ライフサイエンスコーパス: rigorously

1 t only validated numerically but also proven rigorously.

2 sian countries but have never been evaluated rigorously.

3 ction adenocarcinomas has not been evaluated rigorously.

4 ted, but this assumption has not been tested rigorously.

5 d confounding factors have not been examined rigorously.

6 ng these ecosystems have not been quantified rigorously.

7 ptors, such as deprotonation energies (DPE), rigorously account for Bronsted acid strength for cataly

8 This beta mechanism rigorously accounted for the beta event profiles; severa

9 To rigorously address this question, we employed Wt1(CreERT

10 n was clarity of presentation, and the least rigorously addressed domain was applicability of guideli

11 rlo sampling) provide a generalizable way of rigorously addressing parameter inference and identifiab

12 date there have been no longer-term studies rigorously addressing whether migratory management is de

13 ors (ICDs) and evaluate associations between rigorously adjudicated AT/AF and predefined clinical eve

14 Rigorously adjudicated electrogram (EGM) data were corre

15 In the RATE Registry, rigorously adjudicated short episodes of AT/AF, as defin

16 The main cellular properties are not rigorously affected.

17 C NMR spectroscopy and MALDI-TOF MS showed a rigorously alternating sequence.

18 ctive oxygen species has made it possible to rigorously analyze these reactive species in biological

19 We present the approach rigorously and discuss the parametrization of the model

20 x experiments to investigate this hypothesis rigorously and explore the determinants of f o.

21 usion that aesthetic response can be studied rigorously and meaningfully within the framework of scie

22 se can be obtained only by dehydration under rigorously anhydrous conditions, resulting in a microcry

23 We present RADAR--a rigorously annotated database of A-to-I RNA editing.

24 ons but remarkably, these data have not been rigorously applied to the understanding of the time depe

25 ay, and lung-protective ventilation was more rigorously applied.

26 ts on activity, which hinders our ability to rigorously apply activity data to answer ecological and

27 Large populations are needed to rigorously assess atypical patterns, which, even in neur

28 Here, we use statistical simulations to rigorously assess how to optimize annotation accuracy an

29 To more rigorously assess RECCES-Rosetta, we carried out four bl

30 r studies on larger cohorts are essential to rigorously assess the effectiveness and robustness of th

31 ng of statistical methodology is required to rigorously assess the incremental value of novel biomark

32 The aim of this study was to rigorously assess the potential for biased agonism in th

33 We rigorously assess the utility of predicted contacts for

34 nting in child development, we developed and rigorously assessed a family-based training program desi

35 unction and processing speed, which were not rigorously assessed in this study.

36 hese meta-analyses have merged patients with rigorously assessed mood disorders with major depressive

37 nd double-lung transplantation have not been rigorously assessed since the allocation of donor lungs

38 We rigorously assessed the quality of contigs and scaffolds

39 of vulnerable children, but few studies have rigorously assessed their effectiveness in sub-Saharan A

40 of differential gene expression has not been rigorously assessed using a range of chemical treatment

41 on of monocytes and macrophages has not been rigorously assessed with assays comparable to those used

42 equency in the NET population has never been rigorously assessed, nor has its relationship to present

43 rdiovascular disease (CVD) risk has not been rigorously assessed.

44 adigm for science education but has not been rigorously assessed.

45 ve blood culture bottles (BCBs) has not been rigorously assessed.

46 pse and structural MRI measures has not been rigorously assessed.

47 ollow-up (LTFU) on reengagement has not been rigorously assessed.

48 toring in improving the outcome has not been rigorously assessed.

49 in the acute emergency context has not been rigorously assessed.

50 However, its efficacy has not been rigorously assessed.

51 nd their role as latent reservoirs have been rigorously assessed; however, the frequency of productiv

52 ans that SABRE under these conditions cannot rigorously be referred to as a non-hydrogenative parahyd

53 This reductionistic exercise has rigorously been recapitulated recently with two vertebra

54 ence many-electron energies that are used to rigorously benchmark the standard hierarchy of quantum-c

55 We have rigorously benchmarked our automated methods to ensure t

56 We then test and confirm this hypothesis rigorously by analyzing landings when the apparent rate

57 its impact on localization can be determined rigorously by solving one special boundary problem.

58 with a tetrabutylammonium countercation, is rigorously C3-symmetric featuring intracore distances of

59 tworks, there is, as yet, no method that can rigorously calculate the free energy to bind the entire

60 platform, at a single site, using a panel of rigorously calibrated, qualified, high-throughput, multi

61 In serial adoptive transfers that rigorously challenge self-renewal, E47(het)p21(het) LT-H

62 In this study, we rigorously characterized the plasticity in materials com

63 c utility of microRNA data have not yet been rigorously characterized.

64 t model with the electromagnetic model which rigorously characterizes the electro-optical effects.

65 nition of MSCs and discuss the importance of rigorously characterizing their stem cell activity.

66 e learning method, a decision tree, that can rigorously classify sequences.

67 uate number of seizures for investigators to rigorously compare algorithms and results.

68 To rigorously compare models, we use an evidence-based stat

69 ial fibrillation (AF) and race has only been rigorously compared in population-based studies that dic

70 ce and linkage methods and have not yet been rigorously compared.

71 rt due to the computational cost required to rigorously compute P -values.

72 but methylation landscapes have not yet been rigorously computed.

73 as observed when the analysis was limited to rigorously conducted and well-controlled studies.

74 However, the highest-quality evidence from rigorously conducted randomized clinical trials remains

75 yielded by the systems-biology analysis were rigorously confirmed by QRT-PCR and immunohistology.

76 redicted by theoretical models has yet to be rigorously confirmed by well constrained (radioisotopica

77 cervix and vulva, and their correlation with rigorously confirmed cervical disease status, are sparse

78 We compare model outputs to proxy data, and rigorously constrain model parameters using Bayesian inv

79 ist clinic-based studies that were unable to rigorously control for unmeasured environmental and gene

80 complex, next-generation nanomaterials with rigorously controlled architectures and interfaces.

81 t of PrP(C) on polymerization of Abeta under rigorously controlled conditions in which Abeta converts

82 he influence of hormones on disease requires rigorously controlled human population studies, as well

83 at, barley, faba bean and potato produced in rigorously controlled long-term field trials comprising

84 with few effective treatments and a lack of rigorously controlled trials.

85 Growing plant cells need to rigorously coordinate external signals with internal pro

86 and experimental data that this bias can be rigorously corrected by weighing the contribution by eac

87 urrently, there are few existing methods for rigorously decontaminating eukaryotic assemblies.

88 aracterize foulants on membrane surfaces and rigorously deduce their contributions to physically irre

89 rphous materials is the fact that one cannot rigorously define the phonon velocities for non-propagat

90 itself becomes questionable when one cannot rigorously define the phonon velocities.

91 ally, QC metrics implemented in QuaMeter are rigorously defined and tested.

92 ry pseudotumor cerebri syndrome (n = 16), as rigorously defined by recently revised diagnostic criter

93 hat criteria should the NIH use to determine rigorously defined exceptions to the future proposal req

94 Herein, we demonstrate that even the most rigorously defined HSCs can be separated into functional

95 articles, but these forces have been neither rigorously defined nor quantified in generic systems.

96 ted mutational analysis of 194 patients with rigorously defined s-AML or t-AML and 105 unselected AML

97 sons of human and swine influenza viruses to rigorously demonstrate that human influenza virus evolve

98 standing of these unusual antiporters and to rigorously demonstrate that they function as secondary a

99 ials properties, these effects have not been rigorously demonstrated previously.

100 ure is suitable for geometry optimization is rigorously demonstrated.

101 le statistical mechanics models, are used to rigorously derive the continuum equations governing visc

102 analysis method is realized by employing the rigorously-derived Relative Entropy Rate, which is direc

103 A rigorously designed and executed sexual assault resistan

104 Rigorously designed clinical trials are needed to confir

105 Rigorously designed longitudinal studies are needed to e

106 Rigorously designed PIR promotes global learning and loc

107 This rigorously designed set of QIs should facilitate measuri

108 Results from larger rigorously designed studies applicable to all crying inf

109 on requires reliable species assessments and rigorously designed surveys.

110 Ongoing randomized studies will help to more rigorously determine the efficacy of flow diversion.

111 rts and for data sharing practices should be rigorously developed and adopted for all types of health

112 We rigorously developed, pilot tested, and analyzed a direc

113 Rigorously differing solar cell structures as well as in

114 creased total ROS and superoxide levels, and rigorously diminished the number of vital and metabolic

115 4 pairs of monozygotic twins (mean age 51.2) rigorously discordant for a lifetime history of MD.

116 Our experimental design allows us to rigorously distinguish altruism from preferences regardi

117 ated, but this fact has seldom been modelled rigorously due to the uneven spacing; (ii) it is practic

118 Model quantum chemistry calculations that rigorously enforce these constraints show that the inter

119 mical connectivity of the cross-link was not rigorously established.

120 cture and properties of this lesion were not rigorously established.

121 developmental data, and has wide utility in rigorously establishing timelines for GRN evolution.

122 k anatomical connections in the mouse brain, rigorously estimable down to the biological limit of a s

123 However, there is an urgent need to rigorously estimate actual mortality rates and quantify

124 ating public health problem, it has not been rigorously estimated within a Canadian context.

125 formation from multiple statistical tests to rigorously evaluate a single overarching hypothesis.

126 Continued research is needed to rigorously evaluate effectiveness, assess costs, and car

127 Rather, we must design and rigorously evaluate interventions to halt transmission,

128 etect IBD segments in exome-sequencing data, rigorously evaluate its performance, and apply this meth

129 ening programs is crucial, and continuing to rigorously evaluate outcomes, including PROs, process of

130 Our objective was to rigorously evaluate the impact of an antimicrobial stewa

131 earch agenda in this area that are needed to rigorously evaluate this hypothesis.

132 Compounds were rigorously evaluated across numerous safety end points a

133 en daunorubicin and doxorubicin has not been rigorously evaluated among survivors of childhood cancer

134 as contributory to risk, but it has not been rigorously evaluated as a principal causal influence.

135 m working memory deficits, but has yet to be rigorously evaluated clinically.

136 s-based stress reduction (MBSR) has not been rigorously evaluated for young and middle-aged adults wi

137 aternity leave on infant health has not been rigorously evaluated in low- and middle-income countries

138 This association has not been rigorously evaluated in other races or ethnicities, in w

139 sympathetic function has not previously been rigorously evaluated in PTSD patients.

140 reclinical hypotheses, which then have to be rigorously evaluated in the clinical setting.

141 kappaBalpha-FLuc bioluminescent reporter, we rigorously evaluated the dynamics of IotakappaBalpha deg

142 nalyzed as an example to show that it can be rigorously evaluated using paired two-sample t-tests.

143 but its ecological performance has not been rigorously evaluated, and restoration has generally fall

144 FR within individuals over time has not been rigorously evaluated, particularly within the normal ran

145 PD-1-directed therapy response has not been rigorously evaluated.

146 o reduce readmissions, but have not yet been rigorously evaluated.

147 f nicotine on brain eCB levels have not been rigorously evaluated.

148 , and polysomnographic findings has not been rigorously evaluated.

149 iveness with or without support has not been rigorously evaluated.

150 uence of these factors on power has not been rigorously evaluated.

151 r vessel, but its effectiveness has not been rigorously evaluated.

152 he primary aim is to develop a framework for rigorously evaluating interventions in AON and to assess

153 In the current study, we rigorously examine the hypothesis that these sperm miRs

154 orphisms and novel statistical approaches to rigorously examine time-series data for signs of various

155 owever, previous studies have been unable to rigorously examine whether confounding factors cause the

156 rtality among persons with ASD have not been rigorously examined in large, population-based studies.

157 e factors most predictive of GR function, we rigorously examined the relationship between in vitro GR

158 No special precautions to rigorously exclude water are required.

159 open to atmosphere, and without the need to rigorously exclude water, thus representing an operation

160 longer prospective follow-up and should more rigorously explore risk factors for a negative donor out

161 tion procedure thus provides a means to more rigorously explore the biology of ncRNA species in mycob

162 To rigorously explore the function of ALRs, we generated mi

163 Here we sought to rigorously explore this hypothesis.

164 differ in populations, but few studies have rigorously explored this variability.We tested the hypot

165 used endogenously in vivo is only now being rigorously explored using unbiased genome-scale approach

166 ch to the best of our knowledge has not been rigorously explored.

167 Cyclic voltammetry on rigorously Fe-free Ni(OH)2/NiOOH reveals new Ni redox fe

168 ize for which the method was optimized, were rigorously followed up and confirmed with PCR-based inve

169 odel Kalman filter that allows us to account rigorously for additional contributions to SL changes an

170 This phenomenon is demonstrated rigorously for the two-pattern Gaussian Hopfield model.

171 urther research is needed before any new and rigorously founded recommendations can be made.

172 his approach provides a well-constrained and rigorously grounded method for determining the number of

173 These stable, rigorously homogenous trimers have antigenic properties

174 ocity-based devices have not been studied as rigorously; however, the majority of studies included in

175 mouse habenula to subnuclei, which had been rigorously identified by several criteria in the rat.

176 py on connective tissue and in muscle fibres rigorously identified for sub-type.

177 hus, genome-scale systems biology approaches rigorously identify a functional core proteome needed to

178 umans with allogeneic cardiac stem cell in a rigorously imaging-based selected group of acute myocard

179 contact--are difficult to test or quantitate rigorously in eukaryotic cells.

180 an outline of how speciation can be studied rigorously, including novel genetic/genomic developments

181 ll molecule agonists and antagonists to more rigorously interrogate the apelin receptor system.

182 h as the one described here are necessary to rigorously investigate NO* stress in microbes.

183 prophylaxis trial provided an opportunity to rigorously investigate these responses in a case-control

184 (AC and DC) to changes in haemorheology were rigorously investigated in an in vitro experimental setu

185 To date, this idea has not been rigorously investigated in patients with schizophrenia.

186 tor neuron degeneration in SBMA has not been rigorously investigated.

187 pacts under natural conditions have not been rigorously investigated.

188 The source of these stores has not been rigorously investigated.

189 ngle gene, but this expectation has not been rigorously investigated.

190 be 'unconscious,' and provide a platform for rigorously investigating unconscious perception in futur

191 The model also rigorously justifies a similar set of relationships, rec

192 ion [UO(2)](2+) in which the oxo groups are rigorously linear and inert.

193 Each metal center is monovalent, rigorously linear, and two-coordinate.

194 While several chemoreceptors were rigorously linked to specific pathways in a series of ex

195 al lineP4(dma)9 phosphazene superbase is now rigorously linked to the scale.

196 layer dependent properties have been studied rigorously, little attention has been paid to the format

197 The sanctity of the cytosolic compartment is rigorously maintained by a number of innate immune mecha

198 Fluidity and a rigorously maintained spacing result in long-range-order

199 oton imaging and a unique analysis method to rigorously measure and track the size and location of ax

200 gence in higher order structure has not been rigorously measured across the mammalian genome, and unt

201 random field (HMRF) based Bayesian method to rigorously model interaction probabilities in the two-di

202 more, through advanced theory, we succeed in rigorously modeling multiscale electron and nuclear quan

203 ensemble sampling in Rosetta) framework that rigorously models conformational entropy, predicts previ

204 observationally based analytical method for rigorously partitioning measured absorption aerosol opti

205 f SubC acetylcholine receptors) has not been rigorously performed.

206 lidated, broadly accessible database that is rigorously phenotyped; a parallel, linkable biorepositor

207 novel XPCI systems, a numerical framework to rigorously predict the performance of a clinical XPCI sy

208 ent algorithms to minimize search times, and rigorously predicts off-target binding of single-guide R

209 Second, in considering how to more rigorously process these data and interpret them using m

210 Valve leaflet formation is a rigorously programmed process consisting of endocardial

211 k' theory for directed tree networks, and we rigorously prove that one node can control a set of targ

212 We rigorously proved the correctness of the new algorithm a

213 Since this has not been rigorously proven in ICU patients, we will study the eff

214 trolyte impurities if the electrolyte is not rigorously purified.

215 sed the ecological causes or consequences of rigorously quantified phytochemical diversity across tax

216 discerned from SAD patterns has not yet been rigorously quantified.

217 reasonably well understood but have not been rigorously quantified.

218 romise, there have been few opportunities to rigorously quantify the ability of these nonstate, marke

219 a brief guide to the mathematical ideas that rigorously quantify the notion of extracting meaning fro

220 ing sequencing repertoires, with the goal of rigorously quantifying differences in V, D, and J gene s

221 respecting the predictions of the models and rigorously quantifying the confidence associated with th

222 yet may contribute to neuropathology if not rigorously regulated.

223 criptor for certain molecular vibrations and rigorously relate errors in frequencies to errors in ads

224 We hypothesized that by rigorously restricting the biodistribution of immunother

225 ngs and the inability of previous studies to rigorously rule out confounding factors.

226 This possibility is not rigorously ruled out by the available data, so it remain

227 The EEG was recorded from 57 rigorously screened adolescents (12 to 17 years of age;

228 Patients should be rigorously screened for certain ocular and systemic cond

229 elect, a comprehensive analysis pipeline for rigorously selecting screen hits and identifying functio

230 commonly used linear noise approximation, we rigorously show that, in the limit of slow promoter dyna

231 progression events (in 21% of patients) for rigorously staged patients.

232 r debulking plaque with atherectomy are less rigorously studied and have niche roles.

233 and extent of this phenomenon have not been rigorously studied and, most importantly, there is no cu

234 this period on risk factors has not been as rigorously studied as the postoperative period.

235 Although these algorithms have been rigorously studied for in vitro conditions, which are gr

236 To date, little quantitative analysis has rigorously studied these topics.

237 roplets placed on such surfaces has not been rigorously studied.

238 ant human C1 esterase inhibitor has not been rigorously studied.

239 er of sex determination mechanisms have been rigorously studied.

240 nt for these conditions, but it has not been rigorously studied.

241 erlying this beneficial effect have not been rigorously studied.

242 ading to beta-cell dysfunction have not been rigorously studied.

243 ects of processing and storage have not been rigorously studied.

244 s a lower-cost alternative but have not been rigorously studied.

245 research methods are urgently needed to more rigorously summarize and evaluate the evidence, but mult

246 along the nanotube surface, thus controlling rigorously SWNT-electron acceptor stoichiometry and orga

247 sciences and humanities working together to rigorously test hypotheses about general rules that may

248 /EZH2 are now in human testing, we wished to rigorously test such an inhibitor in a primary resting T

249 In order to rigorously test the accuracy of both structural models,

250 unbiased manipulative field experiments that rigorously test the effects of individual traits on comm

251 However, it is not always possible to rigorously test these hypotheses in vivo We applied in v

252 present two studies using virtual reality to rigorously test this hypothesis.

253 However, only participant-level analyses can rigorously test whether the treatment effect is influenc

254 ctuations, but these models are difficult to rigorously test.

255 his, such new strategies are currently being rigorously tested and validated in preclinical studies b

256 28/30, 93%) of the instruments have not been rigorously tested for validity or reliability.

257 tions is questionable, as they have not been rigorously tested for virulence in vivo in comparison wi

258 Propofol and dexmedetomidine have not been rigorously tested in comparative studies of drug withdra

259 is problem has attracted enormous attention, rigorously tested interventions outside artificial labor

260 ching of various common fluorophores, and we rigorously tested more than a dozen examples.

261 Yet existing, rigorously tested neurodegenerative disease biomarkers a

262 We then rigorously tested the sensitivity and specificity of the

263 MTB genes within this regulatory network was rigorously tested using two independently generated data

264 ts performance in CNV detection has not been rigorously tested.

265 This assumption, however, has not been rigorously tested.

266 the cytosol), this assumption has never been rigorously tested.

267 g performance measures before they have been rigorously tested.

268 nto spindle MTs, but this model has not been rigorously tested.

269 widespread dispersal ability has never been rigorously tested.

270 These hypotheses have not previously been rigorously tested.

271 function; however, neither strategy has been rigorously tested.

272 onal cell motility, this notion has not been rigorously tested.

273 ine conserved in bacteria) have not yet been rigorously tested.

274 his theory and its assumptions have not been rigorously tested.

275 Yet this paradigm has not been rigorously tested.

276 Peer mentoring has not been rigorously tested.

277 orphology of brain microvasculature far more rigorously than what is possible using semi-quantitative

278 We show rigorously that in a light-matter wave-mixing process in

279 s of the Markov chain, we would like to show rigorously that the presented state is an outlier with r

280 Specifically, we show rigorously that, when the secondary structure of a polym

281 nsformation, we prove a theorem to determine rigorously the control efficacy of the network and to id

282 We suggest how to evaluate rigorously the environmental effects of GM crops in the

283 ions that allow analyzing and comparing more rigorously the performances of existing catalysts when t

284 lish and Spanish, and interviewers have been rigorously trained.

285 , lacked both the data and the tools to more rigorously understand the patterning of multiple interac

286 d on this model, yet its predictions are not rigorously understood.

287 However, this issue could not be addressed rigorously until late in the 20th century.

288 We test the procedure rigorously using simulated trajectories for which the un

289 s of mass media and epidemiology: to measure rigorously, using a cluster-randomised design, how many

290 re summarized in best practices for building rigorously validated and externally predictive QSAR mode

291 emonstrates a practical approach to obtain a rigorously validated atomic resolution electron cryo-mic

292 Among the genes in the network, we rigorously validated candidates using functional CFTR ma

293 Here, using rigorously validated competitive ELISAs with engineered

294 of suitable measurement devices and lack of rigorously validated protein panels.

295 RNAsnp and SNPfold, perform best on the most rigorously validated subsets of the benchmark data.

296 een proposed, to date, few of them have been rigorously validated through observational and experimen

297 e combinations with the given phenotype, and rigorously validates the results using a series of unbia

298 ed resistance, underscores the importance of rigorously validating quantitative biomarkers of treatme

299 cross-linked complex is immunoprecipitated, rigorously washed, and then digested into peptides while

300 iatric nephrolithiasis have not been studied rigorously, which contributes to the paucity of data in