RpL4) bound to its dedicated assem

108 iptomic analyses show progressive changes in ribosomal protein levels and mitochondrial function as e

109 ities were also correlated with the cellular ribosomal protein levels, thereby suggesting that mRNA p

110 ppressed the expression of the mitochondrial ribosomal protein MRPS10 and reduced 12S ribosomal RNA (

111 tivity of specific cells and tissue types to ribosomal protein mutations.

112 LARP4 is a posttranscriptional regulator of ribosomal protein production in mammalian cells and sugg

113 duration of feast and the allocation of the ribosomal protein reserve to maximize the overall gain i

114 Among these genes ribosomal protein RPL35A, putative RNA helicase DDX24, a

115 Yeast ribosomal protein Rps3/uS3 resides in the mRNA entry cha

116 binds within the carboxy-terminal domain of ribosomal protein S1 (RpsA) and inhibits trans-translati

117 Ribosomal protein S1 forms a wall of the tunnel between

118 that interact with Geobacillus kaustophilus ribosomal protein S15.

119 Ribosomal protein s15a (RPS15A) plays a promotive role i

120 rt novel immunosuppressive properties of the ribosomal protein S19 (RPS19), which is upregulated in h

121 sphate feeding, generate less phosphorylated ribosomal protein S6 (P-S6) than the WT.

122 -LTD, through a mechanism involving mTOR and ribosomal protein S6 activation.

123 was associated with decreased phosphorylated ribosomal protein S6 immunoreactivity.

124 IL-7 treatment increased levels of phospho-ribosomal protein S6 in HIV-specific CD8 T cells, sugges

125 of mammalian target of rapamycin complex 1, ribosomal protein S6 kinase 1, and eukaryotic translatio

126 lular signal-regulated kinase) and S6K-RPS6 (ribosomal protein S6 kinase-ribosomal protein S6) axes.

127 es expressed higher levels of phosphorylated ribosomal protein S6 than paired fibroblasts from normal

128 e) and S6K-RPS6 (ribosomal protein S6 kinase-ribosomal protein S6) axes.

129 B (trkB), namely, phosphorylation of Akt and ribosomal protein S6, in SN neurons.

130 olecular dynamics simulations show that each ribosomal protein switches the 16S conformation and damp

131 ional regulation is a potential mechanism of ribosomal protein synthesis and stoichiometry.

132 RPS3 is a small ribosomal protein that also has extraribosomal functions

133 ere we report that ubiquitination of the 40S ribosomal protein uS10 by the E3 ubiquitin ligase Hel2 (

134 s mediated by an interaction with a specific ribosomal protein, RACK1, and that an increase in cytopl

135 hosphorylated 4E-binding protein 1, and p-S6 ribosomal protein.

136 ribosomal RNA (rRNA) expansion segments and ribosomal proteins (rProtein).

137 folding and local autonomy of assembly with ribosomal proteins (rProteins), and that the rProtein an

138 ation in eukaryotes created paralog pairs of ribosomal proteins (RPs) that show high sequence similar

139 rocess that involves the ordered assembly of ribosomal proteins and numerous RNA structural rearrange

140 UBE2O recognized ribosomal proteins and other substrates directly, target

141 e nuclear import of approximately 80 nascent ribosomal proteins and the elimination of excess amounts

142 osine [m(7)G] cap of TOP mRNAs, which encode ribosomal proteins and translation factors.

143 Astrocyte ribosomal proteins are found adjacent to synapses in viv

144 Ribosomal proteins are translated in the cytoplasm and i

145 ble for import can maintain the stability of ribosomal proteins by neutralizing unfavorable positive

146 control that involves the ubiquitination of ribosomal proteins by the E3 ubiquitin ligase Hel2/RQT1.

147 osomes drive cell growth, but translation of ribosomal proteins competes with production of non-ribos

148 Accordingly, approximately 25% of ribosomal proteins expressed in rapidly growing cells do

149 oning the assembly site, and dissociation of ribosomal proteins from karyopherins.

150 Among 79 ribosomal proteins in yeast, only a few are identified w

151 munoprecipitates with RNA polymerase I, with ribosomal proteins RPL26 and RPL24, and with components

152 We identified two specific ribosomal proteins that are strictly required for flaviv

153 osomes involves the hierarchical addition of ribosomal proteins that progressively stabilize the fold

154 We also identified ribosomal proteins under relaxed or neutral selection.

155 le molecule FRET to show how combinations of ribosomal proteins uS4, uS17 and bS20 in the 16S 5' doma

156 Numerous ribosomal proteins were identified, confirming the work

157 ransferase center, and stable association of ribosomal proteins with rRNA surrounding the polypeptide

158 We find that cells produce excess ribosomal proteins, amounting to a constant approximatel

159 d iPSS in the polycistronic operons encoding ribosomal proteins, and the majority upstream and proxim

160 on and metabolism, as well as those encoding ribosomal proteins, DNA and histone-modifying enzymes an

161 er acetylation occupancy and lower levels of ribosomal proteins, including those involved in ribosome

162 ncing of Rps19, but not several other tested ribosomal proteins, indicating distinct cellular respons

163 In addition to downregulating ribosomal proteins, p17 reduces mTORC2 assembly and disr

164 lision in vivo resulted in ubiquitination of ribosomal proteins, suggesting that collision is sensed

165 that encode translation machinery, including ribosomal proteins, was upregulated during the T cell cl

166 ensity, which affected mostly mRNAs encoding ribosomal proteins.

167 karyotic ribosomes are composed of rRNAs and ribosomal proteins.

168 mal proteins competes with production of non-ribosomal proteins.

169 d down-regulation of genes encoding rRNA and ribosomal proteins.

170 gger site-specific ubiquitination on several ribosomal proteins.

171 ocesses: RNA processing; gene transcription; ribosomal proteins; protein degradation; and metabolism

172 nd yUtp23/hUTP23 are essential for early pre-ribosomal (r)RNA cleavages at sites A0, A1/1 and A2/2a i

173 q is often hampered by the high abundance of ribosomal (r)RNA in bacterial cells.

174 results, the proximity of the 3' end to the ribosomal recruitment site of the mRNA could induce a fe

175 S RNA binding domain and G3BP1 RNA (RRM) and ribosomal (RGG) binding domains showed that sigmaNS asso

176 ent assay (ELISA), and the microbiota by 16S ribosomal ribonucleic acid gene sequencing.

177 2 domains of the large subunit (LSU) nuclear ribosomal RNA (nrRNA) gene and by morphological characte

178 e in ribosome biogenesis, functioning in pre-ribosomal RNA (pre-rRNA) processing as a component of th

179 RNA degradation procedure that minimizes pre-ribosomal RNA (pre-rRNA) transcripts.

180 Ribosomal RNA (rRNA) accounts for the majority of the RN

181 ite-specific endonucleolytic cleavage in 25S ribosomal RNA (rRNA) adjacent to the c loop of the expan

182 unit has been built de novo and includes 15S ribosomal RNA (rRNA) and 34 proteins, including 14 witho

183 tuberculosis (Mtb) possess species-specific ribosomal RNA (rRNA) expansion segments and ribosomal pr

184 ial ribosomal protein MRPS10 and reduced 12S ribosomal RNA (rRNA) expression, suggesting mitochondria

185 gal molecular diversity (small subunit (SSU) ribosomal RNA (rRNA) gene sequences) in field samples.

186 d-collected Helicoverpa zea larvae using 16S ribosomal RNA (rRNA) gene sequencing and matrix-assisted

187 The resulting accumulation of ribosomal RNA (rRNA) precursor-analyzed by RNA fluoresce

188 We examined the relationship between ribosomal RNA (rRNA) production and IGF-1-mediated myotu

189 een studied in detail, little is known about ribosomal RNA (rRNA) structural rearrangements that take

190 enesis and identified a role for this GEF in ribosomal RNA (rRNA) synthesis that is mediated by Rac1

191 tes with Grc3-Rat1-Rai1 to process precursor ribosomal RNA (rRNA), yet its mechanism of action remain

192 g, cleavage, and modification of nascent pre-ribosomal RNA (rRNA).

193 ogenome contained 13 protein coding genes, 2 ribosomal RNA and 22 transfer RNA genes, and a control r

194 N1-regulated genes, including those encoding ribosomal RNA and the cytokine IL1B.

195 nomic units were pyrosequenced targeting 16S ribosomal RNA and volatile organic compounds determined

196 The probe incorporated into the bacterial ribosomal RNA decoding site, fluorescently reports antib

197 complete nuclear transcriptome, including a ribosomal RNA degradation procedure that minimizes pre-r

198 to the most-likely IDs, (iii) comprehensive ribosomal RNA filtering for accurate mapping of exogenou

199 emistry to detect mucin 2, as well as by 16S ribosomal RNA fluorescence in situ hybridization, transc

200 n of fecal microbiota were determined by 16S ribosomal RNA gene amplicon sequencing, and metabolite p

201 ed by sequencing the V3/V4 region of the 16S ribosomal RNA gene and by hierarchical clustering.

202 By applying metabolomic and metagenomic (16S ribosomal RNA gene and whole-genome shotgun sequencing)

203 oughput sequencing after construction of 16S ribosomal RNA gene libraries.

204 xonomic units, enable bacterial and archaeal ribosomal RNA gene sequences to be followed across multi

205 16S ribosomal RNA gene sequencing detected diverse bacterial

206 Bacterial DNA was isolated, and the 16S ribosomal RNA gene was amplified and sequenced.

207 -cell diversity of the usually conserved 16S ribosomal RNA gene, we suggest that gene conversion occu

208 n, and infant stool by sequencing of the 16S ribosomal RNA gene.

209 hain reaction (PCR) assays targeting the 16S ribosomal RNA gene.

210 focused on the MPa adhesion gene and the 16S ribosomal RNA gene.

211 cox1-3, nad1-6, nad4L, atp6 and cob) and two ribosomal RNA genes (rrnL and rrnS), but the atp8 gene w

212 ng nested polymerase chain reaction (PCR) of ribosomal RNA genes and a novel assay that amplifies a c

213 Ribosomal RNA genes in sequenced DNA of natural ferns, t

214 sponding to active transposons, CRISPR loci, ribosomal RNA genes, rolling circle origins of replicati

215 cale features of ribosomes-such as why a few ribosomal RNA molecules dominate the mass and why the ri

216 modulation factor (PA3049), is required for ribosomal RNA preservation during prolonged nutrient sta

217 nd organism viability because of its role in ribosomal RNA processing and protein synthesis, which is

218 identified a 3' to 5' exoribonuclease, RRP6 (ribosomal RNA processing protein 6), as a CELF1-interact

219 ts derived from healthy individuals and that ribosomal RNA production increases with age, indicating

220 that host-derived RNAs, most prominently 5S ribosomal RNA pseudogene 141 (RNA5SP141), bound to RIG-I

221 h the hierarchical addition of proteins to a ribosomal RNA scaffold.

222 heral blood mononuclear cells as well as 16S ribosomal RNA sequencing data from bronchoalveolar lavag

223 House dust microbiome analysis using 16S ribosomal RNA sequencing identified 202 and 171 bacteria

224 Fecal samples were analyzed by 16s ribosomal RNA sequencing.

225 sition of the microbiota was analyzed by 16S ribosomal RNA sequencing.

226 icase DHX33, which is critically involved in ribosomal RNA synthesis and mRNA translation.

227 creases upstream binding factor recruitment, ribosomal RNA synthesis, ribonucleotide levels, and affe

228 y samples were collected and analyzed by 16S ribosomal RNA targeted pyrosequencing.

229 recognition of its two structurally distinct ribosomal RNA targets.

230 is derived from Salmonella 5'-leader of the ribosomal RNA transcript and has a 'stem' structure-cont

231 F13 1A is a nucleolar protein that represses ribosomal RNA transcription and attenuates protein synth

232 nities in fecal samples were profiled by 16S ribosomal RNA-based polymerase chain reaction-temporal t

233 cRNA expression from both simulated and real ribosomal RNA-depleted (rRNA-depleted) RNA-seq datasets.

234 -generation sequencing targeting 16S and 18S ribosomal RNA.

235 atalyse the site-specific 2-O-methylation of ribosomal RNA.

236 ablishes idiosyncratic interactions with the ribosomal RNA.

237 s that are peculiar to specific positions in ribosomal RNAs and that are stabilized by tertiary inter

238 ous studies have identified p90 subfamily of ribosomal S6 kinase (p90RSK) family kinases as key facto

239 leading to increased phosphorylation of p90-ribosomal S6 kinase (RSK) and a concomitant activation o

240 tracellular signal-regulated kinase 1/2, and ribosomal S6 kinase 1 signal transduction pathways and s

241 t extracellular signal-regulated kinase 1/2, ribosomal S6 kinase 1, or cAMP responsive element bindin

242 The p90 ribosomal S6 kinase family (RSK1-4) is a group of highly

243 inhibitor, GDC-0941, targeted the downstream ribosomal S6 kinase phosphorylation to significantly sup

244 echanism, unlike in macrophages in which p90 ribosomal S6 kinase was not required.

245 of mitogen-activated protein kinase kinase, ribosomal S6 kinase, and cyclin-dependent kinase 1/2 in

246 g p70 S6-kinase, glycogen synthase kinase-3, ribosomal S6 kinase, c-Jun, and cAMP response element bi

247 B cells was regulated by an ERK1/2- and p90 ribosomal S6 kinase-dependent mechanism, unlike in macro

248 ibition of the proteasome (by MG-132) or p90 ribosomal S6 kinases (by BI-D1870) is further increased

249 RSKs (p90 ribosomal S6 kinases) have emerged as central regulators

250 aled that the increase in phosphorylation of ribosomal S6 was mediated by BLT-1 in healthy subject ne

251 by phosphorylation of the signaling protein ribosomal S6.

252 al to that of the parent yet displays better ribosomal selectivity, predictive of an enhanced therape

253 ed for allo-HCT was profiled by means of 16S ribosomal sequencing of prospectively collected stool sa

254 roteins are part of a structure known as the ribosomal stalk and help orchestrate the elongation phas

255 of ZIKV-C prevented nucleolar localization, ribosomal stress and apoptosis.

256 capsid protein (ZIKV-C) was associated with ribosomal stress and apoptosis.

257 on were reduced, indicative of mitochondrial ribosomal stress and increased transforming growth facto

258 bosome biogenesis and function and result in ribosomal stress and p53 activation.

259 patients show defective rRNA processing and ribosomal stress features such as reduced proliferation,

260 neurons Zika virus (ZIKV) infection leads to ribosomal stress that is characterized by structural dis

261 (rRNA) expression, suggesting mitochondrial ribosomal stress.

262 Conversely, ribosomal structure and photosystem genes were immediate

263 rRNA) processing as a component of the small ribosomal subunit (SSU) processome.

264 nt the near-atomic structures of the Mtb 50S ribosomal subunit and the complete Mtb 70S ribosome, sol

265 the protein composition of various yeast 60S ribosomal subunit assembly intermediates has been studie

266 t proteins to organize RNA structure for 40S ribosomal subunit assembly.

267 s an RRM protein that is essential for large ribosomal subunit biogenesis.

268 ganizes the assembly of the eukaryotic small ribosomal subunit by coordinating the folding, cleavage,

269 Although ribosomal subunit dissociation and nascent peptide degra

270 The binding interface on the large ribosomal subunit is buried by the small subunit during

271 insufficiency of Mrpl40 (mitochondrial large ribosomal subunit protein 40) as a contributor to abnorm

272 serine/threonine residues in the human small ribosomal subunit protein, receptor for activated C kina

273 eIF4A modulates the conformation of the 40S ribosomal subunit to promote mRNA recruitment.

274 peptidyl-tRNA enters the P site of the small ribosomal subunit via reversible, swivel-like motions of

275 the nascent peptide exit tunnel of the large ribosomal subunit with comparable affinities, the bacter

276 elongation', 'translation factor activity', 'ribosomal subunit' and 'phosphorelay signal transduction

277 ory region located on the surface of the 60S ribosomal subunit.

278 complex (TC), which is recruited to the 40S ribosomal subunit.

279 in IIId(1) is crucial for recruiting the 40S ribosomal subunit.

280 t penetrates deep into the core of the large ribosomal subunit.

281 ropose that rRNAs not packaged into complete ribosomal subunits are polyadenylated by the poly(A) pol

282 ient peptide segments from the cores of both ribosomal subunits enhance RNA polymerase ribozyme (RPR)

283 neighboring proline residue resulting in 40S ribosomal subunits that were blocked from polysome forma

284 Upon joining of the large and small ribosomal subunits, a 100-nt long expansion segment of t

285 e proteins depends on interactions with both ribosomal subunits, some portion of 30S and 50S assembly

286 r the interactions between both of the small ribosomal subunits.

287 binds ribosomes and isolated large and small ribosomal subunits.

288 NA and nascent chain destruction and recycle ribosomal subunits.

289 is also present within the highly conserved ribosomal subunits.

290 ed drug candidate is described that inhibits ribosomal synthesis of PCSK9, a lipid regulator consider

291 ation on the 40S protein eS10 as the primary ribosomal target of ZNF598.

292 ed in critical binding interactions with the ribosomal target, is replaced by an apramycin-like dioxa

293 cts of mutations, C-terminal extensions, and ribosomal tethering on the structure and stability of th

294 Ribosomal translation factors are fundamental for protei

295 known for global effects on mRNA repair and ribosomal translation.

296 The ribosomal tunnel also provides a protected environment f

297 iation with this motif upon emergence at the ribosomal tunnel exit requires ribosome-associated compl

298 tween positively charged amino acids and the ribosomal tunnel.

299 ting distinct and overlapping regulatory 40S ribosomal ubiquitylation events.

300 to the formation of a new subclass of human ribosomal ultrafine anaphase bridges.