ライフサイエンスコーパス: ribosomal subunit

1 nd is required for the assembly of the small ribosomal subunit.

2 large, multiprotein eIF3 complex to the 40S ribosomal subunit.

3 the decoding center of the A site of the 40S ribosomal subunit.

4 RPS19, which encodes a component of the 40S ribosomal subunit.

5 binding interface that clashes with the 40S ribosomal subunit.

6 rt fully into the P decoding site on the 40S ribosomal subunit.

7 RNA mapped the AMI binding site to the small ribosomal subunit.

8 RNA codon present in the A site of the small ribosomal subunit.

9 of the nuclear export adapter from the large ribosomal subunit.

10 TS2 rRNA processing and synthesis of the 60S ribosomal subunit.

11 complex (TC), which is recruited to the 40S ribosomal subunit.

12 an in vivo assembly landscape for the larger ribosomal subunit.

13 target site on the Thermus thermophilus 30S ribosomal subunit.

14 makes up the major mass and shape of the 60S ribosomal subunit.

15 ough an exit tunnel that traverses the large ribosomal subunit.

16 in a quality control complex with the large ribosomal subunit.

17 e P-site tRNA toward the A site of the large ribosomal subunit.

18 ibosome entry site (IRES) to recruit the 40S ribosomal subunit.

19 575 of rRNA in the P-site of the small (40S) ribosomal subunit.

20 in IIId(1) is crucial for recruiting the 40S ribosomal subunit.

21 es 43 and 95, and protein L11 within the 50S ribosomal subunit.

22 stimulated by its association with the 30 S ribosomal subunit.

23 movement of domain II of RRF towards the 30S ribosomal subunit.

24 and delivers the initiator tRNA to the small ribosomal subunit.

25 quired for assembly of the 30 S but not 54 S ribosomal subunit.

26 eH, has been linked to assembly of the small ribosomal subunit.

27 ructure of KsgA bound to a nonmethylated 30S ribosomal subunit.

28 ory region located on the surface of the 60S ribosomal subunit.

29 ribosome includes that of the isolated small ribosomal subunit.

30 PS15, a gene encoding a component of the 40S ribosomal subunit.

31 conserved role in the maturation of the 60S ribosomal subunit.

32 appears to be an essential core of the small ribosomal subunit.

33 protein uL23 at the tunnel exit on the large ribosomal subunit.

34 and the start codon in the P site of the 30S ribosomal subunit.

35 to the aminoacyl-tRNA site on the small 30S ribosomal subunit.

36 ructure around and within the developing 40S ribosomal subunit.

37 the peptidyltransferase center of the large ribosomal subunit.

38 rearrangements of the head domain in the 30S ribosomal subunit.

39 e conditions, BipA associates with the small ribosomal subunit.

40 t penetrates deep into the core of the large ribosomal subunit.

41 ng of eIF4G and the recruitment of the small ribosomal subunit.

42 tivity and the dissociation and recycling of ribosomal subunits.

43 binding specificity from ribosomes to small ribosomal subunits.

44 r the interactions between both of the small ribosomal subunits.

45 mRNA associating with polysomes versus free ribosomal subunits.

46 as components of precursors to 60S (pre-60S) ribosomal subunits.

47 eins to the RNAs forming the small and large ribosomal subunits.

48 yield the 18S ribosomal RNA component of 40S ribosomal subunits.

49 uses the aggregation of both small and large ribosomal subunits.

50 binds ribosomes and isolated large and small ribosomal subunits.

51 interdependence of the biogenesis of the two ribosomal subunits.

52 tructure that binds to 80S ribosomes and 60S ribosomal subunits.

53 ture of the RQC complex bound to stalled 60S ribosomal subunits.

54 s the rRNA components of the large and small ribosomal subunits.

55 NA and nascent chain destruction and recycle ribosomal subunits.

56 r with Ltn1 and the AAA-ATPase Cdc48, to 60S ribosomal subunits.

57 and maturation steps for construction of 60S ribosomal subunits.

58 three reactions but also re-associated yeast ribosomal subunits.

59 is also present within the highly conserved ribosomal subunits.

60 iting the association of the small and large ribosomal subunits.

61 the nucleus where Rps3 is assembled into pre-ribosomal subunits.

62 tion complex (PoTC) into mRNA, tRNA, and two ribosomal subunits.

63 f-mers and a moderate reduction in free 60 S ribosomal subunits.

64 mplex (TC), promoting its recruitment to 40S ribosomal subunits.

65 esulting in a reduction in the number of 40S ribosomal subunits.

66 al step during cytoplasmic maturation of 40S ribosomal subunits.

67 al structures of EF-G bound and EF-G unbound ribosomal subunits.

68 c factors required for the maturation of 60S ribosomal subunits.

69 we demonstrate the engineering of the small-ribosomal subunit (16S) RNA of Mycoplasma mycoides, by c

70 Methylation of the bacterial small ribosomal subunit (16S) rRNA on the N1 position of A1408

71 inal processing step to produce mature small ribosomal subunit 18S rRNA.

72 s of ribosome biogenesis in mammals, the two ribosomal subunits 40S and 60S are produced via splittin

73 somal Entry Site (CrPV-IRES) binds the small ribosomal subunit (40S) and the translocation intermedia

74 ociation factor eIF6 from the surface of the ribosomal subunit 60S.

75 presence of expansion segments in the large ribosomal subunit (60S) of Trypanosoma brucei.

76 nformation compatible with binding the large ribosomal subunit (60S).

77 Upon joining of the large and small ribosomal subunits, a 100-nt long expansion segment of t

78 noncoding ribosome, proto-mRNA and the small ribosomal subunit acted as cofactors, positioning the ac

79 change the folding or dynamics of the large ribosomal subunit, altering the rate of GTP hydrolysis a

80 factors (eIFs) in conjunction with the 40 S ribosomal subunit and (initiator) tRNA(i).

81 etween the Cy3-labeled L1 stalk of the large ribosomal subunit and a Cy5-labeled tRNA(Lys) in the rib

82 or L9), an essential component of the large ribosomal subunit and a putative tumor suppressor, was i

83 site (IRES) that can autonomously bind a 40S ribosomal subunit and accurately position it at the init

84 lants, besides being a component of the 40 S ribosomal subunit and acting as a target of TOR.

85 RPS29 is a component of the small 40S ribosomal subunit and essential for rRNA processing and

86 of EF-G moves toward the A site of the small ribosomal subunit and facilitates the movement of peptid

87 nce that this isolated domain binds the 50 S ribosomal subunit and hydrolyzes GTP.

88 estration of the early assembly of the large ribosomal subunit and in faithful protein production.

89 structural protein 1 (nsp1) binds to the 40S ribosomal subunit and inhibits translation, and it also

90 s LTO1; required for biogenesis of the large ribosomal subunit and initiation of translation in oxyge

91 which encodes a component (S20) of the small ribosomal subunit and is a new colon cancer predispositi

92 e A/U-tail enables mRNA binding to the small ribosomal subunit and is essential for translation.

93 and most variable ES of the eukaryotic large ribosomal subunit and is located at the surface of the r

94 a decrease of both its affinity for the 30 S ribosomal subunit and its GTPase activity, whereas a pho

95 n the three-dimensional structure of the 30S ribosomal subunit and probably act directly by compensat

96 tablishes how Ltn1 associates with the large ribosomal subunit and properly positions its E3-catalyti

97 2.5-A structure of the Trypanosoma cruzi 60S ribosomal subunit and propose a model for the stepwise a

98 nd initiator transfer RNA bound to the small ribosomal subunit and provide insights into the details

99 the closed and open conformations of the 30S ribosomal subunit and requires disruption of the interfa

100 vious in vitro assembly studies of the small ribosomal subunit and six 50S assembly groups that clear

101 nces tRNA binding to the P site of the large ribosomal subunit and slows down spontaneous intersubuni

102 nt the near-atomic structures of the Mtb 50S ribosomal subunit and the complete Mtb 70S ribosome, sol

103 M mediates an rRNA modification in the small ribosomal subunit and thus plays a role analogous to Ksg

104 ng that AROS selectively associates with 40S ribosomal subunits and also with polysomes.

105 NA processing resulted in an accumulation of ribosomal subunits and caused a significant delay in rib

106 ting with the 70S ribosome, may also bind to ribosomal subunits and form TF-polypeptide complexes tha

107 assembled at a very late stage into pre-60 S ribosomal subunits and that its incorporation into 60 S

108 gnificant role in the binding of Ltn1 to 60S ribosomal subunits and that NTD mutations causing defect

109 and Rlp24 release from cytoplasmic pre-60 S ribosomal subunits and their inefficient recycling back

110 elongation', 'translation factor activity', 'ribosomal subunit' and 'phosphorelay signal transduction

111 rRNA degradation, particularly in the large ribosomal subunit, and accumulate rRNA fragments after r

112 A-binding subunit of the small mitochondrial ribosomal subunit, and is required for the assembly of t

113 ates with translation-initiating factors and ribosomal subunits, and in vitro binding assays revealed

114 astid ribosomes, a specific depletion in 30S ribosomal subunits, and reduced activity of plastid prot

115 directly tracked the CrPV IRES, 40S and 60S ribosomal subunits, and tRNA using single-molecule fluor

116 nce dedicated assembly factors keep immature ribosomal subunits apart and prevent them from translati

117 e small (e.g., RPS19) or large (e.g., RPL11) ribosomal subunit are found in more than half of these p

118 pathways for Met-tRNA(i) delivery to the 40S ribosomal subunit are identified, but which one predomin

119 ce only occurs when both ppGpp and the small ribosomal subunit are present.

120 chromosomal DNA segregate, while 30S and 50S ribosomal subunits are able to penetrate the nucleoids.

121 te that structural domains of eukaryotic 60S ribosomal subunits are formed in a hierarchical fashion.

122 adopts a distinct conformation in which the ribosomal subunits are in a semirotated orientation and

123 However, this mechanism requires that free ribosomal subunits are not excluded from the nucleoid.

124 ropose that rRNAs not packaged into complete ribosomal subunits are polyadenylated by the poly(A) pol

125 o the nucleus and correct incorporation into ribosomal subunits are prerequisites for optimal growth

126 ngle-molecule methods, fluorescently labeled ribosomal subunits are required.

127 Initial recruitment of the small ribosomal subunit as well as two translocation steps bef

128 w that this protein interacts with the large ribosomal subunit as well as with a series of non-riboso

129 The small ribosomal subunit assembles cotranscriptionally on the n

130 tated iPSCs exhibited defects in 40S (small) ribosomal subunit assembly and production of 18S ribosom

131 assembly factors during the final stages of ribosomal subunit assembly and visualize structural feat

132 Ribosomal subunit assembly in the nucleolus is dependent

133 mature translation initiation on small (40S) ribosomal subunit assembly intermediates by blocking lig

134 the protein composition of various yeast 60S ribosomal subunit assembly intermediates has been studie

135 utated iPSCs exhibited defective 60S (large) ribosomal subunit assembly, accumulation of 12S pre-rRNA

136 t proteins to organize RNA structure for 40S ribosomal subunit assembly.

137 eukaryotic translation initiation, the small ribosomal subunit, assisted by initiation factors, locat

138 In eukaryotes, the large ribosomal subunit-associated quality control complex (RQ

139 Knockdown of eIF6 expression improved ribosomal subunit association but did not correct the he

140 d 43 ms and have determined 3D structures of ribosomal subunit association intermediates.

141 l translation initiation factor IF2 promotes ribosomal subunit association, recruitment, and binding

142 rRNA cleavage, MazF-mt6 destabilized 50S-30S ribosomal subunit association.

143 e rapid accumulation of immature 30S and 50S ribosomal subunits at 15 degrees C.

144 iciency of late steps in biogenesis of large ribosomal subunits at low temperatures, presumably while

145 The drug binds to both small and large ribosomal subunits at nine independent sites.

146 h the data pointing to an essential role for ribosomal subunits beyond translation.

147 ate in their maturation, nascent small (40S) ribosomal subunits bind 60S subunits to produce 80S-like

148 st a model whereby posttermination ribosomes/ribosomal subunits bind to the kl-TSS and are delivered

149 the eIF3c RNA-binding motif also reduce 40S ribosomal subunit binding to eIF3, and inhibit eIF5B-dep

150 ation of sdiA by directly competing with 30S ribosomal subunit binding.

151 nslation initiation in eukaryotes, the small ribosomal subunit binds messenger RNA at the 5' end and

152 According to the canonical mechanism, 40S ribosomal subunit binds to the 5'-end of messenger RNA (

153 Nop9 is a conserved small ribosomal subunit biogenesis factor, essential in yeast.

154 s an RRM protein that is essential for large ribosomal subunit biogenesis.

155 ases (Rio1, Rio2 and Rio3) function in small ribosomal subunit biogenesis.

156 ene and in vivo depletion of L40 impair 60 S ribosomal subunit biogenesis.

157 diffraction) and Thermus thermophilus small ribosomal subunit bound to the antibiotic paromomycin at

158 ganizes the assembly of the eukaryotic small ribosomal subunit by coordinating the folding, cleavage,

159 e dimethylation of a nucleotide in the large ribosomal subunit by erythromycin resistance methyltrans

160 The eukaryotic small ribosomal subunit carries only four ribosomal (r) RNA me

161 oli cells to determine the fractions of free ribosomal subunits, classify individual subunits as free

162 bundances of modified residues in incomplete ribosomal subunits compared to a mature (15)N-labeled rR

163 ys, shikimate derivative dependent pathways, ribosomal subunit composition, hormone signaling, wound

164 omain V of the 23S/25S/28S rRNA of the large ribosomal subunit constitutes the active center for the

165 that the RQC forms a stable complex with 60S ribosomal subunits containing stalled polypeptides and t

166 tamycin, allowing functional analysis of 40S ribosomal subunits containing synthetic 18S rRNAs by sel

167 The resulting ribosomal subunits could be specifically labeled in livi

168 Although ribosomal subunit dissociation and nascent peptide degra

169 nteract with both the ribosome and the small ribosomal subunit during stress response.

170 utward movement of the L1 stalk of the large ribosomal subunit during the subunit-joining step of tra

171 Modulation of mRNA binding to the 40 S ribosomal subunit during translation initiation controls

172 Association of the two ribosomal subunits during the process of translation ini

173 tein (EGFP) reporter fused to the L10a large ribosomal subunit (EGFPL10a).

174 -initiation complex (PIC) containing the 40S ribosomal subunit, eIF1, eIF1A, eIF3, ternary complex (e

175 A selective autophagic pathway for 60S ribosomal subunits elicited by nitrogen starvation in ye

176 o require dissociation of eIF1 from the 40 S ribosomal subunit, enabling irreversible GTP hydrolysis

177 ient peptide segments from the cores of both ribosomal subunits enhance RNA polymerase ribozyme (RPR)

178 rsally conserved rRNA structure of the small ribosomal subunit essential for protein synthesis.

179 ion complex (43S PIC), consisting of the 40S ribosomal subunit, eukaryotic initiation factors (eIFs)

180 factor for bulk mRNA and also contributes to ribosomal subunit export.

181 being essential, Rli1p activity (in nuclear ribosomal-subunit export) was shown to be impaired by mi

182 enabling the factor to engage the 40S small ribosomal subunit for translation initiation.

183 chanism of inhibition of a key step in large ribosomal subunit formation.

184 re was modeled onto the structure of the 30S ribosomal subunit from E. coli, suggesting the possibili

185 e present the crystal structure of the large ribosomal subunit from Staphylococcus aureus, a versatil

186 We examined 50 S ribosomal subunits from 10 species and found a clear dis

187 Assembly of 30S ribosomal subunits from their protein and RNA components

188 f the L1 stalk, a mobile domain of the large ribosomal subunit, have been shown to accompany the elon

189 ilis that facilitate the assembly of the 50S ribosomal subunit, however their roles in this process a

190 omes in persisters exist largely as inactive ribosomal subunits, (ii) rRNAs and tRNAs are mostly degr

191 cytosine RNA methyltransferase, to the large ribosomal subunit in a process crucial for mitochondrial

192 bgA is involved in the assembly of the large ribosomal subunit in Bacillus subtilis, and homologs of

193 tal structure at 3.1 A resolution of the 30S ribosomal subunit in complex with the anticodon stem loo

194 crystal structures of the eubacterial large ribosomal subunit in complex with them.

195 ecoding site of the Thermus thermophilus 30S ribosomal subunit in complexes with cognate or near-cogn

196 uired for complete modification of the small ribosomal subunit in Escherichia coli.

197 ometer-scale diffusive properties of the 50S ribosomal subunit in live Caulobacter cells.

198 KRIPP1 and KRIPP8 as components of the small ribosomal subunit in mammalian and insect forms, but als

199 We found that L13a is released from the 60S ribosomal subunit in response to infection by respirator

200 hRio2, are associated with precursors of 40S ribosomal subunits in human cells.

201 Binding of Met-tRNAi to the small (40S) ribosomal subunit, in a ternary complex (TC) with eIF2-G

202 e, 50S, ribosomal subunit to the small, 30S, ribosomal subunit initiation complex (IC) during bacteri

203 initiation, 43S complexes, comprising a 40S ribosomal subunit, initiator transfer RNA and initiation

204 The binding interface on the large ribosomal subunit is buried by the small subunit during

205 t the timely removal of ERAL1 from the small ribosomal subunit is essential for the efficient maturat

206 study shows that nuclear export of the large ribosomal subunit is regulated by a GTPase that blocks r

207 The delivery of Met-tRNA(i) to the 40S ribosomal subunit is thought to occur by way of a ternar

208 ubunits and that its incorporation into 60 S ribosomal subunits is a prerequisite for subunit joining

209 The assembly of the ribosomal subunits is facilitated by ribosome biogenesis

210 ltiple proteins of the small and large yeast ribosomal subunits is suppressed.

211 h-resolution structures for eukaryotic large ribosomal subunits, it remained unclear how these ribonu

212 data highlight the dynamics of IF2-dependent ribosomal subunit joining and the role played by the N t

213 The role of ribosomal subunit joining in marrow failure warrants fur

214 Ribosomal subunit joining is a key checkpoint in the bac

215 on by selectively increasing the rate of 50S ribosomal subunit joining to 30S initiation complexes (I

216 3S pre-initiation complex (PIC) assembly, to ribosomal subunit joining.

217 Maturation of the large ribosomal subunit (LSU) in eukaryotes is a complex and h

218 ve cleavage sites of the kinetoplastid large ribosomal subunit (LSU) rRNA chain, which is known to be

219 proteins involved in pre-rRNA processing and ribosomal subunit maturation have yet to be identified.

220 ins, associates with the mitochondrial large ribosomal subunit (mt-LSU).

221 Following success in the reconstitution of ribosomal subunits, my efforts focused more on ribosomes

222 In the small ribosomal subunit of budding yeast, on the 18S rRNA, two

223 translation enhancers (3'CITEs) that bind to ribosomal subunits or translation factors thought to ass

224 ne specific step in maturation of yeast 60 S ribosomal subunits: processing of 27SB pre-ribosomal RNA

225 insufficiency of Mrpl40 (mitochondrial large ribosomal subunit protein 40) as a contributor to abnorm

226 he yeast Saccharomyces cerevisiae, the large ribosomal subunit protein Rpl3p is methylated at histidi

227 tomatitis virus (VSV), we identify the large ribosomal subunit protein rpL40 as requisite for VSV cap

228 o catalyze prolyl-hydroxylation of the small ribosomal subunit protein RPS23.

229 otein Yar1 directly interacts with the small ribosomal subunit protein Rps3 and accompanies newly syn

230 green fluorescent protein (eGFP)-tagged L10a ribosomal subunit protein under control of the collagen1

231 serine/threonine residues in the human small ribosomal subunit protein, receptor for activated C kina

232 We visualize ribosomal subunit proteins and show that the large subun

233 ation of Rps2, Rps3, and Rps27a, three small ribosomal subunit proteins in the yeast Saccharomyces ce

234 NA metabolism, including the large and small ribosomal subunit proteins L10a and S6, the stress granu

235 The 3'UTR interacts with 40S ribosomal subunit proteins residing primarily in a local

236 uding genes encoding translation factors and ribosomal subunit proteins.

237 linked the evolution of the large and small ribosomal subunits, proto-mRNA, and tRNA.

238 n assembly of bacterial and eukaryotic large ribosomal subunits, providing insights into how these RN

239 factors required for maturation of the small ribosomal subunit (Rcl1, Fcf1/Utp24, Utp23) and the larg

240 f PABP-eIF4G on cap binding to promote small ribosomal subunit recruitment.

241 During translation, the two eukaryotic ribosomal subunits remain associated through 17 intersub

242 Recruitment of mRNA to the 40S ribosomal subunit requires the coordinated interaction o

243 on and inhibit the nuclear export of the 60S ribosomal subunit, respectively.

244 ple EF-G catalysed translocation from normal ribosomal subunit reverse-rotation, leaving the ribosome

245 al surveillance, acts as an inhibitor of 60S ribosomal subunit ribophagy and is antagonized by Ubp3.

246 ide bond is formed, a reaction that requires ribosomal subunit rotation and is catalyzed by the guano

247 rmation that favors an intermediate state of ribosomal subunit rotation.

248 erichia coli ribosome in different states of ribosomal subunit rotation.

249 ecovered from cells expressing both a tagged ribosomal subunit, Rpl10a, and the bacterial biotin liga

250 n its ATPase motifs lead to defects in small ribosomal subunit rRNA maturation, the absence of riboso

251 epending on additional mutations that modify ribosomal subunit S6 or one of three subunits of RNA pol

252 ion of tRNAs and translation factors to both ribosomal subunits, showing that its effects span all as

253 e proteins depends on interactions with both ribosomal subunits, some portion of 30S and 50S assembly

254 omal protein L13a is released from the large ribosomal subunit soon after infection and inhibits the

255 gh mobility group protein Hmo1 and the small ribosomal subunit (SSU) processome complex.

256 rRNA) processing as a component of the small ribosomal subunit (SSU) processome.

257 KsgA, a universally conserved small ribosomal subunit (SSU) rRNA methyltransferase, has rece

258 y a novel mammalian complex required for 60S ribosomal subunit synthesis, providing further insight i

259 nce to linezolid (and a variety of other 50S ribosomal subunit-targeted antibiotics) but not to tediz

260 Multiple interactions between the ribosomal subunits, termed intersubunit bridges, keep th

261 L27 is a component of the eubacterial large ribosomal subunit that has been shown to play a critical

262 Defects in RbgA give rise to a large ribosomal subunit that is immature and migrates at 45 S

263 e structures of three complexes of the small ribosomal subunit that represent distinct steps in mamma

264 tion conditions, they accumulated incomplete ribosomal subunits that we named 45SYphC and 44.5SYsxC p

265 neighboring proline residue resulting in 40S ribosomal subunits that were blocked from polysome forma

266 he model explains the evolution of the large ribosomal subunit, the small ribosomal subunit, tRNA, an

267 ken eIF3 binding to the HCV IRES and the 40S ribosomal subunit, thereby suppressing eIF2-dependent re

268 G3BP interacts with 40S ribosomal subunits through its RGG motif, which is also

269 m whereby initiation factors recruit the 40S ribosomal subunit to a cap structure at the 5' end of th

270 nitiation factors needed to recruit the 40 S ribosomal subunit to an mRNA.

271 factors involved in the recruitment of a 40S ribosomal subunit to an mRNA.

272 ding of initiator tRNA and mRNA to the small ribosomal subunit to form the initiation complex, which

273 sively in the cytoplasm and binds to the 40S ribosomal subunit to gain access to translating mRNAs, M

274 mplex and stimulates its assembly to the 50S ribosomal subunit to make the 70S ribosome.

275 eIF4A modulates the conformation of the 40S ribosomal subunit to promote mRNA recruitment.

276 e array of initiation factors onto the small ribosomal subunit to select an appropriate mRNA start co

277 he 5'-UTR, allowing eIF4F to recruit the 40S ribosomal subunit to the 5'-end.

278 Joining of the large, 50S, ribosomal subunit to the small, 30S, ribosomal subunit i

279 t is active translation that normally allows ribosomal subunits to assemble on nascent mRNAs througho

280 ether with eIF3 and eIF4A/4B, eIF4G recruits ribosomal subunits to mRNAs and facilitates 5' untransla

281 bitors are enhanced by the limited access of ribosomal subunits to nascent mRNAs in the compacted nuc

282 action with a 5' proximal hairpin to deliver ribosomal subunits to the 5' end for translation initiat

283 Ltn1 binds to 60S ribosomal subunits to ubiquitylate nascent polypeptides

284 y a process mediated specifically by the 30S ribosomal subunit, to degrade defective 70S ribosomes bu

285 on of the large ribosomal subunit, the small ribosomal subunit, tRNA, and mRNA.

286 The L1 stalk of the large ribosomal subunit undergoes large-scale movements couple

287 cation, relative to protein S12 of the small ribosomal subunit using single-molecule FRET.

288 peptidyl-tRNA enters the P site of the small ribosomal subunit via reversible, swivel-like motions of

289 Binding of salt-washed 40S ribosomal subunits was reduced 6-fold when the pyrimidin

290 both function during maturation of the small ribosomal subunit, we show here that Rrp5 provides speci

291 c are defective in the maturation of the 60S ribosomal subunit, whereas maturation of the 40S subunit

292 The creation of orthogonal large and small ribosomal subunits, which interact with each other but n

293 iquitinated polypeptides associated with 60S ribosomal subunits, while Dom34-Hbs1 generate 60S-associ

294 tes of protein modification within the small ribosomal subunit will now allow for an analysis of thei

295 ctor important for the assembly of the small ribosomal subunit with an uncommon dual ATPase and adeny

296 the nascent peptide exit tunnel of the large ribosomal subunit with comparable affinities, the bacter

297 (34);ms(2)t(6)A(37);Psi(39) bound to the 30S ribosomal subunit with each codon in the A site showed t

298 Here, we labeled human 40S ribosomal subunits with a fluorescent SNAP-tag at riboso

299 -shaped structures can bind to ribosomes and ribosomal subunits, with one structure also able to enga

300 ract with each other but not with endogenous ribosomal subunits, would extend our capacity to create