ライフサイエンスコーパス: ribosomal protein

1 hosphorylated 4E-binding protein 1, and p-S6 ribosomal protein.

2 gnaling molecules, JAK1, STAT5, MAPK and pS6 ribosomal protein.

3 ed selectively phosphorylation of Akt and S6 ribosomal protein.

4 omic data confirmed the normalization of the ribosomal proteins.

5 -expressed genes, which code for cytoplasmic ribosomal proteins.

6 e also saw effects on expression of multiple ribosomal proteins.

7 ction of telomerase components and other non-ribosomal proteins.

8 intact, except for reduced amounts of seven ribosomal proteins.

9 gger site-specific ubiquitination on several ribosomal proteins.

10 and is accompanied by decreased abundance of ribosomal proteins.

11 karyotic ribosomes are composed of rRNAs and ribosomal proteins.

12 ensity, which affected mostly mRNAs encoding ribosomal proteins.

13 mal proteins competes with production of non-ribosomal proteins.

14 d down-regulation of genes encoding rRNA and ribosomal proteins.

15 -dependent upregulation of mitochondrial 37S ribosomal protein 1/ATP-binding cassette subfamily C mem

16 no significant defect in the import of small ribosomal protein 16 in the absence of full-length Tic56

17 The largest number of genes mapped to ribosomal proteins, a signature hitherto not associated

18 We find that cells produce excess ribosomal proteins, amounting to a constant approximatel

19 ly constant the level of ribosomes producing ribosomal proteins, an important quantity for cell growt

20 symbionts, and specific lineages are missing ribosomal proteins and biogenesis factors considered uni

21 ed activation of E3 ligase MDM2 that targets ribosomal proteins and by sigmaA-mediated upregulation o

22 (GR)80 preferentially bound to mitochondrial ribosomal proteins and caused mitochondrial dysfunction.

23 tional defect in the accumulation of plastid ribosomal proteins and diminished expression of plastid

24 ociated with decreased expression of several ribosomal proteins and enhanced inhibition of protein sy

25 sm by incorporation of a particular class of ribosomal proteins and final cleavage of 18S-E pre-rRNA

26 Pathway analyses highlighted multiple ribosomal proteins and known limb patterning signaling p

27 Notably, translation of mRNAs for ribosomal proteins and mitochondrial respiration peaked

28 ntation together with decreased abundance of ribosomal proteins and nucleotide reductase NrdEF was ob

29 rocess that involves the ordered assembly of ribosomal proteins and numerous RNA structural rearrange

30 UBE2O recognized ribosomal proteins and other substrates directly, target

31 al decoding center to differentially remodel ribosomal proteins and rRNA.

32 iogenesis requires stoichiometric amounts of ribosomal proteins and rRNAs.

33 omoters of Pol II-transcribed genes encoding ribosomal proteins and snoRNAs.

34 e nuclear import of approximately 80 nascent ribosomal proteins and the elimination of excess amounts

35 sors, as well as the translation of specific ribosomal proteins and translation factors.

36 stimulated genes and decreased expression of ribosomal proteins and translation factors.

37 osine [m(7)G] cap of TOP mRNAs, which encode ribosomal proteins and translation factors.

38 bly chaperones recognize nascent unassembled ribosomal proteins and transport them together with kary

39 ups, including cytoplasmic and mitochondrial ribosomal proteins, and display cellular phenotypes cons

40 ude mtDNA replication factors, mitochondrial ribosomal proteins, and electron-transport chain subunit

41 e obtained by analysis of 16S rRNA genes and ribosomal proteins, and FFP- and core genome single nucl

42 d iPSS in the polycistronic operons encoding ribosomal proteins, and the majority upstream and proxim

43 nucleoli, and decreased expression of rRNA, ribosomal proteins, and the nucleolar protein fibrillari

44 rrect folding of rRNAs, incorporation of >50 ribosomal proteins, and their maturation.

45 ding genes, including the highly transcribed ribosomal protein- and glycolytic enzyme-encoding genes.

46 lation, emerging evidence suggests that some ribosomal proteins are also capable of performing tissue

47 Nearly half of ribosomal proteins are composed of a domain on the ribos

48 urbation studies indicate that overexpressed ribosomal proteins are degraded by the ubiquitin-proteas

49 es as growth rate decreases and these excess ribosomal proteins are employed when translation demands

50 Astrocyte ribosomal proteins are found adjacent to synapses in viv

51 Surprisingly, the host's ribosomal proteins are packaged in the virion.

52 We postulate that these ribosomal proteins are required for efficient translatio

53 The ribosomal proteins are themselves subjected to translati

54 Ribosomal proteins are translated in the cytoplasm and i

55 ble for import can maintain the stability of ribosomal proteins by neutralizing unfavorable positive

56 RV coordinately regulates the degradation of ribosomal proteins by p17-mediated activation of E3 liga

57 control that involves the ubiquitination of ribosomal proteins by the E3 ubiquitin ligase Hel2/RQT1.

58 eemingly ubiquitously expressed and required ribosomal proteins can have distinct functions in cell a

59 Ribosomal proteins cannot be overproduced in Saccharomyc

60 Mutations in ribosomal proteins cause bone marrow failure syndromes a

61 logical culture, nucleic acid amplification, ribosomal protein characterization, and genome sequencin

62 re notably stronger for the highly expressed ribosomal protein coding transcripts.

63 osomes drive cell growth, but translation of ribosomal proteins competes with production of non-ribos

64 A new study shows that splitting ribosomal protein content into many small, similarly siz

65 RNA molecules dominate the mass and why the ribosomal protein content is divided into 55-80 small, s

66 he complete set of 79 eukaryotic cytoplasmic ribosomal proteins (cRPs) for a single copepod species.

67 on and metabolism, as well as those encoding ribosomal proteins, DNA and histone-modifying enzymes an

68 ging principles to understand how eukaryotic ribosomal proteins drive ribosome assembly in vivo.

69 he SRT of IE62 interacted with the nucleolar-ribosomal protein EAP, which resulted in the formation o

70 The main component of this bridge is ribosomal protein eL19 that is composed of an N-terminal

71 gulates nutrient-dependent downregulation of ribosomal protein encoding RNAs, leading to the redistri

72 cation of CD4(+) T cell responses to defined ribosomal protein epitopes expands the range of antigeni

73 omal subunits with a fluorescent SNAP-tag at ribosomal protein eS25 (RPS25).

74 at ES7 is a binding hub for a variety of non-ribosomal proteins essential to ribosomal function in eu

75 Accordingly, approximately 25% of ribosomal proteins expressed in rapidly growing cells do

76 Although ribosomal proteins facilitate the ribosome's core functi

77 ed us to identify previously unknown NLSs in ribosomal proteins from humans, and suggests that, apart

78 oning the assembly site, and dissociation of ribosomal proteins from karyopherins.

79 ignature, which is associated with defective ribosomal protein function and linked to the erythroid l

80 sights into the mechanism of a mitochondrial ribosomal protein function in cell death.

81 omembrane trafficking pathways downstream of ribosomal protein function.

82 Here, we discuss ribosomal protein functions in health and disease, focus

83 em that coordinates ribosomal RNA (rRNA) and ribosomal protein gene (RPG) transcription has been desc

84 significant insights into the regulation of ribosomal protein gene expression and, hence, ribosome b

85 imals have altered ribosomal RNA biogenesis, ribosomal protein gene expression, and elevated levels o

86 s at least in part due to down-regulation of ribosomal protein gene expression, leading to the redist

87 d to optimize the efficiency and accuracy of ribosomal protein gene expression, while allowing flexib

88 avior is associated with intron retention in ribosomal protein gene transcripts, a decrease in splici

89 Ribosomal protein genes (RPGs) are important house-keepi

90 The 137 ribosomal protein genes (RPGs) of Saccharomyces provide

91 f many genes and is particularly enriched at ribosomal protein genes and in the promoter regions of r

92 RNA-seq analysis confirmed that introns in ribosomal protein genes are more highly expressed when t

93 We identified ribosomal protein genes as possessing a conflicting sign

94 role in targeting TFIID to the promoters of ribosomal protein genes for transcriptional initiation i

95 -independent form of TBP to the promoters of ribosomal protein genes for transcriptional initiation.

96 t of cells appears to decouple expression of ribosomal protein genes from the environmental stress re

97 Mutations in ribosomal protein genes have been identified in approxim

98 ing corrFISH, we quantified highly expressed ribosomal protein genes in single cultured cells and mou

99 of adenosine triphosphate (ATP) synthase and ribosomal protein genes were depleted in the uninfected

100 bundant class of intron-containing RNAs (the ribosomal protein genes) to Mer1-regulated transcripts.

101 dates identified in this search included two ribosomal protein genes, RPL35a and RPL23, and ferredoxi

102 w that NuA4 is recruited to the promoters of ribosomal protein genes, such as RPS5, RPL2B, and RPS11B

103 own whether, like sense transcription of the ribosomal protein genes, TAF-dependent antisense transcr

104 tein (TBP)-associated factor (TAF)-dependent ribosomal protein genes.

105 -independent form of TBP to the promoters of ribosomal protein genes.

106 al electron transport complex components and ribosomal protein genes.

107 tood how NuA4 regulates the transcription of ribosomal protein genes.

108 p of human disorders most commonly caused by ribosomal protein haploinsufficiency or defects in ribos

109 it phosphorylation of ERK, histone H3 and S6 ribosomal protein in striatal slices.

110 s regulates the combinatorial composition of ribosomal proteins in developing neocortex, which we ter

111 or, and need to better understand, roles for ribosomal proteins in human development and disease has

112 e led to accumulation of multiple endogenous ribosomal proteins in insoluble aggregates, consistent w

113 atically acquired mutations and deletions in ribosomal proteins in T-cell acute lymphoblastic leukemi

114 Among 79 ribosomal proteins in yeast, only a few are identified w

115 h evolutionarily ancient functions (e.g. the ribosomal proteins), in contrast to those with more rece

116 er acetylation occupancy and lower levels of ribosomal proteins, including those involved in ribosome

117 ow that MageB2 counteracts E2F inhibition by ribosomal proteins independently of Mdm2 expression.

118 ncing of Rps19, but not several other tested ribosomal proteins, indicating distinct cellular respons

119 teostatic response by reducing mitochondrial ribosomal proteins, inhibiting mitochondrial translation

120 ) demonstrate how the production of rRNA and ribosomal proteins is coordinated through a two-step res

121 how that translation of transcripts encoding ribosomal proteins is regulated during the differentiati

122 cularly, the loss reduces transcription of a ribosomal protein L10 (Rpl10)-like gene and the cell cyc

123 nuclear-specific association of PRAS40 with ribosomal protein L11 (RPL11).

124 d identified, namely enolase, cyclophilin-A, ribosomal protein L13 and actin-1.

125 ur snoRNAs encoded within the introns of the ribosomal protein L13a (Rpl13a) locus in a mouse model.

126 mic distribution of box C/D snoRNAs from the ribosomal protein L13a (Rpl13a) locus.

127 nthesis, class S (PIGS); prominin 1 (PROM1); ribosomal protein L13A (RPL13A); and microphthalmia-asso

128 NA and interacting with arginine residues of ribosomal protein L16.

129 Binding of EBER1 to ribosomal protein L22 (RPL22) was confirmed.

130 despite the ubiquitous expression of the RP ribosomal protein L22 (Rpl22), germline ablation of Rpl2

131 conventional organelles, colocalize with the ribosomal protein L22, and cluster the WNK signaling pat

132 h the cap structure and interacting with the ribosomal protein L23a.

133 lation of microRNA-27a and downregulation of ribosomal protein L26 (RPL26).

134 Ribosomal protein L27 is a component of the eubacterial

135 (ii) lesions in rpmA and rpmE, which encode ribosomal proteins L27 and L31, respectively; (iii) dele

136 (Ebola virus C20 peptide and the 70-residue ribosomal protein L31).

137 We report the crystal structure of ribosomal protein L4 (RpL4) bound to its dedicated assem

138 rogenesis promotes a change in the levels of Ribosomal protein L7 in polysomes, thereby regulating ne

139 sly folding protein domains derived from the ribosomal protein, L9.

140 Conversely, ribosomal protein large P0 (Rplp0), non-POU domain conta

141 iptomic analyses show progressive changes in ribosomal protein levels and mitochondrial function as e

142 ities were also correlated with the cellular ribosomal protein levels, thereby suggesting that mRNA p

143 This tsRNA binds at least two ribosomal protein mRNAs (RPS28 and RPS15) to enhance the

144 elevates the expression of a large subset of ribosomal protein mRNAs.

145 y the mitochondrial genome and mitochondrial ribosomal proteins (MRPs) that are encoded by nuclear ge

146 ppressed the expression of the mitochondrial ribosomal protein MRPS10 and reduced 12S ribosomal RNA (

147 tivity of specific cells and tissue types to ribosomal protein mutations.

148 xpression linkages with BCR-ABL pathways and ribosomal protein networks in CML than normal.

149 ncreases in families of transcripts encoding ribosomal proteins, non-structural factors affecting rib

150 All are missing a ribosomal protein often absent in symbionts, and specifi

151 ely congenital diseases linked to defects in ribosomal proteins or biogenesis factors.

152 istance converge on translation by targeting ribosomal proteins or initiation factors, but whether th

153 ation of this QC mechanism in the absence of ribosomal protein overexpression.

154 ls and immunoreactivity of phosphorylated S6 ribosomal protein (p-s6P) is significantly increased in

155 In addition to downregulating ribosomal proteins, p17 reduces mTORC2 assembly and disr

156 mposed of 9S and 12S rRNAs, eubacterial-type ribosomal proteins, polypeptides lacking discernible mot

157 proteins in obesity, and a normalization of ribosomal proteins post-RYGB.

158 clinical aggressiveness involving a mutated ribosomal protein, potentially representing an early gen

159 LARP4 is a posttranscriptional regulator of ribosomal protein production in mammalian cells and sugg

160 cluding multiple aminoacyl tRNA synthetases, ribosomal proteins, protein chaperones, and the Clp syst

161 ocesses: RNA processing; gene transcription; ribosomal proteins; protein degradation; and metabolism

162 o refer to this pathway as ERISQ, for excess ribosomal protein quality control.

163 involving temporally and spatially regulated ribosomal protein (r-protein) binding and ribosomal RNA

164 Spatial clustering of ribosomal proteins (r-proteins) through tertiary interac

165 that the ZNF598 ubiquitin ligase and the 40S ribosomal protein RACK1 help to resolve poly(A)-induced

166 s mediated by an interaction with a specific ribosomal protein, RACK1, and that an increase in cytopl

167 y ZNF598 triggered ubiquitination of several ribosomal proteins, requiring the E2 ubiquitin ligase UB

168 duration of feast and the allocation of the ribosomal protein reserve to maximize the overall gain i

169 Ribosomal protein (RP) expression in higher eukaryotes i

170 Ribosomal protein (RP) gene mutations, mostly associated

171 zygous chromosomal deletions, we reveal that ribosomal protein (RP) genes are the most significant ha

172 Ribosomal protein (RP) genes must be coordinately expres

173 most often due to heterozygous mutations in ribosomal protein (RP) genes that lead to defects in rib

174 have heterozygous mutations or deletions in ribosomal protein (RP) genes while <1% of patients with

175 Glucose signalling through PKA stabilized ribosomal protein (RP) mRNAs whereas glucose starvation

176 As with concomitant stabilization, including ribosomal protein (RP) mRNAs.

177 Overproduced yeast ribosomal protein (RP) Rpl26 fails to assemble into ribo

178 As recent studies have shown that loss of ribosomal protein (RP) S6 kinase 1 (S6K1) increases syst

179 The ribosomal protein (RP)-HDM2-p53 pathway has been shown t

180 To determine the contribution of the ribosomal protein (RP)-murine double minute 2 (MDM2)-p53

181 It requires coordinated production of ribosomal proteins (RP) and ribosomal RNA (rRNA), includ

182 Although ribosomal proteins (RP) are thought to primarily facilit

183 In lymphoma, both p19ARF and ribosomal proteins RPL11 and RPL5 respond to c-MYC activ

184 that germline ablation of the gene encoding ribosomal protein Rpl22 causes a selective and p53-depen

185 We reported previously that the ribosomal protein Rpl22 is a tumor suppressor in T-cell

186 Furthermore, our data suggest that ribosomal protein RPL23A interacts with NGP-1 and abolis

187 munoprecipitates with RNA polymerase I, with ribosomal proteins RPL26 and RPL24, and with components

188 Among these genes ribosomal protein RPL35A, putative RNA helicase DDX24, a

189 ilitate ribosome recruitment and require the ribosomal protein RPL38 for their activity.

190 ch other and both proteins interact with the ribosomal protein Rpl43 (L43e).

191 efaciens (AtMETTL20), namely ETFbeta and the ribosomal protein RpL7/L12.

192 he ribosome through interaction with another ribosomal protein, RPLP0, to form a structure termed the

193 In these screens, we identified ribosomal proteins RPLP1 and RPLP2 (RPLP1/2) to be among

194 , ribosomal RNA (rRNA) helices H89, H91, and ribosomal proteins (rProtein) uL16-these structures reve

195 ribosomal RNA (rRNA) expansion segments and ribosomal proteins (rProtein).

196 Interactions between ribosomal proteins (rproteins) and ribosomal RNA (rRNA)

197 folding and local autonomy of assembly with ribosomal proteins (rProteins), and that the rProtein an

198 s specific protein synthesis factors such as ribosomal protein RPS-1 and translation initiation facto

199 ribosome heterogeneity at the level of core ribosomal proteins (RPs) exists and enables ribosomes to

200 erarchical incorporation of approximately 80 ribosomal proteins (RPs) into the ribosomal RNA core.

201 ation in eukaryotes created paralog pairs of ribosomal proteins (RPs) that show high sequence similar

202 The process through which ribosomal proteins (RPs) transduce nucleolar stress sign

203 Yeast ribosomal protein Rps3/uS3 resides in the mRNA entry cha

204 The ribosomal protein RPSA interacts with ZNF804A and rescue

205 binds within the carboxy-terminal domain of ribosomal protein S1 (RpsA) and inhibits trans-translati

206 otein A, stringent starvation protein A, 30S ribosomal protein s1 and 60 kDa chaperonin) were identif

207 Ribosomal protein S1 forms a wall of the tunnel between

208 with mutations of genes for the chloroplast ribosomal proteins S1 (PRPS1) and L11.

209 hisms in fd (ferredoxin), arps10 (apicoplast ribosomal protein S10), mdr2 (multidrug resistance prote

210 t identified NBP35 and DRE2 (Derepressed for Ribosomal protein S14 Expression).

211 nd many RNAs that interact specifically with ribosomal protein S15 from Geobacillus kaustophilus with

212 Ribosomal protein S15 is autogenously regulated via an R

213 that interact with Geobacillus kaustophilus ribosomal protein S15.

214 Ribosomal protein s15a (RPS15A) plays a promotive role i

215 rt novel immunosuppressive properties of the ribosomal protein S19 (RPS19), which is upregulated in h

216 e proteins, including the putatively ancient ribosomal protein S20 (RPS20), which only becomes struct

217 d in studying the interaction of RECQL4 with ribosomal protein S3 (RPS3) because previous studies hav

218 SH-mediated activation of the mTOR complex 1/ribosomal protein S6 (mTORC1/RPS6) pathway as well as th

219 overexpression increased phosphorylation of ribosomal protein S6 (p-rpS6) in SNpc neurons, a readout

220 sphate feeding, generate less phosphorylated ribosomal protein S6 (P-S6) than the WT.

221 Here, the signal from phosphorylated ribosomal protein S6 (P-S6) was defined as a surrogate m

222 rs prolonged signaling through activation of ribosomal protein S6 (RPS6) and the upstream kinase 90-k

223 1 (4E-BP1) and increased phosphorylation of ribosomal protein S6 (rpS6) in activated renal tubules.

224 was measured by increased phosphorylation of ribosomal protein S6 (rpS6), a downstream target of the

225 6 kinase (p70S6K) and its downstream target, ribosomal protein S6 (S6RP), was impaired at a critical

226 -LTD, through a mechanism involving mTOR and ribosomal protein S6 activation.

227 ll internal antigen-1 with eIF3b, eIF4E, and ribosomal protein S6 and studied eIF2 and eIF4F complex.

228 ng MOR161-2 in vivo using the phosphorylated ribosomal protein S6 as a marker.

229 was associated with decreased phosphorylated ribosomal protein S6 immunoreactivity.

230 IL-7 treatment increased levels of phospho-ribosomal protein S6 in HIV-specific CD8 T cells, sugges

231 g behavior, and increased phosphorylation of ribosomal protein S6 in the medial prefrontal cortex (mP

232 In the absence of ERK2, activation of the ribosomal protein S6 kinase (p70S6K) and its downstream

233 Ribosomal protein S6 kinase (RPS6KA3 or RSK2) was the mo

234 mTORC1 regulates p70 ribosomal protein S6 kinase 1 (S6K1) and eukaryotic init

235 rget of rapamycin complex 1 (mTORC1) and p70 ribosomal protein S6 kinase 1 (S6K1) axis.

236 iation factor-binding protein 1 (4E-BP1) and ribosomal protein S6 kinase 1 (S6K1).

237 of mammalian target of rapamycin complex 1, ribosomal protein S6 kinase 1, and eukaryotic translatio

238 In this study, we evaluated p70 ribosomal protein S6 Kinase 2 (S6K2), a downstream effec

239 ivated protein kinase (AMPK) and upstream of ribosomal protein S6 kinase and mTOR complex 1 (TORC1),

240 gnaling in the tumor, as measured by reduced ribosomal protein S6 kinase phosphorylation.

241 ponents of the mammalian target of rapamycin/ribosomal protein S6 kinase, 70 kDa, pathway and thereby

242 the oncogenic mammalian target of rapamycin/ribosomal protein S6 kinase, 70 kDa, pathway, and the im

243 Ribosomal protein S6 kinase, 90 kDa, polypeptide 1 (RSK1

244 lular signal-regulated kinase) and S6K-RPS6 (ribosomal protein S6 kinase-ribosomal protein S6) axes.

245 Immunohistochemistry showed patches of ribosomal protein S6 positivity in a similar distributio

246 es expressed higher levels of phosphorylated ribosomal protein S6 than paired fibroblasts from normal

247 -E1A12 increased phosphorylation of AKT1 and ribosomal protein S6 through independent mechanisms in d

248 ls, and decreased phosphorylation of phospho-ribosomal protein S6 was also observed, a finding sugges

249 e) and S6K-RPS6 (ribosomal protein S6 kinase-ribosomal protein S6) axes.

250 nstrate that both S18 proteins interact with ribosomal protein S6, a committed step in ribosome bioge

251 bundances of insulin receptor, GLUT4, AS160, ribosomal protein S6, and FOXO1.

252 B (trkB), namely, phosphorylation of Akt and ribosomal protein S6, in SN neurons.

253 Phosphorylation of ribosomal protein S6, typically a downstream target of m

254 ition of the latter process by knockdowns of ribosomal proteins S6, S14, or L4 reduced ribosome conte

255 mutation in the gene encoding mitochondrial ribosomal protein S7 (MRPS7), a c.550A>G transition that

256 The genes encoding for ribosomal proteins show distinctive features at both end

257 Nucleolar and ribosomal proteins showed short half-lives, whereas mito

258 ozygous deletion of RPS14, which encodes the ribosomal protein small subunit 14.

259 NA translation complexes (polysomes) contain ribosomal protein subsets that undergo dynamic spatiotem

260 cytb) and the azithromycin-binding region of ribosomal protein subunit L4 (rpl4).

261 s of chloroplast-localized proteins, such as ribosomal proteins, subunits of the RNA polymerase, and

262 lision in vivo resulted in ubiquitination of ribosomal proteins, suggesting that collision is sensed

263 olecular dynamics simulations show that each ribosomal protein switches the 16S conformation and damp

264 ional regulation is a potential mechanism of ribosomal protein synthesis and stoichiometry.

265 f Rv1738 is to contribute to the shutdown of ribosomal protein synthesis during the onset of nonrepli

266 urthermore, both anisomycin, an inhibitor of ribosomal protein synthesis, and rapamycin, an inhibitor

267 nal fashion with a phase opposite to that of ribosomal protein synthesis.

268 oupling of cognate amino acids and tRNAs for ribosomal protein synthesis.

269 RPS3 is a small ribosomal protein that also has extraribosomal functions

270 DAP3 is a mitochondrial ribosomal protein that involves in apoptosis, but its bi

271 Mutations in ribosomal proteins that affect mostly late steps lead to

272 We identified two specific ribosomal proteins that are strictly required for flaviv

273 In nonreticulocytes, ribosomal proteins that did not engage nuclear import fa

274 Our studies reveal that ribosomal proteins that fail to assemble into ribosomes

275 osomes involves the hierarchical addition of ribosomal proteins that progressively stabilize the fold

276 n PI3K mutant cancer cell lines converged on ribosomal protein translation and proteasomal protein de

277 nally stalled ribosomal fractions identified ribosomal proteins, translation factors and RNA-binding

278 NA complexes in cells and identified several ribosomal proteins, translation factors, and mRNAs.

279 PR peptide, including mRNA-binding proteins, ribosomal proteins, translation initiation factors and t

280 inal ribosome-binding domain (RBD) mainly to ribosomal protein uL23 at the tunnel exit on the large r

281 W255C mutation of the universally conserved ribosomal protein uL3 has diverse effects on ribosome fu

282 Globally, our data demonstrate that ribosomal protein uL3 is structurally essential to ensur

283 k showed that ribosomes lacking the loops of ribosomal proteins uL4 or uL22 are still capable of ente

284 We also identified ribosomal proteins under relaxed or neutral selection.

285 Eukaryotic ribosomal proteins, unlike their bacterial homologues, p

286 ere we report that ubiquitination of the 40S ribosomal protein uS10 by the E3 ubiquitin ligase Hel2 (

287 le molecule FRET to show how combinations of ribosomal proteins uS4, uS17 and bS20 in the 16S 5' doma

288 mall nucleolar RNAs and nuclear dispersal of ribosomal proteins, was the likely cause of the prolifer

289 that encode translation machinery, including ribosomal proteins, was upregulated during the T cell cl

290 dition, elevated levels of phosphorylated S6 ribosomal protein were identified in both neurons and as

291 ller dendritic trees were also observed when ribosomal proteins were depleted from neurons with estab

292 Numerous ribosomal proteins were identified, confirming the work

293 Proteomic analysis showed that ribosomal proteins were significantly downregulated wher

294 he majority of essential proteins, including ribosomal proteins, were downregulated upon exposure to

295 rate secondary structures and associate with ribosomal proteins, whereas nascent mRNAs are translated

296 netic system to starve cells of an essential ribosomal protein, which results in the accumulation of

297 the alternative RpmEB(L31*) and RpmGC(L33*) ribosomal proteins, which mobilize zinc from the ribosom

298 s genome encodes five putative 'alternative' ribosomal proteins whose expression is repressed at high

299 e through the addition of eukaryote-specific ribosomal proteins whose individual effects on ribosome

300 ransferase center, and stable association of ribosomal proteins with rRNA surrounding the polypeptide