ライフサイエンスコーパス: rigid

1 ain that would otherwise be conformationally rigid.

2 74 series assume that the crystal lattice is rigid.

3 cated, indicating that desmin aggregates are rigid.

4 work describes vicinal diols, tethered to a rigid 1,3-diethynylbenzene core, as pivotal moieties for

5 The pyrene excimer formed by two rigid 1-pyrenecarboxamide residues showed the brightest

6 es place over a short path (8.8 mm) within a rigid, 12 mm long, perforated probe tip.

7 A prime example is binding of the rigid 14-3-3 adapter proteins to their numerous partner

8 luding generating plaids that do not contain rigid 2D motion.

9 t was associated with facial hypomimia and a rigid akinetic syndrome only in the patient's left hemib

10 ower factor of 0.62 mW/(m K(2) ) at 684 K on rigid Al2 O3 substrate and 0.46 mW/(m K(2) ) at 664 K on

11 the SiO2 surface toward the well-ordered and rigid alkane self-assembled layers.

12 ty of chiral lipophilic and conformationally rigid amines and heterocycles by decarboxylation of adam

13 not captured when modeling this framework as rigid, an approximation typically made in high-throughpu

14 es as a microscale elastic connector for the rigid and brittle perovskite and induces stretchability

15 find that binding of GTP analogs leads to a rigid and closed arrangement of the Galpha subdomain, wh

16 ion bonds played a key role in rendering the rigid and coplanar conformation of these molecules and t

17 mple but generic rule, without recourse to a rigid and deterministic sequence of genetically programm

18 osteric ligands tend to be more aromatic and rigid and do not confirm the increase in hydrophobicity

19 , a reasonably high electron affinity, and a rigid and extended delocalized pi-system.

20 For high-mobility applications, both rigid and flexible radio-frequency graphene field-effect

21 of 17.10% and 14.19%, with no hysteresis on rigid and flexible substrates, respectively, which are t

22 ies on transparent conductive oxides on both rigid and flexible substrates.

23 licon micromachining processes, resulting in rigid and low aspect ratio structures.

24 nd (1)H NMR studies show that aza-DKP 4 is a rigid and nonflat scaffold like the 2,5-DKP 7.

25 ich addresses critical issues of an existing rigid and planar electrode combined with a problematic c

26 The LPS layer is rigid and stabilized by divalent cation cross-links betw

27 t from constraints imposed by the relatively rigid and sterically bulky repeating units.

28 molecular charge-transfer (CT) dynamics of a rigid and strongly conjugated perylenediimide-bridge-per

29 on of the main head-tail interface, which is rigid and undergoes very limited fluctuations, despite t

30 TlInTe2, with interlocked rigid and weakly bound substructures, exhibits lattice t

31 mulate contain an amine, are amphiphilic and rigid, and have low globularity.

32 like' sub-lattice of cations mobile within a rigid anionic sub-lattice, often achieved at high temper

33 ry that already maximizes selectivity in the rigid approximation is continuously diminished with incr

34 The covalent polymer has a rigid aromatic imine backbone with helicoidal conformati

35 utical guest molecules as opposed to planar, rigid aromatics, was synthesized via the Weak-Link Appro

36 chanical properties; the rod is straight and rigid as a drive shaft whereas the hook is flexible in b

37 o cover 30-40% of a tube's surface to form a rigid assembly.

38 piperidine ring that provides a structurally rigid backbone and facilitates the installation of other

39 om the integration of alkyne groups into the rigid backbone and the delocalized pi-conjugated structu

40 rt of show a clear trend toward conserving a rigid backbone.

41 ver, for three architectures which have more rigid backbones (fewer than five rotatable bonds), intra

42 To do this, the Rigid Band model is generalised for magnetic systems in

43 e side chains of L5, V54, and V29 are highly rigid because they are packed in the core of the protein

44 stly to N- and C-terminal regions within the rigid beta structure in the repeat region of Tau(3RD).

45 We identified a flexible region within the rigid beta-subdomain that gives way under load, thus ope

46 The rigid bicyclic skeleton of 2,4-methanoprolines allowed u

47 uum approach could help staff move away from rigid binary judgments and train them to adopt formal ca

48 er entropy penalty, compared with other more rigid binders, and highlights a new strategy for inhibit

49 distribution of amino acids in the small and rigid binding surface of enriched rcSso7d-based binders

50 matic linkage, with fixed groups of atoms as rigid bodies and rotatable bonds as degrees of freedom.

51 These are self-assembled chains of rigid bodies with an inversion centre and no reflection

52 e of VVD on its overall dynamics by applying rigid body constraint on each residue in molecular dynam

53 sed docking method to quickly perform global rigid body docking of these fragments to the receptor.

54 these restraints, pseudocontact shift-based rigid body docking together with molecular dynamics simu

55 s Pointed (PNT) domain, engages in a largely rigid body interaction with a section of the ERK2 F-recr

56 too complicated to be fully represented with rigid body kinematics.

57 hat organ of Corti mechanics are governed by rigid body kinematics.

58 t domain binds to the substrate and, through rigid body motions, transports it across the membrane.

59 ain rotation model but inconsistent with the rigid body reorientation model given the increased flexi

60 d allostery were systematically assessed via rigid body simulations of both unbound and ligand-bound

61 e model structure evaluation methods perform rigid body superimposition of a structure model to its c

62 alignment tools for template-based modeling, rigid body transformation controls, RosettaScripts suppo

63 binding site in a multi-specific ligand as a rigid body.

64 Increasing rigid-body diversity of the models using RosettaDock's l

65 ned de novo method for homology modeling and rigid-body docking and present the results for 1) the An

66 g algorithm for exhaustive fragment-receptor rigid-body docking and Rosetta FlexPepDock for flexible

67 p and model, and does not require an initial rigid-body fitting step.

68 Our simulations show that large rigid-body motions of the transport domain (55 degrees i

69 ctures, but another displayed more extensive rigid-body shifts as well as dramatic secondary structur

70 ation) and solution X-ray scattering data in rigid-body simulated annealing calculations provides a p

71 ysis confirm the formation of an asymmetric, rigid, box-like cyclophane, DAPPBox(4+).

72 in reality the DNA is densely packed, is not rigid but highly mobile, and the dynamics of DNA dictate

73 reading and rigidity-sensing contractions on rigid, but not soft, substrates.

74 tem from the fact that fear memories are not rigid, but reorganize over time.

75 and allows for a structure refinement using rigid carbonate groups.

76 te that the close steric fitting between the rigid cavity of 1 and the pyridinium guest is the crucia

77 The holoenzyme is organized by a rigid central hub complex, while positioning of the kina

78 ngly some of these vibrations involve unique rigid-chain vibrations and S-S molecular oscillations.

79 exible "open" configuration and a collapsed, rigid "closed" one.

80 ryl-terminated linkers produces size-tunable rigid cluster nanomolecules.

81 a cocaine aptasensor based on a structurally rigid cocaine aptamer variant (MN4), an aptasensor refer

82 The data explain why rigid collagen fibrils potentiate PI3K activation to pro

83 This model limitation is rigid commitment which never changes.

84 ble, less structured, and topologically less rigid compared to ApoE3.

85 ow that the H4 histone is significantly more rigid compared with the H3 histone and its variant CENP-

86 region (LIR) to LC3B and formation of a very rigid complex compared to the non-phosphorylated sequenc

87 ition, most proposed designs use one or more rigid components that fail to meet the stretchability re

88 (35)S]GTPgammaS assay showed that structural rigid compounds having the 3-hydroxyphenyl group locked

89 present day and to maintain ocean uplift, a rigid, conductive water-ice shell is required.

90 Upon heating, microbombs anchored in rigid confinement underwent balloon-like blowing up, all

91 quence that is almost entirely arranged in a rigid conformation, and confirm a beta-sheet structure i

92 design when using a method that is based on rigid conformations.

93 rmance of the macrocycle originates from its rigid, conjugated, and cyclic structure.

94 Its rigid connection to the kalata B1 backbone scaffold, tog

95 joined by a shared helix in such a way that rigid connector modules are formed.

96 This approach, outside of the rigid constraints of the ribosome and enzymatic processi

97 Thick, rigid continents move over the weaker underlying mantle,

98 hat terrestrial DOM consist of a hydrophobic rigid core surrounded by progressively assembling amphip

99 NMR, we directly probe the structure of the rigid core that is at the heart of huntingtin exon1 fibr

100 oportion of the flexible alkyl corona to the rigid core, mesomorphic behavior of one compound could b

101 oporous materials were traditionally seen as rigid crystalline structures, there is growing evidence

102 results in tandem cascading reactions within rigid cyclophanes, where reactions at a first triple bon

103 However, cells on rigid/dense fibers were also more susceptible to injury

104 s ETM can show a high efficiency over 17% on rigid device and 14.2% on flexible PVSC.

105 doublet, thus demonstrating the potential of rigid diamide ligands in the design of new SIMs with def

106 f-assembly was nucleated and confined inside rigid DNA nanotemplates.

107 Here, we report a synthetic strategy using rigid DNA scaffolds to similarly program the spatial org

108 ng evidence suggests that stress favors more rigid dorsal striatum-dependent habit memory, at the exp

109 tudy, we analyze smFRET data of structurally rigid, double-stranded DNA-oligonucleotides in aqueous b

110 The aromatic polyimide, which is more rigid due to the stronger charge transfer complex betwee

111 n lapse rate and derive biotic velocity as a rigid elevational shift.

112 tric endoscope with minimal alterations to a rigid endoscope.

113 rface of the vocal folds with fiber-optic or rigid endoscopy and using stroboscopic or high-speed vid

114 Materials with rigid, engineered pore structures add an additional degr

115 n scalable membrane materials based on these rigid features, for both gas and liquid phase applicatio

116 Utilizing a rigid ferrocene diamide ligand (NN(TBS)), a Dy(III) SIM,

117 ly in the limit of dilute concentrations and rigid fibers; at the other extreme, however, where the s

118 By contrast, rigid filament bundles slide without bending under motor

119 ely flexible single-stranded RNA into a more rigid filamentous structure elevates the pressure within

120 this gene plays a role in the acquisition of rigid flippers for efficient manoeuvring.

121 is significantly reduced relative to that of rigid fluid-lubricated contacts.

122 monstrated that the two molecules had common rigid folding core and dynamic regions and provided stru

123 on the plantar flexors, as walking on a more rigid foot/shoe surface compromises the plantar flexors'

124 hanges GAX mobility in a complex manner: the rigid fraction of GAX became more rigid upon EXPB1 bindi

125 Rigid gas permeable wearers should avoid exposing their

126 e coated on a range of substrates, including rigid glass and flexible plastic.

127 OIHP devices is far behind those achieved on rigid glass substrates.

128 ze that visualization techniques without the rigid grid constraint of cluster heatmaps will perform b

129 After exchanging for a rigid guidewire, conventional TAVR was performed through

130 h either a short flexible linker or a set of rigid helical linkers.

131 hly stretched, almost planar and practically rigid helical structure, inert to external stimuli and p

132 teraction with the ligands, whereas the more rigid holoprotein structure protects the labile retinoid

133 nd single-stranded alpha-helix in the highly rigid hydrogel of native agarose, while the considerably

134 st widespread biological role is providing a rigid hydrophobic contact surface under the undecorated

135 Notably, the protein-RNA complex is rigid in the presence of a strong Py-tract but exhibits

136 guanidino groups were found to be remarkably rigid in the TSA complex, indicating that the enzyme has

137 -bound/occluded states are much more stable (rigid) in the OF than in the IF state.

138 Furthermore, we show that the embedded rigid inclusions markedly facilitate stretch-induced mem

139 al to the incoherent sum of diffraction from rigid individual molecular complexes aligned along sever

140 These form a rigid interaction through a conserved interdomain interf

141 However, gliding eleutherodonts possess rigid interclavicle-clavicle structures, convergent to t

142 tron wave probes the fluctuations close to a rigid interface.

143 A thicker hydration shell and a more rigid interfacial hydration network are observed in the

144 y (ECD) after the implantation of 2 types of rigid iris-fixated phakic intraocular lenses (pIOLs) for

145 the dissociation of CN(-), leading to a less rigid kappa(2)-phosphoramidite-neutral Pd intermediate.

146 to cyclodehydrogenation with FeCl3 to access rigid ladder type polymers with the conversion investiga

147 terials can sustain nanoscale pores in their rigid lattices and due to their minimum possible materia

148 ct (520 microm in outer diameter and 5 mm in rigid length) and super-achromatic microprobe made with

149 We found that a rigid, lesion-like matrix inhibited branching and differ

150 in the time variation of flow dynamics for a rigid-lid cavity problem under both up-scaled and down-s

151 We insert GFP into the rigid, ligand-binding head of the integrin, model with R

152 plet state delocalization is investigated in rigid linear zinc porphyrin oligomers as a function of i

153 Thus value coding in OFC is functionally rigid (linear tuning) but parametrically plastic (range

154 g between alkynes to generate a structurally rigid, linear 1,3-diyne linkage has been known for over

155 Thus, the manner in which the rigid lithosphere couples to the flowing asthenosphere i

156 nce the removal of the phenyl rings from the rigid loop restores drug transport activity.

157 h its crystallographically demonstrated more rigid loop.

158 ong with a variety of synthetic flexible and rigid macrocycles that have drawn their inspiration from

159 ures that explain how orthologs can generate rigid macrocyclic scaffolds of different sizes.

160 help ameliorate poor packing geometry of the rigid main particle at the angled edges.

161 egrated microfluidic devices fabricated from rigid materials is confined to expensive and complex met

162 achieve with conventional robots composed of rigid materials.

163 exible electronics with these conventionally rigid materials.

164 -friendly solid-state films is difficult for rigid materials.

165 Rigid matrices are further required for eventual express

166 Rigid matrix is needed to induce rapid nuclear accumulat

167 e maps, the spatial distribution of soft and rigid matrix polymers could be visualized in the context

168 The peptidoglycan is a rigid matrix required to resist turgor pressure and to m

169 O-MOFs therefore creates MOFs that have more rigid mechanical properties over a larger pressure range

170 bined with an analysis that incorporated non-rigid mechanics, we quantified the total work production

171 hort-term nZVI exposure, resulting in a more rigid membrane counteracting the membrane-fluidizing eff

172 dicated by smaller colony morphology, a more rigid membrane, and higher tolerance to nZVI.

173 se they are protease resistant, structurally rigid, membrane permeable, and capable of modulating pro

174 was manifested in the form of more ordered, rigid membranes, with the pure POPC being affected to a

175 Here, in cancer cell migration through rigid micropores and in passive pulling into micropipett

176 Furthermore, through the sparse addition of rigid microtubule filaments, one can gain additional con

177 tions, we study a dense, confined mixture of rigid microtubules (MTs) and active springs that have ar

178 finding was further supported by independent rigid modeling.

179 o promote gas transport, and the unique soft-rigid molecular structure of triblock copolymers can acc

180 m flexible polymer membranes and traditional rigid molecular-sieve membranes.

181 structural data suggested that TF binds as a rigid molecule to the ribosome, recent comparisons of st

182 Our results suggest that the presence of rigid molecules in cellular membranes could serve as "me

183 llosteric compounds tend to be smaller, more rigid, more hydrophobic, and more drug-like than non-all

184 Organ motion was tracked by assuming rigid motion (translation and rotation) and appropriate

185 cokinetic analysis was carried out after non-rigid motion registration.

186 s study, we demonstrate a method to build up rigid multivalent and multispecific scaffolds by exploit

187 receptor dynamics are observed ranging from rigid nanobody-coupled states to extensive mus-to-ms tim

188 rapped pockets of the ice cream mixture in a rigid network.

189 With Pd(II) cations as rigid nodes, the pure distinctly angular components read

190 the neurotransmitter transporter activity of rigid nucleosides while reducing A3AR affinity.

191 on of MoS2 nanosheets vertically rooted into rigid one-dimensional TiO2 nanofibers.

192 nd low-cost production of nanoelectronics on rigid or mechanically flexible substrates.

193 ing processes, whereas others are relatively rigid or reflexive.

194 ft-templating strategies, different types of rigid or vesicle templates are used for making YSNs.

195 ble spin-labeled positions indicate a rather rigid orientation of the POTRA domains in frozen liquid

196 iquid electrolyte and do not require robust, rigid packaging for containment.

197 rinsically disordered recognition motif to a rigid partner protein.

198 nfection cell, leading to the formation of a rigid penetration peg.

199 rce to rupture the rice leaf cuticle using a rigid penetration peg.

200 and bind different ligands, DMF5 uses a more rigid, permissive architecture with greater reliance on

201 More rigid piperidines provided the highest selectivity of th

202 de a much needed reliable valving scheme for rigid plastic devices with low complexity, low cost, and

203 ods, based on trilayer samples consisting of rigid plastic stripes sandwiching a swellable temperatur

204 materials comprising a periodic assembly of rigid plates and elastic hinges.

205 Apart from the electroless rigid platform, the rest demonstrated comparable and sup

206 In vitro results are presented from two rigid platforms (32 ISEs) for liquid sample dip-stick me

207 pH greater than the electroless flexible and rigid platforms, respectively.

208 hat bridges the phospho-acceptor site to the rigid PNT domain.

209 In this approach, non-rigid point-set registration is used to match each segme

210 tic links between side chains that give it a rigid polycyclic globular structure.

211 New rigid polyimides with bulky CF3 groups were synthesized

212 ort a new approach to designing crosslinked, rigid polymer nanofilms with enhanced microporosity by m

213 concentration is shown to provide for a more rigid polymer network than the conventional 7.5% polyacr

214 microporous polymers may be applied to other rigid polymers for gas separations.

215 ggregation-accelerating N terminus, and semi-rigid polyproline II helices in the proline-rich flankin

216 wo distinct spin reservoirs, a small initial rigid population and a majority-component mobile distrib

217 ted clinical trials as small, scientifically rigid population studies that generate outcomes focused

218 inert passing of the cytochrome C through a rigid pore, the flexible pore may selectively aid the cy

219 optimal separation exists within an entirely rigid pore.

220 from a combination of the contributions of a rigid, predominantly fast-firing subset of pyramidal neu

221 densely packed chromophore aggregates using rigid protein scaffolds to achieve highly efficient, dir

222 XPD in contrast is shown to be a rigid protein with almost no conformational changes resu

223 f sPRE beyond structural characterization of rigid proteins and complements the established PRE NMR t

224 broader question may be posed: insertion of rigid proteins in soft membranes ought to stiffen the me

225 bservations perplexingly appear to show that rigid proteins may either soften or harden membranes eve

226 This unique and relatively rigid pyranose backbone contributes to their defined hel

227 O-t-Bu), which contains the conformationally rigid pyridine-based diamido ligand, [2,6-(ArNCH2)2NC5H3

228 Drawbacks include a more rigid regimen, a relative lack of flexibility, and a som

229 ns involved in consuming drugs may involve a rigid repertoire of habitual behaviors, evidence suggest

230 The projection of simulations with rigid residue perturbation onto coherent allosteric mode

231 al component analyses of simulations without rigid residue perturbation showed a coherent allosteric

232 model system to advance a recently developed rigid residue scan method combining with configurational

233 a recently developed computational approach, rigid residue scan(RRS), to systematically probe the imp

234 -healing, those derived from lipoic acid are rigid, resilient, and brittle.

235 isting of two ping-pong balls connected by a rigid rod, and its two balls are filled with granular pa

236 s was used to create a library of homologous rigid-rod 310-helical foldamers, which have incrementall

237 on of ionic liquid and magnetically oriented rigid-rod polyanion provides widely tunable properties f

238 radical cation in three homologous series of rigid-rod-like donor-photosensitizer-acceptor triads wit

239 lar, we first model dsDNA molecules as short rigid rods containing periodically spaced binding sites.

240 4-dimensional treatment, which validates the rigid-rotor approach widely used in scattering calculati

241 research relates predictable environments to rigid routine behaviors and aggression.

242 ofactor involved in fixing nitrogen is not a rigid scaffold, as was previously thought.

243 t that geometric constraints, in this case a rigid scaffold, can have on the reactivity of main group

244 carefully designed protein with a subtle and rigid secondary structure that enables the binding of su

245 olyethylene glycol (PEG) conjugates and (ii) rigid self-assembled DNA.PNA complexes.

246 stent with quasiparticles injection across a rigid semiconducting gap.

247 demonstrate alpha adaptation, highlighting a rigid, set mode of sensory hyperactivity.

248 c transcript abundance ratio that underlie a rigid SFA:MUFA:PUFA hierarchy in triacylglycerol (TAG).

249 Their rigid shape, featuring an almost planar N-arylamine and

250 lecules drives the formation of a stable and rigid shell wall, and these unique structures allow enca

251 In particular, the dense and rigid sickle RBCs are obstructed thereby clogging blood

252 ultralow diameter of around 100 nm and the "rigid-soft" system crosslinked by nanocrystal domains li

253 lent photodynamic activity resulted from the rigid spatial arrangement of the quaternized triazole mo

254 Lipid nanocapsules (LNCs) are semi-rigid spherical capsules with a triglyceride core that p

255 g-range distance and angle measurements with rigid spin labels provide critical input for the refinem

256 LDOR/DEER) experiments of nucleic acids with rigid spin labels provide highly accurate distance and o

257 cs in response to nutrient shifts owing to a rigid strategy of protein synthesis allocation, which is

258 in high yields (>90%), due to the intrinsic rigid structural conformation of the precursor BODIPY an

259 The rigid structure of DWNTs ensures high modulation depth (

260 However, the rigid structure of tRNA has been presenting a challenge

261 ted ensembles of the active mutants showed a rigid structure with few adoptable conformations while i

262 s, while static macrophages (MF) form a more rigid structure, often encasing the islet cell mass.

263 wed that four of the protein modules adopt a rigid structure, which stabilizes the catalytic domain.

264 ly nonfluorescent, despite having a similar, rigid structure.

265 hout compromising activity, whereas bulk and rigid substituents in 5'-position appear unfavorable.

266 red by overcrowding the nodes with bulky and rigid substituents.

267 ulating the morphology of migratory cells on rigid substrates in cell culture are widely known, how s

268 Compared to conventional culture on rigid substrates or unpatterned hydrogels, MP substrates

269 Conforming materials to rigid substrates with Gaussian curvature-positive for sp

270 By contrast, on rigid substrates, cells develop extensive adhesions, inc

271 gly drives lamin-A-dependent osteogenesis on rigid substrates, with pretreated xenografts calcifying

272 urface holograms are typically fabricated on rigid substrates.

273 able to those of high performance sensors on rigid substrates.

274 entropy when individual residues being held rigid support that the rigidity/flexibility equilibrium

275 The nanosystem contains a rigid supporting dumbbell-shaped frame, a cylindrical ce

276 al micro-object in adhesional contact with a rigid surface.

277 cquire images of regions where shoes contact rigid surfaces.

278 Fitting to a semi-rigid symmetric top model supports predictions of two co

279 Changes in measured (DT)CCSHe for these rigid systems at different temperatures are attributed p

280 oundaries to the center, squeezed up by more rigid tectonic blocks in the north and south.

281 - and moisture-stable PCP metalloligands are rigid tetratopic linkers that are geometrically akin to

282 both size exclusion (PFDT is larger and more rigid than DT), and the oleophobicity of PFDT.

283 e helices were found to be considerably less rigid than many other natural and synthetic polymers, as

284 and unable to assemble a MinE ring, is more rigid than WT MinE.

285 tructural alteration in omega6 makes it more rigid, the plasticity of the interacting domain formed b

286 ents that are optimized and maintained using rigid thermal cycling programs and stringent sample prep

287 EC9-10 confers some elasticity to otherwise rigid tip links.

288 he FM (AFM) phase, its magnetization is more rigid to external E-field.

289 r cushioning while the outer shell should be rigid to provide protection.

290 Studies of electron spin relaxation rates in rigid trehalose/sucrose matrices reveal approximately te

291 enantiomeric naphthalenediimide-based highly rigid triangles R-Delta and S-Delta in ClCH2CH2Cl are mi

292 large, multi-domain MDGA molecules fold into rigid triangular structures, cradling a dimeric NL to pr

293 )terpyridine (H2Tpy(NMes)) was prepared as a rigid, tridentate pincer ligand containing pendent anili

294 copic objects apart through a burst of their rigid tubular structure.

295 leavages during cell entry, whereas the more rigid uncleaved MERS viruses trafficked past these cell-

296 anner: the rigid fraction of GAX became more rigid upon EXPB1 binding while the dynamic fraction beca

297 mobility in the apoprotein that became more rigid upon retinoid binding.

298 hydrophobic binding cavity; construction of rigid urea functionalities on the upper rim; and the int

299 mally disordered, hyperuniform, mechanically rigid with infinite bulk and shear moduli, and can never

300 rements indicated that the Rfr-fold core was rigid with order parameters ranging from 0.7 to 0.9.