ライフサイエンスコーパス: ring-opening

1 n the three-membered ring boosted the TOF of ring opening.

2 ehydrogenation, reductive debromination, and ring opening.

3 ecules by the significant size increase upon ring opening.

4 Cdc7 phosphorylation of Mcm2 promotes Mcm2-7 ring opening.

5 re to 1,2-cyclobutadiene followed by thermal ring opening.

6 iduronate components, reversible by lactone ring opening.

7 enes upon acid-promoted cyclopropyl carbinol ring opening.

8 uggesting a potential mechanism for helicase ring opening.

9 tion of deoxyguanosine followed by imidazole ring opening.

10 -sigmatropic rearrangement, and heterocyclic ring opening.

11 onalized systems via solvolytic nucleophilic ring opening.

12 e attached by electrophilic cyclopropanation-ring opening.

13 ,2-dimethylenecyclopentane via electrocyclic ring-opening.

14 -DABCO salts with nucleophiles, resulting in ring-opening.

15 ted imines that alkylate DNA by cyclopropane ring opening (2 --> 3).

16 Furthermore, the selective imidazolidine ring opening accompanied by CH2 extrusion yielded tetra-

17 The reversible ring-opening addition and fragmentation reaction of p-cr

18 n-1-yl)benzene give access to functionalized ring-opening alkyne metathesis polymerization (ROAMP) in

19 ve the propagating molybdenum species in the ring-opening alkyne metathesis polymerization (ROAMP) of

20 ships reveal that the initiation step of the ring-opening alkyne metathesis polymerization of 5,6,11,

21 hyl (R = Et) substituent initiate the living ring-opening alkyne metathesis polymerization of the str

22 The ring-opening alkyne metathesis polymerization with 1 has

23 nnelation results in increased retro-Bergman ring opening, allowing C(1)-C(5) cyclization to become a

24 mium, cobalt, and aluminum catalysts for the ring-opening alternating copolymerization of epoxides wi

25 + 2]-cycloaddition followed by electrocyclic ring opening and a terminating [4 + 2]-type cycloadditio

26 on and elaborated via regioselective epoxide-ring opening and diastereoselective bromoetherification.

27 xide with the diene, in which stereospecific ring opening and formation of the two new C-C bonds occu

28 on was developed, allowing for the isoxazole ring opening and global deprotection to be achieved in o

29 f iron-sulfur cluster cofactors in reductive ring opening and hydroxy-group elimination.

30 alculations and showed that taurine-driven E-ring opening and increasing negative charge generally en

31 leic anhydride underwent selective anhydride ring opening and intersected an established precursor in

32 -pot, sequential protocol using an aziridine ring opening and intramolecular nucleophilic aromatic su

33 The chiral structure has a low barrier to ring opening and may best explain results on enyne photo

34 vities of LTA4H, alternating between epoxide ring opening and peptide bond hydrolysis, assisted by E2

35 etalated isoxazoline intermediate results in ring opening and the formation of a ketene intermediate.

36 yst on the regioselectivities of the epoxide ring-opening and acylation steps.

37 d through an initial cyclization followed by ring-opening and concurrent C6F5-group migration.

38 Finally, examples of oxetane derivatives in ring-opening and ring-expansion reactions are described.

39 ormal [2+2] cycloaddition, 4pi-electrocyclic ring opening, and 6pi-electrocyclic ring-closing events,

40 These include ring expansion, ring opening, and C-2 functionalization.

41 cycloaromatization, radical cyclization and ring opening, and SN 2.

42 essential for downstream aryl modification, ring opening, and subsequent assimilation of these compo

43 The mechanism of ion-pairing, ring-opening, and catalyst deactivation have been studie

44 diarylpyrans subsequent to fluoride-induced ring opening are remarkably high (330-480 nm), and are u

45 Both the cyclopropanation and subsequent ring-opening are shown to be stereospecific.

46 and isotope labeling studies suggest epoxide ring opening as the turnover limiting step in our propos

47 ry few examples able to undergo nucleophilic ring opening at a quaternary carbon with complete invers

48 ne hydrobromide, enabled their regiospecific ring-opening at C6 position by organometallic nucleophil

49 lization indicative of a large retro-Bergman ring opening barrier (k2 > k-1).

50 t to Dimroth rearrangement which consists of ring opening, bond rotation, and ring closure.

51 osition of the aziridine by way of aziridine ring opening by Ni (inversion), transmetalation (retenti

52 o effect regio- and stereospecific aziridine ring opening by oxygen, halogen, sulfur, and nitrogen nu

53 ential reactions with a nucleophile (epoxide ring-opening by chloride) and an electrophile (O-acylati

54 rted herein is an exceptional chemoselective ring-opening/C(sp(3) )-C(sp(3) ) bond formation in the c

55 Typical ring-opening catalysts are subject to a trade-off betwee

56 plays no role in the conventional cascade of ring opening/closing.

57 heoretical calculations support a bimetallic ring-opening/closing pathway over a concerted oxidative

58 ostulated that His-390 is closely related to ring opening/closure by transferring a proton between th

59 opening polymerization (ROP) of lactones and ring-opening copolymerization (ROCOP) of epoxides, anhyd

60 The organocatalytic anionic ring-opening copolymerization of 2-alkyl-2-oxo-1,3,2-dio

61 ring-opening polymerization of lactones and ring-opening copolymerization of epoxides/anhydrides.

62 The ring-opening copolymerization of maleic anhydride and pr

63 l glycidate carbonate)s are obtained via the ring-opening copolymerization of rac-/(R)-benzyl glycida

64 In addition, imidazolidine ring opening coupled with SO2 extrusion provided synthet

65 icable Ru-catalyzed protocol for Z-selective ring-opening/cross-metathesis (ROCM) is disclosed.

66 e featured processes are an enantioselective ring-opening/cross-metathesis promoted by a Mo monoarylo

67 eoselectivity (de, ee up to >99%) via domino ring opening cyclization (DROC) of activated aziridines

68 A Bi(OTf)3-catalyzed ring-opening cyclization of (hetero)aryl cyclopropyl car

69 Lewis acid catalyzed domino ring-opening cyclization of activated aziridines with ar

70 atalyst, alkenyl cyclopropyl ketones undergo ring-opening cyclization to form six-membered cyclic oxy

71 ich subsequently undergoes an intramolecular ring-opening cyclization.

72 By exploiting the ring-opening-cyclization reaction mechanism, we have des

73 We also highlight the method in a tandem ring-opening/debenzylation method for the generation of

74 C2 methylation in the absence of cyclopropyl ring opening, disfavoring mechanisms that involve unpair

75 With ring-opening disulfide-exchange polymerization, we show

76 nediimides were grown on indium tin oxide by ring-opening disulfide-exchange polymerization.

77 p, with C-C bond scission instead leading to ring opening, efficient functionalization, and high SOA

78 can be circumvented due to the fast thermal ring-opening except for pH values below 3.

79 as well as compounds resulting from epoxide ring opening, exemplified by epoxydiol.

80 n electrocyclic pathway via an electrocyclic ring opening followed by a ring flip and a subsequent el

81 es afforded cyclopentene derivatives through ring opening followed by cyclization (vinylcyclopropane-

82 s, where the aldol condensation, cyclopropyl ring opening followed by cyclization took place in a sin

83 -1,3-diene derivatives stereoselectively via ring opening followed by proton elimination.

84 and offer the opportunity for strain-induced ring-opening following the initial reaction of the alkyn

85 mperature that is required to facilitate the ring opening (from 50 degrees C to 180 degrees C) and th

86 1,6-Anhydro ring opening gave suitable substrates for efficient synt

87 The resulting cyclopropanone ring openings gave unsaturated aldehydes.

88 e metabolite teriflunomide through isoxazole ring opening has been monitored in vitro using steady st

89 sformation involves an oxa-6pi electrocyclic ring-opening/hetero-Diels-Alder pericyclic cascade.

90 n reactions followed by fully regioselective ring opening/Hofmann rearrangement/nitrogen protection,

91 itor that undergoes reversible, pH-sensitive ring-opening hydrolysis.

92 Acid or ammonium - catalyzed ring-opening IEPOX chemistry as well as sulfate-driven A

93 -Bromosuccinimide-mediated 4,6-O-benzylidene ring opening in 8-azido-3,6-dioxaoctyl 4,6-O-benzylidene

94 dates, switching off and on the nucleophilic ring-opening in a controlled manner.

95 er subsequent to C-H homolysis competes with ring-opening in the processing of the C2 radical interme

96 nol adducts were produced firstly by epoxide-ring opening initiated by the attack of one phenolic hyd

97 ug's ionization state, membrane binding, and ring-opening interconversion kinetics.

98 cyclopropyl carbinyl cations, which undergo ring opening, intramolecular trapping by the neighboring

99 The conrotatory ring-opening is torquoselective, and the transition stat

100 We propose that a novel kind of ring-opening lyase is involved in the further catabolic

101 polymerized through a radical pathway via a ring-opening mechanism (addition-fragmentation process),

102 tioned leaving group that could facilitate a ring-opening mechanism, leading to inactivation of GABA-

103 The observed Z-selectivity for the ring-opening metathesis (ROM) of COE is due to the large

104 ctively underwent single monomer addition in ring-opening metathesis but readily underwent alternatin

105 gineer an iterative one-pot cross metathesis-ring-opening metathesis polymerization (CM-ROMP) strateg

106 n industrially important molecular ruthenium ring-opening metathesis polymerization (ROMP) catalyst u

107 )) and triazole phosphates (Si-OTP(n)) using ring-opening metathesis polymerization (ROMP) for use as

108 We have developed a method to achieve ring-opening metathesis polymerization (ROMP) mediated b

109 ontrol over bottlebrush polymer synthesis by ring-opening metathesis polymerization (ROMP) of macromo

110 The rate of living ring-opening metathesis polymerization (ROMP) of N-hexyl

111 Metal-free ring-opening metathesis polymerization (ROMP) utilizes o

112 ll-Z polynorbornene and polynorbornadiene by ring-opening metathesis polymerization (ROMP) with contr

113 The microstructures of polymers produced by ring-opening metathesis polymerization (ROMP) with cyclo

114 ing AB copolymers have been prepared through ring-opening metathesis polymerization (ROMP) with Mo(NR

115 om-transfer radical polymerization (ATRP) or ring-opening metathesis polymerization (ROMP).

116 tailored architectures via grafting-through ring-opening metathesis polymerization (ROMP).

117 istribution of grafts in polymers via living ring-opening metathesis polymerization (ROMP).

118 igins of regio- and stereoselectivity in the ring-opening metathesis polymerization of 3-substituted

119 polynorbornene bearing pendant NTAs made by ring-opening metathesis polymerization was also synthesi

120 metathesis but readily underwent alternating ring-opening metathesis polymerization with low-strain c

121 Focusing on ring-opening metathesis polymerization, we found that th

122 ereoselective epoxidation and regioselective ring-opening methods were developed for the synthesis of

123 ion, which is initiated via isobenzofuranone ring opening of 2 in a Michael-type reaction.

124 tion/intramolecular cyclization/carbohydrate-ring opening of 2-haloenones with 1,3-dicarbonyl compoun

125 ry is used to induce the disrotatory outward ring opening of a cis-dialkyl substituted syn-chloro-gem

126 Ring opening of a P-B-containing cyclobutene isostere pr

127 hyl radical generated from Ti (III) mediated ring opening of a terminal epoxy ring tethered to a bute

128 oselective desymmetrization catalysts in the ring opening of a variety of cyclic anhydrides.

129 -b]indoles via Lewis acid-catalyzed SN2-type ring opening of activated aziridines with indoles having

130 ar products formed with 100% selectivity for ring opening of all reactants catalyzed by the Rh NP.

131 rtaken to examine the scope of the reductive ring opening of aziridine-2-carboxylates with samarium d

132 The reactions involve a regiospecific ring opening of aziridines with benzimidazoles to give b

133 ening, we hypothesized that taurine-driven E-ring opening of bacteriochlorophyll derivatives and net-

134 elerating the symmetry forbidden disrotatory ring opening of benzocyclobutene (BCB).

135 The copper-catalyzed ring opening of chiral-pool-derived 1,1'-diBoc-2,2'-biaz

136 e ligand-directed beta-C-H arylation and the ring opening of cyclopropanecarboxamides is proposed bas

137 d sp(3) C-H activation/arylation followed by ring opening of cyclopropanecarboxamides, which were ass

138 upported in mesoporous silica, catalyzed the ring opening of cyclopropylbenzene at room temperature u

139 ,3-b]indoles has been developed via SN2-type ring opening of enantiopure N-activated aziridines with

140 interest and the nonscissile mechanochemical ring opening of gem-dichlorocyclopropane mechanophores a

141 r was also observed in the Z form during the ring opening of leflunomide.

142 e readily synthesized through a nucleophilic ring opening of spiro[cyclopropane-1,3'-oxindoles] with

143 tep of this process involves a base-mediated ring opening of the 3-aroylbenzofurans and subsequent Mi

144 into the influence of N-substituents on the ring opening of the aziridinium intermediate indicated d

145 The first step of the ring opening of the epoxide is the rate-determining step

146 ranyl MIDA boronate (24) comprise two steps: ring opening of the epoxide to a carbocation intermediat

147 oxy propenes formed in situ via base-induced ring opening of the epoxide-leads to the syn-selective p

148 aromatic hydroxylation of prephenalenone and ring opening of the gamma-pyrone ring simultaneously.

149 pid single addition and the rate-determining ring opening of the low-strain olefin.

150 namic behavior as a result of the reversible ring opening of the pendant 1,2-dithiolanes.

151 p reduction of acetate groups, and reductive ring opening of the resulting hemiacetal as the key step

152 methylation enables further modification and ring opening of the single-ring aromatics vanillate and

153 olves three cycloadditions and electrocyclic ring opening of the strained Dewar anthracene.

154 ric acid leads to an unprecedented oxidative ring opening of the triptycene scaffold, resulting in a

155 In all cases, S(N)2-type ring opening of these epoxides upon treatment with aqueo

156 zed 1,3-dihydro-2H-benzimidazol-2-ones via a ring opening of thiazolo[3,2-a]benzimidazolium or benzim

157 cted from the general mechanism of oxidative ring openings of imidazoles, likely affecting the bioact

158 Thermal ring openings of the cyclobutenes give (Z,Z)-1,3-diene p

159 theses of 2-alkyl indoles via regioselective ring-opening of 2-(2-haloaryl)-3-alkyl-N-tosylaziridines

160 report the tandem base-promoted elimination/ring-opening of 2-benzyl-1,3-dithianes with subsequent c

161 Contrary to the G2 case, however, the ring-opening of 3MCOE by MAP catalysts prefers a proxima

162 d generation of 2-amidoallyl cations through ring-opening of 4-benzylidene-2-oxazolines with Sc(OTf)3

163 Oxidative cyclopropane ring-opening of 5-substituted 3-azabicyclo[3.1.0]hex-2-e

164 ionalizable appendages has been developed by ring-opening of activated aziridines with 2-hydroxypheny

165 inophosphine oxide diastereomers accessed by ring-opening of an amino alcohol-derived cyclic sulfamid

166 e intramolecular cyclization followed by the ring-opening of an aza-palladium(II) tricyclic intermedi

167 rivatives have also been synthesized via the ring-opening of aziridines with 2-bromobenzyl alcohols a

168 oselective and challenging gold(I)-catalyzed ring-opening of cyclic 1,3-dioxolanes and dioxanes by tr

169 on of butadiene with ethylene, electrocyclic ring-opening of cyclobutene, electrocyclic ring-closing

170 The ring-opening of cyclopropane-1,1-dicarboxylates with vic

171 demonstrated through the catalytic oxidative ring-opening of cyclopropanes for the synthesis of 1,3-f

172 onvenient low-cost method for regioselective ring-opening of donor-acceptor cyclopropanes with the Zn

173 In addition, ring-opening of epoxide by an intermediate comprising mu

174 initiator/chain end to effect the selective ring-opening of lactones and carbonates.

175 ase-transfer catalysis: the enantioselective ring-opening of meso-aziridinium and episulfonium cation

176 ndipitously proceeding through an S(N)2-type ring-opening of N-activated aziridines with 2-bromobenzy

177 The stereospecific ring-opening of O-heterocycles to provide acyclic alcoho

178 en exploited, for the first time, to trigger ring-opening of photochromic diarylbenzo-/naphthopyrans

179 acid catalysis (regioselective methanolysis ring-opening of styrene oxide), oxidative cyclization ca

180 proceeds via a Lewis acid catalyzed SN2-type ring-opening of the activated aziridine followed by a co

181 y in situ ring-expansion (via intramolecular ring-opening of the corresponding aziridinium intermedia

182 ubstitution on the alkene moiety, subsequent ring-opening of the cyclopropane affords either cyclopen

183 Nucleophilic ring-opening of the epoxides with water, alcohols, and H

184 Initially, a stereoselective ring-opening of the key intermediate N-acetylneuraminic

185 irinium ylide to metal-free azirinium ylide, ring-opening of the latter to give a 1,5-diazahexa-1,3,5

186 oach for colorimetric sensing of fluoride by ring-opening of the otherwise photochromic benzo-/naphth

187 Ring opening on the time scale of tens of milliseconds i

188 ls were first prepared in the early 1990s by ring-opening polymerisation (ROP) of silicon-bridged [1]

189 Mw/Mn = 1.05-1.17) were obtained via anionic ring opening polymerization (AROP) with molecular weight

190 Organocatalytic ring opening polymerization (ROP) of eight-membered cycl

191 degradable polymer prepared by the catalyzed ring opening polymerization of lactide.

192 that employs relay metathesis to promote the ring opening polymerization of unstrained macrocyclic st

193 is achieved via a regio- and stereoselective ring opening polymerization to generate multiple glycosi

194 hilic polyoxazoline chain is grafted through ring opening polymerization, possess homogeneous spheric

195 rying initiation sites by the living anionic ring opening polymerization.

196 e of oligomer length, by the organocatalytic ring-opening polymerization (OROP) of 5-membered cyclic

197 Ring-opening polymerization (ROP) is a powerful syntheti

198 Ring-opening polymerization (ROP) of an allyl-substitute

199 zation can be regulated and switched between ring-opening polymerization (ROP) of BBL and CHO/CO2 cop

200 methods for accessing these materials is the ring-opening polymerization (ROP) of cyclic monomers.

201 Here a single switchable catalyst for both ring-opening polymerization (ROP) of lactones and ring-o

202 ntional chemoselectivity to enable the first ring-opening polymerization (ROP) of MBL, thereby produc

203 catalyst to a polymer in the organocatalyzed ring-opening polymerization (ROP) of rac-lactide (rac-LA

204 Iso-selective initiators for the ring-opening polymerization (ROP) of rac-lactide are rar

205 d adduct (PyMA) as an organocatalyst for the ring-opening polymerization (ROP) of the cyclic O-carbox

206 design of complex single-site catalysts for ring-opening polymerization (ROP) to enhance both activi

207 a class of viable monomers which can undergo ring-opening polymerization (ROP) to prepare poly(alpha-

208 Radical ring-opening polymerization (rROP) combines the advantag

209 nation of metal-free organo-catalytic living ring-opening polymerization and post-polymerization chai

210 ation (rROP) combines the advantages of both ring-opening polymerization and radical polymerization,

211 The thermodynamics of the ring-opening polymerization depends sensitively on the h

212 eport the synthesis, reactivity studies, and ring-opening polymerization of a tricarba[3]nickelocenop

213 mide linkages are synthesized by the anionic ring-opening polymerization of an altrose beta-lactam mo

214 erein we report an expedient organocatalytic ring-opening polymerization of cyclic carbonates contain

215 ysis, depolymerization of branched polymers, ring-opening polymerization of cycloalkanes, and other u

216 e and ethylene carbonate, was synthesized by ring-opening polymerization of ethylene carbonate.

217 Ring-opening polymerization of functional monomers has e

218 The ring-opening polymerization of L-lactide mediated by the

219 produced commercially by the metal-catalyzed ring-opening polymerization of lactide.

220 d to prepare block copolyesters by combining ring-opening polymerization of lactones and ring-opening

221 Ring-opening polymerization of lactones is a versatile a

222 The organocatalytic ring-opening polymerization of N-acyl morpholin-2-ones o

223 Synthetic polypeptides from the ring-opening polymerization of N-carboxyanhydrides (NCAs

224 ltaneously fast and selective for the living ring-opening polymerization of several common monomers,

225 ough synthetic cascades of ROAMP followed by ring-opening polymerization of strained epsilon-caprolac

226 Controllable ring-opening polymerization of the heteroleptic tin-brid

227 The thermodynamics and kinetics of ring-opening polymerization of the two dithiolanes were

228 copolymer was synthesized by initiating the ring-opening polymerization of trimethylene carbonate (T

229 Our six-membered cyclic phosphoester ring-opening polymerization strategy is demonstrated, he

230 he strained 3',5'-cyclic monomer can promote ring-opening polymerization to afford the resulting poly

231 avable linker is achieved by organocatalyzed ring-opening polymerization.

232 addition of a thiol initiates the reversible ring-opening polymerizations of dithiolanes in the micel

233 thioureas that catalyses rapid and selective ring-opening polymerizations.

234 adiene concentration, revealed retro-Bergman ring opening predominates over hydrogen atom abstraction

235 An unexpected 2,3-dihydrofuran ring opening process at the C(4)-C(5) bond has been deve

236 istent with a redox-neutral SN2 nucleophilic ring-opening process as opposed to a Pd(II)/Pd(IV) pathw

237 ) chemistry, a novel C-N bond activation and ring-opening process is described for these increasingly

238 This stereospecific ring-opening process was efficiently promoted by a tungs

239 volving a Michael addition-6pi-electrocyclic ring opening-proton transfer and 6pi electrocyclization,

240 otoxic effects in vitro, this ClbS-catalyzed ring-opening provides a means for the bacteria to circum

241 , and increasing force reverses the relative ring opening rates of the two isomers.

242 RAS studies show that the superoxide induced ring opening reaction of PC is determined by the electro

243 hoxytriptycene does not undergo an oxidative ring opening reaction.

244 lfonamide is unprotected, the characteristic ring-opening reaction is completely silenced, which expl

245 apping agent played an important role in the ring-opening reaction kinetics.

246 ovide deeper understanding of the reversible ring-opening reaction mechanism of 1,3-benzoxazine with

247 The ultrafast light-activated electrocyclic ring-opening reaction of 1,3-cyclohexadiene is a fundame

248 se, (2) selective Strecker reaction, and (3) ring-opening reaction of a diastereomeric mixture of a d

249 molecules stochastically generated from the ring-opening reaction of a spiropyran, we provide mechan

250 Only after this light triggers the ring-opening reaction of dithienylethene chromophores at

251 The mechanically accelerated ring-opening reaction of spiropyran to a colored merocya

252 re proved stable under basic conditions, the ring-opening reaction of the furan moiety with hydrazine

253 The ring-opening reaction of trans-2-aroyl-3-styrylcycloprop

254 We report a highly efficient ring-opening reaction of vinylcyclopropanes by boronic a

255 recting effect of the sulfonamide moiety the ring-opening reaction proceeded selectively at the C-3 p

256 reaction could be combined with an aziridine-ring-opening reaction to give highly functionalized alip

257 d diastereoselective chlorinative oxabicycle ring-opening reaction to introduce the challenging alkyl

258 tected indazoles are prone to an undesirable ring-opening reaction to liberate o-aminobenzonitriles.

259 The scope of the aziridine ring-opening reaction was substantially broadened contra

260 rm is irradiated with UV light to induce the ring-opening reaction, one of the highest switching rati

261 macrocycles exhibit stepwise, light-induced, ring-opening reactions (DHA-DHA to DHA-VHF to VHF-VHF; V

262 hout bond breaking or bond formation, namely ring-opening reactions and cis-trans isomerizations, res

263 inal chemistry and its propensity to undergo ring-opening reactions as a synthetic intermediate.

264 the relevance of the protonation step in the ring-opening reactions of 1,3-benzoxazines with thiols i

265 timescale of the experiments, the forbidden ring-opening reactions of benzocyclobutene, gem-difluoro

266 In this work, ring-opening reactions of cyclopropane derivatives under

267 structures for the conrotatory electrocyclic ring-opening reactions of N-substituted 2-azetines were

268 These ring-opening reactions proceed with high regioselectivit

269 ced, which explains that the majority of the ring-opening reactions reported in the literature invoke

270 exane suggests that it may be susceptible to ring-opening reactions, a facet of its chemistry that is

271 up transformations that deviate from epoxide ring-opening reactions, discovered through nanomechanica

272 ion, cohalogenation, oxidation, cyclization, ring-opening reactions, substitution, rearrangement, hyd

273 ,2- and 1,3-diamine derivatives by selective ring-opening reactions.

274 lates, upon treatment with BF3.OEt2, undergo ring-opening rearrangement and the Nef reaction to give

275 A mechanism is proposed that involves a ring-opening/ring-closing (Dimroth) rearrangement.

276 ucture of the methylene aziridine promotes a ring-opening/ring-closing cascade that efficiently trans

277 cluding a highly stereoselective epoxidation/ring opening sequence and an oxidative rearrangement of

278 -closing metathesis/base-induced eliminative ring opening sequence was used.

279 Computational studies for the ring-opening step, as well as the nature of the o-quinom

280 y play an important role in the cyclopropane ring-opening step.

281 This ring opening strategy may open a new avenue for the deve

282 hydratases, this lyase might represent a new ring-opening strategy for the degradation of polycyclic

283 isoquinolines involves, besides the triazole ring opening, the unusual migration of the cyano group.

284 he dioxirane, the latter in competition with ring opening to carbonyl oxide followed by hydration.

285 a shallow minimum with a very low barrier to ring opening to cyclooctadienediyne.

286 ium intermediate and subsequent nucleophilic ring opening to forge the C-N bond.

287 ism, which describes all stages from initial ring opening to formation of (E)-1-hydroxy-2-methylbut-2

288 chromophores, undergo facile thermochemical ring opening to fused gamma-lactones.

289 matrix photolysis of 9T/9A at 254 nm causes ring opening to generate two conformers of (o-cyanopheny

290 hich readily undergoes photo-oxygenation and ring opening to yield a fullerene with a hole in the cag

291 f the aziridines, which undergo nucleophilic ring opening to yield enantioenriched amines with no ero

292 nclude IMDA cycloadditions and retro-Mannich ring-openings to form both the AB and the EF ring fragme

293 The primary products underwent a triazole ring opening under the basic arylation conditions, provi

294 FEPO functions via epoxide ring opening upon nucleophilic attack of H2S.

295 A sequence of epoxide ring opening using N-deprotonated 1,2-azaborines followe

296 type 1 for 1b (WST11) upon taurine-driven E-ring opening, we hypothesized that taurine-driven E-ring

297 ster groups at the carboxylic position favor ring opening, whereas amides allow competition between t

298 none products can be isolated or can undergo ring-opening with benzylamine followed by aminolysis of

299 ontrolled DMDO oxidation; subsequent epoxide ring-openings with various nucleophiles can proceed with

300 either spontaneous depurination or imidazole-ring opening yielding formamidopyrimidine AFB1 (AFB1-Fap