ライフサイエンスコーパス: rigidly

1 s human infants to perform habitual behavior rigidly.

2 groove binding A-B-C+ risaccharide moieties rigidly anchor the enediyne in the minor groove such tha

3 one, indicating that the fatty acids are not rigidly anchored in the cavity, but move within the pock

4 support the view that the fatty acid is not rigidly anchored within the I-FABP binding pocket, but r

5 ts suggest that this isozyme participates in rigidly anchoring stereocilia; and finally, colocalizati

6 es were registered with simulation CT images rigidly and by using four deformable image registration

7 of protein flexibility via identification of rigidly and nonrigidly repositioned fragments, stable an

8 oxyl-4-amino-4-carboxylic acid, the probe is rigidly and stereospecifically coupled to the alpha-carb

9 y light chain (RLC) using a spin-label bound rigidly and stereospecifically to the single Cys-154 of

10 These bonds hold the transition structure rigidly and thus allow the catalyst triphenylsilyl group

11 andem death effector domains (DEDs) of MC159 rigidly associate with each other through a hydrophobic

12 ld of DED1, a dumbbell-shaped structure with rigidly associated DEDs and a different mode of interact

13 ely, on bare Al2O3, the latex particles were rigidly attached as compared to the more loosely attache

14 Spin labels that are more rigidly attached to a base in an oligonucleotide experie

15 The SUN2 domain is rigidly attached to a trimeric coiled coil that preposit

16 in vitro as single molecules or as ensembles rigidly attached to nonbiological substrates.

17 the nitroxide-containing ring covalently and rigidly attached to the alpha-carbon, providing direct i

18 distances between two nitroxide spin labels rigidly attached to the helices of the dimer was determi

19 e feasibility and usefulness of a GFP moiety rigidly attached to the protein of interest as a probe f

20 pproach requires a fluorescent probe that is rigidly attached to the protein of interest.

21 These sound diffusers are rigidly backed slotted panels, with each slit being load

22 ng is a new behavioral mechanism by which MA rigidly biases choice behavior.

23 gid docking and induced fit, with TruB first rigidly binding to its target and then maximizing the in

24 reases in the anisotropy associated with the rigidly bound multiuse affinity probe 4',5'-bis(1,3,2-di

25 and receptors that are tethered rather than rigidly bound on a cell surface.

26 bsence of ATP, when all the myosin heads are rigidly bound to the thin filament), a slight decay was

27 btained; four-eclipsed substituents are held rigidly by the bicyclic addends.

28 ates increased with Ca (systole), suggesting rigidly closed conformations for the E1 (Ca-bound) enzym

29 he uniqueness of gold chemistry applied to a rigidly closed shell system in an unconventional way.

30 bN), reveals a globular entity formed by two rigidly connected cyclin-like folds.

31 Transmission through the rigidly connected plexin/semaphorin/integrin (PSI) domai

32 the virion (domains 1 and 2) are aligned and rigidly connected, whereas domain 3 diverges at an angle

33 ogues as B-class organ-identity genes is not rigidly conserved among all angiosperms.

34 H and S) mutations have been engineered at a rigidly conserved aromatic residue, W63, of the isolated

35 indicates that there are probably no large, rigidly conserved cis-acting nucleic acid sequences requ

36 pgl gene cluster mediates the synthesis of a rigidly conserved heptasaccharide that is attached to pr

37 e of little importance, or that managers are rigidly constrained with no flexibility to adapt, in whi

38 eptor units, relative to the spacer, are not rigidly constrained, and their torsional motions decreas

39 ted that binding of Runx1 to the enhancer is rigidly controlled at the level of chromatin accessibili

40 first chemically assembled into chains with rigidly controlled separations of 0.9 nm primed for re-s

41 If environmental conditions are rigidly controlled, this method is very sensitive for de

42 ellular one-half of S4 during activation are rigidly coupled to lateral movement of the S4-S5 linker,

43 e-binding clefts could be closed if they are rigidly coupled to switch I.

44 l and monomeric PLB mutant with a spin label rigidly coupled to the backbone of the transmembrane hel

45 a thin illumination sheet whose position is rigidly coupled to the objective and aligned with its fo

46 lia are filled with actin filaments that are rigidly cross-linked.

47 tion that cannot be met by a small number of rigidly defined neuronal populations.

48 ay be that the DNA-binding HTH motif becomes rigidly defined only when FlhD forms a complex with some

49 when attempting to model sequences with less rigidly defined structures, such as messenger and non-co

50 aper follows a rather narrowly (but not ever rigidly) defined pattern.

51 e their spacing and that NF spacing does not rigidly determine axon diameter.

52 gesting that phosphorylation of NFs does not rigidly determine their spacing and that NF spacing does

53 plexities of insect reproduction, their more rigidly determined altricial patterns of social behaviou

54 light is polarized in an orientation that is rigidly determined by the position of the sun, this cue

55 oxyl end of the fatty-acid spin label is not rigidly docked on the protein.

56 The filament model obtained by rigidly docking a chicken smooth muscle myosin structure

57 e mobility of radical intermediates but also rigidly encapsulates the substrate, intermediates, and p

58 o not have severe geometric constraints that rigidly enforce unusual geometries.

59 nitial purity and stability of agonists were rigidly ensured and quantitatively assessed.

60 gratory specificity of the LGE precursors is rigidly established between E12.5 and E14.5.

61 that the 5'-adenine of the triloop, which is rigidly fixed ("clamped") to the stem, is a key recognit

62 Isolated whiskers rigidly fixed at the base showed first-mode resonance pe

63 zero in the bound state (i.e., the ligand is rigidly fixed in the binding pocket).

64 The branch points, which are rigidly fixed in these junctions in their free forms, te

65 red by the elasticity modulus) compared with rigidly fixed LH, and also the force needed to initiate

66 We report that Synaptotagmin remains rigidly fixed on the partially assembled SNARE complex w

67 alysis reveal that the tag does not assume a rigidly fixed position, but instead can be found at vari

68 ironment, it was possible to image molecules rigidly fixed to the substrate and the motion of single

69 r hindlimbs, whereas the head and trunk were rigidly fixed.

70 in freely moving animals can be obtained by rigidly fixing ('anchoring') the pipette electrode to th

71 A more rigidly folded D-loop may explain some of the previously

72 joint that has limited movement and is often rigidly guarded.

73 The two rigidly held aromatic rings of SCA-alpha2 form a right-h

74 ior observed for the duplexes containing the rigidly held Ru(II) center originates, at least partiall

75 It is known this C-terminal region becomes rigidly held when FlgM binds sigma 28, and it is possibl

76 reen fluorescent protein (GFP) expressed and rigidly held within the amino acid sequence of a major h

77 ascribed to a hydrophobic environment and a rigidly held, open conformation of NADH, features in acc

78 Klenow fragment the templating base is more rigidly held, so that changes in base pair geometry woul

79 Thus, the results do not support a rigidly hierarchical model of nervous system organizatio

80 This probe is rigidly immobilized on the catalytic domain of the head,

81 emase has a positively charged arginine held rigidly in place by an extensive hydrogen bond network t

82 he TTD and the enzyme that hold the TTD more rigidly in place.

83 bust than methods in which the constraint is rigidly incorporated, such as hybrid linear analysis, wh

84 Here we show that these rigidly inserted Cy3/Cy5 chromophores also exhibit two a

85 gy transfer fluorophore pairs that have been rigidly inserted into the backbones of replication fork

86 If these criteria are rigidly interpreted, it may be that, by the time medical

87 The rigidly linear monomers condense to form extended solids

88 h occurs regioselectively at only one of the rigidly linked dendrons.

89 proliferation and effector function are not rigidly linked in T cells.

90 with the observation that the spin-label is rigidly linked to band 3 in a fixed orientation with res

91 t cues, yet increases in beta power were not rigidly linked to cues, movements, or movement suppressi

92 and a central free base porphyrin (H2P)-all rigidly linked to each other-serve as light-harvesting a

93 We conclude that MSTd responses are not rigidly linked to specific stimuli, but rather are trans

94 urements, our data indicate that the MreB is rigidly linked to the cell wall, increasing the mechanic

95 ternal cognitive states because they are not rigidly linked with either specific sensory stimuli or t

96 ymphoma kinase (ALK) inhibitors, designed to rigidly lock an energy-minimized bioactive conformation

97 The polyene chain is rigidly locked into a single, twisted conformation, cons

98 sonance (EPR)-active spin probe that is more rigidly locked to the DNA than any previously reported,

99 sFRP1/5 and Dkk3 levels are rigidly maintained via autorepressive and cross-repressi

100 Stable fragments rarely coincide with rigidly moving fragments and often disagree with the CAT

101 of protein fragments and compare stable and rigidly moving fragments.

102 ce structure and requires that the atoms fit rigidly on that lattice.

103 proximately 0.16 and 0.25 and also show that rigidly ordered phases seem to disappear around chi(chol

104 the naked mole-rat, a species with the most rigidly organized reproductive hierarchy among mammals.

105 Aergic postsynaptic specializations are less rigidly organized than glutamatergic postsynaptic densit

106 The acquired knowledge was rigidly organized, and performance collapsed when the ta

107 Thus, what E.P. learned was rigidly organized, unavailable as conscious knowledge, a

108 orce its conjugated diene double bonds to be rigidly oriented 32 degrees out-of-plane.

109 n the power stroke (weak-binding states) and rigidly oriented later in the power stroke (strong-bindi

110 indicate that bound alpha-neurotoxin is not rigidly oriented on the surface of AChBP but rather exhi

111 lative orientation of the two domains is not rigidly oriented with respect to one another in solution

112 protein or possibly because the core is not rigidly packed in wild-type PLB.

113 For the rigidly packed residues, the average RMSD to the mean st

114 e trifluoromethyl ketones by incorporating a rigidly positioned carbonyl group to participate in a hy

115 hrough a structural change where EDTA-U24 is rigidly positioned out of the helix and cannot get acces

116 that like GFP the tetrameric form of HAL is rigidly preorganized for cyclization.

117 However, sustained gene transcription is rigidly prevented to avoid lethal STING-dependent proinf

118 Furthermore, far from being rigidly programmed by the original activating stimulus,

119 cells to quantitatively respond to substrate rigidly provides an intriguing new model for mechanobiol

120 ely automatic software package to normalize, rigidly register and elastically match serial whole-body

121 .5% for unregistered, rigidly registered and rigidly registered + matched images, respectively.

122 of 73.4%, 78.7% and 91.5% for unregistered, rigidly registered and rigidly registered + matched imag

123 Non-rigidly registered images of a silica-supported platinum

124 st overall reproducibility was obtained with rigidly registered phase 1 and phase 2 images, with with

125 Preprocedural FDG PET scans were rigidly registered through a semiautomatic method to int

126 Patient images were rigidly registered together, and intratumor tracer uptak

127 findings suggest that substrate is held more rigidly relative to the oxidizing species at low tempera

128 rpyridyl-palladium-ligand (terpy-Pd-L) units rigidly separated by about 7 A has been investigated for

129 Formerly rigidly separated research efforts in academic instituti

130 nlike motoneurons, may not yet have acquired rigidly specified identities and/or the ability to recog

131 ckly stopped, suggesting that Z rings became rigidly stabilized in the absence of GTP hydrolysis.

132 nsport is less discriminate than in the more rigidly stacked DNA double crossover assemblies.

133 Syntactic CCGs in the field (a) were more rigidly stereotyped than ordinary syntactic CCGs in the

134 state in the early steps of activation to a rigidly structured open state.

135 reas in the inactive state the water is more rigidly structured.

136 le, site-specific modified base containing a rigidly tethered, electron paramagnetic resonance active

137 ated with viral nucleoprotein complexes more rigidly than mature capsid and NC.

138 s work suggesting that the 5'-T is held more rigidly than the 3'-T.

139 s a self-assembling oligomer, A(n), is fused rigidly to one molecule of protein B, which forms anothe

140 4-amino-4-carboxylic acid), which is coupled rigidly to the alpha-carbon, providing direct detection

141 that a model in which CTD units are attached rigidly to the parallel beta-sheet core is consistent wi

142 s of 25 +/- 4 water molecules that are bound rigidly to the protein for a time long compared with the

143 Fab 5F10 fixes the B domain rigidly to the surface of the virus, blocking exposure o

144 stance between the structures (appropriately rigidly transformed).

145 e largest structural variations, not the one rigidly trapped in a deep, but narrow, conformational en

146 The upper peak overlapped and displaced rigidly with the crural sling, while the distal peak sep

147 2.7 ns) than it could if it were interacting rigidly with the iSH2 domain.

148 ongitudinal asymmetries that corotate nearly rigidly with the planet.