ライフサイエンスコーパス: rodent

1 versal of the effects of NMDA antagonists in rodents.

2 lls and suppression of adult neurogenesis in rodents.

3 apitulates the meningeal lymphatic system of rodents.

4 use and human islets in vitro and in vivo in rodents.

5 causing the loss of up to 50% of neurons in rodents.

6 humans, but including migratory chains as in rodents.

7 nduce rapid antidepressant-like responses in rodents.

8 sociated with developmental neurotoxicity in rodents.

9 n relation to neurodevelopmental toxicity in rodents.

10 cholesterol metabolism in diet induced obese rodents.

11 obesity induced by a high-fat diet (HFD) in rodents.

12 ies in these oscillations between humans and rodents.

13 n timing impair spatial memory in humans and rodents.

14 synchronizing effects of light in nocturnal rodents.

15 lammation, and impair memory in normal adult rodents.

16 oratory behavior of mice and other nocturnal rodents.

17 dose studies, as well as in vivo testing in rodents.

18 ncreatitis is largely based on studies using rodents.

19 nked with cancer of the liver and stomach in rodents.

20 various electrodes and mechanical stimuli in rodents.

21 elopmental neurotoxicity (DNT) in humans and rodents.

22 n general, are not all identical to those in rodents.

23 preimplantation epiblast to gastrulation in rodents.

24 forms of plasticity in hippocampal slices of rodents.

25 t supplying the minimum I(-) requirement for rodents.

26 f neurogenic events in humans, compared with rodents.

27 s in the spindle range in naturally sleeping rodents.

28 neuronal death following ischemic stroke in rodents.

29 was shown to modulate cognitive functions in rodents.

30 tes, and in the beta cells of obese diabetic rodents.

31 tends lifespan in diverse species, including rodents.

32 edin B mRNA (Nmb), identifies RTN neurons in rodents.

33 se adiposity and circulating lipid levels in rodents.

34 culating growth hormone levels in humans and rodents.

35 As in rodent acini, human acini exposed to toxic concentration

36 ar to those previously observed in dispersed rodent acini.

37 ncreatitis-causing treatments as observed in rodent acini.

38 GP and NP were consistently found mutated in rodent-adapted Ebola virus strains.

39 hat exhibits high potency for both human and rodent alpha9alpha10 nAChRs, and was at least 1,000-fold

40 alignment between the responses of human and rodent alveolar bone to osteotomy site preparation.

41 cytochrome-oxidase activity in layer 4 of 8 rodent and 1 lagomorph species.

42 CNS, and we take into account differences in rodent and human CNS anatomy.

43 s of food sensitization, differences between rodent and human immune physiology limit the extension o

44 In primary cultured rodent and human macrophages, CB1R activation increased

45 re beta cells, recent analyses of transgenic rodent and human pancreata reveal a number of novel hete

46 ry impairment, complementing findings in the rodent and human postmortem literatures.

47 that ACSL6 plays in lipid synthesis in both rodent and human skeletal muscle.

48 During adolescence, both rodent and human studies have revealed dynamic changes i

49 inal fluid Abeta levels observed in both the rodent and the human.

50 y range of odors, we are more sensitive than rodents and dogs for some odors, we are capable of track

51 hysiological and neurobehavioral deficits in rodents and humans and therefore poses serious health ha

52 teria (LAB) have been observed in nematodes, rodents and humans for over a century, the mechanisms un

53 ogenesis, is expressed in islets of diabetic rodents and humans with T2D.

54 side present at high levels in the plasma of rodents and humans, is critical for RNA synthesis, glyco

55 mal injection of acid generates pain in both rodents and humans; however, few studies have addressed

56 vo electroporation strategy used in utero in rodents and in ovo in poultry, and apply it to posthatch

57 models proposed for head-direction cells in rodents and may shed light on how neural systems, in gen

58 explain why cannabinoid is not rewarding in rodents and might also account for individual difference

59 emically injected PAMs and NAMs of mGluRs in rodents and monkeys, focusing on whether they reduce dru

60 ation of operant drug self-administration in rodents and monkeys.

61 ng viral titre and ameliorating infection in rodents and neonatal lambs.

62 ystem responses to implanted biomaterials in rodents and non-human primates.

63 Yet compared with rodents and other experimental mammals, humans have a re

64 on cell and results of recent experiments in rodents and primates indicating that inputs to these neu

65 Here we highlight recent studies across rodents and primates showing how thalamus contributes to

66 presence of general intelligence in mammals (rodents and primates).

67 n the same clade, or evolutionary branch, as rodents and primates.

68 eous structures and spatial distributions in rodents and primates.

69 In turn, suppressed abundances of rodents and rabbits in the absence of dingoes relaxed a

70 ily crosses the blood-brain barrier (BBB) in rodents and selectively binds to TrkB/C receptors in viv

71 n, we used imiquimod-induced skin disease in rodents and showed that rats with genetic IL-22BP defici

72 plague, is a bacterium associated with wild rodents and their fleas.

73 y lead to unstable homeostatic conditions in rodents and therefore may alter kinetics.

74 tion, and region-specific delivery in small (rodent) and large (porcine and human) lungs.

75 e stress hormone cortisol (corticosterone in rodents) and is widely expressed in excitatory and inhib

76 ng maternal and paternal care, especially in rodents, and discuss the relationship between sex differ

77 xpression is highly dysregulated in stressed rodents, and identified a set of target genes involved i

78 sed detection of BPDE-N(2)-dG in BaP-treated rodents, and indirectly through high-performance liquid

79 at it also inhibits glial cell activation in rodents, and may alter opioid-mediated effects, includin

80 In rodents, and possibly in humans, exendin-4 can stimulate

81 is associated with infertility in humans and rodents, and treatments for human infertility show a dec

82 The Cyp3a1/2 KO rats are a novel rodent animal model that will be a powerful tool for the

83 studies, no equivalent tool is available for rodent animal samples.

84 the observation that anxiolytic drugs reduce rodent anxiety-like behavior.

85 Rodent approach-avoidance conflict tests are common prec

86 ular mechanisms involved in HSV infection in rodents are different from those in humans.

87 Experiments in rodents are necessary for studying the mechanisms of bra

88 Population trends for commensal rodents are the subject of interest and speculation but

89 Ca(2+) channel function and Ca(2+) fluxes in rodent as well as in human beta-cells.

90 x plasticity has been advanced greatly using rodents as experimental animals.

91 duced in cecal ligation and puncture-exposed rodents at 96 hours (75.34 +/- 13.2 vs 134.4 +/- 8.2 GPa

92 onnection is that between L5B neurons in the rodent barrel cortex (BC) and the posterior medial nucle

93 enhanced flexibility relative to neurons in rodents because they are endowed with adaptive scalabili

94 y outbred rats and reflect instead voluntary rodent behavior unrelated to genetic manipulation or to

95 y in humans, and may instead reflect typical rodent behavior.

96 protein quality of red and green lentils, a rodent bioassay was conducted and compared to an in vitr

97 As male and female neurons in rodent BLA responded differently to aromatase inhibition

98 -derived E2 modulates synaptic plasticity in rodent BLA sex-dependently.

99 ons and subsequent Abeta37 increases in both rodent brain and CSF at 30 mg/kg dosed orally.

100 and continuous redistribution across healthy rodent brain nuclei over a 2-week timeframe, whereas in

101 1 in neuronal culture, IL-34 expression in a rodent brain slice model with intact neuron-microglial n

102 ity of MALDI-IMS to image neuronal lipids in rodent brain tissue with subsequent immunohistochemistry

103 Resting levels of O2 in the rodent brain varied between 6.6 +/- 0.7 muM in the denta

104 03 accumulates at high concentrations in the rodent brain, where it rapidly lowers Abeta levels.

105 xpressed exclusively by neurons in the adult rodent brain.

106 cattering has limited its application in the rodent brain.

107 inistration leads to dopamine release in the rodent brain.

108 lexible open mesh electronics implanted into rodent brains by syringe injection that exhibit promisin

109 Sparsity can be quantified in freely moving rodents, but extrapolating these data to humans assumes

110 ause lasting changes in dopamine function in rodents, but it is not known if this occurs in humans.

111 ve recently been established successfully in rodents, but new infrastructures are needed to enable th

112 In rodents, caloric restriction and young blood-induced rev

113 This novel task shows that freely moving rodents can make simultaneous bilateral tactile discrimi

114 ntify genetic regulators of PGRN levels in a rodent cell-based model system.

115 ciated ubiquitin-conjugating enzyme UBC13 in rodent cerebellar granule neurons robustly increases the

116 rom 19 different CC lines were maintained on rodent chow diet for 8 weeks and were subsequently trans

117 In male rodents, chronic variate stress (CVS) has been shown to

118 Rodents chronically administered loop diuretics develop

119 nd cell surface presentation of Frizzled3 in rodent commissural axon growth cones.

120 Modern desert rodent communities are thought to be strongly structured

121 tly not due to reduced tendency to carry out rodent control.

122 tified a 4'-CN group that improved the human/rodent correlation in microsomal metabolic stability.

123 In rodents, cue-induced drug seeking requires transient syn

124 Adult neurogenesis persists in the rodent dentate gyrus and is stimulated by chronic treatm

125 Using an in vitro system, a rodent depression model, and a human postmortem brain, w

126 -3) polyunsaturated fatty acids (PUFAs) to a rodent diet reduces fat mass and prevents the developmen

127 PCP significantly reduced rodent duration MMN (p<0.001) and theta-band (p<0.01) re

128 Overall, we demonstrate that rodent duration MMN shows neuro-oscillatory signature si

129 al stem/stromal cells reduce the severity of rodent E. coli-induced acute respiratory distress syndro

130 rin in hippocampal and cortical neurons from rodent embryos of both sexes is distributed throughout t

131 d the hypothesis that, similar to humans and rodents, exercise training would enhance mitochondrial (

132 the pathogenesis of impaired RDD in diabetic rodents exhibiting features of painful neuropathy and th

133 nned behavior per session, making multitrial rodent experimental tools available to study planning.

134 Rodent experiments indicate that environmental exposures

135 Unlike humans, rodents express a novel isoform of ERbeta (mERbeta2) wit

136 tranasally administered ST266 accumulated in rodent eyes and optic nerves, attenuated visual dysfunct

137 ast; human cancer cells/red blood cells; and rodent fibroblasts/red blood cells.

138 n nuclei over a 2-week timeframe, whereas in rodents following photothrombotic cortical injury, trans

139 s have existed in their hosts, the New World rodents, for millions of years.

140 d quantify removal rates of hopbush seeds by rodents from enriched seed patches.

141 n of economic principles to operant tasks in rodents have allowed for the within-subject, within-sess

142 Studies in rodents have shown that mutants for Disrupted-In-Schizop

143 Studies in rodents have suggested that exercising behavioral contro

144 Analyses in rodents have used a limited number of spectro-temporal m

145 to those proposed in theoretical models for rodent head direction cells.

146 carnitine palmitoyl transferase I in normal rodent hearts has been shown to recapitulate the reduced

147 ations in the 6- to 10-Hz range dominate the rodent hippocampal local field potential during translat

148 In rodents, hippocampal LTP may be induced through electric

149 In rodents, hippocampal replay occurs during local sharp-wa

150 uent in epileptic compared with nonepileptic rodents; however, this feature showed limited predictive

151 nd meta-analysis of dopamine measures in the rodent, human and primate brain following acute and chro

152 Rodent imaging usually involves anaesthetising the anima

153 ife social stress in mental illness, rearing rodents in persistent postweaning social isolation has b

154 ns associated with Ebola virus adaptation to rodents in the proteins GP, NP, L, VP24 and VP35.

155 The observational fear (OF) paradigm in rodents, in which the subject is exposed to a distressed

156 The rodent incisor-which grows continuously throughout the l

157 ungulates, and primates but are not found in rodents, indicating fundamental differences in selective

158 In diabetic rodents, inhibition of MGO prevents cardiovascular disea

159 SIGNIFICANCE STATEMENT The whisker system of rodents is a widely used model to study tactile processi

160 vent in the myocardium of obese and diabetic rodents is an increase in docosahexaenoic acid (DHA) lev

161 Whereas islet architecture in rodents is distinctly different from humans, canine panc

162 s in human society, but whether it exists in rodents is unclear.

163 se results show that the adult sheep, unlike rodents, is largely endowed with non-newly generated neu

164 critical marker of islet integrity following rodent islet isolation.

165 as been almost exclusively examined in adult rodent learning models, but may be especially important

166 y less predictable than those of quadrupedal rodents, likely increasing predator evasion ability.

167 abricated and non-surgically inserted into a rodent lower digestive track to improve the imaging qual

168 for adhesion during gliding motility in the rodent malaria model P. berghei.

169 against sporozoite challenge in a stringent rodent malaria model.

170 Using rodent malaria models, we previously showed that TMP-SMX

171 blood-stage infections of two strains of the rodent malaria parasite Plasmodium chabaudi that differ

172 In rodents, many stress susceptibility and resilience studi

173 b2 levels are downregulated in the embryonic rodent midbrain during the period of dopaminergic axon g

174 s after multiple introductions of infectious rodents migrating from neighbouring areas.

175 ere, we evaluate physiological properties of rodent MMN, along with sensitivity to NMDAR agonist and

176 efore, the current study sought to develop a rodent model of adolescent cannabinoid self-administrati

177 ion on depressive and anxiety behaviors in a rodent model of chronic unpredictable stress (CUS).

178 l defeat stress (CSDS) is a well-established rodent model of depression that induces persistent socia

179 fasting hyperglycemia and ketoacidosis in a rodent model of DKA versus the chronic pleotropic effect

180 ve as a successful vaccination platform in a rodent model of Ebola virus disease and that GP1 N-glyca

181 We have previously established a rodent model of Meth-induced increases in sexual motivat

182 for reducing perioperative hemorrhage in the rodent model of surgical brain injury (SBI).

183 h leptin reverses hyperglycemia in a non-DKA rodent model of T1D.

184 We present a novel rodent model to reproduce much of the known phenotype of

185 ce (PVM) infection has been widely used as a rodent model to study the closely related human respirat

186 genetically defined autism risk alleles and rodent model, these findings suggest a conceptual framew

187 Using the female rodent model, we review our current understanding of est

188 to changes in bone structure, using a sepsis rodent model.

189 89)Zr-deferoxamine (Df)-pembrolizumab in two rodent models (mice and rats).

190 a pathogenicity factor for leishmaniasis in rodent models and human disease, and associated with dru

191 we discuss and assess the validity of seven rodent models currently used to assess antidepressant on

192 We discuss data from rodent models demonstrating the essential role of the gu

193 ell studied as reference compound for H3R in rodent models for neurological diseases connected with n

194 One obstacle is that most rodent models have employed lighting conditions that cau

195 also in neurodevelopmental theories, because rodent models indicate a role for complement proteins in

196 c firing mode in two freely behaving genetic rodent models of absence epilepsy.

197 In rodent models of aging, these alterations are associated

198 sia, and nerve conduction slowing in diverse rodent models of diabetes.

199 Rodent models of graft-induced dyskinesias (GIDs) have b

200 reasing evidence, particularly in humans and rodent models of helminth infection, points towards a mu

201 copy to analyze urine samples collected from rodent models of inflammatory glomerulonephritis (GN) as

202 PN type-specific chemogenetic stimulation in rodent models of PD (PD mice) and L-DOPA-induced dyskine

203 RVX-297 also countered pathology in three rodent models of polyarthritis: rat and mouse collagen-i

204 rain regions in drug self-administration and rodent models of relapse.

205 inal light responses and visual behaviors in rodent models of Retinitis pigmentosa.

206 e been shown to influence disease outcome in rodent models of several cardiovascular conditions, such

207 nal neurons after optic nerve crush (ONC) in rodent models of visual system injury.

208 ct (for example, atorvastatin) in recognised rodent models or patients.

209 Rodent models reveal that disrupted maternal-infant inte

210 Parkinsonian rodent models show enhanced reinforcing effects of chron

211 eclinical studies have shown convincingly in rodent models that mesenchymal stromal cells can prolong

212 against a stringent sporozoite challenge in rodent models to malaria, where IgG2a antibodies were as

213 ulatory feedback loop of alcohol and FGF2 in rodent models.

214 ons in depressed patients and in preclinical rodent models.

215 -Eif4e axis was further validated across MIA rodent models.

216 lar pathology observed in Schwann cells from rodent models.

217 kely occurs in human athletes, as well as in rodent models.

218 erin in vitro and ameliorated skin damage in rodent models.

219 ormalities of human WM and effects of DBS to rodent models.SIGNIFICANCE STATEMENT Psychiatric disease

220 understanding perceptual decision making in rodents, monkeys, and humans.

221 In a rodent myositis model, [(18)F]FPTMP identified live bact

222 and is applied to virtually all parts of the rodent nervous system, including the spinal cord and pri

223 increased BACE1-mediated APP processing, in rodent neuroglial cultures and human APP-expressing Chin

224 Here we have employed a primary rodent neuronal culture model to study the cellular effe

225 nctional or hyperfunctional forms of Trio in rodent neurons in vitro.

226 and rodent Tau isoforms in primary forebrain rodent neurons.

227 -activated protein kinase kinases (MKKs) and rodent NLRP1B (NACHT leucine-rich repeat and pyrin domai

228 sum, Nmb is a selective marker of the RTN in rodents; Nmb-low neurons, the vast majority, are central

229 is review, we discuss emerging evidence from rodents, non-human primates, and humans that demonstrate

230 Assessment of the biodistribution in rodents of a prototypical Alexa647-labeled trivalent con

231 an generate synchronized oscillations in the rodent olfactory bulb.

232 e-gated chloride channel expressed in either rodent or human induced pluripotent stem cell-derived se

233 reported that cardiac RNA of both human and rodent origins induced cytokine production and immune ce

234 itionally, we generated two novel transgenic rodent P. berghei parasite lines, where the P. berghei c

235 By using GFP expressing sporozoites of the rodent parasite P. berghei we are able to robustly quant

236 The rodent parasite Plasmodium berghei has served as a model

237 motile and invasive stages of both human and rodent parasites.

238 miRNA deep-sequencing showed that human and rodent parathyroids share similar profiles.

239 Potent in vivo activity was demonstrated in rodent PD models by measuring the induction of FXR targe

240 04 significantly delayed tumor growth in all rodent pediatric xenograft models and extended animal su

241 hese series exhibited high oral exposures in rodent PK studies and demonstrated significant tumor gro

242 o individual-based long-term data for a wild rodent population and show that despite a positive assoc

243 actices that caused explosions in their host rodent populations.

244 Rodent prevalence was generally higher in rented (compar

245 we show that TDP-43 RNP granules in axons of rodent primary cortical neurons display liquid-like prop

246 d cells in the entorhinal cortex (EC) of the rodent, primate, and human provides a coordinate system

247 posure confers long-term habit biases across rodent-primate species.

248 gs are inconsistent with current theories of rodent/primate prefrontal functional similarity, and pro

249 lts to eutherian mammals (e.g., xenarthrans, rodents, primates).

250 according with previous results obtained in rodents, primates, humans, pigs, and dogs.

251 We report that chronic stress exposure in rodents produces abnormal evaluation of costs and benefi

252 istration of cis P-tau targeting antibody to rodents reduces or delays pathological features of TBI.

253 alth scientists to emerging population-based rodent resources.

254 F and S1452F) (S1413L, L1422F, and S1450F in rodents, respectively) displayed impaired binding to mem

255 irus (MRV), the first definitively described rodent roseolovirus, to our knowledge.

256 In a rodent sepsis model, trabecular bone strength is functio

257 s of cultured mammalian cells, worms, flies, rodents, simians, apes, and even humans, all indicate de

258 any of the age-related defects that occur in rodent skeletal muscle.

259 Rodents sniff in response to novel odors, reward expecta

260 ) can contribute to chimera formation in non-rodent species remains unknown.

261 dentia associated UMRV and spillover between rodent species, most probably Rattus rattus, were detect

262 Rodent-specific and primate-specific hypomethylated regi

263 We identified a rodent-specific long non-coding RNA (lncRNA) linc1281, h

264 ation, despite implantation into the injured rodent spinal cord, yet they support delayed functional

265 erentiated, matured, and integrated into the rodent spinal cords over a time frame that aligned with

266 tation in lamina I and II neurons within the rodent spinal dorsal horn, a principal site of action fo

267 se CR+ interneurons are relatively scarce in rodent striatum, little is known about their molecular a

268 Results from preclinical rodent studies during the last 20 years implicated gluta

269 Rodent studies have begun to elucidate a role of Cav1.3

270 ABSTRACT: Extensive rodent studies have shown that reduced perinatal nutriti

271 Rodent studies showed that pre-exposure to a context tha

272 Here, we focus on evidence from rodent studies, highlighting recent findings of early an

273 skers is required in an increasing number of rodent studies.

274 dministration, in concordance with human and rodent studies.

275 In rodents, subtype classification has associated subtypes

276 ty years of electrophysiological research in rodents suggest that cognitive maps are neurally instant

277 L-23/acutely transforming retrovirus AKT8 in rodent T-cell lymphoma/signal transducer and activator o

278 he properties and distributions of human and rodent Tau isoforms in primary forebrain rodent neurons.

279 injury using testicular cells isolated from rodent testes, but it remains unknown if PFOS has simila

280 in one of the output nuclei of the BG of the rodent, the entopeduncular nucleus (EP).

281 Our study in a diurnal rodent, the Grass rat, indicates that sleep deprivation

282 In humans and rodents, the medial prefrontal cortex (mPFC) has been im

283 In rodents, these receptors are also expressed by sensory n

284 ocused on females because in both humans and rodents, they experience a 2-fold increase in mood disor

285 armacology and optogenetics in freely moving rodents.This protocol is an extension to: Nat.

286 esents the progress that has been made using rodents to establish the motor cortex as an adaptive str

287 n propinquity, the tendency of freely mobile rodents to maintain close physical proximity, and assess

288 d none measures propinquity, the tendency of rodents to maintain close physical proximity.

289 ross-species jumps of gammaretroviruses from rodents to primates and marsupials.

290 The diversity of ipRGCs varies from rodents to primates, suggesting differences in their con

291 opmental compensation for loss of torsinA in rodents, torsinA knockdown in the immature cerebellum fa

292 In rodents, URMC-099 activation of autophagy led to 50-fold

293 distribution of functional SGLT2 proteins in rodents using positron emission tomography with 4-[(18)F

294 t view by showing that theta oscillations in rodent V1 may come to convey timed expectations.

295 vel, unrestrained virtual reality system for rodents, we discovered that a new experience increased f

296 rmalin-, carrageenan- or FCA-induced pain in rodents when administered systemically.

297 rticostriatal glutamatergic terminals in the rodent with brain iron deficiency (BID), a pathogenetic

298 Immunization of rodents with BBI39, or a diverse paralog, BBI36, or thei

299 in adult naked mole-rats, the longest living rodent, with a maximum life span exceeding 30 years, and

300 ng isotopic tracers for metabolic studies in rodents without overt stress is challenging.