ライフサイエンスコーパス: rod

1 e of the fluctuations at any location of the rod.

2 diac/slow skeletal muscle myosin heavy chain rod.

3 required for selective chromatin closure in rods.

4 es that were cut perpendicular to the enamel rods.

5 ated rods negatively impact treated, rescued rods.

6 ng surviving cone photoreceptors compared to rods.

7 -dimensional (3D) magnetic structure of nano-rods.

8 and, they form fewer multi-PSD contacts with rods.

9 (p-benzoic acid)pyrene; H4TBAPy)-based MOFs: ROD-7 (In2(OH)2TBAPy, frz), NU-901 (scu), and NU-1000 (c

10 ts axial portions function as a drive shaft (rod), a universal joint (hook) and a helical propeller (

11 Birds have six types of photoreceptors: rods, active in dim light, double cones that are thought

12 Rods, active under dim illumination, are thought to satu

13 ion is not well defined; some studies report rod activity well into the photopic range.

14 The flagellar rod acts as a driveshaft to transmit torque from the cyt

15 We further find that in rods, alpha2delta4 is crucial for organizing synaptic ri

16 ide) is sandwiched between an upper rotating rod and bottom nonmoving generator and collector planar

17 Here we report the structure of the rod and comparison with that of the hook.

18 During recovery, rod and cone bipolar cells exhibit markedly different re

19 ents, and electrodiagnostic testing revealed rod and cone dysfunction in the 5 patients tested.

20 divide patients into cohorts by severity of rod and cone dysfunction.

21 ized by time- and dose-dependent declines in rod and cone photoreceptor functions as early as 120 day

22 Retinal rod and cone photoreceptors arguably represent the best-

23 The light responses of rod and cone photoreceptors have been studied electrophy

24 degeneration: early dysfunction and loss of rod and cone photoreceptors in the outer retina and, pro

25 Rod and cone photoreceptors support vision across large

26 Both groups had markedly reduced rod and cone responses, but nonsyndromic USH2A patients

27 For most patients, the degree of rod and cone sensitivity losses showed a relationship, t

28 phore to its all-trans configuration in both rod and cone vertebrate photoreceptors.

29 respectively, conferring the rigidity on the rod and flexibility on the hook.

30 The rod and hook are directly connected to each other, with

31 tight and loose axial subunit packing in the rod and hook, respectively, conferring the rigidity on t

32 d bright-light color vision are initiated in rod and several types of cone photoreceptors, respective

33 lei at 240 days of age ( approximately 36.8% rods and approximately 19.9% cones).

34 Both rods and cones adapt to background light and to bleaches

35 the adult mammalian retina can reconnect to rods and cones and restore retinal sensitivity at scotop

36 ey rods and cones respond to light much like rods and cones in amphibians and mammals.

37 The function of rods and cones in children born extremely preterm has no

38 rtebrates with properties much like those of rods and cones in existing vertebrate species.

39 We have previously shown that rods and cones in lamprey respond to light much like pho

40 toreceptor cells, such as ciliary vertebrate rods and cones or protostome microvillar eye photorecept

41 We show that lamprey rods and cones respond to light much like rods and cones

42 butes to visual-pigment renewal in mammalian rods and cones through a non-enzymatic process involving

43 and detailed; they argue for the presence of rods and cones very early in the evolution of vertebrate

44 nts of transcription factor binding sites in rods and cones, revealing key differences in the cis-reg

45 2A (PP2A) acts as opsin phosphatase in both rods and cones.

46 ame in lamprey and in amphibian or mammalian rods and cones; moreover background light shifts respons

47 vable asaccharolytic anaerobic Gram-positive rods and other uncultivable Gram-negative rods, and, rar

48 or alignment was assessed with double Maddox rods and prism and alternate cover tests preoperatively,

49 f dimerization, downsizing of phycobilisomes rods and regulation of zeaxanthin abundance.

50 ion in dim light depends on synapses between rods and rod bipolar cells (RBCs).

51 opportunistic microorganisms such as enteric rods and Staphylococcus aureus.

52 ic landscape, we performed ATAC-seq on mouse rods and their most closely related cell type, cone phot

53 In zebrafish, although quite different from rods and UV cones, RGB cones (red, green, and blue cones

54 ells (thick-walled spheres, filament-forming rods) and intra-microfossil Fe minerals are consistent w

55 of two ping-pong balls connected by a rigid rod, and its two balls are filled with granular particle

56 TS revealed predominant change in trabecular rods, and EDX confirmed less mineralization.

57 ve rods and other uncultivable Gram-negative rods, and, rarely, opportunistic microorganisms such as

58 In particular, larger rod- and disk-shaped PEG NPs show more uptake than small

59 igurations, in which single release sites of rods are apposed by one to three postsynaptic densities

60 The well-aligned metal rods are confined and separated by the wood vessels, whi

61 cially when cardiac problems or intranuclear rods are present.

62 these conditions it is widely believed that rods are saturated and do not contribute substantially t

63 geted chemical biology approach, we identify ROD as the Spindly farnesyl receptor.

64 gy should determine if there is an effect on rod as well as cone function and structure.

65 nce of photoreceptor identity, and highlight rods as an attractive system for studying the relationsh

66 s that are a mosaic of treated and untreated rods, as well as cones.

67 the state diagram and find that short active rods at sufficiently high density exhibit a glass transi

68 ects are caused by the release of talin head-rod autoinhibition.

69 Rod basal outer disks displayed excessive outgrowth, and

70 assembly of one-dimensional nanostructures (rods), based upon the systematic activation (DNA functio

71 recruitment in vivo and Spindly binding to a Rod beta-propeller-Zwilch complex in vitro.

72 ells, which stimulate the GABAC receptors at rod bipolar cell axons.

73 m light depends on synapses between rods and rod bipolar cells (RBCs).

74 nel of vision, which consists of sensitizing rod bipolar cells by a sustained GABAergic input origina

75 nswer this question we visualized individual rod bipolar cells in mouse retina during postnatal devel

76 e light sensitivity and operational range of rod bipolar cells, the retinal neurons operating immedia

77 from multiple rods is pooled into individual rod bipolar cells.

78 dendritic tips and transduction proteins in rod bipolar cells.

79 ate the possibility to probe 10-fold stiffer rods by a combination of superresolutive optical methods

80 ppression and quantified the kinetics of (i) rod cell clearance, (ii) MG/progenitor cell proliferatio

81 Peripheral macrophage cells responded to rod cell loss, as evidenced by morphological transitions

82 Neutrophils displayed no reactivity to rod cell loss.

83 To test function during rod cell regeneration, we coablated microglia and rod ce

84 MG/progenitor cell proliferation, and (iii) rod cell replacement.

85 10(5) free opsin molecules in a dark-adapted rod cell-a number that is three orders of magnitude high

86 ith round cells at the top of the colony and rod cells dominating the basal surface and edges.

87 The degeneration of rod cells is early onset, followed by the death of cone

88 ell regeneration, we coablated microglia and rod cells or applied immune suppression and quantified t

89 in rhodopsin, the light-sensitive protein of rod cells, are the most common cause of dominant retinit

90 As shown previously for rod cells, attenuation of constitutively active opsin ca

91 nsgenic mice expressing RDH10 ectopically in rod cells.

92 e an interaction with HSP90 and modulate the rod cGMP PDE6 stability and activity.

93 The Cngb1 locus-encoded beta-subunit of rod cGMP-gated cation channel and associated glutamic ac

94 to engineering nanostructures assembled from rod-coil block copolymers.

95 uctures could be controlled by adjusting the rod-coil block ratios.

96 e interaction begins when the centers of two rods collide at a random angle.

97 Melanopsin and rod+cone responses differed in the temporal domain, and

98 ash stimuli under conditions that target the rod, cone, and intrinsically-photosensitive (melanopsin)

99 Six patients with rod-cone degeneration and disease-causing mutations in M

100 redominance in 30% of patients, and showed a rod-cone dysfunction pattern in 20% of RP patients.

101 hysiologic testing in 6 patients confirmed a rod-cone dystrophy phenotype.

102 that CERKL deficiency in zebrafish may cause rod-cone dystrophy, but not cone-rod dystrophy, while in

103 10 patients, 4 had a progressive late-onset rod-cone dystrophy, with a mean (range) age at onset of

104 .7 (20-40) years, and 6 had an earlier onset rod-cone dystrophy, with a mean (range) age at onset of

105 of this study was to determine the extent of rod-, cone-, and melanopsin-mediated pupillary light ref

106 At the input level, the activation of rod/cone and suprachiasmatic nuclei (SCN) by light was p

107 etermined by the termination kinetics of the rod/cone circuits.

108 nol dehydrogenase 10 (RDH10), upregulated in rod/cone hybrid retinas and expressed abundantly in Mull

109 intensities, where only synaptically driven rod/cone input activates ipRGCs, the duration of the ipR

110 phototransduction pathway and as a relay for rod/cone input via synaptically driven responses.

111 mer light intensities that activate only the rod/cone pathway.

112 es in which visibility for melanopsin versus rods+cones was independently modulated, and we recorded

113 Here we study the behavior of self-propelled rods confined to a compact spherical manifold by means o

114 Each rod contained recombinant HIV-1 CN54gp140 protein (167mu

115 e first model dsDNA molecules as short rigid rods containing periodically spaced binding sites.

116 ting domain and ABD1, whereas the C-terminal rod contains the actin-anchoring ABD2 and ABD3.

117 marily by cones, but with melanopsin (and/or rods) contributing under more gradual changes.

118 However, rod dark adaptation was unaffected by the expression of

119 by immunofluorescence and western-blot that rod degeneration in CERKL-/- zebrafish occurred earlier

120 educed significantly at the fovea and in the rod-dense superior retina.

121 sis revealed lower cone densities and higher rod densities in the nocturnal than in the cathemeral an

122 fic roles of histone deacetylases (HDACs) in rod differentiation in neonatal mouse retinas, we used a

123 vides evidence into how the controlled talin rod domain unfolding acts as a key regulator of adhesion

124 omplexes to an RP phenotype characterized by rod-dominant functional defects and reductions in total

125 defect, Prph2Y/+/Rom1-/- animals displayed a rod-dominant phenotype and OSs similar to those seen in

126 ropia 10.7, P = .033; SE -3.10 D [SD 4.49]); rod dominated dystrophies (OR high myopia 10.1, P < .000

127 Similar rod-driven responses were observed in both ventral and d

128 f the POS and ellipsoid zone associated with rod dysfunction.

129 tosa (RP), two with autosomal recessive cone-rod dystrophy (CORD), and two with the related complex d

130 A form of canine cone-rod dystrophy (cord1) was originally associated with a h

131 al recessive retinitis pigmentosa (RP), cone-rod dystrophy (CRD) or cone dystrophy (CD) harboring pot

132 P1 cause Leber congenital amaurosis and cone-rod dystrophy in humans.

133 h may cause rod-cone dystrophy, but not cone-rod dystrophy, while interfering with the phagocytosis f

134 juvenile retinitis pigmentosa (RP) and cone-rod dystrophy.

135 ion, P(EDOT-PdBPI-co-HKCN) modified graphite rod electrode was improved for amperometric glucose sens

136 ces; while Prph2Y/+ animals exhibited a cone-rod electroretinogram defect, Prph2Y/+/Rom1-/- animals d

137 In rare cases, the two rods enter a second stage by rotating into parallel alig

138 Here we found that rods excite dark-adapted DACs across a wide range of sti

139 al retina-specific leucine zipper protein, a rod fate determinant during photoreceptor development.

140 In the rod [Formula: see text], Gaussian [Formula: see text] an

141 the present study, we focused on the central rod-free region of primate retina, the fovea, to specifi

142 Both rod function and cone function were reduced in children

143 rus vectors robustly sustained the rescue of rod function and preserved retinal structure in the dog

144 ogether, our results reveal an early loss of rod function in CNGB1-deficient patients and a wide wind

145 ehavioural experiments on subjects with only rod function reveals that these individuals unexpectedly

146 ocurrent in transgenic mice, which have only rod function, revealed the well-studied reduction in the

147 wild-type mice, but not in mice lacking the rod G-protein alpha subunit, transducin (Galphat), revea

148 Following Nrl disruption, rods gain partial features of cones and present with imp

149 Regulation of rod gene expression has emerged as a potential therapeut

150 r support that pharmacological modulation of rod gene expression provides a potential strategy for th

151 d with antidots, and with ferromagnetic nano-rods grown inside them.

152 ction, cardiac involvement, and intranuclear rods in biopsied muscle were observed in two individuals

153 -organization of outwardly radiating F-actin rods in cortical neurons from APPswe/PS1DeltaE9 mice.

154 ysates as well as formation of actin-cofilin rods in the brain sections of symptomatic mice with CM.

155 therefore, disrupt the function of cones and rods in these zebrafish and cause photoreceptor death.

156 The results suggest that rod inextensibility, not elastic response, dictates the

157 Thus, sensitization of the photovoltage by rod inner segment conductances appears to extend the ope

158 icroscopy showed increased autophagosomes in rod inner segments with HDAC inhibitor (HDACi) treatment

159 nail fixation (nail group; n = 161), a metal rod inserted into the hollow center of the tibia, vs loc

160 ing using a focal dark adaptometer measuring rod intercept time (RIT).

161 but show distinct mechanical properties; the rod is straight and rigid as a drive shaft whereas the h

162 synapse of this pathway, input from multiple rods is pooled into individual rod bipolar cells.

163 Here, we provide evidence that rod length is limited by the width of the periplasmic sp

164 herical AuNPs showed better enhancement than rod-like AuNPs during measurement.

165 ear rod myopathy is a subtype of NM in which rod-like bodies are seen in the nucleus, and it often ma

166 Herein, we show that rod-like cellulose nanocrystal (CNC)-based NP-surfactant

167 sotropic and nematic (I + N) coexistence for rod-like colloids is a signature of the first-order ther

168 The intrinsic stiffness and rod-like geometry of nanoscale components limit the cohe

169 Colloidal particles disturb the alignment of rod-like molecules of liquid crystals, giving rise to lo

170 ines the well-defined diameter and resulting rod-like morphology.

171 n order of magnitude less solid content than rod-like nanocomponents.

172 Furthermore, multishell rod-like nanostructures have been prepared with opticall

173 l cell types in mammals contain cilia, small rod-like or more elaborate structures that extend from t

174 ve structural features, and 3) enrichment in rod-like shapes over others.

175 nversion was measured for both isotropic and rod-like shells around beta-NaYF4 nanocrystals doped wit

176 s slow shell growth technique, we have grown rod-like shells around different almost spherical core n

177 fluorination of F-P3EHT leads to an extended rod-like single-chain conformation and hence highly orde

178 polymer can be tuned such that it forms a 1D rod-like structure in good solvent and a 2D lamellar str

179 inside silicon using 1 microm-sized dots and rod-like structures of adjustable length as basic buildi

180 nsity and morphology, including high-density rod-like structures, large spherical granules, and small

181 es in the heptad repeat of the mutant myosin rods likely alters interactions that stabilize coiled-co

182 iated by rods under dim lighting conditions, rods/M-cones/melanopsin under intermediate lighting cond

183 omatin profile of photoreceptors lacking the rod master regulator Nrl is nearly indistinguishable fro

184 that CRISPR/Cas9-mediated NRL disruption in rods may be a promising treatment option for patients wi

185 ; (3) no significant differences in the mean rod-mediated responses.

186 etry and multifocal ERG but with near-normal rod-mediated vision according to results of 2-color dark

187 V. cholerae has a characteristic curved rod morphology, with a longer outer face and a shorter i

188 Intranuclear rod myopathy is a subtype of NM in which rod-like bodies

189 isoform is capable of sensing the T3SS inner rod, needle, and flagellin.

190 ouse models to test whether dying, untreated rods negatively impact treated, rescued rods.

191 The rods of nocturnal mammals are unique among vertebrate ce

192 imited such studies to sufficiently flexible rods, of which the persistence length ([Formula: see tex

193 photoreceptors form selective contacts with rod ON-bipolar cells by aligning the presynaptic voltage

194 oning; phenotypes were assessed by assays of rod opsin in retinal extracts, and confocal microscopy o

195 in the central fovea and found evidence that rod opsin positive cells were absent and violet-sensitiv

196 The Exorh (rod opsin) gene has been retained in 56 genomes.

197 mation in cultured cells overexpressing P23H rod opsin, and increased rhodopsin aggregation in the P2

198 thologically attenuated without a documented rod or cone predominance in 30% of patients, and showed

199 ing bacterial morphology has been limited to rod- or coccal-shaped model systems.

200 d nanoparticles was observed that are mostly rod- or irregular-shaped depending on the structure of t

201 als that were weakly attached, regardless of rod orientation.

202 photoactivated one rhodopsin per Galphat the rod OS swelling response reached a saturated elongation

203 we find the H2O membrane permeability of the rod OS to be (2.6 +/- 0.4) x 10(-5) cms(-1), comparable

204 O permeability of nascent discs in the basal rod OS.

205 a 200-fold intensity range caused correlated rod outer segment (OS) elongation and increased light sc

206 PRPH2 oligomerizes with its homologue rod outer segment (OS) membrane protein 1 (ROM1), and no

207 noids, all-trans-retinal, is released in the rod outer segment by photoactivated rhodopsin after ligh

208 Our data indicate RPGRIP1 is necessary for rod outer segment development through regulating ciliary

209 Measurements of the rod outer segment photocurrent in transgenic mice, which

210 as substantial as the desensitization of the rod outer segment photocurrent.

211 r levels of all-trans-retinal and retinol in rod outer segments following light exposure.

212 is a G protein-coupled receptor found in the rod outer segments in the retina, which triggers a visua

213 d to increased structural instability of the rod outer segments.

214 tion if the columns aggregate in a hexagonal rod packing.

215 ies, primarily through connexin-36-dependent rod pathways.

216 talytic activity of heterologously expressed rod PDE6.

217 , and retinal microglia responses to induced rod photoreceptor apoptosis.

218 Rod photoreceptor dysfunction is observed in Reep6-/- mi

219 ound, Photoregulin3 (PR3) that also inhibits rod photoreceptor gene expression, potentially though Nr

220 for efficient enrichment of rhodopsin within rod photoreceptor sensory cilia, inhibited enrichment of

221 ously reported the identification of a novel rod photoreceptor specific isoform of Receptor Expressio

222 In the mammalian retina, rod photoreceptors form selective contacts with rod ON-b

223 BP removes all-trans-retinol from individual rod photoreceptors in a concentration-dependent manner.

224 Here, we show that rod photoreceptors in mice rely on glycolysis for their

225 ssessed the arrangements of retinal cone and rod photoreceptors in six nocturnal, three cathemeral an

226 rative disease, in which the death of mutant rod photoreceptors leads secondarily to the non-cell aut

227 st notably a block in the differentiation of rod photoreceptors.

228 otent stem cells (iPSCs) derived from murine rod photoreceptors.

229 ursors in real time in single isolated mouse rod photoreceptors.

230 neurons operating immediately downstream of rod photoreceptors.

231 sicles to selected membrane sites in retinal rod photoreceptors.

232 repancy by characterizing the sensitivity of rod photoresponses following exposure to bright bleachin

233 well-studied reduction in the sensitivity of rod photoresponses following pigment bleaching.

234 ces appears to extend the operating range of rod phototransduction following pigment bleaching.

235 ical inner segment and reduction in selected rod phototransduction proteins.

236 A model of rod phototransduction suggests that phototransduction ga

237 e visual pigment, the desensitization of the rod photovoltage is not as substantial as the desensitiz

238 sual pigment produced an acceleration of the rod photovoltage with respect to the outer segment photo

239 senses the Salmonella Typhimurium T3SS inner rod protein PrgJ and that T3SS inner rod proteins from m

240 dle protein, NAIP2 recognizes the T3SS inner rod protein, and NAIP5 and NAIP6 recognize flagellin.

241 S inner rod protein PrgJ and that T3SS inner rod proteins from multiple bacterial species are also de

242 simulations of neurons as discrete, elastic rods provide evidence that a balance of torque, tension,

243 e that stepwise destabilization of the talin rod R3 subdomain decreases cellular traction force gener

244 Rod-RBC synapses develop while 7% of RBCs undergo progr

245 Surprisingly, rods recover faster at higher light levels.

246 djustments and bleaching adaptation underlie rod recovery.

247 thousands of loci are selectively closed in rods relative to cones as well as >60 additional cell ty

248 Consistently, exogenous chromophore reduces rod responses at bright background.

249 e photopic range increases the robustness of rod responses.

250 We show that Rod's N-terminal beta-propeller and the associated Zwilc

251 The extent of rod saturation is not well defined; some studies report

252 The rod self-assembles to a defined length of 25 nanometers

253 c rates-properties of rhodopsin that mediate rod sensitivity and visual performance.

254 FST permitted quantitation of cone and rod sensitivity in these patients with severe visual imp

255 which lysis occurs while the cells retain a rod shape, revertant alleles with second-site suppressor

256 a, as many biofilm-forming bacteria that are rod-shaped and motile on soft surfaces exhibit polymertr

257 on and at the side-wall during elongation in rod-shaped and ovococcoid Gram-positive bacteria.

258 gA mutant lost the characteristic Salmonella rod-shaped appearance, exhibited increased sensitivity t

259 crystal structure reveals an unusual locked rod-shaped array.

260 ingle Ag or Cu atom into a centrally hollow, rod-shaped Au24 nanoparticle, forming AgAu24 and CuAu24

261 into a new model of cell wall biogenesis in rod-shaped bacteria.

262 ties of postnatal myocardium, including: (1) rod-shaped cardiomyocytes with M bands assembled as a fu

263 In rod-shaped cartilage structures (Meckel, ribs and skelet

264 oriented in Epulopiscium than in most small rod-shaped cells.

265 spots, not stripes, which then elongate into rod-shaped digit rays by incorporating new cells at thei

266 Rod-shaped fission yeast cells grow in a highly polarize

267 , which consists of oriented hard-phase SmCo rod-shaped grains and soft-phase Fe(Co) equiaxed grains

268 n proteins bind guanine nucleotides and form rod-shaped hetero-oligomers.

269 Rod-shaped Myxococcus xanthus cells are polarized with p

270 -Phenylene tetramers have been combined with rod-shaped p-phenylene-, tolane-, and diphenylbutadiyene

271 The rod-shaped virus APBV1 (Aeropyrum pernix bacilliform vir

272 lastomer body into which three freeze-dried, rod-shaped, hydroxypropylmethylcellulose inserts were in

273 lular distribution and function of PS in the rod-shaped, polarized fission yeast.

274 ved survival in the presence of mutations in rod-specific genes, consequently preventing secondary co

275 Hes1 with concomitant block of expression of rod-specific genes.

276 r phototransduction, disk morphogenesis, and rod structural integrity.

277 el where in the hydrated state the organized rod structure of the phycobilisome supports directional

278 Force induced unfolding of talin rod subdomains has been proposed to act as a cellular me

279 orm derives from the elastic buckling of the rods subjected to inextensibility.

280 o rely on their vision from only S-cones and rods, suffer severely reduced visual acuity and impaired

281 e an unprecedented data set derived from 274 rod surface-elevation table-marker horizon stations, to

282 ration, the treatment substantially improves rod survival and preserves cone function.

283 olishing expression of CNG channels prolongs rod survival caused by elevated cGMP in a PDE6 mutant mo

284 2delta4, which complexes with CaV1.4 and the rod synaptogenic mediator, ELFN1, for trans-synaptic ali

285 Two gram-negative anaerobic rod taxa, Prevotella and Porphyromonas, predominated, co

286 nally, in the larval retina, we investigated rod telodendria and UV cone telodendria in mutant and tr

287 We also found that larval rod telodendria are less abundant than short wavelength

288 gen (H2) from water heater sacrificial anode rods than does presence of copper dosed as soluble cupri

289 prise an initially planar network of elastic rods that are actuated into a shell-like structure by lo

290 s, are millimeter-long, axisymmetric, silica rods that are tapered along their lengths.

291 t and found such responses to be mediated by rods under dim lighting conditions, rods/M-cones/melanop

292 of these thermal For each individual studied rod, we performed a second measure of its rigidity by de

293 In the second model, treated and untreated rods were diffusely intermixed, and their ratio was cont

294 In one model, treated and untreated rods were segregated.

295 ed by the expression of RDH10 and transgenic rods were unable to use cis-retinol for pigment regenera

296 r or parallel to the direction of the enamel rods, were exposed to a PPi-stabilized supersaturated ca

297 the acoustic phonons in a single zinc oxide rod with a spatial resolution of 50 nm and a temporal re

298 mparison, membranes composed of a mixture of rods with opposite chiralities can have the edge twist o

299 f a nanorod, as well as the gaps between two rods, with different DNA strands allows one to synthesiz

300 describe the molecular mechanism used by the Rod-Zw10-Zwilch complex and the adaptor Spindly to recru

301 adaptor protein Spindly are recruited to the ROD-Zw10-Zwilch complex in the fibrous corona of unattac