ライフサイエンスコーパス: roadmap

1 emissions reduction by 2050 (European Energy Roadmap).

2 ry in the next-generation nonvolatile memory roadmap.

3 ation paths in a compact graph structure, or roadmap.

4 protein and choosing the best path from the roadmap.

5 tions to implement this important scientific roadmap.

6 ould inform current updates of protocols and roadmaps.

7 By following the proposed roadmap, a bridge can be built between basic and applied

8 cs, towards establishing an opto-electronics roadmap, akin to the International Technology Roadmap fo

9 tudy design selection framework to provide a roadmap and description of methods that may be utilized

10 thy blood epigenomes from the BLUEPRINT, NIH ROADMAP and ENCODE consortia by their cell type.

11 igenomic resources by ENCODE, the Epigenomic Roadmap and others has led to strategies that seek to in

12 e potential to generate a therapeutic target roadmap and rejuvenate the current drug-discovery pathwa

13 ) features are correlated with blocks on the roadmap (and therefore histological slides).

14 terrogation of Encyclopedia of DNA Elements, Roadmap, and other data sets.

15 Hence, comprehensive developmental roadmaps are crucial to channel stem-cell differentiatio

16 tprocess the replica exchange data using our roadmap-based MaxFlux reaction path algorithm to reveal

17 Our roadmap-based reaction path algorithm is a general tool

18 ced exposure rates in units so equipped, but roadmapping caused a silent switch to continuous fluoros

19 specific epigenomics annotations from ENCODE/Roadmap consortium covering 127 cell/tissue types and 8

20 tics analysis of eQTL and histone marks from Roadmap data has evidenced a possible role of the identi

21 erence to this native cardiogenic expression roadmap, divergent induced pluripotent stem cell-derived

22 latory regions in various cells using Encode Roadmap DNase-hypersensitive site data.

23 In particular, the Roadmap does not address the need for studies of unique

24 We then present a roadmap emerging as one possible future for quantitative

25 Collectively, this roadmap enables navigation of mesodermal development to

26 The development of the TCGA Roadmap engine was found to provide specific clues about

27 and the National Institutes of Health (NIH) Roadmap Epigenetics Program have now annotated more than

28 ing ChromDiff to the 127 epigenomes from the Roadmap Epigenomics and ENCODE projects, we provide nove

29 epressive) for 98 additional cell types from Roadmap Epigenomics and ENCODE projects.

30 g amount of regulatory data from the ENCODE, Roadmap Epigenomics and other consortia provides a wealt

31 om IDEAS is uniformly more accurate than the Roadmap Epigenomics annotation and the improvement is su

32 ase I hypersensitive regions from ENCODE and Roadmap Epigenomics cell lines.

33 To address this need, the NIH Roadmap Epigenomics Consortium generated the largest col

34 The Roadmap Epigenomics Consortium has published whole-genom

35 an Reference Epigenome Map, generated by the Roadmap Epigenomics Consortium, contains thousands of ge

36 existing methods, including that used by the Roadmap Epigenomics Consortium.

37 Integrating meQTL and Roadmap Epigenomics data could assist fine-mapping effor

38 ata sets (CpG Shore data, THREE data and NIH Roadmap Epigenomics data), studied previously in other w

39 an interact with EpiCompare by investigating Roadmap Epigenomics data, or uploading their own data fo

40 NIH projects such as ENCODE and Roadmap Epigenomics have revealed surprising complexity

41 The NIH Roadmap Epigenomics Mapping Consortium aims to produce a

42 rimental datasets, we compared the IDEAS and Roadmap Epigenomics maps.

43 aedia of DNA Elements consortium and the NIH Roadmap Epigenomics Project to predict haploinsufficienc

44 g information from the ENCODE Consortium and Roadmap Epigenomics Project to prioritize variants for p

45 and histone modification from ENCODE and the Roadmap Epigenomics Project, as well as through in vivo

46 seq datasets from different tissues from the Roadmap Epigenomics Project, ME-Class significantly outp

47 Large-scale epigenome mapping by the NIH Roadmap Epigenomics Project, the ENCODE Consortium and t

48 lysing 111 reference epigenomes from the NIH Roadmap Epigenomics project, we determine tissue-specifi

49 27 reference epigenomes from ENCODE 2012 and Roadmap Epigenomics, incorporating regulator binding dat

50 Overall, these observations provide a roadmap for a 'human knockout project', a systematic eff

51 then push thematic boundaries to elaborate a roadmap for a broader, solution-oriented, and transdisci

52 create a clinical, educational, and research roadmap for academic departments of neurology to thrive

53 esent synthetic strategy provides a rational roadmap for accessing more accurate models of the biolog

54 The key areas identified provide a roadmap for action regarding the continued use of polymy

55 nges to studying this population and offer a roadmap for an ethical approach to conducting research o

56 Richerson et al. provide a much needed roadmap for assessing cultural group selection (CGS) the

57 ng the volatile metabolites can be used as a roadmap for biotechnological applications, namely to imp

58 in the virion, which could further provide a roadmap for capsid assembly.

59 These findings may provide a roadmap for connecting the molecular-level kinetics of g

60 ed with the genome sequence data, provides a roadmap for constructing enhanced T. reesei strains for

61 in which activation occurs, could provide a roadmap for creating neuroprosthetics that feel as if th

62 We suggest a roadmap for decomposition ecology and forensic entomolog

63 ential housekeeping mechanism and provides a roadmap for defining the function of HSF1 as a driver of

64 We provide a roadmap for designing, evaluating, and modeling interven

65 This article will provide a roadmap for developing a quality assurance program for e

66 In this paper we propose a roadmap for developing an open source cardiovascular cir

67 These guidelines provide a roadmap for developing integrated, evidence-based, and p

68 se into a larger picture providing a general roadmap for development of autonomic neurons.

69 monstrated a bioinformatics-driven discovery roadmap for drug repurposing and development in overcomi

70 f definitive endoderm to generate a coherent roadmap for endoderm differentiation.

71 ng pattern of glyphosate provides a valuable roadmap for engineering new herbicides and herbicide-res

72 To provide a roadmap for exploration of the multiple roles of UL21, w

73 e human pancreatic islet cistrome provides a roadmap for exploring the effects of these variants and

74 These results offer a roadmap for further functional characterizations of the

75 energy conversion and storage, outlining the roadmap for future applications.

76 Here, we provide a roadmap for future experiments to explore the nature of

77 an evolutionary framework, but to provide a roadmap for future genetic studies.

78 This parcellation should serve as a roadmap for future investigations aimed at understanding

79 to gas-phase transfer of IDPs and provide a roadmap for future investigations into flexible systems

80 electronic applications, thereby providing a roadmap for future research and development.

81 tal and evolutionary lineages, and present a roadmap for future research.

82 roaches might be challenged to develop a new roadmap for future research.

83 t of structural brain measures) and define a roadmap for future studies investigating the genetic cov

84 architectures described here can serve as a roadmap for future studies of effector function and evol

85 pathological anxiety and thereby provides a roadmap for future therapeutic development.

86 for the clinical activity of CAL-101, and a roadmap for future therapeutic development.

87 We conclude with a roadmap for future work in this area, outlining axes alo

88 ing sepsis diagnostic criteria and provide a roadmap for future work.

89 ogress in establishing the complete cellular roadmap for haematopoietic lineage commitment will permi

90 In this respect, CERN is a roadmap for how a region can prepare to respond to publi

91 many respects, the supplement can serve as a roadmap for how to move from general consensus around to

92 ation provided in this essay will serve as a roadmap for hypothesis-driven, experimentally validated

93 Our study provides a roadmap for identification and analysis of lincRNAs in m

94 cells, and delineate a generally applicable roadmap for identifying functional Notch sites in cellul

95 quantitative and categorical data provides a roadmap for interrogating the wide-ranging toxicity data

96 e for loss-of-function screens, as well as a roadmap for its application to biological discovery.

97 n and development of the Wasp System and the roadmap for its community development.

98 for regulation of ADAM activity and offer a roadmap for its modulation.

99 ed in trafficking the beta1-AR and provide a roadmap for its trafficking via type I PDZs versus non-P

100 In the present article, we present a roadmap for metabolomic analyses in epidemiologic studie

101 is the 2012 World Health Organization (WHO) Roadmap for Neglected Tropical Diseases (NTDs) where the

102 We provide a roadmap for new science needed to improve the representa

103 to approach these questions and to develop a roadmap for personalized prognosis and treatment managem

104 sm to bone and unveil a readily translatable roadmap for programming cellular trafficking by chemical

105 hallenges and delineates the principles on a roadmap for rational application of precision medicine t

106 skeletal muscle diseases, but also provide a roadmap for recapitulating skeletal myogenesis in vitro

107 These advances illustrate a potential roadmap for regenerative medicine using molecular tools

108 We present a roadmap for research to address whether wildflower garde

109 The International Technology Roadmap for Semiconductors challenges the device researc

110 The International Technology Roadmap for Semiconductors has identified the electron's

111 The authors of the International Technology Roadmap for Semiconductors-the industry consensus set of

112 nm discussed in the International Technology Roadmap for Semiconductors.

113 oadmap, akin to the International Technology Roadmap for Semiconductors.

114 Our study provides a roadmap for setting national health priorities.

115 hlight current challenges but also provide a roadmap for software selection to answer specific resear

116 ropose that this general strategy provides a roadmap for successful identification of critical molecu

117 ws is that a wide range of options suggest a roadmap for sustainable water management and use in the

118 rn established in this study thus provides a roadmap for the analyses of physiological functions of c

119 This report offers a strategic roadmap for the CT user and research and manufacturer co

120 survivors have not answered and to develop a roadmap for the design and implementation of studies wit

121 monizing Outcomes Measures for Eczema (HOME) roadmap for the development and implementation of COSs,

122 d selective GBA2 inhibitors, also provides a roadmap for the development of high-throughput assays fo

123 g antibodies to HIV-1, providing a potential roadmap for the development of HIV-1 vaccine strategies

124 The study proposes a possible roadmap for the ethical assessment of sham surgery clini

125 Our work provides a roadmap for the experimental realizations of highly effi

126 Our study provides a roadmap for the immunogenicity of SARS-CoV and types of

127 digital SERS protocol, suggested here, is a roadmap for the implementation of SM-SERS as a routine t

128 Correction for 'An updated roadmap for the integration of metal-organic frameworks

129 cuss how technical advances facilitate a new roadmap for the isolation and analysis of macrophages at

130 Collectively, these three articles provide a roadmap for the most important emerging trends in GPCR p

131 with a ligand and provides a pharmacological roadmap for the rational design of small molecules as po

132 We provide an RNA-seq roadmap for the stress-sensitive vDG.

133 The network will provide a roadmap for the structural and functional elucidation of

134 of influenza-induced lethality and provide a roadmap for the systematic dissection of infection-assoc

135 implications of these findings and suggest a roadmap for the use of genetics in the detection of earl

136 results offer both a quantitative synthesis roadmap for this important class of functional oxides, a

137 was used to construct a continuous molecular roadmap for three independent reprogramming systems.

138 um will provide intensivists with a detailed roadmap for training.

139 ied aspects of gas sensing and with the 2025 roadmap for ubiquitous gas monitoring.

140 Our study provides a roadmap for understanding the genetic basis of miRNA exp

141 opportunity to present a neurodevelopmental roadmap for understanding, preventing, and treating psyc

142 rrent concepts in BAV genetics and propose a roadmap for unraveling unanswered questions about BAV th

143 vide a combined experimental and theoretical roadmap for using time-resolved extreme UV spectroscopy

144 eting delegates agreed on taking a step-wise roadmap for which the first output would be a consensus

145 lable to provide the necessary developmental roadmaps for in vitro differentiation.

146 We also provide a 'roadmap' for selection of appropriate labeling technique

147 s guided by magnetic resonance imaging (MRI) roadmaps fused with live X-ray.

148 and pin-point the conceptual interest of the roadmap given therein.

149 progress in scaling up and also in achieving Roadmap goals.

150 provide a detailed picture of the regulatory roadmap governed by XBP1 in distinct cell types as well

151 l Institutes of Health--for example, the NIH Roadmap--has focused on aspects of systems biology and t

152 ge data sets that serve as a gene expression roadmap highlighting gene expression changes during huma

153 The Roadmap identifies the most compelling opportunities in

154 Based upon those studies, we discuss a roadmap in which even more assays may be combined in a w

155 k, part of the National Institutes of Health Roadmap Initiative, aims to improve appreciably how PROs

156 or Biomedical Computing funded under the NIH Roadmap Initiative.

157 N), which is a National Institutes of Health Roadmap Initiative.

158 04 as a component of the Molecular Libraries Roadmap Initiatives of the US National Institutes of Hea

159 This sketch also serves as a roadmap into the vast and exciting new landscape of ques

160 The NIH Roadmap is a set of bold initiatives aimed at accelerati

161 We believe that the HOME roadmap is a useful methodological framework to develop

162 The proposed roadmap is based on the following 4 steps/levels: safety

163 Such a roadmap is particularly relevant for early-childhood-ons

164 evelopment of 2D colloids, and plots a clear roadmap - "lamellar solid - LCs - macroscopic fibers - f

165 s with other cellular events in the emerging roadmap leading to neurodegeneration.

166 graph-theoretic approach, the probabilistic roadmap method (PRM).

167 he current knowledge base and the scientific roadmap needed to advance the field.

168 ificity that together delineate a phenotypic roadmap of disease progression culminating in serially t

169 Therefore, we generated a roadmap of hepatic PXR bindings in the entire mouse geno

170 ican Heart Failure clinical trials provide a roadmap of how this promise may soon be realized.

171 es in current knowledge are used to create a roadmap of key questions to be answered in future resear

172 2016, the Blue Ribbon Panel (BRP) set out a roadmap of recommendations designed to exploit new advan

173 These profiles provide a roadmap of stress-induced changes in a genetically homog

174 an important functional relationship to the roadmap of T-cell development.

175 We conclude with a roadmap of the conceptual, methodological, practical, an

176 aid navigation across this site, a clickable roadmap of the main features provides easy access to the

177 s study provides an immunogenic and anatomic roadmap of the most likely non-HLA antigens that can gen

178 m thousands of sequences providing a genetic roadmap of their development.

179 Here we provide a roadmap of these advances and identify hitherto unrecogn

180 In this white paper, we outline a roadmap of what needs to be done to make this translatio

181 ene expression to trace the transcriptional "roadmap" of individual CD4+ T cells throughout immunothe

182 ng' approaches to trace the transcriptional 'roadmap' of individual CD8(+) T lymphocytes throughout t

183 Overall, our work provides a roadmap on how Boolean network modeling can be used as a

184 More recently, we have applied roadmap planning to the problem of protein folding.

185 and current challenges are highlighted as a roadmap proposal for research in this emerging field.

186 The recently published NIH Roadmap proposes that public-sector science should place

187 The chromophore design roadmap provided herein gives rise to octopolar supermol

188 isualization of these data and will act as a roadmap relating molecules to cells, circuits, and compu

189 METHODS AND ROADMAP (Risk Assessment and Comparative Effectiveness o

190 is paper, we establish the use of Stochastic Roadmap Simulation (SRS) for the study of ligand-protein

191 conformations and transitions as stochastic roadmap simulation or SRS.

192 S allows us to analyze all the paths in this roadmap simultaneously.

193 The prospective observational ROADMAP study (Risk Assessment and Comparative Effective

194 This research roadmap summarizes key gaps in our current understanding

195 This study provides a translational roadmap that is important for understanding human psycho

196 rame this work as a unique six-step approach roadmap that may serve as an efficient and cost effectiv

197 nd we provide a comprehensive transcriptomic roadmap that sheds new light on the molecular mechanisms

198 protein interactions, providing provisional roadmaps that can be explored using experimental approac

199 Thus, GWAS are useful "roadmaps" that require functional analysis to establish

200 relationship of metal nanowire networks as a roadmap, this Progress Report describes different synthe

201 dly, these findings illuminate an actionable roadmap to a more general and automated approach for sma

202 These results provide a therapeutic roadmap to achieve hepatic regeneration without provokin

203 ess and challenges, and identify a potential roadmap to address the gap.

204 ogether these approaches outline a potential roadmap to an era of quantum phenomena on demand.

205 e (DHS) information from the NIH Epigenomics Roadmap to construct an improved reference DNA methylati

206 Our results provide a roadmap to develop a single antibody-based treatment eff

207 rces that shaped each peptidase family and a roadmap to develop a timeline for their expansion as an

208 Our study provides a practical roadmap to develop effective human HCC vaccines that may

209 titis C virus infection provide an important roadmap to develop potent and broadly directed vaccine c

210 ) cancer progression model is presented as a roadmap to dissect the complexity inherent to this disea

211 nent MEDLINE published reports and develop a roadmap to elucidate the molecular steps of carcinogenes

212 nd analysis of wheat's progenitor provides a roadmap to enhance genomics-assisted breeding and improv

213 These studies provide a roadmap to exploit genomic analyses by directing investi

214 features of an ideal platform and provide a roadmap to facilitate the efficient writing of large gen

215 Our results will serve as a roadmap to formulate more effective target functions to

216 We have developed a strategic five-phase roadmap to foster the clinical validation of biomarkers

217 dies have identified several molecules and a roadmap to generate additional agents that could be exam

218 the cofactor binding site, which provided a roadmap to guide further optimization of this lead compo

219 for each particle we develop a foundational roadmap to guide future investigations.

220 every type of cancer will provide a powerful roadmap to guide therapeutic approaches.

221 s deduced from this work provide a potential roadmap to help steer drug discovery efforts for this an

222 The workshop aimed to provide a roadmap to help strategically guide research efforts dur

223 and mouse genomes and suggests an affordable roadmap to high-quality references for thousands of spec

224 markers for the development of a data-driven roadmap to inform risk stratification and therapeutic de

225 tions, pan-cancer network analyses provide a roadmap to investigate new diagnostic and therapeutic op

226 WHO has defined a Roadmap to reach 2020 targets, which was endorsed by mem

227 on of molecular structure reveals the hidden roadmap to significantly enrich the variety of building

228 search are proposed in an updated high-level roadmap to stimulate the next steps towards MOF-based mi

229 ndents felt they lacked understanding of the roadmap to success and formal assistance in career devel

230 ation of the extent of disease and provide a roadmap to surgery as well as detect recurrence and meta

231 The resulting roadmap to symmetry breaking paves the way for determini

232 ids in regulating TNFalpha levels provides a roadmap to tailored TB treatment based on host genotype.

233 egrative approaches presented here provide a roadmap to uncover the therapeutic potential of transcri

234 signatory countries that will require clear roadmaps to set priorities over the next 15 years.

235 Phase diagrams provide 'roadmaps' to the possible states of matter.

236 ested in developing HTA reports to provide a roadmap toward these objectives.

237 wborn Action Plan provides an evidence-based roadmap towards care for every woman, and a healthy star

238 These results reveal a roadmap towards future ultradense nanophotonic integrate

239 d not influence contrast volume or number of roadmaps used during the "real" case.

240 At the time, a roadmap was drawn that illustrates the location within t

241 Instead of just following the best path in a roadmap, we can calculate the contribution of all the po

242 se according to a stage-specific cardiogenic roadmap, we established a new paradigm of familial DCM p

243 To characterize this epigenomic roadmap, we have performed MethylC-seq, ChIP-seq (H3K4/K

244 ost recent manufacturing data and technology roadmaps, we compare present and projected environmental

245 The roadmaps would harness the power of business to reduce h